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Joana Margarida Verdasca Jorge is a PhD student at the Doctoral Programme in Health Sciences of the Faculty of Medicine of University of Coimbra, holding a PhD scholarship funded by FCT. She has a master's degree in Biochemistry (2014) and a degree in Biology (2011) both in Faculty of Sciences and Technology, University of Coimbra. She is a researcher in Coimbra Institute for Clinical and Biomedical Research (iCBR) - Group of Environment Genetics and Oncobiology (CIMAGO) of FMUC and Centre for Innovative Biomedicine and Biotechnology Consortium (CIBB). She is a member of several societies, namely the European Association for Cancer Research (EACR), European Hematology Association (EHA) and Portuguese Association for Cancer Research (ASPIC). Joana Jorge published 24 journal articles (4 as the first author), 5 book chapters, and over 80 abstracts in international and national journals (h-index 10 and 354 citations). She presented more than 170 works in scientific meetings (132 poster presentations and 45 oral communications). She received 18 awards/distinctions. She co-supervised 5 MSc students (1 ongoing) and provides laboratory support for students' investigation projects or in investigation curricular units.
Identification

Personal identification

Full name
Joana Margarida Verdasca Jorge

Citation names

  • Jorge, Joana

Author identifiers

Ciência ID
4018-E914-BD91
ORCID iD
0000-0003-0755-8077
Researcher Id
F-2454-2019
Scopus Author Id
56954472900

Email addresses

  • jjorge@fmed.uc.pt (Professional)
  • joanaverdasca@gmail.com (Personal)

Addresses

  • Coimbra Institute for Clinical and Biomedical Research, Azinhaga Santa Comba, Celas, 3000-548, Celas, Coimbra, Portugal (Professional)

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
French Elementary (A2) Intermediate (B1) Beginner (A1) Beginner (A1)
Education
Degree Classification
2019 - 2024
Ongoing
Doctoral programme in Health Sciences (Doutoramento)
University of Coimbra, Faculty of Medicine, Portugal
2023/06/12 - 2023/07/29
Concluded
Proteotranscriptomic profiling of mature B-cell neoplasms for the detection of biomarkers associated with patient response and resistance (Outros)
Centro de Investigación del Cáncer, Universidad de Salamanca, Spain
2023/03 - 2023/03
Concluded
Theoretical and Practical Course “Flow cytometry and cell sorting - From Basics Concepts to Artificial Intelligence applied to Data Analysis” (Outros)
Universidade de Coimbra Faculdade de Medicina, Portugal
2022/02
Concluded
4th Edition of Citogenetic and Genomic in diagnosis and research (Outros)
Universidade de Coimbra Faculdade de Medicina, Portugal
2021/07
Concluded
Rome Training School - Targeting MDR Tumours: from natural product chemistry to nanocarrier-based formulation (Outros)
Sapienza University of Rome - Department Drug Chemistry and Technologies, Italy
2020/11 - 2020/11
Concluded
Modular Training in Laboratory Animal Science (Outros)
Major in Function A, B, SS
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Coimbra Institute for Clinical and Biomedical Research, Portugal
2019/12 - 2019/12
Concluded
Theoretical and practical course "Monitorização do Sistema imune: relevância no diagnóstico das IDP e na resposta à imunoterapia em hemopatias malignas" (Outros)
Centro Hospitalar e Universitário de Coimbra EPE, Portugal
2019/05 - 2019/05
Concluded
Training Course in Planning of Research Projects (Outros)
Universidade de Coimbra Faculdade de Medicina, Portugal
2018/01/08 - 2018/01/12
Concluded
International Intensive Course on Cancer Biology – Advances in epidemiology, etiology and therapy (Outros)
Universidade do Porto Faculdade de Farmácia, Portugal
2017/11/20 - 2017/11/21
Concluded
Theoretical and practical course “Novos avanços Euroflow em base de dados e no diagnóstico de neoplasias de células B” (Outros)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2017/09/28 - 2017/09/30
Concluded
Hands-on Workshop on Image Analysis for Imaging Flow Cytometry (Outros)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
19
2017/06/06 - 2017/06/08
Concluded
Training Course - QuantStudio® HRM Calibration, Software and applications - Set-up and analysis (Outros)
Universidade de Coimbra Faculdade de Medicina, Portugal

Thermo Fisher Scientific Inc, United States
2016/03 - 2016/03
Concluded
Course “Statistic with SPSS” (Outros)
Universidade de Coimbra Faculdade de Medicina, Portugal
2016/02
Concluded
Course “New advances in Flow Cytometry Diagnosis" (Outros)
Centro Hospitalar e Universitário de Coimbra EPE, Portugal
2014/10
Concluded
Course "Molecular Oncology: Cancer Biology and Emerging Therapies" (Outros)
Instituto Português de Oncologia de Coimbra Francisco Gentil EPE, Portugal
2014/03/31
Concluded
Biochemistry (Mestrado)
University of Coimbra, Faculty of Sciences and Technology, Portugal
"Avaliação do perfil de metilação em Síndrome Mielodisplásica - Estudo comparativo entre sangue periférico e medula óssea" (THESIS/DISSERTATION)
16 valores
2013/07
Concluded
Cell Culture and Tissue Course “Beyond and Microscope, culturing Life” (Outros)
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia, Portugal
2011/07/05
Concluded
Biology (Licenciatura)
University of Coimbra, Faculty of Medicine, Portugal
"N. A." (THESIS/DISSERTATION)
12.298
Affiliation

Science

Category
Host institution
Employer
2016/01/02 - Current Research Trainee (Research) Coimbra Institute for Clinical and Biomedical Research (iCBR) – Group of Environment, Genetics and Oncobiology (CIMAGO) - Faculty of Medicine, University of Coimbra, Portugal
2015/01/01 - 2015/12/31 Research Trainee (Research) Liga Portuguesa Contra o Cancro Núcleo Regional do Centro, Portugal

Teaching in Higher Education

Category
Host institution
Employer
2019/12 - 2023/07 Invited Assistant (University Teacher) Universidade de Coimbra Faculdade de Medicina, Portugal
2016/09/05 - 2017/02/05 Invited Assistant (University Teacher) Universidade de Coimbra Faculdade de Medicina, Portugal

Others

Category
Host institution
Employer
2020 - Current PhD student University of Coimbra, Faculty of Medicine, Portugal
Projects

Grant

Designation Funders
2021/02 - Current Clinical relevance of platelets as non-invasive biomarkers in diffuse large B-cell lymphoma - A pilot study
NRC-LPCC/CIMAGO 2020,
Researcher
Liga Portuguesa Contra o Cancro Núcleo Regional do Centro, Portugal
Ongoing

Contract

Designation Funders
2020/01/01 - 2023/12/31 Clinical relevance of platelets in mature B cell neoplasms: Role as non-invasive biomarkers and therapeutic delivery systems
SFRH/BD/145531/2019
PhD Student Fellow
Universidade de Coimbra, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2015/01/01 - 2015/12/31 Modulação redox em neoplasias hematológicas - O NRF2 como novo marcador e alvo terapêutico
LPCC-NRC/CIMAGO 2015
Master Student Fellow
Liga Portuguesa Contra o Cancro Núcleo Regional do Centro, Portugal

Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia, Portugal
Concluded

Other

Designation Funders
2022/01 - Current Synthetic lethality in acute myeloid leukemia – Role of DNA damage response
CIMAGO 04/22
Researcher
Coimbra Institute for Clinical and Biomedical Research (iCBR) – Group of Environment, Genetics and Oncobiology (CIMAGO) - Faculty of Medicine, University of Coimbra, Portugal
Ongoing
2022/01 - Current Evaluation of molecular mechanisms of resistance to proteasome inhibitors and immunomodulatory drugs in multiple myeloma
CIMAGO 05/22
Researcher
Coimbra Institute for Clinical and Biomedical Research (iCBR) – Group of Environment, Genetics and Oncobiology (CIMAGO) - Faculty of Medicine, University of Coimbra, Portugal
Ongoing
2022/01 - Current The role of platelets in diagnosis, prognosis and therapeutic monitoring in diffuse large B-cell lymphoma
CIMAGO 06/22
Researcher
Coimbra Institute for Clinical and Biomedical Research (iCBR) – Group of Environment, Genetics and Oncobiology (CIMAGO) - Faculty of Medicine, University of Coimbra, Portugal
Ongoing
2022/01 - Current HemaCirc: CircRNAs as an innovative tool in hematological neoplasms
CIMAGO 08/22
Researcher
Coimbra Institute for Clinical and Biomedical Research (iCBR) – Group of Environment, Genetics and Oncobiology (CIMAGO) - Faculty of Medicine, University of Coimbra, Portugal
Ongoing
2018/01/01 - Current NRF2-KEAP1 axis as a new potential prognostic biomarker in chronic lymphocytic leukemia
Project 03/18
Researcher
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia, Portugal
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia
Ongoing
2018/01/01 - Current Identification of new response markers to Bortezomib and Lenalidomide in patients with multiple myeloma - The role of NF-kB and NRF2/KEAP1
Project 04/18
Researcher
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia, Portugal
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia
Ongoing
2016/01/01 - Current Epigenetic in Chronic Lymphocytic Leukemia B - Impact in prognosis and therapy
Project FMUC-BST-2016-2020
Researcher
Banco Santander Totta, Portugal

Universidade de Coimbra Faculdade de Medicina, Portugal
Banco Santander Totta

Universidade de Coimbra Faculdade de Medicina
Ongoing
2012/01/01 - Current Characterization of Cellular and Molecular mechanisms involved in Sensitivity and Resistance to BCR-ABL targeted therapies in Chronic Myelogenous Leukemia
Project 18/12
Researcher
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia, Portugal
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia
Ongoing
2016/01/01 - 2018 The role of microRNAs for chronic myeloid leukemia therapeutic selection
Project FMUC-BST-2016-2014
Researcher
Banco Santander Totta, Portugal

Universidade de Coimbra Faculdade de Medicina, Portugal
Banco Santander Totta

Universidade de Coimbra Faculdade de Medicina
Ongoing
2014/01/01 - 2018 The role of MicroRNAs for therapeutic selection in BCR-ABL+ Leukemias
Project 10/14
Researcher
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia, Portugal
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia
Ongoing
2012/01/01 - 2014/12/31 Caracterização Clínica e Molecular da Síndrome Mielodisplásica - Implicações no Prognóstico e Terapêutica
Project 24/09
Researcher
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia, Portugal
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia
Concluded
Outputs

