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Vaughn Cooper.
Identification

Personal identification

Full name
Vaughn Cooper

Citation names

  • Cooper, Vaughn

Author identifiers

Ciência ID
3814-218F-7170
ORCID iD
0000-0001-7726-0765
Education
Degree Classification
2004
Concluded
n/a (Pós-doutoramento)
University of Michigan, United States
"Medical Microbiology and Evolution" (THESIS/DISSERTATION)
n/a
2000
Concluded
Ecology, Evolutionary Biology, and Behavior (Doutoramento)
Michigan State University, United States
"Causes and consequences of ecological specialization in long-term evolving populations of E. coli" (THESIS/DISSERTATION)
A
1994
Concluded
Biology (Bacharelato)
Amherst College, United States
"magna cum laude" (THESIS/DISSERTATION)
A
Projects

Grant

Designation Funders
2018/08 - 2021/07 Collaborative Proposal: Role of tRNA base modifications in genetic code accuracy and bacterial fitness National Science Foundation Directorate for Biological Sciences
2016/03 - 2021/02 Predicting the emergence of antibiotic resistance through multi-omics approaches and Immune System-surveillan National Institute of Allergy and Infectious Diseases
2015/01 - 2019/12 Molecular mechanisms of adaptive diversity in Burkholderia biofilms National Institute of General Medical Sciences
2013/09 - 2017/08 The Molecular Basis of Host Adaptation and Origin of New Mutualisms National Science Foundation Directorate for Biological Sciences
2013/08 - 2016/07 Collaborative Research: Strengthening the scientific basis for decision-making: Advancing sustainability science and knowledge-action capacities in coupled coastal systems National Science Foundation Office of the Director
2009/08 - 2015/07 CAREER: Quantifying pleiotropy by parallel experimental evolution National Science Foundation Directorate for Biological Sciences
2009/07 - 2013/06 Collaborative Research: Understanding the basis of interactions between adaptive mutations and their environment National Science Foundation Directorate for Biological Sciences
2009/04 - 2012/02 The roles of adaptive radiation and phenotypic switching in biofilm diversity National Institute of Allergy and Infectious Diseases
2009/05 - 2011/10 Ecological population structure and emergence of virulent Vibrio parahaemolyticus National Institute of Allergy and Infectious Diseases
Outputs

Publications

Journal article
  1. Michelle R. Scribner; Amelia C. Stephens; Justin L. Huong; Anthony R. Richardson; Vaughn S. Cooper. "The nutritional environment is sufficient to select coexisting biofilm and quorum-sensing mutants of Pseudomonas aeruginosa". Journal of Bacteriology (2022): https://doi.org/10.1128/JB.00444-21.
    10.1128/JB.00444-21
  2. Katrina B Harris; Kenneth M Flynn; Vaughn S Cooper; Deepa Agashe. "Polygenic Adaptation and Clonal Interference Enable Sustained Diversity in Experimental Pseudomonas aeruginosa Populations". Molecular Biology and Evolution (2021): https://doi.org/10.1093/molbev/msab248.
    10.1093/molbev/msab248
  3. Collin Kessler; Eisha Mhatre; Vaughn Cooper; Wook Kim; Irina S. Druzhinina. "Evolutionary Divergence of the Wsp Signal Transduction Systems in Beta- and Gammaproteobacteria". Applied and Environmental Microbiology 87 22 (2021): https://doi.org/10.1128/AEM.01306-21.
    10.1128/AEM.01306-21
  4. Anita Rana; David Patton; Nathan T Turner; Marcus M Dillon; Vaughn S Cooper; Way Sung; P J Wittkopp. "Precise measurement of the fitness effects of spontaneous mutations by droplet digital PCR in Burkholderia cenocepacia". Genetics 219 2 (2021): https://doi.org/10.1093/genetics/iyab117.
    10.1093/genetics/iyab117
  5. Matthew M. Schaefers; Benjamin X. Wang; Nicole M. Boisvert; Sarah J. Martini; Sarah L. Bonney; Christopher W. Marshall; Michael T. Laub; et al. "Evolution towards Virulence in a Burkholderia Two-Component System". mBio 12 4 (2021): https://doi.org/10.1128/mBio.01823-21.
    10.1128/mBio.01823-21
  6. Alfonso Santos-Lopez; Christopher W Marshall; Allison L Haas; Caroline Turner; Javier Rasero; Vaughn S Cooper. "The roles of history, chance, and natural selection in the evolution of antibiotic resistance". eLife 10 (2021): https://doi.org/10.7554/eLife.70676.
    10.7554/eLife.70676
  7. Salini Konikkat; Ivan Matic; Michelle R. Scribner; Rory Eutsey; N. Luisa Hiller; Vaughn S. Cooper; Joel McManus. "Quantitative mapping of mRNA 3’ ends in Pseudomonas aeruginosa reveals a pervasive role for premature 3’ end formation in response to azithromycin". PLOS Genetics 17 7 (2021): e1009634-e1009634. https://doi.org/10.1371/journal.pgen.1009634.
    10.1371/journal.pgen.1009634
  8. Eric L. Bruger; Daniel J. Snyder; Vaughn S. Cooper; Christopher M. Waters. "Correction: Quorum sensing provides a molecular mechanism for evolution to tune and maintain investment in cooperation". The ISME Journal (2021): https://doi.org/10.1038/s41396-021-00972-4.
    10.1038/s41396-021-00972-4
  9. Christopher W. Marshall; Erin S. Gloag; Christina Lim; Daniel J. Wozniak; Vaughn S. Cooper. "Rampant prophage movement among transient competitors drives rapid adaptation during infection". Science Advances (2021): https://doi.org/10.1126/sciadv.abh1489.
    10.1126/sciadv.abh1489
  10. Abigail M. Rubio; Ellen G. Kline; Chelsea E. Jones; Liang Chen; Barry N. Kreiswirth; M. Hong Nguyen; Cornelius J. Clancy; et al. "In Vitro Susceptibility of Multidrug-Resistant Pseudomonas aeruginosa following Treatment-Emergent Resistance to Ceftolozane-Tazobactam". Antimicrobial Agents and Chemotherapy 65 6 (2021): https://doi.org/10.1128/AAC.00084-21.
