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Identification

Personal identification

Full name
Omer Markovitch

Citation names

  • Markovitch, Omer

Author identifiers

Ciência ID
3F1A-E5CC-0F53
ORCID iD
0000-0002-9706-5323
Google Scholar ID
7HATWpEAAAAJ

Email addresses

  • omermar@gmail.com (Professional)

Websites

Knowledge fields

  • Exact Sciences - Physical Sciences - Chemical Physics
  • Exact Sciences - Chemical Sciences
  • Natural sciences - Biological Sciences - Evolutionary Biology
  • Exact Sciences - Chemical Sciences - Organic Chemistry

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese Beginner (A1) Beginner (A1) Beginner (A1) Beginner (A1)
Education
Degree Classification
2014
Concluded
 - (Doktor (PhD))
Weizmann Institute of Science, Israel
"Systems-Chemistry Approach to Prebiotic Evolution" (THESIS/DISSERTATION)
2008
Concluded
 Chemistry (Master)
Hebrew University of Jerusalem, Israel
"Protonated Water" (THESIS/DISSERTATION)
2005
Concluded
 Chemistry (Bachelor)
Hebrew University of Jerusalem, Israel
Affiliation

Science

Category
Host institution 		Employer
2025 - Current Auxiliary Researcher (Research) Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal
2017 - Current Principal Investigator (Research) Blue Marble Space Institute of Science, United States
2021 - 2022 Visiting Researcher (Research) Rijksuniversiteit Groningen Faculteit voor Wiskunde en Natuurwetenschappen, Netherlands
Groningen Institute for Evolutionary Life Sciences, Netherlands
(...)
2017 - 2021 Postdoc (Research) Rijksuniversiteit Groningen Faculteit voor Wiskunde en Natuurwetenschappen, Netherlands
Rijksuniversiteit Groningen Stratingh Institute for Chemistry, Netherlands
(...)
2016 - 2017 Visiting Researcher (Research) Tokyo Institute of Technology , Japan
Earth-Life Science Institute , Japan
2014 - 2016 Postdoc (Research) University of Newcastle upon Tyne, United Kingdom
University of Newcastle upon Tyne, United Kingdom
Outputs