Publications

Book chapter
  1. Bergantim, Rui; Jorge, Joana; Peixoto da Silva, Sara; Alves, Raquel; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana Bela; Guimarães, José E.; Vasconcelos, M. Helena. "The Role of MicroRNAs in Mature B-Cell Neoplasias Drug Resistance". In Comprehensive Hematology and Stem Cell Research, 484-505. Elsevier, 2025.
    10.1016/b978-0-443-15717-2.00013-5
  2. Alves, R.; Jorge, Joana; Lapa, B.; Ribeiro, I.P.; Teles, P. ; Nobre Góis, I.; Santos, L.; et al. "Altered Cell Cycle Regulation in the Development of Resistance.". In Resistance in Hematologic Malignancies and Cancer. Elsevier, 2024.
    Published
  3. Alves, R.; Jorge, Joana; Costa, M.I.; Abrantes, A.M.; Botelho, M.F.; Gonçalves, A.C.; Sarmento-Ribeiro, A.B.. "Reduce drug uptake in development of resistance". In Resistance in Hematologic Malignancies and Cancer. Elsevier, 2024.
    Published
  4. "Aging-related neoplasia". In Aging: From Fundamental Biology to Societal Impact, edited by Oliveira, P.; Malva, J.. Elsevier, 2022.
    In press
  5. Sarmento-Ribeiro, A.B.; Gonçalves, A.C.; Afonso, C.; Alves, R.; Góis, I.; Jorge, Joana; Casalta, J.P.; et al. "Kinases Inhibitors in Cancer Therapy". In An Introduction to Cancer Therapy. Nova Science Publishers, 2020.
    Published
Conference abstract
  1. Alves, R.; Silva, I.; Costa, M.I.; Lapa, B.; Jorge, Joana; Gonçalves, A.C.; Sarmento-Ribeiro, A. B.. "Buparlisib a promising therapeutic approach in chronic myeloid leukemia resistant to imatinib". Paper presented in EHA2023 Hybrid Congress, 2023.
    Published
  2. Jorge, Joana; Constantino, B.; Santiago, H.; Costa, M.I.; Lapa, B.; Alves, R.; Gonçalves, A.C.; Sarmento-Ribeiro, A. B.. "Nrf2 inhibition in combination with ibrutinib in the treatment of chronic lymphocytic leukemia– An in vitro study". Paper presented in EHA2023 Hybrid Congress, 2023.
    Published
  3. Alves, R.; Almeida, A.S.; Costa, M.I.; Lapa, B.; Jorge, Joana; Gonçalves, A.C.; Geraldes, C.; Sarmento-Ribeiro, A. B.. "Molecular mechanisms of resistance to immunomodulators in multiple myeloma: An in vitro study.". Paper presented in EHA2023 Hybrid Congress, 2023.
    Published
  4. Lapa, B.; Portelinha, A.P.; Costa, M.I.; Jorge, Joana; Alves, R.; Sarmento-Ribeiro, A. B.; Gonçalves, A.C.. "Niraparib in B-cell lymphoid malignancies: Exploring synthetic lethality as target for therapy". Paper presented in EHA2023 Hybrid Congress, 2023.
    Published
  5. Lapa, B.; Costa, M.I.; Jorge, Joana; Alves, R.; Sarmento-Ribeiro, A. B.; Gonçalves, A.C.. "Inhibition of the DNA damage response: A possible new route in acute myeloblastic leukemia treatment.". Paper presented in EHA2023 Hybrid Congress, 2023.
    Published
  6. Jorge, Joana; Santiago, H.; Constantino, B.; Costa, M.I.; Lapa, B.; Alves, R.; Gonçalves, A.C.; Sarmento-Ribeiro, A. B.. "Telaglenastat (CB-839) in monotherapy and in combination with epigenetic modulators or ibrutinib induces cell death in chronic lymphocytic leukemia cells". Paper presented in EHA2023 Hybrid Congress, 2023.
    Published
  7. Lapa, B.; Costa, MI; Figueiredo, D.; Jorge, Joana; Alves, R.; Monteiro, AR; Silva, MR; et al. "The therapeutic potential of AZD-7648, a DNA-PK inhibitor, on acute myeloblastic leukemia". Paper presented in EACR 2023 Congress, Torino, 2023.
    Published
  8. Magalhães, M. ; Dominguez-Martín, E.M.; Jorge, Joana; Gonçalves, AC; Oliveira, P; Efferth, T.; Rijo, P.; Cabral, C.. "Unravelling an abietane diterpenoid with very promising chemotherapeutic potential against glioblastoma cells". Paper presented in 71st International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research, Dublin, 2023.
    Published
  9. Magalhães, M; Domínguez-Martín , EM; Jorge, Joana; Gonçalves, AC; Duarte, AI; Oliveira, P; Efferth, T; Rijo, P; Cabral, C. "Unraveling the chemotherapeutic potential of Royleanone, a natural drug lead, against glioblastoma". Paper presented in EACR 2023 Congress, Torino, 2023.
    Published
  10. Magalhães, M. ; Dominguez-Martín, E.M.; Jorge, J.; Gonçalves, A.C.; Díaz-Lanza, A.M.; Manadas, B.; Efferth, T.; Rijo, P.; Cabral, C.. "Parvifloron D-based therapy for glioblastoma: targeting tumor microenvironment with a natural drug lead". Paper presented in 56th ESCI Annual Scientific Meeting, 2022.
    Published
  11. Carda, J.P.; Gomes, R.; Jorge, Joana; Gonçalves, A.C.; Marques, B.; Alves, R.; Sarmento-Ribeiro, A. B.. "NRF2 modulators in chronic lymphocytic leukemia patients: a possible new therapeutic approach". Paper presented in EHA2022 Hybrid Congress, 2022.
    Published
  12. Jorge, Joana; Gaspar, T.; Costa, M.I.; Lapa, B.; Alves, R.; Gonçalves, A.C.; Sarmento-Ribeiro, A. B.. "Demethylating agents and histone deacetylase inhibitors as new therapeutic strategies in chronic lymphocytic leukemia.". Paper presented in EHA2022 Hybrid Congress, 2022.
    Published
  13. Costa, M.I.; Lapa, B.; Jorge, Joana; Alves, R.; Sarmento-Ribeiro, A. B.; Gonçalves, A.C.. "Zinc in the modulation of the antiproliferative and cytotoxic effects of Olaparib in acute myeloid leukemia". Paper presented in EHA2022 Hybrid Congress, 2022.
    Published
  14. Lapa, B.; Costa, M.I.; Jorge, Joana; Alves, R.; Sarmento-Ribeiro, A. B.; Gonçalves, A.C.. "Therapeutic potential of DNA damage response in acute myeloblastic leukemia". Paper presented in EHA2022 Hybrid Congress, 2022.
    Published
  15. Afonso, C.; Roque, D.; Alves, R.; Magalhães, N.; Costa, M.I.; Gomes, E.; Figueiredo, D.; et al. "Unravelling resistance mechanisms to proteasome inhibitors in multiple myeloma". Paper presented in EHA2021 Virtual Congress, 2021.
    Published
  16. Magalhães, N.; Figueiredo, D.; Alves, R.; Roque, D.; Costa, M.I.; Gomes, E.; Jorge, Joana; et al. "NRF2 as a therapeutic target in acute leucemia – In vitro studies with oltipraz". Paper presented in EHA2021 Virtual Congress, 2021.
    Published
  17. Gomes, E.; Jorge, Joana; Carda, J. P.; Costa, M.I.; Magalhães, N.; Roque, D.; Alves, R.; et al. "Relevance of NRF2/KEAP1 axis in chronic lymphocytic leukemia development". Paper presented in EHA2021 Virtual Congress, 2021.
    Published
  18. Costa, M.I.; Magalhães, N.; Roque, D.; Alves, R.; Jorge, Joana; Lapa, B.; Nascimento-Costa, J. M.; Sarmento-Ribeiro, A. B.; Gonçalves, A.C.. "Zinc in the modulation of the DNA damage response – Preventive, genotoxic and cytotoxic roles in acute myeloid leukemia". Paper presented in EHA2021 Virtual Congress, 2021.
    Published
  19. Costa, M.I.; Magalhães, N.; Roque, D.; Gomes, E.; Alves, R.; Jorge, Joana; Lapa, B.; et al. "Zinc as a genoprotective player of DNA damage response – Preliminary results". Paper presented in CIMAGO Meeting – Challenges in Oncobiology, 2020.
    Published
  20. Alves, R.; Gonçalves, A.C.; Jorge, Joana; Afonso, C.; Roque, A.; Paiva, A.; Ribeiro, L.; Geraldes, C.; Sarmento-Ribeiro, A.B.. "Relevance of NF-kB and NRF2 transcription factors into multiple myeloma pathophysiology – A preliminary study". Paper presented in CIMAGO Meeting, Coimbra, 2020.
    Published
  21. Jorge, Joana; Estevam, A.; Alves, R.; Lapa, B.; Nascimento-Costa, J.M.; Gonçalves, A.C.; Sarmento-Ribeiro, A.B.. "STAT5 – A new therapeutic target in acute lymphoblastic leukemia?". Paper presented in CIMAGO Meeting, Coimbra, 2020.
    Published
  22. Silva, D.; Gonçalves, A.C.; Marques, B.; Jorge, Joana; Alves, R.; Ribeiro, A. B.; Cortesão, E.; Nascimento-Costa, J.M.; Sarmento-Ribeiro, A.B.. "Aldehyde dehydrogenase polymorphisms: The role in myelodysplastic syndromes and acute myeloid leukemia". Paper presented in CIMAGO meeting, Coimbra, 2020.
    Published
  23. Gomes, R.; Gonçalves, A.C.; Jorge, Joana; Alves, R.; Pereira, A.; Sarmento-Ribeiro, A.B.; Nascimento-Costa, J. M.. "IREB2 rs17483548 single nucleotide polymorphism is associated with colorectal cancer". Paper presented in CIMAGO meeting, Coimbra, 2020.
    Published
  24. Figueiredo, D.; Jorge, Joana; Alves, R.; Lapa, B.; Gonçalves, A.C.; Sarmento-Ribeiro, A.B.. "NRF2 modulation as a new therapeutic approach in AML – In vitro studies". Paper presented in CIMAGO meeting, Coimbra, 2020.
    Published
  25. Carda, J.P.; Alves, R.; Jorge, Joana; Duarte, S.; Pereira, A.; Ribeiro, I.P.; Ribeiro, L.; et al. "Epigenetics in chronic lymphocytic leukemia - Role in pathogenesis and treatment". Paper presented in CIMAGO Meeting, Coimbra, 2020.
    Published
  26. Magalhães, N.; Roque, D.; Costa, M.I.; Gomes, E.; Jorge, Joana; Alves, R.; Lapa, B.; Gonçalves, A.C.; Sarmento-Ribeiro, A.B.. "Therapeutic effect of Oltipraz in acute lymphoblastic leukemia - Preliminary in vitro studies". Paper presented in CIMAGO meeting, Coimbra, 2020.
    Published
  27. Lapa, B.; Alves, R.; Jorge, Joana; Cortesão, E.; Pereira, A.; Ribeiro, L.; Gonçalves, A.C.; Sarmento-Ribeiro, A.B.. "EPO-EPOR axis as a prognostic and drug response biomarker in myelodysplastic syndrome - Preliminary results". Paper presented in CIMAGO meeting, Coimbra, 2020.
    Published
  28. Gonçalves, A.C.; Silva, D.; Marques, B.; Jorge, Joana; Alves, R.; Ribeiro, A.B.; Cortesão, E.; Nascimento-Costa, J.M.; Sarmento-Ribeiro, A.B.. "Aldehyde dehydrogenase genetic variants influence the risk myelodysplastic syndromes and acute myeloid leukemia development and progression". Paper presented in 25th Congress of the European Hematology Association, 2020.
    Published
  29. Alves, R.; Gonçalves, A.C.; Carda, J.P.; Jorge, Joana; Duarte, S.; Pereira, A.; Ribeiro, I.P.; et al. "Role of epigenetics inchronic lymphocytic leukemia pathogenesis and treatment". Paper presented in 25th Congress of the European Hematology Association, 2020.
    Published
  30. Jorge, Joana; Estevam, A.; Alves, R.; Lapa, B.; Nascimento-Costa, J.M.; Gonçalves, A.C.; Sarmento-Ribeiro, A.B.. "Therapeutic potential of pimozide in acute lymphoblastic leukemia cell lines". Paper presented in 25th Congress of the European Hematology Association, 2020.
    Published
  31. Figueiredo, D.; Jorge, Joana; Alves, R.; Lapa, B.; Gonçalves, A.C.; Sarmento-Ribeiro, A.B.. "Can NRF2 modulation be a novel therapeutic approach in acute myeloblastic leukemia?". Paper presented in 25th Congress of the European Hematology Association, 2020.
    Published
  32. Alves, Raquel; Gonçalves, Ana Cristina; Jorge, Joana; Marques, Gilberto; Ribeiro, André; Tenreiro, Rita; Coucelo, Margarida; et al. "Genetic variability of influx and efflux transporters: the impact on susceptibility to chronic myeloid leukemia development". Paper presented in 53rd Annual Scientific Meeting of the European Society for Clinical Investigation, Coim, 2019.
    Published • doi: 10.1111/eci.13109
  33. Andrade, Diana; Jorge, Joana; Alves, Raquel; Marini, Sandra; Carda, José Pedro; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana Bela. "DNA methyltransferases gene expression levels in chronic lymphocytic leucemia – Impact in development, diagnosis and prognosis.". Paper presented in 24th Congress of the European Hematology Association, Frankfurt, 2019.
    Published
  34. Lapa, Beatriz; Jorge, Joana; Alves, Raquel; Pires, Ana; Abrantes, Ana Margarida; Coucelo, Margarida; Abrunhosa, Antero; et al. "Glycolysis versus oxidative phosphorylation – Potential therapeutic targets in AML". Paper presented in 24th Congress of the European Hematology Association, Frankfurt, 2019.
    Published
  35. Alves, Raquel; Gonçalves, Ana Cristina; Jorge, Joana; Marques, Gilberto; Barbosa, André; Tenreiro, Rita; Coucelo, Margarida; et al. "Influx/efflux transportes in chronic myeloid leucemia: the influence of genetic variants on susceptibility and drug response". Paper presented in 24th Congress of the European Hematology Association, Frankfurt, 2019.
    Published
  36. Lima, João; Jorge, Joana; Alves, Raquel; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana Bela. "Therapeutic potential of gambogic acid and silibinin in acute myeloblastic leukemia – In vitro studies". Paper presented in 24th Congress of the European Hematology Association, Frankfurt, 2019.
    Published
  37. Nascimento, Telma; Adão, Diana; Oliveira, Alexandra; Pires, Luís Miguel; Alves, Raquel; Jorge, Joana; Ribeiro, Ilda P; et al. "Genomic characterization of chronic lymphocytic leucemia and multiple myeloma: role of array compararive genomic hybridization (ACGH)". Paper presented in 24th Congress of the European Hematology Association, Frankfurt, 2019.
    Published
  38. Jesus, N.; Jorge, Joana; Alves, R.; Gonçalves, AC; Sarmento-RIbeiro, AB. "Metformin and sirolimus as new treatment options in childhood acute lymphoblastic leukemia". Paper presented in 14th YES Meeting, Porto, 2019.
    Published
  39. Ferreira, Catarina; Jorge, Joana; Alves, Raquel; Goncalves, Ana Cristina; Sarmento-Ribeiro, Ana B.. "WNT/Beta-Catenina and Hedghog inhibithors as therapeutic approaches in B-cell neoplasms". Paper presented in European Hematology Association, 2018.
