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Curriculum Vitae
Maria Joao Romão
Maria João Romão got her PhD in Chemistry in 1989 at Instituto Superior Técnico, Lisbon and was a AvHumboldt post-doctoral
fellow working with the Nobel Laureate Prof. Robert Huber at the Max Planck Institute for Biochemistry, Martinsried, Germany.
She got her Habilitation in Biochemistry at Faculdade de Ciências e Tecnologia, NOVA University of Lisbon, in 2001 and, since
2012, she is Full Professor of Biochemistry and Structural Biology at the same University. She is the founding Director of
the Research Unit on Applied Biomolecular Sciences, UCIBIO (from 2014 to 2023). Her research group on Macromolecular Crystallography
(http://sites.fct.unl.pt/xtal) has several areas of interest focused on molybdoenzymes (aldehyde oxidases, arsenite oxidases
and formate dehydrogenases) and their enzymatic mechanisms, glycan-binding and cellulosomal proteins and methods for protein
crystallization. She has supervised/co-supervised 17 PhD students and is the Principal investigator in 7 project(s) and Researcher
in 25 project(s). Since 2022 she is the local coordinator of the Horizon Europe ERA-Chair project CryoEM@NOVA for the implementation
of the first CryoEM lab at NOVA. In the period 2012-2022 she was the Portuguese Delegate to the European Synchrotron Radiation
Laboratory (ESRF) and the Portuguese observer at the Scientific Advisory Committee of ALBA Synchrotron. Since 2017 is Co-Editor
of Acta Crystallographica F. She is co-author of over 160 SCI publications, 10 book chapters and her work has received over
6600 citations, h-index= 45
Identification
Personal identification
- Full name
- Maria Joao Romão
Citation names
- Romão, Maria
- Maria Joao Romao
Author identifiers
- Ciência ID
- 3315-C689-4557
- ORCID iD
- 0000-0002-3004-0543
- Google Scholar ID
- CRCXDwYAAAAJ
- Researcher Id
- A-4115-2013
- Scopus Author Id
- 7004694870
Email addresses
- mjr@fct.unl.pt (Professional)
Websites
- https://sites.fct.unl.pt/xtal (Scholar)
- https://novaresearch.unl.pt/en/persons/maria-jo%C3%A3o-rom%C3%A3o (Professional)
- https://www.ucibio.pt/research-groups/lab/xtal-macromolecular-crystallography (Professional)
Knowledge fields
- Natural sciences - Biological Sciences - Biochemistry
Languages
Language | Speaking | Reading | Writing | Listening | Peer-review |
---|---|---|---|---|---|
English | Advanced (C1) | Advanced (C1) | Advanced (C1) | Advanced (C1) | |
German | Advanced (C1) | Intermediate (B1) | Intermediate (B1) | Advanced (C1) | |
French | Intermediate (B1) | Advanced (C1) | Intermediate (B1) | Intermediate (B1) |
Education
Degree | Classification | |
---|---|---|
2001/05/10
Concluded
|
Biochemistry (Título de Agregado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
"n.a." (THESIS/DISSERTATION)
|
n.a. |
1989
Concluded
|
Chemistry (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
""Reacções de cetonas com carbenóides de lítio: estudos estruturais e mecanísticos"." (THESIS/DISSERTATION)
|
Distinção e Louvor |
1978
Concluded
|
Engenharia Quimica (Licenciatura)
Universidade de Lisboa Instituto Superior Técnico, Portugal
"n.a." (THESIS/DISSERTATION)
|
16 |
Affiliation
Teaching in Higher Education
Category Host institution |
Employer | |
---|---|---|
2012/06/01 - Current | Full Professor (University Teacher) | Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal |
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal | ||
1998/09/01 - 2012/05/30 | Associate Professor (University Teacher) | Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal |
1989/01/26 - 1998/09/02 | Assistant Professor (University Teacher) | Universidade de Lisboa Instituto Superior Técnico, Portugal |
1979/01/02 - 1989/01/25 | Assistant (University Teacher) | Universidade de Lisboa Instituto Superior Técnico, Portugal |
Positions / Appointments
Category Host institution |
Employer | |
---|---|---|
