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Identification

Personal identification

Full name
Costanza Emanueli

Author identifiers

Ciência ID
3E19-BED2-96EF
ORCID iD
0000-0002-2392-0702
Education
Degree Classification
1995/09/01 - 1999/08/31
Concluded
 Pharmacology and Experimental Medicine (multi-centric PhD programme Universities of Catania, Cagliari and Florence) (Doutoramento)
Università degli Studi di Firenze, Italy
1988/09/01 - 1992/08/31
Concluded
 BSc Degree in Biological Sciences (Licenciatura)
Università degli Studi di Firenze, Italy
 110/110 magna cum laude
Affiliation

Positions / Appointments

Category
Host institution 		Employer
2018/04/01 - Current BHF Professor in cardiovascular science (National Heart and Lung Institute) Imperial College London, United Kingdom
2010/01/01 - 2018/03/31 British Heart Foundation Chair of Cardiovascular Science, Bristol Heart Institute, University of Bristol, National Heart & Lung Institute, Imperial College London University of Bristol Faculty of Medical and Veterinary Sciences, United Kingdom
2008/09/01 - 2010/08/31 Reader of Research in Experimental Cardiovascular Medicine (Bristol Heart Institute ) University of Bristol Faculty of Medical and Veterinary Sciences, United Kingdom
2005/09/01 - 2008/08/31 British Heart Foundation Basic Science Senior Lecturer (Bristol Heart Insitute) University of Bristol Faculty of Medical and Veterinary Sciences, United Kingdom
2003/09/01 - 2005/08/31 National Institute of Biostructures & Biosystems, Alghero: Alghero, IT National Institute of Biostructures & Biosystems, Italy
Projects

Grant

Designation Funders
2020/12 - 2025/11 Exosomes in ischaemic heart disease accompanied with diabetes mellitus: from pathogenic mediators to novel therapeutic agents
RG/20/9/35101
 British Heart Foundation
2021/06/01 - 2025/05/31 BHF Chair in Cardiovascular Science
CH/15/1/31199
Principal investigator
British Heart Foundation, United Kingdom
Ongoing
2019/10/01 - 2023/09/30 Doctoral Training Grant (DTG) to provide funding for 1 PhD studentship.
FS/19/57/34894D
Supervisor
British Heart Foundation, United Kingdom
 UK Research and Innovation
Ongoing
2020/11 - 2022/10 "COVIRNA" (A diagnostic test to improve surveillance and care of COVID-19 patients)
101016072 — COVIRNA
 European Commission
2018/04/01 - 2021/12/31 Doctoral Training Grant (DTG) to provide funding for 1 PhD studentship
NE/I528769/1
Supervisor
Diabetes UK, United Kingdom
 UK Research and Innovation
Concluded
2015/06 - 2020/05 Chair in Cardiovascular Science
CH/15/1/31199
 BHF Centre of Research Excellence
2015/05 - 2020/04 MicroRNAs in ischaemic heart disease and diabetes mellitus: from cardiac surgery to basic science (and back?)
RG/15/5/31446
 British Heart Foundation
2014/02 - 2019/12 MicroRNA-Based Therapeutic Strategies in Vascular Disease (MIRVAD)
13 CVD 02
 Fondation Leducq
Outputs