    10.1128/AAC.00084-21
  11. Heiko T. Kiesewalter; Carlos N. Lozano-Andrade; Mario Wibowo; Mikael L. Strube; Gergely Maróti; Dan Snyder; Tue Sparholt Jørgensen; et al. "Genomic and Chemical Diversity of Bacillus subtilis Secondary Metabolites against Plant Pathogenic Fungi". mSystems (2021): https://doi.org/10.1128/mSystems.00770-20.
    10.1128/mSystems.00770-20
  12. Eric L. Bruger; Daniel J. Synder; Vaughn S. Cooper; Christopher M. Waters. "Quorum sensing provides a molecular mechanism for evolution to tune and maintain investment in cooperation". The ISME Journal (2020): https://doi.org/10.1038/s41396-020-00847-0.
    10.1038/s41396-020-00847-0
  13. Eisha Mhatre; Daniel J. Snyder; Emily Sileo; Caroline B. Turner; Sean W. Buskirk; Nicolas L. Fernandez; Matthew B. Neiditch; Christopher M. Waters; Vaughn S. Cooper. "One gene, multiple ecological strategies: A biofilm regulator is a capacitor for sustainable diversity". Proceedings of the National Academy of Sciences 117 35 (2020): 21647-21657. https://doi.org/10.1073/pnas.2008540117.
    10.1073/pnas.2008540117
  14. Michelle R. Scribner; Alfonso Santos-Lopez; Christopher W. Marshall; Christopher Deitrick; Vaughn S. Cooper; Deborah A. Hogan. "Parallel Evolution of Tobramycin Resistance across Species and Environments". mBio (2020): https://doi.org/10.1128/mBio.00932-20.
    10.1128/mBio.00932-20
  15. Vaughn S. Cooper; Erin Honsa; Hannah Rowe; Christopher Deitrick; Amy R. Iverson; Jonathan J. Whittall; Stephanie L. Neville; et al. "Experimental Evolution In Vivo To Identify Selective Pressures during Pneumococcal Colonization". mSystems (2020): https://doi.org/10.1128/mSystems.00352-20.
    10.1128/mSystems.00352-20
  16. Daniel R Evans; Marissa P Griffith; Alexander J Sundermann; Kathleen A Shutt; Melissa I Saul; Mustapha M Mustapha; Jane W Marsh; et al. "Systematic detection of horizontal gene transfer across genera among multidrug-resistant bacteria in a single hospital". eLife (2020): https://doi.org/10.7554/eLife.53886.
    10.7554/eLife.53886
  17. Heiko T. Kiesewalter; Carlos N. Lozano-Andrade; Gergely Maróti; Dan Snyder; Vaughn S. Cooper; Tue Sparholt Jørgensen; Tilmann Weber; Ákos T. Kovács; Irene L. G. Newton. "Complete Genome Sequences of 13 Bacillus subtilis Soil Isolates for Studying Secondary Metabolite Diversity". Microbiology Resource Announcements 9 2 (2020): https://doi.org/10.1128/MRA.01406-19.
    10.1128/MRA.01406-19
  18. Caroline B. Turner; Sean W. Buskirk; Katrina B. Harris; Vaughn S. Cooper. "Negative frequency-dependent selection maintains coexisting genotypes during fluctuating selection". Molecular Ecology (2020): https://doi.org/10.1111/mec.15307.
    10.1111/mec.15307
  19. Andrew B Morgenthaler; Wallis R Kinney; Christopher C Ebmeier; Corinne M Walsh; Daniel J Snyder; Vaughn S Cooper; William M Old; Shelley D Copley. "Mutations that improve efficiency of a weak-link enzyme are rare compared to adaptive mutations elsewhere in the genome". eLife 8 (2019): https://doi.org/10.7554/eLife.53535.
    10.7554/eLife.53535
  20. Ravi K. Patel; Chunhua Song; Mark C. Weir; Kexin Shen; Daniel Snyder; Vaughn S. Cooper; Thomas E. Smithgall. "Expression of myeloid Src-family kinases is associated with poor prognosis in AML and influences Flt3-ITD kinase inhibitor acquired resistance". PLOS ONE (2019): https://doi.org/10.1371/journal.pone.0225887.
    10.1371/journal.pone.0225887
  21. Vaughn S. Cooper; Taylor M. Warren; Abigail M. Matela; Michael Handwork; Shani Scarponi. "EvolvingSTEM: a microbial evolution-in-action curriculum that enhances learning of evolutionary biology and biotechnology". Evolution: Education and Outreach 12 1 (2019): https://doi.org/10.1186/s12052-019-0103-4.
    10.1186/s12052-019-0103-4
  22. Juhan Kim; Jake J. Flood; Michael R. Kristofich; Cyrus Gidfar; Andrew B. Morgenthaler; Tobias Fuhrer; Uwe Sauer; et al. "Hidden resources in the Escherichia coli genome restore PLP synthesis and robust growth after deletion of the essential gene pdxB". Proceedings of the National Academy of Sciences 116 48 (2019): 24164-24173. https://doi.org/10.1073/pnas.1915569116.
    10.1073/pnas.1915569116
  23. Meghan A. Hartwick; Erin A. Urquhart; Cheryl A. Whistler; Vaughn S. Cooper; Elena N. Naumova; Stephen H. Jones. "Forecasting Seasonal Vibrio parahaemolyticus Concentrations in New England Shellfish". International Journal of Environmental Research and Public Health (2019): https://doi.org/10.3390/ijerph16224341.
    10.3390/ijerph16224341
  24. Alina Iovleva; Roberta T. Mettus; Christi L. McElheny; Marissa P. Griffith; Mustapha M. Mustapha; A. William Pasculle; Ryan K. Shields; Vaughn S. Cooper; Yohei Doi. "High-Level Carbapenem Resistance in OXA-232-Producing Raoultella ornithinolytica Triggered by Ertapenem Therapy". Antimicrobial Agents and Chemotherapy (2019): https://doi.org/10.1128/AAC.01335-19.
