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I am a goal-oriented and self-driven professional with a passion for problem-solving. My career in nanobiotechnology has equipped me with a solid foundation in key techniques and extensive laboratory experience. I have a proven ability to adapt to new projects and teams, conduct independent research, and effectively communicate complex ideas and results. My natural curiosity and holistic approach enable me to understand projects at both the molecular/nanoscale level and in terms of their broader applications and strategic impact.
Identification

Personal identification

Full name
Rui Pedro Oliveira Silva

Citation names

  • Oliveira-Silva, Rui

Author identifiers

Ciência ID
3D18-6B6F-110A
ORCID iD
0000-0001-6172-0413

Telephones

Mobile phone
  • (+351) 916245884 (Personal)

Addresses

  • Rua Damião de Góis, n3 4esq, Encosta do Sol, 2650-325, Amadora, Amadora, Portugal (Personal)

Websites

Knowledge fields

  • Engineering and Technology - Materials Engineering - Materials Engineering
  • Engineering and Technology - Nano-technology
  • Medical and Health Sciences - Medical Biotechnology - Health-Related Biotechnology

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Proficiency (C2) Proficiency (C2) Advanced (C1) Proficiency (C2) Advanced (C1)
Spanish; Castilian Intermediate (B1) Advanced (C1) Intermediate (B1) Advanced (C1) Upper intermediate (B2)
Education
Degree Classification
2023/02/01 - 2024/07/31
Concluded
 Development of 4D wireless thermometry to target tumor ablation (Pós-doutoramento)
Universidade de Aveiro, Portugal
2016/09/01 - 2022/11/30
Concluded
 Biotechnology and Biosciences (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal

Technische Universiteit Eindhoven, Netherlands
"Nanoparticle-based (bio)sensors: Blowing tailwinds of information to Wellness and Healthcare" (THESIS/DISSERTATION)
 Pass with Distinction
2022/05/23 - 2022/05/26
Concluded
 EATRIS PLUS - Summer School on Personalized Medicine (Outros)
Infarmed Autoridade Nacional do Medicamento e Produtos de Saúde IP, Portugal
2015/03/03 - 2015/07/14
Concluded
 COHITEC 2015 (Pós-Graduação)
Universidade do Porto Porto Business School, Portugal
2012/12
Concluded
 Master in Biotechnology (Mestrado)
Major in Molecular Biotechnology
Universidade de Aveiro, Portugal
"Aplicação de Nanopartículas Magnéticas para caracterização de Proteases" (THESIS/DISSERTATION)
2011/10/27 - 2011/11/04
Concluded
 Motivation and Leadership (Outros)
Universidade de Aveiro Associação para a Formação Profissional e Investigação, Portugal
2007/09/01 - 2011/06/30
Concluded
 Biotecnologia (Licenciatura)
Universidade de Aveiro, Portugal
Affiliation

Science

Category
Host institution 		Employer
2023/02/01 - 2024/07/31 Postdoc (Research) Universidade de Aveiro, Portugal
Universidade de Aveiro CICECO, Portugal
2021/01/01 - 2021/09/30 Research Assistant (Research) Universidade de Lisboa Instituto Superior Técnico, Portugal
2015/03/01 - 2016/08/31 Research Assistant (Research) Universidade de Aveiro, Portugal
Universidade de Aveiro CICECO, Portugal
2014/10/01 - 2014/12/31 Research Assistant (Research) Universidade de Aveiro, Portugal
Universidade de Aveiro CICECO, Portugal
2014/05/01 - 2014/07/31 Research Assistant (Research) Universidade de Aveiro, Portugal
Universidade de Aveiro CICECO, Portugal
2013/09/01 - 2014/02/28 Research Assistant (Research) Universidade de Aveiro, Portugal
Universidade de Aveiro Unidade de Investigação de Química Orgânica Produtos Naturais e Agroalimentares, Portugal

Others

Category
Host institution 		Employer
2016/09/01 - 2022/11/30 Ph.D. Universidade de Lisboa Instituto Superior Técnico, Portugal
Technische Universiteit Eindhoven, Netherlands
(...)
Projects

Grant

Designation Funders
2024/08/01 - Current A Gold Nanosensor for Single-Molecule Detection of RNA Biomarkers in a Miniaturized Microscope
2022.04076.PTDC
Integration into Research Grant Fellow
Fundação para a Ciência e a Tecnologia
Ongoing
2023/02/01 - 2024/07/31 Development of 4D wireless thermometry to target tumor ablation
PTDC/NAN-MAT/3901/2020
Integration into Research Grant Fellow
Fundação para a Ciência e a Tecnologia
Concluded
2016/09/01 - 2022/11/30 Nanomaterials-based Biosensors: Blowing tailwinds of information towards Wellness and Healthcare
PD/BD/116850/2016
PhD Student Fellow
Universidade de Lisboa Instituto Superior Técnico, Portugal