Publications

Book
  1. Howard, L.; Caporali, A.; Shantikumar, S.; Emanueli, C.. MicroRNAs in Vascular Remodeling and Repair. 2015.
  2. Emanueli, C.; Meloni, M.; Hasan, W.; Habecker, B.A.. The biology of neurotrophins: Cardiovascular function. 2014.
    10.1007/978-3-642-45106-5_12
  3. Alessandri, G.; Emanueli, C.; Madeddu, P.. Genetically engineered stem cell therapy for tissue regeneration. 2004.
    10.1196/annals.1302.023
Journal article
  1. Hassan Abdulrazzak; Pilar Ruiz-Lozano; Costanza Emanueli. "Epicardium-derived extracellular vesicles: a promising avenue for cardiac regeneration". Cardiovascular Research 118 2 (2022): 350-352. https://doi.org/10.1093/cvr/cvab223.
    10.1093/cvr/cvab223
  2. Emma Louise Robinson; Costanza Emanueli; Fabio Martelli; Yvan Devaux. "Leveraging non-coding RNAs to fight cardiovascular disease: the EU-CardioRNA network". European Heart Journal (2021): https://doi.org/10.1093/eurheartj/ehab326.
    10.1093/eurheartj/ehab326
  3. Maarten Vanhaverbeke; Ritienne Attard; Monika Bartekova; Soumaya Ben-Aicha; Timo Brandenburger; David de Gonzalo-Calvo; Costanza Emanueli; et al. "Peripheral blood RNA biomarkers for cardiovascular disease from bench to bedside: a position paper from the EU-CardioRNA COST action CA17129". Cardiovascular Research (2021): https://doi.org/10.1093/cvr/cvab327.
    10.1093/cvr/cvab327
  4. Aaron Scott; Lorena Sueiro Ballesteros; Marston Bradshaw; (¿¿¿); Ann Power; James Lorriman; John Love; et al. "In Vivo Characterization of Endogenous Cardiovascular Extracellular Vesicles in Larval and Adult Zebrafish". Arteriosclerosis, Thrombosis, and Vascular Biology (2021): https://doi.org/10.1161/ATVBAHA.121.316539.
    10.1161/ATVBAHA.121.316539
  5. Lina Badimon; Emma L Robinson; Amela Jusic; Irina Carpusca; Leon J deWindt; Costanza Emanueli; Péter Ferdinandy; et al. "Cardiovascular RNA markers and artificial intelligence may improve COVID-19 outcome: a position paper from the EU-CardioRNA COST Action CA17129". Cardiovascular Research 117 8 (2021): 1823-1840. https://doi.org/10.1093/cvr/cvab094.
    10.1093/cvr/cvab094
  6. Emma L Robinson; Andrew H Baker; Mairi Brittan; Ian McCracken; G Condorelli; C Emanueli; P K Srivastava; et al. "Dissecting the transcriptome in cardiovascular disease". Cardiovascular Research (2021): https://doi.org/10.1093/cvr/cvab117.
    10.1093/cvr/cvab117
  7. Sveva Bollini; Costanza Emanueli. "To serve and protect: a new heart patrolling and recycling role for macrophages". Cardiovascular Research 117 2 (2021): e17-e20. https://doi.org/10.1093/cvr/cvaa356.
    10.1093/cvr/cvaa356
  8. Helen L Spencer; Rachel Sanders; Mounia Boulberdaa; Marco Meloni; Amy Cochrane; Ana-Mishel Spiroski; Joanne Mountford; et al. "The LINC00961 transcript and its encoded micropeptide, small regulatory polypeptide of amino acid response, regulate endothelial cell function". Cardiovascular Research 116 12 (2020): 1981-1994. https://doi.org/10.1093/cvr/cvaa008.
    10.1093/cvr/cvaa008
  9. Gomes, C.P.D.C.; Schroen, B.; Kuster, G.M.; Robinson, E.L.; Ford, K.; Squire, I.B.; Heymans, S.; et al. "Regulatory RNAs in Heart Failure". Circulation 141 4 (2020): 313-328. http://www.scopus.com/inward/record.url?eid=2-s2.0-85078439069&partnerID=MN8TOARS.
    10.1161/CIRCULATIONAHA.119.042474
  10. Stoica, S.C.; Dorobantu, D.M.; Vardeu, A.; Biglino, G.; Ford, K.L.; Bruno, D.V.; Zakkar, M.; et al. "MicroRNAs as potential biomarkers in congenital heart surgery". Journal of Thoracic and Cardiovascular Surgery (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85064745999&partnerID=MN8TOARS.