    10.1128/AAC.01335-19
  25. Alfonso Santos-Lopez; Christopher W Marshall; Michelle R Scribner; Daniel J Snyder; Vaughn S Cooper. "Evolutionary pathways to antibiotic resistance are dependent upon environmental structure and bacterial lifestyle". eLife 8 (2019): https://doi.org/10.7554/eLife.47612.
    10.7554/eLife.47612
  26. Erin S. Gloag; Christopher W. Marshall; Daniel Snyder; Gina R. Lewin; Jacob S. Harris; Alfonso Santos-Lopez; Sarah B. Chaney; et al. "Pseudomonas aeruginosa Interstrain Dynamics and Selection of Hyperbiofilm Mutants during a Chronic Infection". mBio 10 4 (2019): https://doi.org/10.1128/mBio.01698-19.
    10.1128/mBio.01698-19
  27. Evan J. Waldron; Robert B. Bourret; Daniel Snyder; Nicolas L. Fernandez; Emily Sileo; Daigo Inoyama; Joel S. Freundlich; et al. "Structural basis of DSF recognition by its receptor RpfR and its regulatory interaction with the DSF synthase RpfF". PLOS Biology (2019): https://doi.org/10.1371/journal.pbio.3000123.
    10.1371/journal.pbio.3000123
  28. Marsh JW; Pacey MP; Ezeonwuka C; Ohm SL; Snyder D; Cooper VS; Harrison LH; Doi Y; Mustapha MM. "Clostridioides difficile: a potential source of NpmA in the clinical environment.". The Journal of antimicrobial chemotherapy (2019): http://europepmc.org/abstract/med/30295814.
    10.1093/jac/dky420
  29. Torres A; Kasturiarachi N; DuPont M; Cooper VS; Bomberger J; Zemke A. "NADH Dehydrogenases in Pseudomonas aeruginosa Growth and Virulence.". Frontiers in Microbiology (2019): http://europepmc.org/abstract/med/30804898.
    10.3389/fmicb.2019.00075
  30. Dunlap DG; Marshall CW; Fitch A; Rapport SF; Cooper VS; McVerry BJ; Morris A; Kitsios GD. "Improved Detection of Culprit Pathogens by Bacterial DNA Sequencing Affects Antibiotic Management Decisions in Severe Pneumonia.". The American journal of case reports (2018): http://europepmc.org/abstract/med/30473582.
    10.12659/AJCR.912055
  31. Mustapha MM; Li B; Pacey MP; Mettus RT; McElheny CL; Marshall CW; Ernst RK; Cooper VS; Doi Y. "Phylogenomics of colistin-susceptible and resistant XDR Acinetobacter baumannii.". The Journal of antimicrobial chemotherapy (2018): http://europepmc.org/abstract/med/30124845.
    10.1093/jac/dky290
  32. Inês N. Silva; Filipa D. Pessoa; Marcelo J. Ramires; Mário R. Santos; Jörg D. Becker; Vaughn S. Cooper; Leonilde M. Moreira; Yves V. Brun. "The OmpR Regulator of Burkholderia multivorans Controls Mucoid-to-Nonmucoid Transition and Other Cell Envelope Properties Associated with Persistence in the Cystic Fibrosis Lung". Journal of Bacteriology 200 17 (2018): https://doi.org/10.1128/JB.00216-18.
    10.1128/JB.00216-18
  33. Marcus M. Dillon; Way Sung; Michael Lynch; Vaughn S. Cooper; Michael T. Laub. "Periodic Variation of Mutation Rates in Bacterial Genomes Associated with Replication Timing". mBio 9 4 (2018): https://doi.org/10.1128/mBio.01371-18.
    10.1128/mBio.01371-18
  34. Le Sage V; Nanni AV; Bhagwat AR; Snyder DJ; Cooper VS; Lakdawala SS; Lee N. "Non-Uniform and Non-Random Binding of Nucleoprotein to Influenza A and B Viral RNA.". Viruses (2018): http://europepmc.org/abstract/med/30257455.
    10.3390/v10100522
  35. JohnCarlo Kristofich; Ivan Matic; Andrew B. Morgenthaler; Wallis R. Kinney; Christopher C. Ebmeier; Daniel J. Snyder; William M. Old; Vaughn S. Cooper; Shelley D. Copley. "Synonymous mutations make dramatic contributions to fitness when growth is limited by a weak-link enzyme". PLOS Genetics 14 8 (2018): e1007615-e1007615. https://doi.org/10.1371/journal.pgen.1007615.
    10.1371/journal.pgen.1007615
  36. Caroline B. Turner; Christopher W. Marshall; Vaughn S. Cooper. "Parallel genetic adaptation across environments differing in mode of growth or resource availability". Evolution Letters 2 4 (2018): 355-367. https://doi.org/10.1002/evl3.75.
    10.1002/evl3.75
  37. Vaughn S. Cooper; Ana Cristina Gales. "Experimental Evolution as a High-Throughput Screen for Genetic Adaptations". mSphere (2018): https://doi.org/10.1128/mSphere.00121-18.
    10.1128/mSphere.00121-18
  38. Melinda R. Grosser; Andreas Peschel; Elyse Paluscio; Lance R. Thurlow; Marcus M. Dillon; Vaughn S. Cooper; Thomas H. Kawula; Anthony R. Richardson. "Genetic requirements for Staphylococcus aureus nitric oxide resistance and virulence". PLOS Pathogens 14 3 (2018): e1006907-e1006907. https://doi.org/10.1371/journal.ppat.1006907.
    10.1371/journal.ppat.1006907
  39. "New Insights from Elucidating the Role of LMP1 in Nasopharyngeal Carcinoma". Cancers (2018): http://www.mdpi.com/2072-6694/10/4/86.
    10.3390/cancers10040086
  40. Qu Y; Olonisakin T; Bain W; Zupetic J; Brown R; Hulver M; Xiong Z; et al. "Thrombospondin-1 protects against pathogen-induced lung injury by limiting extracellular matrix proteolysis.". JCI insight (2018): http://europepmc.org/abstract/med/29415890.