Universidade de Lisboa Instituto de Bioengenharia e Biociências, Portugal

Technische Universiteit Eindhoven, Netherlands
Fundação para a Ciência e a Tecnologia
Concluded
2018/07/01 - 2021/09/30 Desenvolvimento e aplicação de nanomagnetes e ferrofluidos com variação on-to-off da magnetização em torno da temperatura ambiente
POCI-01-0145-FEDER-029460
Integration into Research Grant Fellow
Fundação para a Ciência e a Tecnologia
Concluded
2018/09/01 - 2020/12/31 Funcionalização de Materiais à Base de Celulose com Biomoléculas e Nanoestruturas Utilizando Estratégias de Reconhecimento Biomolecular
PTDC/CTM-CTM/30790/2017
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2016/06/01 - 2019/05/31 Desenvolvimento de fontes de arrefecimento controladas remotamente para uma nanotermodinâmica aplicada
PTDC/CTM-NAN/4511/2014
Integration into Research Grant Fellow
Fundação para a Ciência e a Tecnologia
Concluded
2014/05/01 - 2014/07/31 Metabolic profiling: a novel tool for evaluation of the toxicological and biological effects of nanomaterials
PTDC/SAU-TOX/120953/2010
Integration into Research Grant Fellow
Fundação para a Ciência e a Tecnologia
2012/01/01 - 2013/05/31 Nanomaterials to capture polluting metallic ions: efficiency, Selectivity and recycling
PTDC/CTM-NAN/120668/2010
Integration into Research Grant Fellow
Fundação para a Ciência e a Tecnologia
Concluded

Contract

Designation Funders
2013/06/01 - 2014/11/30 Desenvolvimento de uma plataforma em nanoescala para o enriquecimento de proteases
EXPL/BBB-BEP/0317/2012
Universidade de Aveiro, Portugal

Universidade de Aveiro Unidade de Investigação de Química Orgânica Produtos Naturais e Agroalimentares, Portugal

