Identification
Personal identification
- Full name
- Daniel Freitas Chavarria
Citation names
- Chavarria, Daniel
Author identifiers
- Ciência ID
- 471E-8468-DEF7
- ORCID iD
- 0000-0002-7010-9808
- Scopus Author Id
- 57189521654
Email addresses
- danielfchavarria@gmail.com (Professional)
- daniel.chavarria@fc.up.pt (Professional)
Addresses
- Rua do Campo Alegre, s/n, 4169-007, Porto, Porto, Portugal (Professional)
Websites
- https://drugdiscoveryup.pt/ (Professional)
- https://www.researchgate.net/profile/Daniel-Chavarria-4 (Social media)
- https://www.scopus.com/authid/detail.uri?authorId=57189521654 (Professional)
Knowledge fields
- Exact Sciences - Chemical Sciences - Organic Chemistry
- Medical and Health Sciences - Basic Medicine - Medicinal Chemistry
- Medical and Health Sciences - Basic Medicine - Toxicology
- Natural sciences - Biological Sciences - Biochemistry
Languages
Language | Speaking | Reading | Writing | Listening | Peer-review |
---|---|---|---|---|---|
Portuguese (Mother tongue) | |||||
English | Upper intermediate (B2) | Upper intermediate (B2) | Upper intermediate (B2) | Upper intermediate (B2) |
Education
Degree | Classification | |
---|---|---|
2015/09 - 2020/01/17
Concluded
|
PhD in Pharmaceutical Sciences (Doutoramento)
Major in Toxicology
Universidade do Porto Faculdade de Farmácia, Portugal
"Development of new chemical entities based on natural scaffolds with therapeutic potential towards age-related disorders" (THESIS/DISSERTATION)
|
Approved |
2018/12/05 - 2018/12/07
Concluded
|
3rd MuTaLig Training School "CA15135 multi-targeting Biophysical Training School" (Outros)
Fraunhofer-Institut für Molekularbiologie und Angewandte Oekologie IME Bereich Translationale Medizin Aussenstelle ScreeningPort,
Germany
|
|
2017/05/02 - 2017/05/06
Concluded
|
37th Edition of the European School of Medicinal Chemistry (ESMEC) (Outros)
Università degli Studi di Urbino Carlo Bo Dipartimento di Scienze Biomolecolari, Italy
|
|
2012/09 - 2014/09
Concluded
|
Biochemistry (Mestrado)
Universidade do Porto Faculdade de Ciências, Portugal
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal "Desenvolvimento de Novos Antioxidantes Lipofílicos como Solução Terapêutica para Doenças Neurodegenerativas" (THESIS/DISSERTATION)
|
18 |
2009/09 - 2012/09
Concluded
|
Biochemistry (Licenciatura)
Universidade do Porto Faculdade de Ciências, Portugal
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal "Synthesis of chromone amides: a contribution for the development of monoamine oxidase B (MAO-B) inhibitors" (THESIS/DISSERTATION)
|
16 |
Affiliation
Science
Category Host institution |
Employer | |
---|---|---|
2020/03/16 - Current | Contracted Researcher (Research) | Universidade do Porto Faculdade de Ciências, Portugal |
Universidade do Porto Centro de Investigação em Química, Portugal | ||
2023/11/19 - 2023/12/03 | Visiting Researcher (Research) | Université de Montpellier, France |
2022/04/01 - 2022/04/30 | Visiting Researcher (Research) | Universidade do Porto Faculdade de Ciências, Portugal |
Mediagnost Gesellschaft für Forschung und Herstellung von Diagnostika GmbH, Germany | ||
2018/07/02 - 2019/06/04 | Visiting Researcher (Research) | Universidade de Santiago de Compostela, Spain |
2011/10 - 2012/06 | Research Trainee (Research) | Universidade do Porto Faculdade de Ciências, Portugal |
Universidade do Porto Centro de Investigação em Química, Portugal |
Others
Category Host institution |
Employer | |
---|---|---|
2015/09 - 2020/01/17 | PhD student, FCT Grant SFRH/BD/108119/2015 | Universidade do Porto Faculdade de Farmácia, Portugal |
2015/03/01 - 2015/06/30 | Research Grant, Project "Development of Functional Materials" | Universidade do Porto Centro de Investigação em Química, Portugal |
Projects
Contract
Designation | Funders | |
---|---|---|
2021/01/01 - Current | Plurianual Funding of the Associated Laboratory Institute of Molecular Sciences
LA/P/0056/2020
Researcher
Fundação para a Ciência e a Tecnologia, Portugal
|
Fundação para a Ciência e a Tecnologia
Ongoing
|
2025/01 - 2027/12 | TARGET-MJD: New molecules harnessing targeted protein degradation for the treatment of Machado-Joseph disease
HR24-00578
Researcher
Universidade do Porto Centro de Investigação em Química, Portugal
|
Fundación Bancaria Caixa d'Estalvis i Pensions de Barcelona 'la Caixa'
Ongoing
|
2024 - 2027 | IMPULSE: IMProving User experience, Long-term sustainability and Services of EU-OPENSCREEN
101132028
Researcher
|
European Commission |
2024/11 - 2026 | TaxReCode: Improving taxol response through the manipulation of the cancer tubulin
CI24-10034
Researcher
