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Pedro Brandão completed the Integrated Master in Pharmaceutical Sciences in 2011 (Faculty of Pharmacy - University of Porto). In 2022 he concluded his Phd studies in Chemistry (Catalysis and Sustainability) at the University of Coimbra - CQC/FCTUC. His PhD studies were developed in the Universidade de Coimbra, CQC, Department of Chemistry and University of Évora/LAQV-REQUIMTE. Shortly after he joined i3S - Institute for Research and Innovation in Health, at the Group of Molecular Biomaterials as Junior Researcher (i3S-University of Porto). Currently, Pedro Brandão is Assistant Professor at Egas Moniz School of Health and Science, where he continues to develop is research, focused on synthetic organic chemistry, medicinal chemistry and the application of biomaterials in drug delivery. Pedro Brandão published over 20 articles in journals, organized 7 events (national and international meetings/symposiums), and participated in several others. He has received the FISOCAT prize for best PhD Thesis in the field of Catalysis, attributed by the Portuguese Chemical Society, the PYCA (Portuguese Young Chemist Award) 2023, attributed by the Young Chemists Group of the Portuguese Chemical Society, two best poster awards, as well as some other distinctions in competitite settings (namely fellowships by the European Federation of Medicinal Chemistry and Chemical Biology to attend several events). He already had the chance to interact with over 120 collaborators from multiple countries.
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Identification

Personal identification

Full name
Pedro Manuel da Costa Gomes Brandão

Citation names

  • Brandão, Pedro

Author identifiers

Ciência ID
3319-A1CD-E42C
ORCID iD
0000-0002-1455-7470

Email addresses

  • pbrandao@qui.uc.pt (Professional)

Knowledge fields

  • Exact Sciences - Chemical Sciences - Organic Chemistry
  • Medical and Health Sciences - Basic Medicine - Medicinal Chemistry

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
French Intermediate (B1) Upper intermediate (B2) Elementary (A2) Upper intermediate (B2) Elementary (A2)
Italian Elementary (A2) Intermediate (B1) Elementary (A2) Intermediate (B1)
Hungarian Elementary (A2) Elementary (A2) Elementary (A2) Elementary (A2)
Education
Degree Classification
2021/05/19 - 2023/07/21
Concluded
 Digital Intelligence for Sustainability (Training Course) (Pós-Graduação)
Universidade de Coimbra, Portugal
2017/02/01 - 2022/02/17
Concluded
 PhD in Chemistry (Doutoramento)
Major in Catalysis and Sustainability
Universidade de Coimbra Centro de Química de Coimbra, Portugal
"Isatin and Multicomponent Reactions: Sustainable Catalytic Synthesis of Novel Bioactive Oxindole Derivatives" (THESIS/DISSERTATION)
2020/10/13 - 2021/02/09
Concluded
 Science communication - Life and health sciences (Continuing Training Course - 42 h) (Outros)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
 20/20
2006/09/01 - 2011/10/06
Concluded
 Pharmaceutical Sciences (Mestrado integrado)
Universidade do Porto Faculdade de Farmácia, Portugal
 15/20
2011/03/01 - 2011/05/31
Concluded
 Erasmus Programme (Outros)
Major in Erasmus Programme
Università degli Studi di Urbino Carlo Bo, Italy
 5/5
Affiliation

Science

Category
Host institution 		Employer
2022/06/01 - 2022/08/26 Postdoc (Research) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2014/11/01 - 2015/07/31 Researcher (Research) Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2013/12/01 - 2014/09/30 Researcher (Research) Universidade do Porto Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares, Portugal
Universidade do Porto Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares, Portugal

Teaching in Higher Education

Category
Host institution 		Employer
2022/09/01 - Current Assistant Professor (University Teacher) Egas Moniz Cooperativa de Ensino Superior CRL, Portugal
Instituto Superior de Ciências da Saúde Egas Moniz, Portugal

Other Careers

Category
Host institution 		Employer
2016/11/01 - 2017/01/31 Técnico Superior (Técnico Superior) Tata Consultancy Services Hungary, Hungary
Roche, Hungary
2016/04/27 - 2017/01/31 Consultor de Informática (Categorias e Funções Especificas) Tata Consultancy Services Hungary, Hungary
Dentsu Aegis Network Ltd, United Kingdom
2011/10/01 - 2013/11/30 Técnico Farmacêutico Especialista (Técnico Farmacêutico) Farmácia Mag, Portugal
Farmácia Mag, Portugal

Others

Category
Host institution 		Employer
2017/02 - 2022/02/17 PhD student Universidade de Coimbra, CQC, Department of Chemistry, Portugal
2017/02 - 2022/02/17 PhD student Universidade de Évora and LAQV-REQUIMTE, Portugal
Outputs

