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Teresa Laura Mendes Serafim. Concluiu o(a) Doutoramento em Biociências em 2011 pelo(a) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Doutoramento em Toxicology em 2011 pelo(a) Universidade de Coimbra Faculdade de Ciencias e Tecnologia e Licenciatura em Biology em 2004 pelo(a) Universidade de Évora. É Investigador Contratado no(a) Instituto de Medicina Molecular. Recebeu 4 prémio(s) e/ou homenagens.
Identification

Personal identification

Full name
Teresa Laura Mendes Serafim

Citation names

  • Serafim, Teresa
  • T. L. Serafim

Author identifiers

Ciência ID
3314-0E2E-710B
ORCID iD
0000-0003-4924-5204
Google Scholar ID
Teresa Serafim
Researcher Id
A-2119-2012
Scopus Author Id
15133224300

Knowledge fields

  • Natural sciences - Biological Sciences - Cell Biology
  • Medical and Health Sciences - Basic Medicine - Toxicology
  • Medical and Health Sciences - Clinical Medicine - Oncology

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
French Intermediate (B1) Advanced (C1) Intermediate (B1) Intermediate (B1)
Italian Intermediate (B1) Advanced (C1) Intermediate (B1) Intermediate (B1)
Spanish; Castilian Intermediate (B1) Advanced (C1) Intermediate (B1) Intermediate (B1)
Education
Degree Classification
2011
Concluded
 Biociências (Doutoramento)
Major in Especialidade: Toxicologia
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal

University of Minnesota Medical School - Duluth Campus, United States

Mercer University - Savannah Campus, United States
"Mitochondria and Cancer: Opening Pandora´s Box" (THESIS/DISSERTATION)
 Approved with praise and distinction by unanimity
2004
Concluded
 Biology (Licenciatura)
Universidade de Évora, Portugal
"As Fosfatases e a Cascata Apoptotica na Doença de Alzheimer" (THESIS/DISSERTATION)
 15 valores
Affiliation

Science

Category
Host institution 		Employer
2018/12/19 - Current Contracted Researcher (Research) Instituto de Medicina Molecular, Portugal
2015/11/01 - 2018/11/30 Postdoc (Research) Instituto de Medicina Molecular, Portugal
2012/02/01 - 2015/10/31 Postdoc (Research) CNC.IBILI, Portugal
2006/07/01 - 2007/08/31 Research Trainee (Research) University of Minnesota Medical School - Duluth Campus, United States
2005/08/01 - 2006/06/30 Research Trainee (Research) CNC.IBILI, Portugal
Projects

Contract

Designation Funders
2018/12 - Current How does cholesterol promote breast cancer metastasis (lipidmets).
PTDC/SAU-ONC/114080/2017
Post-doc
Instituto de Medicina Molecular, Portugal
Ongoing
2015/11 - 2018/12 IL-7/IL-7R signaling networks in health and malignancy
ERC CoG-648455
Post-doc
European Research Council
2013/05 - 2015/04 Pathophysiology of Persistent Doxorubicin Cardiotoxicity: a Mitochondrial-Epigenetics Link
126115
Provided by PTCRIS: 126115
Post-doc
Fundação para a Ciência e a Tecnologia, I.P.
Concluded
2011/03 - 2014/08 Protective Activity of SIRT3 Against Drug-induced Mitochondrial Dysfunction
Provided by PTCRIS: 110952
110952
Post-doc Fellow
Fundação para a Ciência e a Tecnologia, I.P.
Concluded
2010/04 - 2013/03 Opening Pandora's Box for Active Anti-Breast Cancer Therapy - The Role of Selective Targeting to Mitochondria
Provided by PTCRIS: 101409
101409
PhD Student Fellow
Fundação para a Ciência e a Tecnologia, I.P.
Concluded
2009/01 - 2012/06 Anticancer Activity of Novel Polyamine Pd(II) Complexes - A Multidisciplinary Study
66701
Provided by PTCRIS: 66701
PhD Student Fellow
Fundação para a Ciência e a Tecnologia, I.P.
Concluded
2005/10 - 2009/04 Development of New Anticancer Agents: Phenolic Derivatives of Natural or Synthetic Origin - Structure-Activity Relationships
55631
Provided by PTCRIS: 55631
Researcher
Fundação para a Ciência e a Tecnologia, I.P.
Concluded
Outputs