2014 - 2020 | Conselho científico/técnico-científico ou orgão correspondente | Universidade Nova de Lisboa, Portugal |
2013/02/25 - 2017/11/14 | President of the Chemistry Department | Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal |
Others
Category Host institution |
Employer | |
---|---|---|
1998/09/02 - Current | Group Leader - Structural Biology (Xtal@FCT-NOVA) | Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal |
2014/12/31 - 2023/02/01 | Founding Director of the Research Unit UCIBIO | Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal |
Universidade Nova de Lisboa, Portugal | ||
1992/02/01 - 1998/09/01 | Group Leader - Macromolecular Crystallography | Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal |
Projects
Grant
Designation | Funders | |
---|---|---|
2021/01/01 - Current | Understanding enzymatic CO2 reduction for enhanced hybrid catalysts
PTDC/BII-BBF/2050/2020
Co-Principal Investigator (Co-PI)
Fundação para a Ciência e a Tecnologia, Portugal
|
Fundação para a Ciência e a Tecnologia
Ongoing
|
2022/11/11 - 2027/12/31 | CryoEM@NOVA: a cryo electron microscopy hub enabling drug discovery
Supervisor
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
UCIBIO- Unidade de Ciências Biomoleculares Aplicadas, Portugal |
Horizon 2020
Ongoing
|
2023/01/01 - 2024/06/30 | Novos biossensores para avaliação rápida do metabolismo oral do azoto: um estudo transversal
2022.04940.PTDC
Egas Moniz - Cooperativa de Ensino Superior Crl, Portugal
Unidade de Ciências Biomoleculares Aplicadas, Portugal |
Fundação para a Ciência e a Tecnologia
Ongoing
|
2022/01 - 2023/06 | Structural and biochemical characterization of PHA synthases towards novel Polyhydroxyalkanoates
EXPL/BIA-BQM/1300/2021
EXPL/BIA-BQM/1300/2021
Associação para a Inovação e Desenvolvimento da FCT, Portugal
Unidade de Ciências Biomoleculares Aplicadas, Portugal |
Fundação para a Ciência e a Tecnologia
Ongoing
|
2018/10/01 - 2021/09/30 | Detoxification of Hydrogen Peroxide by Pathogenic Bacteria - E.coli Tri-haem peroxidase as a model (Co-PI)
PTDC/BIA-BQM/29442/2017
Researcher
Associação para a Inovação e Desenvolvimento da FCT, Portugal
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal |
Fundação para a Ciência e a Tecnologia
Ongoing
|
2018/10/01 - 2021/09/30 | Fighting Staphylococcus aureus - Peptidoglycan amidation as a new target
PTDC/BIA-MIC/31645/2017
Researcher
Associação para a Inovação e Desenvolvimento da FCT, Portugal
Universidade Nova de Lisboa, Portugal |
Fundação para a Ciência e a Tecnologia
Ongoing
|
2018/09/17 - 2021/09/16 | Bacterial ABC-type Multitask Energizers: one ATPase fits all? (Co-PI)
PTDC/BIA-MIC/30696/2017
Researcher
Associação para a Inovação e Desenvolvimento da FCT, Portugal
|
Fundação para a Ciência e a Tecnologia
Ongoing
|
2018/09/01 - 2021/08/31 | Glycan-human microbiome interaction: glycan diversity and recognition in the human gut with impact on health and nutrition
PTDC/BIA-MIB/31730/2017
Researcher
Associação para a Inovação e Desenvolvimento da FCT, Portugal
Universidade de Aveiro, Portugal |
Fundação para a Ciência e a Tecnologia
Ongoing
|
2016/04/01 - 2019/04/01 | Targeting p53 family proteins: on the route to new anticancer agents
PTDC/DTP-FTO/1981/2014
Researcher
Universidade do Minho, Portugal
Universidade de Coimbra, Portugal Associação para a Inovação e Desenvolvimento da FCT, Portugal |
Fundação para a Ciência e a Tecnologia Fundação para a Ciência e a Tecnologia Concluded
|
2016/01 - 2019/01 | Aldehyde Oxidases in Drug Metabolism and Biocatalysis: Searching for the Substrate Specificity and Catalytic Mechanism<br>
PTDC/BBB-BEP/1185/2014
Principal investigator
Associação para a Inovação e Desenvolvimento da FCT, Portugal
UCIBIO- Unidade de Ciências Biomoleculares Aplicadas, Portugal |
Fundação para a Ciência e a Tecnologia Fundação para a Ciência e a Tecnologia Concluded
|
2016/01 - 2018/12 | CtIncipedia – A multidisciplinary approach to study Chlamydia trachomatis inclusion membrane (Inc) proteins
