???global.info.a_carregar???
Tânia Vieira Madureira is a Researcher at CIIMAR - University of Porto and an Invited Associate Professor at ICBAS - University of Porto. Teaching activity includes curricular units from different courses, namely Integrated Master Degree in Medicine and Dental Medicine, Master Degree in Environmental Contamination and Toxicology, Master Degree in Marine Sciences - Marine Resources and Master Degree in Oncology. She received her degree in Pharmaceutical Sciences in 2005 and her PhD in 2011 in Biomedical Sciences from ICBAS, in collaboration with Federal University of São Carlos, Brazil. She was a postdoc at CIIMAR from 2011 to 2018. She supervised/co-supervised Degree/MSC/PhD students. She authored/co-authored more than 35 articles in journals and 1 section book. Her actual research interests focus on fish physiology and endocrinology, fish endocrine disruption, in vivo and in vitro fish models. Currently, her main focus is on three-dimensional (3D) hepatocyte cultures, namely spheroids, as new alternative models for hepatotoxicity and (eco)toxicological applications. She has a large experience with fish handling in laboratory and field conditions, certified by Direção Geral de Alimentação e Veterinária (DGAV) as accredited to conduct animal procedures and design of procedures and projects (Research Coordinator).
Read full resume ↓
Identification

Personal identification

Full name
Tânia Vieira Madureira

Citation names

  • Madureira, Tânia
  • Tânia V. Madureira
  • Madureira, Tânia Vieira
  • Madureira, T. V.
  • Vieira Madureira, Tânia
  • T. V., Madureira

Author identifiers

Ciência ID
2F1F-E14E-4257
ORCID iD
0000-0001-9354-4290

Email addresses

  • taniavmad@hotmail.com (Personal)

Websites

Knowledge fields

  • Medical and Health Sciences - Medical Biotechnology - Technologies Involving the Manipulation of Cells, Tissues, Organs or the Whole Organism
  • Exact Sciences - Chemical Sciences - Analytical Chemistry
  • Agrarian Sciences - Animal and Dairy Science - Husbandry
  • Medical and Health Sciences - Clinical Medicine - Endocrinology and Metabolism
  • Natural sciences - Biological Sciences - Molecular Biology
  • Natural sciences - Biological Sciences - Behavioural Sciences Biology
  • Natural sciences - Earth and Environmental Sciences - Environmental Sciences
  • Natural sciences - Biological Sciences - Cell Biology

Languages

Language Speaking Reading Writing Listening Peer-review
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
French Intermediate (B1) Upper intermediate (B2) Intermediate (B1) Upper intermediate (B2) Intermediate (B1)
Spanish; Castilian Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2)
Portuguese (Mother tongue)
Education
Degree Classification
2011/05/27
Concluded
 Biomedical Sciences (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
"Analysis of pharmaceuticals in the Douro River estuary and test of biological effects using zebrafish as a model" (THESIS/DISSERTATION)
 Approved by unanimity and distinction
2005/07
Concluded
 Pharmaceutical Sciences (Licenciatura)
Instituto Universitário de Ciências da Saúde, Portugal
"n/a" (THESIS/DISSERTATION)
 16 (in 20)
Affiliation

Science

Category
Host institution 		Employer
2024/10/01 - Current Researcher (Research) Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2018/10/01 - 2024/09/30 Contracted Researcher (Research) Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2014/08/01 - 2018/09/30 Postdoc (Research) Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2011/12/01 - 2014/07/31 Postdoc (Research) Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal

Teaching in Higher Education

Category
Host institution 		Employer
2024/10/01 - Current Invited Associate Professor (University Teacher) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2011/08/30 - 2024/08/31 Invited Assistant Professor (University Teacher) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Other Careers

Category
Host institution 		Employer
2005/07/01 - 2006/12/01 Técnico Farmacêutico Especialista (Técnico Farmacêutico) Farmácia Lima, Portugal

Others

Category
Host institution 		Employer
2007/01/01 - 2010/12/01 PhD fellow (SFRH/BD/31382/2006), in collaboration with Federal University of São Carlos, Brazil Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Projects

Grant

Designation Funders
2011/12/01 - 2014/07/31 Peroxissomes, estrogens and nuclear receptors: Cross-talk evaluation in hepatocytes of a fish model organism
PTDC/CVT/115618/2009
Post-doc Fellow
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2007/01/01 - 2010/12/31 Analysis of pharmaceuticals in the Douro River Estuary and test of biological effects using zebrafish as a model
SFRH/BD/31382/2006
PhD Student Fellow
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded

Other

Designation Funders
2021 - 2023 ATLANTIDA - Platform for the monitoring of the North Atlantic ocean and tools for the sustainable exploitation of the marine resources
ATLANTIDA
Researcher
Comissao de Coordenacao e Desenvolvimento Regional do Norte
Concluded
2021/11/01 - 2022/10/31 SPHEROTOX - Warming impacts on estrogenic and progestagenic endocrine disruptors effects in fish liver - A proof of concept study using single- and novel multi-cell 3D cultures of the European native brown trout
101038087
Researcher
Concluded
2018 - 2021/05/31 Impacts of global change on environmentally realistic mixtures of endocrine disruptor compounds on the structure and functioning of coastal ecosystems? Implications for a sustainable environment
PTDC/BIA-ECO/30552/2017
Researcher
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2016/01/01 - 2018/12/31 INNOVMAR - Innovation and sustainability in the management and exploitation of marine resources
NORTE-01-0145-FEDER-000035
Post-doc
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
 Comissao de Coordenacao e Desenvolvimento Regional do Norte
Concluded
2014/01/01 - 2015/06/30 ECORISK - Ecological risk assessment of oils and hazardous and noxious substances in the NW Portuguese coast
NORTE-07-0124-FEDER-000055
Post-doc
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
Concluded
2013/01/01 - 2015/06/30 MARBIOTECH - Survey of natural substances from marine organisms with potential pharmacological and ecological applications
NORTE-07-0124-FEDER-000047
Post-doc
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
 Agência Nacional de Inovação SA
Concluded
2008/10/01 - 2012/06/30 An integrative study on the toxicopathic lesions in Portuguese estuarine fishes - Assessing injury impact and toxicogenomic implications in experimental models.
info:eu-repo/grantAgreement/FCT/5876-PPCDTI/70436/PT
Other
Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Book chapter
  1. Tânia V. Madureira; Ana Rita Ribeiro; Maria Elizabeth Tiritan. "Quantificação de fármacos no ambiente". In Cromatografia Líquida. São Paulo, Brazil: Elsevier, 2015.
Conference poster
  1. Rodrigo Alves; Célia Lopes; Eduardo Rocha; Madureira, Tânia Vieira. "Application of brown trout primary hepatocytes spheroids to test 17alpha-ethinylestradiol effects". Paper presented in XIV Congress of the Iberian Association of Comparative Endocrinology - AIEC, 2023.
  2. Madureira, Tânia Vieira; Rodrigo Alves; Célia Lopes; Bozidar Raskovic; Eduardo Rocha. "Brown trout primary hepatocyte spheroids - Characterization and applications in endocrinology and beyond". Paper presented in XIV Congress of the Iberian Association of Comparative Endocrinology - AIEC, 2023.
  3. Madureira, Tânia Vieira; Diana Santiago Santos; Tiago Simões; Lemos, Marco F. L.; Eduardo Rocha. "Liver and plasma fatty acid profiles in female brown trout along distinct reproductive stages". Paper presented in XIV Congress of the Iberian Association of Comparative Endocrinology - AIEC, 2023.
  4. Rodrigo F. Alves; Célia Lopes; Eduardo Rocha; Tânia V. Madureira. "Brown trout primary hepatocyte spheroids - A model to assess estrogenic effects". Paper presented in European Society for Comparative Endocrinology (ESCE) and the International Society of Fish Endocrinology - ISFE, 2022.
  5. Božidar Raškovic; Tânia V. Madureira; Célia Lopes; Eduardo Rocha. "The effects of two progestins and 17alpha-ethinylestradiol on cultured hepatocyte spheroids of brown trout (Salmo trutta)". 2022.
  6. Rodrigo F. Alves; Célia Lopes; Eduardo Rocha; Tânia V. Madureira. "Morphological and functional characterization of brown trout primary hepatocyte spheroids". Paper presented in SETAC Europe 32nd Annual Meeting, 2022.
  7. Diana Santos; Eduardo Rocha; Célia Lopes; Fernanda Malhão; J.F. Gonçalves; Tânia V. Madureira. "Expression of estrogenic biomarkers in the liver of brown trout males in distinct reproductive phases". Paper presented in XIII Congress of the Iberian Association of Comparative Endocrinology - AIEC, 2021.
  8. Diana Santiago Santos; Eduardo Rocha; Fernanda Malhão; Célia Lopes; José Fernando Gonçalves; Tânia V. Madureira. "Gonadal staging and selected biometric and blood parameters along a breeding cycle of brown trout cultured in Portugal (North)". Paper presented in 2021 Annual Symposium of the Fisheries Society of the British Isles, 2021.
  9. Maria João Rocha; Joana F. Oliveira; Tânia V. Madureira; Eduardo Rocha. "One-year-old brown trout juveniles are often experimentally dealt with as equals regarding morphological characteristics and sex-hormonal profile, but, are, are they?". Paper presented in 2021 Annual Symposium of the Fisheries Society of the British Isles, 2021.
  10. Célia Lopes; Eduardo Rocha; Inês Lopes Pereira; Tânia V. Madureira. "Testosterone and dihydrotestosterone effects on lipid-related genes in brown trout primary hepatocytes suggest that xenoandrogens may disrupt lipid metabolism in fish". Paper presented in SETAC Europe 31st Annual Meeting, 2021.
  11. Célia Lopes; Tânia V. Madureira; José F. Gonçalves; Eduardo Rocha. "Can androgens modulate classic estrogenic targets in brown trout primary hepatocytes?". Paper presented in SETAC Europe 30th Annual Meeting, 2020.
    10.1158/1535-7163.targ-11-pl05-04
  12. Inês Pereira; Célia Lopes; Eduardo Rocha; Tânia V. Madureira. "Three-dimensional (3D) brown trout primary hepatocyte model for assessing 5alpha-dihydrotestosterone effects on lipidic target genes". Paper presented in SETAC Europe 30th Annual Meeting, 2020.
    10.1117/12.2037310
  13. Diana Santos; Tânia V. Madureira; Fernanda Malhão; Célia Lopes; José F. Gonçalves; Eduardo Rocha. "Immunohistochemical location of CYP17, 17beta-HSD and CYP19 in adult brown trout male gonads at pre-spawning and post-spawning phases". Paper presented in 31st Congress of New European Society for Comparative Physiology and Biochemistry, 2018.
  14. Célia Lopes; Tânia V. Madureira; Fernanda Malhão; José F. Gonçalves; Eduardo Rocha. "Exploring the effects of androgens in estrogenic targets using primary hepatocytes from brown trout (Salmo trutta fario)". Paper presented in 31st Congress of New European Society for Comparative Physiology and Biochemistry, 2018.
  15. Tânia V. Madureira; Joana Luísa Costa; Fernanda Malhão; Célia Lopes; José F. Gonçalves; Eduardo Rocha. "Physiological and behavioural effects of an acute stress event in brown trout juveniles". Paper presented in 29th Conference of European Comparative Endocrinologists, 2018.
  16. Inês Mota; Eduardo Rocha; Sofia Abrunheiro; Célia Lopes; Fernanda Malhão; José F. Gonçalves; Tânia V. Madureira. "Can a single exposure event of 17alpha-ethinylestradiol and/or clofibrate influence some weeks later either estrogenic or lipidic pathways in brown trout larvae?". Paper presented in 29th Conference of European Comparative Endocrinologists, 2018.
  17. Sofia Abrunheiro; José F. Gonçalves; Eduardo Rocha; Tânia V. Madureira. "Effects of intraperitoneal injection of ethinylestradiol and clofibrate in brown trout (Salmo trutta f. fario) females". Paper presented in XI Congress of Iberian Association for Comparative Endocrinology, 2017.
  18. Célia Lopes; Eduardo Rocha; Ivone Pinheiro; Luís Filipe Castro; Tânia V. Madureira. "Testosterone modulates both estrogenic signaling and peroxisome-related genes in brown trout (Salmo trutta f. fario) primary hepatocytes". Paper presented in XI Congress of Iberian Association for Comparative Endocrinology, 2017.
  19. Tânia V. Madureira; Fernanda Malhão; Tiago Simões; Ivone Pinheiro; Célia Lopes; José F. Gonçalves; Ralph Urbatzka; et al. "Estrogenic disruption of lipid metabolic signalling in juvenile brown trout (Salmo trutta f. fario)". Paper presented in 50th Anniversary Symposium of the Fisheries Society of the British Isles, 2017.
  20. Sofia Abrunheiro; Fernanda Malhão; Célia Lopes; Eduardo Rocha; Tânia V. Madureira. "Studying effects of oestrogens and of PPAR agonists in the development of eyed-stage embryos of brown trout (Salmo trutta f. fario)". Paper presented in 50th Anniversary Symposium of the Fisheries Society of the British Isles, 2017.