Publications

Book chapter
  1. Brandão, Pedro; Pineiro, Marta. "Mechanochemistry for Sustainable Drug Design and Active Pharmaceutical Ingredient Synthesis". In Sustainable Approaches in Pharmaceutical Sciences. Wiley Blackwell, 2023.
    Published
  2. Brandão, Pedro; Pineiro, Marta; Teresa M. V. D. Pinho e Melo. "Chapter 11: Flow Chemistry: Sequential Flow Processes for the Synthesis of Heterocycles". In Heterocycles: Synthesis, Catalysis, Sustainability, and Characterization, edited by Pineiro, Marta; Teresa M. V. D. Pinho e Melo. Wiley-VCH GmbH, 2022.
    Published
Conference abstract
  1. Moreira*, Joana; Saraíva, Lucília; Brandão, Pedro; Almeida, Joana; Nazareth, Nair; E. Sampaio-Dias, Ivo; Vasconcelos, Vitor; et al. "Norhierridin B, a new hierridin B-based hydroquinone with improved antiproliferative activity". Paper presented in 6th International Electronic Conference on Medicinal Chemistry, 2020.
    10.3390/ecmc2020-07491
  2. Brandão, Pedro; Loureiro, Joana; Carvalho, Sylvie; Hamadou, Meriem; Cravo, Sara; Moreira, Joana; Pereira, Daniela; Pinto, Madalena; Cidade, Honorina. "New prenylchalcones targeting the MDM2-p53 protein-protein interaction: synthesis and evaluation of antitumor activity". Paper presented in 4th International Electronic Conference on Medicinal Chemistry, 2018.
    Published
Conference paper
  1. Brandão, Pedro; Carvalho, Sylvie; Pereira, D.; Soares, J.; Cravo, Sara; Saraiva, Lucília; Pinto, Madalena; Cidade, Honorina. "Chalcones as promising small-molecule inhibitors of p53-MDM2 interaction". Paper presented in EFMC-ISMC 2014, 2014.
    Published
Conference poster
  1. Tiago Dionísio; Sofia Duarte; Vanessa Machado; João Botelho; José João Mendes; Pedro Fonte; Brandão, Pedro. "Fighting endodontic infections: preliminary results on a nanodentristry approach". Paper presented in 2nd Egas Moniz One Health Symposium, 2023.
  2. Mariana Costa; Brandão, Pedro; Pineiro, Marta. Corresponding author: Brandão, Pedro. "Mechanochemistry for the transformation of furanes through multicomponent reaction catalyzed by Zn". Paper presented in ISySyCat2023 - International Symposium on Synthesis and Catalysis, 2023.
  3. Monika Stanciauskaite; Brandão, Pedro; Kristina Ramanauskiene; Fonte, Pedro. Corresponding author: Brandão, Pedro. "PLGA Nanoparticles Encapsulated with Balsam Poplar Buds Aqueous Extract for Potential Ocular Delivery". Paper presented in 6th International Congress of CiiEM, 2023.
  4. Costa, Mariana; Gomes, Carla; Ana L. Cardoso; Teresa M. V. D. Pinho e Melo; Brandão, Pedro; Pineiro, Marta. "Influência do catalisador em reações multicomponente de síntese e derivatização de furano". Paper presented in VIII Encontro Científico NEQ/AAC, 2022.
  5. Brandão, Pedro; López, Óscar; Burke, Anthony J.; Pineiro, Marta. "Druglike oxindole-lactam hybrids as selective butyrylcholinesterase inhibitors". Paper presented in EFMC-YMCS Young MedicinalChemists' Symposium, 2021.
  6. Brandão, Pedro; Marques, Carolina S.; Pineiro, Marta; Burke, Anthony J.. "Isatin as a central "puzzle piece" for multicomponent reactions (MCRs)". Paper presented in ISySyCat2021 - International Symposium on Synthesis and Catalysis, 2021.
  7. Brandão, Pedro; Marques, Carolina S.; Pinto, Eugénia; Burke, Anthony J.; Pineiro, Marta. "New tryptanthrin-based Petasis adducts - design, synthesis and biological activity evaluation". Paper presented in XXVI EFMCInternational Symposium on Medicinal Chemistry (EFMC-ISMC 2021), 2021.
  8. Brandão, Pedro; Óscar López; Anthony J. Burke; Marta Pineiro. "One-step multicomponent reaction synthesis of oxindole-lactam hybrids - new agents targeting cholinesterase inhibition". Paper presented in 7PYCheM - 7th Portuguese Young Chemists Meeting, 2021.
  9. Brandão, Pedro; Laranjo, Mafalda; Botelho, Filomena; Burke, Anthony J.; Pineiro, Marta. "Engaging isatins in multicomponent reactions - Ugi adducts with promising biological activity". Paper presented in 13th National Organic Chemistry Meeting & 6th National Medicinal Chemistry Meeting, 2020.
