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Sandra Simões is a Principal Investigator at the Department of Pharmacy, Pharmacology and Health Technologies and at Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa. She is member of the Animal Welfare Body of the Faculty of Pharmacy, University of Lisbon. Both advanced technologies for drug delivery and pre-clinical assays have motivated her research, which has been focused on design, development and biological evaluation of optimal drug delivery systems for dermal and transdermal delivery, for small and large molecules, with special emphasis on phospholipid-based nanocarriers. Research activity deals with drug-excipient and drug-skin interactions, and development of animal models of acute and chronic inflammation, skin infection and wound-healing. These studies require optimization of techniques for the in vitro, ex vivo and in vivo assessment of dermal and transdermal drug delivery. In the last years Sandra Simões has been working on the valorisation of food processing industry by-products and the application of extracted bioactives in skin health. More recently she has been involved in the establishment and optimization of mice models of breast cancer brain metastasis and glioblastoma for the evaluation of therapeutic efficacy of new drug candidates.
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Identification

Personal identification

Full name
Sandra Simões

Citation names

  • Simões, Sandra

Author identifiers

Ciência ID
4011-196E-E4EA
ORCID iD
0000-0002-5685-1790
Researcher Id
C-2614-2014
Scopus Author Id
8724939200

Languages

Language Speaking Reading Writing Listening Peer-review
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
French Beginner (A1) Intermediate (B1) Beginner (A1) Beginner (A1)
Spanish; Castilian Intermediate (B1) Intermediate (B1) Beginner (A1) Intermediate (B1)
Education
Degree Classification
2022
Concluded
 Tecnologia Farmacêutica (Título de Agregado)
Universidade de Lisboa Faculdade de Farmácia, Portugal
 Approved
2005
Concluded
 Farmácia (Doutoramento)
Major in Tecnologia Farmacêutica
Universidade de Lisboa Faculdade de Farmácia, Portugal
"Transdermal delivery of therapeutic enzymes" (THESIS/DISSERTATION)
 Summa cum laude
1994
Concluded
 Ciências Farmacêuticas (Licenciatura)
Universidade de Lisboa Faculdade de Farmácia, Portugal
 16 valores
Affiliation

Science

Category
Host institution 		Employer
2023/11/13 - Current Principal Investigator (Research) Universidade de Lisboa Faculdade de Farmácia, Portugal
2007/04/01 - Current Principal Investigator (Research) Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
2009/01/01 - 2023/11/12 Auxiliary Researcher (Research) Universidade de Lisboa Faculdade de Farmácia, Portugal
2004/12/13 - 2008/12/31 Auxiliary Researcher (Research) Instituto Nacional de Engenharia Tecnologia e Inovação, Portugal
2001/05/09 - 2004/12/12 Research Assistant (Research) Instituto Nacional de Engenharia Tecnologia e Inovação, Portugal
1999/06/30 - 2001/05/08 Research Trainee (Research) Instituto Nacional de Engenharia Tecnologia e Inovação, Portugal
1994/12/15 - 1995/09/30 Researcher (Research) Instituto Nacional de Engenharia Tecnologia e Inovação, Portugal
1994/06/01 - 1994/10/31 Researcher (Research) Forbitec, Portugal
INETI - Instituto de Investigação, Tecnologia e Inovação, Portugal

Others

Category
Host institution 		Employer
2016/05/30 - Current Membro do ORBEA-FFULisboa Universidade de Lisboa Faculdade de Farmácia, Portugal
Universidade de Lisboa Faculdade de Farmácia, Portugal
1995/10/01 - 1998/05/31 PRAXIS XXI PhD grantee Fundação para a Ciência e a Tecnologia, Portugal
INETI - Instituto de Investigação, Tecnologia e Inovação, Portugal
Projects

Contract

Designation Funders
2022/03/01 - Current A novel tolerogenic liposome allergen immunotherapy for dogs in the horizon
EXPL/CVT-CVT/1458/2021
Researcher
2017/04 - Current VIH_TRANFERSOME: Inibidor de fusão veiculado em Transfersomas para libertação transdérmica
PGG/006/2016
Researcher
Programa Gilead Génese
2018/10/01 - 2021/10/01 HOTsPOT - Novel upconversion nanoparticles for multimodal therapy of melanoma: pHOtothermal Therapy, PhOtodynamic therapy and chemoTherapy.
hotspot
Researcher
Ongoing
2018/10/01 - 2021/09/30 MultiTarget - Multitarget drug discovery for malaria: a strategy to target all stages of the Plasmodium life-cycle
Researcher
2018/10/01 - 2021/09/30 Ser4Skin - Serotonergic-based therapies to decrease the impact of moderate to severe psoriasis: translation of fundamental research into industry.
Ser4Skin
Researcher
Fundação para a Ciência e a Tecnologia
Ongoing
2018/06/01 - 2021/05/31 3SLYCO - Sustainable, Safe, and Scalable (3S) approach for lycopene valorization: driving the knowledge toward an academia-industry interface for topical treatment of inflammation.
info:eu-repo/grantAgreement/FCT/SFRH/SFRH2%FBD2%F82932%F2002/PT
Principal investigator
Fundação para a Ciência e a Tecnologia
Ongoing
2019/10/01 - 2020/09/30 Smart3D-TDDS - Ion jelly-Sensing Smart 3D Patch for transdermal drug delivery
Smart3D-TDDS
Researcher
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
 Universidade de Lisboa Instituto de Investigação do Medicamento
Ongoing
2017/01 - 2019/12 PRECISION ONCOLOGY BY INNOVATIVE THERAPIES AND TECHNOLOGIES
SAICTPAC/0019/2015
 Fundação para a Ciência e a Tecnologia
2018/10/01 - 2019/09/30 NanoBaR - Development of an advanced topical insulin formulation for skin burn regeneration: an experimental approach from fundamental to translational research.
Researcher
Universidade de Lisboa Instituto de Investigação do Medicamento
2018/09/01 - 2019/09/30 Targeted liposomal antioxidant and anti-inflammatory therapy for liver ischemic reperfusion injury.
Researcher
Ongoing
2018 - 2019 GelEver - Gel oral mucoadesivo de Fosfato de Dexametasona como estratégica profiláctica para a mucosite por everolímus
Researcher
Ongoing
2016/10/01 - 2017/09/30 EXO-UCX - The use of exosomes derived from umbilical cord tissue mesenchymal stromal cells (UCX®) for improving regeneration of open cutaneous wounds.
Researcher
Universidade de Lisboa Instituto de Investigação do Medicamento
Concluded
2016 - 2016 LIGHT WATER - Effects of water depleted from heavy isotopes of oxygen and hydrogen (light water) on physical properties and penetration of plant-derived polyphenols through cutaneous barrier
Researcher
Medena
2015 - 2016 Uma Viagem no Reino da Pele
Apoio a Actividades dos Docentes, Investigadores e Restantes Trabalhadores da ULisboa 2014
Researcher
Universidade de Lisboa
2015 - 2016 Arroz+
QREN I&DT Co-Promoção nº38749, Novarroz, Produtos Alimentares SA/ISA/FFUL
 QREN
2013/04 - 2015/12 Fighting TB: Development of microparticulate systems to target alveolar macrophages in tuberculosis therapy
Provided by PTCRIS: 124096
Researcher
Fundação para a Ciência e a Tecnologia
2014/03 - 2015/09 PRIMED-UCX - Priming of Mesenchymal Stromal Cells from the Umbilical Cord Tissue (UCX®) as a Means of Incrementing Their Therapeutic Potency for Rheumatoid Arthritis
Provided by PTCRIS: 133330
Principal investigator
Fundação para a Ciência e a Tecnologia
2013/07 - 2014/12 LEISHTOPIDEA - Cutaneous leishmaniasis: an innovative idea to explore the topical treatment of skin lesions
Provided by PTCRIS: 127814
Researcher
Fundação para a Ciência e a Tecnologia
2010/04 - 2013/09 Lung CYD-DDS (cyclodextrin-based drug delivery systems) for inhalation
Provided by PTCRIS: 98733
Researcher
Fundação para a Ciência e a Tecnologia
2008 - 2011 ONCOTERA - Descoberta de compostos para terapia do cancro do colon
QREN 2008/1433
 QREN
2007 - 2008 Desenvolvimento de novos fármacos para doenças inflamatórias da pele
Principal investigator
INETI - Instituto de Investigação, Tecnologia e Inovação, Portugal