  21. Daniela Rodrigues; Patrícia Cardoso; Nádia Oliveira; Fernanda Malhão; Tânia V. Madureira; Eduardo Rocha. "Effects of a synthetic progestin on the zebrafish gonadal maturation - Preliminary histopathology study with a supra-environmental concentration of levonorgestrel". Paper presented in 50th Meeting of SPMicros - Microscopy and Microanalysis in Materials and Life Sciences, 2016.
  22. Tânia V. Madureira; Ivone Pinheiro; Fernanda Malhão; Célia Lopes; Ralph Urbatzka; José F. Gonçalves; Luís Filipe Castro; Eduardo Rocha. "Interference of estrogenic and androgenic inputs in the brown trout lipid metabolism - Experimental biochemical and molecular studies". Paper presented in 10th Iberian and 7th Iberoamerican Congress on Environmental Contamination and Toxicology, 2015.
  23. Tânia V. Madureira; Ivone Pinheiro; Fernanda Malhão; Célia Lopes; Ralph Urbatzka; José F. Gonçalves; Luís Filipe Castro; Eduardo Rocha. "Molecular and ultrastructural effects of sex-steroids and a lipid modulator in brown trout liver after sub-acute in vivo exposures". Paper presented in 18th Pollutant Responses in Marine Organisms, 2015.
  24. Paula Silva; Patrícia Machado; Catarina Cruzeiro; Ana Fernandes; Fernanda Malhão; Célia Lopes; Tânia V. Madureira; Eduardo Rocha. "Effects of an acute exposure of fluoxetine in the night prior to spawning on reproductive performance and development of zebrafish (Danio rerio)". Paper presented in XX Meeting of the Portuguese Society of Animal Pathology - Fish Pathology, 2015.
  25. Tânia V. Madureira; Fernanda Malhão; Cláudia Guimarães; Célia Lopes; Eduardo Rocha. "Uncovering morphological interferences caused by androgen inputs in peroxisomes from primary brown trout hepatocytes using catalase immunofluorescence". Paper presented in International Conference on Microscopy and Microanalysis, XLVIII Congress of the Portuguese Microscopy Society, 2014.
  26. Tânia V. Madureira; Fernanda Malhão; Célia Lopes; Ivone Pinheiro; José F. Gonçalves; Eduardo Rocha. "Morphological alterations caused by estrogenic and anti-estrogenic signaling in peroxisomes of primary brown trout hepatocytes – Stereological approach using catalase immunofluorescence". Paper presented in International Conference on Microscopy and Microanalysis, XLVIII Congress of the Portuguese Microscopy Society, 2014.
  27. Ivone Pinheiro; Fernanda Malhão; Tânia V. Madureira; Maria João Rocha; Rogério A. F. Monteiro; Eduardo Rocha. "Ethinylestradiol exposure of primary culture brown trout hepatocytes induce morphological changes in peroxisomes". Paper presented in International Conference on Microscopy and Microanalysis, XLVIII Congress of the Portuguese Microscopy Society, 2014.
  28. Tânia V. Madureira; Célia Lopes; Fernanda Malhão; José F. Gonçalves; Eduardo Rocha. "Stereological estimation of volume densities of hepatocytic peroxisomes in brown trout after estrogenic exposures by catalase immunofluorescence". Paper presented in 27th Conference of European Comparative Endocrinologists, 2014.
  29. Tânia V. Madureira; Luís Filipe Castro; Ivone Pinheiro; Ralph Urbatzka; Eduardo Rocha. "Looking for estrogenic and anti-estrogenic modulation in primary cultured brown trout hepatocytes". Paper presented in 27th Conference of European Comparative Endocrinologists, 2014.
  30. Célia Lopes; Tânia V. Madureira; Fernanda Malhão; Ivone Pinheiro; Luís Filipe Castro; Eduardo Rocha. "In vitro exposure of brown trout hepatocytes to testosterone – Role in estrogen and peroxisomal pathways". Paper presented in 27th Conference of European Comparative Endocrinologists, 2014.
  31. Eduardo Rocha; Albina Dolores Resende; Maria João Rocha; Fernanda Malhão; Tânia V. Madureira; Rogério A. F. Monteiro; Alexandre Lobo-da-Cunha. "Stereology of brown trout liver peroxisomes at vitellogenesis and pre-spawning strengthens the hypothesis of regulation of those organelles by sex steroids". Paper presented in 27th Conference of European Comparative Endocrinologists, 2014.
  32. Tânia V. Madureira; Luís Filipe Castro; Nádia Ferreira; Ivone Pinheiro; Fernanda Malhão; Ralph Urbatzka; Eduardo Rocha. "Ethinylestradiol exposure of primary cultured brown trout hepatocytes mimics in vivo estrogenic effects – Part II: Molecular approach". Paper presented in 17th Pollutant Responses in Marine Organisms, 2013.
  33. Tânia V. Madureira; Cláudia Santos; Susana Velhote; Catarina Cruzeiro; Eduardo Rocha; Maria João Rocha. "Intersex differences in the load of polychlorinated biphenyls in wild vs. commercial mussels (Mytilus sp.) from the north west of the Iberian Peninsula". Paper presented in 17th Pollutant Responses in Marine Organisms, 2013.
  34. Maria João Rocha; Susana Velhote; Cláudia Santos; Catarina Cruzeiro; Eduardo Rocha; Tânia V. Madureira. "Load of polycyclic aromatic hydrocarbons in wild vs. commercial mussels (Mytilus sp.) caught in the north west of the Iberian Peninsula". Paper presented in 17th Pollutant Responses in Marine Organisms, 2013.
  35. Catarina Cruzeiro; Susana Velhote; Tânia V. Madureira; Cláudia Santos; Eduardo Rocha; Maria João Rocha. "Looking for intersex differences in the body burden of polycyclic aromatic hydrocarbons in mussels (Mytilus sp.) from the north west coast of Portugal". Paper presented in 17th Pollutant Responses in Marine Organisms, 2013.
  36. Tânia V. Madureira; Maria João Rocha; Catarina Cruzeiro; Iolanda Rodrigues; Rogério A. F. Monteiro; Eduardo Rocha. "The toxicity potential of pharmaceuticals found in the Douro River estuary (Portugal) - Part I: Evaluation of liver impacts in zebrafish after sub-acute exposures". Paper presented in 21th Annual Meeting of the Society of Environmental Toxicology and Chemistry Europe, 2011.
  37. Tânia V. Madureira; Maria João Rocha; Catarina Cruzeiro; Maria Helena Galante; Rogério A. F. Monteiro; Eduardo Rocha. "The toxicity potential of pharmaceuticals found in the Douro River estuary (Portugal) - Part II: Assessment of impacts in the maturation of zebrafish gonads after sub-acute exposures". Paper presented in 21th Annual Meeting of the Society of Environmental Toxicology and Chemistry Europe, 2011.
  38. Tânia V. Madureira; Catarina Cruzeiro; Maria João Rocha; Eduardo Rocha. "The toxicity potential of pharmaceuticals found in the Douro River estuary (Portugal) - Part III: Experimental assessment of gross developmental defects using the zebrafish embryo test". Paper presented in 21th Annual Meeting of the Society of Environmental Toxicology and Chemistry Europe, 2011.
  39. Tânia V. Madureira; Cristina M. C. M. Couto; Juliana C. Barreiro; Quezia B. Cass; Ivone Pinto; Maria João Rocha; Agostinho A. Almeida; Maria Elizabeth Tiritan. "Evaluation of the influence of WWTPs on estuarine water quality - Correlation between a sewage molecular marker and the metal content in surface waters of the Douro estuary (Portugal)". Paper presented in 20th Annual Meeting of the Society of Environmental Toxicology and Chemistry Europe, 2010.
  40. Alexandra Maia; Ana Rita Ribeiro; Virgínia Gonçalves; M. F. Carvalho; Tânia V. Madureira; Paula Castro; Maria Elizabeth Tiritan. "HPLC-DAD method validation for monitoring microbial degradation of several pharmaceuticals". Paper presented in 20th Annual Meeting of the Society of Environmental Toxicology and Chemistry Europe, 2010.
  41. Cristina M. C. M. Couto; Ivone Pinto; Tânia V. Madureira; Maria João Rocha; Maria Elizabeth Tiritan; Agostinho A. Almeida. "Spatiotemporal distribution of metals in the Douro River estuary (Portugal)". Paper presented in 20th Annual Meeting of the Society of Environmental Toxicology and Chemistry Europe, 2010.
  42. Cristina M. C. M. Couto; Ivone Pinto; Tânia V. Madureira; Maria João Rocha; Maria Elizabeth Tiritan; Agostinho A. Almeida. "Evaluation of the influence of WWTPs on estuarine water quality - anthropogenic influences on metal content in surface waters of the Douro River estuary (Portugal)". Paper presented in 20th Annual Meeting of the Society of Environmental Toxicology and Chemistry Europe, 2010.
  43. Juliana C. Barreiro; Bruna N. O. C. Moreira; Tânia V. Madureira; Kenia L. Vanzolini; Maria Elizabeth Tiritan; Quezia B. Cass. "Study of the use of restricted-access media columns, type immobilized protein, as sample pre-treatment for the quantification of a series of pharmaceutical compounds in wastewater". Paper presented in 17th Meeting of the Brazilian Chemical Society - Regional Interior Paulista Waldemar Saffioti, 2009.
