Personal identification

Full name

Carla Sofia Trindade da Costa

Citation names

• Costa, Carla

Author identifiers

Ciência ID

411A-17DD-91E1

ORCID iD

0000-0002-0027-8462

Researcher Id

K-4048-2014

Scopus Author Id

55984029000

Email addresses

• carla.trindade@insa.min-saude.pt (Professional)
• cstcosta@gmail.com (Personal)

Telephones

Fax

• 223401149 (Professional)

Telephone

• 223401147 (Professional)

Addresses

• Instituto Nacional de Saúde Dr. Ricardo Jorge, Rua Alexandre Herculano, 321, 4000-055, Porto, Porto, Portugal (Professional)

Websites

• https://ispup.up.pt/en/pessoas/carla-costa-2/ (Professional)

Knowledge fields

• Medical and Health Sciences - Health Sciences - Public and Environmental Health

	Degree	Classification
2012 Concluded	PhD in Biomedical Sciences (Doutoramento) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal "Pesticides and Health in Agriculture.Genetic Damage" (THESIS/DISSERTATION)	Aprovado com distinção
2004 Concluded	Biology (Licenciatura) Major in Scientific Universidade do Porto Faculdade de Ciências, Portugal "Efeitos genotóxicos em agricultores" (THESIS/DISSERTATION)	15

Science

	Category Host institution	Employer
2021/04/12 - Current	Auxiliary Researcher (Research)	Instituto Nacional de Saúde Doutor Ricardo Jorge, Portugal
2021 - Current	Researcher (Research)	Universidade do Porto Laboratório Associado para a Investigação Integrativa e Translacional em Saúde Populacional, Portugal
2015/04/12 - Current	Researcher (Research)	Universidade do Porto Unidade de Investigação em Epidemiologia, Portugal
	Universidade do Porto Unidade de Investigação em Epidemiologia, Portugal
2014/08/01 - 2021/04/11	Postdoc (Research)	Fundação para a Ciência e a Tecnologia, Portugal
	Universidade do Porto Instituto de Saúde Pública, Portugal
2004/02/01 - 2021/04/11	Researcher (Research)	Instituto Nacional de Saúde Doutor Ricardo Jorge, Portugal
2019/03/18 - 2019/04/10	Visiting Researcher (Research)	Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele Pisana, Italy
2018/04/02 - 2018/04/11	Visiting Researcher (Research)	Universidade da Coruña, Spain
2017/03/13 - 2017/03/24	Visiting Researcher (Research)	Universidade da Coruña, Spain
2015/12/07 - 2015/12/18	Visiting Researcher (Research)	Universidade da Coruña, Spain
2014/05/26 - 2014/06/13	Visiting Researcher (Research)	Universidade da Coruña, Spain
2013 - 2014	Postdoc (Research)	Universidade do Porto Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares, Portugal
	Instituto Nacional de Saúde Doutor Ricardo Jorge Porto, Portugal
2012 - 2013	Research Assistant (Research)	Universidade do Porto Instituto de Saúde Pública, Portugal
	Instituto Nacional de Saúde Doutor Ricardo Jorge Porto, Portugal
2011/07/17 - 2011/08/12	Visiting Researcher (Research)	Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele Pisana, Italy
2011/02/03 - 2011/03/05	Visiting Researcher (Research)	CSIR-Indian Institute of Toxicology Research, India
2009/06/01 - 2009/11/30	Visiting Researcher (Research)	National Institute for Occupational Safety and Health Division of Applied Research and Technology, United States

Teaching in Higher Education

	Category Host institution	Employer
2015/09/01 - Current	Invited Adjunct Teacher (Polytechnic Teacher)	Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2015 - 2018	Invited Assistant Professor (University Teacher)	Universidade do Porto Faculdade de Medicina, Portugal
	Universidade do Porto Faculdade de Medicina, Portugal
2011 - 2013	Invited Assistant Professor (University Teacher)	Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
	Cooperativa de Ensino Superior Politécnico e Universitário, Portugal

Positions / Appointments

	Category Host institution	Employer
2021 - 2023	Lab Leader of the Lifecourse Environmental Exposures Lab	Universidade do Porto Instituto de Saúde Pública, Portugal

Contract

	Designation	Funders
2022 - 2029	PARC - European Partnership for the Assessment of Risks from Chemicals 101057014 Researcher Instituto Nacional de Saúde Doutor Ricardo Jorge Porto, Portugal	European Commission Ongoing
2022/05/01 - 2025/04/30	EDC(Mind)2 - Promoting healthy indoor environments with spotlight on endocrine disruptors: elucidating the links between environmental exposure, neurodevelopment and social behavior in children PTDC/CTA-AMB/3040/2021 Researcher Universidade do Porto Instituto de Saúde Pública, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2022/01/31 - 2025/01/31	ToxLearn4EU - Toxicology Innovative Learning For Europe 9EF5F25E Researcher Universidade do Porto Instituto de Saúde Pública, Portugal	European Commission Ongoing
2019 - 2021	Assessment of indoor PM2.5 oxidative potential through antioxidant depletion in artificial respiratory tract lining fluid 2019-2.1.11-TÉT-2019-00010 Researcher Universidade do Porto Instituto de Saúde Pública, Portugal	National Research, Development and Innovation Office, Hungary Ongoing
2018 - 2021	NANOLEGATOX - When old meets new: A novelty study on the human uptake, genotoxicity and immunotoxicity of nanoparticles and legacy contaminants mixtures. PTDC/SAU-PUB/29651/2017 Researcher Universidade do Porto Instituto de Saúde Pública, Portugal	Fundação para a Ciência e a Tecnologia
2018 - 2021	NANOBIOBARRIERS - Unravelling the mechanisms underlying the effects of metal-based nanoparticles on biological barriers - a contribution towards the implementation of the safe-by-design concept. PTDC/MED-TOX/31162/2017 Researcher Universidade do Porto Instituto de Saúde Pública, Portugal	Fundação para a Ciência e a Tecnologia
2016 - 2020	COST Action CA15129 Diagnosis, Monitoring and Prevention of Exposure-Related Noncommunicable Diseases (DiMoPEx) CA15129 Researcher	Concluded
2016 - 2020	COST Action CA15132 The comet assay as a human biomonitoring tool (hCOMET) CA15132 Researcher	Concluded
2016 - 2019	NeoGene - Impact of transplacental exposure to tobacco smoke in the DNA of newborn. Genetic and epigenetic effects FAPESP/19914/2014 Principal investigator Instituto Nacional de Saúde Dr. Ricardo Jorge, Departamento de Saúde Ambiental, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2016 - 2019	HEBE - Health, Comfort and Energy in the Built Environment NORTE-01-0145-FEDER-000010 Researcher Universidade do Porto Instituto de Saúde Pública, Portugal	Comissao de Coordenacao e Desenvolvimento Regional do Norte Concluded
2016 - 2019	CERASAFE – Safe production and use of nanomaterials in the ceramic industry ERA-NET SIINN, SIINN/0004/2014 Researcher Instituto Nacional de Saúde Doutor Ricardo Jorge, Portugal	Fundação para a Ciência e a Tecnologia European Research Area networks for Safe Implementation of Innovative Nanoscience and Nanotechnology Concluded
2016 - 2019	MAGICOAT- Controlling the degradation of MAGnesium alloys for biomedical applications using Innovative smart COATings PTDC/CTMBIO/2170/2014 Researcher Universidade do Porto Instituto de Saúde Pública, Portugal	Fundação para a Ciência e a Tecnologia
2015 - 2019	NanoToxClass- Establishing nanomaterial grouping/ classification strategies according to toxicity and biological effects for supporting risk assessment. ERA-NET SIINN, ERA-SIINN/0001/2013 Researcher Universidade do Porto Instituto de Saúde Pública, Portugal	European Research Area networks for Safe Implementation of Innovative Nanoscience and Nanotechnology Concluded
2010 - 2013	GenFA- Occupational Exposure to Formaldehyde. Genotoxic Damage and Susceptibility evaluation in Pathology Anatomy Laboratory workers PTDC /SAU-ESA/102367/2008 Researcher Universidade do Porto Instituto de Saúde Pública, Portugal	Fundação para a Ciência e a Tecnologia
2010 - 2012	NanoLINEN- Nanotoxicology link between India and European nations Nanolinen Researcher Instituto Nacional de Saúde Doutor Ricardo Jorge, Portugal	European Research Area Network for Development and Integration of Indian and European Research Concluded
2006 - 2008	ToxPb - Lead Exposure. Contribution for the study of genetic and immunologic toxicity. Influence of genetic determinants. PDCT/SAU-OBS/59821/2004 Research Fellow Instituto Nacional de Saúde Doutor Ricardo Jorge, Portugal	Fundação para a Ciência e a Tecnologia