PTDC/IMI-MIC/1300/2014
Researcher
Associação para a Inovação e Desenvolvimento da FCT, Portugal
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal |
Fundação para a Ciência e a Tecnologia Fundação para a Ciência e a Tecnologia Ongoing
|
2016/01 - 2018/12 | An integrative structural biology approach to characterise the protein-carbohydrate microbial recognition (PI from Romao group)
PTDC/BBB-BEP/0869/2014
Researcher
Associação para a Inovação e Desenvolvimento da FCT, Portugal
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal |
Fundação para a Ciência e a Tecnologia Fundação para a Ciência e a Tecnologia Concluded
|
2015/12 - 2018/11 | Reduction of CO2 for sustainable biofuel production
Researcher
|
Fundação para a Ciência e a Tecnologia
Concluded
|
2013/07/01 - 2017/03/31 | Modern Structural Biology: Resources for the advancement of in-house X-ray Crystallography (PI from Romao group)
RECI/BBB-BEP/0124/2012
Researcher
Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
Associação para a Inovação e Desenvolvimento da FCT, Portugal Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal |
Fundação para a Ciência e a Tecnologia Fundação para a Ciência e a Tecnologia Concluded
|
2013/07/01 - 2015/12/31 | Amidation of the peptidoglycan of Gram-positive bacteria: an unexplored potential target for antibiotics
PTDC/BIA-MIC/3195/2012
Researcher
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
Associação para a Inovação e Desenvolvimento da FCT, Portugal |
Fundação para a Ciência e a Tecnologia
Concluded
|
2013/01/01 - 2015/12/31 | ENZYMATIC CATALYSIS - seeking a global picture
EXCL/QEQ-COM/0394/2012
Researcher
Universidade do Porto Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares, Portugal
Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal Associação para a Inovação e Desenvolvimento da FCT, Portugal |
Fundação para a Ciência e a Tecnologia Fundação para a Ciência e a Tecnologia, I.P. Concluded
|
2013/04 - 2015/04 | Ionic liquid-based systems for protein crystallization
PTDC/BBB-BEP/3058/2012
Researcher
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
Associação para a Inovação e Desenvolvimento da FCT, Portugal |
Fundação para a Ciência e a Tecnologia, I.P. Fundação para a Ciência e a Tecnologia Concluded
|
2012/02 - 2015/01 | Mammalian and Bacterial Aldehyde Oxidases: Structure, mechanism and insights into cofactor binding and protein maturation
(PI from Romao group)
PTDC/BIA-PRO/118377/2010
Researcher
Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
Associação para a Inovação e Desenvolvimento da FCT, Portugal Universidade do Porto Faculdade de Ciências, Portugal |
Fundação para a Ciência e a Tecnologia, I.P. Fundação para a Ciência e a Tecnologia Concluded
|
2010/02 - 2014/01 | Engineered biomimetics for large-scale enrichment of phosphoproteins
PTDC/EBB-BIO/102163/2008
Researcher
Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal |
Fundação para a Ciência e a Tecnologia, I.P. Fundação para a Ciência e a Tecnologia Concluded
|
2010/01/01 - 2013/06/30 | Structure and function of novel Glycoside Hydrolases and Carbohydrate-Binding Modules of Clostridium thermocellum cellulosome
PTDC/BIA-PRO/103980/2008
Researcher
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal |
Fundação para a Ciência e a Tecnologia Fundação para a Ciência e a Tecnologia, I.P. Concluded
|
2010/01 - 2013/06 | The Cellulosome assembly: structure, function and specificity of new cellulases and supramolecular complexes (PI from Romao
group)
PTDC/QUI-BIQ/100359/2008
Researcher
Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
Associação para a Inovação e Desenvolvimento da FCT, Portugal Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal |
Fundação para a Ciência e a Tecnologia, I.P. Fundação para a Ciência e a Tecnologia Concluded
|
2009/01 - 2012/09 | Production of a stable form of human phenylalanine hydroxylase: towards the 3D structure determination.