Publications

Book chapter
  1. Eloi Camprubi; Markovitch, Omer; Kamila B. Muchowska; Sijbren Otto; Inge Loes ten Kate. "Prebiotic chemistry: From dust to molecules and beyond". 19-47. Elsevier, 2022.
    Published • 10.1016/b978-0-12-824162-2.00005-1
Conference abstract
  1. Doron Lancet; Raphael Zidovetzki; Shenhav Barak; Markovitch, Omer. "Metabolic GARD: Replicating Catalytic Network of Lipid-Anchored Metabolites". Paper presented in XVIIIth Intl Conf on Origin of Life 2017, 2017.
    Published
Conference paper
  1. Markovitch, Omer; Weizmann Institute of Science; Lancet Doron. "Prebiotic Evolution of Molecular Assemblies: From Molecules to Ecology". 2013.
    Published • 10.7551/978-0-262-31709-2-ch020
Journal article
  1. Eleveld, Marcel J.; Wu, Juntian; Liu, Kai; Ottelé, Jim; Markovitch, Omer; Kiani, Armin; Herold, Lukas C.; et al. "Departure from randomness: Evolution of self-replicators that can self-sort through steric zipper formation". Chem (2024): 102374. https://doi.org/10.1016/j.chempr.2024.11.012.
    10.1016/j.chempr.2024.11.012
  2. Markovitch, Omer; Wu, Juntian; Otto, Sijbren. Corresponding author: Markovitch, Omer. "Binding of Precursors to Replicator Assemblies Can Improve Replication Fidelity and Mediate Error Correction [Hot Paper]". Angewandte Chemie International Edition (2024): e202317997. http://dx.doi.org/10.1002/anie.202317997.
    Open access • 10.1002/anie.202317997
  3. Mayer, Christian; Lancet, Doron; Markovitch, Omer. "The GARD Prebiotic Reproduction Model Described in Order and Complexity". Life 14 3 (2024): 288. https://doi.org/10.3390/life14030288.
    10.3390/life14030288
  4. Bin Liu; Juntian Wu; Marc Geerts; Markovitch, Omer; Charalampos G. Pappas; Kai Liu; Sijbren Otto. "Out-of-Equilibrium Self-Replication Allows Selection for Dynamic Kinetic Stability in a System of Competing Replicators". Angewandte Chemie International Edition (2022): https://doi.org/10.1002/anie.202117605.
    Open access • Published • 10.1002/anie.202117605
  5. Shuo Yang; Gael Schaeffer; Elio Mattia; Markovitch, Omer; Kai Liu; Andreas S. Hussain; Jim Ottelé; Ankush Sood; Sijbren Otto. "Chemical Fueling Enables Molecular Complexification of Self-Replicators**". Angewandte Chemie International Edition 60 20 (2021): 11344-11349. http://dx.doi.org/10.1002/anie.202016196.
    Published • 10.26434/chemrxiv.12162135
  6. Markovitch, Omer; Jim Ottelé; Obe Veldman; Sijbren Otto. Corresponding author: Markovitch, Omer. "Automated device for continuous stirring while sampling in liquid chromatography systems". Communications Chemistry 3 (2020): 180. https://doi.org/10.1038/s42004-020-00427-5.
    Open access • Published • 10.1038/s42004-020-00427-5
  7. Gregory B. Boursalian; Eise R. Nijboer; Ruth Dorel; Lukas Pfeifer; Markovitch, Omer; Alex Blokhuis; Ben L. Feringa. Corresponding author: Ben L. Feringa. "All-Photochemical Rotation of Molecular Motors with a Phosphorus Stereoelement". Journal of the American Chemical Society 142 39 (2020): 16868-16876. https://doi.org/10.1021/jacs.0c08249.
    Open access • Published • 10.1021/jacs.0c08249
  8. Rafael Loureiro; Markovitch, Omer; Crystal S Riley; H James Cleaves, II; I Haritina Mogo¿anu; Ivan G Paulino-Lima; Jeffrey J Marlow; Sanjoy M Som. Corresponding author: Markovitch, Omer. "Perspective: Science policy through public engagement". Science and Public Policy (2020): https://doi.org/10.1093/scipol/scaa039.
    Open access • Published • 10.1093/scipol/scaa039
  9. Sourav Maity; Jim Ottelé; Guillermo Monreal Santiago; Pim W. J. M. Frederix; Peter Kroon; Markovitch, Omer; Marc C. A. Stuart; et al. "Caught in the Act: Mechanistic Insight into Supramolecular Polymerization-Driven Self-Replication from Real-Time Visualization". Journal of the American Chemical Society 142 32 (2020): 13709-13717. https://doi.org/10.1021/jacs.0c02635.
    Open access • Published • 10.1021/jacs.0c02635
  10. Markovitch, Omer; Boris H. Kramer; Franz J. Weissing; G. Sander van Doorn; Sijbren Otto. Corresponding author: Markovitch, Omer. "Competition Dynamics in a Chemical System of Self-replicating Macrocycles". Artificial Life (2020): http://dx.doi.org/10.1162/isal_a_00289.
    Open access • Published • 10.1162/isal_a_00289
  11. Doron Lancet; Raphael Zidovetzki; Markovitch, Omer. "Systems protobiology: origin of life in lipid catalytic networks". Journal of The Royal Society Interface 15 144 (2018): 20180159-20180159. https://doi.org/10.1098/rsif.2018.0159.
    Open access • Published • 10.1098/rsif.2018.0159
  12. Markovitch, Omer; Natalio Krasnogor. "Predicting species emergence in simulated complex pre-biotic networks". PLOS ONE 13 2 (2018): e0192871-e0192871. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0192871.
    Open access • Published • 10.1371/journal.pone.0192871
