Susana Maria dos Santos Costa (371A-9C60-E497)

Curriculum Vitae

Susana Maria dos Santos Costa

Susana Costa completed her BSc degree in Biochemistry in 2017 and her MSc degree in Cellular and Molecular Biology in 2019, at the University of Coimbra. She published 3 papers in peer-reviewed journals. Her MSc thesis was developed at the "RNA & Infection" laboratory, under the supervision of Dr Ana Eulalio, at the Center for Neurosciences and Cell Biology (CNC-CIBB, University of Coimbra). This work allowed her to specialize in the study of host-pathogen interactions, the intracellular lifestyle of Salmonella Typhimurium and microRNAs. She has worked as a Research Fellow at the "RNA & Infection" and "Functional Genomics and RNA-Based Therapeutics" headed by Dr. Ana Eulalio and Dr. Miguel Mano, respectively. She is currently a PhD student in the PhD Programme in Experimental Biology and Biomedicine (PDBEB). Her PhD work is focused on identifying and characterizing host factors that regulate the intracellular lifestyle of various bacterial pathogens, including Salmonella.

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Identification

Personal identification

Full name: Susana Maria dos Santos Costa
Date of birth: 1996/06/11
Gender: Female

Citation names

Costa, Susana

Author identifiers

Ciência ID: 371A-9C60-E497
ORCID iD: 0000-0002-3020-5918

Email addresses

susana.mscosta96@gmail.com (Professional)

Telephones

Telephone

231419040 (Professional)

Knowledge fields

Natural sciences - Biological Sciences - Cell Biology
Natural sciences - Biological Sciences - Molecular Biology
Natural sciences - Biological Sciences - Microbiology

Languages

Language	Speaking	Reading	Writing	Listening	Peer-review
English	Advanced (C1)	Advanced (C1)	Advanced (C1)	Advanced (C1)
Portuguese (Mother tongue)

Education

	Degree	Classification
2020 - 2025 Ongoing	Experimental Biology and Biomedicine (Doutoramento) Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2019 Concluded	Cellular and Molecular Biology (Mestrado) Major in Área de especialização: Biologia Molecular e Celular Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal "Towards a better understanding of host cell requirements for Salmonella cytosolic replication" (THESIS/DISSERTATION)	19/20
2017 Concluded	Biochemistry (Licenciatura) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal "Notch signalling in adipose tissue after bariatric surgery in diabetic rats: implications for angiogenesis" (THESIS/DISSERTATION)	17/20

Affiliation

Others

	Category Host institution	Employer
2020/12/01 - Current	PhD Student, RNA & Infection Laboratory	Centro de Inovação em Biomedicina e Biotecnologia, Portugal
	Centro de Inovação em Biomedicina e Biotecnologia, Portugal
2019/11/15 - 2020/11/30	Research Fellow (MSc), RNA & Infection Laboratory/Functional Genomics and RNA-based Therapeutics Laboratory	Centro de Inovação em Biomedicina e Biotecnologia, Portugal
	Centro de Inovação em Biomedicina e Biotecnologia, Portugal
2018/06/01 - 2019/09/04	MSc Thesis Project, RNA & Infection Laboratory	Centro de Inovação em Biomedicina e Biotecnologia, Portugal
	Centro de Inovação em Biomedicina e Biotecnologia, Portugal
2018/04/02 - 2018/04/30	Laboratory Rotation, RNA & Infection Laboratory	Centro de Inovação em Biomedicina e Biotecnologia, Portugal
	Centro de Inovação em Biomedicina e Biotecnologia, Portugal
2018/01/29 - 2018/02/23	Laboratory Rotation, Laboratory of Physiology	Universidade de Coimbra Faculdade de Medicina, Portugal
	Universidade de Coimbra Faculdade de Medicina, Portugal
2017/02/05 - 2017/07/15	BSc Final Project, Laboratory of Physiology	Universidade de Coimbra Faculdade de Medicina, Portugal
	Universidade de Coimbra Faculdade de Medicina, Portugal
2016/07/18 - 2016/09/16	Research Trainee, Laboratory of Microbiology	Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
	Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal

Projects

Grant

	Designation	Funders
2020/12/01 - Current	Deciphering host cell microRNAs controlling Salmonella replication and persistence within macrophages 2020.06572.BD PhD Student Fellow Centro de Inovação em Biomedicina e Biotecnologia, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2020/02/01 - 2020/11/30	Intracellular Staphylococcus aureus: deciphering bacterial and cellular factors involved in host cell invasion by clinically relevant strains to define new therapeutic approaches (StaphIN) Infect-ERA/0001/2015 Research Fellow Centro de Inovação em Biomedicina e Biotecnologia, Portugal	European Commission Seventh Framework Programme for Research and Technological Development Health