    Published
  40. Neves, Joana; Jorge, Joana; Alves, Raquel; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana B.. "Parthenolide, na NF-kB inhibitor, induce cell death and supress cell proliferation in lymphoid malignancies.". Paper presented in European Hematology Association, 2018.
    Published
  41. Ribau, Beatriz; Jorge, Joana; Alves, Raquel; Ribeiro, Ilda P; Marques Carreira, Isabel; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana B.. "Epigenetic modulators show in vitro therapeutic potential to treat B cell acute lymphoblastic leukemia". Paper presented in European Hematology Association, 2018.
    Published
  42. Jorge, Joana; Pires, Ana; Alves, Raquel; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana B.. "Notch pathway as a therapeutic target in acute lymphoblastic leukemia.". Paper presented in European Hematology Association, 2018.
    Published
  43. Alves, Raquel; Gonçalves, Ana Cristina; Jorge, Joana; Almeida, António M.; Sarmento-Ribeiro, Ana B.. "PGP and BCRP inhibitor as a modulator of Imatinib resistance". Paper presented in European Hematology Association, 2018.
    Published
  44. Santos, Diogo; Alves, Raquel; Gonçalves, Ana Cristina; Jorge, Joana; Girão, Henrique; Catarino, Steve; Barbosa de Melo, Joana; Sarmento-Ribeiro, Ana B.. "Heat shock protein 90 inhibition as a potential therapeutic target in chronic myeloid leukemia". Paper presented in European Hematology Association, 2018.
    Published
  45. Alves, Raquel; Gonçalves, Ana Cristina; Jorge, Joana; Luís, Dino; Ribeiro, André; Marques, G.; Jorge, L.; et al. "Imatinib response and microRNAs profile in CML- A biomarker for drug response.". Paper presented in European Hematology Association, 2018.
    Published
  46. Gonçalves, Ana Cristina; Macedo, Bárbara; Ribeiro, André; Alves, Raquel; Jorge, Joana; Marques, G.; Jorge, L.; Cortesao, Emília; Sarmento-Ribeiro, Ana B.. "Diagnostic potential of Aldehyde Dehydrogenases isoenzymes in MDS and AML.". Paper presented in European Hematology Association, 2018.
    Published
  47. Ferreira, Catarina; Jorge, Joana; Alves, Raquel; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana B.. "Conserved embryonic signaling pathways inhibitors as new therapeutic strategies in B-cell Neoplasms". Paper presented in CIMAGO Annual Scientific Meeting 2018, 2018.
    Published
  48. Ribau, Beatriz; Jorge, Joana; Alves, Raquel; Ribeiro, Ilda P; Marques Carreira, Isabel; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana B.. "Epigentic modulators in B-cell Acute Lymphoblastic Leukemia". Paper presented in CIMAGO Annual Scientific Meeting 2018, 2018.
    Published
  49. Neves, Joana; Jorge, Joana; Alves, Raquel; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana B.. "Parthenolide as a new therapeutic approach in Acute Lymphoblastic Leukemia". Paper presented in CIMAGO Annual Scientific Meeting 2018, 2018.
    Published
  50. Santos, Diogo; Alves, Raquel; Gonçalves, Ana Cristina; Jorge, Joana; Catarino, Steve; Girão, Henrique; Barbosa de Melo, Joana; Sarmento-Ribeiro, Ana B.. "The potential therapeutic effect of Heat Shock Protein 90 inhibition in Chronic Myeloid Leukemia". Paper presented in CIMAGO Annual Scientific Meeting 2018, 2018.
    Published
  51. Alves, Raquel; Gonçalves, Ana Cristina; Jorge, Joana; Luís, Dino; Ribeiro, André; Marques, G.; Jorge, L.; et al. "microRNAs profile in CML – A potential biomarker to Imatinib response.". Paper presented in CIMAGO Annual Scientific Meeting 2018, 2018.
    Published
  52. Alves, Raquel; Gonçalves, Ana Cristina; Jorge, Joana; Almeida, Antonio M.; Sarmento-Ribeiro, Ana B.. "Elacridar as a modulator of Imatinib resistance". Paper presented in CIMAGO Annual Scientific Meeting 2018, 2018.
    Published
  53. Gonçalves, Ana Cristina; Macedo, Bárbara; Alves, Raquel; Jorge, Joana; Ribeiro, André; Marques, G.; Jorge, L.; Cortesao, Emília; Sarmento-Ribeiro, Ana B.. "Aldehyde Dehydrogenases as potential biomarkers in Myeloid Neoplasias". Paper presented in CIMAGO Annual Scientific Meeting 2018, 2018.
    Published
  54. Jorge, Joana; Pires, A.; Alves, R.; Gonçalves, A.C.; Sarmento-Ribeiro, A. B.. "Can ¿-secretase inhibitors be a good therapeutic approach in Acute Lymphoblastic Leukemia?". 2018.
    Published
  55. Lapa, B.; Jorge, Joana; Alves, R.; Pires, A.S.; Abrantes, A.M.; Coucelo, M. ; Botelho, M.F.; Gonçalves, A.C.; Sarmento-Ribeiro, A. B.. "Metabolism as a therapeutic target in acute myeloid leukemic – glycolysis or oxidative phosphorylation?". 2018.
    Published
  56. Santos, D.; Alves, R.; Gonçalves, A.C.; Jorge, Joana; Girão, H.; Catarino, S.; Barbosa Melo, J.; Sarmento-Ribeiro, A. B.. "Alvespimycin is a promising drug in resistant Chronic Myeloid Leukemia". 2018.
    Published
  57. Macedo, Bárbara; Jorge, Joana; Alves, Raquel; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana B.. "ALDHs as potential biomarkers in myeloid neoplasms – Preliminary study.". Paper presented in YES Meeting 2017, 2017.
    Published • http://dx.doi.org/10.1016/j.pbj.2017.07.018
  58. Ribau, Beatriz; Jorge, Joana; Alves, Raquel; Ribeiro, Ilda P; Marques Carreira, Isabel; Sarmento-Ribeiro, Ana B.. "Epigenetic modifications as targets to new therapies for Chronic Lymphocytic leukaemia – A preliminary study". Paper presented in YES Meeting 2017, 2017.
    Published • http://dx.doi.org/10.1016/j.pbj.2017.07.112
  59. Ferreira, Catarina; Jorge, Joana; Alves, Raquel; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana B.. "WNT/beta-catenin and Hedgehog signaling pathways as therapeutic targets in B-cell neoplasms". Paper presented in YES Meeting 2017, 2017.
    Published • http://dx.doi.org/10.1016/j.pbj.2017.07.021
  60. Neves, Joana; Jorge, Joana; Alves, Raquel; Goncalves, Ana Cristina; Sarmento-Ribeiro, Ana B.. "Cytotoxic effects of parthenolide on lymphoid malignancies’ cell lines". Paper presented in YES Meeting 2017, 2017.
    Published • http://dx.doi.org/10.1016/j.pbj.2017.07.020
  61. Marini, S.; Carda, J.; Antunes, J.; Ribeiro, A.; Tenreiro, R.; Ruzickova, L.; Alves, R.; et al. "Role of KEAP1-NRF2 pathway genetic variability in the susceptibility and prognosis of patients with chronic lymphocytic leukemia". 2017.
    Published
  62. Pires, Ana; Jorge, Joana; Alves, Raquel; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana B.. "The embrionary signaling pathways as therapeutic targets in acute lymphoblastic leukemia". Paper presented in 5th CIMAGO Congress, 2016.
    Published
  63. Jorge, Joana; Gonçalves, Ana Cristina; Cortesao, Emília; Geraldes, Catarina; Pires, Ana; Fernandes, Sara; Alves, Raquel; Ribeiro, Letícia; Sarmento-Ribeiro, Ana B.. "NFE2L2 and KEAP1 gene expression analysis in hematological malignancies - Clinical implications". Paper presented in 5th CIMAGO congress, 2016.
    Published
  64. Jorge, J.; Goncalves, A. C.; Cortesao, E.; Geraldes, C.; Gomes, B.; Pires, A.; Fernandes, S.; et al. "NFE2L2, KEAP1 and NQO1 gene expression in myelodysplastic syndrome and monoclonal gammopathies - Clinical implications". 2016.
    Published
  65. Pires, A.; Jorge, J.; Alves, R.; Goncalves, A. C.; Sarmento-Ribeiro, A. B.. "THE TERAPEUTIC POTENTIAL OF EMBRIONARY SIGNALING PATHWAYS INHIBITION IN ACUTE LYMPHOBLASTIC LEUKEMIA". 2016.
    Published
  66. Gonçalves, Ana Cristina; Alves, Raquel; Pires, Ana; Jorge, Joana; Baldeiras, I.; Cortesao, Emília; Carda, José Pedro; et al. "THE INTERPLAY BETWEEN OXIDATIVE STRESS AND DNA METHYLATION – ROLE IN DEVELOPMENT, DIAGNOSIS AND PROGNOSIS OF MYELOID NEOPLASIAS". Paper presented in 4th CIMAGO Congress, 2015.
    Published
  67. Fernandes, Sara; Jorge, Joana; Gonçalves, Ana Cristina; Alves, Raquel; Pires, Ana; Veiga, Sara; Cortesao, Emília; et al. "INFLUENCE OF THE ABC TRANSPORTERS’ GENETIC PROFILES IN THE DEVELOPMENT OF MYELOID NEOPLASIAS". Paper presented in 4th CIMAGO Congress, 2015.
    Published
  68. Gonçalves, Ana Cristina; Alves, Raquel; Pires, Ana; Jorge, Joana; Mota-Vieira, Luisa; Nascimento Costa, Jose M.; Sarmento-Ribeiro, Ana B.. "CHRONIC EXPOSURE TO OXIDATIVE STRESS INDUCERS INFLUENCE METHYLATION STATUS IN NORMAL AND NEOPLASTIC HEMATOLOGICAL CELLS". Paper presented in 4th CIMAGO Congress, 2015.
    Published
  69. Fernandes, S. I.; Gonalves, A. C.; Jorge, J.; Geraldes, C.; Alves, R.; Pires, A.; Veiga, S.; et al. "INFLUENCE OF ABC TRANSPORTERS' GENETIC PROFILES IN THE DEVELOPMENT OF MONOCLONAL GAMMOPATHIES". 2015.
    Published
  70. Goncalves, A. C.; Alves, R.; Pires, A.; Jorge, J.; Mota-Vieira, L.; Nascimento-Costa, J. M.; Sarmento-Ribeiro, A. B.. "EXPOSURE TO ROS INDUCES DNA DAMAGE AND INFLUENCES DNA METHYLATION IN NORMAL AND MALIGNANT HEMATOLOGICAL CELL LINES". 2015.
    Published
  71. Jorge, Joana; Cortesao, Emília; Gonçalves, Ana Cristina; Pires, Ana; Alves, Raquel; Sousa, Isabel; Moucho, C.; et al. "Methylation pattern in Myelodysplastic Syndrome – Comparative study between bone marrow and peripheral blood". Paper presented in 3rd CIMAGO Congress, 2014.
    Published
  72. Cortesao, Emília; Jorge, Joana; Gonçalves, Ana Cristina; Pires, Ana; Alves, Raquel; Sousa, Isabel; Moucho, C.; et al. "Gene Methylation - The role in Myelodysplastic Syndrome". Paper presented in 3rd CIMAGO Congress, 2014.
    Published
  73. Pires, Ana; Jorge, Joana; Alves, Raquel; Domingues, C.; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana B.. "The Bone Marrow Microenvironment as a therapeutic target in Hematologic Neoplasias – The role of Matrix Metalloproteinases.". Paper presented in 3rd CIMAGO Congress, 2014.
    Published
  74. Domingues, C.; Ferreira, Mariana; Pires, C. ; Matias, C.; Lourenço, T.; Pires, Ana; Jorge, Joana; et al. "The role of Vismodegib (GDC-0449) in Hematological Neoplasias Treatment". Paper presented in 3rd CIMAGO Congress, 2014.
    Published
  75. Pires, A.; Alves, R.; Jorge, J.; Balca-Silva, J.; Domingues, C.; Goncalves, A. C.; Sarmento-Ribeiro, A. B.. "BATIMASTAT, A MATRIX METALLOPROTEINASE INHIBITOR, AS A THERAPEUTIC APROACH IN HEMATOLOGIC NEOPLASIAS". 2014.
    Published
  76. Jorge, J. M.; Cortesao, E.; Goncalves, A. C.; Pires, A.; Alves, R.; Moucho, C.; Rito, L.; et al. "GENE METHYLATION IN MYELODYSPLASTIC SYNDROME - A COMPARATIVE STUDY BETWEEN BONE MARROW AND PERIPHERAL BLOOD". 2014.
    Published • 10.1093/annonc/mdu339.32
  77. Cortesao, E.; Jorge, J.; Goncalves, A. C.; Pires, A.; Alves, R.; Mocho, C.; Rito, L.; et al. "DAPK AND TRAIL RECEPTORS METHYLATION STATUS IN MYELODYSPLASTIC SYNDROMES PATIENTS". 2014.
    Published
Conference poster
  1. Marto, C.M.; Laranjo, M.; Gonçalves, A.C.; Paula, A.; Jorge, Joana; Sarmento-Ribeiro, A.B.; Marques-Ferreira, M.; et al. "In vitro characterization of dedifferentiated gingival fibro-blasts.". Paper presented in IV Metabolism, Ageing & Disease (MAD) Meeting, 2024.
  2. Alves, R.; Gomes, R.; Furtado, S.; Jorge, Joana; Lapa, B.; Costa, MI; Gonçalves, AC; Sarmento-Ribeiro, AB. "Telaglenastat, a glutaminase inhibithor, as a potential therapeutic target in chronic myeloid leukemia: An in vitro study". Paper presented in CIMAGO Congress, 2024.
  3. Costa, MI; Lapa, B.; Jorge, Joana; Alves, R.; Sarmento-Ribeiro, AB; Gonçalves, AC. "Zinc in the modulation of the DNA damage response: Preventive, genotoxic, and cytotoxic roles in acute myeloid leukemia.". Paper presented in CIMAGO Congress, 2024.
  4. Alves, R.; Ventura, F.; Jorge, Joana; Marques, G.; Coucelo, M. ; Freitas-Tavares, P.; Almeida, A.; Gonçalves, A.C.; Sarmento-Ribeiro, A.B.. "Influência das variantes genéticas de genes relacionados com o stresse oxidativo no prognóstico e resposta à terapêutica na leucemia mielóide crónica". Paper presented in Reunião Anual da Sociedade de Portuguesa de Hematologia, 2023.
  5. Jorge, Joana; Gonçalves, A.C.; Berral-Gonzalez, A.; Alves, R.; De Las Rivas, J.; Sarmento-Ribeiro, A.B.. "Tumor educated platelets signature allow to identify and predict the survival of multiple myeloma patients.". Paper presented in III ASPIC-ASEICA International Meeting – Cancer Immunology, Tumor Microenvironment and Metastasis, 2023.
  6. Costa, M.I.; Lapa, B.; Jorge, Joana; Alves, R.; Sarmento-Ribeiro, A.B.; Gonçalves, A.C.. "Zinc in the modulation of the DNA damage response: preventive, genotoxic, and cytotoxic roles in acute myeloid leucemia.". Paper presented in III ASPIC-ASEICA International Meeting – Cancer Immunology, Tumor Microenvironment and Metastasis, 2023.
  7. Lapa, B.; Costa, M.I.; Jorge, Joana; Alves, R.; Sarmento-Ribeiro, A.B.; Gonçalves, A.C.. "Modulation of PARP1/2 and CHK1 as a novel treatment for acute myeloid leukemia - in vitro study". Paper presented in III ASPIC-ASEICA International Meeting – Cancer Immunology, Tumor Microenvironment and Metastasis, 2023.
