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José Domingos Santos is currently Associate Professor with Habilitation (Aggregation) at FEUP-Faculty of Engineering, University of Porto (2005-present) and is presently researcher of Laboratório Associado para a Química Verde, REQUIMTE-LAQV. He developed all the experimental work for his PhD at IRC in Biomedical Materials, University of London, and in 1993 obtained his PhD at FEUP, where he developed all his academic career to present. At the University he took charge of several positions, namely he was the Master Course Director, MSc. in Materials Engineering, (1994-02), Vice-Coordinator of the Materials Section of the Department of Metallurgy and Materials Engineering, (1998-99), Course Director of a five years degree on Metallurgy and Materials Engineering at the Department of Metallurgy and Materials Engineering, (1995-96), Member of the Pedagogic Council (1995-96), Member of the Executive Committee from the Department of Metallurgy and Materials Engineering, (1995-96 and 1995-1999), Permanent Member of the Metallurgy and Materials Engineering Department Council (since July 1993-present), Coordinator of the “Bioceramics and Glasses” research group at IBMC/INEB Associate Laboratory (2004-2008), Coordinator of the Biomaterials Division of the SPM-Portuguese Society of Materials (since October 1993) and Vowel of the SPEB-Portuguese Society of Biomedical Engineering (1993-1995). He has actively participated in 24 Research Projects financed by National and International institutions and was the scientific coordinator of 10 of them. He has been involved in the scientific supervision of 8 Post-Doctoral researchers, 23 PhD students and 24 MSc, all concluded. He has published 167 scientific papers in International scientific reviews of SCI, edited 3 books and 16 book chapters. h-index: 37 (without auto-cytation) He is the co-inventor of 6 registered International Patents in the Biomaterials which have resulted in very important trademarks bone grafts currently sold worldwide, namely Bonelike® and Actifuse® bone graft the latter being sold worldwide by Baxter company. He is founding member of 3 start-up companies that operate in the Health Sciences sector, in 2002 Medmat Innovation Lda, in 2005 Biosckin - Molecular and Cell Therapies SA (www.criovida.pt and www.biosckin.com) and in 2016 Genetyca-ICM SA (www.genetyca-ICM.com), as results of his I&D&I activity. He is one of the responsible for the creating the new laboratory of Biosckin SA fully dedicated to stem cells, cryopreservation and treatment. He published a great number of scientific publications on the development of Bone grafts, Biocompatibility and Clinical trials of bone graft substitutes for regenerative medicine.
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Identification

Personal identification

Full name
José Domingos Santos

Citation names

  • Santos, José

Author identifiers

Ciência ID
3B1B-2F9B-319E
ORCID iD
0000-0002-6871-9850

Email addresses

  • jdsantos@fe.up.pt (Professional)

Knowledge fields

  • Engineering and Technology - Materials Engineering - Materials Engineering
  • Engineering and Technology - Materials Engineering - Ceramics
  • Engineering and Technology - Medical Engineering - Medical Engineering
  • Engineering and Technology - Nano-technology - Nano-materials
  • Engineering and Technology - Materials Engineering - Textiles
Education
Degree Classification
1993/07/13
Concluded
 Engenharia Metalúrgica / Metallurgical Engineering (Doutoramento)
Universidade do Porto Faculdade de Engenharia, Portugal
1978/10 - 1983/07
Concluded
 Engenharia Metalúrgica / Metallurgical Engineering (Licenciatura)
Universidade do Porto Faculdade de Engenharia, Portugal
 15
Affiliation

Teaching in Higher Education

Category
Host institution 		Employer
2005/07 - Current Associate Professor (University Teacher) Universidade do Porto, Portugal
Projects

Contract

Designation Funders
2015/12 - 2020/03 iBone Therapies: Innovative Therapies for Bone Regeneration
Norte-01-0247-FEDER-003262
Principal investigator
Concluded
2016/10 - 2018 MICROdispositivos biomédicos com capacidades osteointegradoras por µPiM, com o acrónimo BEPIM III / Biomedical microdevices with osteointegrated abilities by µPiM,
POCI-01-0247-FEDER-017935
Other
2013/07 - 2015/06 Soluções avançadas de Regeneração óssea com base em Hidrógeis de dextrino-DEXGELERATION / Advanced solutions for bone regeneration based on dextrin hydrogels
QREN nº 2014/38853
Principal investigator
Universidade do Porto Faculdade de Engenharia, Portugal
Concluded
2013/09/01 - 2015/05/31 Soluções poliméricas especializadas para calçado / Specialized polymeric solutions for footware
SI IDT - 38475/2012 F3
Researcher
Concluded
2013/07 - 2015 MICROdispositivos biomédicos com capacidades osteointegradoras por µPiM, com o acrónimo BEPIM II
QREN 34128
Researcher
Universidade do Porto Faculdade de Engenharia, Portugal
Ongoing
2011/01 - 2014/01 Hybrid Nanostructured Hydrogels: Bone regeneration using Multifunctional injectable Hydrogels-Rebone
EraNet - EuroNanoMed JTC2010
Principal investigator
Universidade do Porto Faculdade de Engenharia, Portugal
Concluded
2008/01/31 - 2013/12/31 Desenvolvimento de produtos nas áreas de medicina regenerativa e de terapias celulares
Nº 1372
Principal investigator
Universidade do Porto Faculdade de Engenharia, Portugal
Concluded
2010/01 - 2013/12 Materiais bioactivos tridimensionais de Bonelike® obtidos por Powder Injection Moulding para aplicação cirúrgica ortopédica e maxilofacial - Tribone
ADI, Projecto nº 011458
Principal investigator
Universidade do Porto Faculdade de Engenharia, Portugal
Concluded
2010/04 - 2013/09 Antibacterial and Osteogenic behaviour of Modified Calcium Phosphates (MCP): In vitro and In vivo Evaluation
PTDC/SAU-BEB/103034/2008
Principal investigator
Universidade do Porto Faculdade de Engenharia, Portugal
Concluded
2009/04 - 2011/03 FatValue – Valorização de subprodutos de carnes
QREN 3491
Researcher
Universidade do Porto Faculdade de Engenharia, Portugal
2007/01 - 2010/08 Regeneração do Nervo Periférico através da utilização de Tubos-guia Biodegradáveis associados a um Sistema Celular Autólogo
PTDC/CTV/64220/2006,
Researcher
Universidade do Porto Faculdade de Engenharia, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2005 - 2008 Nova geração de Biomateriais bioactivos e bioreabsorvíveis para Cirurgia regenerativa do Tecido ósseo utilizando Biomodelização 3-D
POCTI/CTM/59091/2004
Principal investigator
Fundação para a Ciência e a Tecnologia
Concluded
2005 - 2007 Modelação e Maquinagem de Modelos bioactivos para Regeneração óssea e Libertação controlada de Fármacos - MAQBIO
70/2005/3.1B/00028/0020
Principal investigator
Agência Nacional de Inovação SA
Concluded
2004 - 2007 Revestimentos de titânio em plásticos para aplicações médicas- PLASMED
UP/CGD/12
Researcher
2004 - 2006 DLC and CVD Diamond coated Si3N4 biomaterials
POCTI/CTM/45423/2002
Researcher
Universidade do Porto Faculdade de Engenharia, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2002 - 2005 Silicon-substituted hydroxyapatite coatings for biomedical applications
POCTI/CTM/49238/2002
 Universidade do Algarve Faculdade de Ciências e Tecnologia
Concluded
2000 - 2003 Materiais Interactivos de Fosfato de cálcio preparados por Processos de Pós-Hibridização e Hibridização in situ
POCTI/35516/CTM/2000
Principal investigator
Fundação para a Ciência e a Tecnologia
Concluded
2000 - 2003 Compósitos cerâmicos Si3N4 - SiC compatíveis com Revestimentos Diamante CVD
POCTI/ CTM /35490/2000
Researcher
Fundação para a Ciência e a Tecnologia
Concluded
2000 - 2003 Novos Filmes finos Bioactivos à base de Fosfato para Biomateriais
POCTI/CTM/35478/2000
Researcher
Concluded
2000 - 2001 Desenvolvimento e Caracterização de Cerâmicos para Aplicacões médicas
P0071, P0072/ICPME/II/M
Principal investigator
Agência Nacional de Inovação SA
Concluded
1999 - 2001 Novos Compósitos de Nitreto de Silício (Si3N4) - Biovidro para Aplicações Biomédicas
Praxis XXI/C/CTM/11144
Principal investigator
Fundação para a Ciência e a Tecnologia
Concluded
1997 - 1999 Novos Sistemas de Libertação local de Fármacos para Tratamento de Periodontopatias – Liberta
Praxis XXI/PSAU/C/SAU/23/96
Researcher
Fundação para a Ciência e a Tecnologia
Concluded
1995 - 1998 Novos Revestimentos Bioactivos obtidos por Projecção por Plasma
PBICT/P/CTM/1890/95
Principal investigator
Concluded
1995 - 1998 Advance Polymer Composites and Systems for Medical Devices comprising Hydrodynamic Non-Articulating Prosthesis (HYNAP) and Composites from Naturally Occurring Polymers (CONAP)
Nº CI1 CT94 0142
Researcher
Concluded