Universidade do Porto Faculdade de Ciências, Portugal
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal |
Fundación Bancaria Caixa d'Estalvis i Pensions de Barcelona 'la Caixa'
Ongoing
|
2024/10/07 - 2025/07/31 | DMD4PD-Development of a disease-modifying drug for Parkinson’s Disease
0002D1C4C5
Researcher
Universidade do Porto Faculdade de Ciências, Portugal
|
Universidade do Porto |
2023/03/01 - 2025/02/28 | MitoTARGET4AD: Improving Nature for a Novel Disruptive Treatment for Alzheimer's Disease
2022.15117.CBM
Researcher
Universidade do Porto Faculdade de Ciências, Portugal
Université de Montpellier, France |
Fundação para a Ciência e a Tecnologia |
2020/01/01 - 2024/12/31 | CIQUP - Financiamento Plurianual da Unidade de I&D CIQUP - Centro de Investigação em Química da Universidade do Porto - Financiamento
Base
UIDB/00081/2020
Researcher
Universidade do Porto Centro de Investigação em Química, Portugal
|
Fundação para a Ciência e a Tecnologia |
2020/01/01 - 2024/12/31 | “CIQUP: Financiamento Plurianual da Unidade de I&D CIQUP – Centro de Investigação em Química da Universidade do Porto – Financiamento
programático” (UIDP/00081/2020)
UIDP/00081/2020
Researcher
Universidade do Porto Centro de Investigação em Química, Portugal
|
Fundação para a Ciência e a Tecnologia |
2023/01 - 2024/06 | DeFend: De-ironing Friedreich's Ataxia with innovative mitochondria-targeted chelators
2022.04633.PTDC
2022.04633.PTDC
Co-Principal Investigator (Co-PI)
Universidade do Porto Faculdade de Ciências, Portugal
|
Fundação para a Ciência e a Tecnologia
Ongoing
|
2022/02/01 - 2023/07/31 | NOXIous - Development of bona fide targeted covalent inhibitors to unravel NOX2 crystal structure
Principal investigator
Universidade do Porto Centro de Investigação em Química, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
2022/07/01 - 2023/06/30 | MitoBOOST v2.0 - A Proof of Concept for the Use of Mitochondria-Targeted Polyphenols to Treat Non-Alcoholic Fatty Liver Disease
CENTRO-01-0145-FEDER-181226
Researcher
Universidade de Coimbra, Portugal
Universidade do Porto Faculdade de Ciências, Portugal |
Agência para a Competitividade e Inovação IP
Concluded
|
2021/06/01 - 2023/05/31 | PT-OPENSCREEN - NORTE-01-0145-FEDER-085468: Infraestrutura Nacional para a Química Biológica e Genética
NORTE-01-0145-FEDER-085468
Researcher
Universidade do Porto Centro de Investigação em Química, Portugal
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal Universidade do Minho, Portugal Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal Instituto Nacional de Engenharia Biomédica, Portugal |
Comissao de Coordenacao e Desenvolvimento Regional do Norte
Ongoing
|
2018/07/26 - 2022/07/25 | ABFISH: Development of new antibiotics for aquaculture
POCI-01-0145-FEDER-028397
Researcher
Universidade do Porto Centro de Investigação em Química, Portugal
Universidade do Porto Faculdade de Engenharia, Portugal |
Fundação para a Ciência e a Tecnologia
Concluded
|
2017 - 2021 | mtFOIE GRAS: Non-invasive Profiling of Mitochondrial Function in Non Alcoholic Fatty Liver Disease-MSCA-RISE-2016
734719
Researcher
Universidade do Porto Centro de Investigação em Química, Portugal
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal |
European Commission |
2017 - 2021 | Foie Gras-Bioenergetic Remodeling in the Pathophysiology and Treatment of Non-Alcoholic Fatty Liver Disease -MSCA-ITN-2016
- Innovative Training Networks
722619
Researcher
Universidade do Porto Centro de Investigação em Química, Portugal
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal |
European Commission |
2018/07/26 - 2020/01/17 | COMT4brain: Development of centrally-active and safe catechol O-methyltransferase inhibitors
POCI-01-0145-FEDER-029164
PhD Student Fellow
Universidade do Porto Centro de Investigação em Química, Portugal
Universidade do Porto Faculdade de Medicina, Portugal |
Fundação para a Ciência e a Tecnologia
Concluded
|
2018/07/26 - 2020/01/17 | SkinShield - Redox-active phytochemicals triggering mitochondrial hormesis: developing a new generation of cosmetic active
ingredients
PTDC/BIA-MOL/28607/2017
POCI-01-0145-FEDER-02860
PhD Student Fellow
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Universidade do Porto Centro de Investigação em Química, Portugal |
Fundação para a Ciência e a Tecnologia
Concluded
|
2016/04/01 - 2019/09/30 | MitoBOOST: A Next-Generation Therapeutics for Non-Alcoholic Fatty Liver Disease Based on Smart Antioxidant Delivery to Mitochondria
PTDC/DTP-FTO/2433/2014
PhD Student Fellow
Universidade do Porto Faculdade de Ciências, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
2016/06/01 - 2019/05/31 | SAM: Sustainable Advanced Materials (SAM)