    10.1016/j.jtcvs.2019.03.062
  11. Moscarelli, M.; Fiorentino, F.; Suleiman, M.-S.; Emanueli, C.; Reeves, B.C.; Punjabi, P.P.; Angelini, G.D.. "Remote ischaemic preconditioning in isolated aortic valve and coronary artery bypass surgery: A randomized trial". European Journal of Cardio-thoracic Surgery 55 5 (2019): 905-912. http://www.scopus.com/inward/record.url?eid=2-s2.0-85068537456&partnerID=MN8TOARS.
    10.1093/ejcts/ezy404
  12. da Costa Gomes, C.P.; Ágg, B.; Andova, A.; Arslan, S.; Baker, A.; Barteková, M.; Beis, D.; et al. "Catalyzing transcriptomics research in cardiovascular disease: The CardioRNA COST action CA17129". Non-coding RNA 5 2 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85069910260&partnerID=MN8TOARS.
    10.3390/NCRNA5020031
  13. Ford, K.L.; Anwar, M.; Heys, R.; Ahmed, E.M.; Caputo, M.; Game, L.; Reeves, B.C.; et al. "Optimisation of laboratory methods for whole transcriptomic RNA analyses in human left ventricular biopsies and blood samples of clinical relevance". PLoS ONE 14 3 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85063008335&partnerID=MN8TOARS.
    10.1371/journal.pone.0213685
  14. Chen, H.; Moreno-Moral, A.; Pesce, F.; Devapragash, N.; Mancini, M.; Heng, E.L.; Rotival, M.; et al. "Author Correction: WWP2 regulates pathological cardiac fibrosis by modulating SMAD2 signaling (Nature Communications, (2019), 10, 1, (3616), 10.1038/s41467-019-11551-9)". Nature Communications 10 1 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85071967308&partnerID=MN8TOARS.
    10.1038/s41467-019-12060-5
  15. Sophocleous, F.; Biffi, B.; Milano, E.G.; Bruse, J.; Caputo, M.; Rajakaruna, C.; Schievano, S.; et al. "Aortic morphological variability in patients with bicuspid aortic valve and aortic coarctation". European Journal of Cardio-thoracic Surgery 55 4 (2019): 704-713. http://www.scopus.com/inward/record.url?eid=2-s2.0-85063270542&partnerID=MN8TOARS.
    10.1093/ejcts/ezy339
  16. Besnier, M.; Shantikumar, S.; Anwar, M.; Dixit, P.; Chamorro-Jorganes, A.; Sweaad, W.; Sala-Newby, G.; et al. "miR-15a/-16 Inhibit Angiogenesis by Targeting the Tie2 Coding Sequence: Therapeutic Potential of a miR-15a/16 Decoy System in Limb Ischemia". Molecular Therapy - Nucleic Acids 17 (2019): 49-62. http://www.scopus.com/inward/record.url?eid=2-s2.0-85067292678&partnerID=MN8TOARS.
    10.1016/j.omtn.2019.05.002
  17. Dang, Z.; Avolio, E.; Albertario, A.; Sala-Newby, G.B.; Thomas, A.C.; Wang, N.; Emanueli, C.; Madeddu, P.. "Nerve growth factor gene therapy improves bone marrow sensory innervation and nociceptor-mediated stem cell release in a mouse model of type 1 diabetes with limb ischaemia". Diabetologia 62 7 (2019): 1297-1311. http://www.scopus.com/inward/record.url?eid=2-s2.0-85064833552&partnerID=MN8TOARS.
    10.1007/s00125-019-4860-y
  18. Machado, M.J.C.; Boardman, R.; Riu, F.; Emanueli, C.; Benest, A.V.; Bates, D.O.. "Enhanced notch signaling modulates unproductive revascularization in response to nitric oxide-angiopoietin signaling in a mouse model of peripheral ischemia". Microcirculation 26 6 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85067491366&partnerID=MN8TOARS.
    10.1111/micc.12549
