Melanie Pruvost (481F-A760-D37E)

Curriculum Vitae

Melanie Pruvost

Mélanie Pruvost is a paleogenetician, specialized in the study of human and animal populations using ancient DNA. Coordinator of the ANR Ancestra project (2015-2020), she was particularly interested in the population of the territory that corresponds to present-day France from the Mesolithic to the High Middle Ages. She is also working on various projects in collaboration with other researchers to study the evolution of the genetic diversity of certain animal species under anthropogenic pressure, particularly during the process of domestication.

Identification

Personal identification

Full name: Melanie Pruvost

Citation names

Pruvost, Melanie

Author identifiers

Ciência ID: 481F-A760-D37E
ORCID iD: 0000-0001-7824-2155

Knowledge fields

Natural sciences - Biological Sciences

Languages

Language	Speaking	Reading	Writing	Listening	Peer-review
French (Mother tongue)
English	Advanced (C1)	Advanced (C1)	Advanced (C1)	Advanced (C1)	Advanced (C1)

Projects

Grant

	Designation	Funders
2015/12 - 2019/06	ANCESTRA, Genetic characterization of ancestral French populations using ancient DNA ANR-15-CE27-0001 Principal investigator	Agence nationale de la recherche Concluded

Other

	Designation	Funders
2021/04 - Current	Tracking the evolution of human craniodental structures – GenoMorph ANR-20-CE12-0018 Researcher Université de Bordeaux, France	Ongoing
2019 - Current	GENETIX LAbEx LaScArBx Supervisor	Ongoing
2019 - Current	LANGPOP Labex Archimede Researcher

