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Félix Carvalho, PharmD (1990), PhD (1998), is Full Professor of Toxicology, at the Laboratory of Toxicology, Department of Biological Sciences, Faculty of Pharmacy at University of Porto (FFUP), and researcher of the Research Unit on Applied Molecular Biosciences (UCIBIO) at REQUIMTE, Portugal. He is presently Vice-director of UCIBIO, President of the Scientific Council of FFUP, President of the Portuguese Society of Pharmacology, and President-elect of EUROTOX (Association of European Toxicologists and European Societies of Toxicology). Félix Carvalho is also European Expert of the European Medicines Agency (EMA), Member of the Committee for Evaluation of Medicines at the National Authority of Medicines and Health Products, I.P. (INFARMED), member of the Nanomaterials Expert Group (NMEG) of the European Chemicals Agency (ECHA), and participates in the editorial board of several scientific journals. His main area of research is Toxicology, with a special interest in Mechanistic Toxicology. During the past 30 years, Félix Carvalho co-authored over 400 scientific articles / book chapters, and is co-editor of two Books in the area of Toxicology: ¿Toxicologia Forense¿ (ISBN: 9789896930455) and ¿Toxicologia Fundamental¿ (ISBN: 9789896930455).
Identification

Personal identification

Full name
Félix Dias Carvalho
Gender
Male

Citation names

  • Carvalho, Félix
  • Dias Carvalho, Félix

Author identifiers

Ciência ID
491E-09B9-DBED
ORCID iD
0000-0003-3858-3494
Google Scholar ID
https://scholar.google.com/citations?hl=pt-PT&user=aPYy34MAAAAJ
Researcher Id
D-4914-2013
Scopus Author Id
57205357422

Email addresses

  • felixdc@ff.up.pt (Professional)

Telephones

Telephone
  • 220428600 (Professional)

Addresses

  • Rua de Jorge Viterbo Ferreira nº. 228, 4050-313, Porto , Porto , Portugal (Professional)

Websites

Knowledge fields

  • Medical and Health Sciences - Basic Medicine - Toxicology
  • Medical and Health Sciences - Basic Medicine - Pharmacology and pharmacy
  • Medical and Health Sciences - Health Sciences - Substance Abuse

Languages

Language Speaking Reading Writing Listening Peer-review
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
French Beginner (A1) Advanced (C1) Beginner (A1) Beginner (A1)
Portuguese Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Spanish; Castilian Advanced (C1) Advanced (C1) Beginner (A1) Advanced (C1)
Education
Degree Classification
2003/12/10
Concluded
Chemical Sciences (Título de Agregado)
Universidade do Porto Faculdade de Farmácia, Portugal
Aproved by unanimity
1998
Concluded
Félix Carvalho (Doutoramento)
Major in Toxicology
Universidade do Porto, Portugal
"The Toxicity of Amphetamines. In Vitro and In Vivo studies" (THESIS/DISSERTATION)
1990/05/15
Concluded
Pharmaceutical Sciences (Licenciatura)
Major in Branch A - Communitary and Hospital Pharmacy
Universidade do Porto Faculdade de Farmácia, Portugal
15 valores
Affiliation

Science

Category
Host institution
Employer
1988/10/01 - 1990/10/01 Contracted Researcher (Research) Universidade do Porto Faculdade de Farmácia, Portugal
Universidade do Porto Faculdade de Farmácia, Portugal

Teaching in Higher Education

Category
Host institution
Employer
2012/03/21 - Current Full Professor (University Teacher) Universidade do Porto Faculdade de Farmácia, Portugal
Universidade do Porto Faculdade de Farmácia, Portugal
2016 - 2019 Full Professor (University Teacher) Universidade do Porto, Portugal
2016 - 2019 Full Professor (University Teacher) Universidade do Porto, Portugal
2013 - 2016 Full Professor (University Teacher) Universidade do Porto Faculdade de Farmácia, Portugal
2013 - 2016 Full Professor (University Teacher) Universidade do Porto Faculdade de Farmácia, Portugal
2005/02/28 - 2012/03/21 Associate Professor (University Teacher) Universidade do Porto Faculdade de Farmácia, Portugal
Universidade do Porto Faculdade de Farmácia, Portugal
1998/05/29 - 2005/02/28 Assistant Professor (University Teacher) Universidade do Porto Faculdade de Farmácia, Portugal
Universidade do Porto Faculdade de Farmácia, Portugal
1994/02/22 - 1998/05/29 Assistant (University Teacher) Universidade do Porto Faculdade de Farmácia, Portugal
Universidade do Porto Faculdade de Farmácia, Portugal
1991/12/04 - 1994/02/22 Trainee Assistant (University Teacher) Universidade do Porto Faculdade de Farmácia, Portugal
Universidade do Porto Faculdade de Farmácia, Portugal
1990/03/20 - 1991/12/04 Tutor (University Teacher) Universidade do Porto Faculdade de Farmácia, Portugal
Universidade do Porto Faculdade de Farmácia, Portugal