  19. Chen, H.; Moreno-Moral, A.; Pesce, F.; Devapragash, N.; Mancini, M.; Heng, E.L.; Rotival, M.; et al. "WWP2 regulates pathological cardiac fibrosis by modulating SMAD2 signaling". Nature Communications 10 1 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85070403874&partnerID=MN8TOARS.
    10.1038/s41467-019-11551-9
  20. Alvino, V.V.; Fernández-Jiménez, R.; Rodriguez-Arabaolaza, I.; Slater, S.; Mangialardi, G.; Avolio, E.; Spencer, H.; et al. "Transplantation of allogeneic pericytes improves myocardial vascularization and reduces interstitial fibrosis in a swine model of reperfused acute myocardial infarction". Journal of the American Heart Association 7 2 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85040924925&partnerID=MN8TOARS.
    10.1161/JAHA.117.006727
  21. Besnier, M.; Gasparino, S.; Vono, R.; Sangalli, E.; Facoetti, A.; Bollati, V.; Cantone, L.; et al. "miR-210 Enhances the Therapeutic Potential of Bone-Marrow-Derived Circulating Proangiogenic Cells in the Setting of Limb Ischemia". Molecular Therapy 26 7 (2018): 1694-1705. http://www.scopus.com/inward/record.url?eid=2-s2.0-85048447268&partnerID=MN8TOARS.
    10.1016/j.ymthe.2018.06.003
  22. Descamps, B.; Saif, J.; Benest, A.V.; Biglino, G.; Bates, D.O.; Chamorro-Jorganes, A.; Emanueli, C.. "BDNF (Brain-Derived Neurotrophic Factor) promotes embryonic stem cells differentiation to endothelial cells via a molecular pathway, including MicroRNA-214, EZH2 (Enhancer of Zeste Homolog 2), and eNOS (Endothelial Nitric Oxide Synthase)". Arteriosclerosis, Thrombosis, and Vascular Biology 38 9 (2018): 2117-2125. http://www.scopus.com/inward/record.url?eid=2-s2.0-85055596448&partnerID=MN8TOARS.
    10.1161/ATVBAHA.118.311400
  23. Rodriguez-Martinez, A.; Posma, J.M.; Ayala, R.; Neves, A.L.; Anwar, M.; Petretto, E.; Emanueli, C.; et al. "MWASTools: An R/bioconductor package for metabolome-wide association studies". Bioinformatics 34 5 (2018): 890-892. http://www.scopus.com/inward/record.url?eid=2-s2.0-85042940639&partnerID=MN8TOARS.
    10.1093/bioinformatics/btx477
  24. Shanmuganathan, M.; Vughs, J.; Noseda, M.; Emanueli, C.. "Exosomes: Basic biology and technological advancements suggesting their potential as ischemic heart disease therapeutics". Frontiers in Physiology 9 NOV (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85057008629&partnerID=MN8TOARS.
    10.3389/fphys.2018.01159
  25. MacAskill, M.G.; Saif, J.; Condie, A.; Jansen, M.A.; MacGillivray, T.J.; Tavares, A.A.S.; Fleisinger, L.; et al. "Robust Revascularization in Models of Limb Ischemia Using a Clinically Translatable Human Stem Cell-Derived Endothelial Cell Product". Molecular Therapy 26 7 (2018): 1669-1684. http://www.scopus.com/inward/record.url?eid=2-s2.0-85046168520&partnerID=MN8TOARS.
    10.1016/j.ymthe.2018.03.017
  26. Coumans, F.A.W.; Brisson, A.R.; Buzas, E.I.; Dignat-George, F.; Drees, E.E.E.; El-Andaloussi, S.; Emanueli, C.; et al. "Methodological guidelines to study extracellular vesicles". Circulation Research 120 10 (2017): 1632-1648. http://www.scopus.com/inward/record.url?eid=2-s2.0-85019953265&partnerID=MN8TOARS.
    10.1161/CIRCRESAHA.117.309417
  27. Biglino, G.; Caputo, M.; Rajakaruna, C.; Angelini, G.; van Rooij, E.; Emanueli, C.. "Modulating microRNAs in cardiac surgery patients: Novel therapeutic opportunities?". Pharmacology and Therapeutics 170 (2017): 192-204. http://www.scopus.com/inward/record.url?eid=2-s2.0-85007473627&partnerID=MN8TOARS.
    10.1016/j.pharmthera.2016.11.004