  8. Alves, R.; Almeida, A.S.; Costa, M.I.; Lapa, B.; Jorge, Joana; Gonçalves, A.C.; Geraldes, C.; Sarmento-Ribeiro, A.B.. "Molecular mechanisms of resistance to immunomodulators in multiple myeloma: An in vitro study". Paper presented in European Association of Hematology Hybrid Congress, 2023.
  9. Alves, R.; Silva, I.; Costa, M.I.; Lapa, B.; Jorge, Joana; Gonçalves, A.C.; Sarmento-Ribeiro, A.B.. "Buparlisib a promising therapeutic approach in chronic myeloid leukemia resistant to imatinib". Paper presented in European Association of Hematology Hybrid Congress, 2023.
  10. Lopes, M.R.; Jorge, Joana; Alves, R.; Geraldes, C.; Gonçalves, A.C.; Sarmento-Ribeiro, A.B.. "Inibição do NRF2 como nova abordagem terapêutica em neoplasias linfóides sensíveis e resistentes ao bortezomib – Estudo preliminar". Paper presented in 31ª Sabatina de Hematologia, 2023.
  11. Jorge, Joana; Oliveira, I.; Alves, R.; Lapa, B.; Costa, M.I.; Gonçalves, A.C.; Geraldes, C.; Sarmento-Ribeiro, A.B.. "Modulação do NF-kB em modelos de mieloma múltiplo resistentes a inibidores de proteassoma.". Paper presented in 31ª Sabatina de Hematologia, 2023.
  12. Ventura, F.; Alves, R.; Jorge, Joana; Marques, G.; Coucelo, M. ; Diamond, J. ; Freitas-Tavares, P.; et al. "Influência das variantes genéticas do NFE2L2 na resposta à terapêutica na leucemia mielóide crónica". Paper presented in 31ª Sabatina de Hematologia, 2023.
  13. Costa, M.I.; Lapa, B.; Jorge, Joana; Alves, R.; Sarmento-Ribeiro, A.B.; Gonçalves, A.C.. "Efeito preventivo, genotóxicos e citotóxico na leucemia mieloblástica aguda". Paper presented in 31ª Sabatina de Hematologia, 2023.
  14. Lapa, B.; Costa, M.I.; Figueiredo, D.; Jorge, Joana; Alves, R.; Monteiro, A.R.; Reis Silva, M.; et al. "O potencial terapêutico do AZD-7648, um inibidor da DNA-PK, na leucemia mieloblástica aguda – Um estudo in vitro.". Paper presented in 31ª Sabatina de Hematologia, 2023.
  15. Costa, MI; Lapa, B.; Alves, R.; Jorge, Joana; Sarmento-RIbeiro, AB; Gonçalves, AC. "O potencial terapêutico do zinco na leucemia mieloblástica aguda: efeito citotóxico, citostático e genotóxico". Paper presented in 5th Encontro Nacional de Jovens Investigadores em Oncologia, 2023.
  16. Lapa, B.; Costa, MI; Figueiredo, D.; Jorge, Joana; Alves, R.; Monteiro, AR; Sarmento-RIbeiro, AB; Gonçalves, AC. "Modulação da DNA-PK no tratamento da leucemia mieloblástica aguda - um estudo in vitro". Paper presented in 5th Encontro Nacional de Jovens Investigadores em Oncologia, 2023.
  17. Lapa, B; Costa, MI; Figueiredo, D.; Jorge, Joana; Alves, R.; Monteiro, AR; Silva, MR; et al. "The therapeutic potential of AZD-7648, a DNA-PK inhibitor, on acute myeloblastic leukemia". Paper presented in EACR 2023 Congress, 2023.
  18. Gomes, R.; Jorge, Joana; Lapa, B.; Costa, MI; Gonçalves, AC; Sarmento-RIbeiro, AB. "Inibição da glutaminólise com telaglenastat na leucemia mieloide crónica resistente ao imatinib: Estudo in vitro". Paper presented in 31ª Sabatina de Hematologia, 2023.
  19. Magalhães, M.; Dominguez-Martín, E.M.; Jorge, Joana; Gonçalves, AC; Oliveira, P.; Efferth, T.; Rijo, P.; Cabral, C.. "Unravelling an abietane diterpenoid with very promising chemotherapeutic potential against glioblastoma cells". Paper presented in 71st International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research, 2023.
  20. Magalhães, M; Domínguez-Martín, EM; Jorge, Joana; Gonçalves, AC; Duarte, AI; Oliveira, P; Efferth, T; Rijo, P; Cabral, C. "Unraveling the chemotherapeutic potential of Royleanone, a natural drug lead, against glioblastoma". Paper presented in EACR 2023 Congress., 2023.
  21. Constantino, B.; Alves, R.; Santiago, H.; Costa, M.I.; Lapa, B.; Jorge, Joana; Carda, J.P.; Gonçalves, A.C.; Sarmento-Ribeiro, A.B.. "Potencial terapêutico de inibidores de NRF2 na leucemia linfocítica crónica em associação com o ibrutinib: Estudos in vitro". Paper presented in Reunião Anual da Sociedade de Portuguesa de Hematologia, 2022.
  22. Silva, I.; Jorge, Joana; Costa, M.I.; Lapa, B.; Alves, R.; Gonçalves, A.C.; Sarmento-Ribeiro, A.B.. "Potencial terapêutico do buparlisib na leucemia mielóide crónica e resistente ao imatinib – Estudo preliminar". Paper presented in Reunião Anual da Sociedade de Portuguesa de Hematologia, 2022.
  23. Lapa, B.; Costa, M.I.; Jorge, Joana; Alves, R.; Sarmento-Ribeiro, A.B.; Gonçalves, A.C.. "Potencial terapêutico de moduladores dos sistemas de reparação do DNA na leucemia mieloblástica aguda – Estudo preliminar in vitro". Paper presented in Reunião Anual da Sociedade de Portuguesa de Hematologia, 2022.
  24. Figueiredo, D.; Costa, M.I.; Lapa, B.; Jorge, Joana; Alves, R.; Sarmento-Ribeiro, A.B.; Gonçalves, A.C.. "Caracterização dos sistemas de reparação do DNA na leucemia mieloblástica aguda – Estudo preliminar in vitro.". Paper presented in Reunião Anual da Sociedade de Portuguesa de Hematologia, 2022.
  25. Portelinha, A.P.; Costa, M.I.; Lapa, B.; Jorge, Joana; Alves, R.; Sarmento-Ribeiro, A.B.; Gonçalves, A.C.. "Potencial terapêutico do niraparib em neoplasias linfóides – Estudos in vitro". Paper presented in Reunião Anual da Sociedade de Portuguesa de Hematologia, 2022.
  26. Jorge, Joana; Santos, D.; Alves, R.; Gonçalves, A.C.; Girão, H.; Catarino, S.; Melo, J.; Sarmento-Ribeiro, A.B.. "Therapeutic inhibition of Heat sock protein 90 in chronic myeloid leukemia - A new therapeutic approach to circumvent imatinib resistance". Paper presented in STRATAGEM - Annual Conference, 2022.
  27. Lapa, B.; Costa, M.I.; Jorge, Joana; Alves, R.; Sarmento-Ribeiro, A.B.. "Modulation of DNA damage repair in the treatment of acute myeloblastic leukemia in vitro study.". Paper presented in STRATAGEM - Annual Conference, 2022.
  28. Figueiredo, D.; Costa, M.I.; Lapa, B.; Jorge, Joana; Alves, R.; Sarmento-Ribeiro, A.B.; Gonçalves, A.C.. "Characterization of DNA Repair Systems in Acute Myeloblastic Leukemia.". Paper presented in STRATAGEM - Annual Conference, 2022.
  29. Santiago, H.; Constantino, B.; Costa, M.I.; Lapa, B.; Jorge, Joana; Alves, R.; Gonçalves, A.C.; Sarmento-Ribeiro, A.B.. "Glutaminolysis inhibition in monotherapy and in combination with epigenetic modulators and ibrutinib on a chronic lymphocytic leukemia cell model – Preliminary results". Paper presented in STRATAGEM - Annual Conference, 2022.
  30. Silva, I.; Portelinha, A.P.; Almeida, A.S.; Constantino, B.; Figueiredo, D.; Santiago, H.; Jorge, Joana; et al. "Therapeutic potential of Buparlisib in Chronic Myeloid Leukemia - Preliminary results". Paper presented in STRATAGEM - Annual Conference, 2022.
  31. Portelinha, A.P.; Almeida, A.S.; Constantino, B.; Figueiredo, D.; Santiago, H.; Silva, I.; Costa, M.I.; et al. "The therapeutic potential of niraparib in lymphoid malignancies". Paper presented in STRATAGEM - Annual Conference, 2022.
  32. Santiago, H.; Constantino, B.; Costa, M.I.; Lapa, B.; Jorge, Joana; Alves, R.; Gonçalves, A.C.; Sarmento-Ribeiro, A.B.. "O impacto da inibição da glutaminólise em monoterapia e em combinação com modularadores epigenéticos na leucemia linfocítica crónica – Resultados preliminares". Paper presented in 30ª Sabatina de Hematologia, 2022.
  33. Constantino, B.; Santiago, H.; Costa, M.I.; Lapa, B.; Jorge, Joana; Alves, R.; Gonçalves, A.C.; Sarmento-Ribeiro, A.B.. "Potencial terapêutico da inibição do NRF2 na leucemia linfocítica crónica em associação com ibrutinib – Estudos preliminares in vitro". Paper presented in 30ª Sabatina de Hematologia, 2022.
  34. Constantino, B.; Santiago, H.; Costa, M.I.; Lapa, B.; Jorge, Joana; Alves, R.; Gonçalves, A.C.; Carda, J.P.; Sarmento-Ribeiro, A.B.. "Therapeutic potential of the NRF2 inhibition in chronic lymphocytic leukemia with association with ibrutinib – Studies in vitro". Paper presented in STRATAGEM - Annual Conference, 2022.
  35. Oliveira, I.; Jorge, Joana; Lapa, B.; Costa, M.I.; Gonçalves, A.C.; Sarmento-Ribeiro, A.B.. "Partenolide: Potencial terapêutico em Mieloma Múltiplo resistente a inibidores de proteasoma.". Paper presented in Reunião Anual da Sociedade de Portuguesa de Hematologia, 2021.
  36. Costa, M.I.; Lapa, B.; Alves, R.; Jorge, Joana; Sarmento-Ribeiro, A.B.; Gonçalves, A.C.. "O zinco na modulação dos efeitos antiproliferativos e citotóxicos da citarabina e olaparib na leucemia mieloide aguda". Paper presented in Encontro Nacional de Jovens Investigadores em Oncologia, 2021.
  37. Gaspar, T.; Oliveira, I.; Luís, M.; Costa, M.I.; Jorge, Joana; Lapa, B.; Alves, R.; Gonçalves, A.C.; Sarmento-Ribeiro, A.B.. "Potencial terapêutico de moduladores epigenéticos na leucemia linfocítica cronica". Paper presented in Encontro Nacional de Jovens Investigadores em Oncologia, 2021.
  38. Oliveira, I.; Gaspar, T.; Luís, M.; Farinha, D. ; Alves, R.; Jorge, Joana; Lapa, B.; et al. "Partenolide: potencial terapêutico em mieloma múltiplo resistente a inibidores de proteasoma.". Paper presented in Encontro Nacional de Jovens Investigadores em Oncologia, 2021.
  39. Gomes, E.; Jorge, Joana; Carda, J. P.; Costa, M.I.; Magalhães, N.; Roque, D.; Alves, R.; et al. "Relevance of NRF2/KEAP1 axis in chronic lymphocytic leukemia development". Paper presented in European Hematology Association Virtual Congress, 2021.
  40. Costa, M.I.; Magalhães, N.; Roque, D.; Gomes, E.; Alves, R.; Jorge, Joana; Lapa, B.; et al. "Zinc in the modulation of the DNA damage response – Preventive, genotoxic and cytotoxic roles in acute myeloid leukemia.". Paper presented in European Association of Hematology Virtual Congress, 2021.
  41. Alves, R.; Gonçalves, A.C.; Jorge, Joana; Freitas-Tavares, p.; Pereira, A.; Nascimento-Costa, J.M.; Almeida, A.; Sarmento-Ribeiro, A.B.. "Everolimus - a mTOR inhibitor as a new drug for CML treatment". Paper presented in International Online Symposium on “New Therapeutic Tools Against Preclinical Models of Multidrug Resistant Tumors”, 2020.
  42. Gomes, E.; Costa, M.I.; Magalhães, N.; Roque, D.; Alves, R.; Jorge, Joana; Lapa, B.; et al. "O papel do eixo NRF2/KEAP1 no desenvolvimento da leucemia linfocítica crónica". Paper presented in Reunião Anual da Sociedade Portuguesa de Hematologia, 2020.
  43. Costa, M.I.; Magalhães, N.; Roque, D.; Gomes, E.; Alves, R.; Jorge, Joana; Lapa, B.; Nascimento-Costa, J.M.; Sarmento-Ribeiro, A.B.. "O zinco na modulação da reparação da lesão do DNA - Papel preventivo, genotóxico e citotóxico na leucemia mieloblástica aguda". Paper presented in Reunião Anual da Sociedade Portuguesa de Hematologia, 2020.
  44. Magalhães, N.; Figueiredo, D.; Roque, D.; Costa, M.I.; Gomes, E.; Jorge, Joana; Lapa, B.; et al. "O efeito do oltipraz no tratamento de leucemias agudas - Estudos in vitro". Paper presented in Reunião Anual da Sociedade Portuguesa de Hematologia, 2020.
  45. Costa, M.I.; Magalhães, N.; Roque, D.; Gomes, E.; Alves, R.; Jorge, Joana; Lapa, B.; Sarmento-Ribeiro, A.B.; Gonçalves, A.C.. "O duplo papel do zinco na modulação da resposta à lesão no DNA o contexto preventivo e tumoral". Paper presented in 2º Encontro nacional de Jovens Investigadores em Oncologia, 2020.
  46. Gomes, E.; Costa, M.I.; Magalhães, N.; Roque, D.; Alves, R.; Jorge, Joana; Lapa, B.; et al. "O stress oxidativo na leucemia linfocítica crónica: O papel do eixo NRF2/KEAP1 no desenvolvimento da doença". Paper presented in 2º Encontro nacional de Jovens Investigadores em Oncologia, 2020.
  47. Figueiredo, D.; Jorge, Joana; Alves, R.; Lapa, B.; Gonçalves, A.C.; Sarmento-Ribeiro, A.B.. "Modulação de NRF2 como nova abordagem terapêutica em LMA - Estudos In vitro". Paper presented in 2º Encontro nacional de Jovens Investigadores em Oncologia, 2020.
  48. Lapa, B.; Alves, R.; Jorge, Joana; Cortesão, E.; Ribeiro, A.B.; Pereira, A.; Ribeiro, L.; Gonçalves, A.C.; Sarmento-Ribeiro, A.B.. "O eixo EPO-EPOR como biomarcador de prognóstico e resposta ao tratamento na sindrome mielodisplásica - Resultados preliminares". Paper presented in 2º Encontro nacional de Jovens Investigadores em Oncologia, 2020.
  49. Magalhães, N.; Roque, D.; Costa, M.I.; Figueiredo, D.; Gomes, E.; Jorge, Joana; Lapa, B.; et al. "O efeito terapêutico do Oltipraz e do Brusatol na leucemia linfoblástica aguda". Paper presented in 2º Encontro nacional de Jovens Investigadores em Oncologia, 2020.
  50. Lapa, B.; Alves, R.; Jorge, Joana; Cortesão, E.; Ribeiro, A.B.; Pereira, A.; Ribeiro, L.; Gonçalves, A.C.; Sarmento-Ribeiro, A.B.. "O eixo EPO-EPOR como biomarcador de resposta ao tratamento com agentes estimuladores da eritropoiese na sindrome mielodisplásica - Resultados preliminares". Paper presented in Reunião Anual da Sociedade Portuguesa de Hematologia, 2020.