Other

Designation Funders
2020/08 - Current "AcaVALE - high-performance functionalization of textiles"
ANI FEUP/ACATEL/2020-77142
Consulting
Agência Nacional de Inovação SA
2019/12 - Current Like-Bone - 3D structures with the morphology of human bone obtained by additive manufacturing
ANI 045284
Researcher
Agência Nacional de Inovação SA
Ongoing
Outputs

Publications

Book
  1. Rosario Pignatello; Teresa Musumeci. Biomaterials - Physics and Chemistry - New Edition. {InTech. 2018.
    10.5772/intechopen.69128
  2. Pavan Kumar, G.; Naga Sowmya, B.; Sooraj Hussain, N.; Lopes, M.A.; Santos, J.D.. Guided bone regeneration using glass-reinforced hydroxyapatite and collagen membrane in the treatment of peri-implantitis. 2014.
    10.4028/www.scientific.net/ssp.207.109
  3. Pavan Kumar, G.; Vijayakumar, R.; Naga Sowmya, B.; Sooraj Hussain, N.; Lopes, M.A.; Santos, J.D.. Treatment of a large cystic lesion in anterior maxilla using glass reinforced hydroxyapatite - A case report. 2014.
    10.4028/www.scientific.net/ssp.207.97
  4. Santos, José. Current trends on Glass and Ceramics materials. 2013.
  5. Pavan Kumar, G.; Jaya Kumar, A.; Krishnanjaneya Reddy, P.; Sooraj Hussain, N.; Lopes, M.A.; Santos, J.D.. Application of glass reinforced hydroxyapatite composite in the treatment of human intrabony periodontal angular defects - Two case reports. 2010.
    10.4028/www.scientific.net/ssp.161.93
  6. Hussain, N.S.; Santos, J.D.. Diffusion and Defect Data Pt.B: Solid State Phenomena: Preface. 2010.
    10.4028/www.scientific.net/SSP.161.-1
  7. Santos, José. Biomaterials for Bone Regenerative Medicine. 2010.
  8. Santos, José. Physics and Chemistry of Rare-Earth Ions Doped Glasses. 2008.
  9. Dias, A.G.; Lopes, M.A.; Tsuru, K.; Hayakawa, S.; Santos, J.D.; Osaka', A.. 31P MAS-NMR studies of CaO-P2O5 glass ceramics. 2006.
  10. Queiroz, A.C.; Santos, J.D.; Monteiro, F.J.. Adsorption isotherm of sodium ampicillin onto dense and porous hydroxyapatite. 2005.
  11. Dias, A.G.; Lopes, M.A.; Santos, J.D.; Fernandes, M.H.. The influence of Pre-Incubation treatment in the in vitro biological performance of degradable CaO-P2O5 Glass ceramics. 2005.
  12. Tsuru, K.; Shirosaki, Y.; Hayakawa, S.; Osaka, A.; Lopes, M.A.; Santos, J.D.; Fernandas, M.H.. In vitro biodegradability of chitosan-organosiloxane hybrid membrane. 2005.
    10.4028/www.scientific.net/kem.284-286.823
  13. Queiroz, A.C.; Santos, J.D.; Monteiro, F.J.. Porous HA scaffolds for drug releasing. 2005.
  14. Botelho, C.M.; Brooks, R.A.; Kawai, T.; Ogata, S.; Ohtsuki, C.; Best, S.M.; Lopes, M.A.; et al. In vitro analysis of protein adhesion to phase pure hydroxyapatite and silicon substituted hydroxyapatite. 2005.
  15. Queiroz, A.C.; Teixeira, S.; Santos, J.D.; Monteiro, F.J.. Production of porous hydroxyapatite with potential for controlled drug delivery. 2004.
  16. Lemos, A.F.; Santos, J.D.; Ferreira, J.M.F.. Influence of characteristics of the starting hydroxyapatite powders and of deagglomeration procedure, on rheological behaviour of HA suspensions. 2004.
  17. Dias, A.G.; Lopes, M.A.; Santos, J.D.. Protein adsorption effect on in vitro acellular biodegradation of of CaO-P2O5 Glass ceramics. 2004.
  18. Botelho, C.M.; Stokes, D.J.; Brooks, R.A.; Best, S.M.; Lopes, M.A.; Santos, J.D.; Rushton, N.; Bonfield, W.. Effect of human serum proteins on pure hydroxyapatite and silicon substituted hydroxyapatatite: AFM and SEM studies. 2004.
  19. Dias, A.G.; Costa, M.A.; Lopes, M.A.; Santos, J.D.; Fernandas, M.H.. Biological Activity of Two Glass Ceramics in the Meta- and Pyrophosphate Region: A Comparative Study. 2004.
    10.4028/www.scientific.net/kem.254-256.825
  20. Shirosaki, Y.; Tsuru, K.; Hayakawa, S.; Osaka, A.; Lopes, M.A.; Santos, J.D.; Fernandes, M.H.. In Vitro Cytocompatibility of Osteoblastic Cells Cultured on Chitosan-Organosiloxane Hybrid Membrane. 2004.
  21. Lemos, A.F.; Santos, J.D.; Ferreira, J.M.F.. New Method for the Incorporation of Soluble Bioactive Glasses to Reinforce Porous HA Structures. 2004.
  22. Botelho, C.M.; Brooks, R.A.; Best, S.M.; Lopes, M.A.; Santos, J.D.; Rushton, N.; Bonfield, W.. Biological and Physical-Chemical Characterization of Phase Pure HA and Sl-Substituted Hydroxyapatite by Different Microscopy Techniques. 2004.
  23. Silva, R.A.; Sousa, M.; Monteiro, F.J.; Barral, R.; Santos, J.D.; Lopes, M.A.. Effects of some variables on R.F. Magnetron Sputtered Hydroxyapatite Coatings on Titanium. 2004.
  24. Li, Y.; Weng, W.; Cheng, K.; Du, P.; Shen, G.; Han, G.; Lopes, M.A.; Santos, J.D.. Effect of the Solvents on the Solution Mixture Derived Polylactide/hydroxyapatite Composites. 2004.
  25. Queiroz, A.C.; Teixeira, S.; Santos, J.D.; Monteiro, F.J.. Porous Hydroxyapatite and Glass Reinforced Hydroxyapatite for Controlled Release of Sodium Ampicillin. 2004.
  26. Abreu, C.; Amaral, M.; Oliveira, F.J.; Santos, J.D.; Silva, R.F.; Gomes, J.R.. Tribological characterization of Si3N4-Bioglass biocomposites in self-mating experiments and dissimilar tests against UHMWPE. 2002.
    10.4028/www.scientific.net/kem.230-232.455
  27. Prado da Silva, M.H.; Lemos, A.F.; Ferreira, J.M.F.; Lopes, M.A.; Santos, J.D.. Production of porous biomaterials based on glass-reinforced hydroxyapatite composites. 2002.
  28. Gibson, I.R.; Hing, K.A.; Revell, P.A.; Santos, J.D.; Best, S.M.; Bonfield, W.. Enhanced in vivo response to silicate-substituted hydroxyapatite. 2002.
Book chapter
  1. Santos, Daniel; Maurício, Ana Colette; Sencadas, Vitor; Santos, José Domingos; Fernandes, Maria H.; Gomes, Pedro S.. "Spray Drying: An Overview". In Biomaterials - Physics and Chemistry - New Edition. InTech, 2018.
    10.5772/intechopen.72247
