Curriculum Vitae
Abel Martin Gonzalez Oliva
Identification
Personal identification
- Full name
- Abel Martin Gonzalez Oliva
Citation names
- Oliva, Abel
- Gonzalez Oliva, Abel
- Oliva, A.G.
- Abel Martin Gonzalez Oliva
Author identifiers
- Ciência ID
- 431C-8CE1-B7EE
- ORCID iD
- 0000-0001-8320-0937
- Researcher Id
- B-9118-2011
- Scopus Author Id
- 56254239700
Websites
- https://www.itqb.unl.pt/research/technology/biomolecular-diagnostics (Professional)
- https://www.itqb.unl.pt/labs/biomolecular-diagnostic (Professional)
Knowledge fields
- Agrarian Sciences - Agrarian and Food Biotechnology - Agricultural Biotechnology and Food Biotechnology
- Engineering and Technology - Medical Engineering
- Natural sciences - Biological Sciences - Other Biological Topics
Languages
| Language | Speaking | Reading | Writing | Listening | Peer-review |
|---|---|---|---|---|---|
| Spanish; Castilian (Mother tongue) | |||||
| Portuguese | Proficiency (C2) | Proficiency (C2) | Proficiency (C2) | Proficiency (C2) | Proficiency (C2) |
| German | Advanced (C1) | Advanced (C1) | Advanced (C1) | Advanced (C1) | Upper intermediate (B2) |
| English | Upper intermediate (B2) | Upper intermediate (B2) | Upper intermediate (B2) | Upper intermediate (B2) | Upper intermediate (B2) |
Education
| Degree | Classification | |
|---|---|---|
|
1986/06/01 - 1989/03/01
Concluded
|
Agrartechnik (Doktor (PhD))
Major in landwirtschaft wissenschaft
Universität Hohenheim Fakultät Agrarwissenschaften, Germany
"Einfluss Verschiedener Parameter auf die Trenneigenschaften des Planetentrommel-sortierers bei der Korn-Spreu-Trennung" (THESIS/DISSERTATION)
|
cum laude |
|
1984/09/01 - 1986/05/31
Concluded
|
Agrartechnik (Master)
Major in Agrartechnik
Universität Hohenheim Fakultät Agrarwissenschaften, Germany
"Entwicklung eines Rechnergesteuerten Mesßystem zur Bestimmung des Druckprofiles an Mähdrescherreinigungsanlage" (THESIS/DISSERTATION)
|
Sehr gut |
|
1977/03/01 - 1984/03/31
Concluded
|
Engenharia agronómica (Licence)
Major in Producion agrícola
Universidad de Buenos Aires Facultad de Agronomía, Argentina
"Entwicklung eines Rechnergesteuerten Messystem zur Bestimung des Druckprofiles an Maehdrescherreinigungsanlage" (Development
of a Measuring System to Determinate the Static Pressure Profile in the Cleaning System of Harvester Combines). Master Thesis.
Ins" (THESIS/DISSERTATION)
|
bom |
Affiliation
Science
| Category Host institution |
Employer | |
|---|---|---|
| 1989/11/01 - Current | Auxiliary Researcher (Research) | Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal |
Projects
Contract
| Designation | Funders | |
|---|---|---|
| 2021/10/01 - 2023/06/30 | BioPinus Biotransformação de resina proveniente de pinus para a produção de biofixadores à base de compostos biotivos e pigmentos
naturais com aplicação têxtil
Researcher
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
|
Fundação para a Ciência e a Tecnologia
Ongoing
|
| 2020/01/01 - 2022/12/31 | Identify Mechanisms of Microvascular ENDOTHELIAL Dysfunction to Predict and Prevent Cardiovascular Diseases (CVD)
UIDP/04462/2020
Researcher
iNOVA4Health, Portugal
|
Fundação para a Ciência e a Tecnologia
Ongoing
|
| 2020/01/01 - 2021/12/31 | Developing novel modulators of skin pigmentation
UIDP/04462/2020
Researcher
iNOVA4Health, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
| 2018 - 2020 | Mecanismos moleculares de internalização e processamento de melanina por queratinócitos
PTDC/BIA-CEL/29765/2017
Researcher
Universidade Nova de Lisboa, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
| 2016/06/01 - 2019/05/31 | Acoplamento de Fluídos Iónicos inspirados na Natureza e Sistemas Aquosos Bifásicos Microfluídicos para a Purificação de Anticorpos
Monoclonais
PTDC/QEQ-FTT/3289/2014
Researcher
Universidade Nova de Lisboa, Portugal
BioResources 4 Sustainability, Portugal |
Fundação para a Ciência e a Tecnologia
Concluded
|
| 2015/03/01 - 2017/12/31 | Development of a non-invasive method to measure blood glucose through the skin without need of calibration
UID/Multi /04462/2013
Researcher
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
|
iNOVA4Health
Concluded
|
| 2013/06 - 2015/05 | Development of microfluidic platform for single cell studies
PTDC/BBB-IMG/1225/2012
PTDC/BBB-IMG/1225/2012
Principal investigator
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
|