Publications

Book	Efeitos genotóxicos em agricultores. Portugal: Série Estudos ISHST. 2006.
Book chapter	Costa, Carla; Teixeira, João Paulo. "Biomonitoring". In Encyclopedia of Toxicology, 141-144. Elsevier, 2024. 10.1016/b978-0-12-824315-2.00343-2 Fernández-Bertólez, Natalia; Costa, Carla; Brandão, Fátima; Teixeira, João Paulo; Pásaro, Eduardo; Valdiglesias, Vanessa; Laffon, Blanca. "Toxicological Aspects of Iron Oxide Nanoparticles". In Nanotoxicology in Safety Assessment of Nanomaterials, 303-350. Springer International Publishing, 2022. 10.1007/978-3-030-88071-2_13 Laffon, B.; Fernández-Bertólez, N.; Costa, C.; Brandão, F.; Teixeira, J. P.; Pásaro, E.; Valdiglesias, V.. "Cellular and Molecular Toxicity of Iron Oxide Nanoparticles". In Adv Exp Med Biol, 199-213. 2018. 10.1007/978-3-319-72041-8_12 Kiliç, G.; Fernández-Bertólez, N.; Costa, C.; Brandão, F.; Teixeira, J. P.; Pásaro, E.; Laffon, B.; Valdiglesias, V.. "Chapter 6 - The Application, Neurotoxicity, and Related Mechanism of Iron Oxide Nanoparticles A2 - Jiang, Xinguo". edited by Gao, Huile, 127-150. 2017. http://dx.doi.org/10.1016/B978-0-12-804598-5.00006-4 Costa, Carla. "Human exposure to titanium dioxide nanoparticles and current toxicological data: an overview.". In Titanium Dioxide Nanoparticles: Characterization, Properties and Synthesis. 2017. Costa, Carla. "Effects of Occupational Exposure to Pesticides in Human Health". In Occupational Exposure and Health Risks. 2016. Costa, Carla; Teixeira, João Paulo. "The Comet Assay In Vivo in Humans". 219-239. 2014. Costa, C.; Teixeira, J. P.. "Biomonitoring". 483-484. Elsevier, 2014. 10.1016/b978-0-12-386454-3.01000-9 Costa, Carla. "Pesticides as DNA damage inducers". In New Research on DNA damage. 2008. Costa, Carla. "The Portuguese pesticide scenario". In Pesticide Research Trends. 2008.
Conference abstract	Coelho, P. S.; Silva, S. P.; Costa, S.; Costa, C.; Coelho, M.; Garcia-Leston, J.; Laffon, B.; Teixeira, J. P.; Garcia-Lestón, J.. "Alterations in lymphocyte subsets and TCR mutation frequencies in populations exposed to metal contamination-Panasqueira mine area (Portugal)". 2011. 10.1016/J.TOXLET.2011.05.184 Teixeira, Joao; Laffon, Blanca; Silva, Susana; Roma-Torres, Joana; Costa, Carla; Coelho, Patricia; Mendez, Josefina; Mayan, Olga. "Evaluation of genetic damage in workers employed in a rubber tyres production utilizing the comet assay". 2006. 10.1016/J.TOXLET.2006.06.267
Conference paper	"The health impact of exposure to disinfection by products in indoor swimming pools – looking at immunological biomarkers". Paper presented in 38th International Winter-Workshop Clinical, Chemical and Biochemical Aspects of Pteridines and Related Topics, Innsbruck, 2019. Published Costa, Carla; Kiliç, Gozde; Brandão, Fátima; Bessa, Maria João; Costa, Solange; Pásaro, Eduardo; Valdiglesias, Vanessa; et al. "Cytotoxicity of iron oxide nanoparticles with different coatings on human neuronal cells". 2015. 10.1016/J.TOXLET.2014.06.673 Costa, Solange; Costa, Carla; García-Léston, Julia; Coelho, Patrícia; Silva, Susana; Carvalho, Sandra; Laffon, Blanca; et al. "Human exposure to formaldehyde, a risk evaluation of occupational health effects". 2014. 10.1016/J.TOXLET.2014.06.419 Costa, S.; Brandão, F.; Coelho, M.; Costa, C.; Coelho, P.; Silva, S.; Porto, B.; Teixeira, J.P.; Teixeira, J. P.. "Micronucleus frequencies in lymphocytes and buccal cells in formaldehyde exposed workers". 2013. 10.2495/EHR130081 Kiliç, Gözde; Costa, Carla; Teixeira, João Paulo; Pásaro, Eduardo; Valdiglesias, Vanessa; Laffon, Blanca; Kilic, Goezde; Teixeira, Joao Paulo; Pasaro, Eduardo. "Neurotoxicity assessment of zinc oxide nanoparticles: Cytotoxic and genotoxic effects". 2013. 10.1016/J.TOXLET.2013.05.600 Costa, S.; Coelho, P.; Costa, C.; Silva, S.; Coelho, M.; Porto, B.; Teixeira, J. P.. "Human biomonitoring of occupational exposure to formaldehyde". 2011. 10.1016/J.TOXLET.2011.05.276 Teixeira, João; Costa, Solange; Coelho, Patricia; Costa, Carla; Silva, Susana; Moreira, Ana; Laffon, Blanca; Teixeira, Joao. "Cytogenotoxic Effect on Workers Exposed to Styrene. Influence of Genetic Polymorphisms". 2011. 10.1097/01.EDE.0000392391.13418.78 Costa, C.; Silva, S. P.; Coelho, P. S.; Costa, S.; Snawder, J.; Teixeira, J. P.. "Micronuclei frequency of a pesticide exposed population". 2011. 10.1016/J.TOXLET.2011.05.151 Costa, C.; Silva, S.; Coelho, P.; Costa, S.; Neves, J.; Johnson, B.; Mayan, O.; Snawder, J.; Teixeira, J. P.. "Recent genetic damage in a pesticide-exposed population: Comet assay and micronuclei in reticulocytes". 2010. 10.1016/J.TOXLET.2010.03.1019 Laffon, Blanca; García-Lestón, Julia; Roma-Torres, Joana; Teixeira, Joao Paulo; Costa, Carla; Coelho, Patricia; Monteiro, Silvia; et al. "Effects of occupational exposure to lead: Flow cytometric study". 2009. 10.1016/J.TOXLET.2009.06.513 Teixeira, Joao; Coelho, Patricia; Silva, Susana; Costa, Carla; Roma-Torres, Joana; Santos, Luis; Gaspar, Jorge; Costa, Solange. "DNA damage in pathology staff occupationally exposed to formaldehyde". 2008. Costa, S.; Coelho, P.; Costa, C.; Silva, S.; Mayan, O.; Gaspar, J.; Rueff, J.; Tavares, A.; Teixeira, J. P.. "Genotoxic evaluation in pathology and anatomy laboratory workers exposed to formaldehyde". 2008. 10.1016/S1359-6349(08)71872-X