Norte-01-0145-FEDER-000028
PhD Student Fellow
|
Fundação para a Ciência e a Tecnologia
Concluded
|
2015/09/01 - 2018/02/28 | TOX-OER - Learning Toxicology through Open Educational Resources
2015-1-ES01-KA203-015957
Colaboration
Universidade do Porto Faculdade de Farmácia, Portugal
|
Erasmus Plus
Concluded
|
2015/03/01 - 2015/06/30 | Development of Functional Materials
NORTE-07-0124-FEDER-000065
Master Student Fellow
Universidade do Porto Faculdade de Ciências, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
Outputs
Publications
Book chapter |
|
Conference abstract |
|
Conference poster |
|
Journal article |
|
Thesis / Dissertation |
|
Intellectual property
Provisional application for patent |
|
Activities
Oral presentation
Presentation title | Event name Host (Event location) |
|
---|---|---|
2024/06/17 | Design, Synthesis and human monoamine oxidase inhibitory activity of 2-aroylbenzofuran derivatives: a new route towards hMAOs inhibition | XIII Meeting Paul Ehrlich Euro-PhD Network & COST ACTION
Sapienza university of Rome (Rome, Italy)
|
2024/04/24 | Propargylamine-containing compounds for neurodegenerative diseases: biological activity, physicochemical properties and docking studies | 4th MMCS: Harnessing the Power of New Drug Modalities
(Barcelona, Spain)
|
2024/02/07 | Pharmacodynamic evaluation of novel Catechol-O-methyltransferase inhibitors | 54th Meeting of the Portuguese Society of Pharmacology
NOVA Medical School (Lisbon, Portugal)
|
2022/07/04 | Brick by brick: pharmacophore mapping of chromone-based MAO-B inhibitors | 29th Young Research Fellows Meeting, Nantes, France.
Nantes Université (Nantes, France)
|
2021/12/09 | New Potential MAO-B/p38 MAPK Dual Inhibitors Targeting Neuroinflammation in Alzheimer's Disease. (Virtual event) | 2nd International Conference on Neuroprotection by Drugs, Nutraceuticals, and Physical Activity
Università di Bologna (Italy)
|
2021/10/07 | Tackling antimicrobial resistance with novel phytochemical-based conjugates: a structure-activity-toxicity study. | E-Conference on Innovation in Microbial Control
(Porto, Portugal)
|
2021/07/26 | Development of new chemical entities based on natural scaffolds with therapeutic potential towards age-related disorders | Paul Ehrlich Virtual Meeting
Università degli Studi "Magna Graecia" di Catanzaro (Catanzaro, Italy)
|
2021/07/26 | Mapping chromone-3-phenylcarboxamide pharmacophore: quid est veritas? | Paul Ehrlich Virtual Meeting 2021
Università degli Studi "Magna Graecia" di Catanzaro (Catanzaro, Italy)
|
2020/03/05 | Mapping the benzopyran chromone-3-carboxamide pharmacophore: structure-activity-toxicity and efflux transport studies | 4th WG meeting - Final status of WG activities within the MuTaLig COST Action
Faculty of Pharmacy, Ege University (Izmir, Turkey)
|
2020/02/22 | Synthesis and structure-activity relationship study of piperine derivatives with MAO-B and P-gp inhibitory activities | II Workshop meeting CIQUP
Faculty of Sciences, University of Porto (Porto, Portugal)
|
2019/06/13 | Lessons from black pepper: moving from one to multitarget-directed ligands by diversity-oriented synthesis | IX Meeting of the Paul Ehrlich Euro-PhD Network & 4th Annual meeting – MuTaLig COST Action meeting
University "Magna Græcia" of Catanzaro (Catanzaro, Italy)
|
2019/06/13 | Looking for the Pharmacophore of Benzopyran MAO-B Inhibitors | IX Meeting of the Paul Ehrlich Euro-PhD Network & 4th Annual meeting – MuTaLig COST Action meeting
Università degli Studi "Magna Graecia" di Catanzaro (Catanzaro, Italy)
|
2019/02/23 | Development of Dual-Target Agents Based on Piperine Scaffold | 3rd WG meeting – Activities of young investigators within the WG MuTaLig COST Action (CA15135)
University of Paris Descartes (Paris, France)
|
2019/02/23 | Design and development of new chemical entities for the treatment of Parkinson disease | 3rd WG meeting – Activities of young investigators within the WG MuTaLig COST Action (CA15135)
Faculté de Pharmacie de Paris, Université Paris DESCARTES (Paris, France)
|
2015/07/02 | Antioxidants: from Nature to drug prototypes. | International Workshop on "Biochemistry, Physiology and Pharmacology of Oxidative Stress
Sapienza University of Rome (Roma, Italy)
|
2015/05/13 | Exploring Cinnamic Acid Scaffold: Development of Promising Neuroprotective Lipophilic Antioxidants | VIII Encontro de Jovens Investigadores da UP (IJUP)
Universidade do Porto (Porto, Portugal)
|
2015/03/27 | Finding a therapeutic solution for neurodegenerative diseases: design and synthesis of novel neuroprotective agents | III ENEQUI – “Ilumina o teu conhecimento!