Publications

Book
  1. Serafim, T.L.; Milhazes, N.; Borges, F.; Oliveira, P.J.. Caffeic and Ferulic Acid Derivatives: Use in Breast Cancer. 2014.
  2. Serafim, Teresa. Conhecer para Proteger. Aveiro, Portugal. 2005.
    Published
Book chapter
  1. Serafim, Teresa. "Caffeic and Ferulic Acid Derivatives: Use in Breast Cancer". 2014.
    10.1016/B978-0-12-409517-5.00074-7
  2. Serafim, Teresa. "Regulating Mitochondrial Respiration in Cancer". 2014.
    10.1007/978-1-4614-9545-1_3
  3. Serafim, Teresa. "Analysis of Pro-apoptotic Protein Trafficking to and from Mitochondria". 2014.
    10.1007/978-1-4939-1875-1_14
Journal article
  1. Teresa L. Serafim; Teresa Cunha-Oliveira; Claudia M. Deus; Vilma A. Sardão; Ines M. Cardoso; Shanshan Yang; John F. Odhiambo; et al. "Maternal obesity in sheep impairs foetal hepatic mitochondrial respiratory chain capacity". European Journal of Clinical Investigation (2021): https://doi.org/10.1111/eci.13375.
    10.1111/eci.13375
  2. Ferreira, Leonardo M.R.; Li, Albert M.; Serafim, Teresa L.; Sobral, Margarida C.; Alpoim, M. Carmen; Urbano, Ana M.. "Intermediary metabolism: An intricate network at the crossroads of cell fate and function". Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease (2020): 165887. http://dx.doi.org/10.1016/j.bbadis.2020.165887.
    10.1016/j.bbadis.2020.165887
  3. Bajzikova, Martina; Kovarova, Jaromira; Coelho, Ana R.; Boukalova, Stepana; Oh, Sehyun; Rohlenova, Katerina; Svec, David; et al. "Reactivation of Dihydroorotate Dehydrogenase-Driven Pyrimidine Biosynthesis Restores Tumor Growth of Respiration-Deficient Cancer Cells". Cell Metabolism (2018): http://dx.doi.org/10.1016/j.cmet.2018.10.014.
    10.1016/j.cmet.2018.10.014
  4. Pereira, S.P.; Deus, C.M.; Serafim, T.L.; Cunha-Oliveira, T.; Oliveira, P.J.. "Metabolic and phenotypic characterization of human skin fibroblasts after forcing oxidative capacity". Toxicological Sciences 164 1 (2018): 191-204. http://www.scopus.com/inward/record.url?eid=2-s2.0-85050824332&partnerID=MN8TOARS.
    10.1093/toxsci/kfy068
  5. Carvalho, F.S.; Morais, C.M.; Holy, J.; Krasutsky, D.; Yemets, S.V.; Krasutsky, P.A.; Jurado, A.S.; Oliveira, P.J.; Serafim, T.L.. "Toxicity of lupane derivatives on anionic membrane models, isolated rat mitochondria and selected human cell lines: Role of terminal alkyl chains". Chemico-Biological Interactions 296 (2018): 198-210. http://www.scopus.com/inward/record.url?eid=2-s2.0-85054805798&partnerID=MN8TOARS.
    10.1016/j.cbi.2018.10.002
  6. Teixeira, J.; Amorim, R.; Santos, K.; Soares, P.; Datta, S.; Cortopassi, G.A.; Serafim, T.L.; et al. "Disruption of mitochondrial function as mechanism for anti-cancer activity of a novel mitochondriotropic menadione derivative". Toxicology 393 (2018): 123-139. http://www.scopus.com/inward/record.url?eid=2-s2.0-85034013034&partnerID=MN8TOARS.
    10.1016/j.tox.2017.11.014