Outputs

Publications

Journal article

Mélanie Pruvost. "7000 years of the peopling of present-day France revealed by paleogenomics". TheScienceBreaker (2020): https://hal.archives-ouvertes.fr/hal-03093828.
10.25250/thescbr.brk443
Samantha Brunel; E. Andrew Bennett; Laurent Cardin; Damien Garraud; Hélène Barrand Emam; Alexandre Beylier; Bruno Boulestin; et al. "Ancient genomes from present-day France unveil 7,000 years of its demographic history". Proceedings of the National Academy of Sciences of the United States of America (2020): https://hal.archives-ouvertes.fr/hal-03039135.
10.1073/pnas.1918034117
Fages A; Hanghøj K; Khan N; Gaunitz C; Seguin-Orlando A; Leonardi M; McCrory Constantz C; et al. "Tracking Five Millennia of Horse Management with Extensive Ancient Genome Time Series.". Cell (2019): http://europepmc.org/abstract/med/31056281.
10.1016/j.cell.2019.03.049
Librado P; Gamba C; Gaunitz C; Der Sarkissian C; Pruvost M; Albrechtsen A; Fages A; et al. "Ancient genomic changes associated with domestication of the horse.". Science (New York, N.Y.) (2017): http://europepmc.org/abstract/med/28450643.
10.1126/science.aam5298
Bennett EA; Champlot S; Peters J; Arbuckle BS; Guimaraes S; Pruvost M; Bar-David S; et al. "Taming the late Quaternary phylogeography of the Eurasiatic wild ass through ancient and modern DNA.". PloS one (2017): http://europepmc.org/abstract/med/28422966.
10.1371/journal.pone.0174216
Cruz-Dávalos DI; Llamas B; Gaunitz C; Fages A; Gamba C; Soubrier J; Librado P; et al. "Experimental conditions improving in-solution target enrichment for ancient DNA.". Molecular ecology resources (2016): http://europepmc.org/abstract/med/27566552.
10.1111/1755-0998.12595
Guimaraes S; Pruvost M; Daligault J; Stoetzel E; Bennett EA; Côté NM; Nicolas V; et al. "A cost-effective high-throughput metabarcoding approach powerful enough to genotype ~44 000 year-old rodent remains from Northern Africa.". Molecular ecology resources (2016): http://europepmc.org/abstract/med/27374145.
10.1111/1755-0998.12565
Côté NM; Daligault J; Pruvost M; Bennett EA; Gorgé O; Guimaraes S; Capelli N; et al. "A New High-Throughput Approach to Genotype Ancient Human Gastrointestinal Parasites.". PloS one (2016): http://europepmc.org/abstract/med/26752051.
10.1371/journal.pone.0146230
Gorgé O; Bennett EA; Massilani D; Daligault J; Pruvost M; Geigl EM; Grange T. "Analysis of Ancient DNA in Microbial Ecology.". Methods in molecular biology (Clifton, N.J.) (2016): http://europepmc.org/abstract/med/26791510.
10.1007/978-1-4939-3369-3_17
Ludwig A; Reissmann M; Benecke N; Bellone R; Sandoval-Castellanos E; Cieslak M; Fortes GG; et al. "Twenty-five thousand years of fluctuating selection on leopard complex spotting and congenital night blindness in horses.". Philosophical transactions of the Royal Society of London. Series B, Biological sciences (2015): http://europepmc.org/abstract/med/25487337.
10.1098/rstb.2013.0386
Ludwig A; Pruvost M; Bellone R; Benecke N; Sandoval-Castellanos E; Morales-Muñiz A; O'Connor T; Reissmann M; Hofreiter M. "Reply to Bar-Oz and Lev-Yadun: Horse colors in time and space.". Proceedings of the National Academy of Sciences of the United States of America (2012): http://europepmc.org/abstract/PMC/PMC3356605.
10.1073/pnas.1203187109
Pruvost M; Bellone R; Benecke N; Sandoval-Castellanos E; Cieslak M; Kuznetsova T; Morales-Muñiz A; et al. "Genotypes of predomestic horses match phenotypes painted in Paleolithic works of cave art.". Proceedings of the National Academy of Sciences of the United States of America (2011): http://europepmc.org/abstract/med/22065780.
10.1073/pnas.1108982108
Pruvost M; Reissmann M; Benecke N; Ludwig A. "From genes to phenotypes - evaluation of two methods for the SNP analysis in archaeological remains: pyrosequencing and competitive allele specific PCR (KASPar).". Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft (2011): http://europepmc.org/abstract/med/22154270.
10.1016/j.aanat.2011.10.007
Cieslak M; Pruvost M; Benecke N; Hofreiter M; Morales A; Reissmann M; Ludwig A. "Origin and history of mitochondrial DNA lineages in domestic horses.". PloS one (2010): http://europepmc.org/abstract/med/21187961.
10.1371/journal.pone.0015311
Champlot S; Berthelot C; Pruvost M; Bennett EA; Grange T; Geigl EM. "An efficient multistrategy DNA decontamination procedure of PCR reagents for hypersensitive PCR applications.". PloS one (2010): http://europepmc.org/abstract/med/20927390.
10.1371/journal.pone.0013042
Ludwig A; Pruvost M; Reissmann M; Benecke N; Brockmann GA; Castaños P; Cieslak M; et al. "Coat color variation at the beginning of horse domestication.". Science (New York, N.Y.) (2009): http://europepmc.org/abstract/med/19390039.
10.1126/science.1172750
Mélanie Pruvost; Reinhard Schwarz; Virginia Bessa Correia; Sophie Champlot; Thierry Grange; Eva-Maria Geigl. "DNA diagenesis and palaeogenetic analysis : Critical assessment and methodological progress". Palaeogeography, Palaeoclimatology, Palaeoecology (2008): https://hal.archives-ouvertes.fr/hal-00326916.
10.1016/j.palaeo.2008.03.041
Mélanie Pruvost; Reinhard Schwarz; Virginia Bessa Correia; Sophie Champlot; Séverine Braguier; Nicolas Morel; Yolanda Fernandez-Jalvo; Thierry Grange; Eva-Maria Geigl. "Freshly excavated fossil bones are best for amplification of ancient DNA.". Proceedings of the National Academy of Sciences of the United States of America (2007): https://hal.archives-ouvertes.fr/hal-00124469.
10.1073/pnas.0610257104
Mélanie Pruvost; Thierry Grange; Eva-Maria Geigl. "Minimizing DNA contamination by using UNG-coupled quantitative real-time PCR on degraded DNA samples: application to ancient DNA studies.". Biotechniques (2005): https://hal.archives-ouvertes.fr/hal-00069259.

