???global.info.a_carregar???
Maria Inês Pimentel Mendes. Investigadora no Centro de Química da Universidade de Coimbra. Estudante de Doutoramento no Programa Doutoral MedChemTrain na área da Tomografia Fotoacústica.
Identification

Personal identification

Full name
Maria Inês Pimentel Mendes

Citation names

  • Maria Inês P. Mendes
  • Maria Ines P. Mendes
  • Maria Mendes

Author identifiers

Ciência ID
3311-CFA3-A16E
ORCID iD
0000-0003-0683-6717

Email addresses

  • mariainesmendes9@gmail.com (Professional)

Addresses

  • Rua Larga, Departamento de Química, 3004-535, Coimbra, Coimbra, Portugal (Professional)

Knowledge fields

  • Exact Sciences - Chemical Sciences - Physical Chemistry

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Education
Degree Classification
2017/11 - 2021/11
Ongoing
 Química (Doutoramento)
Major in Química Médica - MedChem Train
Universidade de Lisboa Faculdade de Farmácia, Portugal

Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Photoacoustic Imaging and Delivery" (THESIS/DISSERTATION)
2015/09 - 2017/09
Concluded
 Química Medicinal (Mestrado)
Universidade de Coimbra, Portugal
"Identification of glycolysis inhibitors with potentiating effect on photodynamic therapy in vitro" (THESIS/DISSERTATION)
 18/20
2012/09 - 2015/07
Concluded
 Química Medicinal (Licenciatura)
Universidade de Coimbra, Portugal
 15/20
Affiliation

Others

Category
Host institution 		Employer
2022/06/15 - Current Investigador LaserLeap Technologies, Portugal
2017/11 - Current Doutoramento no Programa MedChem Train - "Photoacoustic Imaging and Delivery" Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
(...)
2020/01/08 - 2020/03/18 Bolsa Fulbright para Investigação com o apoio da FCT - Síntese Orgânica Louisiana State University Department of Chemistry, United States
2018/05 - 2018/06 Rotação Laboratorial com Luis G Arnaut - "LUZ51B: A Biodistribution Study in C57BL/6J mice" - Experimentação Animal Universidade de Coimbra Centro de Química de Coimbra, Portugal
2018/04 - 2018/05 Rotação Laboratorial com Pedro Gois - "Synthesis of boronated phenylalanine derivatives for PAH rescue" - Síntese Orgânica Universidade de Lisboa Faculdade de Farmácia, Portugal
2018/03 - 2018/04 Rotação Laboratorial com Alexandra Antunes - "The role of tolvaptan bioactivation in the onset of hepatotoxic events" - Espectrometria de Massa Universidade de Lisboa Instituto Superior Técnico, Portugal
2016/09 - 2017/09 Tese de Mestrado com Luis G Arnaut - "Identification of glycolysis inhibitors with potentiating effect on photodynamic therapy in vitro" - Técnicas de Cultura Celular Universidade de Coimbra Centro de Química de Coimbra, Portugal
2016/06 - 2016/07 Rotação Laboratorial com Ana Paula Martins - "The impact of methamphetamine on astrocytes" - Cultura de células primárias e imortalizadas; Experimentação Animal CNC.IBILI, Portugal
2015/02 - 2015/07 Estágio de Licenciatura com Luis G Arnaut - "Analysis of profundity of necrosis with frontal and interstitial irradiation in PDT" - Experimentação Animal, Histologia Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2014/09 - 2014/09 Estágio de verão com Teresa Pinho Melo - "Synthesis of new hexacyclic steroids via [8p + 2p] cycloaddition" - Síntese Orgânica Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
Projects

Contract

Designation Funders
2022/01/17 - 2025/01/16 Como administrar macromoléculas a células-alvo e ativar terapias para o cancro: Deliver-Detect-Defeat (DDD) Deliver-Detect-Defeat (DDD): How to place macromolecules in target cells and make therapies work
PTDC/QUI-OUT/0303/2021
PhD Student Fellow
Outputs

