???global.info.a_carregar???
Identification

Personal identification

Full name
António José Abrantes Guedes da Fonseca Pereira

Author identifiers

Ciência ID
4016-40EA-B364
ORCID iD
0000-0002-1053-8715
Affiliation

Science

Category
Host institution 		Employer
2020/07/01 - 2026/06/30 Auxiliary Researcher (Research) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2016/05/01 - 2020/06/30 Auxiliary Researcher (Research) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2011/05/02 - 2019/02/01 Researcher (Research) Universidade do Porto, Portugal
2000/03/01 - 2000/06/01 Researcher (Research) Universidade do Porto Faculdade de Ciências, Portugal

Teaching in Higher Education

Category
Host institution 		Employer
2003/01/01 - 2003/06/30 Lecturer (University Teacher) Universidade do Minho - Campus de Azurém, Portugal
Universidade do Minho - Campus de Azurém, Portugal
2000/01/01 - 2000/06/30 Lecturer (University Teacher) Universidade do Minho, Portugal
Universidade do Minho, Portugal

Others

Category
Host institution 		Employer
2011/01/01 - 2015/12/31 Investigador Assistente Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2005/03/01 - 2010/12/01 Investigador (Bolseiro) Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2003/12/01 - 2004/12/01 Investigador (Bolseiro) Universidade do Minho, Portugal
2000/11/01 - 2003/08/01 Investigador (Bolseiro) Universidade do Minho, Portugal
Projects

Grant

Designation Funders
2023/01/01 - 2025/12/31 Amplifying RI impact with a global perspective: a Regional Hubs model
EU-LAC-2022-156
Invited Scientist Fellow
Ongoing

Contract

Designation Funders
2019/10/01 - Current CRACKING THE CODE BEHIND MITOTIC FIDELITY: the roles of tubulin post-translational modifications and a chromosome separation checkpoint
info:eu-repo/grantAgreement/EC/H2020/681443/EU
 European Commission
Ongoing
2022/01/01 - 2023/12/31 Pre- and post-detection strategies for STED super-resolution imaging of living cells.
EXPL/NAN-OPT/0476/2021
10.54499/EXPL/NAN-OPT/0476/2021
Principal investigator
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Universidade do Minho, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2016/05/01 - 2019/09/30 Advancing cancer research: from basic knowledge to application
NORTE-01-0145-FEDER-000029
Research Fellow
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Concluded
Outputs