Sociedade Portuguesa de Química (Aveiro, Portugal)
|
2014/06/04 | Biology-oriented development of lipophilic antioxidants with neuroprotective activity | 8th International Conference on Polyphenols Applications – ISANH Polyphenols 2014
International Society of Antioxidants in Nutrition and Health (ISANH) (Lisboa, Portugal)
|
Supervision
Thesis Title Role |
Degree Subject (Type) Institution / Organization |
|
---|---|---|
2023/04/03 - Current | De-ironing Friedreich's Ataxia with innovative mitochondria-targeted chelators
Co-supervisor
|
Química (PhD)
Universidade do Porto Faculdade de Ciências, Portugal
|
2022/10/01 - Current | Bona fide NOX2 inhibitors: a new therapeutic solution for neurodegenerative diseases?
Supervisor
|
Química (PhD)
Universidade do Porto Faculdade de Ciências, Portugal
|
2023/09 - 2024/11/19 | Desenvolvimento de novos quelantes de ferro direcionados à mitocôndria com potencial aplicação da Ataxia de Friedreich
Co-supervisor
|
Bioquímica (Master)
Universidade do Porto Faculdade de Ciências, Portugal
|
2024/02/19 - 2024/07/27 | Desenvolvimento de inibidores da NOX2 para regulação da neuroinflamação crónica em doenças neurodegenerativas
Supervisor
|
Bioquímica (Other)
Universidade do Porto Faculdade de Ciências, Portugal
|
2023/09 - 2024/07 | Synthesis and evaluation of novel Spindle Assembly Checkpoint inhibitors
Supervisor
|
Bioquímica (Master)
Universidade do Porto Faculdade de Ciências, Portugal
|
2023/02/17 - 2023/07/04 | Desenvolvimento de novos inibidores da NOX2 baseados na estrutura do VAS2870
Supervisor
|
Química (Degree)
Universidade do Porto Faculdade de Ciências, Portugal
|
2022/10 - 2023/02 | NOX2 como alvo terapêutico para desenvolvimento de novos fármacos para as doenças neurodegenerativas
Supervisor
|
Bioquímica
Universidade de Trás-os-Montes e Alto Douro, Portugal
|
2021/02/15 - 2021/07/31 | Development of selective NOX2 inhibitors
Supervisor
|
Química (Degree)
Universidade do Porto Faculdade de Ciências, Portugal
|
2020/02 - 2020/07 | Evaluation of drug-like properties of innovative multitarget-directed ligands for treatment of Parkinson's disease
Co-supervisor
|
Bioengenharia (Master)
Universidade do Porto Faculdade de Engenharia, Portugal
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal |
2016/04 - 2016/07 | Desenvolvimento de novos antioxidantes tendo como base modelos naturais
Co-supervisor
|
Química (Degree)
Universidade do Porto Faculdade de Ciências, Portugal
|
Event organisation
Event name Type of event (Role) |
Institution / Organization | |
---|---|---|
2023/06/26 - 2023/07/12 | Co-organizer/Trainer of the international course "Drug Discovery 2030: A Roadmap for a New Decade". This course aimed to improve,
via virtual classes and a week of intensive training, the participants skills in Medicinal Chemistry and Chemistry Biology.