  7. Coelho, Ana R.; Martins, Tatiana R.; Couto, Renata; Deus, Cláudia; Pereira, Cláudia V.; Simões, Rui F.; Rizvanov, Albert A.; et al. "Berberine-induced cardioprotection and Sirt3 modulation in doxorubicin-treated H9c2 cardiomyoblasts". Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1863 11 (2017): 2904-2923. http://dx.doi.org/10.1016/j.bbadis.2017.07.030.
    10.1016/j.bbadis.2017.07.030
  8. Gonçalves, A.M.M.; Barroso, D.V.; Serafim, T.L.; Verdelhos, T.; Marques, J.C.; Gonçalves, F.. "The biochemical response of two commercial bivalve species to exposure to strong salinity changes illustrated by selected biomarkers". Ecological Indicators 77 (2017): 59-66. http://www.scopus.com/inward/record.url?eid=2-s2.0-85012862794&partnerID=MN8TOARS.
    10.1016/j.ecolind.2017.01.020
  9. Deus, C.M.; Serafim, T.L.; Magalhães-Novais, S.; Vilaça, A.; Moreira, A.C.; Sardão, V.A.; Cardoso, S.M.; Oliveira, P.J.. "Sirtuin 1-dependent resveratrol cytotoxicity and pro-differentiation activity on breast cancer cells". Archives of Toxicology 91 3 (2017): 1261-1278. http://www.scopus.com/inward/record.url?eid=2-s2.0-84976428138&partnerID=MN8TOARS.
    10.1007/s00204-016-1784-x
  10. Oliveira, M.L.; Akkapeddi, P.; Alcobia, I.; Almeida, A.R.; Cardoso, B.A.; Fragoso, R.; Serafim, T.L.; Barata, J.T.. "From the outside, from within: Biological and therapeutic relevance of signal transduction in T-cell acute lymphoblastic leukemia". Cellular Signalling 38 (2017): 10-25. http://www.scopus.com/inward/record.url?eid=2-s2.0-85021247666&partnerID=MN8TOARS.
    10.1016/j.cellsig.2017.06.011
  11. Serafim, Teresa. "Cardiomyocyte H9c2 cells present a valuable alternative to fish lethal testing for azoxystrobin". Environmental Pollution (2015):
    10.1016/j.envpol.2015.08.026
  12. Ferreira, André; Serafim, Teresa L.; Sardão, Vilma A.; Cunha-Oliveira, Teresa. "Role of mtDNA-related mitoepigenetic phenomena in cancer". European Journal of Clinical Investigation 45 (2014): 44-49. http://dx.doi.org/10.1111/eci.12359.
    10.1111/eci.12359
  13. Serafim, Teresa L.; Carvalho, Filipa S.; Bernardo, Telma C.; Pereira, Gonçalo C.; Perkins, Edward; Holy, Jon; Krasutsky, Dmytro A.; et al. "New derivatives of lupane triterpenoids disturb breast cancer mitochondria and induce cell death". Bioorganic & Medicinal Chemistry 22 21 (2014): 6270-6287. http://dx.doi.org/10.1016/j.bmc.2014.08.013.
    10.1016/j.bmc.2014.08.013
  14. Serafim, Teresa. "Targeting mitochondrial function for the treatment of breast cancer". Future Medicinal Chemistry (2014): http://www.future-science.com/loi/fmc.
    10.4155/FMC.14.100
  15. Deus, C.M.; Coelho, A.R.; Serafim, T.L.; Oliveira, P.J.. "Targeting mitochondrial function for the treatment of breast cancer". Future Medicinal Chemistry 6 13 (2014): 1499-1513. http://www.scopus.com/inward/record.url?eid=2-s2.0-84908603766&partnerID=MN8TOARS.
    10.4155/fmc.14.100