  10. Brandão, Pedro; Burke, Anthony J.; Pineiro, Marta. "Synthesis of oxindole-peptide hybrids - application of the Ugi reaction in the preparation of new compounds with drug-like properties". Paper presented in ISySyCat2019 - International Symposium on Synthesis and Catalysis, 2019.
  11. Brandão, Pedro. "Ugi adducts of isatin - new compounds with potential biological activity". Paper presented in European School of Medicinal Chemistry (XXXIX ESMEC), 2019.
  12. Pinheiro, Daniela; Brandão, Pedro; Pineiro, Marta; Seixas-de-Melo, Sérgio. "A comprehensive investigation of tryptanthrin, an alkaloid from indigo and isatin". Paper presented in 6th Portuguese Young Chemists Meeting, 2018.
  13. Brandão, Pedro; Pinheiro, Daniela; Seixas-de-Melo, Sérgio; Pineiro, Marta. "Microwave-assisted synthesis of Tryptanthrin from Indigo: an alternative route for an important scaffold in Medicinal Chemistry". Paper presented in 12th National Organic Chemistry Meeting/5th National Medicinal Chemistry Meeting, 2018.
  14. Cidade, Honorina; Machado, C.; Pinto, P.; Almeida, J. D.; Brandão, Pedro; Loureiro, J.; Salvador, J.; et al. "New Chalcone Derivatives: Synthesis and Antitumor Activity Evaluation". Paper presented in 12th National Organic Chemistry Meeting/5th National Medicinal Chemistry Meeting, 2018.
  15. Brandão, Pedro; Burke, Anthony J.. "Oxindole Hybrids: the Quest for New Molecules with Drug-Like Properties (preliminary studies)". Paper presented in International Symposium on Synthesis and Catalysis (ISySyCat2017), 2017.
  16. Brandão, Pedro; Pinheiro, Daniela; Seixas-de-Melo, Sérgio; Pineiro, Marta. "One-pot and one-step microwave- assisted synthesis of Tryptanthrin – a relevant natural product in Medicinal Chemistry". Paper presented in International Symposium on Synthesis and Catalysis (ISySyCat2017), 2017.
  17. Ramos, H.; Gomes, S.; Leão, M.; Soares, J.; Raimundo, L.; Queiroz, G.; Brandão, Pedro; et al. "LEM2: a new small molecule inhibitor of the p73-MDM2 interaction". Paper presented in 8th Meeting of Young Researchers at UP IJUP’15, 2015.
  18. Lemos, Agostinho; Brandão, Pedro; Palmeira, Andreia; Pinto, Madalena; Saraiva, Lucília; Sousa, Emília. "Design and synthesis of new xanthone derivatives as potential disruptors of p53:MDM2 interaction". Paper presented in XX Encontro Luso-Galego de Química, 2014.
  19. Brandão, Pedro; Carvalho, S.; Pereira, D.; Soares, J.; Cravo, Sara; Saraiva, Lucília; Pinto, Madalena; Cidade, Honorina. "Chalcones as promising small-molecule  inhibitors  of  p53-MDM2  interaction". Paper presented in International Symposium  on  Medicinal  Chemistry, 2014.
  20. Fernandes, Carla; Brandão, Pedro; Santos, Alexandre; Tiritan, Maria Elizabeth; Pinto, Madalena. "Enantioseparation of seven xanthone derivatives on ten chiral HPLC columns – comparative studies". Paper presented in 7º Encontro Nacional de Cromatografia, 2012.
  21. Fernandes, Carla; Brandão, Pedro; Tiritan, Maria Elizabeth; Cass, Quezia B.; Pinto, Madalena. "Application of Polysaccharide-based Stationary Phases for Enantiomeric  Resolution  of  Chiral  Xanthone  Derivatives". Paper presented in 23rd International  Symposium  on  Pharmaceutical  and  Biomedical Analysis (PBA 2011), 2011.
  22. Fernandes, Carla; Brandão, Pedro; Tiritan, Maria Elizabeth; Afonso, Carlos; Cass, Quezia B.; Pinto, Madalena. "Efficient Methodology for Synthesis  of  Chiral Xanthone Derivatives in Enantiomerically Pure Form". Paper presented in 2nd National Meeting on Medicinal Chemistry, 2010.
  23. Fernandes, Carla; Brandão, Pedro; Tiritan, Maria Elizabeth; Afonso, Carlos; Cass, Quezia B.; Pinto, Madalena. "Application of polysaccharide-based stationary phases in  the  separation  of  chiral  xanthone  derivatives". Paper presented in 2nd  Portuguese  Young  Chemists  Meeting  2PYCheM, 2010.
  24. Brandão, Pedro; Fernandes, Carla; Tiritan, Maria Elizabeth; Afonso, Carlos; Cass, Quezia B.; Pinto, Madalena. "HPLC enantiosepara- tion of chiral xanthone derivatives on polysaccharide-based stationary phases". Paper presented in 3rd Meeting of Young Researchers at UP IJUP’10, 2010.
  25. Fernandes, Carla; Brandão, Pedro; Tiritan, Maria Elizabeth; Afonso, Carlos; Cass, Quezia B.; Pinto, Madalena. "Direct HPLC enantioseparation of chiral xanthones on polysaccharide and macrocyclic antibiotic-based chiral stationary phases". Paper presented in 6º Encontro Nacional de Cromatografia, 2009.