Alfama, Portugal
2004 - 2006 Xilo-oligossacáridos purificados como agentes anti-ulcerosos
XILOGASTRO/AdI/2003
Researcher
Agência de Inovação
2000 - 2004 Transporte Transdérmico de Proteínas com Actividade Terapêutica
POCTI/1999/FCB/35787
Researcher
Fundação para a Ciência e a Tecnologia
2002 - 2003 Development of xylo-oligosaccharides and xylitol for use in pharmaceutical and food industries-FAIR
FAIR-PI97 3811
Researcher
Agência de Inovação
1997 - 1999 Desenvolvimento de Vectores para Administração Dérmica e Transdérmica de Proteínas com Actividade Terapêutica
PRAXIS XXI, P/SAU/SAU96/96
Researcher
Fundação para a Ciência e a Tecnologia
1992 - 1994 Bioconjugados e Vectores para Fins Terapêuticos
PBIC/SAU/1551/92
Researcher
Fundação para a Ciência e a Tecnologia
Outputs

Publications

Book
  1. Simões, Sandra. Carrier-Mediated Dermal Delivery: Applications in the Prevention and Treatment of Skin Disorders. 2017.
Book chapter
  1. Martins AM, ; Ascenso A; Costa A ; Simões, Sandra; Ribeiro HM; Joana Marto. "Topical Dosage Forms: Bioequivalence at a Glance". In Time-proof perspectives on bioquivalence. New York: Nova Science Publishers, 2023.
  2. Faria-Silva, Ana Catarina; Mota, Ana Luísa; Costa, Ana Margarida; Silva, Ana Margarida; Ascenso, Andreia; Reis, Catarina; Marto, Joana; et al. "Application of natural raw materials for development of cosmetics through nanotechnology". In Nanotechnology for the Preparation of Cosmetics Using Plant-Based Extracts, 157-201. Elsevier, 2022.
    10.1016/b978-0-12-822967-5.00014-x
  3. Simões, S.; Costa, A.; Faria-Silva, A.C.; Ascenso, A.; Marto, J.; Carvalheiro, M.; Gonçalves, L.M.; et al. "Sustainable valorization of food-processing industry by-products: challenges and opportunities to obtain bioactive compounds". In Valorization of Agri-Food Wastes and By-Products, 619-644. Elsevier, 2021.
    10.1016/b978-0-12-824044-1.00023-4
  4. "Colloidal Disperse Systems: Microemulsions and Nanoemulsions". 2021.
    10.1007/978-3-030-63389-9
  5. Faria-Silva, Ana Catarina; Costa, Ana Margarida; Ascenso, Andreia; Ribeiro, Helena Margarida; Marto, Joana; Gonçalves, Lídia Maria; Carvalheiro, Manuela; Simões, Sandra. "Nanoemulsions for cosmetic products". In Nanocosmetics, 59-77. Elsevier, 2020.
    10.1016/b978-0-12-822286-7.00004-8
  6. "Lipid Vesicles for Skin Delivery: Evolution from first generation". Singapore, 2017.
    Published
  7. "Lipid-based nanocarriers for the treatment of infected skin lesions". Singapore, 2017.
    Published
  8. "Microemulsões e nanoemulsões". Portugal, 2012.
    Published
  9. "Formulation of NPDDS for Macromolecules". In Drug Delivery Nanoparticles: Formulation and Characterization. United States, 2009.
  10. "Enzimas na Indústria de Cosméticos". Brazil, 2008.
    Published
Conference abstract
  1. Marta Pinto; Solange Gil; Simões, Sandra; Gonçalves, Lídia; Ramio Lluch, Laura; Bizarro, Ana; Beatriz Fernandes; Ana Mafalda Lourenço. "Shaping the future of canine atopic dermatitis: a novel tolerogenic nanoparticle based topical allergen immunotherapy".". Porto, 2023.
  2. Camões, Sérgio P.; Dias, Catarina T.; Rodrigues, Joana S; Serras, Ana S.; Gaspar, Maria Manuela; Simões, Sandra; Ferreira, R.; et al. "Delivery of exosomes derived from 3D-cultured human neonatal mesenchymal stromal cells improves cutaneous wound healing". Paper presented in 11th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies, 2019.
    10.3389/978-2-88945-675-8
Conference poster
  1. Faria-Silva, Catarina; Poças, Marta; Cunha, Daniela; Marto, Joana; Simões, Pedro; Carvalheiro, Manuela; Simões, Sandra. "Green Tomato Extract mediated biosynthesis of Silver Nanoparticles. Biosynthesis, characterization and biological properties". Paper presented in XV Spanish-Portuguese Conference on Controlled Drug Delivery, 2024.
  2. Faria-Silva, Catarina; Scavone, Denise; Marto, Joana; Simões, Pedro; Carvalheiro, Manuela; Simões, Sandra. "Development of an alpha-tomatine foam for cutaneous application: a sustainable approach for saponins use". Paper presented in XV Spanish-Portuguese Conference on Controlled Drug Delivery, 2024.
  3. Faria-Silva, Catarina; Scavone, Denise; Marto, Joana; Simões, Pedro; Carvalheiro, Manuela; Simões, Sandra. "Alpha-tomatine: a promising natural ingredient for skin care formulations". Paper presented in Skin and Formulation, 6th Symposium, 2023.
  4. Faria-Silva, Catarina; Scavone, Denise; Santos, Maria Soledade; Simões, Pedro; Carvalheiro, Manuela; Simões, Sandra. "Characterization of surfactants present in a tomatine-containing extract". Paper presented in 14th iMed.ULisboa Postgraduate Students Meeting, 2023.
  5. Faria-Silva, Catarina; Scavone, Denise; Santos, Maria Soledade; Simões, Pedro; Carvalheiro, Manuela; Simões, Sandra. "Characterization of a natural extract derived from green tomato". Paper presented in 15º Encontro Nacional de Química Física, 2023.
  6. Faria-Silva, Catarina; Scavone, Denise; Simões, Pedro; Carvalheiro, Manuela; Simões, Sandra. "Green tomato-derived foam: simultaneous use of plant glycoalkaloids as excipients and as active substances". Paper presented in IV Young Scientist Meeting of the Spanish Portuguese Local Chapter - Controlled Release Society (SPC-CRS), 2023.
  7. Cunha, Daniela; Faria-Silva, Catarina; Marto, Joana; Simões, Pedro; Carvalheiro, Manuela; Simões, Sandra. "Silver nanoparticles synthesis using Green Tomatoes Extract: Preliminary studies". Paper presented in IV Young Scientist Meeting of the Spanish Portuguese Local Chapter - Controlled Release Society (SPC-CRS), 2023.
  8. Faria-Silva, Catarina; Simões, Pedro; Carvalheiro, Manuela; Simões, Sandra. "Tomatine extracted from green tomatoes: the beginning of a new topical anti leishmanial treatment?". Paper presented in 1st Egas Moniz One Health Simposium, 2022.
  9. Faria-Silva, AC; Eleutério, Carla Vânia; Simões, Pedro; Carvalheiro, Manuela; Simões, Sandra. "Valorization of natural glycoalkaloids from tomato: an optimized HPLC method for the quantification of tomatine". Paper presented in 13th iMed.ULisboa Postgraduate Students Meeting, 2022.
  10. Ferreira-Silva, Margarida; Faria-Silva, C.; Carvalheiro, Manuela; Simões, Sandra; Fernandes, Eduarda; Baptista, Pedro; Alexandra R Fernandes; Corvo, M. Luisa. "Quercetin liposomes for hepatic ischemia and reperfusion injury a promising therapeutic approach". Paper presented in First Symposium on Advanced Technologies on Drug Delivery, 2021.