  16. Bernardo, T.C.; Cunha-Oliveira, T.; Serafim, T.L.; Holy, J.; Krasutsky, D.; Kolomitsyna, O.; Krasutsky, P.; Moreno, A.M.; Oliveira, P.J.. "Dimethylaminopyridine derivatives of lupane triterpenoids cause mitochondrial disruption and induce the permeability transition". Bioorganic and Medicinal Chemistry 21 23 (2013): 7239-7249. http://www.scopus.com/inward/record.url?eid=2-s2.0-84886951814&partnerID=MN8TOARS.
    10.1016/j.bmc.2013.09.066
  17. Serafim, Teresa L.; Carvalho, Filipa S.; Marques, Maria P. M.; Calheiros, Rita; Silva, Tiago; Garrido, Jorge; Milhazes, Nuno; et al. "Lipophilic Caffeic and Ferulic Acid Derivatives Presenting Cytotoxicity against Human Breast Cancer Cells". Chemical Research in Toxicology 24 5 (2011): 763-774. http://dx.doi.org/10.1021/tx200126r.
    10.1021/tx200126r
  18. Diogo, C. V.; Machado, N. G.; Barbosa, I. A.; Serafim, T. L.; Burgeiro, A.; Oliveira, P. J.. "Berberine as a Promising Safe Anti-Cancer Agent - Is there a Role for Mitochondria?". Current Drug Targets 12 6 (2011): 850-859.
  19. Diogo, C.V.; Machado, N.G.; Barbosa, I.A.; Serafim, T.L.; Burgeiro, A.; Oliveira, P.J.. "Berberine as a promising safe anti-cancer agent - is there a role for mitochondria?". Current Drug Targets 12 6 (2011): 850-859. http://www.scopus.com/inward/record.url?eid=2-s2.0-79955619830&partnerID=MN8TOARS.
    10.2174/138945011795528930
  20. Serafim, Teresa L.; Matos, Júlio A.C.; Sardão, Vilma A.; Pereira, Gonçalo C.; Branco, Ana F.; Pereira, Sandro L.; Parke, Donna; et al. "Sanguinarine cytotoxicity on mouse melanoma K1735-M2 cells—Nuclear vs. mitochondrial effects". Biochemical Pharmacology 76 11 (2008): 1459-1475. http://dx.doi.org/10.1016/j.bcp.2008.07.013.
    10.1016/j.bcp.2008.07.013
  21. Pereira, G. C.; Branco, A. F.; Matos, J. A. C.; Pereira, S. L.; Parke, D.; Perkins, E. L.; Serafim, T. L.; et al. "Mitochondrially Targeted Effects of Berberine [Natural Yellow 18, 5,6-dihydro-9,10-dimethoxybenzo(g)-1,3-benzodioxolo(5,6-a) quinolizinium] on K1735-M2 Mouse Melanoma Cells: Comparison with Direct Effects on Isolated Mitochondrial Fractions". Journal of Pharmacology and Experimental Therapeutics 323 2 (2007): 636-649. http://dx.doi.org/10.1124/jpet.107.128017.
    10.1124/jpet.107.128017
  22. Serafim, Teresa L.; Oliveira, Paulo J.; Sardao, Vilma A.; Perkins, Ed; Parke, Donna; Holy, Jon. "Different concentrations of berberine result in distinct cellular localization patterns and cell cycle effects in a melanoma cell line". Cancer Chemotherapy and Pharmacology 61 6 (2007): 1007-1018. http://dx.doi.org/10.1007/s00280-007-0558-9.
    10.1007/s00280-007-0558-9
  23. Moreno, A. J. M.; Serafim, T. L.; Oliveira, P. J.; Madeira, V. M. C.. "Inhibition of mitochondrial bioenergetics by carbaryl is only evident for higher concentrations - Relevance for carbaryl toxicity mechanisms". Chemosphere 66 3 (2007): 404-411.
    10.1016/j.chemosphere.2006.06.030
Thesis / Dissertation
  1. Oliveira, Paulo Jorge; Marques, Maria Paula. "Mitochondria and Cancer: Opening Pandora's Box". PhD, 2011. http://hdl.handle.net/10316/17956.
  2. Serafim, Teresa. "Phosphatases and Apoptotic Cascade in Alzheimer´s Disease". Degree, Universidade de Aveiro, 2004.