  2. Pinho, Pedro Olivério; Campos, José Miguel; Mendonça, Carla; Caseiro, Ana Rita; Santos, José Domingos; Maurício, Ana Colette; Atayde, Luís Miguel. "Clinical Application of Macroporous Ceramic to Promote Bone Healing in Veterinary Clinical Cases". In Scaffolds in Tissue Engineering - Materials, Technologies and Clinical Applications. InTech, 2017.
    10.5772/intechopen.70341
  3. Santos, José. "Luminescence and energy transfer phenomena in lanthanide ions doped phosphor and glassy materials". In Current Trends on Lanthanide Glasses and Materials, 159-189. Materials Research Forum LLC, 2017.
    10.21741/9781945291159-7
  4. Santos, José. "The Potential Clinical Application of Mesenchymal Stem Cells from the Dental Pulp (DPSCs) for Bone Regeneration". In Frontiers in Stem Cell and Regenerative Medicine Research, 21-70. BENTHAM SCIENCE PUBLISHERS, 2017.
    Published • 10.2174/9781681084770117060004
  5. Pedrosa, Sílvia Santos; Caseiro, Ana Rita; Santos, José Domingos; Maurício, Ana Colette. "Scaffolds for Peripheral Nerve Regeneration, the Importance of In Vitro and In Vivo Studies for the Development of Cell-Based Therapies and Biomaterials: State of the Art". In Scaffolds in Tissue Engineering - Materials, Technologies and Clinical Applications. InTech, 2017.
    10.5772/intechopen.69540
  6. Fernandes, MH; Caram, R; Sooraj Hussain, N; Mauricio, AC; Santos, JD. "Bonelike® graft for regenerative bone applications". 2016.
    10.1007/978-3-319-33489-9_13
  7. Pinto, P.O.; Atayde, L.M.; Campos, J.M.; Caseiro, A.R.; Pereira, T.; Mendonça, C.; Santos, J.D.; et al. "Therapeutic Strategies for Bone Regeneration: The Importance of Biomaterials Testing in Adequate Animal Models". In Advanced Composite Materials, 275-319. John Wiley & Sons, Inc., 2016.
    10.1002/9781119242666.ch6
  8. Pereira, T; Gartner, A; Amorim, I; Armada-da-, P; Gomes, R; Pereira, C; L., M; et al. "Biomaterials and Stem Cell Therapies for Injuries Associated to Skeletal Muscular Tissues". 2013.
    10.5772/53335
  9. Santos, José; Coelho, J.; Nandyala, S.H.; Gomes, P.S.; Garcia, M.P.; Lopes, M.A.; Fernandes, M.H.; Santos, J.D.; Gudi, P.K.. "Calcium phosphate ceramics in Periodontal regeneration". In Current Trends on Glass and Ceramic Materials, 116-141. BENTHAM SCIENCE PUBLISHERS, 2013.
    10.2174/9781608054527113010008
  10. Santos, José. "Calcium Phosphate-based Materials for Bone Regenerative Medicine". In Biomaterials for Bone Regenerative Medicine, 151-180. 2010.
    Published
  11. Santos, José. "Cell Adhesion and Proliferation over Zinc-Glass Reinforced Hydroxyapatite composites (Zn-GRHA)". In Biomaterials for Bone Regenerative Medicine. 2010.
  12. Santos, José. "Luminescence Spectra of Rare-earth ions doped Zinc-Boro Silicate and Lead-Bismuth-Germanate Glasses". In Physics and Chemistry of Rare-Earth Ions Doped Glasses, 225-259. 2008.
    Published
  13. Santos, José. "Optical Properties of Rare-Earth ions doped Lithium Boro Tellurite Glasses". In Physics and Chemistry of Rare-Earth Ions Doped Glasses, 261-287. 2008.
    Published
  14. Santos, José. "Biomateriais". In Biotecnologia - Fundamentos e Aplicações. 2003.
Conference abstract
  1. Gomes, PS; Botelho, C; Lopes, MA; Santos, JD; Fernandes, MH. "Effect of silicon-containing hydroxyapatite coatings on the human in vitro osteoblastic response". 2009.
    10.1016/j.bone.2009.03.464
Conference paper
  1. Joana Gomes; Jose Domingos Santos; Ana Colette Mauricio. "Regeneration of the peripheral nerve — Development and evaluation of guide tubes of biodegradable polymer". 2017.
    10.1109/enbeng.2017.7889482
  2. Caseiro, AR; Pereira, T; Bartolo, PJ; Santos, JD; Luis, AL; Mauricio, AC. "Mesenchymal Stem Cells and Biomaterials Systems - Perspectives for Skeletal Muscle Tissue Repair and Regeneration". 2015.
    10.1016/j.proeng.2015.07.014
  3. Shirosaki, Y; Hayakawa, S; Osaka, A; Lopes, MA; Santos, JD; Mauricio, AC; Geuna, S. "Preparation of inorganic-organic hybrid membrane for peripheral nerve reconstruction". 2013.
  4. Rocha, D.N.; Dias, A.G.; Santos, J.D.; Lopes, M.A.. "Microstructural analysis of degradable porous calcium phosphate glass ceramic for bone regenerationpreliminary results". 2008.
  5. Botelho, C.M.; Brooks, R.A.; Best, S.M.; Lopes, M.A.; Santos, J.D.; Rushton, N.; Bonfield, W.. "Effect of human serum proteins on silicon substituted hydroxyapatite: AFM and ESEM studies". 2004.
  6. Silva, P.L.; Santos, J.D.; Knowles, J.C.; Silva, R.F.; Monteiro, F.J.. "Fracture toughness of hydroxyapatite reinforced with P2O5-CaO glasses containing Na2O, K2O and MgO". 1996.
  7. Reis, R.L.; Cunha, A.M.; Santos, J.D.; Allan, P.S.; Bevis, M.J.. "Novel degradable biomaterials of starch based polymers reinforced with bioactive ceramics and glasses". 1996.
  8. Santos, JD; Vasconcelos, M; Reis, RL; Afonso, A; Monteiro, FJ; Hastings, GW. "Glass reinforced hydroxyapatite composites: Physical properties and preliminary histological studies in rabbits". 1994.
Journal article
  1. S.H. Nandyala; G. Hungerford; J.D. Santos; B.M. Walsh; L. Di Silvio; A. Stamboulis. "Time-resolved and excitation-emission matrix luminescence behaviour of boro-silicate glasses doped with Eu3+ ions for red luminescent application". Materials Research Bulletin 140 (2021): 111340-111340. https://doi.org/10.1016/j.materresbull.2021.111340.
    10.1016/j.materresbull.2021.111340
  2. Santos, José. "Time-resolved and fluorescence excitation-emission matrix measurements of lanthanide (Gd3+, Tb3+ and Dy3+) doped silver-zinc borate glasses". Materials Letters 273 (2020): 127935-127935. http://dx.doi.org/10.1016/j.matlet.2020.127935.
    10.1016/j.matlet.2020.127935
  3. Nuno Cruz; Maria Inês Martins; José Domingos Santos; Javier Gil Mur; joão paulo tondela. "Surface Comparison of Three Different Commercial Custom-Made Titanium Meshes Produced by SLM for Dental Applications". Materials (2020): https://www.mdpi.com/1996-1944/13/9/2177.