    10.1172/jci.insight.96914
  41. Aaron E. Lucas; Ryota Ito; Mustapha M. Mustapha; Christi L. McElheny; Roberta T. Mettus; Sarah L. Bowler; Serena F. Kantz; et al. "Frequency and Mechanisms of Spontaneous Fosfomycin Nonsusceptibility Observed upon Disk Diffusion Testing of Escherichia coli". Journal of Clinical Microbiology (2018): https://doi.org/10.1128/JCM.01368-17.
    10.1128/JCM.01368-17
  42. Leung LM; Cooper VS; Rasko DA; Guo Q; Pacey MP; McElheny CL; Mettus RT; et al. "Structural modification of LPS in colistin-resistant, KPC-producing Klebsiella pneumoniae.". The Journal of antimicrobial chemotherapy (2017): http://europepmc.org/abstract/med/28961916.
    10.1093/jac/dkx234
  43. Guo Y; Tomich AD; McElheny CL; Cooper VS; Tait-Kamradt A; Wang M; Hu F; et al. "High-Level Fosfomycin Resistance in Vancomycin-Resistant Enterococcus faecium.". Emerging infectious diseases (2017): http://europepmc.org/abstract/med/29048285.
    10.3201/eid2311.171130
  44. Feng Xu; Narjol Gonzalez-Escalona; Kevin P. Drees; Robert P. Sebra; Vaughn S. Cooper; Stephen H. Jones; Cheryl A. Whistler; Andrew J. McBain. "Parallel Evolution of Two Clades of an Atlantic-Endemic Pathogenic Lineage of Vibrio parahaemolyticus by Independent Acquisition of Related Pathogenicity Islands". Applied and Environmental Microbiology (2017): https://doi.org/10.1128/AEM.01168-17.
    10.1128/AEM.01168-17
  45. Nara Lee; Valerie Le Sage; Adalena V. Nanni; Dan J. Snyder; Vaughn S. Cooper; Seema S. Lakdawala. "Genome-wide analysis of influenza viral RNA and nucleoprotein association". Nucleic Acids Research (2017): https://doi.org/10.1093%2Fnar%2Fgkx584.
    10.1093/nar/gkx584
  46. Haidar G; Philips NJ; Shields RK; Snyder D; Cheng S; Potoski BA; Doi Y; et al. "Ceftolozane-Tazobactam for the Treatment of Multidrug-Resistant Pseudomonas aeruginosa Infections: Clinical Effectiveness and Evolution of Resistance.". Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2017): http://europepmc.org/abstract/med/29017262.
    10.1093/cid/cix182
  47. Hassan AA; Maldonado RF; Dos Santos SC; Di Lorenzo F; Silipo A; Coutinho CP; Cooper VS; et al. "Structure of O-Antigen and Hybrid Biosynthetic Locus in Burkholderia cenocepacia Clonal Variants Recovered from a Cystic Fibrosis Patient.". Frontiers in Microbiology (2017): http://europepmc.org/abstract/med/28642745.
    10.3389/fmicb.2017.01027
  48. Pankey MS; Foxall RL; Ster IM; Perry LA; Schuster BM; Donner RA; Coyle M; Cooper VS; Whistler CA. "Host-selected mutations converging on a global regulator drive an adaptive leap by bacteria to symbiosis.". (2017): http://europepmc.org/abstract/med/28447935.
    10.7554/elife.24414
  49. Erin S. Honsa; Vaughn S. Cooper; Mohammed N. Mhaissen; Matthew Frank; Jessica Shaker; Amy Iverson; Jeffrey Rubnitz; et al. "RelA Mutant Enterococcus faecium with Multiantibiotic Tolerance Arising in an Immunocompromised Host". mBio 8 1 (2017): https://doi.org/10.1128/mBio.02124-16.
    10.1128/mBio.02124-16
  50. Jiménez A; Castro JG; Munoz-Price LS; de Pascale D; Shimose L; Mustapha MM; Spychala CN; et al. "Outbreak of Klebsiella pneumoniae Carbapenemase-Producing Citrobacter freundii at a Tertiary Acute Care Facility in Miami, Florida.". (2017): http://europepmc.org/abstract/med/27923418.
    10.1017/ice.2016.273
  51. Xu F; Gonzalez-Escalona N; Haendiges J; Myers RA; Ferguson J; Stiles T; Hickey E; et al. "Sequence Type 631 Vibrio parahaemolyticus, an Emerging Foodborne Pathogen in North America.". (2017): http://europepmc.org/abstract/med/27974540.
    10.1128/jcm.02162-16
  52. Dillon MM; Sung W; Sebra R; Lynch M; Cooper VS. "Genome-Wide Biases in the Rate and Molecular Spectrum of Spontaneous Mutations in Vibrio cholerae and Vibrio fischeri.". (2017): http://europepmc.org/abstract/med/27744412.
    10.1093/molbev/msw224
  53. Peeters C; Cooper VS; Hatcher PJ; Verheyde B; Carlier A; Vandamme P. "Comparative genomics of Burkholderia multivorans, a ubiquitous pathogen with a highly conserved genomic structure.". (2017): http://europepmc.org/abstract/med/28430818.
    10.1371/journal.pone.0176191
  54. Dillon MM; Cooper VS. "The Fitness Effects of Spontaneous Mutations Nearly Unseen by Selection in a Bacterium with Multiple Chromosomes.". (2016): http://europepmc.org/abstract/med/27672096.
    10.1534/genetics.116.193060
  55. Qinglan Guo; Baixing Ding; Thomas Jové; Nicole Stoesser; Vaughn S. Cooper; Minggui Wang; Yohei Doi. "Characterization of a Novel IncHI2 Plasmid Carrying Tandem Copies of bla CTX-M-2 in a fosA6 -Harboring Escherichia coli Sequence Type 410 Strain". Antimicrobial Agents and Chemotherapy 60 11 (2016): 6742-6747. https://doi.org/10.1128/AAC.01173-16.