Other

Other output
  1. Antioxidant and Antimicrobial Activities of Arylamide-Acetals derivates: Potential Drugs for Neurodegenerative Diseases. Antioxidants behave as major defense agents against reactive oxygen species (ROS) which are prominent in many serious illnesses, including neurodegenerative diseases such as: Alzheimer’s and Parkinson’s diseases [1]. It is thought that some of the symptoms are due to the imbalance between pro-oxidant and antioxidant homeostasis. Antioxidant defense mechanisms are responsible for the removal of O2,. 2014. Oliveira, P.; Ambrósio, F.; Laranjinha, J.; Oliveira, T.; Serafim, T.; Sardão, V.. http://hdl.handle.net/10174/13091.
  2. Chemical characterization and antimicrobial properties of essential oils of five aromatic herbs from Alentejo flora. Aromatic plants, an important source of biologically active products, have been used for a variety of purposes for thousands of years and are recognized by their antibacterial, antifungal, antiviral, insecticidal, and antioxidant properties. The use of essential oils (EOs) are increasingly alongside in traditional medicine. Alentejo (southeast of Portugal) is a Mediterranean region rich in aromati. 2014. Oliveira, P.; Ambrósio, F.; Vega-Naredo, I.; Laranjinha, J.; Oliveira, T.; Serafim, T.; Sardão, V.. http://hdl.handle.net/10174/12913.
  3. Mitochondria as a target for novel chemotherapeutic agents based on phenolic acids. Every day, new molecules with antineoplastic potentialare discovered. Unfortunately, most of these moleculeslack cell-type specificity, and are unable to kill tumorcells any more efficiently than normal cells. Also, a highnumber of those molecules are very toxic. In order todesign more effective chemotherapeutic drugs, it is importantto understand the interaction between novelmolecules and biologi. 2010. Faculdade de Ciências. http://hdl.handle.net/10216/93603.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2019/09/01 Metabolic reprograming of pulmonary metastasis Oncometabolism: From Conceptual Knowledge to Clinical Applications
Luso, Portugal
2018/10/23 Mitochondria and Cancer
CEDOC - CHRONIC DISEASES FCM NOVA (Lisboa, Portugal)
2018/04/05 IL-7/IL-7R signaling and T cell leukemia - Chemical Screening ReTuBi - Cancer Biology
(Baião, Portugal)
2016/03/16 Maternal Obesity (MO) in Sheep Decreases Fetal Hepatic Mitochondrial Respiratory Chain Activity 63rd Annual Scientific Meeting of Society for Reproductive Investigation
Society for Reproductive Investigation (Montreal, Canada)
2015/02/02 Mitochondrial characterization of human breast cancer cell lines for in vitro cancer research. Cancer Epigenetics and Metabolism: Connecting the Dots
Biocant (Cantanhede, Portugal)
2011/09/27 Lipophilic derivatives of cinnamic and hydrocinnamic acids. Design, synthesis and antiproliferative activities. Conferência CEF 2011
University of Coimbra (Coimbra, Portugal)
2008/12/20 Different concentrations of berberine result in distinct cellular localization patterns and cell cycle effects in a melanoma cell line. Annual Meeting of Center for Neurosciences and Cell Biology
Center for Neurosciences and Cell Biology (Coimbra, Portugal)
2008/12/03 Nuclear and mitochondrial effects of sanguinarine on mouse melanoma k1735-M2 cells Annual Reunion of Portuguese Society of Pharmacology
Portuguese Society of Pharmacology (Lisboa, Portugal)
2008/12/03 Pharmacological and toxicological activity of phenolic acids on breast cancer cell models. Annual Reunion of Portuguese Society of Pharmacology
Portuguese Society of Pharmacology (Lisboa, Portugal)
2007/12/05 Different concentrations of berberine result in distinct cellular localization patterns and cell cycle effects in a melanoma cell line Annual Reunion of Portuguese Society of Pharmacology
Portuguese Society of Pharmacology (Coimbra, Portugal)
2007/12/05 Antiproliferative activity of ferulic and caffeic acid derivatives on tumor cell lines – Structure-function relationships and direct effects on mitochondria. Annual Reunion of Portuguese Society of Pharmacology
Portuguese Society of Pharmacology (Coimbra, Portugal)
2007/12/05 Mitochondrially-targetted effects of berberine on K1735-M2 mouse melanoma cells – comparison with direct effects on isolated mitochondrial fractions. Annual Reunion of Portuguese Society of Pharmacology