  11. Camões, Sérgio P.; Bulut, Ozlem; Yazar, Volkan; Gaspar, Maria Manuela; Simões, Sandra; Ferreira, R; Vitorino, R; et al. "Exosomes from 3D-cultured MSCs are immunomodulatory and reveal healing proteins sustaining the promotion of cutaneous wound resolution". Paper presented in iMed.ULisboa meeting 2021, 2021.
  12. Pivetta, Thais P.; Simões, Sandra; Ribeiro, Paulo A.; Raposo, Maria. "Complex Liposomes for Phototherapy: development and optimization". Paper presented in NanoPortugal (NPTO2020) Online Conference, 2020.
  13. Ferreira-Silva, Margarida; Faria-Silva, Catarina; Carvalheiro, Manuela Colla; Simões, Sandra; Fernandes, Eduarda; Baptista, Pedro Viana; Fernandes, Alexandra; Corvo, M. Luísa. "Evaluation of anti-inflammatory effect of quercetin liposomes in hepatic ischemia and reperfusion injury". Paper presented in XIII Spanish-Portuguese Conference on Controlled Drug Delivery, 2020.
  14. Carvalheiro, Manuela Colla; Varrica, Carla G.; Faria-Silva, Catarina; Sandri, Giuseppina; Simões, Sandra. "Alopurinol-loaded Nanostructured Lipid Carriers for Topical Application: in vitro and in vivo evaluation.". Paper presented in XIII Spanish-Portuguese Conference on Controlled Drug Delivery, 2020.
  15. Camões, Sérgio P; Gaspar, Maria Manuela; Rodrigues, Joana S; Carvalheiro, M; Simões, Sandra; Santos, Jorge M; Miranda, Joana P G. "Using the secretome of 3D-cultured mesenchymal stromal cells from the umbilical cord tissue for the treatment of rheumatoid arthritis". Paper presented in 11th International Meeting of the Portuguese Society for Stem Cells and Cell Therapy, 2019.
  16. Camões, Sérgio P; Rodrigues, Joana S; Gaspar, Maria Manuela; Simões, Sandra; Ferreira, R.; Barros, A.; Vitorino, R.; Santos, Jorge M.; Miranda, Joana P. "Exploiting the exosomes from 3D cultures of human neonatal mesenchymal stem cells for the treatment of cutaneous wounds". Paper presented in EUROTOX 2019 - 55th Congress of the European Societies of Toxicology, 2019.
    10.1016/j.toxlet.2019.09.002
  17. Camões, Sérgio P.; Rodrigues, Joana S; Gaspar, Maria Manuela; Simões, Sandra; Ferreira, R.; Barros, A.; Vitorino, R.; Santos, Jorge M.; Miranda, Joana P. G.. "The role of exosomes from human MSC 3D cultures in wound healing". Paper presented in EUROTOX 2019 – 55th Congress of the European Societies of Toxicology, 2019.
  18. Vieira, Jennifer; Faria-Silva, Catarina; Eleutério, Carla V.; Marto, Joana; Simões, Sandra; Carvalheiro, Manuela Colla. "Soybean phosphatidylcholine containing deformable vesicles as topical formulations for Amphotericin B.". Paper presented in 6th International Symposium on Phospholipids in Pharmaceutical Research, 2019.
  19. Camões, Sérgio P; Gaspar, Maria Manuela; Rodrigues, Joana S; Carvalheiro, M; Simões, Sandra; Santos, Jorge M; Miranda, Joana P G. "The use of 3D-cultured MSCs’ secretome for rheumatoid arthritis treatment". Paper presented in 11th iMed.ULisboa Postgraduate Students Meeting & 4th i3DU Meeting, 2019.
  20. Faria-Silva, Catarina; Ferreira-Silva, Margarida; Carvalheiro, Manuela Colla; Simões, Sandra; Fernandes, Alexandra R.; Corvo, M. Luísa. "Development of Indomethacin Liposomal Formulations for Hepatic Ischemia/Reperfusion Injury Prevention.". Paper presented in 2019 Controlled Release Society Annual Meeting & Exposition., 2019.
  21. Simões, Sandra; Pivetta, Thais ; Carvalho, Tânia G.; Marcato, Priscyla D.. "Thymol Nanostructured Lipid Carriers for Psoriasis Topical Therapy". Paper presented in XII Spanish-Portuguese Conference on Controlled Drug Delivery, 2018.
  22. Gaspar, MM; Nave, M; Simões, Sandra; Almeida, AJ; Alves, AB; Grenha, Ana. ". Improved therapeutic effect of rifabutin/isoniazid microparticles for the treatment of tuberculosis following pulmonary administration". Paper presented in 21st International Symposium on Microencapsulation, 2017.
  23. Carvalheiro, Manuela; F. Silva, A. Catarina; Esteves, Alexandra M; Eleutério, Carla V.; Cruz, M. Eugénia; Gaspar, M. Manuela; Simões, Sandra. "Lipid-based delivery systems for dinitroanilines in treatment of L. major skin lesions.". Paper presented in 6th World Congress on Leishmaniasis, 2017.
  24. Carvalheiro, Manuela; F. Silva, A. Catarina; Costa, A. Margarida; Esteves Alexandra; Eleutério, Carla V.; Gaspar, M. Manuela; Simões, Sandra. "Ethosomes containing TFL-A for topical treatment of L. major skin lesions". Paper presented in COST Action 1307. Chemotherapy toward diseases caused by endoparasites., 2016.
Journal article
  1. Cunha, Daniela; Faria-Silva, Catarina; Carvalho, Filomena A.; Ascensão, Lia; Simões, Pedro; Carvalheiro, Manuela; Simões, Sandra. "In Vitro, Ex Vivo, and In Vivo Evaluation of Silver Nanoparticles Synthesized Using Green Tomato Extract: Perspectives on Topical Application". Applied Sciences 14 16 (2024): 7309. http://dx.doi.org/10.3390/app14167309.
    10.3390/app14167309
  2. Faria-Silva, Catarina; Eleutério, Carla V.; Simões, Pedro; Carvalheiro, Manuela; Simões, Sandra. "A new method for quantification of tomatine-enriched extracts". Journal of the Science of Food and Agriculture (2024): http://dx.doi.org/10.1002/jsfa.13683.
    10.1002/jsfa.13683
  3. Mota, Joana; Faria-Silva, Catarina; Resendes, Ana; Santos, Maria Isabel; Carvalheiro, Manuela Colla; Lima, Ana; Simões, Sandra. "Silymarin inhibits dermal gelatinolytic activity and reduces cutaneous inflammation". Natural Product Research (2024): 1-12. http://dx.doi.org/10.1080/14786419.2024.2347452.
    10.1080/14786419.2024.2347452
  4. Marto, Joana; Simões, Sandra. "New Horizons in Dermal and Transdermal Drug Delivery Systems". Pharmaceuticals 16 12 (2023): 1654. http://dx.doi.org/10.3390/ph16121654.
    10.3390/ph16121654
  5. Joana Pereira; Daniela Vaz; Inês Figueira; Joana Aniceto-Romão; Istvan Krizbai; Rui Malhó; Joao Rocha; et al. "Breast Cancer Brain Metastases: Implementation and Characterization of a Mouse Model Relying on Malignant Cells Inoculation in the Carotid Artery". Cells 12 16 (2023): 2076-2076. http://dx.doi.org/10.3390/cells12162076.
    10.3390/cells12162076