    10.3390/ma13092177
  4. Pinho, AC; Fonseca, AC; Caseiro, AR; Pedrosa, SS; Amorim, I; Branquinho, MV; Domingos, M; et al. "Innovative tailor made dextran based membranes with excellent non-inflammatory response: In vivo assessment". MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2020):
    10.1016/j.msec.2019.110243
  5. Pinho, AC; Branquinho, MV; Alvites, RD; Fonseca, AC; Caseiro, AR; Pedrosa, SS; Luis, AL; et al. "Dextran-based tube-guides for the regeneration of the rat sciatic nerve after neurotmesis injury". BIOMATERIALS SCIENCE (2020):
    10.1039/c9bm00901a
  6. Pereira, I; Pereira, JE; Maltez, L; Rodrigues, A; Rodrigues, C; Oliveira, M; Silva, DM; et al. "Regeneration of critical-sized defects, in a goat model, using a dextrin-based hydrogel associated with granular synthetic bone substitute". Regenerative Biomaterials (2020):
    10.1093/rb/rbaa036
  7. Campos, JM; Sousa, AC; Caseiro, AR; Pedrosa, SS; Pinto, PO; Branquinho, MV; Amorim, I; et al. "Dental pulp stem cells and Bonelike (R) for bone regeneration in ovine model". REGENERATIVE BIOMATERIALS (2019):
    10.1093/rb/rby025
  8. Pereira, I; Fraga, S; Maltez, L; Requicha, J; Guardao, L; Oliveira, J; Prada, J; et al. "In vivo systemic toxicity assessment of an oxidized dextrin-based hydrogel and its effectiveness as a carrier and stabilizer of granular synthetic bone substitutes". JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A (2019):
    10.1002/jbm.a.36683
  9. Mariana Branco; Ana R. Caseiro; Dina M. Silva; Irina Amorim; Alexandra Rêma; Sílvia S. Pedrosa; Mariana V. Branquinho; et al. "Processing, Characterization, and in Vivo Evaluation of Poly(l-lactic acid)-Fish Gelatin Electrospun Membranes for Biomedical Applications". ACS Applied Bio Materials 1 2 (2018): 226-236. https://doi.org/10.1021%2Facsabm.8b00023.
    10.1021/acsabm.8b00023
  10. C. Fidalgo; M. A. Rodrigues; T. Peixoto; J. V. Lobato; J. D. Santos; M. A. Lopes. "Development of asymmetric resorbable membranes for guided bone and surrounding tissue regeneration". Journal of Biomedical Materials Research Part A 106 8 (2018): 2141-2150. https://doi.org/10.1002%2Fjbm.a.36420.
    10.1002/jbm.a.36420
  11. Campos, JM; Sousa, AC; Pinto, PO; Ribeiro, J; França, ML; Caseiro, AR; Branquinho, MV; et al. "Application of Bonelike® as synthetic bone graft in orthopaedic and oral surgery in veterinary clinical cases". Biomaterials Research (2018):
    10.1186/s40824-018-0150-x
  12. Ksouri, D; Khireddine, H; Aksas, A; Valente, T; Bir, F; Slimani, N; Cabal, B; Torrecillas, R; Santos, JD. "Synthesis of ternary bioactive glass derived aerogel and xerogel: Study of their structure and bioactivity". Nova Biotechnologica et Chimica (2018):
    10.2478/nbec-2018-0016
  13. Caseiro, AR; Ivanova, G; Pedrosa, SS; Branquinho, MV; Georgieva, P; Barbosa, PP; Santos, JD; et al. "Human umbilical cord blood plasma as an alternative to animal sera for mesenchymal stromal cells in vitro expansion - A multicomponent metabolomic analysis". PLOS ONE (2018):
    10.1371/journal.pone.0203936
  14. Daniel Santos; Dina M. Silva; Pedro S. Gomes; Maria H. Fernandes; José D. Santos; Vitor Sencadas. "Multifunctional PLLA-ceramic fiber membranes for bone regeneration applications". Journal of Colloid and Interface Science 504 (2017): 101-110. https://doi.org/10.1016%2Fj.jcis.2017.05.032.
    10.1016/j.jcis.2017.05.032
  15. Daniel Santos; Cristina O. Correia; Dina M. Silva; Pedro S. Gomes; Maria H. Fernandes; José D. Santos; Vitor Sencadas. "Incorporation of glass-reinforced hydroxyapatite microparticles into poly(lactic acid) electrospun fibre mats for biomedical applications". Materials Science and Engineering: C 75 (2017): 1184-1190. https://doi.org/10.1016%2Fj.msec.2017.03.007.
    10.1016/j.msec.2017.03.007
  16. Joao Torres; Manuel Gutierres; Luis Atayde; Paulo Cortez; M. Ascenção Lopes; J. Domingos Santos; Abel T. Cabral; Carola F. van Eck. "The benefit of bone marrow concentrate in addition to a glass-reinforced hydroxyapatite for bone regeneration: An in vivo ovine study". Journal of Orthopaedic Research 35 6 (2017): 1176-1182. https://doi.org/10.1002%2Fjor.22800.
    10.1002/jor.22800
  17. Jorge Ribeiro; Ana Rita Caseiro; Tiago Pereira; Paulo Alexandre Armada-da-Silva; Isabel Pires; Justina Prada; Irina Amorim; et al. "Evaluation of PVA biodegradable electric conductive membranes for nerve regeneration in axonotmesis injuries: the rat sciatic nerve animal model". Journal of Biomedical Materials Research Part A 105 5 (2017): 1267-1280. https://doi.org/10.1002%2Fjbm.a.35998.
    10.1002/jbm.a.35998
  18. A.R. Caseiro; T. Pereira; J. Ribeiro; J.D. Santos; I. Amorim; A.L. Luís; A.C. Maurício. "Neuro-muscular regeneration using scaffolds with mesenchymal stem cells (MSCs) isolated from human umbilical cord Wharton's jelly". Ciência & Tecnologia dos Materiais 29 1 (2017): e135-e139. https://doi.org/10.1016%2Fj.ctmat.2016.04.003.
    10.1016/j.ctmat.2016.04.003
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  137. Lopes, MA; Monteiro, FJ; Santos, JD; Lopes, M.A.; Monteiro, F.J.; Santos, J.D.. "Glass-reinforced hydroxyapatite composites: fracture toughness and hardness dependence on microstructural characteristics". BIOMATERIALS 20 21 (1999): 2085-2090. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033231746&partnerID=MN8TOARS.
    10.1016/s0142-9612(99)00112-x
  138. Ferraz, MP; Fernandes, MH; Cabral, AT; Santos, JD; Monteiro, FJ; Ferraz, M.P.; Fernandes, M.H.; et al. "In vitro growth and differentiation of osteoblast-like human bone marrow cells on glass reinforced hydroxyapatite plasma-sprayed coatings". JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE 10 9 (1999): 567-576. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033198788&partnerID=MN8TOARS.