Universidade do Porto Faculdade de Medicina Dentária, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Book
  1. Cova, M.; Oliveira-Silva, R.; Ferreira, J.A.; Ferreira, R.; Amado, F.; Daniel-Da-Silva, A.L.; Vitorino, R.. Glycoprotein enrichment method using a selective magnetic nano-probe platform (Mnp) functionalized with lectins. 2014.
    10.1007/978-1-4939-1872-0_5
Conference paper
  1. Fantoni, A.; Fernandes, M.; Vygranenko, Y.; Vieira, M.; Oliveira-Silva, R.P.; Prazeres, D.M.F.; Ribeiro, A.P.C.; Alegria, E.C.B.A.. "Optical properties of metal nanoparticles embedded in amorphous silicon analysed using discrete dipole approximation". 2018.
    10.1117/12.2289983
Conference poster
  1. A. Rita Silva-Santos; Oliveira-Silva, Rui; Pedro Miguel Neves Ribeiro Paulo; Prazeres, Duarte Miguel F.. "Single-step purification of ssDNA scaffolds using affinity magnetic beads for DNA-origami biomanufacturing". Paper presented in ISPPP 2021, 2021.
Journal article
  1. Botequim, David; Oliveira-Silva, Rui; Serra, Vanda Vaz; Zijlstra, Peter; Prazeres, Duarte; Paulo, Pedro. "Nanoplasmonics for Enhanced Fluorescence Detection of Nucleic Acids: from Fundamentals to Boosting Cancer Management". Advanced NanoBiomed Research (2025):
    Accepted
  2. Oliveira-Silva, Rui; Yuyang Wang; Sjoerd W. Nooteboom; Duarte M. F. Prazeres; Pedro M. R. Paulo; Peter Zijlstra. "Single-Particle Plasmon Sensor to Monitor Proteolytic Activity in Real Time". ACS Applied Optical Materials (2023): https://doi.org/10.1021/acsaom.3c00226.
    10.1021/acsaom.3c00226
  3. Silva-Santos, A. Rita; Oliveira-Silva, Rui; Sousa Rosa, Sara; Paulo, Pedro M. R.; Prazeres, Duarte Miguel F.. "Affinity-Based Magnetic Particles for the Purification of Single-Stranded DNA Scaffolds for Biomanufacturing DNA-Origami Nanostructures". ACS Applied Nano Materials 4 12 (2021): 14169-14177. http://dx.doi.org/10.1021/acsanm.1c03623.
    10.1021/acsanm.1c03623
  4. Oliveira-Silva, Rui; Sousa-Jerónimo, Mariana; Botequim, David; Silva, Nuno J. O.; Paulo, Pedro; Prazeres, Duarte. Corresponding author: Oliveira-Silva, Rui. "Monitoring Proteolytic Activity in Real Time: A New World of Opportunities for Biosensors". Trends in Biochemical Sciences (2020): http://dx.doi.org/10.1016/j.tibs.2020.03.011.
    10.1016/j.tibs.2020.03.011
  5. Oliveira-Silva, Rui. "Density Gradient Selection of Colloidal Silver Nanotriangles for Assembling Dye-Particle Plasmophores". Nanomaterials (2019): http://dx.doi.org/10.3390/nano9060893.
    10.3390/nano9060893
  6. Oliveira-Silva, Rui; Pereira, Rute A.; Silva, Fábio M.; Gaspar, Vítor M.; Ibarra, Alfonso; Millán, Ángel; Sousa, Filipa L.; Mano, João F.; Silva, Nuno J. O.. "Temperature-responsive nanomagnetic logic gates for cellular hyperthermia". Materials Horizons 6 3 (2019): 524-530. http://dx.doi.org/10.1039/c8mh01510d.
    10.1039/c8mh01510d
  7. Fantoni, A.; Fernandes, M.; Vygranenko, Y.; Louro, P.; Vieira, M.; Silva, R. P. O.; Texeira, D.; et al. "Analysis of metallic nanoparticles embedded in thin film semiconductors for optoelectronic applications". Optical and Quantum Electronics 50 6 (2018): http://dx.doi.org/10.1007/s11082-018-1523-z.
    10.1007/s11082-018-1523-z
  8. Matias, I.A.S.; Ribeiro, A.P.C.; Oliveira-Silva, R.P.; Prazeres, D.M.F.; Martins, L.M.D.R.S.. "Gold nanotriangles as selective catalysts for cyclohexanol and cyclohexanone production". Applied Sciences (Switzerland) 8 12 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85058626544&partnerID=MN8TOARS.
    10.3390/app8122655
  9. Bastos, A.R.; Vicente, C.M.S.; Oliveira-Silva, R.; Silva, N.J.O.; Tacão, M.; da Costa, J.P.; Lima, M.; André, P.S.; Ferreira, R.A.S.. "Integrated optical Mach-Zehnder interferometer based on organic-inorganic hybrids for photonics-on-a-chip biosensing applications". Sensors (Switzerland) 18 3 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85044093260&partnerID=MN8TOARS.
    10.3390/s18030840
  10. Carrola, J.; Bastos, V.; Jarak, I.; Oliveira-Silva, R.; Malheiro, E.; Daniel-da-Silva, A.L.; Oliveira, H.; et al. "Metabolomics of silver nanoparticles toxicity in HaCaT cells: structure–activity relationships and role of ionic silver and oxidative stress". Nanotoxicology 10 8 (2016): 1105-1117. http://www.scopus.com/inward/record.url?eid=2-s2.0-84965036143&partnerID=MN8TOARS.
    10.1080/17435390.2016.1177744
  11. Trindade, F.; Amado, F.; Oliveira-Silva, R.P.; Daniel-da-Silva, A.L.; Ferreira, R.; Klein, J.; Faria-Almeida, R.; Gomes, P.S.; Vitorino, R.. "Toward the definition of a peptidome signature and protease profile in chronic periodontitis". Proteomics - Clinical Applications 9 9-10 (2015): 917-927. http://www.scopus.com/inward/record.url?eid=2-s2.0-84942988037&partnerID=MN8TOARS.
    10.1002/prca.201400191
  12. Daniel-da-Silva, A.L.; Salgueiro, A.M.; Creaney, B.; Oliveira-Silva, R.; Silva, N.J.O.; Trindade, T.. "Carrageenan-grafted magnetite nanoparticles as recyclable sorbents for dye removal". Journal of Nanoparticle Research 17 7 (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84937438117&partnerID=MN8TOARS.
    10.1007/s11051-015-3108-0
  13. Oliveira-Silva, R.; Da Costa, J.P.; Vitorino, R.; Daniel-Da-Silva, A.L.. "Magnetic chelating nanoprobes for enrichment and selective recovery of metalloproteases from human saliva". Journal of Materials Chemistry B 3 2 (2015): 238-249. http://www.scopus.com/inward/record.url?eid=2-s2.0-84916898625&partnerID=MN8TOARS.
    10.1039/c4tb01189a
  14. da Costa, J.P.; Oliveira-Silva, R.; Daniel-da-Silva, A.L.; Vitorino, R.. "Bionanoconjugation for Proteomics applications - An overview". Biotechnology Advances 32 5 (2014): 952-970. http://www.scopus.com/inward/record.url?eid=2-s2.0-84904767694&partnerID=MN8TOARS.
    10.1016/j.biotechadv.2014.04.013
Preprint
  1. Soeiro, Joana F.; Pereira, Rute A.; Oliveira-Silva, Rui; Sousa, Filipa L.; Gaspar, Vítor M.; Mano, João F.; Millán, Ángel; et al. "Simultaneous near infrared photothermal therapy and temperature mapping by magnetic resonance in 3D cell aggregates loaded with Fe3Se4 nanoparticles". 2024. http://dx.doi.org/10.26434/chemrxiv-2024-7w4xg.
    10.26434/chemrxiv-2024-7w4xg
Thesis / Dissertation
  1. "Nanoparticle-based (Bio)sensors: blowing tailwinds of information to wellness and healthcare". PhD, 2022. https://scholar.tecnico.ulisboa.pt/records/DIRQR-boGUnOipgOOfZ-13dk1tZD7FmJPdtJ.
  2. "Aplicação de Nanopartículas Magnéticas para caracterização de Proteases". Master, 2012. https://ria.ua.pt/bitstream/10773/11003/1/7125.pdf.