Ministério da Ciência Tecnologia e Ensino Superior |
| 2010/04/01 - 2014/09/30 | PIROVAC Improvement of current and development of new vaccines for theileriosis and babesios of small ruminants
Researcher
Forschungszentrum Borstel Leibniz-Zentrum für Medizin und Biowissenschaften, Germany
|
European Commission
Concluded
|
| 2013/06/03 - 2014/06/02 | InCell - Optical fiber tweezers for single cell manipulation and analysis
EXPL/BBB-IMG/0500/2012
Researcher
Instituto de Engenharia de Sistemas e Computadores Tecnologia e Ciência, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
| 2010/03 - 2013/08 | Hybrid electro-optical microfluidic device for single cell analysis
PTDC/SAU-BEB/102247/2008
Principal investigator
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
|
Ministério da Ciência Tecnologia e Ensino Superior
Concluded
|
| 2009/09 - 2012/03 | Development of ultra-sensitive detection methods and plant nano-vaccines for the fungi Fusarium spp. using nanotechnological
devices.
NANO/NTec-SQA/0131/2007
Principal investigator
Fundação para a Ciência e a Tecnologia, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
| 2005/07/01 - 2009/04/30 | Molecular characterization of Latin American and Mediterranean Babesia bovis and B. bigemina strains and its application for
the development of improved control strategies
Researcher
Universidad de Alcala de Henares, Spain
|
European Commission Sixth Framework Programme
Concluded
|
| 2005/07/01 - 2008/08/30 | INCOME
Researcher
Forschungszentrum Borstel Leibniz-Zentrum für Medizin und Biowissenschaften, Germany
|
European Commission Seventh Framework Programme for Research and Technological Development International Cooperation
Concluded
|
| 2006/01/01 - 2007/12/31 | Optical Fibre Sensors for Distributed Monitoring of Dissolved Oxygen and Temperature
Researcher
Instituto de Engenharia de Sistemas e Computadores, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
Outputs
Publications
| Book |
|
| Book chapter |
|
| Conference paper |
|
| Journal article |
|
Activities
Supervision
| Thesis Title Role |
Degree Subject (Type) Institution / Organization |
|
|---|---|---|
| 2021/01/01 - 2024/06/30 | Full humanized 3D melanoma skin model for physiological studies of tumor aggressiveness. This project aim is to produce an
innovative three-dimensional (3D) melanoma model with cells involved in tumor immune response to study the underlying mechanisms
affecting melanoma progression, invasion, and metastasis. The effect of current therapies, dabrafenib and pembrolizumab, also
will be addressed.
Supervisor
|
Biociências Moleculares (PhD)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
|
| 2020/04/01 - 2021/12/20 | 3D reconstruções human skin-on-a-chip modelo for anti-inflmatory drug evaluation. The aim of this master thesis will be th
edevelopment of a inflammation model in invitro developed human skin, as a tool for testing antinflammatory compounds.
Supervisor
|
Biologia Humana e Ambiente (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
|
| 2020/09/01 - 2021/09/30 | Aplicação tópica de bioflavonoides em epiderme humana reconstruída in vitro usando nanopartículas lipídicas. O trabalho de
mestardo esta focado na utilização de miniemulsões para a produção de NLCs (Nanostructured Lipid Carriers) para o estudo de
"drug delivery" em moelos de epiderme human reconstruída (RHE).
Co-supervisor
|
Biologia Humana e Ambiente (Master)
Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal
|
| 2016/03/01 - 2021/09/30 | Fully-humanized Skin-on-a-chip for medical applications. This project aims at developing an innovative microfluidic system
to grow and sustain a physiologically relevant human skin model and to access its potential applications.
Co-supervisor
|
Biociências Moleculares (PhD)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
|
| 2019/06/01 - 2021/06/30 | Desenvolvimento de um modelo 3D in vitro de melanoma cutâneo completamente humanizado com células mononucleadas de sangue
periférico (PBMCs).
Co-supervisor
|
Biociências Moleculares (Master)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
|
| 2019/09/01 - 2021/03/31 | Development of 3D skin model for studies of the autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS). THis work
aims teh development of an Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) model in a invitro skin model.