Publications

Book
  1. Barisic, M.; Pereira, A.J.; Maiato, H.. Fluorescent speckle microscopy in cultured cells. 2012.
    10.1016/B978-0-12-391857-4.00007-0
  2. Pereira, A.J.; Matos, I.; Lince-Faria, M.; Maiato, H.. Dissecting mitosis with laser microsurgery and RNAi in drosophila cells. 2009.
    10.1007/978-1-60327-993-2_9
Conference paper
  1. Gomes, J.V.; Pereira, A.G.; Belsley, M.. "Geometric limits to phase matching in self-diffraction experiments". 2002.
    10.1117/12.475905
Journal article
  1. Tália Feijão; Bruno Marques; Rui D. Silva; Célia Carvalho; Daniel Sobral; Ricardo Matos; Tian Tan; et al. "Polycomb group (PcG) proteins prevent the assembly of abnormal synaptonemal complex structures during meiosis". Proceedings of the National Academy of Sciences (2022): https://doi.org/10.1073/pnas.2204701119.
    10.1073/pnas.2204701119
  2. Steblyanko, Yulia; Rajendraprasad, Girish; Osswald, Mariana; Eibes, Susana; Jacome, Ariana; Geley, Stephan; Pereira, António J; Maiato, Helder; Barisic, Marin. "Microtubule poleward flux in human cells is driven by the coordinated action of four kinesins". The EMBO Journal 39 23 (2020): http://dx.doi.org/10.15252/embj.2020105432.
    10.15252/embj.2020105432
  3. Costa, Ana Rita; Sousa, Sara C; Pinto-Costa, Rita; Mateus, José C; Lopes, Cátia DF; Costa, Ana Catarina; Rosa, David; et al. "The membrane periodic skeleton is an actomyosin network that regulates axonal diameter and conduction". eLife 9 (2020): http://dx.doi.org/10.7554/elife.55471.
    Open access • Published • 10.7554/elife.55471
  4. Ferreira, Luísa T.; Orr, Bernardo; Rajendraprasad, Girish; Pereira, António J.; Lemos, Carolina; Lima, Joana T.; Guasch Boldú, Clàudia; et al. "a-Tubulin detyrosination impairs mitotic error correction by suppressing MCAK centromeric activity". Journal of Cell Biology 219 4 (2020): http://dx.doi.org/10.1083/jcb.201910064.
    10.1083/jcb.201910064
  5. António Pereira; Mafalda Sousa; Ana C. Almeida; Luísa T. Ferreira; Ana Rita Costa; Marco Novais-Cruz; Cristina Ferrás; et al. "Coherent-hybrid STED: high contrast sub-diffraction imaging using a bi-vortex depletion beam". Optics Express (2019): https://doi.org/10.1364/OE.27.008092.
    10.1364/OE.27.008092
  6. Swadhin Chandra Jana; Susana Mendonça; Pedro Machado; Sascha Werner; Jaqueline Rocha; António Pereira; Helder Maiato; Mónica Bettencourt-Dias. "Differential regulation of transition zone and centriole proteins contributes to ciliary base diversity". Nature Cell Biology 20 8 (2018): 928-941. https://doi.org/10.1038/s41556-018-0132-1.
    10.1038/s41556-018-0132-1
  7. Moura, M.; Osswald, M.; Leça, N.; Barbosa, J.; Pereira, A.J.; Maiato, H.; Sunkel, C.E.; Conde, C.. "Protein phosphatase 1 inactivates Mps1 to ensure efficient spindle assembly checkpoint silencing". eLife 6 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85019849461&partnerID=MN8TOARS.
    10.7554/eLife.25366
  8. Maiato, H.; Pereira, A.J.. "Cell Division: NuMA Bears the Load in the Spindle". Current Biology 27 15 (2017): R765-R767. http://www.scopus.com/inward/record.url?eid=2-s2.0-85027507671&partnerID=MN8TOARS.
    10.1016/j.cub.2017.06.060
  9. Ana M. Silva; Daniel S. Osório; Antonio J. Pereira; Helder Maiato; Inês Mendes Pinto; Boris Rubinstein; Reto Gassmann; Ivo Andreas Telley; Ana Xavier Carvalho. "Robust gap repair in the contractile ring ensures timely completion of cytokinesis". The Journal of Cell Biology 215 6 (2016): 789-799. https://doi.org/10.1083/jcb.201605080.
    10.1083/jcb.201605080
  10. Pereira, António. "Inducible fluorescent speckle microscopy". The Journal of Cell Biology (2016):
    10.1083/jcb.201506128
  11. Drpic, D.; Pereira, A.J.; Barisic, M.; Maresca, T.J.; Maiato, H.. "Polar Ejection Forces Promote the Conversion from Lateral to End-on Kinetochore-Microtubule Attachments on Mono-oriented Chromosomes". Cell Reports 13 3 (2015): 460-468. http://www.scopus.com/inward/record.url?eid=2-s2.0-84944683483&partnerID=MN8TOARS.
    10.1016/j.celrep.2015.08.008
  12. O. Afonso; I. Matos; A. J. Pereira; P. Aguiar; M. A. Lampson; H. Maiato. "Feedback control of chromosome separation by a midzone Aurora B gradient". Science 345 6194 (2014): 332-336. http://dx.doi.org/10.1126/science.1251121.
    10.1126/science.1251121