  51. Gonçalves, A.C.; Silva, D.; Marques, B.; Jorge, Joana; Alves, R.; Ribeiro, A.B.; Cortesão, E.; Nascimento-Costa, J.M.; Sarmento-Ribeiro, A.B.. "Aldehyde dehydrogenase genetic variants influence the risk myelodysplastic syndromes and acute myeloblastic leukemia development and treatment". Paper presented in 25th Congress of the European Hematology Association, 2020.
  52. Alves, R.; Gonçalves, A.C.; Carda, J.P.; Jorge, Joana; Duarte, S.; Pereira, A.; Ribeiro, I.P.; et al. "Role of epigenetics in chronic lymphocytic leukemia pathogenesis and treatment". Paper presented in 25th Congress of the European Hematology Association, 2020.
  53. Alves, R.; Gonçalves, A.C.; Jorge, Joana; Afonco, C.; Roque, A.; Paiva, A.; Ribeiro, L.; Geraldes, C.; Sarmento-Ribeiro, A.B.. "Relevance of NF-kB and NRF2 transcription factors into multiple myeloma pathophysiology - A preliminary study". Paper presented in CIMAGO Meeting – Challenges in Oncobiology, 2020.
  54. Jorge, Joana; Estevam, A.; Alves, R.; Lapa, B.; Nascimento-Costa, J.M.; Sarmento-Ribeiro, A.B.. "STAT5 - A new therapeutic target in acute lymphoblastic leukemia?". Paper presented in CIMAGO Meeting – Challenges in Oncobiology, 2020.
  55. Silva, D.; Gonçalves, A.C.; Marques, B.; Jorge, Joana; Alves, R.; Ribeiro, A.B.; Cortesão, E.; Nascimento-Costa, J. M.; Sarmento-Ribeiro, A. B.. "Aldehyde dehydrogenase polymorphisms: The role in myelodysplastic syndromes and acute myeloid leucemia". Paper presented in CIMAGO Meeting – Challenges in Oncobiology, 2020.
  56. Gomes, R.; Gonçalves, A.C.; Jorge, Joana; Alves, R.; Pereira, A.; Sarmento-Ribeiro, A.B.; Nascimento-Costa, J.M.. "IREB2 rs17483548 single nucleotide polymorphism is associated with colorectal cancer". Paper presented in CIMAGO Meeting – Challenges in Oncobiology, 2020.
  57. Figueiredo, D.; Jorge, Joana; Alves, R.; Lapa, B.; Gonçalves, A.C.; Sarmento-Ribeiro, A.B.. "NRF2 modulation as a new therapeutic approach in AML - In vitro studies". Paper presented in CIMAGO Meeting – Challenges in Oncobiology, 2020.
  58. Carda, J.P.; Alves, R.; Jorge, Joana; Duarte, S.; Pereira, A.; Ribeiro, I.P.; Gonçalves, A.C.; Carreira, I.M.; Sarmento-Ribeiro, A.B.. "Epigenetics in chronic lymphocytic leukemia - Role in pathogenesis and treatment". Paper presented in CIMAGO Meeting – Challenges in Oncobiology, 2020.
  59. Magalhães, N.; Roque, D.; Costa, M.I.; Gomes, E.; Jorge, Joana; Alves, R.; Lapa, B.; Gonçalves, A.C.; Sarmento-Ribeiro, A.B.. "Therapeutic effect of Oltipraz in acute lymphoblastic leukemia - Preliminary in vitro studies". Paper presented in CIMAGO Meeting – Challenges in Oncobiology, 2020.
  60. Costa, M.I.; Magalhães, N.; Roque, D.; Gomes, E.; Alves, R.; Jorge, Joana; Lapa, B.; et al. "Zinc as a genoprotective player of DNA damage response - Preliminary results". Paper presented in CIMAGO Meeting – Challenges in Oncobiology, 2020.
  61. Lapa, B.; Alves, R.; Jorge, Joana; Cortesão, E.; Pereira, A.; Ribeiro, L.; Gonçalves, A.C.; Sarmento-Ribeiro, A.B.. "EPO-EPOR axis as a prognostic and drug response biomarker in myelodysplastic syndrome – Preliminary results". Paper presented in CIMAGO meeting, 2020.
  62. Gonçalves, Ana Cristina; Alves, Raquel; Jorge, Joana; Ribeiro, André B.; Marques, Gilberto; Cortesão, Emília; Sarmento-Ribeiro, Ana Bela. "Aldeído desidrogenases: Potenciais biomarcadores em neoplasias mieloides". Paper presented in Reunião Anual da Sociedade Portuguesa de Hematologia, 2019.
  63. Gonçalves, Ana Cristina; Oliveira, Alexandra; Pires, Luís Miguel; Alves, Raquel; Jorge, Joana; Ribeiro, Ilda P; Roque, Adriana; et al. "Caracterização genómica do Mieloma Múltiplo por Array Comparative Genomic Hybridization (ACGH) - Resultados preliminares". Paper presented in Reunião Anual da Sociedade Portuguesa de Hematologia, 2019.
  64. Andrade, Diana; Jorge, Joana; Alves, Raquel; Marini, Sandra; Carda, José Pedro; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana Bela. "DNA metiltransferases na Leucemia Linfocítica cronica - Impacto no desenvolvimento, diagnóstico e prognóstico". Paper presented in Reunião Anual da Sociedade Portuguesa de Hematologia, 2019.
  65. Andrade, Diana; Jorge, Joana; Alves, Raquel; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana B.. "DNA methylatransferases gene expression levels in Chronic lymphocytic leukemia: the impact in development, diagnosis and prognosis". Paper presented in In4Med, 2019.
  66. Gomes, Rui; Jorge, Joana; Alves, Joana; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana B.; Nascimento Costa, José M.. "IREB2 gene expression in cancer - a pilot study". Paper presented in In4Med, 2019.
  67. Silva, Duarte; Jorge, Joana; Alves, Raquel; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana B.. "Aldehyde dehydrogenases polymorphisms: the role in myelodysplastic syndrome and acute myeloid leukemia". Paper presented in In4Med, 2019.
  68. Marques, Bárbara; Silva, Duarte; Jorge, Joana; Alves, Raquel; Luís, Dino; Ribeiro, André; Duarte, Sara; et al. "Aldehyde dehydrogenases polymorphisms: Their role in myelodysplastic syndromes". Paper presented in Diagnostic Masterclass Novartis, 2019.
  69. Pais, Ana Sofia; Reis, M; Laranjo, Mafalda; Reis, S; Jorge, Joana; Gonçalves, Ana Cristina; Sousa, AP; et al. "Estimulação in vitro da angiogénese de tecido ovárico criopreservado". Paper presented in 7º Congresso Português de Medicina da Reprodução, 2019.
  70. Nascimento, Telma; Adão, Diana; Oliveira, Alexandra; Pires, Luís Miguel; Alves, Raquel; Jorge, Joana; Ribeiro, Ilda P; et al. "Genomic characterization of chronic lymphocytic leucemia and multiple myeloma: role of array compararive genomic hybridization (ACGH).". Paper presented in 24th Congress of the European Hematology Association, 2019.
  71. Lima, João; Jorge, Joana; Alves, Raquel; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana Bela. "Therapeutic potential of gambogic acid and silibinin in acute myeloblastic leukemia – In vitro studies". Paper presented in 24th Congress of the European Hematology Association, 2019.
  72. Alves, Raquel; Gonçalves, Ana Cristina; Jorge, Joana; Marques, Gilberto; Barbosa, André; Tenreiro, Rita; Coucelo, Margarida; et al. "Influx/efflux transportes in chronic myeloid leucemia: the influence of genetic variants on susceptibility and drug response". Paper presented in 24th Congress of the European Hematology Association, 2019.
  73. Lapa, Beatriz; Jorge, Joana; Alves, Raquel; Pires, Ana Salomé; Abrantes, Ana Margarida; Coucelo, Margarida; Abrunhosa, Antero; et al. "Glycolysis versus oxidative phosphorylation – Potential therapeutic targets in AML". Paper presented in 24th Congress of the European Hematology Association, 2019.
  74. Andrade, Diana; Jorge, Joana; Alves, Raquel; Marini, Sandra; Carda, José Pedro; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana Bela. "DNA methyltransferases gene expression levels in chronic lymphocytic leucemia – Impact in development, diagnosis and prognosis". Paper presented in 24th Congress of the European Hematology Association, 2019.
  75. Alves, Raquel; Gonçalves, Ana Cristina; Jorge, Joana; Marques, Gilberto; Ribeiro, André; Tenreiro, Rita; Coucelo, Margarida; et al. "Genetic variability of influx and efflux transporters: the impact on susceptibility to chronic myeloid leukemia development". Paper presented in 53rd Annual Scientific Meeting of the European Society for Clinical Investigation, 2019.
  76. Lapa, Beatriz; Jorge, Joana; Alves, Raquel; Pires, Ana Salomé; Abrantes, Ana Margarida; Coucelo, Margarida; Abrunhosa, Antero; et al. "Potenciais alvos terapêuticos na leucemia mieloblástica aguda – glicólise ou oxidação fosforilativa?". Paper presented in 1º Encontro Nacional de Jovens Investigadores em Oncologia, 2019.
  77. Jesus, Nuno; Jorge, Joana; Alves, Raquel; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana Bela. "Metformin and Sirolimus as new treatment options in childhood acute lymphoblastic leukemia". Paper presented in 14th YESMeeting, 2019.
  78. Lima, João; Jorge, Joana; Alves, Raquel; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana B.. "Potencial terapêutico do Ácido Gambógico e da Silibinina na leucemia Mieloblástica aguda – Estudos in vitro". Paper presented in Reunião Anual da Sociedade Portuguesa de Hematologia, 2018.
  79. Nascimento, Telma; Adão, Diana; Pires, Luís Miguel; Alves, Raquel; Jorge, Joana; Ribeiro, Ilda P; Duarte, Sara; et al. "Caracterização genómica da leucemia linfocítica crónica por array Comparative Genomic Hybridization (aCGH) – Resultados preliminares". Paper presented in Reunião Anual da Sociedade Portuguesa de Hematologia, 2018.
  80. Santos, Diogo; Alves, Raquel; Gonçalves, Ana Cristina; Jorge, Joana; Girão, Henrique; Catarino, Steve; Barbosa de Melo, Joana; Sarmento-Ribeiro, Ana B.. "Alvespimycin is a promising drug in resistant Chronic Myeloid Leukemia". Paper presented in 13º YES Meeting, 2018.
  81. Lapa, Beatriz; Jorge, Joana; Alves, Raquel; Pires, Ana Salomé; Abrantes, Ana Margarida; Coucelo, Margarida; Botelho, Maria Filomena; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana B.. "Metabolism as a therapeutic target in acute myeloid leukemic – glycolysis or oxidative phosphorylation?". Paper presented in 13º YES Meeting, 2018.
  82. Jorge, Joana; Pires, Ana; Alves, Raquel; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana B.. "Can ¿-secretase inhibitors be a good therapeutic approach in Acute Lymphoblastic Leukemia?". Paper presented in CIMAGO Annual Scientific Meeting 2018, 2018.
  83. Ferreira, Catarina; Jorge, Joana; Alves, Raquel; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana B.. "Conserved embryonic signaling pathways inhibitors as new therapeutic strategies in B-cell Neoplasms". Paper presented in CIMAGO Annual Scientific Meeting 2018, 2018.
  84. Ribau, Beatriz; Jorge, Joana; Alves, Raquel; Ribeiro, Ilda P; Marques Carreira, Isabel; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana B.. "Epigentic modulators in B-cell Acute Lymphoblastic Leukemia". Paper presented in CIMAGO Annual Scientific Meeting 2018, 2018.
  85. Neves, Joana; Jorge, Joana; Alves, Raquel; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana B.. "Parthenolide as a new therapeutic approach in Acute Lymphoblastic Leukemia". Paper presented in CIMAGO Annual Scientific Meeting 2018, 2018.
  86. Santos, Diogo; Alves, Raquel; Gonçalves, Ana Cristina; Jorge, Joana; Catarino, Steve; Girão, Henrique; Barbosa de Melo, Joana; Sarmento-Ribeiro, Ana B.. "The potential therapeutic effect of Heat Shock Protein 90 inhibition in Chronic Myeloid Leukemia". Paper presented in CIMAGO Annual Scientific Meeting 2018, 2018.
  87. Alves, Raquel; Gonçalves, Ana Cristina; Jorge, Joana; Luís, Dino; Ribeiro, André; Marques, G.; Jorge, L.; et al. "microRNAs profile in CML – A potential biomarker to Imatinib response". Paper presented in CIMAGO Annual Scientific Meeting 2018, 2018.
  88. Alves, Raquel; Gonçalves, Ana Cristina; Jorge, Joana; Almeida, António M.; Sarmento-Ribeiro, Ana B.. "Elacridar as a modulator of Imatinib resistance". Paper presented in CIMAGO Annual Scientific Meeting 2018, 2018.
  89. Ferreira, Catarina; Jorge, Joana; Alves, Raquel; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana B.. "As vias WNT/ß-catenina e Hedgehog como alvos terapêuticos em neoplasias Linfóides B". Paper presented in Reunião Anual da Sociedade Portuguesa de Hematologia, 2017.
  90. Neves, Joana; Jorge, Joana; Alves, Raquel; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana B.. "Potencial terapêutico do Parthenolide no tratamento de Leucemias Linfoblásticas Agudas B e T". Paper presented in Reunião Anual da Sociedade Portuguesa de Hematologia, 2017.
  91. Jorge, Joana; Alves, Raquel; Gonçalves, Ana Cristina; Almeida, António M.; Sarmento-Ribeiro, Ana B.. "Elacridar como modulador da resistência ao Imatinib". Paper presented in Reunião Anual da Sociedade Portuguesa de Hematologia, 2017.
  92. Ribau, Beatriz; Jorge, Joana; Alves, Raquel; Ribeiro, Ilda P; Gonçalves, Ana Cristina; Marques Carreira, Isabel; Sarmento-Ribeiro, Ana B.. "Epigenetic modifications as targets to new therapies for Chronic Lymphocytic leukaemia – A preliminary study". Paper presented in 12th YES Meeting, 2017.
  93. Fernandes, Joana; Gonçalves, Ana Cristina; Alves, Raquel; Jorge, Joana; Sarmento-Ribeiro, Ana B.. "Potencial terapêutico do sirolimus e da metformina em Leucemia Linfoblástica Aguda". Paper presented in Reunião Anual da Sociedade Portuguesa de Hematologia, 2016.
  94. Corredeira, P; Gonçalves, Ana Cristina; Jorge, Joana; Pires, Ana; Alves, Raquel; Sarmento-Ribeiro, Ana B.. "Avaliação de mecanismos de resistência à azacitidina num modelo in vitro de Leucemia Mieloide Aguda". Paper presented in Reunião Anual da Sociedade Portuguesa de Hematologia, 2016.