  44. Tânia V. Madureira; Maria João Rocha; Quezia B. Cass; Maria Elizabeth Tiritan. "Pharmaceutical trace analysis in aqueous environmental matrices by liquid chromatography ion trap tandem mass spectrometry". Paper presented in 34th International Symposium on High Performance Liquid Phase Separations and Related Techniques, 2009.
  45. Juliana C. Barreiro; Tânia V. Madureira; Kenia L. Vanzolini; Maria João Rocha; Maria Elizabeth Tiritan; Quezia B. Cass. "Evaluation of Restricted-Access Medium (RAM) columns in the macromolecules exclusion from estuarine and residual water samples". Paper presented in XII Latin American Congress of Chromatography and Related Techniques, 2008.
  46. Tânia V. Madureira; Maria João Rocha; Eduardo Rocha; Quezia B. Cass; Maria Elizabeth Tiritan. "HPLC-DAD for screening of pharmaceuticals from different therapeutic classes in Douro River estuary". Paper presented in 18th Annual Meeting of the Society of Environmental Toxicology and Chemistry Europe, 2008.
  47. Tânia V. Madureira; Maria João Rocha; Quezia B. Cass; Maria Elizabeth Tiritan. "Development and optimization of a multi-residue HPLC-DAD method for analysis of pharmaceuticals in surface waters". Paper presented in 32nd International Symposium on High Performance Liquid Phase Separations and Related Techniques, 2008.
  48. Tânia V. Madureira; Maria João Rocha; Eduardo Rocha; Quezia B. Cass; Maria Elizabeth Tiritan. "Simultaneous analysis of several classes of pharmaceuticals in surface waters by solid-phase extraction and HPLC-DAD". Paper presented in II National Meeting of Bromatology, Hydrology and Toxicology, 2008.
  49. Tânia V. Madureira; Maria João Rocha; Eduardo Rocha; Quezia B. Cass; Maria Elizabeth Tiritan. "Development and optimization of an extraction method for the analysis of different therapeutic pharmaceuticals in surface waters". Paper presented in 5th National Chromatography Meeting, 2007.
Journal article
  1. Rodrigo Alves; Célia Lopes; Eduardo Rocha; Tânia V. Madureira. Corresponding author: Tânia V. Madureira. "Estrogenic responsiveness of brown trout primary hepatocyte spheroids to environmental levels of 17alpha-ethinylestradiol". Journal of Xenobiotics 14 3 (2024): 1064-1078.
    Open access • Published
  2. Tiago Lourenço; Eduardo Rocha; José Fernando Gonçalves; Maria João Rocha; Madureira, Tânia Vieira. "A proof-of-concept for a hypolipidemic brown trout model". Toxics 12 3 (2024): 219. https://doi.org/10.3390/toxics12030219.
    Open access • Published • 10.3390/toxics12030219
  3. Lourenço, Tiago; Madureira, Tânia Vieira; Rocha, Maria João; Rocha, Eduardo. "Fish as models to study liver and blood lipid-related effects of fibrates and statins and screen new hypolipidemic drugs". Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 274 (2023): 109756. http://dx.doi.org/10.1016/j.cbpc.2023.109756.
    Open access • Published • 10.1016/j.cbpc.2023.109756
  4. Madureira, Tânia Vieira; Santos, Diana; Simões, Tiago; Lemos, Marco F. L.; Rocha, Eduardo. "Liver and plasma fatty acid characterization in cultured brown trout at distinct reproductive stages". Biology 12 11 (2023): 1434. http://dx.doi.org/10.3390/biology12111434.
    Open access • Published • 10.3390/biology12111434
  5. Alves, Rodrigo F.; Lopes, Célia; Rocha, Eduardo; Madureira, Tânia V.. "A step forward in the characterization of primary brown trout hepatocytic spheroids as experimental models". Animals 13 14 (2023): 2277. http://dx.doi.org/10.3390/ani13142277.
    Open access • Published • 10.3390/ani13142277
  6. Pereira, I.L.; Lopes, C.; Rocha, E.; Madureira, T.V.. "Establishing brown trout primary hepatocyte spheroids as a new alternative experimental model - Testing the effects of 5a-dihydrotestosterone on lipid pathways". Aquatic Toxicology 253 (2022): 106331. http://www.scopus.com/inward/record.url?eid=2-s2.0-85140808040&partnerID=MN8TOARS.
    Open access • Published • 10.1016/j.aquatox.2022.106331
  7. Alves, R.F.; Rocha, E.; Madureira, T.V.. "Fish hepatocyte spheroids - A powerful (though underexplored) alternative in vitro model to study hepatotoxicity". Comparative Biochemistry and Physiology Part - C: Toxicology and Pharmacology 262 (2022): 109470. http://www.scopus.com/inward/record.url?eid=2-s2.0-85138798711&partnerID=MN8TOARS.
    Open access • Published • 10.1016/j.cbpc.2022.109470
  8. Diana Santiago Santos; Eduardo Rocha; Fernanda Malhão; Célia Lopes; José Fernando Gonçalves; Tânia V. Madureira. "Multi-parametric characterization of brown trout fitness and gonadal maturation along the reproductive cycle". Animals 11 5 (2021): 1290. https://doi.org/10.3390/ani11051290.
    Open access • Published • 10.3390/ani11051290
  9. Célia Lopes; Eduardo Rocha; Inês Lopes Pereira; Tânia V. Madureira. "Deciphering influences of testosterone and dihydrotestosterone on lipid metabolism genes using brown trout primary hepatocytes". Aquatic Toxicology 235 (2021): 105819. https://doi.org/10.1016/j.aquatox.2021.105819.
    Published • 10.1016/j.aquatox.2021.105819
  10. Célia Lopes; Tânia V. Madureira; José F. Gonçalves; Eduardo Rocha. "Disruption of classical estrogenic targets in brown trout primary hepatocytes by the models androgens testosterone and dihydrotestosterone". Aquatic Toxicology 227 (2020): 105586. https://doi.org/10.1016/j.aquatox.2020.105586.
    Published • 10.1016/j.aquatox.2020.105586
  11. Vieira Madureira, Tânia; Costa, Joana Luísa; Malhão, Fernanda; Lopes, Célia; Gonçalves, José F.; Rocha, Eduardo. "Design of a multi-parametric profile for assessing the acclimation period of juvenile brown trout after an acute transport to new housing environment". Applied Animal Behaviour Science 219 (2019): 104835. http://dx.doi.org/10.1016/j.applanim.2019.104835.
    Published • 10.1016/j.applanim.2019.104835
  12. Rocha, M.J.; Madureira, T.V.; Venade, C.S.; Martins, I.; Campos, J.; Rocha, E.. "Presence of estrogenic endocrine disruptors in three European estuaries in Northwest Iberian Peninsula (Portugal)". Toxicological and Environmental Chemistry 101 3-6 (2019): 244-264. http://www.scopus.com/inward/record.url?eid=2-s2.0-85075390756&partnerID=MN8TOARS.
    Published • 10.1080/02772248.2019.1692019
  13. Madureira, T.V.; Pinheiro, I.; Malhão, F.; Castro, L.F.C.; Rocha, E.; Urbatzka, R.. "Silencing of PPARaBb mRNA in brown trout primary hepatocytes: effects on molecular and morphological targets under the influence of an estrogen and a PPARa agonist". Comparative Biochemistry and Physiology Part - B: Biochemistry and Molecular Biology 229 (2019): 1-9. http://www.scopus.com/inward/record.url?eid=2-s2.0-85058191717&partnerID=MN8TOARS.
    Published • 10.1016/j.cbpb.2018.12.001
  14. Madureira, T.V.; Malhão, F.; Simões, T.; Pinheiro, I.; Lopes, C.; Gonçalves, J.F.; Urbatzka, R.; et al. "Sex-steroids and hypolipidemic chemicals impacts on brown trout lipid and peroxisome signaling - Molecular, biochemical and morphological insights". Comparative Biochemistry and Physiology Part - C: Toxicology and Pharmacology 212 (2018): 1-17. http://www.scopus.com/inward/record.url?eid=2-s2.0-85048719472&partnerID=MN8TOARS.
    Published • 10.1016/j.cbpc.2018.06.001
  15. Cardoso, P.G.; Rodrigues, D.; Madureira, T.V.; Rocha, M.J.; Rocha, E.. "Histopathological Evaluation of Combined Impacts of the Synthetic Progestin Levonorgestrel and Temperature on the Female Zebrafish Maturation Using a Semi-quantitative Grading Analysis—Is it Enough?". Bulletin of Environmental Contamination and Toxicology 101 4 (2018): 417-422. http://www.scopus.com/inward/record.url?eid=2-s2.0-85052953203&partnerID=MN8TOARS.
    Published • 10.1007/s00128-018-2436-z
  16. Cardoso, P.G.; Rodrigues, D.; Madureira, T.V.; Oliveira, N.; Rocha, M.J.; Rocha, E.. "Warming modulates the effects of the endocrine disruptor progestin levonorgestrel on the zebrafish fitness, ovary maturation kinetics and reproduction success". Environmental Pollution 229 (2017): 300-311. http://www.scopus.com/inward/record.url?eid=2-s2.0-85020280208&partnerID=MN8TOARS.