    10.1023/a:1008924516146
  139. Ferraz, M.P.; Knowles, J.C.; Olsen, I.; Monteiro, F.J.; Santos, J.D.. "Flow cytometry analysis of effects of glass on response of osteosarcoma cells to plasma-sprayed hydroxyapatite/CaO-P2O5 coatings". Journal of Biomedical Materials Research 47 4 (1999): 603-611. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031573504&partnerID=MN8TOARS.
    10.1002/(sici)1097-4636(19991215)47:4<603::aid-jbm18>3.0.co;2-6
  140. Lopes, M.A.; Monteiro, F.J.; Santos, J.D.; Lopes, MA; Monteiro, FJ; Santos, JD. "Glass-reinforced hydroxyapatite composites: Secondary phase proportions and densification effects on biaxial bending strength". Journal of Biomedical Materials Research 48 5 (1999): 734-740. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032868650&partnerID=MN8TOARS.
    10.1002/(SICI)1097-4636(1999)48:5<734::AID-JBM20>3.0.CO;2-2
  141. Lopes MA; Santos JD; Monteiro FJ; Knowles JC. "Glass-reinforced hydroxyapatite: a comprehensive study of the effect of glass composition on the crystallography of the composite.". (1998): http://europepmc.org/abstract/med/9457554.
    10.1002/(sici)1097-4636(199802)39:2<244::aid-jbm11>3.0.co;2-d
  142. Lopes, M.A.; Knowles, J.C.; Kuru, L.; Santos, J.D.; Monteiro, F.J.; Olsen, I.; Lopes, MA; et al. "Flow cytometry for assessing biocompatibility". Journal of Biomedical Materials Research 41 4 (1998): 649-656. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032531299&partnerID=MN8TOARS.
    10.1002/(SICI)1097-4636(19980915)41:4<649::AID-JBM17>3.0.CO;2-9
  143. Silva, P.L.; Santos, J.D.; Monteiro, F.J.; Knowles, J.C.. "Adhesion and microstructural characterization of plasma-sprayed hydroxyapatite/glass ceramic coatings onto Ti-6Al-4V substrates". Surface and Coatings Technology 102 3 (1998): 191-196. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032047796&partnerID=MN8TOARS.
    10.1016/s0257-8972(97)00576-8
  144. Jha, L.J.; Best, S.M.; KNOWLES, J.C.; Rehman, I; Santos, J.D; Bonfield, W.. "Preparation and characterization of fluoride-substituted apatites". Journal of Materials Science: Materials in Medicine 8 4 (1997): 185-191. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031124259&partnerID=MN8TOARS.
    10.1023/A:1018531505484
  145. Santos, J. D.; Silva, P. L.; Knowles, J. C.; Talal, S.; Monteiro, F. J.. "Reinforcement of hydroxyapatite by adding P2O5-CaO glasses with Na2O, K2O and MgO". Journal of Materials Science: Materials in Medicine 7 3 (1996): 187-189. http://dx.doi.org/10.1007/bf00121259.
    10.1007/bf00121259
  146. Jha, L.J.; Santos, J.D.; Knowles, J.C.. "Characterisation of the Apatite layer formation on P2O5-CaO, P2O5-CaO-Na2O and P2O5-CaO-Na2O-Al2O3 Glass Hydroxyapatite composites". Journal of Biomedical Materials Research 31 4 (1996): 481-486. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030222031&partnerID=MN8TOARS.
    10.1002/(sici)1097-4636(199608)31:4<481::aid-jbm7>3.0.co;2-h
  147. Knowles, J.C.; Talal, S.; Santos, J.D.. "Sintering effects in a glass reinforced hydroxyapatite". Biomaterials 17 14 (1996): 1437-1442. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030199532&partnerID=MN8TOARS.
    10.1016/0142-9612(96)87287-5
  148. Santos, J.D.; Jha, L.J.; Monteiro, F.J.. "In vitro calcium phosphate formation on SiO2-Na2O-CaO-P2O5 glass reinforced hydroxyapatite composite: A study by XPS analysis". Journal of Materials Science: Materials in Medicine 7 3 (1996): 181-185. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030106254&partnerID=MN8TOARS.
    10.1007/BF00121258
  149. Afonso, A.; Santos, J.D.; Vasconcelos, M.; Branco, R.; Cavalheiro, J.. "Granules of osteoapatite and glass-reinforced hydroxyapatite implanted in rabbit tibiae". Journal of Materials Science: Materials in Medicine 7 8 (1996): 507-510. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029666749&partnerID=MN8TOARS.
    10.1007/bf00705433
  150. SANTOS, JD; JHA, LJ; MONTEIRO, FJ. "SURFACE MODIFICATIONS OF GLASS-REINFORCED HYDROXYAPATITE COMPOSITES". BIOMATERIALS (1995):
    10.1016/0142-9612(95)91124-h
  151. Santos, J.D.; Jha, L.J.; Monteiro, F.J.. "Surface modifications of glass-reinforced hydroxyapatite composites". Biomaterials 16 7 (1995): 521-526. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029294502&partnerID=MN8TOARS.
    10.1016/0142-9612(95)91124-H
  152. Santos, J.D.; Reis, R.L.; Monteiro, F.J.; Knowles, J.C.; Hastings, G.W.. "Liquid phase sintering of hydroxyapatite by phosphate and silicate glass additions: structure and properties of the composites". Journal of Materials Science: Materials in Medicine 6 6 (1995): 348-352. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029311049&partnerID=MN8TOARS.
    10.1007/bf00120303
  153. Santos, J.D.; Knowles, J.C.; Reis, R.L.; Monteiro, F.J.; Hastings, G.W.. "Microstructural characterization of glass-reinforced hydroxyapatite composites". Biomaterials 15 1 (1994): 5-10. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028087242&partnerID=MN8TOARS.
    10.1016/0142-9612(94)90188-0
  154. Tudor, A.M.; Melia, C.D.; Davies, M.C.; Anderson, D.; Hastings, G.; Morrey, S.; Domingos-Sandos, J.; Barbosa, M.. "The analysis of biomedical hydroxyapatite powders and hydroxyapatite coatings on metallic medical implants by near-IR Fourier transform Raman spectroscopy". Spectrochimica Acta Part A: Molecular Spectroscopy 49 5-6 (1993): 675-680. http://www.scopus.com/inward/record.url?eid=2-s2.0-0000650098&partnerID=MN8TOARS.
    10.1016/0584-8539(93)80089-s
  155. Santos, JDS; Monteiro, FJ. "Wear behaviour of stainless steel after al2o3 plasma spraying for biomedical applications". Surface Engineering (1990):
    10.1179/sur.1990.6.3.209