PTDC/QUI/64023/2006
Researcher
Universidade de Lisboa Faculdade de Farmácia, Portugal
|
Fundação para a Ciência e a Tecnologia, I.P. Fundação para a Ciência e a Tecnologia Concluded
|
2009/01/01 - 2011/12/31 | Structure and function of novel carbohydrate-binding modules and cohesin-dockerin protein complexes from Clostridium thermocellum
PTDC/BIA-PRO/69732/2006
Researcher
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal |
Fundação para a Ciência e a Tecnologia Fundação para a Ciência e a Tecnologia, I.P. Concluded
|
2008/04/01 - 2011/12/31 | Structural characterization of mRNA localization mechanisms (PI from Romao group)
PTDC/BIA-PRO/80486/2006
Researcher
Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
|
Fundação para a Ciência e a Tecnologia Fundação para a Ciência e a Tecnologia, I.P. Concluded
|
2008/01 - 2011/09 | A combined approach of X-ray Crystallography, NMR and Computational Chemistry for the study of the molecular interactions
that define the ligand specificity in cellulosomal Carbohydrate Binding Modules (PI from Romao group)
PTDC/QUI/68286/2006
Researcher
Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal Universidade do Porto Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares, Portugal |
Fundação para a Ciência e a Tecnologia, I.P. Fundação para a Ciência e a Tecnologia Concluded
|
2008/01/01 - 2011/07/31 | Structural and functional studies of the SOUL/HBP family of heme binding proteins
PTDC/QUI/64203/2006
Researcher
Universidade de Aveiro, Portugal
Universidade de Aveiro CICECO, Portugal Associação para a Inovação e Desenvolvimento da FCT, Portugal |
Fundação para a Ciência e a Tecnologia Fundação para a Ciência e a Tecnologia, I.P. Concluded
|
2008/01/02 - 2011/06/30 | Xanthine Oxidase-Related Enzymes: Structure, Function and Specificity
PTDC/QUI/64733/2006
Principal investigator
Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
|
Fundação para a Ciência e a Tecnologia Fundação para a Ciência e a Tecnologia, I.P. Concluded
|
2007/01 - 2009/06 | New molybdo and copper cofactors in proteins isolated from sulfate reducers
Researcher
|
Fundação para a Ciência e a Tecnologia, I.P. |
2007/01 - 2009/04 | Molecular determinants of ligand specificity in carbohydrate-binding modules and cohesin-dockerin complexes (PI from Romao
group)
Researcher
|
Fundação para a Ciência e a Tecnologia, I.P. |
2007/01 - 2008/11 | Structural and Functional Characterization of Nitrate Reductases and Formate Dehydrogenases
Principal investigator
|
Fundação para a Ciência e a Tecnologia, I.P. |
2000/04/01 - 2004/03/31 | HPRN-CT-1999-00084, The mechanism, specificity and inhibition of enzymes belonging to the xanthine oxidase family : medical
and industrial applications (8 EU partners; PT coordinator)
Principal investigator
Universidade Nova de Lisboa, Portugal
|
European Commission
Concluded
|
2000 - 2004 | A crystallographic contribution to the understanding of the structure and function of Mo-enzymes
POCTI/1999/BME/35078
POCTI/1999/BME/35078
Principal investigator
Universidade Nova de Lisboa, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
1999 - 2001 | Molecular Biology and Structural Studies in Metalloproteins
PRAXIS/C/BIA/11089/1998
Principal investigator
Universidade Nova de Lisboa, Portugal
|
Fundação para a Ciência e a Tecnologia, I.P.
Concluded
|
1996/11 - 1999/10 | BIO4-CT96-0413 “Construction of Novel Redox Proteins from modular building blocks” (5 EU Partners; PT coordinador)
Principal investigator
Universidade Nova de Lisboa Departamento de Química, Portugal
|
European Commission
Concluded
|
1993 - 1996 | ID: CHRX930243 Pteridines: biosynthesis, regulation and pharmacology (7 EU participants; PT coordinator)
Principal investigator
Universidade Nova de Lisboa, Portugal
|
European Commission
Concluded
|
Contract
Designation | Funders | |
---|---|---|
2023/03/01 - 2026/02/28 | Descoberta de proteínas do microbioma humano selectivas para O-glicanos ¿ ferramentas para novas abordagens na investigação
em cancro
2022.06104.PTDC
Associação para a Inovação e Desenvolvimento da FCT, Portugal
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal |
Fundação para a Ciência e a Tecnologia
Ongoing
|
2021/01/01 - 2025/12/31 | Institute for Health and Bioeconomy
LA/P/0140/2020
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal
Universidade de Lisboa Instituto de Bioengenharia e Biociências, Portugal Universidade NOVA de Lisboa, Portugal INESC Microsistemas e Nanotecnologias, Portugal Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal Associação para a Inovação e Desenvolvimento da FCT, Portugal Unidade de Ciências Biomoleculares Aplicadas, Portugal |
Fundação para a Ciência e a Tecnologia
Ongoing
|
2020/01/01 - 2023/12/31 | Applied Molecular Biosciences Unit
UIDB/04378/2020
Universidade NOVA de Lisboa, Portugal