Universidade de Coimbra (Coimbra, Portugal)
2007/12/05 Sanguinarine cytotoxicity on mouse melanoma K1735-M2 cells: Role of nuclear and mitochondrial interactions. Annual Reunion of Portuguese Society of Pharmacology
Universidade de Coimbra (Coimbra, Portugal)
2006/09/21 Phenolic Derivatives as Potential Anticancer Agents International Conference on Oxidative Stress in Skin Medicine and Biology
University of Athens (Andros, Greece)
2006/03/24 A New Challenge for Anticancer Therapy International Courses on Toxicology
University of Coimbra (Coimbra, Portugal)
2004/05/04 Glutamatergic signalling is involved in the processing of APP. Simposium de Pós-Graduação
Universidade Aveiro (Aveiro, Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2021/02 - Current Profiling the metabolic reprogramming of Sarcoma
Co-supervisor
Universidade de Lisboa Faculdade de Medicina, Portugal
2020/11/02 - Current The role of LDL- cholesterol in metabolic remodeling and aggressiveness of breast cancer cells.
Supervisor
 Faculdade de Medicina de Lisboa - 24th Program- Education to Science Application (Other)
Instituto de Medicina Molecular, Portugal
2021/02/01 - 2021/03/12 The role of LDL-cholesterol in metabolic remodeling of breast cancer cells
Co-supervisor
Instituto de Medicina Molecular, Portugal
2019/05/01 - 2020/12/16 Metabolic Alterations in Lung Metastasis
Co-supervisor of Sofia Dalla Volta
Instituto de Medicina Molecular, Portugal
2020/02 - 2020/09 How altered mitochondria are relevant for tumor progression
Co-supervisor
Instituto de Medicina Molecular, Portugal
2012/10 - 2013/06 Lupane triterpenoids as terapeutic target against breast cancer cells
Co-supervisor
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2012/11 - 2013/05 Mitochondrial characterization of breast cancer cell lines.
Co-supervisor
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2012/09 - 2013 Role of SIRT3 on Doxorubicin induced Toxicity on H9c2 Cardiomyoblasts
Co-supervisor
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2018/09/21 - 2018/09/22 SINAL 2018 – 9TH Meeting on Signal Transduction (2018/09/21 - 2018/09/22)
Meeting (Other)
 Instituto de Medicina Molecular, Portugal
2018/04/04 - 2018/04/06 Joint Lab Retreat (2018/04/04 - 2018/04/06)
Round table
 Instituto de Medicina Molecular, Portugal
2017/06/01 - 2017/06/02 SINAL 2017 – 8TH Meeting on Signal Transduction (2017/06/01 - 2017/06/02)
Meeting (Other)
 Instituto de Medicina Molecular, Portugal
2016/03/14 - 2016/03/16 João Barata Lab Retreat (2016/03/14 - 2016/03/16)
Round table (Co-organisor)
 Instituto de Medicina Molecular, Portugal
2014/12/17 - 2014/12/20 XVIII Congress of the Portuguese Biochemical Society (2014/12/17 - 2014/12/20)
Congress (Member of the Organising Committee)
 Sociedade Portuguesa de Bioquímica, Portugal
2013/04/17 - 2013/04/20 47th Annual Meeting of the European Society for Clinical Investigation (2013/04/17 - 2013/04/20)
Congress (Member of the Organising Committee)
 CNC.IBILI, Portugal
2013/04/17 - 2013/04/20 Mitochondrial Physiology: From Basic Research to the Clinic (2013/04/17 - 2013/04/20)
Workshop (Member of the Organising Committee)
 CNC.IBILI, Portugal
2010/05/11 - 2010/05/14 Survival or Death as a Matter of Fat : International Courses on Toxicology (2010/05/11 - 2010/05/14)
Meeting (Member of the Organising Committee)
 CNC.IBILI, Portugal
2009/05/05 - 2009/05/09 Mitochondria: Between Life and Death: International Courses on Toxicology (2009/05/05 - 2009/05/09)
Meeting (Member of the Organising Committee)
 CNC.IBILI, Portugal
2008/04/09 - 2008/04/11 Metabolic Toxicology, From Pathway to Organism: International Courses on Toxicology (2008/04/09 - 2008/04/11)
Meeting (Member of the Organising Committee)
 CNC.IBILI, Portugal
2007/03/21 - 2007/03/23 Stem cells as a Tool in Toxicology : International Courses on Toxicology (2007/03/21 - 2007/03/23)
Meeting (Member of the Organising Committee)
 CNC.IBILI, Portugal
2006/03/22 - 2006/03/24 Smart Toxicology: Subcellular Targets of Anti-cancer Therapy : International Courses on Toxicology (2006/03/22 - 2006/03/24)
Meeting (Member of the Organising Committee)
 CNC.IBILI, Portugal