Outputs

Publications

Conference poster	Costa, Susana; Caio Franco; Miguel Mano; Ana Eulálio. Corresponding author: Costa, Susana. "Identification of host microRNAs regulating the infection of macrophages by invasive and non-invasive Salmonella strains". Paper presented in Antimicrobial Chemotherapy Conference 2025, 2025. Costa, Susana; Caio Franco; Miguel Mano; Ana Euláio. "Identification of host microRNAs regulating the infection of macrophages by invasive and non-invasive Salmonella strains". Paper presented in Non-coding RNA World 2024: Exploring Mechanisms, Designing Medicines, 2024. Costa, Susana; Caio Franco; Miguel Mano; Ana Eulálio. "Identification of host microRNAs regulating the infection of macrophages by invasive and non-invasive Salmonella strains". Paper presented in EMBO \| EMBL Symposium: The non-coding genome, 2023. Costa, Susana; Caio Franco; Miguel Mano; Ana Eulálio. "Identification of host microRNAs regulating the infection of macrophages by invasive and non-invasive Salmonella strains". Paper presented in BEB DAY 2023 - Science Challenges: This fight of ours, 2023. Franco, C. H.; Costa, Susana; Mano, Miguel; Eulalio, Ana. "Identification of host microRNAs regulating the infection of macrophages by invasive and non-invasive Salmonella strains". Paper presented in XI ptRNA Meeting - RNA in Disease, 2023.
Journal article	Lisowski, Clivia; Dias, Jane; Costa, Susana; Silva, Ricardo Jorge; Mano, Miguel; Eulalio, Ana. "Dysregulated endolysosomal trafficking in cells arrested in the G1 phase of the host cell cycle impairs Salmonella vacuolar replication". Autophagy (2021): 1-16. http://dx.doi.org/10.1080/15548627.2021.1999561. 10.1080/15548627.2021.1999561 Aguilar, Carmen; Costa, Susana; Maudet, Claire; Vivek-Ananth, R. P.; Zaldívar-López, Sara; Garrido, Juan J.; Samal, Areejit; Mano, Miguel; Eulalio, Ana. "Reprogramming of microRNA expression via E2F1 downregulation promotes Salmonella infection both in infected and bystander cells". Nature Communications 12 1 (2021): http://dx.doi.org/10.1038/s41467-021-23593-z. 10.1038/s41467-021-23593-z Eickhoff, Hans; Rodrigues, Tiago; Neves, Inês; Marques, Daniela; Ribeiro, Diana; Costa, Susana; Seiça, Raquel; Matafome, Paulo. "Effect of Sleeve Gastrectomy on Angiogenesis and Adipose Tissue Health in an Obese Animal Model of Type 2 Diabetes". Obesity Surgery 29 9 (2019): 2942-2951. 10.1007/s11695-019-03935-z
Thesis / Dissertation	Costa, Susana Maria dos Santos. "Towards a better understanding of host cell requirements for Salmonella cytosolic replication". Master, 2019. http://hdl.handle.net/10316/88111.

Activities

Event participation

	Activity description Type of event	Event name Institution / Organization
2024/12 - Current	“Superbugs: The invisible threat” - Development and execution of multiple activities including ludic games to perform with elementary school students. The activities were focused on microbiology, bacterial pathogens and the threat of antibiotic resistance to public health.	Semana da Ciência & Tecnologia CiBB Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2024/09 - 2024/09	European Research Night - Communicate Science to Society Awareness about multi-resistant bacteria and the efforts of scientists to find new strategies to combat infections Development of didactic activities for different group ages, including a card game and environmental microbiology experiments.	European Research Night Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2023/09 - 2023/09	European Research Night - Communicate Science to Society Awareness about multi-resistant bacteria and the efforts of scientists to find new strategies to combat infections Development of didactic activities for different group ages, including a card game and environmental microbiology experiments. Exhibition	European Research Night Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2022/09 - 2022/09	European Research Night - Communicate Science to Society Awareness about multi-resistant bacteria and the efforts of scientists to find new strategies to combat infections Development of didactic activities for different group ages, including a card game and environmental microbiology experiments. Exhibition	European Research Night Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2022/01/18 - 2022/01/19	PDBEB Students meeting Symposium	BEB Day 2022 - The Overview Effect Universidade de Coimbra, Portugal
2021/03/15 - 2021/03/19	Lecturers address multiple aspects of infection, host responses to strategies to fight infectious agents and highlight the importance of constantly monitoring environmental microbiology and epidemiology. Workshop	Fighting Infection Course Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2021/02/01 - 2021/02/05	The course was focused on the principles, design, and application of different types of screenings (interference RNA; drug; CRISPR...), applied to diverse models (in vitro and in vivo) and diverse research fields. Practical sessions of microscopy image analysis using Columbus and Cellprofiler software. Workshop	High-Throughput Screening for Target and Drug Discovery Course Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2019/11/11 - 2019/11/11	Meeting with theoretical sessions for the basis of Scanning Electron Microscopy, complemented with practical sessions: preparation of biological samples for scanning electron microscopy; negative staining (IGC). Workshop	IV Technical Meeting of Electron Microscopy Universidade de Coimbra Faculdade de Medicina, Portugal
2018/09/10 - 2018/09/10	Online course: Introduction to BSL-2. By labsafetyworkspace.org Other
2018/09/09 - 2018/09/09	Online course : Introduction to Laboratory Safety. By labsafetyworkspace.org Other
2016/05/28 - 2016/05/28	Pedagogic meeting of Chemistry Students. Participation in the workshops: "Nanomaterials"; "The use of proteomics to answer biological questions". Meeting	INPEQ - Intercâmbio Pedagógico de Estudantes de Química Universidade de Aveiro, Portugal

Association member

	Society Organization name	Role
2015 - 2018	MiniBioqs - Volunteer project that promotes the realization of basic biochemistry experiences for children to encourage the practice of science in the Pediatric Hospital of Coimbra and other Institutions.	Coordinator / Colaborator

Distinctions

Award

2020	PhD Scholarship Fundação para a Ciência e a Tecnologia, Portugal
2019	Merit Scholarship Universidade de Coimbra, Portugal
2014	Academic excellency Escola Secundária da Mealhada, Portugal