Publications

Conference paper
  1. Arnaut, Luis G.; Catarina S. Lobo; Maria Inês P. Mendes; Diogo A. C. F. Pereira. "Photoacoustic delivery and imaging methods in PDT". Paper presented in Proc. SPIE, 2022.
    10.1117/12.2609789
Journal article
  1. Bernardo A. Nogueira; Nélia C.T. Tavares; Maria Inês P. Mendes; Diogo A. Pereira; Amílcar Duque-Prata; Fábio Schaberle. "A Preuniversity Initiative to Motivate Students to Pursue Chemistry Higher Education". Journal of Chemical Education (2023): http://dx.doi.org/10.1021/acs.jchemed.2c01095.
    10.1021/acs.jchemed.2c01095
  2. Maria Inês P. Mendes; Schaberle, FA; Maria João Moreno; Calvete, Mário J. F. ; Arnaut, Luis G.. "Photoacoustics of nanodroplet vaporization with pulsed-laser excitation of fluorinated porphyrins". Photoacoustics (2023):
    Submitted
  3. Lobo, Ana Catarina S. ; Maria Inês P. Mendes; Diogo A. Pereira; Lígia C. Gomes-da-Silva; Arnaut, Luis G.. "Photodynamic Therapy Changes Immunogenicity, Promotes Immune-Checkpoint Blockade Response, but Penetration-Resistant Tumors Require Micromechanical Tumor Priming". Scientific Reports (2023):
    Under revision
  4. Maria Inês P. Mendes; Luis G. Arnaut. "Redaporfin Development for Photodynamic Therapy and its Combination with Glycolysis Inhibitors". Photochemistry and Photobiology (2022): https://doi.org/10.1111/php.13770.
    10.1111/php.13770
  5. Nogueira, Bernardo A.; Silva, Alexandre D.; Mendes, Maria Inês P.; Pontinha, Ana Dora R.; Serpa, Carlos; Calvete, Mário J. F.; Rocha-Gonçalves, Alexandra; Caridade, Pedro J. B. S.; Rodrigues, Sérgio P. J.. "Molecular School - a pre-university chemistry school". Chemistry Teacher International 0 0 (2021): 1-12. http://dx.doi.org/10.1515/cti-2020-0013.
    Published • 10.1515/cti-2020-0013
  6. Filipa Ramilo-Gomes; João P. M. António; Maria Inês P. Mendes; Rafael F. A. Gomes. "MedChemTrain e-School 2020: Event Highlights and Insights into Virtual Symposium Organization". ChemMedChem 15 24 (2020): 2562-2568. https://doi.org/10.1002%2Fcmdc.202000450.
    Published • 10.1002/cmdc.202000450
  7. Rocha, Luís B.; Helder T. Soares; Maria Inês P. Mendes; Cabrita, António; Schaberle, FA; Arnaut, Luis G.. "Necrosis depth and photodynamic threshold dose with redaporfin-PDT". Photochemistry and Photobiology (2020): http://dx.doi.org/10.1111/php.13256.
    10.1111/php.13256

Intellectual property

Patent
  1. Arnaut, Luis G.; Maria Inês P. Mendes; Diogo A. C. F. Pereira; Carlos A. L. Serpa Soares; Celso M. F. P. João; João P. F. B. C. Santos. 2022. "Devices and methods for priming solid tumors with pressure pulses to enhance anticancer therapies".
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2022/06/20 Nanodroplets loaded with Tetrapyrrolic Dyes for Photoacoustic Tomography ICPPP21 International Conference on Photoacoustic and Photothermal Phenomena
(Bled, Slovenia)
2022/06/02 Photoacoustic Imaging and Delivery Invited Talk for IEEE-SB-UC Student Association
2022/04/09 Can Photodynamic Therapy efficacy be increased with Photoacoustic delivery of the Photosensitizer? VIII Encontro Nacional de Estudantes de Química
(Coimbra , Portugal)
2021/10/19 Phthalocyanine loaded nanodroplets for Photoacoustic Tomography International School of Quantum Electronics 64th Course – Progress in Photoacoustic & Photothermal Phenomena. Focus on Biomedical, Nanoscale, NDE, Gas Sensing and Thermophysical Phenomena ad Technologies
(Erice, Italy)
2021/03/27 Porphyrin loaded nanodroplets for Photoacoustic Tomography Colóquio Digital de Estudantes de Química em Portugal
(Portugal)
2019/11/21 Phthalocyanine loaded nanodroplets for Photoacoustic Tomography XXV Encontro Galego-Portugues de Química
(Santiago de Compostela, Spain)
2017/04/08 The impact of cellular metabolism in Photodynamic Therapy with Redaporfin V ENEQUI (V Encontro Nacional de Estudantes de Química)
(Coimbra, Portugal)
2016/11/17 The effect of 2-deoxyglucose on photodynamic therapy with redaporfin IIECNEQAAC (II Encontro Científico do NEQ/AAC)
(Coimbra, Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2022/01 - 2022/09 Photoacoustic study of porphyrin-loaded nanodroplets
Co-supervisor
2021/01 - 2021/09 Agentes de Contraste para Imagiologia Fotoacústica
Co-supervisor