Intellectual property

Patent
  1. Santos, José. 2018. "Photopolymerized Biodegradable Copolymer Formulations for Biomedical Applications". Portugal.
  2. Santos, José. 2012. "Hydroxyapatite and Bioglass pellets, Production process and Applications of thereof". Portugal.
  3. Santos, José. 2009. "Hydroxyapatite, Biocompatible Glass and Silicon-based Bone Substitute, Production Process and Applications of Thereof". Portugal.
  4. Santos, José. 2000. "Sintered Hydroxyapatite Compositions and Method for the Preparation Thereof". Portugal.
  5. Santos, José. 1998. "Revestimentos Cerâmicos com Bio-actividade e Composição Variáveis Destinados a Aplicações Biomédicas em Próteses e Implantes". Portugal.
  6. Santos, José. 1998. "Silicon-Substituted Apatites and Process for the Preparation Thereof". Portugal.

Other

Other output
  1. Assessment of the environmental impacts of medical devices: a review. 2020. Sousa, AC; Veiga, A; Mauricio, AC; Lopes, MA; Santos, JD; Neto, B.
    10.1007/s10668-020-01086-1
  2. The Potential Clinical Application of Mesenchymal Stem Cells from the Dental Pulp (DPSCs) for Bone Regeneration. 2017. Ana Rita Caseiro; Rui Alvites; Sílvia Santos Pedrosa; José Miguel Campos; Inês Leal Reis; José Domingos Santos; Carla Mendonça; Luís Miguel Atayde; Ana Colette Maurício. https://doi.org/10.2174%2F9781681084770117060004.
    10.2174/9781681084770117060004
  3. Scaffolds for Peripheral Nerve Regeneration, the Importance of In Vitro and In Vivo Studies for the Development of Cell-Based Therapies and Biomaterials: State of the Art. 2017. Sílvia Santos Pedrosa; Ana Rita Caseiro; José Domingos Santos; Ana Colette Maurício. https://doi.org/10.5772%2Fintechopen.69540.
    10.5772/intechopen.69540
  4. Clinical Application of Macroporous Ceramic to Promote Bone Healing in Veterinary Clinical Cases. 2017. Pedro Olivério Pinho; José Miguel Campos; Carla Mendonça; Ana Rita Caseiro; José Domingos Santos; Ana Colette Maurício; Luís Miguel Atayde. https://doi.org/10.5772%2Fintechopen.70341.
    10.5772/intechopen.70341
  5. Trends in Mesenchymal Stem Cells' Applications for Skeletal Muscle Repair and Regeneration. Progress in Stem Cell Transplantation. 2015. A.R. Caseiro; T. Pereira; P.J. Bártolo; J.D. Santos; A.L. Luís; A.C. Maurício; Caseiro, A.R.; et al. https://doi.org/10.5772%2F60919.
    10.5772/60919
  6. Microanalysis of Bioactive Samarium Doped Glass-Reinforced Hydroxyapatite. 2015. Morais, DS; Coelho, J; Lopes, MA; Ferraz, MP; Gomes, P; Fernandes, MH; Santos, JD; Hussain, NS.
    10.1017/s1431927615013963
  7. Bonelike Graft for Regenerative Bone Applications. Surface Engineered Surgical Tools and Medical Devices. 2007. Santos, José. http://dx.doi.org/10.1007/978-0-387-27028-9_13.
    10.1007/978-0-387-27028-9_13
Activities