    10.1128/AAC.01173-16
  56. Kenneth M. Flynn; Gabrielle Dowell; Thomas M. Johnson; Benjamin J. Koestler; Christopher M. Waters; Vaughn S. Cooper; G. A. O'Toole. "Evolution of Ecological Diversity in Biofilms of Pseudomonas aeruginosa by Altered Cyclic Diguanylate Signaling". Journal of Bacteriology 198 19 (2016): 2608-2618. https://doi.org/10.1128/JB.00048-16.
    10.1128/JB.00048-16
  57. Marivic Martin; Theresa Hölscher; Anna Dragoš; Vaughn S. Cooper; Ákos T. Kovács; G. A. O'Toole. "Laboratory Evolution of Microbial Interactions in Bacterial Biofilms". Journal of Bacteriology 198 19 (2016): 2564-2571. https://doi.org/10.1128/JB.01018-15.
    10.1128/JB.01018-15
  58. Guo Q; Tomich AD; McElheny CL; Cooper VS; Stoesser N; Wang M; Sluis-Cremer N; Doi Y. "Glutathione-S-transferase FosA6 of Klebsiella pneumoniae origin conferring fosfomycin resistance in ESBL-producing Escherichia coli.". (2016): http://europepmc.org/abstract/med/27261267.
    10.1093/jac/dkw177
  59. Sung W; Ackerman MS; Dillon MM; Platt TG; Fuqua C; Cooper VS; Lynch M. "Evolution of the Insertion-Deletion Mutation Rate Across the Tree of Life.". (2016): http://europepmc.org/abstract/med/27317782.
    10.1534/g3.116.030890
  60. Inês N. Silva; Pedro M. Santos; Mário R. Santos; James E. A. Zlosnik; David P. Speert; Sean W. Buskirk; Eric L. Bruger; et al. "Long-Term Evolution of Burkholderia multivorans during a Chronic Cystic Fibrosis Infection Reveals Shifting Forces of Selection". mSystems 1 3 (2016): https://doi.org/10.1128/mSystems.00029-16.
    10.1128/mSystems.00029-16
  61. Wang Y; Diaz Arenas C; Stoebel DM; Flynn K; Knapp E; Dillon MM; Wünsche A; et al. "Benefit of transferred mutations is better predicted by the fitness of recipients than by their ecological or genetic relatedness.". (2016): http://europepmc.org/abstract/med/27091964.
    10.1073/pnas.1524988113
  62. Dillon MM; Rouillard NP; Van Dam B; Gallet R; Cooper VS. "Diverse phenotypic and genetic responses to short-term selection in evolving Escherichia coli populations.". (2016): http://europepmc.org/abstract/med/26995338.
    10.1111/evo.12868
  63. Urquhart EA; Jones SH; Yu JW; Schuster BM; Marcinkiewicz AL; Whistler CA; Cooper VS. "Environmental Conditions Associated with Elevated Vibrio parahaemolyticus Concentrations in Great Bay Estuary, New Hampshire.". (2016): http://europepmc.org/abstract/med/27144925.
    10.1371/journal.pone.0155018
  64. Silva IN; Santos PM; Santos MR; Zlosnik JE; Speert DP; Buskirk SW; Bruger EL; et al. "Long-Term Evolution of Burkholderia multivorans during a Chronic Cystic Fibrosis Infection Reveals Shifting Forces of Selection.". (2016): http://europepmc.org/abstract/med/27822534.
  65. Peeters C; Meier-Kolthoff JP; Verheyde B; De Brandt E; Cooper VS; Vandamme P. "Phylogenomic Study of Burkholderia glathei-like Organisms, Proposal of 13 Novel Burkholderia Species and Emended Descriptions of Burkholderia sordidicola, Burkholderia zhejiangensis, and Burkholderia grimmiae.". (2016): http://europepmc.org/abstract/med/27375597.
    10.3389/fmicb.2016.00877
  66. Dillon MM; Sung W; Lynch M; Cooper VS. "The Rate and Molecular Spectrum of Spontaneous Mutations in the GC-Rich Multichromosome Genome of Burkholderia cenocepacia.". (2015): http://europepmc.org/abstract/med/25971664.
    10.1534/genetics.115.176834
  67. Whistler CA; Hall JA; Xu F; Ilyas S; Siwakoti P; Cooper VS; Jones SH. "Use of Whole-Genome Phylogeny and Comparisons for Development of a Multiplex PCR Assay To Identify Sequence Type 36 Vibrio parahaemolyticus.". (2015): http://europepmc.org/abstract/med/25832299.
    10.1128/JCM.00034-15
  68. Ellis CN; Traverse CC; Mayo-Smith L; Buskirk SW; Cooper VS. "Character displacement and the evolution of niche complementarity in a model biofilm community.". (2015): http://europepmc.org/abstract/med/25494960.
    10.1111/evo.12581
  69. Xu F; Ilyas S; Hall JA; Jones SH; Cooper VS; Whistler CA. "Genetic characterization of clinical and environmental Vibrio parahaemolyticus from the Northeast USA reveals emerging resident and non-indigenous pathogen lineages.". (2015): http://europepmc.org/abstract/med/25904905.
    10.3389/fmicb.2015.00272
  70. O'Rourke D; FitzGerald CE; Traverse CC; Cooper VS. "There and back again: consequences of biofilm specialization under selection for dispersal.". (2015): http://europepmc.org/abstract/med/25717335.
    10.3389/fgene.2015.00018
  71. Abebe-Akele F; Tisa LS; Cooper VS; Hatcher PJ; Abebe E; Thomas WK. "Genome sequence and comparative analysis of a putative entomopathogenic Serratia isolated from Caenorhabditis briggsae.". (2015): http://europepmc.org/abstract/med/26187596.
    10.1186/s12864-015-1697-8
  72. Cooper VS. "The origins of specialization: insights from bacteria held 25 years in captivity.". (2014): http://europepmc.org/abstract/med/24558348.
    10.1371/journal.pbio.1001790
  73. Cooper, V.S.; Staples, R.K.; Traverse, C.C.; Ellis, C.N.. "Parallel evolution of small colony variants in Burkholderia cenocepacia biofilms". Genomics (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84908430306&partnerID=MN8TOARS.