  95. Jorge, Joana; Gonçalves, Ana Cristina; Cortesao, Emília; Geraldes, Catarina; Gomes, B.; Pires, Ana; Fernandes, Sara; et al. "NFE2L2 and KEAP1 gene expression in Myelodysplastic Syndrome and Monoclonal Gammophaties". Paper presented in 2nd ASPIC International Congress, 2016.
  96. Pires, Ana; Jorge, Joana; Alves, Raquel; Gonçalves, Ana Cristina; Coucelo, Margarida; Azevedo, Joana; Brito, M.J.; et al. "The role of WNT and Hedgehog signaling pathways as novel prognostic biomarkers and therapeutic targets". Paper presented in 2nd ASPIC International Congress, 2016.
  97. Jorge, Joana; Gonçalves, Ana Cristina; Cortesao, Emília; Geraldes, Catarina; Pires, Ana; Fernandes, Sara; Alves, Raquel; Ribeiro, Letícia; Sarmento-Ribeiro, Ana B.. "NFE2L2 and KEAP1 gene expression analysis in Hematological Malignancies – Clinical implications". Paper presented in 5thCIMAGO Congress, 2016.
  98. Pires, Ana; Jorge, Joana; Alves, Raquel; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana B.. "The embrionary signaling pathways as therapeutic targets in Acute Lymphoblastic Leukemia". Paper presented in 5thCIMAGO Congress, 2016.
  99. Ribeiro, Mariana; Goncalves, Ana Cristina; Jorge, Joana; Cortesao, Emília; Loureiro, L.; Pereira, Amélia; Ribeiro, Letícia; Sarmento-Ribeiro, Ana B.. "Relação entre os polimorfismos em enzimas do ciclo do carbono e a Síndrome Mielodisplásica". Paper presented in Reunião Anual da Sociedade de Portuguesa de Hematologia, 2015.
  100. Jorge, Joana; Gonçalves, Ana Cristina; Cortesao, Emília; Pires, Ana; Fernandes, Sara; Alves, Raquel; Ribeiro, Letícia; Sarmento-Ribeiro, Ana B.. "Análise dos níveis de expressão dos genes NFE2L2 e KEAP1 em doentes com Síndrome Mielodisplásica – Implicações no diagnóstico e prognóstico". Paper presented in Reunião Anual da Sociedade de Portuguesa de Hematologia, 2015.
  101. Jorge, Joana; Pires, Ana; Alves, Raquel; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana B.. "O L744,832 e Everolimus induzem efeitos citotóxicos e citostáticos em células de Linfoma não Hodgkin agressivos". Paper presented in Reunião Anual da Sociedade Portuguesa de Hematologia, 2015.
  102. Fernandes, Sara; Gonçalves, Ana Cristina; Geraldes, Catarina; Jorge, Joana; Alves, Raquel; Pires, Ana; Veiga, Sara; et al. "Polymorphisms in Transporter and Metabolizing Proteins – Role in Monoclonal Gammopathies' Development". Paper presented in 10th YES Meeting, 2015.
  103. Ferreira, Mariana; Jorge, Joana; Gonçalves, Ana Cristina; Alves, Raquel; Fernandes, Sara; Pires, Ana; Veiga, Sara; et al. "Methionine Synthase Polymorphism influence P15 and P16 Methylation status". Paper presented in 10th YES Meeting, 2015.
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  105. Fernandes, Sara; Jorge, Joana; Gonçalves, Ana Cristina; Alves, Raquel; Pires, Ana; Veiga, Sara; Cortesao, Emília; et al. "Polymorphisms in ABC transporters – Role in the development of myeloid neoplasias.". Paper presented in 1st Poster Contest by AstraZeneca Foundation in In4Med, 2015.
  106. Pires, Ana; Alves, Raquel; Balca-Silva, J.; Jorge, Joana; Fernandes, Sara; Veiga, Sara; Domingues, C.; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana B.. "Inhibition of metaloproteinases induces apoptosis and cell cycle arrest in hematological neoplasias". Paper presented in 1st Poster Contest by AstraZeneca Foundation in In4Med, 2015.
  107. Fernandes, Sara; Jorge, Joana; Gonçalves, Ana Cristina; Alves, Raquel; Pires, Ana; Veiga, Sara; Cortesao, Emília; et al. "Influence of the ABC Transposters' Genetic Profiles in the Development of Myeloid Neoplasias". Paper presented in 4th CIMAGO Congress, 2015.
  108. Gonçalves, Ana Cristina; Alves, Raquel; Pires, Ana; Jorge, Joana; Mota-Vieira, Luisa; Nascimento Costa, José M.; Sarmento-Ribeiro, Ana B.. "Chronic Exposure to Oxidative Stress inducers influence Methylation Status in Normal and Neoplastic Hematological Cells". Paper presented in 4th CIMAGO Congress, 2015.
  109. Gonçalves, Ana Cristina; Alves, Raquel; Pires, Ana; Jorge, Joana; Baldeiras, I.; Cortesao, Emília; Carda, José Pedro; et al. "The Interplay between Oxidative Stress and DNA Methylation – Role in Development, Diagnosis and Prognosis of Myeloid Neoplasias". Paper presented in 4thCIMAGO Congress, 2015.
  110. Jorge, Joana; Cortesao, Emília; Gonçalves, Ana Cristina; Pires, Ana; Alves, Raquel; Mocho, C.; Rito, Luis; et al. "DNA Methylation status in Bone Marrow vs Peripheral Blood - A comparative study in Myelodysplastic Syndrome". Paper presented in 18th Reunião da Sociedade Portuguesa de Genética Humana, 2014.
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  111. Gonçalves, Ana Cristina; Alves, Raquel; Pires, Ana; Jorge, Joana; Nascimento Costa, José M.; Mota-Vieira, Luisa; Sarmento-Ribeiro, Ana B.. "Exposição Crónica a Stress Oxidativo induz alteração na metilação e expressão génica – Influência na Patogénese e Agressividade de Neoplasias Hematológicas". Paper presented in Reunião Anual da Sociedade Portuguesa de Hematologia, 2014.
  112. Jorge, Joana; Cortesao, Emília; Gonçalves, Ana Cristina; Pires, Ana; Alves, Raquel; Mocho, C.; Rito, Luis; et al. "Gene methylation in Myelodysplastic Syndrome – A comparative study between Bone Marrow and Peripheral Blood". Paper presented in ESMO Congress, 2014.
  113. Fernandes, Sara; Jorge, Joana; Gonçalves, Ana Cristina; Alves, Raquel; Pires, Ana; Veiga, Sara; Cortesao, Emília; et al. "MDR1 (C3435T) and MRP1 (G1666A) polymorphisms - Role in myeloid neoplasias development". Paper presented in 9th YES Meeting, 2014.
  114. Pires, Ana; Alves, Raquel; Jorge, Joana; Balca-Silva, J.; Domingues, C.; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana B.. "Inhibition of Metalloproteinases induces apoptosis and cell cycle arresting hematological neoplasias". Paper presented in 9th YES Meeting, 2014.
  115. Cortesao, Emília; Jorge, Joana; Gonçalves, Ana Cristina; Pires, Ana; Alves, Raquel; Mocho, C.; Rito, C.; et al. "DAPK and TRAIL receptors methylation status in Myelodysplastic Syndromes patients". Paper presented in 19th European Hematology Association Congress, 2014.
  116. Gonçalves, Ana Cristina; Jorge, Joana; Cortesao, Emília; Geraldes, Catarina; Espadana, A. I.; Magalhães, Emília; Mocho, C.; et al. "Avaliação do Perfil Epigenético em Neoplasias Hematológicas – Estudo comparativo entre amostras de Sangue Periférico e Medula Óssea". Paper presented in Reunião Anual da Sociedade Portuguesa de Hematologia, 2013.
  117. Pires, Ana; Jorge, Joana; Alves, Raquel; Domingues, C.; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana B.. "O microambiente medular como alvo terapêutico em neoplasias hematológicas – O papel dos inibidores das metaloproteinases da matriz". Paper presented in Reunião Anual da Sociedade Portuguesa de Hematologia, 2013.
  118. Domingues, C.; Ferreira, Mariana; Pires, C. ; Matias, C.; Lourenço, T.; Pires, Ana; Jorge, Joana; et al. "Vismodegib (GDC-0449): Nova abordagem terapêutica no tratamento de neoplasias hematológicas". Paper presented in Reunião Anual da Sociedade Portuguesa de Hematologia, 2013.
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  120. Pires, Ana; Jorge, Joana; Alves, Raquel; Domingues, C.; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana B.. "Matrix Metalloproteinases as a therapeutic target in Hematological Neoplasias". Paper presented in 4th PF2MUC Symposium, 2013.
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  123. Pires, Ana; Jorge, Joana; Alves, Raquel; Domingues, C.; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana B.. "Inhibition of metalloproteinases as a new therapeutic approach in Acute Promyelocytic Leukemia". Paper presented in 8th YES Meeting, 2013.
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  126. Pires, Ana; Jorge, Joana; Alves, Raquel; Domingues, C.; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana B.. "The Bone Marrow Microenvironment as a therapeutic target in Hematologic Neoplasias – The role of Matrix Metalloproteinases". Paper presented in 3th CIMAGO Congress, 2013.
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Journal article
  1. Magalhães, Mariana; Domínguez-Martín, Eva María; Jorge, Joana; Gonçalves, Ana Cristina; Massenzio, Francesca; Spigarelli, Renato; Ribeiro-Rodrigues, Teresa; et al. "Unveiling the antitumor mechanism of 7a-acetoxy-6ß-hydroxyroyleanone from Plectranthus hadiensis in glioblastoma". Journal of Ethnopharmacology 335 (2024): 118689. http://dx.doi.org/10.1016/j.jep.2024.118689.
    10.1016/j.jep.2024.118689
  2. Alves, Raquel; Pires, Ana; Jorge, Joana; Balça-Silva, Joana; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana Bela. "Batimastat Induces Cytotoxic and Cytostatic Effects in In Vitro Models of Hematological Tumors". International Journal of Molecular Sciences 25 8 (2024): 4554. http://dx.doi.org/10.3390/ijms25084554.
    10.3390/ijms25084554
  3. Marto, Carlos Miguel; Laranjo, Mafalda; Gonçalves, Ana Cristina; Paula, Anabela; Jorge, Joana; Caetano-Oliveira, Rui; Sousa, Maria Inês; et al. "In Vitro Characterization of Reversine-Treated Gingival Fibroblasts and Their Safety Evaluation after In Vivo Transplantation". Pharmaceutics 16 2 (2024): 207. http://dx.doi.org/10.3390/pharmaceutics16020207.
    10.3390/pharmaceutics16020207
  4. Lapa, Beatriz Santos; Costa, Maria Inês; Figueiredo, Diana; Jorge, Joana; Alves, Raquel; Monteiro, Ana Raquel; Serambeque, Beatriz; et al. "AZD-7648, a DNA-PK Inhibitor, Induces DNA Damage, Apoptosis, and Cell Cycle Arrest in Chronic and Acute Myeloid Leukemia Cells". International Journal of Molecular Sciences 24 20 (2023): 15331. http://dx.doi.org/10.3390/ijms242015331.
    10.3390/ijms242015331
  5. Ribeiro, Hugo; Alves, Raquel; Jorge, Joana; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana Bela; Teixeira-Veríssimo, Manuel; Andrade, José Paulo; Dourado, Marília. "Monocytes in the Characterization of Pain in Palliative Patients with Severe Dementia—A Pilot Study". International Journal of Molecular Sciences 24 13 (2023): 10723. http://dx.doi.org/10.3390/ijms241310723.
    10.3390/ijms241310723
  6. Jorge, Joana; Neves, Joana; Alves, Raquel; Geraldes, Catarina; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana Bela. "Parthenolide Induces ROS-Mediated Apoptosis in Lymphoid Malignancies". International Journal of Molecular Sciences 24 11 (2023): 9167. http://dx.doi.org/10.3390/ijms24119167.
    10.3390/ijms24119167
  7. Ribeiro, Hugo; Alves, Raquel; Jorge, Joana; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana Bela; Teixeira-Veríssimo, Manuel; Dourado, Marília; Andrade, José Paulo. "Platelet Membrane Proteins as Pain Biomarkers in Patients with Severe Dementia". Biomedicines 11 2 (2023): 380. http://dx.doi.org/10.3390/biomedicines11020380.
    10.3390/biomedicines11020380
  8. Alves, Raquel; Santos, Diogo; Jorge, Joana; Gonçalves, Ana Cristina; Catarino, Steve; Girão, Henrique; Melo, Joana Barbosa; Sarmento-Ribeiro, Ana Bela. "Alvespimycin Inhibits Heat Shock Protein 90 and Overcomes Imatinib Resistance in Chronic Myeloid Leukemia Cell Lines". Molecules 28 3 (2023): 1210. http://dx.doi.org/10.3390/molecules28031210.
    10.3390/molecules28031210
  9. Magalhães, Mariana; Domínguez-Martín, Eva María; Jorge, Joana; Gonçalves, Ana Cristina; Díaz-Lanza, Ana María; Manadas, Bruno; Efferth, Thomas; Rijo, Patrícia; Cabral, Célia. "Parvifloron D-based potential therapy for glioblastoma: Inducing apoptosis via the mitochondria dependent pathway". Frontiers in Pharmacology 13 (2022): http://dx.doi.org/10.3389/fphar.2022.1006832.
    10.3389/fphar.2022.1006832
  10. Jorge, Joana; Magalhães, Nisa; Alves, Raquel; Lapa, Beatriz; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana Bela. "Antitumor Effect of Brusatol in Acute Lymphoblastic Leukemia Models Is Triggered by Reactive Oxygen Species Accumulation". Biomedicines 10 9 (2022): 2207. http://dx.doi.org/10.3390/biomedicines10092207.
    10.3390/biomedicines10092207
  11. Alves, Raquel; Gonçalves, Ana Cristina; Jorge, Joana; Marques, Gilberto; Ribeiro, André B.; Tenreiro, Rita; Coucelo, Margarida; et al. "Genetic Variants of ABC and SLC Transporter Genes and Chronic Myeloid Leukaemia: Impact on Susceptibility and Prognosis". International Journal of Molecular Sciences 23 17 (2022): 9815. http://dx.doi.org/10.3390/ijms23179815.
    10.3390/ijms23179815
  12. Alves, Raquel; Gonçalves, Ana Cristina; Jorge, Joana; Almeida, António M.; Sarmento-Ribeiro, Ana Bela. "Combination of Elacridar with Imatinib Modulates Resistance Associated with Drug Efflux Transporters in Chronic Myeloid Leukemia". Biomedicines 10 5 (2022): 1158. http://dx.doi.org/10.3390/biomedicines10051158.
    10.3390/biomedicines10051158