  6. Gustavo da Silva; André F. S. Luz; Denise Duarte; Diana Fontinha; Vera L. M. Silva; Filipe A. Almeida Paz; Ana M. Madureira; et al. "Facile Access to Structurally Diverse Antimalarial Indoles Using a One-Pot A3 Coupling and Domino Cyclization Approach". ChemMedChem (2023): http://dx.doi.org/10.1002/cmdc.202300264.
    10.1002/cmdc.202300264
  7. Carvalheiro, Manuela C; Simões, Sandra; Faria-Silva, Ana Catarina; Simões P; Bellofatto M; Mota J. "Eco-extracted a-Tomatine as an Antioxidant for Natural Soap". Cosmetics & Toiletries 138 6 (2023): 43-48.
  8. Pedro Francisco; Mariana Neves Amaral; Afonso Neves; Tânia Ferreira-Gonçalves; Ana S. Viana; José Catarino; Pedro Faísca; et al. "Pluronic® F127 Hydrogel Containing Silver Nanoparticles in Skin Burn Regeneration: An Experimental Approach from Fundamental to Translational Research". Gels 9 3 (2023): 200-200. http://dx.doi.org/10.3390/gels9030200.
    10.3390/gels9030200
  9. Inês Vilela de Sousa; Miguel J S Ferreira; Luís B Bebiano; Sandra Simões; Ana Filipa Matos; Rúben F Pereira; Pedro L Granja. "Skin models of cutaneous toxicity, transdermal transport and wound repair". Burns & Trauma 11 (2023): http://dx.doi.org/10.1093/burnst/tkad014.
    10.1093/burnst/tkad014
  10. Thais P. Pivetta; Quirina Ferreira; Tânia Vieira; Jorge C. Silva; Sandra Simões; Paulo A. Ribeiro; Maria Raposo. "Liposomes encapsulating methylene blue and acridine orange: An approach for phototherapy of skin cancer". Colloids and Surfaces B: Biointerfaces 220 (2022): 112901-112901. http://dx.doi.org/10.1016/j.colsurfb.2022.112901.
    10.1016/j.colsurfb.2022.112901
  11. Faria-Silva, Catarina; de Sousa, Miriam; Carvalheiro, Manuela Colla; Simões, Pedro; Simões, Sandra. "Alpha-tomatine and the two sides of the same coin: An anti-nutritional glycoalkaloid with potential in human health". Food Chemistry 391 (2022): 133261. http://dx.doi.org/10.1016/j.foodchem.2022.133261.
    10.1016/j.foodchem.2022.133261
  12. Pereira, Margarida; Silva, Filipa Cosme; Simões, Sandra; Ribeiro, Helena Margarida; Almeida, António José; Marto, Joana. "Innovative, Sugar-Free Oral Hydrogel as a Co-administrative Vehicle for Pediatrics: a Strategy to Enhance Patient Compliance". AAPS PharmSciTech 23 4 (2022): http://dx.doi.org/10.1208/s12249-022-02265-1.
    10.1208/s12249-022-02265-1
  13. Laranjeira, Tânia; Costa, Ana; Faria-Silva, Catarina; Ribeiro, Daniela; de Oliveira, José Miguel P. Ferreira; Simões, Sandra; Ascenso, Andreia. "Sustainable Valorization of Tomato By-Products to Obtain Bioactive Compounds: Their Potential in Inflammation and Cancer Management". Molecules 27 5 (2022): 1701. http://dx.doi.org/10.3390/molecules27051701.
    10.3390/molecules27051701
  14. Nakov, Ana; Magalhães, Carolina; Faria-Silva, Catarina; Ascensão, Lia; Marto, Joana; Ribeiro, Helena Margarida; Simões, Sandra. "Lipid-coated membranes as skin surrogates for permeability assessment". Materialia 21 (2022): 101354. http://dx.doi.org/10.1016/j.mtla.2022.101354.
    10.1016/j.mtla.2022.101354
  15. Cruz, Maria Eugénia Meirinhos; Corvo, Maria Luísa; Martins, Maria Bárbara; Simões, Sandra; Gaspar, Maria Manuela. "Liposomes as Tools to Improve Therapeutic Enzyme Performance". Pharmaceutics 14 3 (2022): 531. http://dx.doi.org/10.3390/pharmaceutics14030531.
    10.3390/pharmaceutics14030531
  16. Ferreira-Silva, Margarida; Faria-Silva, Catarina; Carvalheiro, Manuela C.; Simões, Sandra; Marinho, H. Susana; Marcelino, Paulo; Campos, Maria Celeste; et al. "Quercetin Liposomal Nanoformulation for Ischemia and Reperfusion Injury Treatment". Pharmaceutics 14 1 (2022): 104. http://dx.doi.org/10.3390/pharmaceutics14010104.
    10.3390/pharmaceutics14010104
  17. Sérgio P Camões; Ozlem Bulut; Volkan Yazar; Manuela Gaspar; Sandra Simões; Rita Ferreira; Rui Vitorino; et al. "3D-MSCs A151 ODN-Loaded Exosomes Are Immunomodulatory And Reveal A Proteomic Cargo That Sustains Wound Resolution". Journal of Advanced Research (2022): https://doi.org/10.1016/j.jare.2022.01.013.
    10.1016/j.jare.2022.01.013
  18. Varrica, Carla; Carvalheiro, Manuela; Faria-Silva, Catarina; Eleutério, Carla; Sandri, Giuseppina; Simões, Sandra. "Topical Allopurinol-Loaded Nanostructured Lipid Carriers: A Novel Approach for Wound Healing Management". Bioengineering 8 12 (2021): 192. http://dx.doi.org/10.3390/bioengineering8120192.
    10.3390/bioengineering8120192
  19. Cunha, Rita F.; Simões, Sandra; Carvalheiro, Manuela; Pereira, José M. Azevedo; Costa, Quirina; Ascenso, Andreia. "Novel Antiretroviral Therapeutic Strategies for HIV". Molecules 26 17 (2021): 5305. http://dx.doi.org/10.3390/molecules26175305.
    10.3390/molecules26175305
  20. Simões, Sandra; Almeida, Antonio J.; Marto, Joana. "Palatability of pediatric formulations: do rats predict aversiveness?". Drug Development and Industrial Pharmacy 47 7 (2021): 1121-1126. http://dx.doi.org/10.1080/03639045.2021.1984519.
    10.1080/03639045.2021.1984519
  21. Costa, Ana; Marques, Marta; Congiu, Franca; Paiva, Alexandre; Simões, Pedro; Ferreira, António; Bronze, Maria Rosário; et al. "Evaluating the Presence of Lycopene-Enriched Extracts from Tomato on Topical Emulsions: Physico-Chemical Characterization and Sensory Analysis". Applied Sciences 11 11 (2021): 5120. http://dx.doi.org/10.3390/app11115120.
    10.3390/app11115120
  22. Quitério, Maria; Simões, Sandra; Ascenso, Andreia; Carvalheiro, Manuela; Leandro, Ana Paula; Correia, Isabel; Viana, Ana Silveira; et al. "Development of a Topical Insulin Polymeric Nanoformulation for Skin Burn Regeneration: An Experimental Approach". International Journal of Molecular Sciences 22 8 (2021): 4087. http://dx.doi.org/10.3390/ijms22084087.
    10.3390/ijms22084087
  23. Mancini, Giuliana; Gonçalves, Lídia M. D.; Marto, Joana; Carvalho, Filomena A.; Simões, Sandra; Ribeiro, Helena Margarida; Almeida, António J.. "Increased Therapeutic Efficacy of SLN Containing Etofenamate and Ibuprofen in Topical Treatment of Inflammation". Pharmaceutics 13 3 (2021): 328. http://dx.doi.org/10.3390/pharmaceutics13030328.
    10.3390/pharmaceutics13030328
  24. Clarinda Costa; Zehua Liu; Sandra I. Simões; Alexandra Correia; Antti Rahikkala; Jani Seitsonen; Janne Ruokolainen; et al. "One-step microfluidics production of enzyme-loaded liposomes for the treatment of inflammatory diseases". Colloids and Surfaces B: Biointerfaces (2021): 111556-111556. https://doi.org/10.1016/j.colsurfb.2020.111556.
    10.1016/j.colsurfb.2020.111556