Other Careers

Category
Host institution
Employer
1990/03/20 - 1991/05/30 Assessor Superior (Técnico Superior de Saúde - Farmácia) Unidade Hospitalar de Santo Tirso, Portugal
Unidade Hospitalar de Santo Tirso, Portugal

Positions / Appointments

Category
Host institution
Employer
2018/10/01 - 2024/05/01 President of the Scientific Council Universidade do Porto Faculdade de Farmácia, Portugal
Universidade do Porto Faculdade de Farmácia, Portugal
2016 - 2019 Vice-President of the Scientific Council Universidade do Porto, Portugal
2016 - 2019 Conselho científico/técnico-científico ou orgão correspondente Universidade do Porto, Portugal
2013 - 2016 Member of the Scientific Council Universidade do Porto Faculdade de Farmácia, Portugal
2013 - 2016 Conselho geral ou orgão correspondente Universidade do Porto Faculdade de Farmácia, Portugal
Projects

Grant

Designation Funders
2021/01 - 2025/12 Instituto para a Saúde e a Bioeconomia
168280UID
Fundação para a Ciência e a Tecnologia
2022/01 - 2023/12 Indução da sinaptogénese e crescimento de neurites pelo metilfenidato e anfetamina na perturbação de hiperatividade e défice de atenção PHDA
168881PRJ
Fundação para a Ciência e a Tecnologia
2019/12 - 2023/11 Desenvolvimento de novos inibidores do osteossarcoma invasivo baseados em derivados da fisetina
150430PRJ
Fundação para a Ciência e a Tecnologia
2018/07 - 2022/03 Avaliação dos efeitos moduladores de canabinóides sintéticos sobre desenvolvimento neuronal
150770PRJ
Fundação para a Ciência e a Tecnologia
2018/06 - 2022/02 2-Estirilcromonas no tratamento da artrite reumatoide: possível alternativa terapêutica?
150440PRJ
Fundação para a Ciência e a Tecnologia
2018/06 - 2022/02 Estudos interdisciplinares in silico, de síntese orgânica, in vitro e in vivo para desenvolvimento de novas estruturas de flavonoides com atividade antidiabética
150428PRJ
Fundação para a Ciência e a Tecnologia
2018/06 - 2021/12 Uso de flavonoides na profilaxia dos efeitos pro-inflamatórios intestinais de nanopartículas de prata
150435PRJ
Fundação para a Ciência e a Tecnologia
2016/07 - 2019/12 Os anticancerígenos como venenos cardíacos: será a bioactivação metabólica ou a promoção do envelhecimento a conexão para a cardiotoxicidade dos fármacos anticancerígenos?
148213PRJ
Fundação para a Ciência e a Tecnologia
2016/06 - 2019/12 Desenvolvimento de antídotos para intoxicações por Amanita phalloides, do in silico ao doente intoxicado
148215PRJ
Fundação para a Ciência e a Tecnologia
2016/01 - 2018/12 Development of antidotes for Amanita phalloides intoxications, from in silico to the intoxicated patient
PTDC/DTP-FTO/4973/2014
Universidade do Porto Faculdade de Desporto, Portugal

Universidade do Porto Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares, Portugal

Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal
Ministério da Ciência Tecnologia e Ensino Superior