Journal article
  1. Marques, Carolina S.; Brandão, Pedro; Burke, Anthony J.. "Targeting Vascular Endothelial Growth Factor Receptor 2 (VEGFR-2): Latest Insights on Synthetic Strategies". Molecules 29 22 (2024): 5341. http://dx.doi.org/10.3390/molecules29225341.
    Published • 10.3390/molecules29225341
  2. Rehman, Mubashar; Tahir, Nayab; Sohail, Muhammad Farhan; Qadri, Muhammad Usman; Duarte, Sofia O. D.; Brandão, Pedro; Esteves, Teresa; Javed, Ibrahim; Fonte, Pedro. "Lipid-Based Nanoformulations for Drug Delivery: An Ongoing Perspective". Pharmaceutics 16 11 (2024): 1376. http://dx.doi.org/10.3390/pharmaceutics16111376.
    Published • 10.3390/pharmaceutics16111376
  3. Barroso, Livia Alves; Viegas, Cláudia; Stanciauskaite, Monika; Macedo, Ana S.; Lemos, Iara Lopes; da Costa, Joyce Maria Gomes; Schmiele, Marcio; et al. "Impact of the Use of Cryoprotectants in the Production of Freeze-Dried Soluble Coffee from Cold Brew Arabica Coffee". Food and Bioprocess Technology (2024): http://dx.doi.org/10.1007/s11947-024-03387-z.
    Published • 10.1007/s11947-024-03387-z
  4. Puerta, Adrián; González-Bakker, Aday; Brandão, Pedro; Pineiro, Marta; Burke, Anthony J.; Giovannetti, Elisa; Fernandes, Miguel X.; Padrón, José M.. "Early pharmacological profiling of isatin derivatives as potent and selective cytotoxic agents". Biochemical Pharmacology 222 (2024): 116059. http://dx.doi.org/10.1016/j.bcp.2024.116059.
    Published • 10.1016/j.bcp.2024.116059
  5. Kumar, Mahesh; Virmani, Tarun; Kumar, Girish; Deshmukh, Rohitas; Sharma, Ashwani; Duarte, Sofia; Brandão, Pedro; Fonte, Pedro. "Nanocarriers in Tuberculosis Treatment: Challenges and Delivery Strategies". Pharmaceuticals 16 10 (2023): 1360. http://dx.doi.org/10.3390/ph16101360.
    Open access • 10.3390/ph16101360
  6. Marques, Carolina S.; Brandão, Pedro. "The Asymmetric Petasis Borono-Mannich Reaction: Insights on the Last 15 Years". Catalysts 13 6 (2023): 1022. http://dx.doi.org/10.3390/catal13061022.
    10.3390/catal13061022
  7. Brandão, Pedro; Pineiro, Marta; Anthony J. Burke. Corresponding author: Pineiro, Marta. "Tryptanthrin and Its Derivatives in Drug Discovery: Synthetic Insights". Synthesis (2022): https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0040-1719901.
    In press
  8. Brandão, Pedro; Puerta, Adrián; Padrón, José M; Kuznetsov, Maxim L; Burke, Anthony J; Pineiro, Marta. "Ugi adducts of isatin as promising antiproliferative agents with druglike properties". Asian Journal of Organic Chemistry (2021): http://dx.doi.org/10.1002/ajoc.202100684.
    In press • 10.1002/ajoc.202100684
  9. Karissa Resnik; Pedro Brandão; Emanuele Amorim Alves. "DARK Classics in Chemical Neuroscience: Bucinnazine". ACS Chemical Neuroscience 12 19 (2021): 3527-3534. https://doi.org/10.1021/acschemneuro.1c00522.
    10.1021/acschemneuro.1c00522
  10. Brandão, Pedro; López, Óscar; Leitzbach, Luisa; Stark, Holger; Fernández-Bolaños, José G.; Burke, Anthony J.; Pineiro, Marta. "Ugi Reaction Synthesis of Oxindole-Lactam Hybrids as Selective Butyrylcholinesterase Inhibitors". ACS Medicinal Chemistry Letters 12 11 (2021): 1718-1725. http://dx.doi.org/10.1021/acsmedchemlett.1c00344.
    Published • 10.1021/acsmedchemlett.1c00344
  11. Brandão, Pedro; Marques, Carolina; Pinto, Eugénia; Pineiro, Marta; BURKE, Anthony. "Petasis adducts of tryptanthrin - synthesis, biological activity evaluation and druglikeness assessment". New Journal of Chemistry 45 (2021): 14633-14649. https://doi.org/10.1039/D1NJ02079J.
    Published
  12. Brandão, Pedro; Marques, Carolina S.; Carreiro, Elisabete P.; Pineiro, M.; Burke, Anthony J.. "Engaging Isatins in Multicomponent Reactions (MCRs) - Easy Access to Structural Diversity". The Chemical Record 21 4 (2021): 924-1037. https://doi.org/10.1002/tcr.202000167.
    Published • 10.1002/tcr.202000167
  13. Brandão, Pedro; Marques, Carolina; Burke, Anthony J.; Pineiro, Marta. "The application of isatin-based multicomponent-reactions in the quest for new bioactive and druglike molecules". European Journal of Medicinal Chemistry 211 (2021): 113102. https://doi.org/10.1016/j.ejmech.2020.113102.