    10.1016/j.ygeno.2014.09.007
  74. Turner, P.E.; Williams, E.S.C.P.; Okeke, C.; Cooper, V.S.; Duffy, S.; Wertz, J.E.. "Antibiotic resistance correlates with transmission in plasmid evolution". Evolution 68 12 (2014): 3368-3380. http://www.scopus.com/inward/record.url?eid=2-s2.0-84914141519&partnerID=MN8TOARS.
    10.1111/evo.12537
  75. Flynn KM; Cooper TF; Moore FB; Cooper VS. "The environment affects epistatic interactions to alter the topology of an empirical fitness landscape.". (2013): http://europepmc.org/abstract/med/23593024.
    10.1371/journal.pgen.1003426
  76. Traverse CC; Mayo-Smith LM; Poltak SR; Cooper VS. "Tangled bank of experimentally evolved Burkholderia biofilms reflects selection during chronic infections.". (2013): http://europepmc.org/abstract/med/23271804.
    10.1073/pnas.1207025110
  77. Ellis CN; Schuster BM; Striplin MJ; Jones SH; Whistler CA; Cooper VS. "Influence of seasonality on the genetic diversity of Vibrio parahaemolyticus in New Hampshire shellfish waters as determined by multilocus sequence analysis.". (2012): http://europepmc.org/abstract/med/22407686.
    10.1128/AEM.07794-11
  78. Morrow JD; Cooper VS. "Evolutionary effects of translocations in bacterial genomes.". (2012): http://europepmc.org/abstract/med/23160175.
    10.1093/gbe/evs099
  79. Schuster BM; Tyzik AL; Donner RA; Striplin MJ; Almagro-Moreno S; Jones SH; Cooper VS; Whistler CA. "Ecology and genetic structure of a northern temperate Vibrio cholerae population related to toxigenic isolates.". (2011): http://europepmc.org/abstract/med/21926213.
    10.1128/AEM.00378-11
  80. Poltak SR; Cooper VS. "Ecological succession in long-term experimentally evolved biofilms produces synergistic communities.". (2011): http://europepmc.org/abstract/med/20811470.
    10.1038/ismej.2010.136
  81. Abebe E; Abebe-Akele F; Morrison J; Cooper V; Thomas WK. "An insect pathogenic symbiosis between a Caenorhabditis and Serratia.". (2011): http://europepmc.org/abstract/med/21389770.
    10.4161/viru.2.2.15337
  82. Abebe, E.; Akele, F.-A.; Morrison, J.; Cooper, V.; Kelley Thomas, W.. "An insect pathogenic symbiosis between a Caenorhabditis and Serratia". Virulence 2 2 (2011): http://www.scopus.com/inward/record.url?eid=2-s2.0-79952914164&partnerID=MN8TOARS.
  83. Cooper VS; Vohr SH; Wrocklage SC; Hatcher PJ. "Why genes evolve faster on secondary chromosomes in bacteria.". (2010): http://europepmc.org/abstract/med/20369015.
    10.1371/journal.pcbi.1000732
  84. Ellis CN; Cooper VS. "Experimental adaptation of Burkholderia cenocepacia to onion medium reduces host range.". (2010): http://europepmc.org/abstract/med/20154121.
    10.1128/AEM.01930-09
  85. Flynn KM; Vohr SH; Hatcher PJ; Cooper VS. "Evolutionary rates and gene dispensability associate with replication timing in the archaeon Sulfolobus islandicus.". (2010): http://europepmc.org/abstract/med/20978102.
    10.1093/gbe/evq068
  86. Schuster, B.M.; Perry, L.A.; Cooper, V.S.; Whistler, C.A.. "Breaking the language barrier: Experimental evolution of non-native Vibrio fischeri in squid tailors luminescence to the host". Symbiosis 51 1 (2010): 85-96. http://www.scopus.com/inward/record.url?eid=2-s2.0-77955551789&partnerID=MN8TOARS.
    10.1007/s13199-010-0074-2
  87. Flynn, K.M.; Vohr, S.H.; Hatcher, P.J.; Cooper, V.S.. "Evolutionary rates and gene dispensability associate with replication timing in the archaeon Sulfolobus islandicus.". Genome biology and evolution 2 (2010): 859-869. http://www.scopus.com/inward/record.url?eid=2-s2.0-79952200926&partnerID=MN8TOARS.
  88. Cooper VS; Carlson WA; Lipuma JJ. "Susceptibility of Caenorhabditis elegans to Burkholderia infection depends on prior diet and secreted bacterial attractants.". (2009): http://europepmc.org/abstract/med/19956737.
    10.1371/journal.pone.0007961
  89. Cooper VS. "Long-term experimental evolution in Escherichia coli. X. Quantifying the fundamental and realized niche.". (2002): http://europepmc.org/abstract/med/12199912.
    10.1186/1471-2148-2-12
  90. Cooper VS; Reiskind MH; Miller JA; Shelton KA; Walther BA; Elkinton JS; Ewald PW. "Timing of transmission and the evolution of virulence of an insect virus.". (2002): http://europepmc.org/abstract/med/12061960.
    10.1098/rspb.2002.1976
  91. Cooper VS; Bennett AF; Lenski RE. "Evolution of thermal dependence of growth rate of Escherichia coli populations during 20,000 generations in a constant environment.". (2001): http://europepmc.org/abstract/med/11430649.
    10.1554/0014-3820(2001)055[0889:EOTDOG]2.0.CO;2
  92. Cooper VS; Schneider D; Blot M; Lenski RE. "Mechanisms causing rapid and parallel losses of ribose catabolism in evolving populations of Escherichia coli B.". (2001): http://europepmc.org/abstract/med/11292803.
    10.1128/JB.183.9.2834-2841.2001
  93. Riley MS; Cooper VS; Lenski RE; Forney LJ; Marsh TL. "Rapid phenotypic change and diversification of a soil bacterium during 1000 generations of experimental evolution.". (2001): http://europepmc.org/abstract/med/11283295.
  94. Cooper, V.S.; Bennett, A.F.; Lenski, R.E.. "Evolution of thermal dependence of growth rate of escherichia coli populations during 20,000 generations in a constant environment". Evolution 55 5 (2001): 889-896. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034977941&partnerID=MN8TOARS.