Unidade de Ciências Biomoleculares Aplicadas, Portugal Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal Associação para a Inovação e Desenvolvimento da FCT, Portugal Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal Universidade do Porto, Portugal |
Fundação para a Ciência e a Tecnologia
Concluded
|
2020/01/01 - 2023/12/31 | Applied Molecular Biosciences Unit
UIDP/04378/2020
Universidade NOVA de Lisboa, Portugal
Unidade de Ciências Biomoleculares Aplicadas, Portugal Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal Associação para a Inovação e Desenvolvimento da FCT, Portugal Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal Universidade do Porto, Portugal |
Fundação para a Ciência e a Tecnologia
Concluded
|
Outputs
Publications
Book |
|
Book chapter |
|
Journal article |
|
Preprint |
|
Other
Other output |
|
Activities
Oral presentation
Presentation title | Event name Host (Event location) |
|
---|---|---|
2024/01 | Biological reduction of CO2 to formate by a W-dependent Formate dehydrogenase | 6th Symposium on Advanced Biological Inorganic Chemistry 7-11 January, Kalkota
(KOLKATA, India)
|
2021/09 | Integrative Structural Biology beyond 2021 | Internal Seminar Series
UCIBIO - NOVA University Lisbon
|
2019 | Mo/W-dependent Formate Dehydrogenases and the reversible interconversion of CO2 and formate (PLENARY) | 2019- International Conference on Hydrogenases
(Lisboa, Portugal)
|
2019 | What crystallography can still reveal about two families of Mo and W enzymes | 11th MOLYBDENUM & TUNGSTEN ENZYME CONFERENCE- MOTEC
(Potsdam, Germany)
|
2018 | Structural insights on Aldehyde Oxidase and Xanthine Oxidoreductase and their roles in xenobiotic metabolism | 19th SFRRI Biennial Meeting, Lisbon, 4-7 June 2018
(Lisboa, Portugal)
|
2017 | Structure and function of mammalian Aldehyde Oxidases and their role in the metabolism of drugs and xenobiotics | 14th ISABC
(Toulouse, France)
|
2017 | Mammalian Aldehyde Oxidases and their impact in xenobiotics metabolism and drug development, Santa Fe, New Mexico, USA, June 18-23 2017 | 10th MOTEC- Mo and W Enzyme Conference
( Santa Fe, New Mexico, United States)
|
2017 | The Crystal Structure of human Aldehyde Oxidase | 21st North American ISSX Meeting, Providence, Rhode Island
(Providence, Rhode Island, United States)
|
2016 | Molybdenum enzymes in Drug Metabolism and Biotransformations , | 2016- ICCC2016
(Brest, France)
|
2015 | “Aldehyde Oxidases in Drug Metabolism and Biotransformations”. (PLENARY) | 9th MOTEC - Molybdenum and Tungsten Molybdenum Conference,
(Balatonfüred, Hungary)
|
2014 | “Molybdenum Enzymes in Health and Disease” | 2014 - FrenchBIC Meeting
(Anglet, France)
|
2013 | “Unraveling new functions and modes of action of molybdenum-dependent enzymes” (PLENARY) | 2013 - 9th European Biophysics Congress EBSA2013,
(Lisboa, Portugal)
|
2011 | The Crystal Structure of Mouse Aldehyde Oxidase Homologue 1 and Insights into Substrate Specificity | MOTEC - MOLYBDENUM AND TUNGSTEN ENZYME MEETING , Alberta, Canada, August 2011,
(Alberta, Canada)
|
2007 | “Molecular and cellular biology of Mo and W" (5th GRC Mo&W enzymes) | 5th GORDON Research Conference on “Molybdenum & Tungsten Enzymes”, New-London, NH, USA, July, 2007
(New-London, NH, United States)
|
2006 | "The Role of Molybdenum in Biology" | 9th International Symposia on Metal Ions in Biology and Medicine
(Lisboa, Portugal)
|
2005 | Penta-heme Nitrite Reductase and di-heme Cytochrome c Peroxidase | International Conference in Bioinorganic Chemistry ICBIC
(Ann Arbor, United States)
|
2005 | Structural Studies on Formate Dehydrogenases (4th GRC on Mo&W enzymes) | 4th GORDON Research Conference on “Molybdenum and tungsten Enzymes”,
(Oxford, United Kingdom)
|
2004 | “Structural Studies in active and inactive forms of di-heme cytochrome c peroxidases from Pseudomonas nautica and Pseudomonas stutzeri” | 36th International Congress in Coordination Chemistry
(Merida, Mexico)
|
2003 | A Crystallographic Perspective of Molybdenum in Biology (PLENARY) | FIGIPS 2003
(Lisboa, Portugal)
|
2002 | How crystallography contributed to the understanding of Mo and W enzymes | Alumni Meeting in honor to Robert Huber
(Ringberg, Germany)
|
2002 | W-FORMATE DEHYDROGENASE And NITRATE REDUCTASE From SULFATE REDUCERS: Structures and Functions from Enzymes of the Same Family | EUROBIC-6, Lund Copenhagen
(Copenhagen, Denmark)
|
2002 | Molybdopterin-Dependent Enzymes And The Role Of The Catalytic Mo (or W) Active Site (PLENARY) | SFB Congress- Metal Mediated Reactions Modelled after Nature
(Jena, Germany)
|
2001 | “Formate Dehydrogenase From Desulfovibrio gigas : A Tungsten Enzyme Containing Se And 4x[4F-4S] Centers” (2nd GRC on Mo&W enzymes) | 2nd GORDON Research Conference on Mo and W proteins
GRC (Oxford, United Kingdom)
|
2001 | Crystallographic Studies And Mechanistic Implications On Mo And W Enzymes | 20th European Crystallographic Meeting
(Krakow, Poland)
|