    10.1016/j.ejmech.2020.113102
  14. Pinheiro, Daniela; Brandão, Pedro; Seixas de Melo, J.Sérgio; Pineiro, Marta. "Triptantrina: da Natureza ao Laboratório". Química 45 162 (2021): 195-200. 10.52590/M3.P697.A30002440.
    Published
  15. Brandão, Pedro; Anthony J. Burke; Marta Pineiro. "Reações Multicomponente - Uma Ferramenta Valiosa na Descoberta e Produção de Fármacos". Química 44 159 (2020): 264-276. 10.52590/M3.P694.A30002331.
    Published
  16. Brandão, Pedro; Burke, Anthony J.; Pineiro, Marta. "A decade of Indium-catalyzed multicomponent reactions (MCRs)". European Journal of Organic Chemistry 2020 34 (2020): 5501-5513. https://doi.org/10.1002/ejoc.202000596.
    Published • 10.1002/ejoc.202000596
  17. Brandão, Pedro; Moreira, Joana; Almeida, Joana; Nazareth, Nair; Sampaio-Dias, Ivo E.; Vasconcelos, Vitor; Martins, Rosário; et al. "Norhierridin B, a New Hierridin B-Based Hydroquinone with Improved Antiproliferative Activity". Molecules 25 7 (2020): 1578. https://doi.org/10.3390/molecules25071578.
    Published • 10.3390/molecules25071578
  18. Pinheiro, Daniela; Pineiro, Marta; Pina, João; Brandão, Pedro; Galvão, Adelino M.; Seixas de Melo, J.Sérgio. "Tryptanthrin from indigo: Synthesis, excited state deactivation routes and efficient singlet oxygen sensitization". Dyes and Pigments 175 (2019): 108125. https://doi.org/10.1016/j.dyepig.2019.108125.
    Published • 10.1016/j.dyepig.2019.108125
  19. Pedro Brandão; Marta Pineiro; Teresa M. V. D. Pinho e Melo. "Cover Feature: Flow Chemistry: Towards A More Sustainable Heterocyclic Synthesis (Eur. J. Org. Chem. 43/2019)". European Journal of Organic Chemistry 2019 43 (2019): 7187-7187. https://doi.org/10.1002/ejoc.201901638.
    10.1002/ejoc.201901638
  20. Brandão, Pedro; Pineiro, Marta; Pinho e Melo, Teresa M. V. D.. "Flow Chemistry: Towards A More Sustainable Heterocyclic Synthesis". European Journal of Organic Chemistry 2019 43 (2019): 7188-7217. https://doi.org/10.1002/ejoc.201901335.
    Published • 10.1002/ejoc.201901335
  21. Brandão, Pedro; BURKE, Anthony. "Catalytic Ugi Reactions: Current Advances, Future Challenges - Part 1". Chimica Oggi - Chemistry Today 37 4 (2019): 21-25.
    Published
  22. Brandão, Pedro; Burke, Anthony J.. "Catalytic Ugi Reactions: Current Advances, Future Challenges - Part 2". Chimica Oggi - Chemistry Today 37 4 (2019): 18-21.
  23. Brandão, Pedro; Pinheiro, Daniela; Sérgio Seixas de Melo, J.; Pineiro, Marta. "I2/NaH/DMF as oxidant trio for the synthesis of tryptanthrin from indigo or isatin". Dyes and Pigments 173 (2019): 107935. 10.1016/j.dyepig.2019.107935.
    Published • 10.1016/j.dyepig.2019.107935
  24. Lemos; Gomes; Loureiro; Brandão; Palmeira; Pinto; Saraiva; Sousa. "Synthesis, Biological Evaluation, and In Silico Studies of Novel Aminated Xanthones as Potential p53-Activating Agents". Molecules 24 10 (2019): 1975. http://dx.doi.org/10.3390/molecules24101975.
    Published • 10.3390/molecules24101975
  25. Brandão, Pedro; Burke, Anthony J.. "Recent advances in the asymmetric catalytic synthesis of chiral 3-hydroxy and 3-aminooxindoles and derivatives: Medicinally relevant compounds". Tetrahedron 74 38 (2018): 4927-4957. 10.1016/j.tet.2018.06.015.
    Published • 10.1016/j.tet.2018.06.015
  26. Brandão, Pedro; Loureiro, Joana B.; Carvalho, Sylvie; Hamadou, Meriem Hadjer; Cravo, Sara; Moreira, Joana; Pereira, Daniela; et al. "Targeting the MDM2-p53 protein-protein interaction with prenylchalcones: Synthesis of a small library and evaluation of potential antitumor activity". European Journal of Medicinal Chemistry 156 (2018): 711-721. http://dx.doi.org/10.1016/j.ejmech.2018.07.037.
    Published • 10.1016/j.ejmech.2018.07.037
  27. Alves, Emanuele Amorim; Brandão, Pedro; Neves, João Filipe; Cravo, Sara Manuela; Soares, José Xavier; Grund, Jean-Paul C.; Duarte, José Alberto; et al. "Repeated subcutaneous administrations of krokodil causes skin necrosis and internal organs toxicity in Wistar rats: putative human implications". Human Psychopharmacology: Clinical and Experimental 32 3 (2017): e2572. http://dx.doi.org/10.1002/hup.2572.