    Published • 10.1016/j.envpol.2017.05.090
  17. Lopes, C.; Malhão, F.; Guimarães, C.; Pinheiro, I.; Gonçalves, J.F.; Castro, L.F.C.; Rocha, E.; Madureira, T.V.. "Testosterone-induced modulation of peroxisomal morphology and peroxisome-related gene expression in brown trout (Salmo trutta f. fario) primary hepatocytes". Aquatic Toxicology 193 (2017): 30-39. http://www.scopus.com/inward/record.url?eid=2-s2.0-85031046353&partnerID=MN8TOARS.
    Published • 10.1016/j.aquatox.2017.09.026
  18. Madureira, T.V.; Pinheiro, I.; de Paula Freire, R.; Rocha, E.; Castro, L.F.; Urbatzka, R.. "Genome specific PPARaB duplicates in salmonids and insights into estrogenic regulation in brown trout". Comparative Biochemistry and Physiology Part - B: Biochemistry and Molecular Biology 208-209 (2017): 94-101. http://www.scopus.com/inward/record.url?eid=2-s2.0-85018253413&partnerID=MN8TOARS.
    Published • 10.1016/j.cbpb.2017.04.005
  19. Madureira, T.V.; Pinheiro, I.; Malhão, F.; Lopes, C.; Urbatzka, R.; Castro, L.F.C.; Rocha, E.. "Cross-interference of two model peroxisome proliferators in peroxisomal and estrogenic pathways in brown trout hepatocytes". Aquatic Toxicology 187 (2017): 153-162. http://www.scopus.com/inward/record.url?eid=2-s2.0-85017559852&partnerID=MN8TOARS.
    Published • 10.1016/j.aquatox.2017.04.001
  20. Lopes, Célia; Madureira, Tânia Vieira; Ferreira, Nádia; Pinheiro, Ivone; Castro, L. Filipe C.; Rocha, Eduardo. "Peroxisome proliferator-activated receptor gamma (PPARgamma) in brown trout: Interference of estrogenic and androgenic inputs in primary hepatocytes". Environmental Toxicology and Pharmacology 46 (2016): 328-336. http://dx.doi.org/10.1016/j.etap.2016.08.009.
    Published • 10.1016/j.etap.2016.08.009
  21. Madureira, T.V.; Castro, L.F.C.; Rocha, E.. "Acyl-coenzyme A oxidases 1 and 3 in brown trout (Salmo trutta f. fario): Can peroxisomal fatty acid ß-oxidation be regulated by estrogen signaling?". Fish Physiology and Biochemistry 42 1 (2016): 389-401. http://www.scopus.com/inward/record.url?eid=2-s2.0-84957434362&partnerID=MN8TOARS.
    Published • 10.1007/s10695-015-0146-6
  22. Madureira, T.V.; Malhão, F.; Guimarães, C.; Lopes, C.; Rocha, E.. "Uncovering morphological interferences caused by androgen inputs in peroxisomes from primary brown trout hepatocytes using catalase immunofluorescence". Microscopy and Microanalysis 21 (2015): 71-72. http://www.scopus.com/inward/record.url?eid=2-s2.0-84944054455&partnerID=MN8TOARS.
    Published • 10.1017/S1431927615014166
  23. Pinheiro, I.; Malhão, F.; Madureira, T.V.; João Rocha, M.; Monteiro, R.A.F.; Rocha, E.. "Ethinylestradiol exposure of primary culture brown trout hepatocytes induce morphological changes in peroxisomes". Microscopy and Microanalysis 21 (2015): 81-82. http://www.scopus.com/inward/record.url?eid=2-s2.0-84944047821&partnerID=MN8TOARS.
    Published • 10.1017/S143192761501421X
  24. Madureira, T.V.; Lopes, C.; Malhão, F.; Rocha, E.. "Estimation of volume densities of hepatocytic peroxisomes in a model fish: Catalase conventional immunofluorescence versus cytochemistry for electron microscopy". Microscopy Research and Technique 78 2 (2015): 134-139. http://www.scopus.com/inward/record.url?eid=2-s2.0-84921376401&partnerID=MN8TOARS.
    Published • 10.1002/jemt.22455
  25. Madureira, T.V.; Malhão, F.; Lopes, C.; Pinheiro, I.; Gonçalves, J.F.; Rocha, E.. "Morphological alterations caused by estrogenic and anti-estrogenic signaling in peroxisomes of primary brown trout hepatocytes - Stereological approach using catalase immunofluorescence". Microscopy and Microanalysis 21 (2015): 73-74. http://www.scopus.com/inward/record.url?eid=2-s2.0-84944053257&partnerID=MN8TOARS.
    Published • 10.1017/S1431927615014178
  26. Madureira, T.V.; Malhão, F.; Pinheiro, I.; Lopes, C.; Ferreira, N.; Urbatzka, R.; Castro, L.F.C.; Rocha, E.. "Estrogenic and anti-estrogenic influences in cultured brown trout hepatocytes: Focus on the expression of some estrogen and peroxisomal related genes and linked phenotypic anchors". Aquatic Toxicology 169 (2015): 133-142. http://www.scopus.com/inward/record.url?eid=2-s2.0-84946404681&partnerID=MN8TOARS.
    Published • 10.1016/j.aquatox.2015.10.010
  27. Madureira, T.V.; Velhote, S.; Santos, C.; Cruzeiro, C.; Rocha, E.; Rocha, M.J.. "A step forward using QuEChERS (Quick, Easy, Cheap, Effective, Rugged, and Safe) based extraction and gas chromatography-tandem mass spectrometry-levels of priority polycyclic aromatic hydrocarbons in wild and commercial mussels". Environmental Science and Pollution Research 21 9 (2014): 6089-6098. http://www.scopus.com/inward/record.url?eid=2-s2.0-84899445278&partnerID=MN8TOARS.
    Published • 10.1007/s11356-014-2510-y
  28. Madureira, T.V.; Santos, C.; Velhote, S.; Cruzeiro, C.; Rocha, E.; Rocha, M.J.. "Contamination levels of polychlorinated biphenyls in wild versus cultivated samples of female and male mussels (Mytilus sp.) from the Northwest Coast of Iberian Peninsula-new application for QuEChERS (Quick, Easy, Cheap, Effective, Rugged, and Safe) methodology". Environmental Science and Pollution Research 21 2 (2014): 1528-1540. http://www.scopus.com/inward/record.url?eid=2-s2.0-84891627782&partnerID=MN8TOARS.
    Published • 10.1007/s11356-013-2017-y
  29. Couto, C.M.C.M.; Pinto, I.; Madureira, T.V.; Rocha, M.J.; Tiritan, M.E.; Lopes, J.A.; Almeida, A.A.. "Lower Douro river basin (Portugal) water quality - Focus on trace element changes and anthropogenic sources of contamination". Global Nest Journal 16 2 (2014): 252-269. https://doi.org/10.30955/gnj.001341.
    Published • 10.30955/gnj.001341
  30. Madureira, T.V.; Rocha, M.J.; Cruzeiro, C.; Rodrigues, I.; Monteiro, R.A.F.; Rocha, E.. "The toxicity potential of pharmaceuticals found in the Douro River estuary (Portugal): Evaluation of impacts on fish liver, by histopathology, stereology, vitellogenin and CYP1A immunohistochemistry, after sub-acute exposures of the zebrafish model". Environmental Toxicology and Pharmacology 34 1 (2012): 34-45. http://www.scopus.com/inward/record.url?eid=2-s2.0-84858725544&partnerID=MN8TOARS.
    Published • 10.1016/j.etap.2012.02.007
  31. Madureira, T.V.; Cruzeiro, C.; Rocha, M.J.; Rocha, E.. "The toxicity potential of pharmaceuticals found in the Douro River estuary (Portugal)-Experimental assessment using a zebrafish embryo test". Environmental Toxicology and Pharmacology 32 2 (2011): 212-217. http://www.scopus.com/inward/record.url?eid=2-s2.0-80051586550&partnerID=MN8TOARS.
    Published • 10.1016/j.etap.2011.05.005
  32. Madureira, T.V.; Rocha, M.J.; Cruzeiro, C.; Galante, M.H.; Monteiro, R.A.F.; Rocha, E.. "The toxicity potential of pharmaceuticals found in the Douro River estuary (Portugal): Assessing impacts on gonadal maturation with a histopathological and stereological study of zebrafish ovary and testis after sub-acute exposures". Aquatic Toxicology 105 3-4 (2011): 292-299. http://www.scopus.com/inward/record.url?eid=2-s2.0-79960465071&partnerID=MN8TOARS.
    Published • 10.1016/j.aquatox.2011.06.017
  33. Barreiro, J.C.; Vanzolini, K.L.; Madureira, T.V.; Tiritan, M.E.; Cass, Q.B.. "A column-switching method for quantification of the enantiomers of omeprazole in native matrices of waste and estuarine water samples". Talanta 82 1 (2010): 384-391. http://www.scopus.com/inward/record.url?eid=2-s2.0-77955417900&partnerID=MN8TOARS.
    Published • 10.1016/j.talanta.2010.04.056
  34. Madureira, T.V.; Barreiro, J.C.; Rocha, M.J.; Rocha, E.; Cass, Q.B.; Tiritan, M.E.. "Spatiotemporal distribution of pharmaceuticals in the Douro River estuary (Portugal)". Science of the Total Environment 408 22 (2010): 5513-5520. http://www.scopus.com/inward/record.url?eid=2-s2.0-77956882358&partnerID=MN8TOARS.
    Published • 10.1016/j.scitotenv.2010.07.069
  35. Madureira, T.V.; Rocha, M.J.; Cass, Q.B.; Tiritan, M.E.. "Development and optimization of a HPLC-DAD method for the determination of diverse pharmaceuticals in estuarine surface waters". Journal of Chromatographic Science 48 3 (2010): 176-182. http://www.scopus.com/inward/record.url?eid=2-s2.0-77949309353&partnerID=MN8TOARS.
    Published • 10.1093/chromsci/48.3.176