This course was funded with support from the European Commission and implemented within the framework of Blended Intensive
Programmes (BIPs), a new format of Erasmus+ mobility. https://drugdiscovery2030.pt/ (2023/06/26 - 2023/07/12)
Other (Co-organisor)
|
Universidade do Porto Faculdade de Ciências, Portugal |
2021/05/07 - 2021/05/21 | Co-organizer of the "First Webinar on Medicinal Chemistry". Three-day webinar (May 7th, 14th and 21st) organized within the
framework of the Medicinal Chemistry curricular unit and opened to the scientific community. The webinar was aimed to bring
together renowned researchers from academy and industry that exchanged and shared their experiences on aspects of Drug Discovery
and Development. (2021/05/07 - 2021/05/21)
Workshop (Co-organisor)
|
Universidade do Porto Faculdade de Ciências, Portugal |
2018/06/12 - 2018/06/14 | Member of the Local Organizing Committee during the "8th meeting of Paul Ehrlich MedChem EuroPhD Network" (2018/06/12 - 2018/06/14)
Congress (Member of the Organising Committee)
|
Universidade do Porto Faculdade de Ciências, Portugal |
2017/09/22 - 2017/09/24 | Member of the Local Organizing Committee during the "EpiChemBio and MuTaLig COST actions joint meeting" (2017/09/22 - 2017/09/24)
Congress (Member of the Organising Committee)
|
Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal |
2016/06/29 - 2016/07/01 | Member of the Local Organizing Committee during the "10th World Congress on Polyphenols Applications" (2016/06/29 - 2016/07/01)
Congress (Member of the Organising Committee)
|
Instituto Politécnico do Porto Instituto Superior de Engenharia do Porto, Portugal |
Event participation
Activity description Type of event |
Event name Institution / Organization |
|
---|---|---|
2024/05/08 - 2024/05/10 | IJUP - Investigação Jovem da Universidade do Porto (17ª edição)
Conference
|
IJUP - Investigação Jovem da Universidade do Porto (17ª edição)
Universidade do Porto, Portugal
|
2022/11/16 - 2022/11/18 | XXVI Encontro Galego-Portugués de Química
Conference
|
Universidade de Santiago de Compostela Facultade de Química, Spain
|
2022/10/17 - 2022/10/17 | How to protect a research result via patent and how to accommodate this protection in the proposal budget for funding
Workshop
|
UPTEC Associação de Transferência de Tecnologia da Asprela, Portugal
|
2022/06/14 - 2022/06/16 | X Meeting of the Paul Ehrlich Euro-PhD Network
Conference
|
Universitat Ramon Llull IQS, Spain
|
2021/10/07 - 2021/10/08 | E-Conference on Innovation in Microbial Control
Conference
|
Universidade do Porto Faculdade de Engenharia, Portugal
Universidade do Porto Faculdade de Ciências, Portugal |
2021/07/26 - 2021/07/28 | Paul Ehrlich Virtual Meeting 2021
Conference
|
Università degli Studi Magna Graecia di Catanzaro, Italy
|
2020/12/01 - 2020/12/01 | Webinar "Back to basics: Fundamental concepts of HPLC and UHPLC" (1 h).
Organisation's name: VWR (part of Avantor).
Other
|
|
2020/07/16 - 2020/07/16 | Webinar "Improving cell-based assays and their future in drug discovery" (1h). Organisation's name: ICBAS/FFUP library, University
of Porto, Portugal
Other
|
|
2020/03/05 - 2020/03/06 | 4th WG meeting - Final status of WG activities within the MuTaLig COST Action (CA15135)
Conference
|
Ege Üniversitesi Eczacilik Fakültesi, Turkey
|
2020/02/22 - 2020/02/22 | II workshop meeting CIQUP
Conference
|
Universidade do Porto Faculdade de Ciências, Portugal
|
2019/06/13 - 2019/06/15 | IX Meeting of the Paul Ehrlich Euro-PhD Network & 4th Annual meeting – MuTaLig COST Action meeting
Conference
|
Università degli Studi Magna Graecia di Catanzaro, Italy
|
2019/02/23 - 2019/02/24 | 3rd WG meeting - Activities of young investigators within the WG MuTaLig COST Action (CA15135)
Conference
|
Université de Paris UFR de Pharmacie, France
|
2019/02/20 - 2019/02/22 | 26th Young Research Fellows Meeting (YRFM)
Conference
|
Université de Paris UFR de Pharmacie, France
|
2018/10/18 - 2018/10/19 | 3rd Annual meeting - MuTaLig COST ACTION (CA15135)
Conference
|
University of Malta, Malta
|
2018/07/12 - 2018/07/14 | 8th meeting of Paul Ehrlich MedChem EuroPhD Network
Conference
|
Universidade do Porto Faculdade de Ciências, Portugal
|
2018/03/15 - 2018/03/16 | 2nd WG meeting - Status of WG activities of the MuTaLig COST Action (CA15135)
Conference
|
Universidad de La Laguna, Spain
|
2018/02/16 - 2018/02/20 | "Project TOX-OER (Learning Toxicology through Open Educational Resources)". This project was funded with support from the
European Commission and implemented in the framework of Erasmus+ programme under the Action KA2 -Cooperation for Innovation
and the Exchange of Good Practices Strategic Partnerships for Higher Education-. Main activity: Preparation of contents in
Portuguese for the "Module 7.1.: Patents and Patent Application" (http://moodle.toxoer.com/)
Other
|
Project TOX-OER (Learning Toxicology through Open Educational Resources)
Universidade do Porto Faculdade de Farmácia, Portugal
|
2017/11/27 - 2017/11/27 | Participation in seminar (4 h). Dissemination of the Toxicology course MOOC (Massive Open Online Course). This initiative
was promoted within the scope of the project Erasmus+ TOX-OER - Learning Toxicology through Open Educational Resources.