1999 | Structural Studies on Molybdopterin containing Enzymes | Invited guest to the Institut für Biochemie, Universidade de Medicina de Lübeck
Institut für Biochemie, Universidade de Medicina de Lübeck, Germany (Lübeck, Germany)
|
1999 | “The first crystal structure of a dissimilatory Nitrate Reductase and implications on the reactions mechanism” (1st GRC on Mo&W enzymes) | 1st GORDON Research Conference on Molybdenum and Tungsten Enzymes
GRC (Plymouth, New Hampshire, United States)
|
1998 | Structure and Functional Aspects of Molybdopterin containing enzymes | TMR Summer School I and II
Instituto de Tecnologia Quimica e Biologica (Oeiras, Portugal)
|
1998 | Crystallography of Mo-Hydroxylases | European Xanthine Oxidase Workshop
(Roterdam, Netherlands)
|
Supervision
Thesis Title Role |
Degree Subject (Type) Institution / Organization |
|
---|---|---|
2023/09/01 - Current | Structural, dynamics and mechanistic studies of two enzymatic systems with environmental and biotechnological Impact
Co-supervisor of Guilherme Vilela Alves
|
Doctoral Program in Biochemistry (PhD)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
UCIBIO- Unidade de Ciências Biomoleculares Aplicadas, Portugal |
2023/02/01 - Current | A novel generation of DNA polymerases for qPCR molecular diagnostics
Co-supervisor of Hélvio Miguel Rodrigues Simões
|
PhD (PhD)
Universidade Nova de Lisboa Departamento de Química, Portugal
|
2019/12/02 - Current | Biointeration studies of membrane-bound catechol-O-methyltransferase polymorphic variants with commercial Parkinson’s inhibitors
Co-supervisor of Ana Margarida Grilo Gonçalves
|
Biochemistry (PhD)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
UCIBIO- Unidade de Ciências Biomoleculares Aplicadas, Portugal |
2019 - Current | Biosynthesis and a characterizations of an antibody fragment against STEAPI as a vehicle for cancer therapy
Co-supervisor of Ana Margarida Grilo Gonçalves
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Biomedicina (PhD)
Universidade da Beira Interior, Portugal
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2016 - 2022 | Peptidoglycan amidation in Gram-positive bacteria and structural studies in the Staphylococcus aureus enzymes
Co-supervisor of Francisco Leisico
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Biomolecular Sciences (PhD)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
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2013 - 2017 | Structural studies on molybdenum-dependent enzymes: from transporters to enzymes
Co-supervisor of Ana Rita Castro Otrelo Cardoso
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Bioquímica (PhD)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
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2012 - 2016 | Structural and Functional studies on the Reactivity of CORMs with plasma proteins
Co-supervisor of Marino Filipe Alves dos Santos
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Bioquímica (PhD)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
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2008 - 2014 | Crystallographic studies of proteins involved in the mRNA Localization Mechanisms in Drosophila melanogaster and Amidation
of the Peptidoglycan Residues in Staphylococcus aureus
Co-supervisor of Diana Maria Patacas Viegas Vieira
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Bioquímica (PhD)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
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2009 - 2012 | Integrated study by NMR and X-ray Crystallography on the analysis of the molecular interactions in heme-binding proteins
Co-supervisor of Filipe Miguel dos Santos Freire
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Bioquímica (PhD)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
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2008 - 2011 | Crystallographic Studies on Molybdopterin — dependent Enzymes
Supervisor of Catarina Maria Campos Coelho
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Bioquímica (PhD)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
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2002 - 2006 | Metabolismo do Metilglioxal em Tripanossomatídeos
Co-supervisor of Lídia Isabel Sebastião Barata
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Bioquímica
Universidade de Lisboa, Portugal
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2002 - 2006 | Structural Characterization of Heme and Non-heme Iron Containing Proteins
Supervisor of Teresa Sacadura Santos Silva
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Bioquímica (PhD)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
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2000 - 2004 | Biosynthesis and Function of Biological Pteridines. Structural Studies on Two Molybdopterin Containing Aldehyde Oxido-reductases,