Co-supervisor
|
biologia molecular e genetica (Master)
Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal
|
| 2020/02/01 - 2021/02/24 | Development of an in vitro platform for a 3D microphysiological systems of human iPS-derived endothelial cells. This work
aims the development of a chip for co-culture of cells to build up a 3D microvascular network.
Co-supervisor
|
Engenharia de Materiais (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
|
| 2019/10/01 - 2021/02/24 | Development of substrates for reconstructed human dermis based on polyhydroxyalkanoates (PHAs) and FucoPol. This work demonstrated
the potential of naturally derived P(HBHVHHx)/FucoPol scaffolds for the reconstruction of human dermis.
Co-supervisor
|
Biotecnologia
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
|
| 2017/09/01 - 2019/10/18 | Study of the effects of the culture condition in the permeation of reconstructed human skin. This work provides a preliminary
insight into how these permeation parameters can be adjusted to produce an in vitro human epidermal equivalent that better
resembles the in vivo human epidermis. Although it is clear that further study is needed as permeability values are still
far from those observed in vivo.
Co-supervisor
|
Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal
|
| 2017/09/01 - 2019/02/28 | SuberSkin - plant defensive polymers in wound healing.
Co-supervisor
|
Bioquímica para a Saúde (Master)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
|
| 2016/04/01 - 2017/09/12 | Metabolomic analysis of the reconstructed epidermis cultivation protocol as a tool to improve the skin barrier properties.
In this work, a metabolomic analysis of the supernatant of the culture process (exometabolome) was performed by proton nuclear
magnetic resonance spectroscopy (1H-NMR) and high-performance liquid chromatography (HPLC). The uptake and secretion rates
for both the expansion of keratinocytes in monolayer culture and the reconstructed epidermis were determined for the several
metabolites observed by NMR, and for the amino acids.
Co-supervisor
|
Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal
|
| 2014/09/01 - 2016/04/28 | Development and Experimentation of New Tools for Bioassays with Red Blood Cells. The aim of this work was to develop new tools
for handling and studying of erythrocytes. In this context, biological nanoprobes were developed, combining Quantum Dots nanoparticles
with specific antibodies to detect proteins in erythrocytes. Also, a microfluidic platform was designed and constructed to
evaluate the cytotoxic effect in single-cell analysis of used QDs.
Supervisor
|
Biotecnologia (Master)
Universidade Nova de Lisboa, Portugal
|
| 2015/04/01 - 2015/12/09 | Microfluidics: A New Look At Cell Migration Analysis. Studying the effect of the surrounding environment of the embryonic
stem cells development is of highly relevance to understand its physiology. Different single-cell microchips were designed
and manufactured to study the migration of mouse embryonic fibroblasts (MEFs) cells coated and not coated with fibronectin
in response to an increase of serum concentration in the culture medium.
Supervisor
|
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
|
| 2011/09/01 - 2012/10/10 | Impedance spectroscopy applied to the characterization of parasitized cells in a microfluidics platform. This work is essentially
focused on the description of the implementation of the electronic component in a microfluidics device for molecular diagnostics
for the characterization of parasitized cells, as well as in the microfabrication of the devices themselves.
Co-supervisor
|
Ciências da Engenharia - Engenharia Biomédica e Biofísica (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
|
| 2007/03/01 - 2012/09/07 | Quantum Dots: Synthesis, Functionalization and Bioconjugation for Biological Applications. This work was based in teh development
of Quantum Dots (QDs) for biological applications and to study the impact of CdSe/ZnS core-shell QDs in cytoxity and genotoxicity
areas as well as their application in the electronic field will be also addressed in this doctoral work.Quantum dots, SILAR
method, biocompatible, bioconjugation, immunofluorescence assays, Babesia bovis, cytotoxicity, genotoxicity and MAPLE technique.
Co-supervisor
|
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
|
| 2006/04/01 - 2009/04/30 | Development of a new Babesia bovis diagnostic method and identification of new vaccine candidates
Supervisor
|
Bioquímica (PhD)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
|
| 2002/06/01 - 2006/02/15 | Identification and characterization of immunodominant proteins of Theileria uilenbergi to be used in the diagnosis of ovine
theileriosis in China
Supervisor
|
Bioquímica (PhD)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
|
| 1994/02/01 - 1998/09/20 | Desenvolvimento de um imunossensor para o diagnóstico da peste suina africana
Supervisor
|
Bioquímica (PhD)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
|
Jury of academic degree
| Topic Role |
Candidate name (Type of degree) Institution / Organization |
|
|---|---|---|
| 2022/02/08 | Cell-based Micro Device as a Tool for Predictive Intestinal Responses
(Thesis) Main arguer
|
Maria Inês Guedes (Master)
Universidade Nova de Lisboa Departamento de Física, Portugal
|
| 2020/09/15 | Biocatalysis in microfluidic systems: Biosensing and rapid-screening applications. The work discusses the development of an
enzymatic synthesis platform, a portable device for plant health assessment and platforms to contribute towards the development
of colon cancer treatments.