Conference poster	"Co-exposure with CeO2NPs results in an antagonistic effect on the cytotoxicity and genotoxicity of TiO2NP on A549 cells". Paper presented in Total-NanoSafe International Conference, 2021. "Salivary Leucocytes as Alternative Model to Study Nanomaterials Genotoxicity: the Case of ZnO and CeO2 Nanoparticles". Paper presented in Total-NanoSafe International Conference, 2021. "Prenatal exposure to tobacco smoke: H2AX phosphorylation levels in umbilical cord blood". Paper presented in 6th Croatian Congress of Toxicology, 2021. "Maternal tobacco smoke exposure and determination of the optimal urinary cotinine cut-off values: a cross-sectional birth study". Paper presented in 56th Congress of the European Societies of Toxicology, EUROTOX 2021, 2021. "Genotoxicity assessment of TiO2 nanoparticles in SH-SY5Y cells: suitability of the cytokinesis-block micronucleus test". Paper presented in COST Action CA17140 Nano2ClinicWorking Group 2 Online Conference “Characterisation of nanomaterials towards safe and efficient nanodrugs", 2021. "Histone H2AX phosphorylation: assessing the effect of cryopreservation and cell stimulation in DNA damage levels". Paper presented in Jornadas Ibéricas de Toxicologia, 2021. "Occupational dermal exposure to alcohol-based disinfectant products against COVID-19: a protocol for a systematic review". Paper presented in IFEH 4th World Academic Conference on Environmental Health, 2021. "Adequacy of the standardised in vitro mammalian cell Micronucleus (MN) test for nanomaterials genotoxicity testing". Paper presented in NanoTox 2021 Conference, 2021. "Primary and oxidative DNA damage induced by titanium dioxide nanoparticles in salivary leukocytes: a non-invasive alternative in nanomaterials genotoxicity assessment". Paper presented in NanoTox 2021 Conference, 2021. "Endocrine disrupting chemicals in indoor dust and the implications for human exposure: preliminary findings". Paper presented in MESAEP 2020 - 20th MESAEP International Symposium, 2020. "Genotoxicity study of human astrocytes exposed to oleic acid-coated iron oxide nanoparticles". Paper presented in International Nanoscience Student Conference - INASCON2020, 2020. "Assessment of genotoxic effects of titanium dioxide nanoparticles on different human cell types". Paper presented in . International Nanoscience Student Conference - INASCON2020, 2020. "A first insight into the genotoxicity induced on A549 human cell line by titanium and cerium dioxide nanoparticles co-exposed with arsenic and mercury". Paper presented in International Nanoscience Student Conference - INASCON2020, 2020. "Evaluation of DNA damage in the rat lung after inhalation exposure to TiO2 and SiO2 nanoparticles". Paper presented in 55th Congress of the European Societies of Toxicology (EUROTOX 2019), 2019. "Exposure to traffic-related air pollutants during physical exercise outdoors". Paper presented in ISES ISIAQ 2019, 2019. "Characterization of TiO2 and CeO2 engineered nanomaterials for cytotoxicity assessment at environmental relevant concentrations". Paper presented in RICI8 - 8th Iberian Meeting on Colloids and Interfaces, 2019. "Impact of tobacco use and environmental tobacco smoke exposure in perinatal outcomes in a Portuguese population". Paper presented in 15th IUTOX International Congress of Toxicology (ICTXV), 2019. "Assessment of DNA damage in the lung tissue of rats exposed by inhalation to TiO2 and SiO2 nanoparticles". Paper presented in 13th International Comet Assay Workshop (ICAW2019), 2019. "Maternal particulate air pollution exposure and DNA damage in umbilical cord blood". Paper presented in XIV Congresso da Associação Brasileira de Mutagênese e Genômica Ambiental, 2019. "Genotoxicity of trihalomethanes present in indoor swimming pools: a population targeted analysis". Paper presented in 47th Meeting of the European Environmental Mutagenesis and Genomics Society (EEMGS2019), 2019. "Cytotoxicity and DNA damage of a panel of manufactured nanomaterials in rat alveolar epithelial RLE-6TN cells". Paper presented in Multi-Functional Nano-Carbon Composite Materials (MultiComp) Meeting, 2019. "DNA Damage in Indoor Swimming Pools Users Analysed by Comet Assay". Paper presented in SOT 58th Annual Meeting and ToxExpo, 2019. "Cytotoxicity and DNA damage in rat alveolar epithelial RLE-6TN cells exposed to different variants of silica nanoparticles". Paper presented in 43rd Annual Conference of Environmental Mutagen Society of India (EMSI), 2019. Rosário, Fernanda; Bessa, Maria João; Brandão, Fátima; Costa, Carla; Lopes, Cláudia B.; Estrada, Ana C.; Tavares, Daniela S.; Teixeira, João Paulo; Reis, Ana Teresa. "Unravelling the Potential Cytotoxic Effects of Metal Oxide Nanoparticles and Metal(Loid) Mixtures on A549 Human Cell Line". 2018. 10.3390/nano10030447 Amaro, R. D. N.; Esteves, F. C.; Silva, S.; Costa, C.; Costa, S.; Teixeira, J. P.. "Genetic damage in young swimmers exposed to pool disinfection by-products". 2018. 10.1016/J.TOXLET.2018.06.808 Esteves, F. C.; Amaro, A.; Silva, S.; Costa, C.; Costa, S.; Teixeira, J. P.. "Human exposure to disinfection by-products in indoor swimming pools - looking at the genotoxic effects". 2018. 10.1016/J.TOXLET.2018.06.807 Silva, A. I.; Madureira, J.; Reis, A. T.; Lage, B.; Esteves, F. C.; Barbosa Junior, F.; Teixeira, J. P.; Costa, C.. "NEOGENE Project - Task I: Characterization of in utero exposure to environmental tobacco smoke: using cotinine as a biomarker". 2018. 10.1016/J.TOXLET.2018.06.567 Brandao, M. F. P.; Bessa, M. J.; Costa, C.; Fraga, S.; Haase, A.; Teixeira, J. P.. "Insights into the role of the physicochemical properties in the toxicity of SiO2 nanoparticles in rat alveolar epithelial RLE-6TN cells". 2018. 10.1016/J.TOXLET.2018.06.921 Menezes, Catarina; Mendes, Ana; Farcal, Lucian; Ziemann, Christina; Burla, Sabina; Creutzenberg, Otto; Costa, Carla; et al. "Cytotoxicity and genotoxicity of graphene-family nanomaterials in RAW 264.7 mouse macrophages". 2017. 10.1016/J.TOXLET.2017.07.534 Costa, Carla; Reis, Ana Teresa; Silva, Ana Ines; Tirsina, Alla; Barros, Sergio; Barbosa, Fernando, Jr.; Teixeira, Joao Paulo. "NEOGENE Project - Genetic and epigenetic effects of in utero exposure to tobacco smoke. Rationale and design". 2017. 10.1016/J.TOXLET.2017.07.335 Brandao, Fatima; Bessa, Maria Joao; Costa, Carla; Fraga, Sonia; Haase, Andrea; Teixeira, Joao Paulo. "Role of surface capping on the cytotoxicity of silica nanoparticles in rat alveolar epithelial cells". 