  25. Manuela Carvalheiro; Jennifer Vieira; Catarina Faria-Silva; Joana Marto; Sandra Simões. "Amphotericin B-loaded deformable lipid vesicles for topical treatment of cutaneous leishmaniasis skin lesions". Drug Delivery and Translational Research (2021): https://doi.org/10.1007/s13346-021-00910-z.
    10.1007/s13346-021-00910-z
  26. Varrica, Carla; Dias, Helena Sofia; Reis, Catarina; Carvalheiro, Manuela; Simões, Sandra. "Targeted delivery in scleroderma fibrosis". Autoimmunity Reviews 20 2 (2021): 102730. http://dx.doi.org/10.1016/j.autrev.2020.102730.
    10.1016/j.autrev.2020.102730
  27. Mota, Ana Henriques; Duarte, Noélia; Serra, Ana Teresa; Ferreira, António; Bronze, Maria Rosário; Custódio, Luísa; Gaspar, Maria Manuela; et al. "Further Evidence of Possible Therapeutic Uses of Sambucus nigra L. Extracts by the Assessment of the In Vitro and In Vivo Anti-Inflammatory Properties of Its PLGA and PCL-Based Nanoformulations". Pharmaceutics 12 12 (2020): 1181. http://dx.doi.org/10.3390/pharmaceutics12121181.
    10.3390/pharmaceutics12121181
  28. Mota, Ana Henriques; Andrade, Joana M.; Rodrigues, Maria João; Custódio, Luísa; Bronze, Maria Rosário; Duarte, Noélia; Baby, André; et al. "Synchronous insight of in vitro and in vivo biological activities of Sambucus nigra L. extracts for industrial uses". Industrial Crops and Products 154 (2020): 112709. http://dx.doi.org/10.1016/j.indcrop.2020.112709.
    10.1016/j.indcrop.2020.112709
  29. Barroso, Andreia; Mestre, Henrique; Ascenso, Andreia; Simões, Sandra; Reis, Catarina. "Nanomaterials in wound healing: From material sciences to wound healing applications". Nano Select 1 5 (2020): 443-460. http://dx.doi.org/10.1002/nano.202000055.
    10.1002/nano.202000055
  30. Nunes, Andreia; Marto, Joana; Gonçalves, Lídia Maria; Simões, Sandra; Félix, Rita; Ascenso, Andreia; Lopes, Francisca; Ribeiro, Helena Margarida. "Novel and Modified Neutrophil Elastase Inhibitor Loaded in Topical Formulations for Psoriasis Management". Pharmaceutics 12 4 (2020): 358. http://dx.doi.org/10.3390/pharmaceutics12040358.
    10.3390/pharmaceutics12040358
  31. Storozhylova, Nataliya; Crecente-Campo, José; Cabaleiro, David; Lugo, Luis; Dussouy, Christophe; Simões, Sandra; Monteiro, Madalena; Grandjean, Cyrille; Alonso, María J.. "An In Situ Hyaluronic Acid-Fibrin Hydrogel Containing Drug-Loaded Nanocapsules for Intra-Articular Treatment of Inflammatory Joint Diseases". Regenerative Engineering and Translational Medicine (2020): http://dx.doi.org/10.1007/s40883-020-00154-2.
    10.1007/s40883-020-00154-2
  32. Caseiro, Mélanie; Ascenso, Andreia; Costa, Ana; Creagh-Flynn, Jack; Johnson, Melissa; Simões, Sandra. "Lycopene in human health". LWT (2020): 109323. http://dx.doi.org/10.1016/j.lwt.2020.109323.
    10.1016/j.lwt.2020.109323
  33. André Oliveira; Sandra Simões; Andreia Ascenso; Catarina Pinto Reis. "Therapeutic advances in wound healing". Journal of Dermatological Treatment (2020): 1-77. https://doi.org/10.1080/09546634.2020.1730296.
    10.1080/09546634.2020.1730296
  34. Grenha, Ana; Alves, Ana D.; Guerreiro, Filipa; Pinho, Jacinta; Simões, Sandra; Almeida, António José; Gaspar, Maria Manuela. "Inhalable locust bean gum microparticles co-associating isoniazid and rifabutin: Therapeutic assessment in a murine model of tuberculosis infection". European Journal of Pharmaceutics and Biopharmaceutics 147 (2020): 38-44. http://dx.doi.org/10.1016/j.ejpb.2019.11.009.
    10.1016/j.ejpb.2019.11.009
  35. Faria-Silva, Catarina; Ascenso, Andreia; Costa, Ana M.; Marto, Joana; Carvalheiro, Manuela; Ribeiro, Helena Margarida; Simões, Sandra. "Feeding the skin: A new trend in food and cosmetics convergence". Trends in Food Science & Technology 95 (2020): 21-32. http://dx.doi.org/10.1016/j.tifs.2019.11.015.
    10.1016/j.tifs.2019.11.015
  36. Dogbe, Marina G.; Mafilaza, Ambinintsoa Yattussia; Eleutério, Carla Vânia; Cabral-Marques, Helena; Simões, Sandra; Gaspar, Maria Manuela. "Pharmaceutical Benefits of Fluticasone Propionate Association to Delivery Systems: In Vitro and In Vivo Evaluation". Pharmaceutics 11 10 (2019): 521. http://dx.doi.org/10.3390/pharmaceutics11100521.
    10.3390/pharmaceutics11100521
  37. Sandra Simões; Rui Lopes; Maria Celeste Dias Campos; Maria João Marruz; Maria Eugénia Meirinhos da Cruz; Luísa Corvo. "Animal models of acute gastric mucosal injury: Macroscopic and microscopic evaluation". Animal Models and Experimental Medicine (2019): https://doi.org/10.1002/ame2.12060.
    10.1002/ame2.12060
  38. Marto, Joana; Duarte, Aida; Simões, Sandra; Gonçalves, Lídia; Gouveia, Luís; Almeida, António; Ribeiro, Helena. "Starch-Based Pickering Emulsions as Platforms for Topical Antibiotic Delivery: In Vitro and In Vivo Studies". Polymers 11 1 (2019): 108. http://dx.doi.org/10.3390/polym11010108.
    10.3390/polym11010108
  39. Miranda, Joana P.; Camões, Sérgio P.; Gaspar, Maria M.; Rodrigues, Joana S.; Carvalheiro, Manuela; Bárcia, Rita N.; Cruz, Pedro; et al. "The Secretome Derived From 3D-Cultured Umbilical Cord Tissue MSCs Counteracts Manifestations Typifying Rheumatoid Arthritis". Frontiers in Immunology (2019): https://www.frontiersin.org/articles/10.3389/fimmu.2019.00018/full.
    Published • 10.3389/fimmu.2019.00018
  40. Marto, Joana; Neves, Ângela; Gonçalves, Lídia; Pinto, Pedro; Almeida, Cristina; Simões, Sandra. "Rice Water: A Traditional Ingredient with Anti-Aging Efficacy". Cosmetics 5 2 (2018): 26. http://dx.doi.org/10.3390/cosmetics5020026.
    10.3390/cosmetics5020026
  41. Marto, J.; Ruivo, E.; Lucas, S.D.; Gonçalves, L.M.; Simões, S.; Gouveia, L.F.; Felix, R.; et al. "Starch nanocapsules containing a novel neutrophil elastase inhibitor with improved pharmaceutical performance". European Journal of Pharmaceutics and Biopharmaceutics 127 (2018): 1-11. http://www.scopus.com/inward/record.url?eid=2-s2.0-85041571552&partnerID=MN8TOARS.
    10.1016/j.ejpb.2018.01.011
  42. Pivetta, T.P.; Simões, S.; Araújo, M.M.; Carvalho, T.; Arruda, C.; Marcato, P.D.. "Development of nanoparticles from natural lipids for topical delivery of thymol: Investigation of its anti-inflammatory properties". Colloids and Surfaces B: Biointerfaces 164 (2018): 281-290. http://www.scopus.com/inward/record.url?eid=2-s2.0-85041409969&partnerID=MN8TOARS.
    10.1016/j.colsurfb.2018.01.053