Seminar
|
Dissemination of the Toxicology course MOOC (Massive Open Online Course)
Universidade do Porto Faculdade de Farmácia, Portugal
|
2017/09/22 - 2017/09/24 | EpiChemBio (CM1406) and MuTaLig COST (CA15135) actions joint meeting
Conference
|
Universidade do Porto Faculdade de Ciências, Portugal
|
2017/08/25 - 2017/08/27 | 7th meeting of Paul Ehrlich MedChem EuroPhD Network
Conference
|
Technischen Universität Wien, Austria
|
2016/11/18 - 2016/11/20 | 6th Meeting of the Paul Ehrlich MedChem Euro-PhD Network and Mutalig COST Action, 1st WG meeting/ Poly-pharmacology expanding
Paul Ehrlich’s magic bullet concept
Conference
|
Semmelweis Egyetem, Hungary
|
2016/05/18 - 2016/05/18 | Participation in training initiative (4 h).
Other
|
Introdução à escrita de um artigo científico: artigo original e artigo de revisão
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Universidade do Porto Faculdade de Farmácia, Portugal |
2016/04/27 - 2016/04/27 | Participation in training initiative (4 h).
Other
|
Introdução ao EndNote X7: da criação de uma biblioteca à escrita de um documento
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Universidade do Porto Faculdade de Farmácia, Portugal |
2016/03/16 - 2016/03/16 | Participation in training initiative (4 h).
Other
|
Web of Science e Scopus: pesquisa em bases de dados de citações
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Universidade do Porto Faculdade de Farmácia, Portugal |
2015/07/03 - 2015/07/05 | V Meeting of the Paul Ehrlich MedChem Euro-PhD Network
Conference
|
Uniwersytet Jagiellonski w Krakowie, Poland
|
2015/05/13 - 2015/05/15 | VIII Encontro de Jovens Investigadores da UP (IJUP)
Conference
|
Universidade do Porto, Portugal
|
2014/05/30 - 2014/05/30 | Participation in workshop (1 day)
Workshop
|
3rd workshop on Medicinal Chemistry - Drug Design and Development: Understanding the R&D Process
Universidade do Porto Faculdade de Ciências, Portugal
|
2013/10 - 2014/01 | Participation in english course (30 h)
Other
|
English course, Level B2.1 (Vantage)
Universidade do Porto Faculdade de Ciências, Portugal
|
2013/03/22 - 2013/03/24 | Participation in meeting (3 days)
Meeting
|
VI ENEBIOQ - Encontro Nacional de Estudantes de Bioquímica
Universidade de Aveiro, Portugal
|
2012/02/17 - 2012/02/19 | V Encontro de Jovens Investigadores da UP (IJUP)
Conference
|
Universidade do Porto, Portugal
|
2011/09/08 - 2011/09/09 | Participation in workshop (2 days)
Workshop
|
New-indigo workshop - Antitumour and antiparasitic drugs
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
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Jury of academic degree
Topic Role |
Candidate name (Type of degree) Institution / Organization |
|
---|---|---|
2024/09/09 | Development of predicted N(2)-alkylated oxotriazioindole ((R)-OTI) aldose reductase inhibitors for improved OTI drug like
bioavailability
(Thesis) Main arguer
|
Bruno Rangel da Silva Mansano (Other)
Universidade do Porto Faculdade de Ciências, Portugal
|
2024/07/27 | Bona fide NOX2 inhibition: a promising strategy for the development of new neuroprotective agents
Supervisor
|
Bárbara Jayet Ribeiro (Other)
Universidade do Porto Faculdade de Ciências, Portugal
|
2023/07/27 | Desenvolvimento de novos inibidores da NOX2 baseados na estrutura do VAS2870
Supervisor
|
Vera Lúcia Pinheiro Amaral (Other)
Universidade do Porto Faculdade de Ciências, Portugal
|
2023/07/21 | Desenvolvimento de novas estratégias para o tratamento da resistência a antibióticos
(Thesis) Main arguer
|
Joana Parreira Quadros Ferreira (Other)
Universidade do Porto Faculdade de Ciências, Portugal
|
2023/02/17 | NOX2 como alvo terapêutico para desenvolvimento de novos fármacos para as doenças neurodegenerativas
Supervisor
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Andreia Ferreira (Other)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
|
2021/11/15 | In vitro effects of mitochondria-targeted antioxidants in ovarian and endometrial cancer
(Thesis) Main arguer
|
Mariana Antunes Castelôa (Master)
Universidade do Porto Faculdade de Ciências, Portugal
|
2021/07/13 | Development of selective NOX2 inhibitors
Supervisor
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Inês Filipa Cabral Real Libânio (Other)
Universidade do Porto Faculdade de Ciências, Portugal
