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Sílvia Rebocho finished her PhD degree at FCT-UNL in 2015 on Sustainable Chemistry. During her PhD project, entitled ¿Biotransformation/separation routes to obtain pure enantiomers", she worked on the implementation of a new methodology for the separation of enantiomers of secondary alcohols, combining two sustainable technologies ¿ enzymes and supercritical technology using green/natural solvents. After that, she worked as a postdoctoral researcher in a project that involved the production of molecular imprinted polymers, using green technology to explore pharma and biomedical applications. During the last years, she also acquired experience in mentoring and training several students. She is the author and co-author of scientific papers involving enzymatic biocatalysis, supercritical fluid technology, vapor-liquid equilibrium, molecular imprinting techniques and extraction using natural deep eutectic systems. In the projects where she was involved, she always use alternative solvents and biocatalysis. Green Chemistry was always her focus of interest in research. Now, she is working with a new type of solvents, "deep eutectic systems (DES)" for the extraction of several bioactive compounds from plants. DES can be used in several areas such as biocatalysis, capture of carbon dioxide, electrochemistry or biomedical applications, among others. The use of these compounds is deeply involved in the development of pharmaceutical, cosmetic and food applications.
Identification

Personal identification

Full name
Sílvia Andreia da Silva Fernandes Rebocho
Gender
Female

Author identifiers

Ciência ID
471C-0F7D-9D00

Email addresses

  • s.rebocho@campus.fct.unl.pt (Professional)
Education
Degree Classification
2010/01/01 - 2015/12/01
Concluded
Sustainable Chemistry (Doutoramento)
Major in Doctoral Programme in Sustainable Chemistry
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
"Biotransformantion/separation routes to obatain pure enantiomers" (THESIS/DISSERTATION)
Unanimously approved
2007 - 2008/04/30
Concluded
Biotecnologia (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
"Síntese de acetato de decilo por catálise enzimática em meio supercrítico" (THESIS/DISSERTATION)
16
1999/10/01 - 2005
Concluded
Engenharia Biotecnológica (Licenciatura)
Universidade Lusófona de Humanidades e Tecnologias, Portugal
14
Affiliation

Others

Category
Host institution
Employer
2018/12/01 - Current Research Grant Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2016/04/01 - 2017/08/01 Post-doctoral grant Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2014/01/01 - 2014/09/30 Research grant Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2010/01/01 - 2013/12/31 PhD grant Fundação para a Ciência e a Tecnologia, Portugal
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2009/07/01 - 2009/12/31 Research grant Universidade de Lisboa Instituto Superior Técnico, Portugal
Universidade de Lisboa Instituto Superior Técnico, Portugal
2008/12/01 - 2009/04/30 Research grant Faculdade de Engenharia da Universidade do Porto, Portugal
Faculdade de Engenharia da Universidade do Porto, Portugal
2007/02/01 - 2007/11/30 Research grant Faculdade de Engenharia da Universidade do Porto, Portugal
Faculdade de Engenharia da Universidade do Porto, Portugal
Projects

Grant

Designation Funders
2018/12/01 - Current When solids become liquids: natural deep eutectic solvents for chemical process engineering
info:eu-repo/grantAgreement/EC/H2020/725034/EU
Research Fellow
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
European Commission
Ongoing
2016/04/01 - 2017/08/31 Mimicking nature Multi-functional affinity materials for targeted molecular recognition
IF/00915/2015/CP1224/CT0002
Post-doc Fellow
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
Concluded
2010/01/01 - 2014/09/30 BioMenthol: An Integrated Biotransformation/Separation Route to Obtain Pure Enantiomers
PhD Student Fellow
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
Concluded
2007/02/01 - 2008/11/30 Decyl acetate synthesis by enzyme catalysis in supercritical CO2
POCI/EQU/56732/2004
Research Fellow
Faculdade de Engenharia da Universidade do Porto, Portugal
Concluded
Outputs