2017. 10.1016/J.TOXLET.2017.07.526 Tirsina, A.; Costa, C.; Costa, S.; Teixeira, J. P.. "The influence of washing methods on the DNA damage levels assessed by Comet assay". 2016. 10.1016/J.TOXLET.2016.07.439 Alves, A. C.; Costa, C.; Tirsina, A.; Monteiro, M. S.; Soares, A. M.; Loureiro, S.; Teixeira, J. P.. "Genotoxic effect of transplacental exposure to tobacco smoke". 2016. 10.1016/J.TOXLET.2016.06.1767 Costa, C.; Brandao, F.; Bessa, M. J.; Costa, S.; Valdiglesias, V.; Kilic, G.; Fernandez-Bertolez, N.; et al. "In vitro toxicity screening of silica-coated superparamagnetic iron oxide nanoparticles in glial cells". 2015. 10.1016/J.TOXLET.2015.08.638 Sanchez-Flores, M.; Kilic, G.; Costa, C.; Fernandez-Bertolez, N.; Costa, S.; Teixeira, J. P.; Pasaro, E.; Valdiglesias, V.; Laffon, B.. "Silica-coated iron oxide nanoparticles do not induce DNA double strand breaks or aneugenicity in SHSY5Y neuronal cells". 2015. 10.1016/J.TOXLET.2015.08.593 Kilic, G.; Costa, C.; Fernandez-Bertolez, N.; Costa, S.; Paulo Teixeira, Joao; Pasaro, E.; Laffon, B.; Park, M. Vdz; Valdiglesias, V.. "Oxidative stress induced by silica-coated iron oxide nanoparticles in SHSY5Y neuronal cells". 2015. 10.1016/J.TOXLET.2015.08.601 Costa, Carla. "Effects of mercury and tobacco smoke prenatal exposure in newborns from Aveiro region, Portugal". 2015. 10.1016/J.TOXLET.2015.08.389 Costa, S.; Costa, C.; Silva, S.; Carvalho, J.; Laffon, B.; Teixeira, J.. "A molecular approach to frailty in older adults". 2015. 10.1016/J.TOXLET.2015.08.361 Costa, Carla. "Prenatal exposure to environmental tobacco smoke, genetic damage and DNA methylation". 2015. 10.1016/J.TOXLET.2015.08.1081 Costa, Solange; Costa, Carla; Silva, Susana; Coelho, Patricia; Porto, Beatriz; Teixeira, Joao Paulo; Coelho, Patrícia; Teixeira, João Paulo. "Cytogenetic alterations in formaldehyde exposed workers measured in a target and distal tissue". 2013. 10.1016/J.TOXLET.2013.05.029
Journal article	Carlos Carvalhais; Ricardo Dias; Carla Costa; Manuela V. Silva. "General Knowledge and Attitudes about Safety and Emergency Evacuation: The Case of a Higher Education Institution". Safety (2023): https://doi.org/10.3390/safety10010003. 10.3390/safety10010003 Klebson Silva Santos; Carla Costa; Maria João Bessa; João Paulo Teixeira; Ana Veruska Cruz da Silva Muniz; Francine Ferreira Padilha; Cláudio Dariva; Maria Beatriz Pinto Prior Oliveira. "Azadirachta indica A. Juss (neem) phenolic extract inhibits human B-lymphoblastoid cells growth via cell cycle arrest, apoptosis induction, and DNA damage". Exploration of Foods and Foodomics (2023): https://doi.org/10.37349/eff.2023.00011. 10.37349/eff.2023.00011 Fátima Brandão; Carla Costa; Maria João Bessa; Vanessa Valdiglesias; Bryan Hellack; Andrea Haase; Sónia Fraga; João Paulo Teixeira. "Multiparametric in vitro genotoxicity assessment of different variants of amorphous silica nanomaterials in rat alveolar epithelial cells". Nanotoxicology (2023): https://doi.org/10.1080/17435390.2023.2265481. 10.1080/17435390.2023.2265481 Ana Teresa Reis; Carla Costa; Sónia Fraga. "Editorial of Special Issue: The Toxicity of Nanomaterials and Legacy Contaminants: Risks to the Environment and Human Health". International Journal of Molecular Sciences (2023): https://doi.org/10.3390/ijms241411723. 10.3390/ijms241411723 Møller, Peter; Azqueta, Amaya; Rodriguez-Garraus, Adriana; Bakuradze, Tamara; Richling, Elke; Bankoglu, Ezgi Eyluel; Stopper, Helga; et al. "DNA strand break levels in cryopreserved mononuclear blood cell lines measured by the alkaline comet assay: results from the hCOMET ring trial". Mutagenesis 38 5 (2023): 273-282. http://dx.doi.org/10.1093/mutage/gead019. 10.1093/mutage/gead019 Møller, Peter; Azqueta, Amaya; Rodriguez-Garraus, Adriana; Bakuradze, Tamara; Richling, Elke; Bankoglu, Ezgi Eyluel; Stopper, Helga; et al. "Long-term cryopreservation of potassium bromate positive assay controls for measurement of oxidatively damaged DNA by the Fpg-modified comet assay: results from the hCOMET ring trial". Mutagenesis 38 5 (2023): 264-272. http://dx.doi.org/10.1093/mutage/gead020. 10.1093/mutage/gead020 Zare Jeddi, Maryam; Galea, Karen S.; Viegas, Susana; Fantke, Peter; Louro, Henriqueta; Theunis, Jan; Govarts, Eva; et al. "FAIR environmental and health registry (FAIREHR)- supporting the science to policy interface and life science research, development and innovation". Frontiers in Toxicology 5 (2023): http://dx.doi.org/10.3389/ftox.2023.1116707. 10.3389/ftox.2023.1116707 Møller, Peter; Azqueta, Amaya; Sanz-Serrano, Julen; Bakuradze, Tamara; Richling, Elke; Eyluel Bankoglu, Ezgi; Stopper, Helga; et al. "Visual comet scoring revisited: a guide to scoring comet assay slides and obtaining reliable results". Mutagenesis 38 5 (2023): 253-263. http://dx.doi.org/10.1093/mutage/gead015. 10.1093/mutage/gead015 Møller, Peter; Azqueta, Amaya; Collia, Miguel; Bakuradze, Tamara; Richling, Elke; Bankoglu, Ezgi Eyluel; Stopper, Helga; et al. "Inter-laboratory variation in measurement of DNA damage by the alkaline comet assay in the hCOMET ring trial". Mutagenesis 38 5 (2023): 283-294. http://dx.doi.org/10.1093/mutage/gead014. 10.1093/mutage/gead014 Rosária Seabra; Fernanda Malhão; Alexandra Correia; Carla Costa; Anake Kijjoa; Eduardo Rocha. "Effects and Mechanisms of Action of Preussin, a Marine Fungal Metabolite, against the Triple-Negative Breast Cancer Cell Line, MDA-MB-231, in 2D and 3D Cultures". Marine Drugs (2023): https://doi.org/10.3390/md21030166. 