    Published • 10.1002/hup.2572
  28. Alves, Emanuele E.; Brandao, Pedro; Magalhaes, Teresa; Carvalho, Felix; Dinis-Oliveira, Ricardo J.. "Fatal Intoxications in the North of Portugal: 12 Years of Retrospective Analysis". Current Drug Safety 12 1 (2017): 39-45. http://dx.doi.org/10.2174/1574886311666160724212407.
    10.2174/1574886311666160724212407
  29. Sara Gomes, Ana; Brandão, Pedro; Sofia Garcia Fernandes, Carla; Ramos Pinto Correia da Silva, Marta; Emília da Silva Pereira de Sousa, Maria; Maria de Magalhães Pinto, Madalena. "Drug-like Properties and ADME of Xanthone Derivatives: The Antechamber of Clinical Trials". Current Medicinal Chemistry 23 32 (2016): 3654-3686. http://dx.doi.org/10.2174/0929867323666160425113058.
    10.2174/0929867323666160425113058
  30. Alves, E.A.; Brandão, P.; Neves, J.F.; Cravo, S.M.; Soares, J.X.; Duarte, J.A.; Grund, J.C.; et al. "Short-term toxicodynamics of krokodil in wistar rats following repeated subcutaneous administration". Toxicology Letters 258 (2016): S130. http://dx.doi.org/10.1016/j.toxlet.2016.06.1514.
    Published • 10.1016/j.toxlet.2016.06.1514
  31. Fonseca, Joana; Marques, Sandra; Silva, Patrícia; Brandão, Pedro; Cidade, Honorina; Pinto, Madalena; Bousbaa, Hassan. "Prenylated Chalcone 2 Acts as an Antimitotic Agent and Enhances the Chemosensitivity of Tumor Cells to Paclitaxel". Molecules 21 8 (2016): 982. http://dx.doi.org/10.3390/molecules21080982.
    10.3390/molecules21080982
  32. Fernandes C; Brandão P; Santos A; Tiritan ME; Afonso C; Cass QB; Pinto MM. "Resolution and determination of enantiomeric purity of new chiral derivatives of xanthones using polysaccharide-based stationary phases.". (2012):
    10.1016/j.chroma.2012.07.058
  33. Fernandes, Carla; Brandão, Pedro; Tiritan, Maria Elizabeth; Afonso, Carlos; Cass, Quezia B.; Pinto, Madalena. "Efficient methodology for synthesis of chiral xanthone derivatives in enantiomerically pure form". Revista Portuguesa de Farmácia 52 4 (Supl.) (2010): 153-153.
    Published
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2022/09/21 Catalysis and Multicomponent reactions - a perfect match in the quest for new bioactive compounds 28th Ibero-American Catalysis Congress (CICAT)
Universidade Federal do Rio Grande do Norte (UFRN) (Virtual Event, Brazil)
2022/04/21 Highway to bioactivity: isatin-based multicomponent reactions 14th National Organic Chemistry Meeting & 7th National Medicinal Chemistry Meeting
Nova School of Science and Technology - Lisbon (Caparica, Portugal)
2021/12/06 Multicomponent reactions (MCRs): a sustainable strategy in drug discovery 6th CATSUS Workshop
(Portugal)
2021/04/26 Ugi reaction and isatin: a "fast track" for the discovery of new bioactive oxindoles ECHC - XXIX European Colloquium on Heterocyclic Chemistry
INSA and University of Rouen, France (Virtual event) (Virtual Event)
2020/11/20 Synthesis of novel isatin based druglike compounds via MCRs 5th CATSUS Workshop
CATSUS (Portugal)
2018/11/19 Chemistry and Pharmacology of Oxindole Derivatives- the quest for new drug candidates AppState Seminar
Department of Chemistry and Fermentation Sciences at the Appalachian State University (Boone (North Carolina), United States)
2017/11/02 Sustainable asymmetric catalytic synthesis of novel oxindole hybrids with potential biological activity 3rd CATSUS Workshop
FCUL (Lisbon, Portugal)
2016/02/12 Toxicological Studies on "Krokodil" in Wistar Rats 1st Meeting on the Emergence of Forensic Sciences
(Porto, Portugal)
2015/03/27 A hybridization approach to obtain new xanthone derivatives as potential inhibitors of p53:MDM2 interaction 3rd National Meeting of Chemistry Students
(Aveiro, Portugal)
2012/11/23 Comparative Study of the Resolution of Chiral Derivatives of Xanthones on Different Types of HPLC Stationary Phases  1st  Luso-Brazilian  Symposium  on Science, XI Encontro de Iniciação Científica (XI ENIC), II Encontro de Iniciação Tecnológica (II ENIT)
(Vassouras, Brazil)
2011/02/17 Efficient method for evaluation of the enantiomeric purity of chiral xanthone derivatives 4th Meeting of Young Researchers at UP (IJUP’11)
(Porto, Portugal)