Publications

Conference poster
  1. Rebocho, Sílvia. "Sustainable systems for the extraction and stabilization of bioactive compounds from aromatic plants". Paper presented in 1st International Greenering conference, 2021.
  2. Rebocho, Sílvia. "NADES as emerging sustainable systems for the extraction and stabilization of bioactive compounds from Rosemary". Paper presented in 1st International Greenering conference, 2021.
  3. Rebocho, Sílvia. "Natural Deep Eutectic Systems - versatile media for extraction and stabilization of antioxidants". Paper presented in 2 nd Food Chemistry Conference, 2019.
  4. Rebocho, Sílvia. "Extraction of Phenolics and Pigments from Yerba mate with Deep Eutectic Solvents". Paper presented in 1st International Meeting on Deep Eutectic Systems, 2019.
  5. Rebocho, Sílvia. "Development of a disposable molecularly imprinted electrochemical sensor". Paper presented in 16th European Meeting on Supercritical Fluids, 2017.
  6. Rebocho, Sílvia. "Enzymatic resolution/separation of sec-alcohols using green solvents". Paper presented in 14th European Meeting on Supercritical Fluids, 2014.
  7. Rebocho, Sílvia. "New approaches for the resolution of rac-menthol". Paper presented in 10th Conference on Supercritical Fluids and their Applications, 2013.
  8. Rebocho, Sílvia. "New strategy for the resolution/separation of sec-alcohols combining ionic acylating agents with supercritical CO2". Paper presented in Ionic Liquids: Faraday Discussion 154, 2011.
  9. Rebocho, Sílvia. "Enzymatic resolution-separation of sec-alcohols based on the use of ionic acylating agents in supercritical CO2". Paper presented in International School in Sustainable Chemistry 2010, 2010.
  10. Rebocho, Sílvia. "Solvent-free Enzymatic Synthesis of Decyl Acetate: The "Cherry on Top?"". Paper presented in VIII Iberoamerican Conference on Phase Equlibria and Fluid Properties for Process Design- EQUIFASE, 2009.
  11. Rebocho, Sílvia. "Decyl acetate synthesis by supercritical biocatalysis". Paper presented in II Encontro de Jovens Investigadores da Universidade do Porto, 2009.
  12. Rebocho, Sílvia. "Kinetic modelling of decyl acetate synthesis by enzymatic catalysis in supercritical CO2". Paper presented in II Encontro de Jovens Investigadores da Universidade do Porto, 2009.
  13. Rebocho, Sílvia. "Production of esters by biocatalysed transesterification in supercritical CO2 and hexane". Paper presented in International Conference on Renewable Resources & Biorefineries, 2007.
  14. Rebocho, Sílvia. "Rationalization of cutinase activity in sol-gel matrices". Paper presented in The role of Supercritical Fluid Technology in Pharmaceutical and Nutraceutical Food Processing, 2005.
  15. Rebocho, Sílvia. "Immobilization of cutinase in sol-gel". Paper presented in BIOTRANS 2005, 2005.
Journal article
  1. Vieira, Carolina; Rebocho, Sílvia; Craveiro, Rita; Paiva, Alexandre; Duarte, Ana Rita C.. "Selective extraction and stabilization of bioactive compounds from rosemary leaves using a biphasic NADES". Frontiers in Chemistry 10 (2022): http://dx.doi.org/10.3389/fchem.2022.954835.
    Accepted • 10.3389/fchem.2022.954835
  2. "Fractionated extraction of polyphenols from mate tea leaves using a combination of hydrophobic/ hydrophilic NADES". Current research in Food Science 5 (2022): 571-580. https://www.sciencedirect.com/science/article/pii/S2665927122000466?via%3Dihub.
    Open access • Published
  3. Rebocho, Sílvia; Cordas, Cristina M.; Viveiros, Raquel; Casimiro, Teresa. "Development of a ferrocenyl-based MIP in supercritical carbon dioxide: Towards an electrochemical sensor for bisphenol A". The Journal of Supercritical Fluids 135 (2018): 98-104. http://dx.doi.org/10.1016/j.supflu.2018.01.006.
    Published • 10.1016/j.supflu.2018.01.006
  4. Viveiros, Raquel; Rebocho, Sílvia; Casimiro, Teresa. "Green Strategies for Molecularly Imprinted Polymer Development". Polymers 10 3 (2018): 306. http://dx.doi.org/10.3390/polym10030306.
    Published • 10.3390/polym10030306
  5. Rebocho, Sílvia; Nunes, Ana V. M.; Najdanovic-Visak, Vesna; Barreiros, Susana; Paiva, Alexandre. "Experimental Determination and Modeling of the Phase Behavior of the CO2 + Propionic Anhydride Binary System at High Pressure". Journal of Chemical & Engineering Data 62 1 (2016): 210-213. http://dx.doi.org/10.1021/acs.jced.6b00595.
    Published • 10.1021/acs.jced.6b00595
  6. Rebocho, Sílvia; Nunes, Ana V.M.; Najdanovic-Visak, Vesna; Barreiros, Susana; Simões, Pedro; Paiva, Alexandre. "High pressure vapor–liquid equilibrium for the ternary system ethanol/(±)-menthol/carbon dioxide". The Journal of Supercritical Fluids 92 (2014): 282-287. http://dx.doi.org/10.1016/j.supflu.2014.06.006.
    Published • 10.1016/j.supflu.2014.06.006
  7. Paiva, Alexandre; Vidinha, Pedro; Angelova, Maria; Rebocho, Sílvia; Barreiros, Susana; Brunner, Gerd. "Biocatalytic separation of (R, S)-1-phenylethanol enantiomers and fractionation of reaction products with supercritical carbon dioxide". The Journal of Supercritical Fluids 55 3 (2011): 963-970. http://dx.doi.org/10.1016/j.supflu.2010.09.037.
    Published • 10.1016/j.supflu.2010.09.037
  8. Ribeiro, Adriano S.; Oliveira, Manuela V.; Rebocho, Si´lvia F.; Ferreira, Olga; Vidinha, Pedro; Barreiros, Susana; Macedo, Euge´nia A.; Loureiro, Jose´ M.. "Enzymatic Production of Decyl Acetate: Kinetic Study inn-Hexane and Comparison with Supercritical CO2". Industrial & Engineering Chemistry Research 49 16 (2010): 7168-7175. http://dx.doi.org/10.1021/ie902026d.
    Published • 10.1021/ie902026d
  9. Oliveira, Manuela V.; Rebocho, Sílvia F.; Ribeiro, Adriano S.; Macedo, Eugénia A.; Loureiro, José M.. "Kinetic modelling of decyl acetate synthesis by immobilized lipase-catalysed transesterification of vinyl acetate with decanol in supercritical carbon dioxide". The Journal of Supercritical Fluids 50 2 (2009): 138-145. http://dx.doi.org/10.1016/j.supflu.2009.05.003.
    10.1016/j.supflu.2009.05.003
Report
  1. Rebocho, Sílvia. 2005. Imobilização da Cutinase em sol-gel.
Thesis / Dissertation
  1. Rebocho, Sílvia. "Biotransformation/separation routes to obtain pure enantiomers". 2015. https://run.unl.pt/bitstream/10362/17097/1/Rebocho_2015.pdf.
  2. Rebocho, Sílvia. "SÍNTESE DE ACETATO DE DECILO POR CATÁLISE ENZIMÁTICA EM MEIO SUPERCRÍTICO". 2008. https://run.unl.pt/bitstream/10362/1392/1/Rebocho_2008.pdf.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2021/06/16 Extraction and Stabilization of Bioactive Compounds From Aromatic Plants Using Sustainable NADES 2nd International Meeting on Deep Eutectic Systems
Ana Rita Duarte (Lisbon, Portugal)
2019/07/31 Fractioned Extraction of Pigments and Polyphenols from Yerba mate using a Combination of Hydrophobic and Hydrophilic Deep Eutectic Solvents Natural Products in Drug Discovery and Human Health
Faculdade de Fármacia da Universidade de Lisboa (Lisbon, Portugal)
2009/08/23 Kinetic Modelling of Decyl Acetate Synthesis by Supercritical Biocatalysis WCCE8 - 8th World Congress of chemical Engineering
(Montreal, Canada)
2009/06/14 Decyl acetate synthesis by enzyme catalysis in sc-CO2 2nd Internacional Congress on Green Process Engineering,
(Venice, Italy)
2008/09/04 Decyl acetate synthesis by enzyme catalysis in scCO2 10.ª Conferência Internacional de Engenharia Química e Biológica – CHEMPOR 2008
(Braga, Portugal)