  43. Bárcia, R.N.; Santos, J.M.; Teixeira, M.; Filipe, M.; Pereira, A.R.S.; Ministro, A.; Água-Doce, A.; et al. "Umbilical cord tissue–derived mesenchymal stromal cells maintain immunomodulatory and angiogenic potencies after cryopreservation and subsequent thawing". Cytotherapy 19 3 (2017): 360-370. http://www.scopus.com/inward/record.url?eid=2-s2.0-85009396582&partnerID=MN8TOARS.
    10.1016/j.jcyt.2016.11.008
  44. Simões, Sandra. "Development and Characterization of a Novel Vesicular System for Topical Delivery: An Opportunity for Dimethylsulfoxide". (2016):
    doi:10.4172/2161-0444.1000354
  45. Menezes, A.C.; Raposo, S.; Simões, S.; Ribeiro, H.; Oliveira, H.; Ascenso, A.. "Prevention of Photocarcinogenesis by Agonists of 5-HT1A and Antagonists of 5-HT2A Receptors". Molecular Neurobiology 53 2 (2016): 1145-1164. http://www.scopus.com/inward/record.url?eid=2-s2.0-84958119979&partnerID=MN8TOARS.
    10.1007/s12035-014-9068-z
  46. Ascenso, A.; Pedrosa, T.; Pinho, S.; Pinho, F.; De Oliveira, J.M.P.F.; Marques, H.C.; Oliveira, H.; Simões, S.; Santos, C.. "The Effect of Lycopene Preexposure on UV-B-Irradiated Human Keratinocytes". Oxidative Medicine and Cellular Longevity 2016 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84948844263&partnerID=MN8TOARS.
    10.1155/2016/8214631
  47. Menezes, A.C.; Campos, P.M.; Euletério, C.; Simões, S.; Praça, F.S.G.; Bentley, M.V.L.B.; Ascenso, A.. "Development and characterization of novel 1-(1-Naphthyl)piperazine-loaded lipid vesicles for prevention of UV-induced skin inflammation". European Journal of Pharmaceutics and Biopharmaceutics 104 (2016): 101-109. http://www.scopus.com/inward/record.url?eid=2-s2.0-84964808114&partnerID=MN8TOARS.
    10.1016/j.ejpb.2016.04.023
  48. Simões, S.; Carvalheiro, M.; Gaspar, M.M.. "Lipid-based nanocarriers for cutaneous leishmaniais and buruli ulcer management". Current Pharmaceutical Design 22 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-85010671889&partnerID=MN8TOARS.
    10.2174/1381612822666160701083812
  49. Marto, J.; Ascenso, A.; Simoes, S.; Almeida, A.J.; Ribeiro, H.M.. "Pickering emulsions: challenges and opportunities in topical delivery". Expert Opinion on Drug Delivery 13 8 (2016): 1093-1107. http://www.scopus.com/inward/record.url?eid=2-s2.0-84978833972&partnerID=MN8TOARS.
    10.1080/17425247.2016.1182489
  50. Marto, J.; Vitor, C.; Guerreiro, A.; Severino, C.; Eleutério, C.; Ascenso, A.; Simões, S.. "Ethosomes for enhanced skin delivery of griseofulvin". Colloids and Surfaces B: Biointerfaces 146 (2016): 616-623. http://www.scopus.com/inward/record.url?eid=2-s2.0-84989826171&partnerID=MN8TOARS.
    10.1016/j.colsurfb.2016.07.021
  51. Ascenso, A.; Raposo, S.; Batista, C.; Cardoso, P.; Mendes, T.; Praça, F.G.; Bentley, M.V.L.B.; Simões, S.. "Development, characterization, and skin delivery studies of related ultradeformable vesicles: Transfersomes, ethosomes, and transethosomes". International Journal of Nanomedicine 10 (2015): 5837-5851. http://www.scopus.com/inward/record.url?eid=2-s2.0-84942279308&partnerID=MN8TOARS.
    10.2147/IJN.S86186
  52. Bárcia, R.N.; Santos, J.M.; Filipe, M.; Teixeira, M.; Martins, J.P.; Almeida, J.; Água-Doce, A.; et al. "What makes umbilical cord tissue-derived mesenchymal stromal cells superior immunomodulators when compared to bone marrow derived mesenchymal stromal cells?". Stem Cells International 2015 (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84930686279&partnerID=MN8TOARS.
    10.1155/2015/583984
  53. Marto, J.; Baltazar, D.; Duarte, A.; Fernandes, A.; Gouveia, L.; Militão, M.; Salgado, A.; et al. "Topical gels of etofenamate: in vitro and in vivo evaluation". Pharmaceutical Development and Technology 20 6 (2015): 710-715. http://www.scopus.com/inward/record.url?eid=2-s2.0-84964238161&partnerID=MN8TOARS.
    10.3109/10837450.2014.915571
  54. Raposo, S.; Tavares, R.; Gonçalves, L.; Simões, S.; Urbano, M.; Ribeiro, H.M.. "Mometasone furoate-loaded cold processed oil-in-water emulsions: In vitro and in vivo studies". Drug Delivery 22 4 (2015): 562-572. http://www.scopus.com/inward/record.url?eid=2-s2.0-84933527394&partnerID=MN8TOARS.
    10.3109/10717544.2013.871086
  55. Santos, J.M.; Camões, S.P.; Filipe, E.; Cipriano, M.; Barcia, R.N.; Filipe, M.; Teixeira, M.; et al. "Three-dimensional spheroid cell culture of umbilical cord tissue-derived mesenchymal stromal cells leads to enhanced paracrine induction of wound healing". Stem Cell Research and Therapy 6 1 (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84930684508&partnerID=MN8TOARS.
    10.1186/s13287-015-0082-5
  56. Ascenso, A.; Ribeiro, H.; Marques, H.C.; Oliveira, H.; Santos, C.; Simões, S.. "Is tretinoin still a key agent for photoaging management?". Mini-Reviews in Medicinal Chemistry 14 8 (2014): 629-641. http://www.scopus.com/inward/record.url?eid=2-s2.0-84906907817&partnerID=MN8TOARS.
    10.2174/1389557514666140820102735
  57. Ascenso, A.; Salgado, A.; Euletério, C.; Praça, F.G.; Bentley, M.V.L.B.; Marques, H.C.; Oliveira, H.; Santos, C.; Simões, S.. "In vitro and in vivo topical delivery studies of tretinoin-loaded ultradeformable vesicles". European Journal of Pharmaceutics and Biopharmaceutics 88 1 (2014): 48-55. http://www.scopus.com/inward/record.url?eid=2-s2.0-84934282691&partnerID=MN8TOARS.
    10.1016/j.ejpb.2014.05.002
  58. Salgado, A.; Raposo, S.; Marto, J.; Silva, A.N.; Simões, S.; Ribeiro, H.M.. "Mometasone furoate hydrogel for scalp use: In vitro and in vivo evaluation". Pharmaceutical Development and Technology 19 5 (2014): 618-622. http://www.scopus.com/inward/record.url?eid=2-s2.0-84899807412&partnerID=MN8TOARS.
    10.3109/10837450.2013.819012
  59. Ascenso, A.; Ribeiro, H.; Marques, H.C.; Oliveira, H.; Santos, C.; Simões, S.. "Chemoprevention of photocarcinogenesis by lycopene". Experimental Dermatology 23 12 (2014): 874-878. http://www.scopus.com/inward/record.url?eid=2-s2.0-84914174838&partnerID=MN8TOARS.
    10.1111/exd.12491
  60. Raposo, S.C.; Simões, S.D.; Almeida, A.J.; Ribeiro, H.M.. "Advanced systems for glucocorticoids' dermal delivery". Expert Opinion on Drug Delivery 10 6 (2013): 857-877. http://www.scopus.com/inward/record.url?eid=2-s2.0-84878054508&partnerID=MN8TOARS.
    10.1517/17425247.2013.778824