  28. Dumas, M.-E.; Emanueli, C.. "Circulating micrornas to predict the risk for metabolic diseases in the general population?". Diabetes 66 3 (2017): 565-567. http://www.scopus.com/inward/record.url?eid=2-s2.0-85019562909&partnerID=MN8TOARS.
    10.2337/dbi16-0072
  29. Dykes, I.M.; Emanueli, C.. "Transcriptional and Post-transcriptional Gene Regulation by Long Non-coding RNA". Genomics, Proteomics and Bioinformatics 15 3 (2017): 177-186. http://www.scopus.com/inward/record.url?eid=2-s2.0-85020080988&partnerID=MN8TOARS.
    10.1016/j.gpb.2016.12.005
  30. Sasso, L.; Hosamuddin, H.; Emanueli, C.. "Extracellular vesicles at the cross-line between basic science and clinical needs". Microcirculation 24 1 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85010877162&partnerID=MN8TOARS.
    10.1111/micc.12333
  31. Gomes, C.P.C.; Spencer, H.; Ford, K.L.; Michel, L.Y.M.; Baker, A.H.; Emanueli, C.; Balligand, J.-L.; Devaux, Y.. "The Function and Therapeutic Potential of Long Non-coding RNAs in Cardiovascular Development and Disease". Molecular Therapy - Nucleic Acids 8 (2017): 494-507. http://www.scopus.com/inward/record.url?eid=2-s2.0-85029328956&partnerID=MN8TOARS.
    10.1016/j.omtn.2017.07.014
  32. Beltrami, C.; Besnier, M.; Shantikumar, S.; Shearn, A.I.U.; Rajakaruna, C.; Laftah, A.; Sessa, F.; et al. "Human Pericardial Fluid Contains Exosomes Enriched with Cardiovascular-Expressed MicroRNAs and Promotes Therapeutic Angiogenesis". Molecular Therapy 25 3 (2017): 679-693. http://www.scopus.com/inward/record.url?eid=2-s2.0-85016255446&partnerID=MN8TOARS.
    10.1016/j.ymthe.2016.12.022
  33. Aday, S.; Zoldan, J.; Besnier, M.; Carreto, L.; Saif, J.; Fernandes, R.; Santos, T.; et al. "Synthetic microparticles conjugated with VEGF165 improve the survival of endothelial progenitor cells via microRNA-17 inhibition". Nature Communications 8 1 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85030330994&partnerID=MN8TOARS.
    10.1038/s41467-017-00746-7
  34. Munasinghe, P.E.; Riu, F.; Dixit, P.; Edamatsu, M.; Saxena, P.; Hamer, N.S.J.; Galvin, I.F.; et al. "Type-2 diabetes increases autophagy in the human heart through promotion of Beclin-1 mediated pathway". International Journal of Cardiology 202 (2016): 13-20. http://www.scopus.com/inward/record.url?eid=2-s2.0-84942252892&partnerID=MN8TOARS.
    10.1016/j.ijcard.2015.08.111
  35. Emanueli, C.; Shearn, A.I.U.; Laftah, A.; Fiorentino, F.; Reeves, B.C.; Beltrami, C.; Mumford, A.; et al. "Coronary artery-bypass-graft surgery increases the plasma concentration of exosomes carrying a cargo of cardiac microRNAs: An example of exosome trafficking out of the human heart with potential for cardiac biomarker discovery". PLoS ONE 11 4 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84966930089&partnerID=MN8TOARS.
    10.1371/journal.pone.0154274
  36. Caporali, A.; Miscianinov, V.; Saif, J.; Emanueli, C.. "MicroRNA transport in cardiovascular complication of diabetes". Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids 1861 12 (2016): 2111-2120. http://www.scopus.com/inward/record.url?eid=2-s2.0-84956683640&partnerID=MN8TOARS.
    10.1016/j.bbalip.2016.01.010
  37. Zakkar, M.; Angelini, G.D.; Emanueli, C.. "Regulation of vascular endothelium inflammatory signalling by shear stress". Current Vascular Pharmacology 14 2 (2016): 181-186. http://www.scopus.com/inward/record.url?eid=2-s2.0-84958969164&partnerID=MN8TOARS.
    10.2174/1570161114666151202205139