Supervision

Thesis Title
Role
Degree Subject (Type)
Institution / Organization
2020/07/01 - 2022/02/25 Sustainable systems for the extraction and stabilization of bioactive compounds from aromatic plants
Supervisor
Biotecnologia (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Jury of academic degree

Topic
Role
Candidate name (Type of degree)
Institution / Organization
2021/07/13 Deteção não-invasiva de biomarcadores de stress
(Thesis) Main arguer
Carla Cristina dos Reis Lopes (Other)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2020/07/07 Detecção de biomarcadores de stress físico e emocional através de técnicas não invasivas - Dopamina e Serotonina
(Thesis) Main arguer
Fátima Mendes Costa (Other)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Ad Hoc journal article review

Journal title (ISSN) Publisher
2022/03/09 - Current Food Analytical Methods Elsevier
2020/06/17 - Current Process Biochemistry (1359-5113) Elsevier

Committee member

Activity description
Role
Institution / Organization
2021/06/15 - 2021/06/17 Scientific conference "2nd International meeting on deep eutectic systems" I helped in tasks like program definition, sponsoring search, abstracts and registrations management, and other general management activities.
Member
Des. Solve FCT-UNL, Portugal
2019/06/24 - 2019/06/27 Scientific conference – "1st International meeting on deep eutectic systems" , I helped in tasks like program definition, sponsoring search, abstracts and registrations management, and other general management activities.
Member
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2011/06/22 - 2011/06/22 Hot and cold - Gas Chromatography for Molecular Discovery Chemistry Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2010/08/23 - 2010/08/27 Leuven Summer School on Ionic Liquids Ionic Liquids KU Katholieke Universiteit Leuven, Belgium
2009/06/25 - 2009/07/10 Life Long Learning Intensive Course - "SCF-GSCE Supercritical Fluids - Green Solvents in Chemical Engineering" Supercrical Fluids KOC University , Turkey

Mentoring / Tutoring

Topic Student name
2019/01/14 - 2019/06/28 Applied Chemist final project Aisa Baldé
2017/04/24 - 2017/05/29 Applied Chemistry Final Project Paula Marques
2017/01/23 - 2017/03/07 Chemical Engineering Final Project Adriana Pontes
2016/07/01 - 2016/10/30 Chemistry and Biochemical Engineering (MIEQB) final project Énio Correia
2016/04/15 - 2016/06/07 Applied Chemistry Final Project Daniela Velez
2016/04/15 - 2016/06/07 Applied Chemistry Final Project Fernando Nunes
2012/09 - 2013/09 MSc Biotechnology José Jorge Pinto