10.3390/md21030166 Collins, Andrew; Møller, Peter; Gajski, Goran; Vodenková, Sona; Abdulwahed, Abdulhadi; Anderson, Diana; Bankoglu, Ezgi Eyluel; et al. "Measuring DNA modifications with the comet assay: a compendium of protocols". Nature Protocols 18 3 (2023): 929-989. http://dx.doi.org/10.1038/s41596-022-00754-y. 10.1038/s41596-022-00754-y Lorenzo-López, Laura; Lema-Arranz, Carlota; Fernández-Bertólez, Natalia; Costa, Solange; Costa, Carla; Teixeira, João Paulo; Pásaro, Eduardo; Valdiglesias, Vanessa; Laffon, Blanca. "Relationship between DNA damage measured by the comet-assay and cognitive function". Mutation Research/Genetic Toxicology and Environmental Mutagenesis 883-884 (2022): 503557. http://dx.doi.org/10.1016/j.mrgentox.2022.503557. 10.1016/j.mrgentox.2022.503557 Costa, Carla; Assunção, Ricardo; Sequeira, Diana; Esteves, Filipa; Valdiglesias, Vanessa; Laffon, Blanca; Teixeira, João Paulo; Madureira, Joana. "From trihalomethanes chronic daily intake through multiple exposure routes to cancer and non-cancer health risk assessment: Evidence from public Portuguese indoor swimming pools facilities using a probabilistic approach". Science of The Total Environment 818 (2022): 151790. http://dx.doi.org/10.1016/j.scitotenv.2021.151790. 10.1016/j.scitotenv.2021.151790 Rosário, Fernanda; Costa, Carla; Lopes, Cláudia B.; Estrada, Ana C.; Tavares, Daniela S.; Pereira, Eduarda; Teixeira, João Paulo; Reis, Ana Teresa. "In Vitro Hepatotoxic and Neurotoxic Effects of Titanium and Cerium Dioxide Nanoparticles, Arsenic and Mercury Co-Exposure". International Journal of Molecular Sciences 23 5 (2022): 2737. http://dx.doi.org/10.3390/ijms23052737. 10.3390/ijms23052737 Ana Inês Silva; Alexandra Camelo; Joana Madureira; Ana Teresa Reis; Ana Paula Machado; João Paulo Teixeira; Carla Costa. "Urinary cotinine assessment of maternal smoking and environmental tobacco smoke exposure status and its associations with perinatal outcomes: a cross-sectional birth study". Environmental Research 203 (2022): 111827-111827. https://doi.org/10.1016/j.envres.2021.111827. 10.1016/j.envres.2021.111827 Teixeira-Gomes, Armanda; Laffon, Blanca; Valdiglesias, Vanessa; Gostner, Johanna M.; Felder, Thomas; Costa, Carla; Madureira, Joana; et al. "Exploring Early Detection of Frailty Syndrome in Older Adults: Evaluation of Oxi-Immune Markers, Clinical Parameters and Modifiable Risk Factors". Antioxidants 10 12 (2021): 1975. http://dx.doi.org/10.3390/antiox10121975. 10.3390/antiox10121975 "DNA damage in circulating leukocytes measured with the comet assay may predict the risk of death". Scientific Reports 11 1 (2021): http://dx.doi.org/10.1038/s41598-021-95976-7. 10.1038/s41598-021-95976-7 "Suitability of the In Vitro Cytokinesis-Block Micronucleus Test for Genotoxicity Assessment of TiO2 Nanoparticles on SH-SY5Y Cells". International Journal of Molecular Sciences 22 16 (2021): 8558-8558. http://dx.doi.org/10.3390/ijms22168558. 10.3390/ijms22168558 "Salivary Leucocytes as In Vitro Model to Evaluate Nanoparticle-Induced DNA Damage". Nanomaterials 11 8 (2021): 1930-1930. http://dx.doi.org/10.3390/nano11081930. 10.3390/nano11081930 "Fucoxanthin Holds Potential to Become a Drug Adjuvant in Breast Cancer Treatment: Evidence from 2D and 3D Cell Cultures". Molecules 26 14 (2021): 4288-4288. http://dx.doi.org/10.3390/molecules26144288. 10.3390/molecules26144288 "How can exposure to engineered nanomaterials influence our epigenetic code? A review of the mechanisms and molecular targets". Mutation Research/Reviews in Mutation Research 788 (2021): 108385-108385. http://dx.doi.org/10.1016/j.mrrev.2021.108385. 10.1016/j.mrrev.2021.108385 "Insights into corrosion behaviour of uncoated Mg alloys for biomedical applications in different aqueous media". Journal of Materials Research and Technology 13 (2021): 1908-1922. http://dx.doi.org/10.1016/j.jmrt.2021.05.090. 10.1016/j.jmrt.2021.05.090 Fátima Brandão; Carla Costa; Maria João Bessa; Elise Dumortier; Florence Debacq-Chainiaux; Roland Hubaux; Michel Salmon; et al. "Genotoxicity and Gene Expression in the Rat Lung Tissue following Instillation and Inhalation of Different Variants of Amorphous Silica Nanomaterials (aSiO2 NM)". Nanomaterials 11 6 (2021): 1502-1502. https://doi.org/10.3390/nano11061502. 10.3390/nano11061502 "The hCOMET project: International database comparison of results with the comet assay in human biomonitoring. Baseline frequency of DNA damage and effect of main confounders". Mutation Research/Reviews in Mutation Research 787 (2021): 108371-108371. http://dx.doi.org/10.1016/j.mrrev.2021.108371. 10.1016/j.mrrev.2021.108371 Augusto, Sofia; Ratola, Nuno; Tarín-Carrasco, Patricia; Jiménez-Guerrero, Pedro; Turco, Marco; Schuhmacher, Marta; Costa, Solange; Teixeira, J.P.; Costa, Carla. "Population exposure to particulate-matter and related mortality due to the Portuguese wildfires in October 2017 driven by storm Ophelia". Environment International 144 (2020): 106056. http://dx.doi.org/10.1016/j.envint.2020.106056. 10.1016/j.envint.2020.106056 Esteves, Filipa; Amaro, Raquel; Silva, Susana; Sánchez-Flores, María; Teixeira, João Paulo; Costa, Carla. "The impact of comet assay data normalization in human biomonitoring studies outcomes". Toxicology Letters 332 (2020): 56-64. http://dx.doi.org/10.1016/j.toxlet.2020.06.024. 10.1016/j.toxlet.2020.06.024 Madureira, Joana; Camelo, Alexandra; Silva, Ana Inês; Reis, Ana Teresa; Esteves, Filipa; Ribeiro, Ana Isabel; Teixeira, João Paulo; Costa, Carla. "The importance of socioeconomic position in smoking, cessation and environmental tobacco smoke exposure during pregnancy". Scientific Reports 10 1 (2020): http://dx.doi.org/10.1038/s41598-020-72298-8. 10.1038/s41598-020-72298-8 "Assessment of indoor air exposure among newborns and their mothers: Levels and sources of PM10, PM2.5 and ultrafine particles at 65 home environments". Environmental Pollution 264 (2020): 114746-114746. http://dx.doi.org/10.1016/j.envpol.2020.114746. 