Fundação para a Ciência e a Tecnologia
Concluded
2011/04 - 2014/09 Interacção da aspirina com fármacos anti-hipertensores: impacto no controlo da pressão arterial e no stresse oxidativo, inflamação e activação do sistema renina-angiotensina renal.
114166PRJ
Fundação para a Ciência e a Tecnologia
2011/01 - 2014/06 Ensaios pré-clinicos com a vacina constituida pela GAPDH de Streptococcus agalactiae
111387PRJ
Fundação para a Ciência e a Tecnologia
2010/03 - 2013/11 IMPLICATIONS OF AMPHETAMINE PSYCHOSTIMULANTS ABUSE IN BRAIN AGING
PTDC/SAU-FCF/102958/2008
Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Universidade de Coimbra, Portugal

Universidade de Coimbra Faculdade de Medicina, Portugal

Associação para a Inovação e Desenvolvimento da FCT, Portugal

Universidade do Porto, Portugal

Universidade do Porto Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares, Portugal

Universidade de Coimbra, Portugal
Fundação para a Ciência e a Tecnologia, I.P.

Fundação para a Ciência e a Tecnologia

Ministério da Ciência Tecnologia e Ensino Superior
Concluded
2010/03 - 2013/11 CONSEQUÊNCIAS DO CONSUMO RECREATIVO DE PSICOESTIMULANTES ANFETAMINICOS NO ENVELHECIMENTO CEREBRAL
102958PRJ
Fundação para a Ciência e a Tecnologia
2010/06 - 2013/06 O papel da cascata de sinalização do Nrf2/ARE na sobrecarga do ferro. Resposta adaptativa ao stresse oxidativo como um factor modificador da doença na hemocromatose hereditária associada ao gene HFE
101177PRJ
Fundação para a Ciência e a Tecnologia
2011/01 - 2012/12 Projecto Estratégico - LA 6 - 2011-2012
123363UID
Fundação para a Ciência e a Tecnologia
2009/01 - 2011/12 Proteomic study of salivary disorders induced by diabetes
PTDC/QUI/72683/2006
72683PRJ
Universidade de Aveiro, Portugal

Universidade de Aveiro Unidade de Investigação de Química Orgânica Produtos Naturais e Agroalimentares, Portugal

Universidade do Porto Faculdade de Medicina, Portugal

Universidade do Porto Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares, Portugal

Universidade do Porto Faculdade de Desporto, Portugal

Cooperativa de Ensino Superior Politécnico e Universitário, Portugal

Universidade de Aveiro, Portugal

Universidade do Porto Faculdade de Medicina, Portugal

Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal

Cooperativa de Ensino Superior Politécnico e Universitário CRL, Portugal
Stichting Weten

Fundação para a Ciência e a Tecnologia
Concluded
2005/06 - 2008/06 Estudos farmacogenéticos para avaliação da influência do metabolismo na expressão da toxicidade de derivados anfetamínicos usados correntemente como drogas de abuso
57187PRJ
Fundação para a Ciência e a Tecnologia
2005/10 - 2007/12 Stress oxidativo na Doença Cardíaca: acção das catecolaminas
55849PRJ
Fundação para a Ciência e a Tecnologia
2003/01 - 2005/12 Amphetamines and physical exercise. An hazardous combination?
Provided by PTCRIS: 43562
Ministério da Ciência Tecnologia e Ensino Superior
2000/12 - 2003/11 Hepatotoxicity and cardiotoxicity studies of methylenedioxymetamphetamine and its metabolites in Wistar Rats.
Provided by PTCRIS: 36099
Ministério da Ciência Tecnologia e Ensino Superior

Contract

Designation Funders
2020 - Current The Holy Grail of Forensic Sciences: assessment of biochemical alterations and RNA degradation profile in cadaver to estimate the postmortem interval
PTDC/BIA-BQM/6669/2020
Instituto Universitário de Ciências da Saúde, Portugal
Associação para a Inovação e Desenvolvimento da FCT
Cancelled
2023/01/01 - 2026/01/01 Safety profile and therapeutic potential of psilocybin and other Psilocybe mushrooms¿ phytochemicals for the treatment of depression: A preclinical study
2022.02020.PTDC
Instituto Universitário de Ciências da Saúde, Portugal
Associação para a Inovação e Desenvolvimento da FCT
2021/01/01 - 2025/12/31 Institute for Health and Bioeconomy
LA/P/0140/2020
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal

Universidade de Lisboa Instituto de Bioengenharia e Biociências, Portugal

Universidade NOVA de Lisboa, Portugal

INESC Microsistemas e Nanotecnologias, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Associação para a Inovação e Desenvolvimento da FCT, Portugal