  13. Costa, Maria Inês; Santos Lapa, Beatriz; Jorge, Joana; Alves, Raquel; Carreira, Isabel Marques; Sarmento-Ribeiro, Ana Bela; Gonçalves, Ana Cristina. "Zinc Prevents DNA Damage in Normal Cells but Shows Genotoxic and Cytotoxic Effects in Acute Myeloid Leukemia Cells". International Journal of Molecular Sciences 23 5 (2022): 2567. http://dx.doi.org/10.3390/ijms23052567.
    Published • 10.3390/ijms23052567
  14. Jorge, Joana. "Impact of cancer metabolism on therapy resistance – Clinical implications". Drug Resistance Updates (2021): 100797-100797. http://dx.doi.org/10.1016/j.drup.2021.100797.
    10.1016/j.drup.2021.100797
  15. Fonseca, Élisa; Marques, Carla Cruz; Pimenta, Jorge; Jorge, Joana; Baptista, Maria Conceição; Gonçalves, Ana Cristina; Pereira, Rosa M. L. N.. "Anti-Aging Effect of Urolithin A on Bovine Oocytes In Vitro". Animals 11 7 (2021): 2048. http://dx.doi.org/10.3390/ani11072048.
    10.3390/ani11072048
  16. Gonçalves, Ana Cristina; Alves, Raquel; Baldeiras, Inês; Jorge, Joana; Marques, Bárbara; Paiva, Artur; Oliveiros, Bárbara; et al. "Oxidative Stress Parameters Can Predict the Response to Erythropoiesis-Stimulating Agents in Myelodysplastic Syndrome Patients". Frontiers in Cell and Developmental Biology 9 (2021): http://dx.doi.org/10.3389/fcell.2021.701328.
    10.3389/fcell.2021.701328
  17. Martins, Ivana; Ribeiro, Ilda Patrícia; Jorge, Joana; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana Bela; Melo, Joana Barbosa; Carreira, Isabel Marques. "Liquid Biopsies: Applications for Cancer Diagnosis and Monitoring". Genes 12 3 (2021): 349. http://dx.doi.org/10.3390/genes12030349.
    Published • 10.3390/genes12030349
  18. Jorge, Joana; Gonçalves, Ana Cristina; Cortesão, Emília; Pires, Ana Cláudia; Alves, Raquel; Geraldes, Catarina; Pereira, Amélia; et al. "Can peripheral blood provide good DNA methylation biomarkers in myelodysplastic syndrome?". Journal of Molecular and Clinical Medicine 4 1 (2021): 39. http://dx.doi.org/10.31083/j.jmcm.2021.01.015.
    10.31083/j.jmcm.2021.01.015
  19. Lapa, Beatriz; Gonçalves, Ana Cristina; Jorge, Joana; Alves, Raquel; Pires, Ana Salomé; Abrantes, Ana Margarida; Coucelo, Margarida; et al. "Acute myeloid leukemia sensitivity to metabolic inhibitors: glycolysis showed to be a better therapeutic target". Medical Oncology 37 8 (2020): http://dx.doi.org/10.1007/s12032-020-01394-6.
    10.1007/s12032-020-01394-6
  20. Magalhães, Mariana; Jorge, Joana; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana Bela; Carvalho, Rui; Figueiras, Ana; Santos, Ana Cláudia; Veiga, Francisco. "miR-29b and retinoic acid co-delivery: a promising tool to induce a synergistic antitumoral effect in non-small cell lung cancer cells". Drug Delivery and Translational Research (2020): http://dx.doi.org/10.1007/s13346-020-00768-7.
    10.1007/s13346-020-00768-7
  21. Jorge, Joana; Petronilho, Sara; Alves, Raquel; Coucelo, Margarida; Gonçalves, Ana Cristina; Nascimento Costa, José Manuel; Sarmento-Ribeiro, Ana Bela. "Apoptosis induction and cell cycle arrest of pladienolide B in erythroleukemia cell lines". Investigational New Drugs 38 2 (2020): 369-377. http://dx.doi.org/10.1007/s10637-019-00796-2.
    10.1007/s10637-019-00796-2
  22. Alves, Raquel; Gonçalves, Ana Cristina; Jorge, Joana; Marques, Gilberto; Luís, Dino; Ribeiro, André B.; Freitas-Tavares, Paulo; et al. "MicroRNA signature refine response prediction in CML". Scientific Reports 9 1 (2019): http://dx.doi.org/10.1038/s41598-019-46132-9.
    Published • 10.1038/s41598-019-46132-9
  23. Alves, Raquel; Goncalves, Ana Cristina; Jorge, Joana; Alves, Joana; da Silva, Antonio Alves; Freitas-Tavares, Paulo; Nascimento Costa, Jose M.; Almeida, Antonio M.; Sarmento-Ribeiro, Ana B.. "Everolimus in combination with Imatinib overcomes resistance in Chronic myeloid leukaemia". Medical Oncology 36 3 (2019): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000459408700001&KeyUID=WOS:000459408700001.
    Published • 10.1007/s12032-019-1253-5
  24. Magalhaes, Mariana; Almeida, Mauro; Tavares-da-Silva, Elisiario; Roleira, Fernanda M. F.; Varela, Carla; Jorge, Joana; Goncalves, Ana Cristina; et al. "miR-145-loaded micelleplexes as a novel therapeutic strategy to inhibit proliferation and migration of osteosarcoma cells". European Journal of Pharmaceutical Sciences 123 (2018): 28-42. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000443566100004&KeyUID=WOS:000443566100004.
    Published • 10.1016/j.ejps.2018.07.021
  25. Mendes, J.; Gonçalves, A.C.; Alves, R.; Jorge, J.; Pires, A.; Ribeiro, A.; Sarmento-Ribeiro, A.B.. "L744,832 and Everolimus Induce Cytotoxic and Cytostatic Effects in Non-Hodgkin Lymphoma Cells". Pathology and Oncology Research 22 2 (2016): 301-309. http://www.scopus.com/inward/record.url?eid=2-s2.0-84961205328&partnerID=MN8TOARS.
    Published • 10.1007/s12253-015-9998-4
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2024/01 Can tumor educated platelets identify and predict survival of multiple myeloma patients? (as presenting author) IV Metabolism, Ageing & Disease (MAD) Meeting
(Coimbra, Portugal)
2024/01 DNA-PK inhibition as new therapeutic approach in acute myeloblastic leukemia – an in vitro study. IV Metabolism, Ageing & Disease (MAD) Meeting
(Coimbra, Portugal)
2024/01 Zinc synergizes with cytarabine and olaparib increasing apoptosis and DNA damage in acute myeloblastic leucemia
(Coimbra, Portugal)
2024/01 Can tumor educated platelets identify and predict survival of multiple myeloma patients? (as presenting author) CIMAGO Congress
(Coimbra, Portugal)
2024/01 Therapeutic efficacy of PARP and CHK1 inhibition in combination with cytarabine in acute myeloblastic leukemia: preliminary study in vitro CIMAGO Congress
(Coimbra, Portugal)
2024/01 Dedifferentiated gingival fibroblasts present stem-like properties and multilineage-differentiation capacity CIMAGO Congress
(Coimbra, Portugal)
2023/11 Plaquetas educadas pelos tumores como fonte de biomarcadores de diagnóstico e sobrevivência no mieloma múltiplo (as presenting author) Reunião Anual da Sociedade Portuguesa de Hematologia
Sociedade Portuguesa de Hematologia (Viseu, Portugal)
2023/11 Inibição da glutaminólise na resistência ao imatinib na leucemia mieloide crónica: Estudo in vitro. Reunião Anual da Sociedade de Portuguesa de Hematologia
Sociedade Portuguesa de Hematologia (Viseu, Portugal)
2023/11 DNA-PK como alvo terapêutico na leucemia mieloblástica aguda: Um estudo in vitro Reunião Anual da Sociedade de Portuguesa de Hematologia
Sociedade Portuguesa de Hematologia (Viseu, Portugal)
2023/05 Plaquetas: Nova abordagem no Cancro (as Presenting Author) PhDoing: Hoje Ciência, Inovação Amanhã
(Coimbra, Portugal)
2022/11 Mecanismos moleculares de resistência a imunomoduladores no mieloma múltiplo. Reunião Anual da Sociedade de Portuguesa de Hematologia
(Tróia, Portugal)
2022/11 Glutaminólise como alvo terapêutico na leucemia linfocítica crónica (as Presenting Author) Reunião Anual da Sociedade de Portuguesa de Hematologia
(Tróia, Portugal)
2022/06/30 Zn in the modulation of the DNA damage response: preventive, genotoxic, and cytotoxic roles in acute myeloid leukemia STRATAGEM - Annual Conference
(Coimbra, Portugal)
2021/04 The role of micronutrients in the DNA damage response: the case of zinc in acute myeloid leukemia In4Med 2021
(Portugal)
2021 O zinco na modulação dos efeitos antiproliferativos e citotóxicos do olaparib e citarabina na Leucemia Mielóide Aguda Reunião Anual da Sociedade Portuguesa de Hematologia
Sociedade Portuguesa de Hematologia (Espinho)
2021 Avaliação do potencial terapêutico de moduladores do NRF2 em doentes com leucemia linfocítica crónica. Reunião Anual da Sociedade de Portuguesa de Hematologia
Sociedade Portuguesa de Hematologia (Espinho)
2021 Potencial terapêutico de moduladores epigenéticos na leucemia linfocítica crónica. (as Presenting author) Reunião Anual da Sociedade de Portuguesa de Hematologia
Sociedade Portuguesa de Hematologia (Espinho)
2021 Unravelling resistance mechanisms to proteasome inhibitors in multiple multiple 4th Annual Conference STRATAGEM CA17104
STRATAGEM CA17104 (Prague, Czech Republic)
2021 Oxidative stress parameters can predict the response to erythropoiesis-stimulating agents in myelodysplastic syndrome patients. 4th Annual Conference STRATAGEM CA17104
STRATAGEM CA17104 (Prague, Czech Republic)
2021 Angiogenesis stimulation of cryopreserved ovarian tissue 27th European Congress of Obstetrics and Gynaecology (EBCOG)
(Athens, Greece)
2020/11 Resistência adquirida a inibidores de proteasoma em mieloma múltiplo: Estudos in vitro Reunião Anual da Sociedade Portuguesa de Hematologia
Sociedade Portuguesa de Hematologia
2020/11 Drug response prediction in CML: the value of microRNAs expression profile International Online Symposium on “New Therapeutic Tools Against Preclinical Models of Multidrug Resistant Tumors”,
2020/09 Mecanismos moleculares associados à resistência adquirida a inibidores de proteasoma em mieloma múltiplo: Estudos in vitro 2º encontro nacional de Jovens Investigadores em Oncologia
Liga Portuguesa Contra o Cancro
2019/11 STAT5 – Um alvo terapêutico em Leucemia linfoblástica aguda? Reunião Anula da Sociedade Portuguesa de Hematologia
(Braga, Portugal)
2019/11 Transportadores de influxo/efluxo na Leucemia mieloide cronica: Influência das variantes genéticas na susceptibilidade e na resposta à terapêutica Reunião Anula da Sociedade Portuguesa de Hematologia
(Braga, Portugal)
2019/01 Therapeutic potential of gambogic acid and silibinin in acute myeloblastic leukemia - In vitro In4Med 2019
Faculty of Medicine, University of Coimbra
2018/11 Metabolismo como alvo terapêutica na leucemia mieloide aguda – Glicólise ou Fosforilação oxidativa? Reunião Anual da Sociedade Portuguesa de Hematologia
Sociedade Portuguesa de Hematologia (Portugal)
2018/11 Alvespimicina: Nova arma terapêutica na leucemia mieloide crónica. Reunião Anual da Sociedade Portuguesa de Hematologia
Sociedade Portuguesa de Hematologia (Portugal)
2018/11 Papel da variabilidade genética das DNA metiltransferases na predisposição e prognóstico da leucemia linfocítica crónica. Reunião Anual da Sociedade Portuguesa de Hematologia
Sociedade Portuguesa de Hematologia (Portugal)
2018/01 Aldehyde Dehydrogenases as potential biomarkers in Myeloid Neoplasias CIMAGO Annual Scientific Meeting
Centro de Investigação em Meio Ambiente, Genética e Oncobiologia (Portugal)
2018 Alvespimycin is a promising drug in resistant Chronic Myeloid Leukemia 13º YES Meeting
(Porto, Portugal)
2017/11 Modulação epigenética em Leucemia Linfoblástica Aguda B – Potencial terapêutico dos Agentes Hipometilantes e Inibidores das Desacetilases das Histonas Reunião Anual da Sociedade Portuguesa de Hematologia
Sociedade Portuguesa de Hematologia (Portugal)
2017/11 Perfil de microRNAs na LMC – Potencial biomarcador de resposta ao Imatinib. Reunião Anual da Sociedade Portuguesa de Hematologia
Sociedade Portuguesa de Hematologia (Portugal)
2017/09 ALDHs as potential biomarkers in myeloid neoplasms – Preliminary study. 12º YES Meeting
Faculty of Medicine of the University of Porto (Portugal)
2017/09 WNT/ß-catenin and Hedgehog signaling pathways as therapeutic targets in B-cell neoplasms 12º YES Meeting
Faculty of Medicine of the University of Porto (Portugal)
2017/09 Cytotoxic effects of parthenolide on lymphoid malignancies’ cell lines 12º YES Meeting
Faculty of Medicine of the University of Porto (Portugal)
2017/02 NFE2L2 expression as a predictor of AML transformation in Myelodysplastic Syndrome. In4Med
Núcleo de Estudantes de Medicina da Associação Académica de Coimbra (Portugal)
2017/02 The relevance of molecular profile in response to WNT inhibitors in Acute Myeloid Leukemia. In4Med
Núcleo de Estudantes de Medicina da Associação Académica de Coimbra (Portugal)
2016/11 Papel da variabilidade genética da via KEAP1-NRF2 na susceptibilidade e prognóstico de doentes com Leucemia Linfocítica Crónica. Reunião Anual da Sociedade Portuguesa de Hematologia
Sociedade Portuguesa de Hematologia (Portugal)
2015/11 Avaliação do Potencial Terapêutico da inibição da via WNT em modelos in vitro de Neoplasias Hematológicas. Reunião Anual da Sociedade de Portuguesa de Hematologia
Sociedade de Portuguesa de Hematologia (Portugal)
2014/11 Influência do Perfil Genético de Transportadores ABC no Desenvolvimento de Neoplasias Mieloides. Reunião Anual da Sociedade de Portuguesa de Hematologia
Sociedade de Portuguesa de Hematologia (Portugal)
2014/09 Methylation pattern in Myelodysplastic Syndrome – Comparative study between Bone Marrow And Peripheral Blood 9º YES Meeting
Faculty of Medicine of the University of Porto (Portugal)
2013/09 The role of Vismodegib in Hematological Neoplasias Treatment 8º YES Meeting
Faculty of Medicine of the University of Porto (Portugal)