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2020/01 - Current Association of 3D printing and Cellular therapies for regenerative Medicine
Co-supervisor of Ana Catarina Soares de Sousa
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2020 - Current Fabrico aditivo de Materiais biocerâmicos para Aplicações dentárias
Supervisor of António José Vieira de Melo Esteves
Universidade do Porto Faculdade de Engenharia, Portugal
2019 - Current Caracterização in vivo do microbioma formado em superfícies tratadas e totalmente maquinadas de implantes de Titânio
Co-supervisor of António José de Sousa da Silva
Instituto Universitário Egas Moniz, Portugal
2019 - Current Desenvolvimento de estruturas 3D customizadas para regeneração óssea por fabrico aditivo / Development of costumized 3D structures for bone regeneration by additive manufactoring
Co-supervisor of Pedro Corte-Real Soares
Universidade do Porto Faculdade de Engenharia, Portugal
2014 - Current Estudos de citocompatibilidade e de biocompatilidade de dispositivos médicos para regeneração do tecido ósseo: Estudos in vivo em Medicina Veterinária
Co-supervisor of Pedro Olivério Monteiro Sanches Pinto
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2014 - 2020 Cell-based Therapies in Regenerative Medicine - The Therapeutic Potential of Umbilical Cord and Dental Pulp Derived Stem/Stromal Cells
Co-supervisor of Ana Rita Caseiro Santos
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2018 - 2019/07 Fabricação de membranas de policaprolactona por electrospinning para medicina regenerativa
Co-supervisor of Bianca Beatriz Basso
 Mestrado Integrado em Engenharia Metalúrgica e de Materiais (Master)
Universidade do Porto Faculdade de Engenharia, Portugal
2018 - 2019/07 Development of customized 3D structures for bone regeneration by Additive Manufacturing
Supervisor of Filipa Leal
 Mestrado integrado em Bioengenharia (Master)
Universidade do Porto Faculdade de Engenharia, Portugal
2018 - 2019/07 Processamento e Caracterização de biocerâmicos obtidos por Fabrico aditivo para Regeneração óssea
Supervisor of Ana Azevedo
 Mestrado Integrado em Engª Metalúrgica e Materiais (Master)
Universidade do Porto Faculdade de Engenharia, Portugal
2018 - 2019/03 3D Modeling Applied to the Manufacture of Personalized Bioceramic Medical Devices
Co-supervisor of Maria Inês Mora Martins
 Mestrado Integrado em BioEngenharia (MIB) (Master)
Universidade do Porto Faculdade de Engenharia, Portugal
2015 - 2019 Development of Biomaterials and Cell Therapies for Bone Regeneration
Co-supervisor of José Miguel Franco Esteves de Campos
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2017 - 2018/07 Desenvolvimento de Implantes Dentários Customizados por Selective Laser Melting
Supervisor of Joana Abreu Silva
 Mestrado Integrado em Engenharia Metalurgia e de Materiais (Master)
Universidade do Porto Faculdade de Engenharia, Portugal
2017 - 2018/07 Synthesis and characterization of PLLA microparticles loaded Chitosan hydrogel to promote Gingival repair
Supervisor of Marlene Rajão
 Mestrado em Engenharia Biomédica (Master)
Universidade do Porto Faculdade de Engenharia, Portugal
2017 - 2018/03 Avaliação e Ensaios pré-clínicos de Bonelike® para Regeneração óssea em Defeitos Não-críticos.
Supervisor of Ana Catarina Soares de Sousa
 Mestrado Integrado em Bioengenharia (Master)
Universidade do Porto Faculdade de Engenharia, Portugal
2013 - 2018 Pheripheral nerve regeneration – Development and evaluation of Biodegradable polymers guide-tube
Co-supervisor of Ana Catarina Pinho
2016 - 2017/03 Additive Manufacturing of Custom-Fit Orthoses for the Upper Limb
Supervisor of Ana Faria
 Mestrado Integrado em Bioengenharia (Master)
Universidade do Porto Faculdade de Engenharia, Portugal
2015 - 2016/10 Desenvolvimento e Caracterização de membranas de PLA com gelatina de peixe por Electrospinning para Regeneração nervosa
Supervisor of Mariana Branco Marinheiro Ferreira de Sousa
 Mestrado em Engenharia Biomédica (Master)
Universidade do Porto Faculdade de Engenharia, Portugal
2009 - 2016 Development of an injectable dextrin hydrogel for Bone regeneration
Co-supervisor
2014 - 2015/10 Desenvolvimento de um hidrogel de ácido hialurónico e de dextrino para expansão de células estaminais mesenquimatosas (MSCs) indiferenciadas
Co-supervisor of Alberto Carvalho
 Mestrado Integrado em Engenharia Biomédica (Master)
Universidade do Minho, Portugal
2014 - 2015/07 Multifunctional Electrospun Fiber membranes and Composites associated to Bone Grafts for Bone regeneration
Supervisor of Daniel Santos
 Mestrado Integrado em Bioengenharia (Master)
Universidade do Porto Faculdade de Engenharia, Portugal
2014 - 2015/07 Development of an Injectable modified Calcium phosphate (Bonelike) - Dextrin hydrogel biomaterial for Bone regeneration
Supervisor of Antero Jesus da Silva Oliveira
Universidade do Porto Faculdade de Engenharia, Portugal
2009 - 2015 Utilização de uma Hidroxiapatite modificada associada a Stem cells no tratamento de Fracturas transtrocantéricas (colo do fémur)
Co-supervisor of João Manuel C. Ferreira Torres
2013 - 2014/07 Regeneration of the Peripheral Nerve – Development and evaluation of guide tubes of biodegradable polymer
Supervisor of Joana Maria Silva Gomes
 Mestrado Integrado em Bioengenharia (Master)
Universidade do Porto Faculdade de Engenharia, Portugal
2013 - 2014/07 Development of a Polymeric matrix based on Hyaluronic Acid and Dextrin Hydrogels for the Expansion of Undifferentiated Mesenchymal Stem Cells
Supervisor of Joana Maria Azevedo Martins
 Mestrado Integrado em Bioengenharia (Master)
Universidade do Porto Faculdade de Engenharia, Portugal
2009 - 2014 Aplicação de Enxertos vasculares artificiais de Polímeros Biodegradáveis num Modelo animal
Co-supervisor of Nuno Miguel Lourenço Alexandre
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2009 - 2014 Substitutos ósseos para Regeneração do Tecido Ósseo: Estudos in vivo e Futuras Aplicações Clínicas em Medicina Veterinária
Co-supervisor of Luís Miguel Atayde
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2008 - 2013 Association of Biomaterials and Mesenchymal stem cells from Wharton´s Jelly of human Umbilical cord for promotion of Pheripheral nerve regeneration: a Functional and Morphological study
Co-supervisor of Andréa Louise Gärtner
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2011 - 2012/07 Development and Characterisation of a Glass-Reinforced Hydroxyapatite composite with Antibacterial Properties
Supervisor of Soraia Margarida Silva Teixeira Fernandes
 Mestrado Integrado em Bioengenharia (Master)
Universidade do Porto Faculdade de Engenharia, Portugal
2011 - 2012/07 Desenvolvimento e Caracterização de um Substituto ósseo injectável para Regeneração do Tecido ósseo
Supervisor of Vânia Rodrigues
 Mestrado em Eng Biomédica (MEB) (Master)
Universidade do Porto Faculdade de Engenharia, Portugal