Intellectual property

Patent
  1. Oliveira-Silva, Rui; Silva, Nuno J. O.. 2019. "PROBE ELEMENT AND METHODS FOR SEPARATION AND SENSING OF ANALYTES CONTROLLED BY TEMPERATURE".
    Granted/Issued
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2024/06/18 Simultaneous photothermal therapy and temperature mapping by magnetic resonance in 3D Cellular Assemblies loaded with Fe3Se4 nanoparticles NanoSeries
RSC (Lisbon, Portugal)
2024/04/19 Ask me if you can: Nanobiotechnology in healthcare Annual International (Bio)Medical Students meeting (AIMS)
(Lisbon, Portugal)
2023/04/15 Ask me if you can: (bio)sensors and nanobiotechnology in healthcare Annual International Medical Students meeting (AIMS)
(Lisbon, Portugal)
2023/03/29 Nanoparticles-based (Bio)sensors: Blowing Tailwinds of Information to Wellness and Healthcare Jornadas da Ciência
(Braga, Portugal)
2023/02/08 O desenvolvimento de nanosensores para terapêutica - Nanobiotecnologia PubHD
(Lisbon, Portugal)
2022/10/07 A single-particle plasmon sensor to monitor proteolytic activity in real-time Nintec Science Days
(Lisbon, Portugal)
2021 A Single Particle LSPR Biosensor for Thrombin Activity Determination in Real-time NanoPT
(Online, Portugal)
2019/06/16 Monitorization of cellular hyperthermia using iron selenide nanoplatelets as temperature-responsive nanomagnetic logic gates Nano Today 6th Edition
Nano Today - Elsevier (Lisbon, Portugal)
2019/05/30 Temperature-responsive magnetic logic gates in cellular hyperthermia process NanoSpain
(Barcelona, Spain)
2019/03/14 Temperature-switch nanomagnetic logic gates for cellular hyperthermia 6th International Conference on Multifunctional, Hybrid and Nanomaterials
(Sitges, Spain)

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2016/09/01 - 2017/02/28 Bioenterpreunership Empreendedorismo em Bioengenharia (Licenciatura) Universidade de Lisboa Instituto Superior Técnico, Portugal

Mentoring / Tutoring

Topic Student name
2020/03/01 - 2020/10/27 Correlative Microscopy of Single Metallic Particles Tom Sistermans
2017/09/01 - 2018/12/13 Development and application of functionalized polyoxometalates as fluorescents-tags in biosensing applications José Silvares
2017/02/01 - 2017/06/30 Carbon Dots as sensors for metal leaching in catalysis Marta D. Silva; Teresa S.C. Rosa;
2017/02/01 - 2017/06/30 Synthesis and characterization of Carbon Dots Catarina B.B.B. Gonçalves; Ana S.M.L. Dias
2015/06/01 - 2016/08/31 Biosensors for the early diagnosis of acute myocardial infarction (AMI) using Surface Enhanced Raman Spectroscopy Diogo Mendonça
Distinctions

Award

2019 Student Travel award
2019 Student Travel award