  61. Ascenso, A.; Cruz, M.; Euletério, C.; Carvalho, F.A.; Santos, N.C.; Marques, H.C.; Simões, S.. "Novel tretinoin formulations: A drug-in-cyclodextrin-in-liposome approach". Journal of Liposome Research 23 3 (2013): 211-219. http://www.scopus.com/inward/record.url?eid=2-s2.0-84880463944&partnerID=MN8TOARS.
    10.3109/08982104.2013.788026
  62. Ascenso, A.; Pinho, S.; Eleutério, C.; Praça, F.G.; Bentley, M.V.L.B.; Oliveira, H.; Santos, C.; Silva, O.; Simões, S.. "Lycopene from tomatoes: Vesicular nanocarrier formulations for dermal delivery". Journal of Agricultural and Food Chemistry 61 30 (2013): 7284-7293. http://www.scopus.com/inward/record.url?eid=2-s2.0-84881080237&partnerID=MN8TOARS.
    10.1021/jf401368w
  63. Santos, J.M.; Bárcia, R.N.; Simões, S.I.; Gaspar, M.M.; Calado, S.; Água-Doce, A.; Almeida, S.C.P.; et al. "The role of human umbilical cord tissue-derived mesenchymal stromal cells (UCX®) in the treatment of inflammatory arthritis". Journal of Translational Medicine 11 1 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84872268288&partnerID=MN8TOARS.
    10.1186/1479-5876-11-18
  64. Ascenso, A.; Vultos, F.; Ferrinho, D.; Salgado, A.; Filho, S.G.; Ferrari, V.; Simões, S.; Marques, H.C.. "Effect of tretinoin inclusion in dimethyl-beta-cyclodextrins on release rate from a hydrogel formulation". Journal of Inclusion Phenomena and Macrocyclic Chemistry 73 1-4 (2012): 459-465. http://www.scopus.com/inward/record.url?eid=2-s2.0-84862621735&partnerID=MN8TOARS.
    10.1007/s10847-011-0002-y
  65. Carneiro, R.; Salgado, A.; Raposo, S.; Marto, J.; Simões, S.; Urbano, M.; Ribeiro, H.M.. "Topical emulsions containing ceramides: Effects on the skin barrier function and anti-inflammatory properties". European Journal of Lipid Science and Technology 113 8 (2011): 961-966. http://www.scopus.com/inward/record.url?eid=2-s2.0-80051702336&partnerID=MN8TOARS.
    10.1002/ejlt.201000495
  66. Ascenso, A.; Ribeiro, H.M.; Marques, H.C.; Simões, S.. "Topical delivery of antioxidants". Current Drug Delivery 8 6 (2011): 640-660. http://www.scopus.com/inward/record.url?eid=2-s2.0-80054119415&partnerID=MN8TOARS.
    10.2174/156720111797635487
  67. Mulchande, J.; Simões, S.I.; Gaspar, M.M.; Eleutéio, C.V.; Oliveira, R.; Cruz, M.E.M.; Moreira, R.; Iley, J.. "Synthesis, stability, biochemical and pharmacokinetic properties of a new potent and selective 4-oxo-ß-lactam inhibitor of human leukocyte elastase". Journal of Enzyme Inhibition and Medicinal Chemistry 26 2 (2011): 169-175. http://www.scopus.com/inward/record.url?eid=2-s2.0-79952059337&partnerID=MN8TOARS.
    10.3109/14756366.2010.486794
  68. Simões, S.; Marques, C.; Cruz, M.E.; Figueira Martins, M.B.. "Anti-inflammatory effects of locally applied enzyme-loaded ultradeformable vesicles on an acute cutaneous model". Journal of Microencapsulation 26 7 (2009): 649-658. http://www.scopus.com/inward/record.url?eid=2-s2.0-70449338210&partnerID=MN8TOARS.
    10.3109/02652040802630403
  69. Simões, S.I.; Tapadas, J.M.; Marques, C.M.; Cruz, M.E.M.; Martins, M.B.F.; Cevc, G.. "Permeabilisation and solubilisation of soybean phosphatidylcholine bilayer vesicles, as membrane models, by polysorbate, Tween 80". European Journal of Pharmaceutical Sciences 26 3-4 (2005): 307-317. http://www.scopus.com/inward/record.url?eid=2-s2.0-24644440552&partnerID=MN8TOARS.
    10.1016/j.ejps.2005.07.002
  70. Simões, S.I.; Delgado, T.C.; Lopes, R.M.; Jesus, S.; Ferreira, A.A.; Morais, J.A.; Cruz, M.E.M.; Corvo, M.L.; Martins, M.B.F.. "Developments in the rat adjuvant arthritis model and its use in therapeutic evaluation of novel non-invasive treatment by SOD in Transfersomes". Journal of Controlled Release 103 2 (2005): 419-434. http://www.scopus.com/inward/record.url?eid=2-s2.0-14844292727&partnerID=MN8TOARS.
    10.1016/j.jconrel.2004.12.008
  71. Simões, S.I.D.; Eleutério, C.V.; Cruz, M.E.M.; Corvo, M.L.; Martins, M.B.F.. "Biochemical changes in arthritic rats: Dehydroascorbic and ascorbic acid levels". European Journal of Pharmaceutical Sciences 18 2 (2003): 185-189. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037317115&partnerID=MN8TOARS.
    10.1016/S0928-0987(02)00258-0
  72. Martins, M.B.F.; Supico, A.; Simões, S.I.D.; Gaspar, R.; Cruz, M.E.M.. "An analytical methodology to quantify the incorporation of enzymes in polyalkylcyanoacrylate nanoparticles based on size exclusion chromatography". Journal of Pharmaceutical and Biomedical Analysis 15 6 (1997): 811-818. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030998134&partnerID=MN8TOARS.
    10.1016/S0731-7085(96)01909-7
  73. Simoes, S.I.; Martins, M.B.; Cruz, M.E.. "Enzyme-loaded soybean phosphatidylcholine and sodium deoxycholate aggregates: Preparation and characterization". Proceedings of the Controlled Release Society 24 (1997): 723-724. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030875539&partnerID=MN8TOARS.
  74. Martins, M.B.F.; Simões, S.I.D.; Supico, A.; Cruz, M.E.M.; Gaspar, R.. "Enzyme-loaded PIBCA nanoparticles (SOD and L-ASNase): Optimization and characterization". International Journal of Pharmaceutics 142 1 (1996): 75-84. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030604044&partnerID=MN8TOARS.
    10.1016/0378-5173(96)04652-2
  75. Martins, M.B.F.; Simões, S.I.D.; Cruz, M.E.M.; Caspar, R.. "Development of enzyme-loaded nanoparticles: Effect of pH". Journal of Materials Science: Materials in Medicine 7 7 (1996): 413-414. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030200027&partnerID=MN8TOARS.
    10.1007/BF00122010
Magazine article
  1. Simões, Sandra. "Rice water in cosmetics: the benefits for skin", H&PC Today - Household and Personal Care Today , 2019, https://mail.google.com/mail/u/0/?tab=wm&ogbl#search/rice+water/KtbxLvgxBHSNpTxgvBvTrZTMmdZwNlVvSB?projector=1&messagePartId=0.1.
Online resource
  1. Simões, Sandra. Por que vem o meu produto cosmético numa ampola?. 2019. https://www.publico.pt/2019/04/24/impar/opiniao/vem-produto-cosmetico-ampola-1866852.
  2. Simões, Sandra. Uso de protetor solar e produção de vitamina D: o que interessa saber. 2018. https://www.publico.pt/2018/11/28/impar/opiniao/uso-protetor-solar-producao-vitamina-d-interessa-saber-1852721.
  3. Simões, Sandra. Retinol: a "molécula mágica" contra o envelhecimento. 2018. https://www.publico.pt/2018/04/02/impar/opiniao/retinol-a-molecula-magica-contra-o-envelhecimento-1805996.