(Thesis) Main arguer
|
Eduardo João Silva Brás (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
|
| 2020/02/28 | Thin-Film Silicon Microelectromechanical Systems for Mass Sensing and Biosensing Applications. This work discuses the development
of cantilever for bioassays and MEMS including the construction by micro and nanomachining.
(Thesis) Main arguer
|
Rui Miguel Raposo Pinto (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
|
| 2019/12/03 | Optical Neurostimulation Spine Endoprosthesis. The research and experiments performed in this work hold a ”proof-of-concept”
utility and serve as starting point for further development of the technologies applied to stimulate neural systems.
(Thesis) Main arguer
|
Ricardo Morgado Marques (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
|
| 2019/12/03 | Low cost rapid prototyping of a microfluidic bioreactor for electrochemical sensing of 3D cancer cell cultures. This work
describes teh development of a microfluidic bioreactor to enable real time monitoring of cells in a 3D tissue engineered scaffold.
(Thesis) Main arguer
|
Pedro Miguel Quintas da Conceição (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
|
| 2018/12/12 | Microfluidic separation using aqueous two phase systems
(Thesis) Main arguer
|
Daniel Filipe Camarneiro Silva (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
|
| 2018/12/12 | Microfluidic separation using aqueous two phase systems. métodos de separação e purificação de biomoléculas já estabecidos
com o uso de ATPS num dispositivo microfluidico. O método escolhido para ser integrado no sistema foi a electroforese.
(Thesis) Arguer
|
Daniel Filipe Camarneiro Silva (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
|
| 2017/12/11 | Droplet Microfluidic Systems for Directed Evolution
(Thesis) Main arguer
|
Guilherme Araújo de Andrade (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
|
| 2017/11/13 | Magnetic components and microfluidics optimization on a Labon-a-Chip platform
(Thesis) Main arguer
|
João Ferreira Gil (Master)
Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal
|
Committee member
| Activity description Role |
Institution / Organization | |
|---|---|---|
| 2015/12/01 - Current | Coordinator of the ITQB-NOVA Postgraduate Programme on Research Practice and the Research Training Courses.
ITQB NOVA offers several research training options each corresponding to a number of credits (ECTS) to be awarded as University
Extension or Post-Graduation Courses. Selected students carry out their scientific training integrated in one of the research
laboratories at ITQB NOVA (or within the Oeiras Associated Laboratory).
Coordinator
|
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal |
| 2006/03/01 - Current | Member of the Sciecntific Council of the ITQB-UNL Antonio Xavier
Member
|
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal |
Course / Discipline taught
| Academic session | Degree Subject (Type) | Institution / Organization | |
|---|---|---|---|
| 2014/12/01 - Current | Post-Graduation program and University Extension Courses. ITQB NOVA offers several research training options each corresponding to a number of credits (ECTS) to be awarded as University Extension or Post-Graduation Courses. Summer students may apply to a short "Introduction to the Research Lab" course. | University Extension Courses & Postgraduate Programme on Research Practice (Pós-Graduação) | Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal |
| 2005/09/01 - 2020/03/31 | Biossensores. This course provides students with a generic view of the concepts underlying the design and production of biosensors (analytical sensors based on the combination of biological components and physicochemical transducers), as well as their technological variations, main applications and current and future challenges. The course's specific objectives are to introduce students to new sensory technologies in the field of biotechnology, namely with regard to its miniaturization. | Engenharia de Micro e Nanotecnologias (Mestrado) | Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal |
| 2019/11/18 - 2019/11/22 | Nano-processes for life sciences. Doctoral Course Module "MolBios". The general learning objective is to make the student aware of the importance of nanotechnologies in general and in particular their applications to the study and control of biomolecular processes in vitro, ex vivo and in vivo. | Biociências Moleculares (Doutoramento) | Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal |
Evaluation committee
| Activity description Role |
Institution / Organization | Funding entity | |
|---|---|---|---|
| 2008/03/20 - Current | Avaliador propostas de projetos de I&DT em Co-promoção no âmbito do QREN e Portugal 2020
Evaluator
|
Agência Nacional de Inovação SA, Portugal | Agência Nacional de Inovação SA |