Report

Muriel Gandelin; Frédéric Chandevau; Jean Guilaine; Christophe Ranché; Jean Vaquer; Caroline Hamon; Fabien Convertini; et al. 2018. Milieu et Peuplement en Languedoc occidental du Néolithique au Bronze ancien Occitanie, Projet collectif de Recherches. https://hal-univ-tlse2.archives-ouvertes.fr/hal-02025738.

Other

Other output

Taming the Late Quaternary phylogeography of the Eurasiatic wild ass through ancient and modern DNA. 2016. Bennett EA; Champlot S; Peters J; Arbuckle BS; Guimaraes S; Pruvost M; Bar-David S; et al. http://europepmc.org/abstract/PPR/PPR27155.
10.1101/090928

Activities

Oral presentation

	Presentation title	Event name Host (Event location)
2019/10/03	Le projet Ancestra: Archéologie des migrations.	L'hospitalité défiée par les migrations conférence du Chateau de Goutelas. entre culturel de rencontre, Goutelas (France)
2019/01/23	De la couleur de la robe des chevaux à l'évolution des populations humaines: illustration des études phénotypiques basées sur l'ADN ancien .	Société d'Anthropologie de Paris (France)
2018/11/29	Qui sont les gens du début du Bronze final dans le sud-est du bassin parisien?	Troisièmes Rencontres Nord-Sud de Préhistoire récente (Lyon, France)
2018/11	Diversité génétique des populations néolithiques françaises : aperçu des premiers résultats du projet ANCESTRA.	Morts néolithiques, Table ronde de l’Adreuc (Carcassone, France)
2018/06/04	Paleogenomics of a French population, from the Neolithic to the Bronze Age.	XVIII° CONGRES UISPP (Paris, France)
2016/12/07	Ancient DNA bares its teeth : What ancient calculus can tell us about past populations?	DNA POLYMORPHISMS IN HUMAN POPULATIONS Musée de l'Homme (Paris, France)
2014/08/27	aMPlex-Torrent : a powerful and economical approach to study past-biodiversity.	The Fifth International Symposium on Biomolecular Archaeology, (Basel, Switzerland)
2014/03/26	High-throughput studies of the past biodiversity.	ICAZ working group Faculdade de Ciências da Universidade de Lisboa (Lisboa, Portugal)
2010/09/08	Nuclear ancient DNA draws picture of wild and early domesticated horses.	The Fourth International Symposium on Biomolecular Archaeology (Copenhagen, Denmark)

Supervision

	Thesis Title Role	Degree Subject (Type) Institution / Organization
2019 - Current	Migrations et fonctionnement des communautés de la transition Néolithique final-Âge du Bronze ancien en Europe de l’Ouest : apport de la Paléogénomique Supervisor	Université de Bordeaux, France
2017 - 2019	Study of the microbiome evolution on ancient human populations. Supervisor	Institute Jacques Monod, France
2014 - 2015	Hybridization-based target enrichment coupled to next generation sequencing to genotype ancient individuals Supervisor	PhD (PhD) Institute Jacques Monod, France
2013 - 2014	Génotypage à Haut-Débit d’ossements humains anciens par PCR multiplex Co-supervisor	Institute Jacques Monod, France
2007 - 2009	Coat colours and mitochondrial lineages of ancient horses to document domestication Co-supervisor	Freie Universität Berlin Angewandte Genetik, Germany