10.1016/j.envpol.2020.114746 Joana Madureira; Klara Slezakova; Ana Inês Silva; Bruna Lage; Ana Mendes; Lívia Aguiar; Maria Carmo Pereira; João Paulo Teixeira; Carla Costa. "Assessment of indoor air exposure at residential homes: Inhalation dose and lung deposition of PM10, PM2.5 and ultrafine particles among newborn children and their mothers". Science of The Total Environment 717 (2020): 137293-137293. https://doi.org/10.1016/j.scitotenv.2020.137293. 10.1016/j.scitotenv.2020.137293 Møller, Peter; Muruzabal, Damian; Bakuradze, Tamara; Richling, Elke; Bankoglu, Ezgi Eyluel; Stopper, Helga; Langie, Sabine A S; et al. "Potassium bromate as positive assay control for the Fpg-modified comet assay". Mutagenesis 35 4 (2020): 341-348. http://dx.doi.org/10.1093/mutage/geaa011. 10.1093/mutage/geaa011 Brandão, Fátima; Fernández-Bertólez, Natalia; Rosário, Fernanda; Bessa, Maria João; Fraga, Sónia; Pásaro, Eduardo; Teixeira, João Paulo; et al. "Genotoxicity of TiO2 Nanoparticles in Four Different Human Cell Lines (A549, HEPG2, A172 and SH-SY5Y)". Nanomaterials 10 3 (2020): 412. http://dx.doi.org/10.3390/nano10030412. 10.3390/nano10030412 Costa, Solange; Costa, Carla; Madureira, Joana; Valdiglesias, Vanessa; Teixeira-Gomes, Armanda; Guedes de Pinho, Paula; Laffon, Blanca; Teixeira, João Paulo. "Occupational exposure to formaldehyde and early biomarkers of cancer risk, immunotoxicity and susceptibility". Environmental Research 179 (2019): 108740. http://dx.doi.org/10.1016/j.envres.2019.108740. 10.1016/j.envres.2019.108740 Madureira, Joana; Brancher, Emerson Antonio; Costa, Carla; Aurino de Pinho, Ricardo; Teixeira, João Paulo. "Cardio-respiratory health effects of exposure to traffic-related air pollutants while exercising outdoors: A systematic review". Environmental Research 178 (2019): 108647. http://dx.doi.org/10.1016/j.envres.2019.108647. 10.1016/j.envres.2019.108647 Maria João Bessa; Fátima Brandão; Micaela Machado Querido; Carla Costa; Cristiana Costa Pereira; Vanessa Valdiglesias; Blanca Laffon; et al. "Optimization of the harvesting and freezing conditions of human cell lines for DNA damage analysis by the alkaline comet assay". Mutation Research/Genetic Toxicology and Environmental Mutagenesis 845 (2019): 402994-402994. https://doi.org/10.1016/j.mrgentox.2018.12.002. 10.1016/j.mrgentox.2018.12.002 Natalia Fernández-Bertólez; Carla Costa; Maria João Bessa; Margriet Park; Marie Carriere; Fanny Dussert; João Paulo Teixeira; et al. "Assessment of oxidative damage induced by iron oxide nanoparticles on different nervous system cells". Mutation Research/Genetic Toxicology and Environmental Mutagenesis 845 (2019): 402989-402989. https://doi.org/10.1016/j.mrgentox.2018.11.013. 10.1016/j.mrgentox.2018.11.013 Fernández-Bertólez, Natalia; Costa, Carla; Brandão, Fátima; Duarte, José Alberto; Teixeira, Joao Paulo; Pásaro, Eduardo; Valdiglesias, Vanessa; Laffon, Blanca. "Evaluation of cytotoxicity and genotoxicity induced by oleic acid-coated iron oxide nanoparticles in human astrocytes". Environmental and Molecular Mutagenesis 60 9 (2019): 816-829. http://dx.doi.org/10.1002/em.22323. 10.1002/em.22323 Madureira, Joana; Costa, Solange; Teixeira, João Paulo; Costa, Carla. "Spotlight on the future of environmental and occupational health research". Journal of Toxicology and Environmental Health, Part A 82 9 (2019): 525-525. http://dx.doi.org/10.1080/15287394.2019.1634374. 10.1080/15287394.2019.1634374 Fernández-Bertólez, N.; Costa, C.; Brandão, F.; Kiliç, G.; Teixeira, J. P.; Pásaro, E.; Laffon, B.; Valdiglesias, V.. "Neurotoxicity assessment of oleic acid-coated iron oxide nanoparticles in SH-SY5Y cells". Toxicology 406-407 (2018): 81-91. https://www.ncbi.nlm.nih.gov/pubmed/29885472. 10.1016/j.tox.2018.06.003 Silva, D.; Moreira, R.; Sokhatska, O.; Beltrão, M.; Montanha, T.; Garcia-Larsen, V.; Villegas, R.; et al. "Meal-exercise challenge and physical activity reduction impact on immunity and inflammation (MERIIT trial)". Contemp Clin Trials Commun 10 (2018): 177-189. https://www.ncbi.nlm.nih.gov/pubmed/30009276. 10.1016/j.conctc.2018.05.010 Fernández-Bertólez, N.; Costa, C.; Brandão, F.; Kiliç, G.; Duarte, J. A.; Teixeira, J. P.; Pásaro, E.; Valdiglesias, V.; Laffon, B.. "Toxicological assessment of silica-coated iron oxide nanoparticles in human astrocytes". Food Chem Toxicol 118 (2018): 13-23. https://www.ncbi.nlm.nih.gov/pubmed/29709612. 10.1016/j.fct.2018.04.058 Abreu, A.; Costa, C.; Pinho E Silva, S.; Morais, S.; do Carmo Pereira, M.; Fernandes, A.; Moraes de Andrade, V.; Teixeira, J. P.; Costa, S.. "Wood smoke exposure of Portuguese wildland firefighters: DNA and oxidative damage evaluation". J Toxicol Environ Health A 80 13-15 (2017): 596-604. https://www.ncbi.nlm.nih.gov/pubmed/28524757. 10.1080/15287394.2017.1286896 Mendes, A. S.; Costa, C.; Costa, S.; Pereira, C.; Fraga, S.; Barbosa, F.; Teixeira, J. P.. "Recent developments on occupational and environmental toxicology". J Toxicol Environ Health A 80 13-15 (2017): 595-595. https://www.ncbi.nlm.nih.gov/pubmed/28968178. 10.1080/15287394.2017.1382124 Laffon, B.; Fernández-Bertólez, N.; Costa, C.; Pásaro, E.; Valdiglesias, V.. "Comparative study of human neuronal and glial cell sensitivity for in vitro neurogenotoxicity testing". Food Chem Toxicol 102 (2017): 120-128. https://www.ncbi.nlm.nih.gov/pubmed/28174116. 10.1016/j.fct.2017.02.005 Bessa, M. J.; Costa, C.; Reinosa, J.; Pereira, C.; Fraga, S.; Fernández, J.; Bañares, M. A.; Teixeira, J. P.. "Moving into advanced nanomaterials. Toxicity of rutile TiO". Toxicol Appl Pharmacol 316 (2017): 114-122. https://www.ncbi.nlm.nih.gov/pubmed/28039000. 10.1016/j.taap.2016.12.018 Bessada, S. M. F.; Barreira, J. C. M.; Santos, J.; Costa, C.; Pimentel, F. B.; Bessa, M. J.; Teixeira, J. P.; Oliveira, M. B. P.P. "Evaluation of the cytotoxicity (HepG2) and chemical composition of polar extracts from the ruderal species Coleostephus myconis (L.) Rchb.f". J Toxicol Environ Health A 80 13-15 (2017): 641-650. https://www.ncbi.nlm.nih.gov/pubmed/28524760. 