Supervision

Thesis Title
Role
Degree Subject (Type)
Institution / Organization
2023/09 - 2024/10 Therapeutic potential of parthenolide on B-cell haematologic malignancies.
Co-supervisor
Mestrado em Investigação Biomédica (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2022/09 - 2023/09/21 Inibição do NRF2 como nova abordagem terapêutica em neoplasias linfoides sensíveis e resistente ao bortezomib - Estudo preliminar
Co-supervisor
Mestrado em Química Medicinal (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2021 - 2022 Therapeutic Potential of the Drug Buparlisib in Chronic Myeloid Leukemia: Role in Imatinib Resistance
Co-supervisor
Biochemistry (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2019 - 2021 Potencial terapêutico de moduladores do NRF2 na leucemia linfoblástica aguda- Estudos in vitro
Co-supervisor
Master in Chemical Medicine (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2018 - 2019 O potencial terapêutico de sirolimus e metformina na leucemia linfoblástica aguda em idade pediátrica
Co-supervisor
Universidade de Coimbra Faculdade de Medicina, Portugal

Event organisation

Event name
Type of event (Role)
Institution / Organization
2023/09/30 - Current PicNic com Saúde @CBR (2023/09/30)
Festival (Member of the Organising Committee)
Coimbra Institute for Clinical and Biomedical Research, Portugal
2022/07/09 - Current PicNic com Saúde @CBR (2022/07/09)
Festival (Member of the Organising Committee)
Coimbra Institute for Clinical and Biomedical Research, Portugal
2023/05/26 - 2023/05/27 PhDoing: Hoje Ciência, Inovação Amanhã (2023/05/26 - 2023/05/27)
Meeting (Member of the Organising Committee)
Universidade de Coimbra Instituto de Investigação Clínica e Biomédica de Coimbra, Portugal
2022/06/29 - 2022/07/01 Annual Congress and Training School of STRATAGEM (COST Action 17104) (2022/06/29)
Congress (Member of the Organising Committee)
Universidade de Coimbra Faculdade de Medicina, Portugal

Event participation

Activity description
Type of event
Event name
Institution / Organization
2023/09/29 - Current European Researchers' Night 2023 Coimbra European Researchers' Night 2023 Coimbra
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2022/09/30 - Current European Researchers' Night '22'23 Coimbra "Ciência Para todos, sustentabilidade e inclusão"
Other
European Researchers' Night '22'23 Coimbra
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2016/10 - 2016/10 Coimbra One-Day Workshop on Multiplex ELISPOT
Seminar
Coimbra One-Day Workshop on Multiplex ELISPOT
2016/10 - 2016/10 Investigação Translacional em Hemato-Oncologia: das moléculas à clínica
Seminar
Investigação Translacional em Hemato-Oncologia: das moléculas à clínica
2016/04 - 2016/04 Let’s talk about CRISPR
Seminar
Let’s talk about CRISPR
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2012/12 - 2012/12 Alternatives to Animal Use in Pre-Clinical Studies
Seminar
Alternatives to Animal Use in Pre-Clinical Studies
Biocant Associação de Transferência de Tecnologia, Portugal

Jury of academic degree

Topic
Role
Candidate name (Type of degree)
Institution / Organization
2024/10/28 Biomarcadores de dor em doentes em cuidados paliativos
(Thesis) Main arguer
Guilherme dos Santos Rodrigues (Other)
Instituto Politécnico de Coimbra Escola Superior Agrária de Coimbra, Portugal
2024/10/22 Therapeutic potential of parthenolide on B-cell haematologic malignancies.
Supervisor
Mara Amuji da Silveira Baptista (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2023/09/21 Inibição do NRF2 como nova abordagem terapêutica em neoplasias linfoides sensíveis e resistente ao bortezomib - Estudo preliminar
Thesis Member
Maria Rui Marques Lopes (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2023/09/08 Brusatol, um inibidor do NRF2, como nova estratégia terapêutica no mieloma múltiplo resistente ao bortezomib.
Thesis Member
Ana Sofia Santos Rainho (Other)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2021 Avaliação das necessidades e das discrepâncias de respostas sociais nos Cuidados Paliativos a nível nacional: A formação e o papel do Assistente Social nas Equipas de Cuidados Paliativos
Thesis Member
Adriana Filipa Fonseca Bernardino (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal

Association member

Society Organization name Role
2020/06 - Current European Hematology Association
2020/03 - Current European Association for Cancer Research
2019/12 - Current Associação Portuguesa de Investigação em Cancro

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2018/01 - Current Practical Hematology Classes in Mestrado em Análises Clínicas (Mestrado) Universidade de Coimbra Faculdade de Farmácia, Portugal

Mentoring / Tutoring

Topic Student name
2015/09 - Current Exchange Programme from Núcleo de Estudantes de Medicina da Faculdade de Medicina da Universidade de Coimbra Students that have selected Laboratory of Oncobiology and Hematology for the exchange project
2015/09 - Current Students Investigation Support Students that selected Laboratory of Oncobiology and Hematology for their investigation projects
Distinctions

Award

2024 1º Prémio Poster Trabalho Experimental (as Co-author)
Sociedade Portuguesa de Hematologia, Portugal
2023 1º Prémio Poster Trabalho Experimental (as Co-author)
Sociedade Portuguesa de Hematologia , Portugal
2021 1st Prize Oral communication
Sociedade Portuguesa de Hematologia , Portugal
2020 1st Prize for Best Speed-Talks/Posters (as co-author)
2020 1st Prize Oral communication Experimental Work (as co-author)
Sociedade Portuguesa de Hematologia , Portugal
2019 1st Prize Fundamental Research Poster (as co-author)
2019 Best Work (as co-author)
2019 Best Poster (as co-author)
2019 2º Prémio Poster Trabalho Experimental (as co-author)
2018 3th Best Oral Communication (as co-author)
2018 1st Prize Experimental Work Poster (as co-author)
2018 1st Price for Best Poster in Molecular Biology & Oncology (as co-author)
2017 Best Oral Communication in Translational Research (as co-author)
2016 2nd Prize Oral Communication (as co-author)
2015 1st Prize Experimental Work Poster(as 1st author)
2014 1st Price for Best Poster in Molecular Biology & Oncology (as co-author)
2013 1st Price for Best Experimental Poster (as co-author)
2013 1st Price for Best Poster in Molecular Biology & Oncology (as 1st author)