from Desulfovibrio Desulfuricans Atcc 27774 and from Desulfovibrio Gigas, and the Gtp Cyclohydrolase I on E. Coli, Responsibl
Co-supervisor of Jorge Manuel Baeta Simões Rebelo
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Biochemistry (PhD)
Universidade Nova de Lisboa, Portugal
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1999 - 2002 | Structure & Function of Nitrate Reductase and Di-haem Cytochrome C Peroxidase
Supervisor of João Miguel Carrapa Nunes Dias
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Bioquímica (PhD)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
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1998 - 2002 | Caracterização Estrutural de Proteínas Envolvidas em Processos de Reprodução Animal
Supervisor of Ana Luísa Moreira de Carvalho
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Bioquímica (PhD)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
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1998 - 2002 | Modelação Molecular e Caracterização Estrutural de Quimeras de Proteínas de Transferência Electrónica
Co-supervisor of Carlos Manuel Alves da Costa Cunha
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Bioquímica (PhD)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
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1993 - 1997 | Crystal Structure Analysis of Metalloproteins: Cytochrome C´ and Desulforedoxin (native and Metal Reconstituted)
Supervisor of Margarida Archer Baltazar Pereira Silva Franco Frazão
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Bioquímica (PhD)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
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Event organisation
Event name Type of event (Role) |
Institution / Organization | |
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2011 - Current | 9TH CARBOHYDRATE BIOENGINEERING MEETING CBM9, May 2011, Lisbon (2011)
Conference (Member of the Organising Committee)
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2006 - Current | EUROBIC 2006 8th EUROPEAN BIOLOGICAL CHEMISTRY CONFERENCE, Aveiro (Organizing Committee) (>500 participants). (2006)
Congress (Member of the Organising Committee)
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2006 - Current | 6th IBERO-AMERICAN CONGRESS OF BIOPHYSICS (2006)
Congress (Member of the Scientific Committee)
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1998 - Current | SUMMER SCHOOL I “STRUCTURE AND FUNCTION OF METALLOPROTEINS”, ITQB, Oeiras (Organizing Committee) (ca. 80 participants). (1997)
Workshop (Member of the Organising Committee)
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1997 - Current | ECM 17 -EUROPEAN CRYSTALLOGRAPHIC MEETING (>900 participants). IST, Lisboa (Organizing Committee) (1997)
Congress (Member of the Organising Committee)
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Jury of academic degree
Topic Role |
Candidate name (Type of degree) Institution / Organization |
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---|---|---|
2018 | “Purification and Characterization of Mouse Aldehyde Oxidases”
Thesis Member
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Gokhan Kucukgoze (PhD)
Universität Potsdam Institut für Biochemie und Biologie, Germany
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2013 | “Die Funktion und Spezifität der Molybdän-Cofaktor-bindenden Chaperone für
die Formiat-Dehydrogenasen aus Escherichia coli und Rhodobacter capsulatus”
Thesis Member
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By Nadine Schwanhold (born Böhmer) (PhD)
Universität Potsdam Institut für Biochemie und Biologie, Germany
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2012 | Biosynthesis isolation and kinetic characterization of recombinant human catechol-O-methyltransferase from pichia pastoris
strains
(Thesis) Main arguer
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Augusto Quaresma Henriques Pedro (PhD)
Universidade da Beira Interior, Portugal
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2009 | New Insights Into the Structure and Function of Human Phenylalanine Hidroxylase: Interallelic Complementation Protein Misfolding
and Mechanism of Catalytic Activation
(Thesis) Main arguer
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João Paulo Travassos Leandro (PhD)
Universidade de Lisboa, Portugal
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2005 | Structural and Functional Insights Into the Role of Carbohydrate Esterases and Carbohydrate-binding Modules in Plant Cell
Wall Hydrolysis
(Thesis) Main arguer
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Márcia Alexandra da Silva Correia (PhD) |
2003 | X-ray Structure Determination of Iron-containing Proteins from Desulfovibrio Desulfuricans Atcc 27774 in Different Redox States:
Bacterioferritin and Hybrid Cluster Protein
(Thesis) Main arguer