  13. Fellermann, H.; Markovitch, Omer; Gilfellon, O.; Madsen, C.; Phillips, A.. "Toward Programmable Biology". ACS Synthetic Biology 5 8 (2016): 793-794. https://pubs.acs.org/doi/10.1021/acssynbio.6b00213.
    Open access • Published • 10.1021/acssynbio.6b00213
  14. Markovitch, Omer; Doron Lancet. "Multispecies population dynamics of prebiotic compositional assemblies". Journal of Theoretical Biology 357 (2014): 26-34. https://www.sciencedirect.com/science/article/abs/pii/S0022519314002756.
    Open access • Published • 10.1016/j.jtbi.2014.05.005
  15. Renan Gross; Itzhak Fouxon; Doron Lancet; Markovitch, Omer. Corresponding author: Markovitch, Omer. "Quasispecies in population of compositional assemblies". BMC Evolutionary Biology 14 1 (2014): 265-265. http://dx.doi.org/10.1186/s12862-014-0265-1.
    Open access • Published • 10.1186/s12862-014-0265-1
  16. Markovitch, Omer; Daniel Sorek; Leong Ting Lui; Doron Lancet; Natalio Krasnogor. Corresponding author: Markovitch, Omer. "Is There an Optimal Level of Open-Endedness in Prebiotic Evolution?". Origins of Life and Evolution of Biospheres 42 5 (2012): 469-474. http://dx.doi.org/10.1007/s11084-012-9309-y.
    Published • 10.1007/s11084-012-9309-y
  17. Markovitch, Omer; Lancet, D.. "Excess mutual catalysis is required for effective evolvability". Artificial Life 18 3 (2012): 243-266. https://direct.mit.edu/artl/article/18/3/243/2728/Excess-Mutual-Catalysis-Is-Required-for-Effective.
    Open access • Published • 10.1162/artl-a-00064
  18. Don L Armstrong; Markovitch, Omer; Raphael Zidovetzki; Doron Lancet. "Replication of simulated prebiotic amphiphile vesicles controlled by experimental lipid physicochemical properties". Physical Biology 8 6 (2011): 066001-066001. http://dx.doi.org/10.1088/1478-3975/8/6/066001.
    Published • 10.1088/1478-3975/8/6/066001
  19. Ran Kafri; Markovitch, Omer; Doron Lancet. "Spontaneous chiral symmetry breaking in early molecular networks". Biology Direct 5 1 (2010): http://dx.doi.org/10.1186/1745-6150-5-38.
    Open access • Published • 10.1186/1745-6150-5-38
  20. Markovitch, Omer; Inger, A.; Shenhav, B.; Lancet, D.. "Replication and darwinian selection define life's origin". Origins of Life and Evolution of Biospheres 40 4 (2010): 484-488. http://www.scopus.com/inward/record.url?eid=2-s2.0-77954911470&partnerID=MN8TOARS.
  21. Markovitch, Omer; Noam Agmon. "Reversible geminate recombination of hydrogen-bonded water molecule pair". The Journal of Chemical Physics 129 8 (2008): 084505-084505. http://dx.doi.org/10.1063/1.2968608.
    Published • 10.1063/1.2968608
  22. Markovitch, Omer; Hanning Chen; Sergei Izvekov; Francesco Paesani; Gregory A. Voth; Noam Agmon. "Special Pair Dance and Partner Selection: Elementary Steps in Proton Transport in Liquid Water". The Journal of Physical Chemistry B 112 31 (2008): 9456-9466. http://dx.doi.org/10.1021/jp804018y.
    Published • 10.1021/jp804018y
  23. Markovitch, Omer; Noam Agmon. "The distribution of acceptor and donor hydrogen-bonds in bulk liquid water". Molecular Physics 106 2-4 (2008): 485-495. http://dx.doi.org/10.1080/00268970701877921.
    Published • 10.1080/00268970701877921
  24. Markovitch, Omer; Noam Agmon. "Structure and Energetics of the Hydronium Hydration Shells". The Journal of Physical Chemistry A 111 12 (2007): 2253-2256. http://dx.doi.org/10.1021/jp068960g.
    Published • 10.1021/jp068960g
Magazine article
  1. Markovitch, Omer. Corresponding author: Markovitch, Omer. "How everything began", Galileo, 2012, https://microbiology-heb.blogspot.com/2012/12/How-Life-Start.html.
Preprint
  1. Liu, Kai; Markovitch, Omer; van Ewijk, Chris; Knelissen, Yari Katar; Kiani, Armin; Eleveld, Marcel; Roos, Wouter H.; Otto, Sijbren. "Selection for Photocatalytic Function through Darwinian Evolution of Synthetic Self-Replicators". 2024. https://doi.org/10.26434/chemrxiv-2024-x4fdr-v2.
    10.26434/chemrxiv-2024-x4fdr-v2
  2. OOLEN writing team. "What it takes to solve the Origin(s) of Life: An integrated review of techniques". 2023. https://arxiv.org/abs/2308.11665.
  3. Markovitch, Omer; Olaf Witkowski; Nathaniel Virgo. Corresponding author: Markovitch, Omer. "Chemical Heredity as Group Selection at the Molecular Level". 2018. https://arxiv.org/abs/1802.08024.
    https://doi.org/10.48550/arXiv.1802.08024
Thesis / Dissertation
  1. "Systems-chemistry approach to prebiotic evolution". PhD, 2014. https://doi.org/10.5281/zenodo.1134791.
    https://doi.org/10.5281/zenodo.1134791
  2. "Protonated Water". Master, Hebrew University of Jerusalem, 2007. https://huji.primo.exlibrisgroup.com/discovery/fulldisplay?vid=972HUJI_INST:972HUJI_V1&tab=LibraryCatalog&docid=alma990014428490203701&context=L&search_scope=MyInstitution&lang=en.