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2023/09/05 - 2023/09/08 International Symposium on Synthesis and Catalysis (ISySyCat2023) (2023/09/05 - 2023/09/08)
Congress (Member of the Organising Committee)
 Universidade de Évora, Portugal
2021/08/31 - 2021/09/03 International Symposium on Synthesis and Catalysis (ISySyCat2021) (2021/08/31 - 2021/09/03)
Symposium (Member of the Organising Committee)
 Universidade de Évora, Portugal
2019/09/03 - 2019/09/06 International Symposium on Synthesis and Catalysis (ISySyCat 2019) (2019/09/03 - 2019/09/06)
Symposium (Member of the Organising Committee)
 Universidade de Évora, Portugal
2019/04/06 - 2019/04/06 Semifinal das Olimpíadas de Química Júnior 2019 (2019/04/06 - 2019/04/06)
Other (Member of the Organising Committee)
 Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2018/09/09 - 2018/09/14 XXVI Congresso Ibero-Americano de Catálise (CICAT2018) (2018/09/09 - 2018/09/14)
Congress (Member of the Organising Committee)
 Universidade de Coimbra, Portugal
2018/04/14 - 2018/04/14 Semifinal das Olimpíadas de Química Júnior 2018 (2018/04/14 - 2018/04/14)
Other (Member of the Organising Committee)
 Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2018/01/17 - 2018/01/19 12th National Organic Chemistry Meeting (12ENQO) & 5th National Medicinal Chemistry Meeting (5ENQT) (2018/01/17 - 2018/01/19)
Congress (Member of the Organising Committee)
 Universidade de Coimbra, Portugal
2017/09/05 - 2017/09/08 International Symposium on Synthesis and Catalysis (ISySyCat2017) (2017/09/05 - 2017/09/08)
Congress (Member of the Organising Committee)
 Universidade de Évora, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2023/07/12 - 2023/07/12 Challenge Based Learning & Design Thinking
Other
 Challenge Based Learning & Design Thinking
Egas Moniz Cooperativa de Ensino Superior CRL, Portugal
2023/07/10 - 2023/07/10 Competências Pedagógicas Básicas
Other
 Competências Pedagógicas Básicas
Egas Moniz Cooperativa de Ensino Superior CRL, Portugal
2023/02/10 - 2023/02/10 Diversificando a avaliação da aprendizagem: dos fundamentos à prática (JIIDP)
Seminar
 Diversificando a avaliação da aprendizagem: dos fundamentos à prática (Jornadas Interinstitucionais de Desenvolvimento Pedagógico)
Universidade do Minho, Portugal
2023/02/08 - 2023/02/08 Utilização do Moodle: Ideias e Sugestões para Aumentar a Participação de Alunos nas Unidades Curriculares (JIIDP)
Seminar
 Jornadas Interinstitucionais de Desenvolvimento Pedagógico
Universidade Lusófona de Humanidades e Tecnologias Centro de Estudos e Intervenção em Educação e Formação, Portugal
2023/02/02 - 2023/02/02 Novas velhas maneiras de ensinar técnicas laboratoriais (JIIDP)
Seminar
 Novas velhas maneiras de ensinar técnicas laboratoriais (Jornadas Interinstitucionais de Desenvolvimento Pedagógico)
Universidade do Algarve, Portugal
2023/02/02 - 2023/02/02 Operacionalizando Future Skills na sala de aula (JIIDP)
Seminar
 Operacionalizando Future Skills na sala de aula (Jornadas Interinstitucionais de Desenvolvimento Pedagógico)
Instituto Politécnico de Setúbal, Portugal
2021/10/22 - 2021/10/22 Intellectual Property Management Workshop (1st edition)
Workshop
 Intellectual Property Management Workshop
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2021/09/09 - 2021/09/10 EFMC-YMCS Young MedicinalChemists' Symposium
Symposium
 EFMC-YMCS Young MedicinalChemists' Symposium
Swiss Chemical Society, Switzerland
2021/08/29 - 2021/09/02 XXVI EFMC International Symposium on Medicinal Chemistry (EFMC-ISMC 2021)
Symposium
 XXVI EFMC International Symposium on Medicinal Chemistry (EFMC-ISMC 2021)
Swiss Chemical Society, Switzerland
2021/05/05 - 2021/05/31 Building and Leading Research Teams
Workshop
 Building and Leading Research Teams
Universidade do Porto Faculdade de Psicologia e de Ciências da Educação, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2021/05/19 - 2021/05/21 7PYCheM - 7th Portuguese Young Chemists Meeting
Meeting
 7PYCheM - 7th Portuguese Young Chemists Meeting
Centro de Investigação de Montanha, Portugal
2021/04/29 - 2021/04/29 Impact, Scientific Production Evaluation and Responsible Metrics
Seminar
 Impact, Scientific Production Evaluation and Responsible Metrics (Formação iiiUC: Ferramentas de Apoio à Investigação)
Universidade de Coimbra, Portugal
2021/04/26 - 2021/04/28 XXIX European Colloquium on Heterocyclic Chemistry (ECHC)
Conference
 XXIX European Colloquium on Heterocyclic Chemistry (ECHC)
Université de Rouen, France
2021/04/15 - 2021/04/16 Open Science Workshop
Workshop
 Open Science Workshop
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2020/01/15 - 2020/01/17 13th National Organic Chemistry Meeting & 6th National Medicinal Chemistry Meeting
Meeting
 13th National Organic Chemistry Meeting & 6th National Medicinal Chemistry Meeting
Universidade de Aveiro, Portugal
2019/06/30 - 2019/07/04 European School of Medicinal Chemistry (XXXIX ESMEC)
Meeting
 European School of Medicinal Chemistry (XXXIX ESMEC)
Università degli Studi di Urbino Carlo Bo, Italy
2019/01/29 - 2019/01/29 Strategies in the discovery of drugs
Workshop
 Strategies in the discovery of drugs
Universidade de Coimbra Departamento de Química, Portugal
2018/09/27 - 2018/09/28 1st drugs R&D PhD Symposium - Translational Science: from Academia to Industry
Symposium
 1st drugs R&D PhD Symposium – Translational Science: from Academia to Industry
Universidade de Coimbra Faculdade de Farmácia, Portugal
2018/05/07 - 2018/05/11 NMR in health and disease: from protein-ligand interactions to small molecules in tissues
Workshop
 NMR in health and disease: from protein-ligand interactions to small molecules in tissues
Universidade de Coimbra Departamento de Química, Portugal
2014/05/20 - 2014/05/20 Design small molecule src kinase inhibitors as a therapeutic approach against cancer
Conference
 Design small molecule src kinase inhibitors as a therapeutic approach against cancer
Universidade do Porto Faculdade de Farmácia, Portugal
2011/07/21 - 2011/07/21 From Molecular Recognition to Organocatalysis
Conference
 From Molecular Recognition to Organocatalysis
Universidade do Porto Faculdade de Farmácia, Portugal
2011/07/21 - 2011/07/21 Stereoselective synthesis of unnatural amino acids
Conference
 Stereoselective synthesis of unnatural amino acids
Universidade do Porto Faculdade de Farmácia, Portugal
2010/07/23 - 2010/07/23 LC-MS/MS: from small molecules to macromolecule
Symposium
 Symposium
Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2010/07/19 - 2010/07/23 Mass Spectrometry in the 21 st  Century Summer School
Universidade do Porto Faculdade de Farmácia, Portugal
2009/07/07 - 2009/07/10 Medicinal Chemistry and drug design Summer School
Universidade do Porto Faculdade de Farmácia, Portugal
2009/07/06 - 2009/07/10 HPLC: from fundamentals to application Summer school
Universidade do Porto Faculdade de Farmácia, Portugal