  95. Riley, M.S.; Cooper, V.S.; Lenski, R.E.; Forney, L.J.; Marsh, T.L.. "Rapid phenotypic change and diversification of a soil bacterium during 1000 generations of experimental evolution". Microbiology 147 4 (2001): 995-1006. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035043486&partnerID=MN8TOARS.
  96. Cooper VS; Lenski RE. "The population genetics of ecological specialization in evolving Escherichia coli populations.". (2000): http://europepmc.org/abstract/med/11048718.
    10.1038/35037572
  97. Turner, P.E.; Cooper, V.S.; Lenski, R.E.. "Tradeoff between horizontal and vertical modes of transmission in bacterial plasmids". Evolution 52 2 (1998): 315-329. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031922777&partnerID=MN8TOARS.
  98. Elena SF; Cooper VS; Lenski RE. "Response: mechanisms of punctuated evolution.". (1996): http://europepmc.org/abstract/med/17842245.
    10.1126/science.274.5293.1749
  99. Elena SF; Cooper VS; Lenski RE. "Punctuated evolution caused by selection of rare beneficial mutations.". (1996): http://europepmc.org/abstract/med/8650581.
    10.1126/science.272.5269.1802
  100. Elena, S.F.; Cooper, V.S.; Lenski, R.E.. "Punctuated evolution caused by selection of rare beneficial mutations". Science 272 5269 (1996): 1802-1804. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030017289&partnerID=MN8TOARS.
  101. Coyne, J.A.; Charlesworth, B.; Elena, S.F.; Cooper, V.S.; Lenski, R.E.. "Mechanisms of punctuated evolution". Science 274 5293 (1996): 1748-1750. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029847072&partnerID=MN8TOARS.
    10.1126/science.274.5293.1748
Report
  1. Cooper, Vaughn. 2014. The rate and molecular spectrum of spontaneous mutations in the GC-rich multi-chromosome genome ofBurkholderia cenocepacia.
    10.1101/011841

Other

Other output
  1. The nutritional environment is sufficient to select coexisting biofilm and quorum-sensing mutants of Pseudomonas aeruginosa. 2021. Michelle R. Scribner; Amelia C. Stephens; Justin L. Huong; Anthony R. Richardson; Vaughn S. Cooper. https://doi.org/10.1101/2021.09.01.458652.
    10.1101/2021.09.01.458652
  2. SprayNPray: user-friendly taxonomic profiling of genome and metagenome contigs. 2021. Arkadiy I. Garber; Catherine R. Armbruster; Stella E. Lee; Vaughn S. Cooper; Jennifer M. Bomberger; Sean M. McAllister. https://doi.org/10.1101/2021.07.17.452725.
    10.1101/2021.07.17.452725
  3. Evolutionary divergence of the Wsp signal transduction system in ß- and ¿-proteobacteria. 2021. Collin Kessler; Eisha Mhatre; Vaughn Cooper; Wook Kim. https://doi.org/10.1101/2021.07.02.450980.
    10.1101/2021.07.02.450980
  4. Rampant prophage movement among transient competitors drives rapid adaptation during infection. 2021. Christopher W. Marshall; Erin S. Gloag; Christina Lim; Daniel J. Wozniak; Vaughn S. Cooper. https://doi.org/10.1101/2021.02.01.429245.
    10.1101/2021.02.01.429245
  5. Polygenic adaptation, clonal interference, and the evolution of mutators in experimental Pseudomonas aeruginosa populations. 2021. Katrina B. Harris; Kenneth M. Flynn; Vaughn S. Cooper. https://doi.org/10.1101/2021.01.14.426720.
    10.1101/2021.01.14.426720
  6. Genomic and chemical diversity of Bacillus subtilis secondary metabolites against plant pathogenic fungi. 2020. Heiko T. Kiesewalter; Carlos N. Lozano-Andrade; Mario Wibowo; Mikael L. Strube; Gergely Maróti; Dan Snyder; Tue Sparholt Jørgensen; et al. https://doi.org/10.1101/2020.08.05.238063.
    10.1101/2020.08.05.238063
  7. The roles of history, chance, and natural selection in the evolution of antibiotic resistance. 2020. Alfonso Santos-Lopez; Christopher W. Marshall; Allison L. Welp; Caroline Turner; Javier Rasero; Vaughn S. Cooper. https://doi.org/10.1101/2020.07.22.216465.
    10.1101/2020.07.22.216465
  8. Quorum sensing provides a molecular mechanism for evolution to tune and maintain investment in cooperation. 2020. Eric L. Bruger; Daniel J. Synder; Vaughn S. Cooper; Christopher M. Waters. https://doi.org/10.1101/2020.06.29.178467.
    10.1101/2020.06.29.178467
  9. Quantitative mapping of mRNA 3’ ends in Pseudomonas aeruginosa reveals putative riboregulators and a pervasive role for transcription termination in response to azithromycin. 2020. Salini Konikkat; Michelle R. Scribner; Rory Eutsey; N. Luisa Hiller; Vaughn S. Cooper; C. Joel McManus. https://doi.org/10.1101/2020.06.16.155515.
    10.1101/2020.06.16.155515
  10. Genotypic diversity between surgical and nasal Staphylococcus aureus isolates. 2020. Dongzhu Ma; Patrick L. Maher; Kimberly M. Brothers; Nathan J. Phillips; Deborah Simonetti; A. William Pasculle; Anthony R. Richardson; Vaughn S. Cooper; Kenneth L. Urish. https://doi.org/10.1101/2020.05.27.120436.
    10.1101/2020.05.27.120436
  11. SARS-CoV-2 genome evolution exposes early human adaptations. 2020. Erik S. Wright; Seema S. Lakdawala; Vaughn S. Cooper. https://doi.org/10.1101/2020.05.26.117069.
    10.1101/2020.05.26.117069
  12. Host adaptations in the fixLJ pathway of the Burkholderia cepacia complex increase virulence. 2020. Matthew M. Schaefers; Benjamin X. Wang; Nicole M. Boisvert; Sarah J. Martini; Sarah L. Bonney; Christopher W. Marshall; Michael T. Laub; Vaughn S. Cooper; Gregory P. Priebe. https://doi.org/10.1101/2020.05.04.070367.