|
2020/07/22 | Design and development of cationic nanoparticles for the delivery of a catechol O-methyltransferase inhibitor to the brain
(Thesis) Main arguer
|
Rúben Faria Correia (Other)
Universidade do Porto Faculdade de Ciências, Portugal
|
Conference scientific committee
Conference name | Conference host | |
---|---|---|
2024/05/08 - 2024/05/10 | IJUP2024 - Investigação Jovem na Universidade do Porto (Representative for Chemistry) | University of Porto |
Course / Discipline taught
Academic session | Degree Subject (Type) | Institution / Organization | |
---|---|---|---|
2022/09 - Current | Thesis (Q702) | Química (Doutoramento) | Universidade do Porto Faculdade de Ciências, Portugal |
2020/02 - Current | Invited professor of Medicinal Chemistry | Biochemistry (Mestrado) | Universidade do Porto Faculdade de Ciências, Portugal |
2023/09 - 2024/09 | Dissertation (BQ5001) | Bioquímica (Mestrado integrado) | Universidade do Porto Faculdade de Ciências, Portugal |
2024/02/17 - 2024/07/27 | Project/internship (BIOQ3003) | Bioquímica | Universidade do Porto Faculdade de Ciências, Portugal |
2023/02 - 2023/07 | Project/Internship (Q208) | Química (Licenciatura) | Universidade do Porto Faculdade de Ciências, Portugal |
2021/02 - 2021/07 | Project/Internship (Q208) | Química (Licenciatura) | Universidade do Porto Faculdade de Ciências, Portugal |
Interview (newspaper / magazine)
Activity description | Newspaper / Forum | |
---|---|---|
2024/10/30 | FCUP in a project to improve breast cancer treatment with Taxol | Notícias U.Porto and FCUP |
2024/10/17 | Three projects from FCUP highlighted on BIP PROOF 2024/25 | Notícias U.Porto and FCUP |
2023/04/04 | Portuguese researchers develop antioxidant to fight neurodegenerative diseases | SIC Notícias |
2023/04/04 | FCUP develops antioxidant with potential to fight neurodegenerative diseases | Jornal de Notícias |
2023/04/04 | Newly developed antioxidant with potential to fight neurodegenerative diseases | Diário de Notícias |
2023/04/04 | Portuguese researchers develop antioxidant with potential to fight neurodegenerative diseases | CNN Portugal |
2023/04/04 | How Lego Chemistry can help to fight neurodegenerative diseases | Notícias U.Porto and FCUP |
Journal scientific committee
Journal title (ISSN) | Publisher | |
---|---|---|
2022/09/15 - 2023/05/31 | Molecules, "Advances in Drug Discovery Research in Europe"; https://www.mdpi.com/journal/molecules/special_issues/2PSM2TE9VP | MDPI AG |
2020/07/07 - 2021/01/31 | Molecules, "Recent Advances in CNS Drug Discovery"; https://www.mdpi.com/journal/molecules/special_issues/CNS_Drug | MDPI AG |
Mentoring / Tutoring
Topic | Student name | |
---|---|---|
2024/03 - Current | De-ironing Friedreich’s Ataxia with innovative mitochondria-targeted chelators. MSc Fellowship. Project DEFEND:De-ironing Friedreich’s Ataxia with innovative mitochondria-targeted chelators” (2022.04633.PTDC). Role: Co-supervisor | Catarina Alves |
2024/09/01 - 2025/02/28 | Use of scaffold-hopping to obtain new heterocyclic chalcone mimetics to develop compounds with anti-prion activity. International Mobility. Role: Supervisor. | Lucas Caruso (PhD in Chemistry, Federal Rural University of Rio de Janeiro, Brazil) |
2024/02 - 2024/07 | Desenvolvimento de novas moléculas para o tratamento de doenças associadas o stress oxidativo | Teresa Baptista Rocha |
2023/04/12 - 2023/12/21 | In vitro evaluation of bioactivity (antioxidant, enzyme inhibition) of plant extracts. Role: mentor | Jessica Ceramella (Post doc researcher, University of Calabria, Italy) |
2023/03/01 - 2023/06/02 | Enzymatic assays for the evaluation of the activity of acetylcholinesterase and monoamine oxidase B inhibitors. International mobility of PhD student. Role: Supervisor | Michele Collucia (PhD in Pharmaceutical Sciences, University of Rome, Italy) |
2022/10/15 - 2023/05/14 | Design and synthesis of new chemical entities based on VAS2870. BSc fellowship. Project NOXIous - Development of bona fide targeted covalent inhibitors to unravel NOX2 crystal structure (EXPL/BIA-BQM/0492/2021) (7 months). Role: supervisor | Carla Patrícia Costa Lima |