  36. Madureira, T.V.; Barreiro, J.C.; Rocha, M.J.; Cass, Q.B.; Tiritan, M.E.. "Pharmaceutical trace analysis in aqueous environmental matrices by liquid chromatography-ion trap tandem mass spectrometry". Journal of Chromatography A 1216 42 (2009): 7033-7042. http://www.scopus.com/inward/record.url?eid=2-s2.0-70349248193&partnerID=MN8TOARS.
    Published • 10.1016/j.chroma.2009.08.060
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2024/05/27 Validation and ecotoxicology applications of a 3D culture model for primary hepatocytes of brown trout 22nd Pollutant Responses in Marine Organisms
(Nantes, France)
2023/09/11 Estrogenic and statin impacts in lipid pathways of brown trout XIV Congress of the Iberian Association of Comparative Endocrinology - AIEC
(Bilbau, Spain)
2023/05/10 Can atorvastatin and 17alpha-ethinylestradiol disrupt lipid pathways in brown trout? Encontro de Investigação Jovem da U.Porto (IJUP) 2023
Universidade do Porto (Porto, Portugal)
2022/09/04 Effects of atorvastatin and 17alpha-ethinylestradiol on blood and liver lipids contents in brown trout juveniles 30th Conference of European Comparative Endocrinologists and the 9th International Conference of Fish Endocrinology
European Society for Comparative Endocrinology (ESCE) and the International Society of Fish Endocrinology (ISFE) (Faro, Portugal)
2022/09/04 Spheroids: in vitro 3D cell cultures of brown trout liver as a model for ecotoxicology research 16th Multinational Congress on Microscopy
(Brno, Czech Republic)
2018/08/19 Physiological and behavioural effects of an acute stress event in brown trout juveniles 29th Conference of European Comparative Endocrinologists
(Glasgow, United Kingdom)
2017/07/13 Silencing of PPARaBb mRNA in brown trout hepatocytes-studying the effects of ethinylestradiol and WY-14,643 XI Congress of Iberian Association for Comparative Endocrinology
(Vigo, Spain)
2017/07/13 Blood lipid profile and hepatic ultrastructural changes in brown trout (Salmo trutta f. fario) induced by hormones and hypolipidemic drugs XI Congress of Iberian Association for Comparative Endocrinology
(Vigo, Spain)
2016/06/29 How to assess expeditiously the skin dark pigmented areas in brown trout (Salmo trutta f. fario)? Developing qualitative versus quantitative approaches 50th Meeting of SPMicros - Microscopy and Microanalysis in Materials and Life Sciences
(Porto, Portugal)
2016/06/29 Optimization of a whole-mount oil red O method for lipids in brown trout larvae 50th Meeting of SPMicros - Microscopy and Microanalysis in Materials and Life Sciences
(Porto, Portugal)
2013/12/02 QuEChERS extraction and GC-MS for the analysis of polychlorinated biphenyls in wild and cultivated mussels 8th National Chromatography Meeting
(Covilhã, Portugal)
2013/05/05 Toxicological impacts of pharmaceutical mixtures in zebrafish (Danio rerio) adults and embryos – Can the reproductive success be affected by environmental levels? 17th Pollutant Responses in Marine Organisms
(Faro, Portugal)
2011/02/02 Evaluation of the toxicity of pharmaceutical compounds found in the Douro River estuary using zebrafish as an experimental model 1st Conference of the Department of Microscopy, Institute of Biomedical Sciences Abel Salazar
(Porto, Portugal)
2009/12/02 Monitoring pharmaceuticals in the Douro River estuary, Portugal 10th European Meeting on Environmental Chemistry
(Limoges, France)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2024/09/16 - Current Liraglutide effects on lipid metabolism genes and droplets in primary brown trout hepatocytes
Supervisor
 Toxicologia e Contaminação Ambientais (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2024/07/17 - Current Structural and functional effects in fish under mixtures of lipid-lowering drugs with endocrine disruptors and warming: Exploring and refining an in vivo trout model
Co-supervisor
 Ciências Biomédicas (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2023/11/09 - Current Warming and heat waves influence on modulation of PAHs and pesticides impacts in fish liver using standard and complex in vitro and ex vivo cultures
Co-supervisor
 Ciências Biomédicas (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2024/02/14 - 2024/07/28 Brown trout primary hepatocyte spheroids to test disruptions by hormones and temperature
Supervisor
 Toxicologia e Contaminação Ambientais (Other)
Universidade do Porto Faculdade de Ciências, Portugal
2024/05/27 - 2024/07 Does the sex donor fish imprint primary brown trout hepatocytes for toxicological tests?
Supervisor
 Ciências Biomédicas Laboratoriais (Other)
Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2021/09/01 - 2023/07/27 Ethinylestradiol and atorvastatin effects in liver and blood-related parameters of juvenile brown trout
Co-supervisor
 Ciências do Mar - Recursos Marinhos (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2021/09/03 - 2022/12/07 Xenoestrogenic modulation of sex-steroid related targets in brown trout primary hepatocyte spheroids
Supervisor
 Toxicologia e Contaminação Ambientais (Master)
Universidade do Porto Faculdade de Ciências, Portugal
2021/02 - 2021/06 Culture of spheroids from primary hepatocytes of brown trout for studies with xenoestrogens
Supervisor
Universidade do Porto Faculdade de Ciências, Portugal
2011 - 2021/02/09 Studies of androgenic and estrogenic effects on PPARs, estrogen receptors and some related gene and phenotypic targets, using brown trout primary hepatocytes as the model system
Co-supervisor
 Patologia e Genética Molecular (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2018/09/21 - 2019/12/17 Fish and sex steroids - Do juvenile fish have a distinct sex-specific steroid hormone profile? Observational study using the brown trout (Salmo trutta fario) as a model organism
Co-supervisor
 Ciências do Mar - Recursos Marinhos (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2018/09/13 - 2019/12/12 Xenoestrogenic and androgenic impacts on carcinogenesis onset - A mechanistically look at a controversial issue recurring to diethylnitrosamine induced carcinogenesis in zebrafish larvae
Co-supervisor
 Contaminação e Toxicologia Ambientais
Universidade do Porto Faculdade de Ciências, Portugal
2018/09/14 - 2019/11/25 Establishment of a three-dimensional (3D) in vitro model for culture of brown trout (Salmo trutta f. fario) primary hepatocyte spheroids - Insights into 5alpha-dihydrostestosterone regulation of lipid-related genes
Supervisor
 Contaminação e Toxicologia Ambientais (Master)
Universidade do Porto Faculdade de Ciências, Portugal
2017/09/13 - 2018/12/21 Characterization of brown trout fitness and gonadal maturation along a reproductive cycle
Supervisor
 Ciências do Mar - Recursos Marinhos (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2016/02 - 2018/07 Can estrogenic and lipidic-lowering agents affect lipid dynamics in brown trout larvae? - Exploring gene expression profile of target pathways
Supervisor
 Bioquímica (Degree)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2015/09/16 - 2016/12/14 Monitorização de estrogénios na água do estuário do rio Douro por SPE-ELISA
Co-supervisor
 Ciências do Mar - Recursos Marinhos (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2015/09/17 - 2016/12/12 Multiparametric evaluation of acclimatization of juvenile trout (Salmo trutta f. fario) for experimental studies
Supervisor
 Ciências do Mar - Recursos Marinhos (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2014/04 - 2014/09 Morphological and molecular study of the effects of testosterone and flutamide in primary cultures of trout hepatocytes
Supervisor
 Anatomia Patológica, Citológica e Tanatológica (Degree)
Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2011/09 - 2012/12 Development and validation of an analytical method for the detection and quantification of polychlorated biphenyls, in water and mussel samples (Mytilus sp.)
Co-supervisor
 Ciências do Mar - Recursos Marinhos (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2024/09/22 - 2024/09/22 Volunteer in CIIMAR Open Day, within the activity “Sample, smear and see the fish blood”.
Exhibition