  38. Fortunato, T.M.; Beltrami, C.; Emanueli, C.; De Bank, P.A.; Pula, G.. "Platelet lysate gel and endothelial progenitors stimulate microvascular network formation in vitro: Tissue engineering implications". Scientific Reports 6 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84965138518&partnerID=MN8TOARS.
    10.1038/srep25326
  39. Sahoo, S.; Emanueli, C.. "Exosomes in diabetic cardiomyopathy: The next-generation therapeutic targets?". Diabetes 65 10 (2016): 2829-2831. http://www.scopus.com/inward/record.url?eid=2-s2.0-84989170622&partnerID=MN8TOARS.
    10.2337/dbi16-0041
  40. Boulberdaa, M.; Scott, E.; Ballantyne, M.; Garcia, R.; Descamps, B.; Angelini, G.D.; Brittan, M.; et al. "A role for the long noncoding RNA SENCR in commitment and function of endothelial cells". Molecular Therapy 24 5 (2016): 978-990. http://www.scopus.com/inward/record.url?eid=2-s2.0-84962703776&partnerID=MN8TOARS.
    10.1038/mt.2016.41
  41. Caputo, M.; Skerritt, C.; Emanueli, C.. "Circulating micrornas as new biomarkers of ischaemia/reperfusion injury during cardiac surgery". Cardiology (Switzerland) 130 4 (2015): 234-236. http://www.scopus.com/inward/record.url?eid=2-s2.0-84925422987&partnerID=MN8TOARS.
    10.1159/000375482
  42. Mushtaq, S.; Ali, T.; Gul, M.; Javed, Q.; Emanueli, C.; Murtaza, I.. "Insulin over expression induces heart abnormalities via reactive oxygen species regulation, might be step towards cardiac hypertrophy". Cellular and Molecular Biology 61 1 (2015): 30-35. http://www.scopus.com/inward/record.url?eid=2-s2.0-84962016038&partnerID=MN8TOARS.
    10.14715/cmb/2015.61.1.5
  43. Avolio, E.; Rodriguez-Arabaolaza, I.; Spencer, H.L.; Riu, F.; Mangialardi, G.; Slater, S.C.; Rowlinson, J.; et al. "Expansion and characterization of neonatal cardiac pericytes provides a novel cellular option for tissue engineering in congenital heart disease". Journal of the American Heart Association 4 6 (2015): e002043-e002043. http://www.scopus.com/inward/record.url?eid=2-s2.0-85018199859&partnerID=MN8TOARS.
    10.1161/JAHA.115.002043
  44. Spencer, H.L.; Slater, S.C.; Rowlinson, J.; Morgan, T.; Culliford, L.A.; Guttridge, M.; Emanueli, C.; Angelini, G.; Madeddu, P.. "A journey from basic stem cell discovery to clinical application: The case of adventitial progenitor cells". Regenerative Medicine 10 1 (2015): 39-47. http://www.scopus.com/inward/record.url?eid=2-s2.0-84920722359&partnerID=MN8TOARS.
    10.2217/rme.14.64
  45. Floris, I.; Descamps, B.; Vardeu, A.; Mitic, T.; Posadino, A.M.; Shantikumar, S.; Sala-Newby, G.; et al. "Gestational Diabetes Mellitus Impairs Fetal Endothelial Cell Functions Through a Mechanism Involving MicroRNA-101 and Histone Methyltransferase Enhancer of Zester Homolog-2". Arteriosclerosis, Thrombosis, and Vascular Biology 35 3 (2015): 664-674. http://www.scopus.com/inward/record.url?eid=2-s2.0-84921875766&partnerID=MN8TOARS.
    10.1161/ATVBAHA.114.304730
  46. Angelini, T.G.; Emanueli, C.. "MicroRNAs as clinical biomarkers?". Frontiers in Genetics 6 JUL (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84940103911&partnerID=MN8TOARS.
    10.3389/fgene.2015.00240
  47. Gubernator, M.; Slater, S.C.; Spencer, H.L.; Spiteri, I.; Sottoriva, A.; Riu, F.; Rowlinson, J.; et al. "Epigenetic Profile of Human Adventitial Progenitor Cells Correlates with Therapeutic Outcomes in a Mouse Model of Limb Ischemia". Arteriosclerosis, Thrombosis, and Vascular Biology 35 3 (2015): 675-688. http://www.scopus.com/inward/record.url?eid=2-s2.0-84922215013&partnerID=MN8TOARS.