2022/10/06 - 2023/02/02 | Insights into the discovery of new neuroprotective agents. International mobility of MSc under the ERASMUS+ programme. Role: Mentor | Sara Bertolami (MSc in Pharmaceutical Chemistry and Technology, University of Pisa, Italy) |
2022/05/01 - 2022/09/30 | Tailoring VAS27870 scaffold to develop new covalent NOX2 inhibitors. MSc fellowship (5 months). Project NOXIous - Development of bona fide targeted covalent inhibitors to unravel NOX2 crystal structure (EXPL/BIA-BQM/0492/2021). Role: Supervisor | Mariana Antunes Castelôa |
2020/02/20 - 2020/04/20 | Synthesis and biological evaluation of urolithin derivatives for neurodegenerative diseases. International mobility of MSc under the ERASMUS+ programme. Role: Mentor | Giulia Fusi (MSc in Pharmaceutical Chemistry and Technology, University of Pisa, Italy) |
Other jury / evaluation
Activity description | Institution / Organization | |
---|---|---|
2024/08/08 - Current | Member of the selection committee for the attribution of one research grant (Master’s degree) under the project UIDB/00081/2020-RG1. Role: 2nd alternate member. | Universidade do Porto Faculdade de Ciências, Portugal |
2024/04/01 - Current | Member of the selection committee for the attribution of one research grant (Master’s degree) under the project UIDB/00081/2020-RG1. Role: 1st effective member. | Universidade do Porto Faculdade de Ciências, Portugal |
2024/03/13 - Current | Member of the selection committee for the attribution of one research grant (Master’s degree) under the project DeFend: De-ironing Friedreich’s Ataxia with innovative mitochondria-targeted chelators” (2022.04633.PTDC). Role: 2nd effective member. | Universidade do Porto Faculdade de Ciências, Portugal |
2022/08/28 - Current | Member of the selection committee for the attribution of one research grant (Bachelor’s degree) under the project “NOXIOUS – Development of bona fide targeted covalent inhibitors to unravel NOX2 crystal structure” (EXPL/BIA-BQM/0492/2021). Role: President. | Universidade do Porto Faculdade de Ciências, Portugal |
2022/03/24 - Current | Member of the selection committee for the attribution of one Master research grant (Master’s degree) under the project “NOXIOUS – Development of bona fide targeted covalent inhibitors to unravel NOX2 crystal structure” (EXPL/BIA-BQM/0492/2021). Role: President. | Universidade do Porto Faculdade de Ciências, Portugal |
Distinctions
Award
2024 | Best article Prize (Modulating Cytotoxicity with Lego-like Chemistry: Upgrading Mitochondriotropic Antioxidants with Prototypical
Cationic Carrier) in IACOBUS-Papers cross-border scientific collaboration between the northern reg
Xunta de Galicia, Spain
|
2022 | Award for best poster presentation (X Meeting of the Paul Ehrlich Euro-PhD Network, 2022, July 14-16th, Barcelona, Spain)
Universitat Ramon Llull IQS, Spain
|
2020 | Award for 2nd best poster presentation (4th WG meeting - Final status of WG activities within the MuTaLig COST Action (CA15135),
2020, March 5th-6th, Izmir, Turkey)
Ege Üniversitesi Izmir Arastirma ve Uygulama Merkezi, Turkey
|
2020 | Best award for oral presentation (4th WG meeting - Final status of WG activities within the MuTaLig COST Action (CA15135),
2020, March 5th-6th, Izmir, Turkey)
Ege Üniversitesi Izmir Arastirma ve Uygulama Merkezi, Turkey
|
Title
2021 | Award of excellence from the Paul Ehrlich MedChem Euro-PhD in Medicinal Chemistry
Università degli Studi Magna Graecia di Catanzaro, Italy
|
2020 | European Doctorate
Universidade do Porto Faculdade de Farmácia, Portugal
|
Other distinction
2022 | Mobility grant, funded by project H2020-MSCA-RISE-2016-734719
European Commission Directorate-General for Research and Innovation, Belgium
|
2020 | Conference grant to attend the 4th WG meeting - Final status of WG activities within the MuTaLig COST Action
European Cooperation in Science and Technology, Belgium
|
2019 | Conference Grant for Early Career Investigators (ECI) and PhD students from Inclusiveness Target Countries (ITC)
European Cooperation in Science and Technology, Belgium
|
2018 | Full grant, CA15135 Multi-Targeting Biophysical Training School, 2nd edition (EU)
European Cooperation in Science and Technology, Belgium
|
2018 | Conference grant to attend the 2nd WG meeting - Status of WG activities of the MuTaLig COST Action (CA15135)
European Cooperation in Science and Technology, Belgium
|