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2024/06/05 - 2024/06/05 Design and set up a hands-on activity "The scientist comes to school - Effects caused by environmental pollutants on the behavior of brine shrimp", within the commemoration of World Environment Day, at Escola Secundária Júlio Dinis (Ovar).
Other
2024/05/26 - 2024/05/29 22nd Pollutant Responses in Marine Organisms
Congress
 22nd Pollutant Responses in Marine Organisms
2024/04/13 - 2024/04/13 Volunteer member at Mostra U.Porto 2024
Exhibition
 Mostra U.Porto
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2024/01/12 - 2024/01/12 Design and set up of the activity "Meeting with a scientist", with the theme "Ecotoxicology", at the Escola de Ciência Viva (Parque Biológico de Gaia). This activity is part of a non-formal educational project that gives students, in the fourth year of the first cycle of basic education at schools in the Municipality of Vila Nova de Gaia, practical and fun hands-on experience with science and technology.
Meeting
 Meeting with a scientist
2023/10/29 - 2023/10/29 Public engagement activity “TREC in the City” for the TREC expedition, an initiative of the European Molecular Biology Laboratory (EMBL).
Other
 TREC in the City
European Molecular Biology Laboratory, Germany
2023/09/17 - 2023/09/17 Volunteer in CIIMAR Open Day, within the activity “Water planet in danger: Learn with little brine shrimp”.
Exhibition
 Water planet in danger: Learn with little brine shrimp
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2023/09/11 - 2023/09/13 XIV Congress of the Iberian Association of Comparative Endocrinology - AIEC
Congress
 XIV Congress of the Iberian Association of Comparative Endocrinology - AIEC
2022/09/04 - 2022/09/08 30th CECE & 9th ISFE
Congress
 30th Conference of European Comparative Endocrinologists and the 9th International Conference of Fish Endocrinology
2022/05/15 - 2022/05/19 SETAC Europe 32nd Annual Meeting
Congress
 Towards a Reduced Pollution Society
2021/09/16 - 2021/09/17 XIII Congress of the Iberian Association of Comparative Endocrinology - AIEC
Congress
 XIII Congress of the Iberian Association of Comparative Endocrinology - AIEC
2021/07/05 - 2021/07/08 2021 Annual Symposium of the Fisheries Society of the British Isles
Congress
 Fish, Fisheries and Ecosystems in the Anthropocene
2021/05/03 - 2021/05/06 SETAC Europe 31st Annual Meeting
Congress
 Global Challenges. An Emergency for Environmetal Sciences
2018/09/09 - 2018/09/12 31st Congress of New European Society for Comparative Physiology and Biochemistry
Congress
 31st Congress of New European Society for Comparative Physiology and Biochemistry
2018/08/19 - 2018/08/23 29th Conference of European Comparative Endocrinologists
Congress
 29th Conference of European Comparative Endocrinologists
2018/07 - 2018/07 Junior University activity, U.Porto - Will I be a doctor, teacher, scientist or artist? Organization: Laboratory of Histology and Embryology of ICBAS (Coordination: Eduardo Rocha) and Casa Museu Abel Salazar (Coordination: Luísa Garcia Fernandes). Action for students with at least the 7th grade.
Other
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2018/02/26 - 2018/03/02 Statistics and Programming with R for Biological Sciences (20 h) - Module II: Basic Statistics
Workshop
2018/02/19 - 2018/02/23 Statistics and Programming with R for Biological Sciences (20 h) - Module I: Fundamentals of R language
Workshop
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2017/11/06 - 2017/11/10 Gulbenkian Training Programme in Bioinformatics (40 h) - Entry Level Bioinformatics
Workshop
Instituto Gulbenkian de Ciência, Portugal
2017/07/13 - 2017/07/15 XI Congress of Iberian Association for Comparative Endocrinology
Congress
 XI Congress of Iberian Association for Comparative Endocrinology
2017/07/03 - 2017/07/07 50th Anniversary Symposium of the Fisheries Society of the British Isles
Symposium
 50th Anniversary Symposium of the Fisheries Society of the British Isles
2016/06/29 - 2016/06/30 50th Meeting of SPMicros - Microscopy and Microanalysis in Materials and Life Sciences
Meeting
 50th Meeting of SPMicros - Microscopy and Microanalysis in Materials and Life Sciences
2015/07/14 - 2015/07/17 10th Iberian and 7th Iberoamerican Congress on Environmental Contamination and Toxicology
Congress
 10th Iberian and 7th Iberoamerican Congress on Environmental Contamination and Toxicology
2015/06 - 2015/06 Leadership Coaching – Continuous Education Unit (20 h)
Workshop
Universidade do Porto, Portugal
2015 - 2015 Mostra UP. The Mostra UP is an annual exhibition in which teachers, researchers, students and technicians provide information about the training offers at the University of Porto, contributing to a more informed decision to enter the university.
Exhibition
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2014/11/06 - 2014/11/07 International Conference on Microscopy and Microanalysis, XLVIII Congress of the Portuguese Microscopy Society
Congress
 International Conference on Microscopy and Microanalysis, XLVIII Congress of the Portuguese Microscopy Society
2014/08/25 - 2014/08/29 27th Conference of European Comparative Endocrinologists
Conference
 27th Conference of European Comparative Endocrinologists
2014/06 - 2014/06 Validation of Analytical Methods and Preparation of Validation Reports (24 h)
Workshop
2013/05/05 - 2013/05/08 17th International Symposium Pollutant Responses in Marine Organisms
Symposium
 17th International Symposium Pollutant Responses in Marine Organisms
2013/02 - 2013/03 An Integrative Approach to Cell Analysis: Cell and Tissue Culture, Flow Cytometry and Microscopy Life and Health Sciences Research Institute (40 h)
Workshop
Universidade do Minho, Portugal
2011/12 - 2011/12 Laboratory Animals Sciences - Aquatic Organisms (CAL-AQUA) – Aquatic Organisms Bioterium (BOGA) (41 h)
Workshop
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2011/09 - 2011/09 Practical Approach to Ecotoxicogenomics - Advanced Workshop Studies in Biology and Applied Biosciences (40 h)
Workshop
Universidade de Aveiro Centro de Estudos do Ambiente e do Mar, Portugal
2011/06 - 2011/07 Statistical Applied to Science – Module I: Introduction to statistical analysis; Module II: Statistical methods for population comparison and Module III: Multivariate statistical analysis (60 h)
Workshop
Universidade de Aveiro Departamento de Matemática, Portugal
2011/05/15 - 2011/05/19 21th Annual Meeting of the Society of Environmental Toxicology and Chemistry Europe
Meeting
 21th Annual Meeting of the Society of Environmental Toxicology and Chemistry Europe
2010/05/23 - 2010/05/27 20th Annual Meeting of the Society of Environmental Toxicology and Chemistry Europe
Meeting
 20th Annual Meeting of the Society of Environmental Toxicology and Chemistry Europe
2010/05 - 2010/05 How to Best Conduct Aquatic Ecotoxicity Tests according to the International Guidelines
Workshop
 20th Annual Meeting of the Society of Environmental Toxicology and Chemistry Europe - - Science and Technology for Environmental Protection
2009/10/17 - 2009/10/22 17th Meeting of the Brazilian Chemical Society - Regional Interior Paulista Waldemar Saffioti,
Meeting
 17th Meeting of the Brazilian Chemical Society - Regional Interior Paulista Waldemar Saffioti,
2009/06/28 - 2009/07/02 34th International Symposium on High Performance Liquid Phase Separations and Related Techniques
Symposium
 34th International Symposium on High Performance Liquid Phase Separations and Related Techniques
2009/06 - 2009/06 Principles and Applications of LC-MS
Workshop
 34th International Symposium on High Performance Liquid Phase Separations and Related Techniques
2008/10/28 - 2008/10/30 XII Latin American Congress of Chromatography and Related Techniques
Congress
 XII Latin American Congress of Chromatography and Related Techniques
2008/03 - 2008/07 Development of Methods by HPLC: Fundamentals, Strategies and Validation
Other
Universidade Federal de São Carlos Departamento de Química, Brazil
2008/05/10 - 2008/05/16 32nd International Symposium on High Performance Liquid Phase Separations and Related Techniques
Symposium
 32nd International Symposium on High Performance Liquid Phase Separations and Related Techniques