2010 - 2011/07 Development, Physicochemical and Biological characterisation of Bioactive Three-Dimensional (3D) matrices for Bone Tissue Regeneration
Supervisor of Ana Rita Ferreira
 Mestrado Integrado em Bioengenharia (Master)
Universidade do Porto Faculdade de Engenharia, Portugal
2007 - 2011 Contribuição para o Estudo da Regeneração do Nervo Periférico
Co-supervisor of Maria João Simões
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2006 - 2011 Modified Calcium Phosphates used for Bone Tissue Regeneration: In Vivo Studies in an Ovine Model
Co-supervisor of Paulo Pegado Cortez
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2005 - 2011 Cirurgia Experimental para o estudo da Regeneração nervosa de Nervos Periféricos e sua Transposição para Casos Clínicos
Co-supervisor of Jorge Manuel Rodrigues,
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2009 - 2010/10 Bonelike® Associated to Stem Cells for the Regeneration of the Bone Tissue
Supervisor of Ana Cláudia da Costa Lopes
 Mestrado em Engª Biomédica (Master)
Universidade do Porto Faculdade de Engenharia, Portugal
2008 - 2010 Optimised calcium-phosphate for keratoprosthesis applications
Supervisor of Lívia Joana dos Santos
 Pós–Doutoramento (Other)
Universidade do Porto Faculdade de Engenharia, Portugal
2006 - 2010 Utilização do Bonelike® para Regeneração de Tecidos: Relação Angiogénese-Osteogénese
Co-supervisor of J. M. Silva Marques
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2009 - 2009/12 Desenvolvimento de uma Instalação-Piloto para a preparação de hidroxiapatite de Fase Pura
Supervisor of Carlos Gonçalves
 Mestrado em Engenharia Biomédica (Master)
Universidade do Porto Faculdade de Engenharia, Portugal
2008 - 2009/09 Produção e Caracterização de Macroporosos de Bonelike® pelo Método de Replicação de Espumas de Poliuretano
Supervisor of Hugo Belarmino Tavares
 Mestrado Integrado em Engenharia Metalúrgica e de Materiais (Master)
Universidade do Porto Faculdade de Engenharia, Portugal
2007 - 2008/05 In vitro Osteogenic performance of Bonelike® modulated by tetracyclines
Supervisor of Pedro Sousa Gomes
Universidade do Porto Faculdade de Engenharia, Portugal
2007 - 2008/03 Hidroxiapatite modificada com silício para aplicações biomédicas
Supervisor of Ana Catarina Campos
2005 - 2008 Synthetic Bone Grafts as Carriers for Bone Morphogenetic Proteins (BMPs): Applications in Reconstructive Surgery
Supervisor of Yuki Shirosaki
 Pós-Doutoramento (Other)
Universidade do Porto Faculdade de Engenharia, Portugal
2005 - 2008 Fabrico e Caracterização de Biocerâmicos macroporosos modificados para Regeneração de tecidos
Co-supervisor of Isabel Alexandra Lemos
Universidade do Porto Faculdade de Engenharia, Portugal
2002 - 2008 Preparation of Glasses for bone repair by Pre- and Post-doping with Elements and Molecules of Biological functionality
Supervisor of Nandyala Sooraj Hussain
 Pós-Doutoramento (Other)
Universidade do Porto Faculdade de Engenharia, Portugal
2006 - 2007 Biological modelation of Calcium phosphate composites for Reconstructive surgery
Supervisor of Cláudia Manuela Botelho
 Pós-Doutoramento (Other)
Universidade do Porto Faculdade de Engenharia, Portugal
2006 - 2007 Preparation and characterization of Porous 3D Bonelike® structure through Biomodelling and 3D Machining techniques
Supervisor of Marta Laranjeira
 Mestrado em Engenharia Biomédica (Master)
Universidade do Porto Faculdade de Engenharia, Portugal
2004 - 2007 Estudos in vivo de Substitutos ósseos para Cirurgia maxilofacial
Co-supervisor of José Ventura Lobato
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2004 - 2007 Estudo sobre o Comportamento Biológico in vitro e in vivo de um nova Hidroxiapatite modificada
Co-supervisor of Manuel Gutierres
Universidade do Porto Faculdade de Medicina, Portugal
2003 - 2007 Nanocrystalline Diamond Coatings for Biomedical applications
Co-supervisor of Margarida Isabel dos Santos Amaral
2002 - 2005 Hidroxiapatite Modificada com Silício para Aplicações Biomédicas
Supervisor of Cláudia Manuela Botelho
Universidade do Porto Faculdade de Engenharia, Portugal
2002 - 2005 Biodegradable Glass Ceramics for Bone Regeneration
Supervisor of Anabela Gregório Dias
Universidade do Porto Faculdade de Engenharia, Portugal
2000 - 2004 Bioactive and Biodegradable Ceramics with Adequate Morphologies for Controlled Drug Delivery
Supervisor of Ana Carla Queiroz
Universidade do Porto Faculdade de Engenharia, Portugal
1998 - 2002 Revestimentos Cerâmicos Bioactivos para Biomateriais
Co-supervisor of Paula Luísa Silva
Universidade do Porto Faculdade de Engenharia, Portugal
2000 - 2001 Modificação superficial de Compósitos cerâmicos por Processos de Silanização destinados a Aplicações médicas
Supervisor of Marcelo Prado
 Pós-Doutoramento (Other)
Universidade do Porto Faculdade de Engenharia, Portugal
1997 - 2001 Modulação farmacológica da Interacção Tecido ósseo-Biomateriais: Estudos in vitro
Co-supervisor of Maria João Coelho
Universidade do Porto Faculdade de Medicina Dentária, Portugal
1999 - 2000 Novos compósitos de Si3N4-biovidros para aplicações biomédicas
Supervisor of Maria Ascensão Lopes
 Pós-Doutoramento (Other)
Universidade do Porto Faculdade de Engenharia, Portugal
1996 - 2000 Revestimentos Cerâmicos Bioactivos: Estudos in vitro das Interacções com o Ambiente Local
Co-supervisor of Maria Pia Ferraz
Universidade do Porto Faculdade de Engenharia, Portugal
1998 - 1999 P2O5-CaO Glasses and Glass Ceramics for Biomedical Applications
Supervisor of Yong Zhang
 Pós– Doutoramento (Other)
Universidade do Porto Faculdade de Engenharia, Portugal
1998 - 1999 Compósitos de matriz de Si3N4 para Aplicações Biomédicas
Supervisor of Serafim Melo Oliveira
 Mestrado em Engenharia de Materiais (Master)
Universidade do Porto Faculdade de Engenharia, Portugal
1998 - 1999 Compósitos de matriz de Si3N4 para Aplicações Biomédicas
Supervisor of Serafim Melo Oliveira
 Mestrado em Engenharia de Materiais (Master)
Universidade do Porto Faculdade de Engenharia, Portugal
1996 - 1999 Glass reinforced hydroxyapatite composites: Structural, Physicochemical characterisation and Biological performance
Supervisor of Maria Ascensão Lopes
Universidade do Porto Faculdade de Engenharia, Portugal
1994 - 1996 Analysis of the Substitutions of Hydroxyapatite Obtained by Control of Precipitation Conditions Aiming at Biomedical Applications
Supervisor of Lakhan J. Jha
 Pós–Doutoramento (Other)
Universidade do Porto Faculdade de Engenharia, Portugal
Distinctions

Award

2009 Prémio incentivo à Investigação
Universidade do Porto Faculdade de Engenharia, Portugal
2008 Prémio Incentivo à Investigação
Universidade do Porto Faculdade de Engenharia, Portugal
2006 Prémio Professor Carlos Lima 2006
Sociedade Portuguesa de Ortopedia e Traumatologia, Portugal
2005 Prémio Depuy Johnson&Johnson

Other distinction

2016 Diploma de Reconhecimento Científico
Universidade do Porto Faculdade de Engenharia, Portugal