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2020/12/18 “Sensitivity profile of triple-negative breast cancer cell lines to combination therapies including RANKL blockade”
(Thesis) Main arguer
 João Brito Colaço Carvalho Belo (Master)
Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal
2020/09/04 How altered mitochondria are relevant for tumour progression
Supervisor
 Louise Moonen (Other)
UC Leuven-Limburg, Belgium
2014/09/08 Role of SIRT3 on Doxorubicin-induced Toxicity on H9c2 Cardiomyoblasts
Supervisor
 Ana Raquel Ligeiro Coelho (Master)
Universidade de Coimbra, Portugal

Association member

Society Organization name Role
2014/01/01 - Current Sociedade Portuguesa de Bioquímica
2013/01/01 - Current Associação Portuguesa de Investigação em Cancro
2013/01/01 - Current European Association for Cancer Research
2010/01/01 - Current Sociedade Portuguesa para o estudo das aves Voluntária
2003/11/01 - 2006/05/01 Hera - associação para a valorização e promoção do património Co-fundadora; Vice-presidente e gestora de projectos
1998/11/02 - 2003/12/31 Conselho de estudantes de biologia de Évora

Conference scientific committee

Conference name Conference host
2019/04 - Current XIII Annual CAML PhD Students’ Meeting 2019 Lisboa
2014/12/19 - Current XVIII Congress of the Portuguese Biochemical Society Coimbra

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2020/02 - Current Oncometabolismo Ciências Biofarmacêuticas (Mestrado integrado) Universidade de Lisboa Faculdade de Farmácia, Portugal
2019/02 - Current Oncometabolismo Ciências Biofarmacêuticas (Mestrado integrado) Universidade de Lisboa Faculdade de Farmácia, Portugal
2014/02/10 - 2014/03/04 Molecular Biology of Cancer Biologia Celular e Molecular (Mestrado integrado) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2013/02/11 - 2013/03/04 Molecular Biology of Cancer Biologia Celular e Molecular (Mestrado integrado) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2012/02/01 - 2012/03/01 Molecular Biology of Cancer Biologia Celular e Molecular (Mestrado integrado) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal

Interview (newspaper / magazine)

Activity description Newspaper / Forum
2015/03/17 Investigadores do laboratório MitoXT do Centro de Neurociências e Biologia Celular da Universidade de Coimbra examinam como estas mudanças podem servir como alvo terapêutico Agencia Ibero-Americana para la difusion de la ciencia y la technologia
2014/10/31 Betulinic acid derivative compounds disturb mitochondria of breast cancer cells and induce cell death Associação Portuguesa de Investigação em Cancro

Journal scientific committee

Journal title (ISSN) Publisher
2021/02 - Current Frontiers in Oncology Frontiers in Bioscience
2021/02 - Current Frontiers in Cell and Developmental Biology Frontiers in BioScience
2019/01 - Current European Journal of Clinical Investigation Wiley (Blackwell Publishing)
2016/01 - Current European Journal of Cell Biology Elsevier
2014/10/15 - Current Current Topics in Medicinal Chemistry (1568-0266) Bentham Science
2013/02/20 - Current Toxicology in Vitro (0887-2333) Elsevier
2012/07/26 - Current Oxidative Medicine and Cellular Longevity (1942-0994) Hindawi Limited
2012/01 - Current Nature Scientific Reports Springer Nature
Distinctions

Other distinction

2009 Student Scholarship
Jackson Laboratory, United States
2007 Short-term Scholarship
Fundação Calouste Gulbenkian, Portugal
2007 Research Scholarship
University of Minnesota Medical School - Duluth Campus, United States
2006 Grant for Scientific Internship at U.S.A. laboratories
Fundação Luso-Americana, Portugal