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2022/12/07 Xenoestrogenic modulation of sex-steroid related targets in brown trout primary hepatocyte spheroids
Supervisor
 Rodrigo Franco Alves (Master)
Universidade do Porto Faculdade de Ciências, Portugal
2021/10/08 Stereological estimation of oocyte volumes with the nucleator after sampling with conventional versus modified (single-section) disectors - Does it work?
(Thesis) Main arguer
 Paula Costa (Other)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2020/06/19 From genes to nutrition: lipid metabolism in the Brazilian teleost tambaqui (Colossoma macropomum)
(Thesis) Arguer
 Renato Barbosa Ferraz (PhD)
Universidade do Porto, Portugal
2019/11/25 Establishment of a three-dimensional (3D) in vitro model for culture of brown trout (Salmo trutta f. fario) primary hepatocyte spheroids - Insights into 5alpha-dihydrostestosterone regulation of lipid-related genes
Supervisor
 Inês Lopes Pereira (Master)
Universidade do Porto Faculdade de Ciências, Portugal
2018/12/21 Characterization of brown trout fitness and gonadal maturation along a reproductive cycle
Supervisor
 Diana Santiago dos Santos (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2018/12/21 Effects of mixtures of oestrogenic and progestagenic contraceptive pills ingredients on fish reproduction and gonadogenesis - An experimental study on zebrafish
(Thesis) Main arguer
 Rodolfo Miguel Almeida Silva (Other)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2018/12/12 Determination and risk evaluation of PAHs and PCBs in seawater samples collected at north and south of the Vila do Conde ornithological reserve
(Thesis) Main arguer
 Ana Beatriz Teixeira Ribeiro (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2018/07/31 Avaliação imunohistoquímica dos efeitos combinados da exposição à progestina levonorgestrel e aumento da temperatura no funcionamento do fígado de peixe-zebra
(Thesis) Main arguer
 Ricardo Luís Resende de Oliveira (Other)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2018/07 Can estrogenic and lipidic-lowering agents affect lipid dynamics in brown trout larvae? - Exploring gene expression profile of target pathways
Supervisor
 Inês Maria da Mota (Other)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2017/06 Protective effect of resveratrol and quercetin on tamoxifen and imatinib induced hepatotoxicity
(Thesis) Main arguer
 Raquel Sofia Remoaldo Vaz (Other)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2016/12/12 Multiparametric evaluation of acclimatization of juvenile trout (Salmo trutta f. fario) for experimental studies
Supervisor
 Joana Luísa Costa (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2016/07 Combined effects of warming, acidification and the synthetic progestin levonorgestrel on the fitness of the marine amphipod Gammarus locusta (Crustacea)
(Thesis) Main arguer
 Epeli Manu Loganimoce (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2016/05 Enlightening the complex sex determination and differentiation of zebrafish (Danio rerio)
(Thesis) Main arguer
 Ana Catarina Gonçalves Luzio (PhD)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2015/06 Climate change and coastal diversity
(Thesis) Main arguer
 Maria Cristina Ruiz Pena (Other)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2014/10 Removal of fluoroquinolones: Biosorption in activated sludge and aerobic granular sludge
(Thesis) Main arguer
 Vanessa Regina Azevedo Ferreira (Master)
Universidade do Porto Faculdade de Farmácia, Portugal

Committee member

Activity description
Role 		Institution / Organization
2024/06/01 - Current Member of the Program Follow-up Committee of the Master Degree in Marine Sciences - Marine Resources, ICBAS - U.Porto
Member
 Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Distinctions

Award

2009 Scholarship for participation in the 34th International Symposium on High Performance Liquid Phase Separations and Related Techniques, Dresden (Germany)
Iowa State University, United States
2006 Lusitana Pharmaceutical Society Award
2006 Award for best student of the Pharmaceutical Sciences Degree (2004-2005)