Conference scientific committee

Conference name Conference host
2023/11/27 - 2023/11/30 IV Jornadas Científicas Universitárias e Politécnicas Egas Moniz
2023/10/26 - 2023/10/28 X Iberoamerican Congress of Pharmaceutical Sciences Faculty of Pharmacy - University of Coimbra

Interview (newspaper / magazine)

Activity description Newspaper / Forum
2019/08/01 #Iamamedicinalchemist/chemicalbiologist MedChemWatch - Summer Edition 2019

Mentoring / Tutoring

Topic Student name
2021/01/02 - 2021/07/12 Síntese e avaliação in silico de druglikeness da triptantrina e seus derivados Arianna C. Marante
2020/01/02 - 2020/07/29 Synthesis of isatin derivatives - application of the Ugi reaction in the preparation of novel compounds with potential biological activity Eduarda Santos Ventura
Distinctions

Award

2024 Best PhD Thesis in Organic Chemistry
Sociedade Portuguesa de Química, Portugal
2023 PYCA - Portuguese Young Chemist Award
Sociedade Portuguesa de Química, Portugal
2022 FISOCAT Award - Best PhD Thesis in Catalysis
Sociedade Portuguesa de Química, Portugal
2021 Best Poster "Organic and Biomolecular Chemistry"
ISySyCat2021, Portugal
2020 Best Poster in Organic Chemistry
13th National Organic Chemistry Meeting & 6th National Medicinal Chemistry Meeting, Portugal

Other distinction

2021 Selected as a Mentee for the EFMC-YSN Mentoring Programme
European Federation for Medicinal Chemistry and Chemical Biology (EFMC), Portugal
2021 EFMC Grant to attend the EFMC International Symposium on Medicinal Chemistry (EFMC-ISMC 2021) and 7th EFMC Young MedicinalChemist Symposium (EFMC-YMCS 2021)
European Federation for Medicinal Chemistry and Chemical Biology (EFMC), Portugal
2019 EFMC-ESMEC Fellowship to attend the European School of Medicinal Chemistry 2019
EFMC-ESMEC, Italy