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Sofia Isabel Vaz Queiroz de Macedo (PhD)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
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2002 | Proteínas Contendo Molibdénio e Tungsténio
(Thesis) Main arguer
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Rui Manuel de Oliveira Duarte (PhD)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
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2000 | Nmr Solution Structure of Cytochromes C3: Insight Into the Structural Origins of Functional Cooperativities (main Arguer)
(Thesis) Main arguer
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Ana Cristina Messias Coelho (PhD)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
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1996 | Cristalização e Análise Estrutural por Difracção de Raios X de Metaloproteínas Bacterianas
(Thesis) Main arguer
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José António Morais Antunes (PhD) |
Conference scientific committee
Conference name | Conference host | |
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2022/07 - 2022/07 | 25th IUBMB, 46th FEBS, 15th PABMB Congress, Lisbon (symposium co-chair) | IUBMB-FEBS-PABMB Congress |
2018 - 2018 | ECM 31, European Crystallographic Meeting , Oviedo Spain (Session Chair) | |
2010 - 2010 | IV SPANISH-PORTUGUESE BIOPHYSICAL CONGRESS (Session Chair) | |
2009 - 2009 | 6th GORDON RESEARCH CONFERENCE on “Molybdenum & Tungsten Enzymes”, (Chair) | GRC Conferences |
2007/07/01 - 2007/07/06 | 7th GORDON RESEARCH CONFERENCE on Molybdenum & Tungsten Enzymes (Vice-Chair) | Colby-Sawyer College 541 Main Street New London, NH, United States |
Evaluation committee
Activity description Role |
Institution / Organization | Funding entity | |
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2019 - Current | EXPERT Evaluation Panel of FWO (Fonds Wetenschappelijk Onderzoek ¿ Vlaanderen).
Evaluator
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Fonds Wetenschappelijk Onderzoek Vlaanderen, Belgium | Fonds Wetenschappelijk Onderzoek Vlaanderen |
2018 - Current | EVALUATION OF SEVERO OCHOA Severo Ochoa Centres of Excellence and María de Maeztu Units of Excellence
Evaluator
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Severo Ochoa Centres of Excellence and María de Maeztu Units of Excellence | |
2016 - Current | Member of the European Science Foundation (ESF) College of Expert Reviewers
Evaluator
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European Science Foundation | |
2009 - Current | Evaluator of research units and research projects by invitation of the German Science Foundation (DFG)
Evaluator
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Deutsche Forschungsgemeinschaft | |
2019/09/02 - 2024/01/20 | COORDINATOR of the evaluation process of Scientific Reports from FCT Projects (Experimental Biology and Biochemistry)
Coordinator
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Fundação para a Ciência e a Tecnologia, Portugal | Fundação para a Ciência e a Tecnologia |
Distinctions
Award
1995 | Prize - "Oeiras, A Ciência e o Desenvolvimento"
Camara Municipal de Oeiras, Portugal
Fundacao Marques de Pombal, Portugal |
1993 | "Crystal Award" - Crystallization prize for the first molybdopterin enzyme
Max-Planck-Institut für Biochemie Proteomics und Signaltransduktion, Germany
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1978 | Hylleraas Prize
Uppsala Universitet Institutionen för biokemi och organisk kemi, Sweden
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Other distinction
2019 | Member of the Scientific Advisory Committee of the Spanish Synchrotron ALBA (Portuguese Observer )
Fundação para a Ciência e a Tecnologia, Portugal
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2019 | Member of the Evaluation Panel (BIO1RP) from the Research Foundation from Flanders (FWO) |
2019 | President of the Scientific Committee of the European Union Science Olympiad (EUSO)
European Union Science Olympiad (EUSO), Ireland
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2017 | Co-Editor, Acta Crystallographica Section F
International Union of Crystallography, United Kingdom
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2016 | “100 Mulheres na Ciência” (100 Women in Science )
Pavilion of Knowledge, Portugal
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2012 | Portuguese Observer to the Council of the European Synchrotron Radiation Facility (ERSF), Grenoble
Fundação para a Ciência e a Tecnologia, Portugal
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2010 | Executive Committee of the European Synchrotron User Organization (ESUO) |
2006 | Member of the Editorial Advisory Board of the Journal of Biological Inorganic Chemistry
Society of Biological Inorganic Chemistry, Italy
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