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2022/01/01 - 2022/04/10 VIII ENEQUI (Encontro Nacional de Estudantes de Química) - Comissão Organizadora de um evento que contou com a presença do Prémio Nobel da Química Sir Fraser Stoddart. (2022/04/08 - 2022/04/10)
Meeting (Member of the Organising Committee)
2021/03/01 - 2021/06/12 3º edição da Escola Molecular - Escola Pré-Universitária de Química, Coimbra, 2021 (2021/05/01 - 2021/06/12)
Other (Co-organisor)
2020/04/27 - 2020/04/29 MedChemTrain e-School: Evento virtual que teve a participação de mais de 1400 inscritos. Contou com 5 apresentações orais de Investigadores internacionais de diversas áreas da Química e 2 mesas redondas: "What can I do with my PhD? The next step", reunindo jovens cientistas que desempenham diversas funções na indústria ou academia; "Academia, Industry and Coronavirus - Challenges and Opportunities", reunindo responsáveis de diversas industrias farmacêuticas (Hovione, Bluepharma, Novartis) e investigadores de renome portugueses e internacionais. (2020/04/27 - 2020/04/29)
Conference (Co-organisor)
2019/01/01 - 2019/04/27 1º edição da Escola Molecular - Escola Pré-Universitária de Química, Coimbra, 2021 (2019/03/02 - 2019/04/27)
Other (Co-organisor)
2017/05/01 - 2017/06/13 Comissão organizadora do "16th International Photodynamic Association World Congress - IPA 2017" (2017/06/08 - 2017/06/13)
Congress (Member of the Organising Committee)

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2019/07/01 - 2019/07/01 Poster: Can glycolysis inhibitors potentiate photodynamic therapy?
Congress
 17th International Photodynamic Association World Congress (IPA)
2017/07/17 - 2017/07/17 Poster: Can inhibition of glycolysis increase the selectivity of photodynamic therapy towards cancer cells?
Congress
 XXV Encontro Nacional da SPQ
2017/06/10 - 2017/06/10 Poster: "The impact of glycolysis inhibitors in photodynamic therapy with redapofin"
Congress
 16th International Photodynamic Association World Congress - IPA 2017
2016/11/10 - 2016/11/10 Poster: The effect of 2-deoxyglucose on Photodynamic therapy with Redaporfin
Congress
 XXII Encontro Luso-Galego de Química
2016/05 - 2016/05 Curso de Experimentação Animal - XXI Edition of the Laboratory Animal Science Course – i3S - FELASA credited Category C course
Other
 XXI Edition of the Laboratory Animal Science Course – i3S
2013/09 - 2014/01 Curso de Inglês -Faculdade de Letras da Universidade de Coimbra - Nível B2

Association member

Society Organization name Role
2018/09 - 2021/11/01 Molecular Junior Enterprise Membro da equipa da Molecular JE - Promoção da Química junto de alunos do ensino básico e secundário
2013/09 - 2017/05 Núcleo de Estudantes de Química da Associação Académica de Coimbra Colaboradora (13/14), Coordenadora do Pelouro de intervenção Cívica e Ambiente(14/15 e 15/16) e Vice-Presidente da Mesa do Plenário (16/17)

Committee member

Activity description
Role 		Institution / Organization
2021/11/11 - 2021/11/13 Membro da Comissão Científica do Encontro Científico do NEQ/AAC
Member
Distinctions

Award

2022 Melhor Apresentação Oral no VIII Encontro de Estudantes de Química