    10.1101/2020.05.04.070367
  13. One gene, multiple ecological strategies: a biofilm regulator is a capacitor for sustainable diversity. 2020. Eisha Mhatre; Daniel J. Snyder; Emily Sileo; Caroline B. Turner; Sean W. Buskirk; Nico L. Fernandez; Matthew B. Neiditch; Christopher M. Waters; Vaughn S. Cooper. https://doi.org/10.1101/2020.05.02.074534.
    10.1101/2020.05.02.074534
  14. Experimental Evolution in vivo to Identify Selective Pressures During Pneumococcal Colonization. 2020. Vaughn S. Cooper; Erin Honsa; Hannah Rowe; Christopher Deitrick; Amy R. Iverson; Jonathan J. Whittall; Stephanie L. Neville; et al. https://doi.org/10.1101/2020.01.15.908590.
    10.1101/2020.01.15.908590
  15. Comprehensive analysis of horizontal gene transfer among multidrug-resistant bacterial pathogens in a single hospital. 2019. Daniel R. Evans; Marissa P. Griffith; Mustapha M. Mustapha; Jane W. Marsh; Alexander J. Sundermann; Vaughn S. Cooper; Lee H. Harrison; Daria Van Tyne. https://doi.org/10.1101/844449.
    10.1101/844449
  16. Parallel evolution of tobramycin resistance across species and environments. 2019. Michelle R. Scribner; Alfonso Santos-Lopez; Christopher W. Marshall; Christopher Deitrick; Vaughn S. Cooper. https://doi.org/10.1101/758979.
    10.1101/758979
  17. Negative frequency-dependent selection maintains coexisting genotypes during fluctuating selection. 2019. Caroline B. Turner; Sean W. Buskirk; Katrina B. Harris; Vaughn S. Cooper. https://doi.org/10.1101/729095.
    10.1101/729095
  18. Altered Nucleoprotein Binding to Influenza Virus RNA Impacts Packaging Efficiency and Replication. 2019. Valerie Le Sage; Jack P. Kanarek; Eric Nturibi; Adalena V. Nanni; Dan J. Snyder; Vaughn S. Cooper; Seema S. Lakdawala; Nara Lee. https://doi.org/10.1101/648261.
    10.1101/648261
  19. Mutations that improve the efficiency of a weak-link enzyme are rare compared to adaptive mutations elsewhere in the genome. 2019. Andrew B. Morgenthaler; Wallis R. Kinney; Christopher C. Ebmeier; Corinne M. Walsh; Daniel J. Snyder; Vaughn S. Cooper; William M. Old; Shelley D. Copley. https://doi.org/10.1101/624205.
    10.1101/624205
  20. Evolutionary pathways to antibiotic resistance are dependent upon environmental structure and bacterial lifestyle. 2019. Alfonso Santos-Lopez; Christopher W. Marshall; Michelle R. Scribner; Daniel Snyder; Vaughn S. Cooper. https://doi.org/10.1101/581611.
    10.1101/581611
  21. EvolvingSTEM: A microbial evolution-in-action curriculum that enhances learning of evolutionary biology and biotechnology. 2019. Vaughn S. Cooper; Taylor M. Warren; Abigail M. Matela; Michael Handwork; Shani Scarponi. https://doi.org/10.1101/514513.
    10.1101/514513
  22. The Pseudomonas aeruginosa Wsp pathway undergoes positive evolutionary selection during chronic infection. 2018. Erin S. Gloag; Christopher W. Marshall; Daniel Snyder; Gina R. Lewin; Jacob S. Harris; Sarah B. Chaney; Marvin Whiteley; Vaughn S. Cooper; Daniel J. Wozniak. https://doi.org/10.1101/456186.
    10.1101/456186
  23. Periodic variation of mutation rates in bacterial genomes associated with replication timing. 2017. Marcus M. Dillon; Way Sung; Michael Lynch; Vaughn S. Cooper. https://doi.org/10.1101/195818.
    10.1101/195818
  24. Parallel evolution of two clades of a major Atlantic endemic Vibrio parahaemolyticus pathogen lineage by independent acquisition of related pathogenicity islands. 2017. Xu F; Gonzalez-Escalona N; Drees KP; Sebra RP; Cooper VS; Jones SH; Whistler CA. http://europepmc.org/abstract/PPR/PPR26032.
    10.1101/155234
  25. Bacterial community profiles andVibrio parahaemolyticusabundance in individual oysters and their association with estuarine ecology. 2017. Marcinkiewicz AL; Schuster BM; Jones SH; Cooper VS; Whistler CA. http://europepmc.org/abstract/PPR/PPR27727.
    10.1101/156851
  26. Genome-wide biases in the rate and molecular spectrum of spontaneous mutations in Vibrio cholerae and Vibrio fischeri. 2016. Dillon MM; Sung W; Sebra R; Lynch M; Cooper V. http://europepmc.org/abstract/PPR/PPR29989.
    10.1101/066829
  27. Host-selected mutations converging on a global regulator drive an adaptive leap by bacteria to symbiosis. 2016. Pankey MS; Foxall RL; Ster IM; Perry LA; Schuster BM; Donner RA; Coyle MR; Cooper VS; Whistler CA. http://europepmc.org/abstract/PPR/PPR27014.
    10.1101/067025
  28. The fitness effects of spontaneous mutations nearly unseen by selection in a bacterium with multiple chromosomes. 2016. Marcus M. Dillon; Vaughn S. Cooper. https://doi.org/10.1101/060483.
    10.1101/060483
  29. Diverse phenotypic and genetic responses to short-term selection in evolving Escherichia coli populations. 2015. Dillon MM; Rouillard NP; Van Dam B; Gallet R; Cooper VS. http://europepmc.org/abstract/PPR/PPR30889.
    10.1101/027086
Distinctions

Award

2022 Elected Fellow, American Academy of Microbiology
American Society for Microbiology, United States