Other

Dataset
  1. Omer Markovitch; Olaf Witkowski; Nathaniel Virgo. Accompnaying Dataset For: Chemical Heredity As Group Selection At The Molecular Level.
    10.5281/ZENODO.1172466
  2. Omer Markovitch; Natalio Krasnogor. Accompanying Dataset For: Predicting Species Emergence In Simulated Complex Pre-Biotic Networks.
    10.5281/ZENODO.56534
  3. Omer Markovitch; Jim Ottelé; Sijbren Otto. Accompanying files: Automated device for continuous stirring while sampling in liquid chromatography systems.
    10.5281/ZENODO.3898290
  4. Markovitch, Omer; Wu, Juntian; Otto, Sijbren. Accompanying dataset: Binding of precursors to replicator assemblies can improve replication fidelity and mediate error correction. 2023.
    10.5281/zenodo.8287184
Other output
  1. BCAM hosted a workshop on “Theoretical and Experimental Approaches to Goal-Directed Behavior”. 2024. Press Release. https://www.bcamath.org/en/news-events/news/bcam-hosted-workshop-theoretical-and-experimental-approaches-goal-directed.
  2. For the first time, large self-replicating molecules win evolution. 2021. Shuo Yang; Markovitch, Omer. https://sciworthy.com/for-the-first-time-self-replicating-molecules-win-evolution/.
  3. Using 3D printing to automate experiments involving stirring and liquid chromatography. 2020. Markovitch, Omer; Jim Ottelé. https://chemistrycommunity.nature.com/posts/using-3d-printing-to-automate-experiments-involving-stirring-and-liquid-chromatography.
  4. How did life get started? [YouTube]. Self-replicating systems are likely to have played a central role in the origin of life. The goal of the project is to learn principles related to the emergent behaviour we call ‘life’, from different classes of self-replicating systems including synthetic chemical replicators, RNA viruses and bacteria. This will be achieved by investigating the diversification and adaptive potential of each syste. 2019. Markovitch, Omer. https://www.youtube.com/watch?v=puJVWPWnUvg.
  5. Wikipedia ‘Hackathon’. 2017. Markovitch, Omer. https://bmsis.org/outreach-wikipedia-hackathon/.
  6. Commentary: Excess mutual catalysis is required for effective evolvability. The essays listed below (with links to pdfs) were originally published online as part of the Origin of Life Focus Group within the NASA Astrobiology Institute. 2012. Markovitch, Omer. https://www.nasa.gov/ames/spacescience-and-astrobiology/center-for-the-emergence-of-life/essays-on-the-emergence-of-life.
Software
  1. Markovitch, Omer. "Chemical model to simulate all the oxidation and exchange reactions of dithiol building blocks". 2024.
    10.5281/zenodo.12686958