  13. Ferreira, J.G.; Pereira, A.J.; Akhmanova, A.; Maiato, H.. "Aurora B spatially regulates EB3 phosphorylation to coordinate daughter cell adhesion with cytokinesis". Journal of Cell Biology 201 5 (2013): 709-724. http://www.scopus.com/inward/record.url?eid=2-s2.0-84878560571&partnerID=MN8TOARS.
    10.1083/jcb.201301131
  14. Pereira, A.J.; Maiato, H.. "Maturation of the kinetochore-microtubule interface and the meaning of metaphase". Chromosome Research 20 5 (2012): 563-577. http://www.scopus.com/inward/record.url?eid=2-s2.0-84864866423&partnerID=MN8TOARS.
    10.1007/s10577-012-9298-8
  15. Wandke, C.; Barisic, M.; Sigl, R.; Rauch, V.; Wolf, F.; Amaro, A.C.; Tan, C.H.; et al. "Human chromokinesins promote chromosome congression and spindle microtubule dynamics during mitosis". Journal of Cell Biology 198 5 (2012): 847-863. http://www.scopus.com/inward/record.url?eid=2-s2.0-84866362654&partnerID=MN8TOARS.
    10.1083/jcb.201110060
  16. Pires, L.R.; Oliveira, H.; Barrias, C.C.; Sampaio, P.; Pereira, A.J.; Maiato, H.; Simões, S.; Pêgo, A.P.. "Imidazole-grafted chitosan-mediated gene delivery: In vitro study on transfection, intracellular trafficking and degradation". Nanomedicine 6 9 (2011): 1499-1512. http://www.scopus.com/inward/record.url?eid=2-s2.0-81255143263&partnerID=MN8TOARS.
    10.2217/nnm.11.51
  17. Olszak, A.M.; Van Essen, D.; Pereira, A.J.; Diehl, S.; Manke, T.; Maiato, H.; Saccani, S.; Heun, P.. "Heterochromatin boundaries are hotspots for de novo kinetochore formation". Nature Cell Biology 13 7 (2011): 799-808. http://www.scopus.com/inward/record.url?eid=2-s2.0-79960028125&partnerID=MN8TOARS.
    10.1038/ncb2272
  18. Pereira, A.J.; Maiato, H.. "Improved kymography tools and its applications to mitosis". Methods 51 2 (2010): 214-219. http://www.scopus.com/inward/record.url?eid=2-s2.0-77953120488&partnerID=MN8TOARS.
    10.1016/j.ymeth.2010.01.016
  19. Reis, R.; Feijão, T.; Gouveia, S.; Pereira, A.J.; Matos, I.; Sampaio, P.; Maiato, H.; Sunkel, C.E.. "Dynein and Mast/Orbit/CLASP have antagonistic roles in regulating kinetochore-microtubule plus-end dynamics". Journal of Cell Science 122 14 (2009): 2543-2553. http://www.scopus.com/inward/record.url?eid=2-s2.0-69649098888&partnerID=MN8TOARS.
    10.1242/jcs.044818
  20. Matos, I.; Pereira, A.J.; Lince-Faria, M.; Cameron, L.A.; Salmon, E.D.; Maiato, H.. "Synchronizing chromosome segregation by flux-dependent force equalization at kinetochores". Journal of Cell Biology 186 1 (2009): 11-26. http://www.scopus.com/inward/record.url?eid=2-s2.0-67650479043&partnerID=MN8TOARS.
    10.1083/jcb.200904153
  21. Pereira, A.L.; Pereira, A.J.; Maia, A.R.R.; Drabek, K.; Sayas, C.L.; Hergert, P.J.; Lince-Faria, M.; et al. "Mammalian CLASP1 and CLASP2 cooperate to ensure mitotic fidelity by regulating spindle and kinetochore function". Molecular Biology of the Cell 17 10 (2006): 4526-4542. http://www.scopus.com/inward/record.url?eid=2-s2.0-33749480148&partnerID=MN8TOARS.
    10.1091/mbc.E06-07-0579
  22. Pereira, A.; Ferreira, F.; Belsley, M.. "Using light scattering to measure the temporal coherence of optical sources". Journal of the Optical Society of America A: Optics and Image Science, and Vision 22 1 (2005): 93-102. http://www.scopus.com/inward/record.url?eid=2-s2.0-12844261201&partnerID=MN8TOARS.
    10.1364/JOSAA.22.000093
Activities

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2022/01/01 - Current Dissecting the mechanism that governs metaphase chromosome positioning in mammals
Co-supervisor
 Doutoramento em Ciências Biomédicas (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Distinctions

Award

2015 'Young Biophysicist Award' by the Portuguese Biophysics Society
Portuguese Biophysics Society (https://www.spbf.pt/), Portugal
2014 Prémio Pfizer 2014 - Investigação Básica (ex-aequo, 2 research works; first author, Olga Afonso; group leader, Helder Maiato))
Pfizer AG & Sociedade de Ciências Médicas de Lisboa , Portugal
2006 Analytical and Quantitative Light Microscopy: David Wolf course distinction (ex-aequo, 3 alumni)
Marine Biological Laboratory, United States
2005 InventUminho (2nd prize); with Flávio P. Ferreira (University of Minho)
TecMinho Associação Universidade-Empresa para o Desenvolvimento, Portugal
2003 OSA - Laser Optics for Young Scientists 2003, Best Paper Award, St. Petersburg, Russia
Optical Society of America, United States