    10.1161/ATVBAHA.114.304989
  48. Avolio, E.; Meloni, M.; Spencer, H.L.; Riu, F.; Katare, R.; Mangialardi, G.; Oikawa, A.; et al. "Combined intramyocardial delivery of human pericytes and cardiac stem cells additively improves the healing of mouse infarcted hearts through stimulation of vascular and muscular repair". Circulation Research 116 10 (2015): e81-e94. http://www.scopus.com/inward/record.url?eid=2-s2.0-84928601892&partnerID=MN8TOARS.
    10.1161/CIRCRESAHA.115.306146
  49. Smith, T.; Rajakaruna, C.; Caputo, M.; Emanueli, C.. "MicroRNAs in congenital heart disease". Annals of Translational Medicine 3 21 (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-85015490983&partnerID=MN8TOARS.
    10.3978/j.issn.2305-5839.2015.12.25
  50. Dang, Z.; Maselli, D.; Spinetti, G.; Sangalli, E.; Carnelli, F.; Rosa, F.; Seganfreddo, E.; et al. "Sensory neuropathy hampers nociception-mediated bone marrow stem cell release in mice and patients with diabetes". Diabetologia 58 11 (2015): 2653-2662. http://www.scopus.com/inward/record.url?eid=2-s2.0-84942988696&partnerID=MN8TOARS.
    10.1007/s00125-015-3735-0
  51. Caputo, M.; Saif, J.; Rajakaruna, C.; Brooks, M.; Angelini, G.D.; Emanueli, C.. "MicroRNAs in vascular tissue engineering and post-ischemic neovascularization". Advanced Drug Delivery Reviews 88 (2015): 78-91. http://www.scopus.com/inward/record.url?eid=2-s2.0-84937525923&partnerID=MN8TOARS.
    10.1016/j.addr.2015.05.003
  52. Mitic, T.; Caporali, A.; Floris, I.; Meloni, M.; Marchetti, M.; Urrutia, R.; Angelini, G.D.; Emanueli, C.. "EZH2 modulates angiogenesis in vitro and in a mouse model of limb ischemia". Molecular Therapy 23 1 (2015): 32-42. http://www.scopus.com/inward/record.url?eid=2-s2.0-84920696082&partnerID=MN8TOARS.
    10.1038/mt.2014.163
  53. Duggirala, A.; Delogu, F.; Angelini, T.G.; Smith, T.; Caputo, M.; Rajakaruna, C.; Emanueli, C.. "Non coding RNAs in aortic aneurysmal disease". Frontiers in Genetics 6 APR (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84933509543&partnerID=MN8TOARS.
    10.3389/fgene.2015.00125
  54. Caporali, A.; Meloni, M.; Nailor, A.; Mitic, T.; Shantikumar, S.; Riu, F.; Sala-Newby, G.B.; et al. "P75NTR-dependent activation of NF-¿B regulates microRNA-503 transcription and pericyte-endothelial crosstalk in diabetes after limb ischaemia". Nature Communications 6 (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84939130561&partnerID=MN8TOARS.
    10.1038/ncomms9024
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Activities

Committee member

Activity description
Role 		Institution / Organization
2022/01/02 - Current Member of BHF Fellowship Committee - evaluating Fellowship Grant applications for funding by the BHF
Member
 British Heart Foundation, United Kingdom
2018/06/01 - Current American Society of Gene and Cell Therapy - Board Member
Member
 American Society of Gene & Cell Therapy, United States
2017/06/01 - Current Diabetes UK - Member of Scientific Advisory Group (SRAG)
Advisor / Consultant
 Diabetes UK, United Kingdom
2017/06/01 - Current EU Cost Action - Catalysing transcriptomics research in cardiovascular disease
President / Vice-president
 EU-CARDIOPROTECTION COST-Action, Belgium

Evaluation committee

Activity description
Role 		Institution / Organization Funding entity
2015/01/03 - Current Grant Reviewer for the Ministry of Health Singapore
Evaluator
 Government of Singapore, Singapore