Intellectual property

Patent
  1. Simões, Sandra. 2013. "Design of a nose-only-chamber, for several animals simultaneously, promoting the targeted pulmonary administration of dry powder formulations.". Portugal.
Activities

Association member

Society Organization name Role
2017 - Current Sociedade Portuguesa de Ciências em Animais de Laboratório (SPCAL)
2015 - Current European Epidermal Barrier Research Network (E2BRN)
1998 - Current Controlled Release Society (CRS)
1996 - Current Spanish Portuguese Local Chapter of the Controlled Release Society (SPLC-CRS)

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2021/01/04 - 2021/01/12 Curso FFULisboa-SPCAL de Categoria B de Ciências em Animais de Laboratório (3ª edição-grupo B) Curso FFULisboa-SPCAL de Categoria B de Ciências em Animais de Laboratório (Curso de Especialização Tecnológica) Universidade de Lisboa Faculdade de Farmácia, Portugal
2020 - 2021 Tecnologia Farmacêutica II - Mestrado Integrado em Ciências Farmacêuticas Mestrado Integrado em Ciências Farmacêuticas (Ensino secundário) Universidade de Lisboa Faculdade de Farmácia, Portugal
2020/11/23 - 2020/12/02 Curso FFULisboa-SPCAL de Categoria B de Ciências em Animais de Laboratório (3ª edição- grupo A) (Curso de Especialização Tecnológica) Universidade de Lisboa Faculdade de Farmácia, Portugal
2019 - 2020 Tecnologia Farmacêutica II - Mestrado Integrado em Ciências Farmacêuticas (Mestrado integrado) Universidade de Lisboa Faculdade de Farmácia, Portugal
2019/09/16 - 2019/09/20 Curso FFULisboa-SPCAL de Categoria B de Ciências em Animais de Laboratório (2ª edição) (Pós-Graduação) Universidade de Lisboa Faculdade de Farmácia, Portugal
2019/03/26 - 2019/07/17 4º edição do curso b-learning de Cosmetologia Avançada (Pós-Graduação) Universidade de Lisboa Faculdade de Farmácia, Portugal
2016 - 2019 Overcoming the skin barrier FCT PhD PROGRAM IN MEDICINES AND PHARMACEUTICAL INNOVATION (I3DU) FACULDADE DE FARMÁCIA, UNIVERSIDADE DE LISBOA (Curso de doutoramento (conclusão de unidades curriculares)) Universidade de Lisboa Faculdade de Farmácia, Portugal
2018/09/10 - 2018/09/13 Curso FFULisboa-SPCAL de Categoria B de Ciências em Animais de Laboratório (1ª edição) (Pós-Graduação) Universidade de Lisboa Faculdade de Farmácia, Portugal
2009 - 2018 Farmácia Galénica - Mestrado Integrado em Ciências Farmacêuticas (Mestrado integrado) Universidade de Lisboa Faculdade de Farmácia, Portugal
2017/03/10 - 2017/06/28 2º edição do curso b-learning de Cosmetologia Avançada (Pós-Graduação) Universidade de Lisboa Faculdade de Farmácia, Portugal
2016/03/16 - 2016/06/27 1ª edição do curso b-learning de Cosmetologia Avançada (Pós-Graduação) Universidade de Lisboa Faculdade de Farmácia, Portugal
2012/03/15 - 2012/03/16 Curso PELE e FORMULAÇÃO (Pós-Graduação) Universidade de Lisboa Faculdade de Farmácia, Portugal
Distinctions

Award

2019 Prémio Científico "Prof. Doutor Aluísio Marques Leal - 2019"
Associação Portuguesa de Farmacêuticos Hospitalares , Portugal

Other distinction

1994 Prémio Sociedade Farmacêutica Lusitana
Ordem dos Farmaceuticos, Portugal
1991 Melhor Aluno de Imunologia