10.1080/15287394.2017.1286915 Esteves, F.; Teixeira, E.; Amorim, T.; Costa, C.; Pereira, C.; Fraga, S.; De Andrade, V. M.; Teixeira, J. P.; Costa, S.. "Assessment of DNA damage in a group of professional dancers during a 10-month dancing season". J Toxicol Environ Health A 80 13-15 (2017): 797-804. https://www.ncbi.nlm.nih.gov/pubmed/28696896. 10.1080/15287394.2017.1331599 Soares-Miranda, Luisa; Abreu, Sandra; Silva, Marco; Peixoto, Armando; Ramalho, Rosa; da Silva, Pedro Correia; Costa, Carla; et al. "Cancer Survivor Study (CASUS) on colorectal patients: longitudinal study on physical activity, fitness, nutrition, and its influences on quality of life, disease recurrence, and survival. Rationale and design". International Journal of Colorectal Disease (2017): 1-7. https://publons.com/wos-op/publon/12751655/. 10.1007/S00384-016-2671-X Soto-Zarazúa, María G.; Bah, Moustapha; García-Alcocer, María G.; Berumen, Laura C.; Costa, Carla Sofia; Bessa, Maria João; Rodrigues, Francisca; et al. "Assessment of Beneficial and Possible Toxic Effects of Two New Alfalfa-Derived Shelf Products". Journal of Medicinal Food 19 10 (2016): 970-977. https://publons.com/wos-op/publon/10635174/. 10.1089/JMF.2016.0024 Costa, Solange; Ceppi, Marcello; Costa, Carla; Silva, Susana; Pereira, Cristiana; Laffon, Blanca; Bonassi, Stefano; Teixeira, João Paulo; Teixeira, Joao Paulo. "The cytokinesis-block micronucleus (CBMN) assay in human populations exposed to styrene: a systematic review and meta-analysis". Mutation Research/Reviews in Mutation Research (2016): https://publons.com/wos-op/publon/10568575/. 10.1016/J.MRREV.2016.06.003 "Efectos celulares y moleculares de nanopartículas de magnetita en células neuronales humanas (In Spanish)". Real Academia Gallega de Ciencias 35 (2016): 65-103. https://dialnet.unirioja.es/servlet/articulo?codigo=7057420#. Published Pereira, Cristiana; Coelho, Rosa; Gracio, Daniela; Dias, Claudia; Silva, Marco; Peixoto, Armando; Lopes, Pedro; et al. "DNA Damage and Oxidative DNA Damage in Inflammatory Bowel Disease". Journal of Crohn's and Colitis (2016): jjw088-jjw088. https://publons.com/wos-op/publon/10568576/. 10.1093/ECCO-JCC/JJW088 Kilic, Gozde; Costa, Carla; Fernandez-Bertolez, Natalia; Pasaro, Eduardo; Teixeira, Joao Paulo; Laffon, Blanca; Valdiglesias, Vanessa. "In vitro toxicity evaluation of silica-coated iron oxide nanoparticles in human SHSY5Y neuronal cells (vol 5, pg 235, 2016)". Toxicology Research (2016): https://publons.com/wos-op/publon/8430955/. 10.1039/C6TX90013E Valdiglesias, Vanessa; Fernandez-Bertolez, Natalia; Kilic, Gozde; Costa, Carla; Costa, Solange; Fraga, Sonia; Bessa, Maria Joao; et al. "Are iron oxide nanoparticles safe? Current knowledge and future perspectives". Journal of Trace Elements in Medicine and Biology (2016): https://publons.com/wos-op/publon/8430956/. 10.1016/J.JTEMB.2016.03.017 Costa, Carla; Brandão, Fátima; Bessa, Maria João; Costa, Solange; Valdiglesias, Vanessa; Kiliç, Gözde; Fernández-Bertólez, Natalia; et al. "In vitro cytotoxicity of superparamagnetic iron oxide nanoparticles on neuronal and glial cells. Evaluation of nanoparticle interference with viability tests". Journal of Applied Toxicology 36 3 (2015): n/a-n/a. http://dx.doi.org/10.1002/jat.3213. 10.1002/jat.3213 Costa, Solange; Carvalho, Sandra; Costa, Carla; Coelho, Patricia; Silva, Susana; Santos, Luis S.; Gaspar, Jorge F.; et al. "Increased levels of chromosomal aberrations and DNA damage in a group of workers exposed to formaldehyde". Mutagenesis 30 4 (2015): 463-473. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000357885900002&KeyUID=WOS:000357885900002. 10.1093/mutage/gev002 Valdiglesias, Vanessa; Kilic, Goezde; Costa, Carla; Fernandez-Bertolez, Natalia; Pasaro, Eduardo; Teixeira, Joao Paulo; Laffon, Blanca. "Effects of Iron Oxide Nanoparticles: Cytotoxicity, Genotoxicity, Developmental Toxicity, and Neurotoxicity". Environmental and Molecular Mutagenesis 56 2 (2015): 125-148. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000350356800005&KeyUID=WOS:000350356800005. 10.1002/em.21909 "Modeling of human exposure to benzene in urban environments.". Journal of toxicology and environmental health. Part A (2014): https://doi.org/10.1080/15287394.2014.909299. 10.1080/15287394.2014.909299 Costa, Solange; Ferreira, Joana; Silveira, Carlos; Costa, Carla; Lopes, Diogo; Relvas, Helder; Borrego, Carlos; et al. "Integrating Health on Air Quality Assessment-Review Report on Health Risks of Two Major European Outdoor Air Pollutants: PM and NO2". Journal of Toxicology and Environmental Health-Part B-Critical Reviews 17 6 (2014): 307-340. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000343310600001&KeyUID=WOS:000343310600001. 10.1080/10937404.2014.946164 Costa, C.; García-Lestón, J.; Costa, S.; Coelho, P.; Silva, S.; Pingarilho, M.; Valdiglesias, V.; et al. "Is organic farming safer to farmers' health? A comparison between organic and traditional farming". Toxicology Letters (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84896410925&partnerID=MN8TOARS. 10.1016/j.toxlet.2014.02.011 Botelho, M.C.; Costa, C.; Silva, S.; Costa, S.; Dhawan, A.; Oliveira, P.A.; Teixeira, J.P.. "Effects of titanium dioxide nanoparticles in human gastric epithelial cells in vitro". Biomedicine and Pharmacotherapy 68 1 (2014): 59-64. http://www.scopus.com/inward/record.url?eid=2-s2.0-84895071777&partnerID=MN8TOARS. 10.1016/j.biopha.2013.08.006 Coelho, P.; García-Lestón, J.; Costa, S.; Costa, C.; Silva, S.; Fuchs, D.; Geisler, S.; et al. "Immunological alterations in individuals exposed to metal(loid)s in the Panasqueira mining area, Central Portugal". Science of the Total Environment 475 (2014): 1-7. http://www.scopus.com/inward/record.url?eid=2-s2.0-84892163685&partnerID=MN8TOARS. 10.1016/j.scitotenv.2013.12.093 Costa, Carla. "_Avaliação in vitro da neurotoxicidade de nanopartículas de magnetite revestidas por sílica". especial 4 (2014): 42-42. "Avaliação de dano genético em agricultores: agricultura biológica e tradicional. (In Portuguese)". Observações - Boletim Epidemiológico 3 4 (2014): 36-38. http://hdl.handle.net/10400.18/2545. Published Laffon, Blanca; Iglesias, Vanessa; Costa, Carla; Costa, Solange; Teixeira, João Paulo; Mendez, Josefina. "Daño al sistema nervioso inducido por nanopartículas: toxicidad celular inducida por nanopartículas de óxidos metálicos en células neuronales humanas". (2013): Costa, S.; García-Lestón, J.; Coelho, M.; Coelho, P.; Costa, C.; Silva, S.; Porto, B.; Laffon, B.; Teixeira, J. P.. "Cytogenetic and immunological effects of formaldehyde in a group of exposed workers". (2013): Coelho, P.; Costa, S.; Costa, C.; Silva, S.; Walter, A.; Ranville, J.; Pastorinho, M.R.; et al. "Biomonitoring of several toxic metal(loid)s in different biological matrices from environmentally and occupationally exposed populations from Panasqueira mine area, Portugal". Environmental Geochemistry and Health (2013): 1-15. http://www.scopus.com/inward/record.url?eid=2-s2.0-84882769361&partnerID=MN8TOARS. 10.1007/s10653-013-9562-7 Valdiglesias, V.; Costa, C.; Sharma, V.; Kiliç, G.; Pásaro, E.; Teixeira, J.P.; Dhawan, A.; Laffon, B.. "Comparative study on effects of two different types of titanium dioxide nanoparticles on human neuronal cells". Food and Chemical Toxicology 57 (2013): 352-361. http://www.scopus.com/inward/record.url?eid=2-s2.0-84877322512&partnerID=MN8TOARS. 10.1016/j.fct.2013.04.010 Coelho, P.; García-Lestón, J.; Costa, S.; Costa, C.; Silva, S.; Dall'Armi, V.; Zoffoli, R.; et al. "Genotoxic effect of exposure to metal(loid)s. A molecular epidemiology survey of populations living and working in Panasqueira mine area, Portugal". Environment International 60 (2013): 163-170. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884146116&partnerID=MN8TOARS. 10.1016/j.envint.2013.08.014 Valdiglesias, V.; Costa, C.; Kiliç, G.; Costa, S.; Pásaro, E.; Laffon, B.; Teixeira, J.P.. "Neuronal cytotoxicity and genotoxicity induced by zinc oxide nanoparticles". Environment International 55 (2013): 92-100. http://www.scopus.com/inward/record.url?eid=2-s2.0-84875611485&partnerID=MN8TOARS. 10.1016/j.envint.2013.02.013 Costa, S.; García-Lestón, J.; Coelho, M.; Coelho, P.; Costa, C.; Silva, S.; Porto, B.; Laffon, B.; Teixeira, J.P.. "Cytogenetic and immunological effects associated with occupational formaldehyde exposure". Journal of Toxicology and Environmental Health - Part A: Current Issues 76 4-5 (2013): 217-229. http://www.scopus.com/inward/record.url?eid=2-s2.0-84876149455&partnerID=MN8TOARS. 10.1080/15287394.2013.757212 Costa, Carla; Teixeira, João Paulo. "Genotoxic effects of pesticides". Revista de Ciências Agrárias 35 2 (2012): 19-31. Costa, C.; Costa, S.; Silva, S.; Coelho, P.; Botelho, M.; Gaspar, J.; Rueff, J.; Laffon, B.; Teixeira, J.P.. "DNA damage and susceptibility assessment in industrial workers exposed to styrene". Journal of Toxicology and Environmental Health - Part A: Current Issues 75 13-15 (2012): 735-746. http://www.scopus.com/inward/record.url?eid=2-s2.0-84864038381&partnerID=MN8TOARS. 10.1080/15287394.2012.688488 Valdiglesias, V.; Fernández-Tajes, J.; Costa, C.; Méndez, J.; Pásaro, E.; Laffon, B.. "Alterations in metabolism-related genes induced in SHSY5Y cells by okadaic acid exposure". Journal of Toxicology and Environmental Health - Part A: Current Issues 75 13-15 (2012): 844-856. http://www.scopus.com/inward/record.url?eid=2-s2.0-84864070029&partnerID=MN8TOARS. 10.1080/15287394.2012.690703 Valdiglesias, V.; Kiliç, G.; Costa, C.; Amor-Carro, Ó.; Mariñas-Pardo, L.; Ramos-Barbón, D.; Méndez, J.; Pásaro, E.; Laffon, B.. "In vivo genotoxicity assessment in rats exposed to prestige-like oil by inhalation". Journal of Toxicology and Environmental Health - Part A: Current Issues 75 13-15 (2012): 756-764. http://www.scopus.com/inward/record.url?eid=2-s2.0-84864062359&partnerID=MN8TOARS. 10.1080/15287394.2012.689801 Ferreira, S.A.; Carvalho, V.; Costa, C.; Teixeira, J.P.; Vilanova, M.; Gama, F.M.. "Self-assembled mannan nanogel: Cytocompatibility and cell localization". Journal of Biomedical Nanotechnology 8 3 (2012): 473-481. http://www.scopus.com/inward/record.url?eid=2-s2.0-84862300558&partnerID=MN8TOARS. 10.1166/jbn.2012.1408 Coelho, P.; Costa, S.; Silva, S.; Walter, A.; Ranville, J.; Sousa, A.C.A.; Costa, C.; et al. "Metal(Loid) levels in biological matrices from human populations exposed to mining contamination-panasqueira mine (Portugal)". 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Intellectual property

Patent

2017. "Product derived from the leaves of azadirachta indica with antiproliferative effect against human lymphoblastic cells".

Award

2023	Best Scientific Publication Region Galicia North of Portugal
2022	Best Scientific Publication Region Galicia ¿ North of Portugal IACOBUS, Spain
2021	Best Scientific Publication Region Galicia – North of Portugal IACOBUS, Spain
2020	Best Scientific Publication Region Galicia – North of Portugal IACOBUS, Spain
2019	Best Scientific Publication Region Galicia – North of Portugal IACOBUS, Spain
2011	Best oral communication in ICOEH, 2011
2005	Prémio Prevenir Mais, Viver Melhor no Trabalho 2004 1ºPrize Investigation Projects
2004	2º prize for Best Oral Communication in the 5th National Meeting of Occupational Heath

Other distinction

2014	Grant Full Fellowship for participation in the 7th International Nanotoxicology Congress
2011	Grant to participate in the training school Impact Assessment of Nanomaterials in vitro and in vivo testing strategies
2011	Grant to participate in EUROTOX 2011
2008	Grant for Health risk assessment I: Principles and applications, 14-18 Abril, Stockholm, Sweden