Unidade de Ciências Biomoleculares Aplicadas, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2022/01/01 - 2023/12/31 Methylphenidate and amphetamine-induced synaptogenesis and neurite outgrowth in attention deficit hyperactivity disorder ADHD
EXPL/MED-FAR/0203/2021
Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal

Universidade do Porto Faculdade de Medicina, Portugal

Charité Universitätsmedizin Berlin, Germany

Unidade de Ciências Biomoleculares Aplicadas, Portugal

Universidade do Porto Faculdade de Medicina, Portugal

Centro de Investigação em Tecnologias e Serviços de Saúde, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2020/01/01 - 2023/12/31 Applied Molecular Biosciences Unit
UIDB/04378/2020
UIDP/04378/2020
Universidade NOVA de Lisboa, Portugal

Unidade de Ciências Biomoleculares Aplicadas, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Associação para a Inovação e Desenvolvimento da FCT, Portugal

Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal

Universidade do Porto, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2019/12/01 - 2023/11/30 Development of new inhibitors of invasive osteosarcoma based on fisetin derivatives
PTDC/MED-QUI/29243/2017
Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Universidade de Aveiro, Portugal

Universidade do Porto, Portugal

Universidade de Aveiro, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2019/03/01 - 2022/09/30 Neurotoxicity De-Risking in Preclinical Drug Discovery
821528
European Commission
Concluded
2018/06/01 - 2022/02/28 2-Styrylchromones in the treatment of rheumatoid arthritis: a promising therapeutic alternative?
PTDC/MED-QUI/29253/2017
Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Universidade de Aveiro, Portugal

Universidade do Porto, Portugal

Universidade de Aveiro, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2018/07/01 - 2021/12/31 Assessment of the modulatory effects of Synthetic CANNabinoids on NEUROnal development
PTDC/SAU-TOX/29584/2017
Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Universidade do Porto, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2018/06/01 - 2021/12/31 Use of flavonoids in the prophylaxis of intestinal pro-inflammatory effects of silver nanoparticles
PTDC/NAN-MAT/29248/2017
Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Universidade do Porto, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2018/06/01 - 2021/05/31 Interdisciplinary in silico, organic synthesis, in vitro, and in vivo studies towards new anti-diabetic flavonoid scaffolds
PTDC/MED-QUI/29241/2017
Universidade de Aveiro, Portugal

Universidade do Porto, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Universidade de Aveiro, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2019/01/01 - 2019/12/31 Unidade de Ciências Biomoleculares Aplicadas
UID/Multi/04378/2019
154717UID
Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2019/01/01 - 2019/12/31 Applied Molecular Biosciences Unit
UID/Multi/04378/2019
Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Unidade de Ciências Biomoleculares Aplicadas, Portugal

Associação para a Inovação e Desenvolvimento da FCT, Portugal

Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal

Universidade do Porto Faculdade de Ciências, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2016/07/11 - 2019/12/31 Poisoning the heart with anticancer drugs: is metabolic bioactivation or aging promotion the link to the cardiotoxicity of anticancer drugs?
PTDC/DTP-FTO/1489/2014
Universidade do Porto Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares, Portugal

Universidade do Porto Faculdade de Desporto, Portugal

Universidade de Aveiro, Portugal

Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal

Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal

Universidade de Aveiro, Portugal
Fundação para a Ciência e a Tecnologia

Ministério da Ciência Tecnologia e Ensino Superior
Concluded
2011/04/01 - 2014/09/30 Interaction of aspirin with antihypertensive drugs - impact on renal oxidative stress, inflammation, local renin-angiotensin system activation and blood pressure control
PTDC/SAU-TOX/114166/2009
Universidade do Porto Faculdade de Medicina, Portugal

Universidade do Porto Centro de Farmacologia e Biopatologia Química, Portugal

Universidade do Porto Faculdade de Farmácia, Portugal

Universidade do Porto Faculdade de Medicina, Portugal
Fundação para a Ciência e a Tecnologia

Ministério da Ciência Tecnologia e Ensino Superior

Stichting Weten
Concluded
2011/01/01 - 2014/06/30 Pre-clinical assays of a GAPDH-based vaccine against Group B Streptococcus infection
PTDC/SAU-MIC/111387/2009
Instituto de Biologia Molecular e Celular, Portugal

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Universidade do Porto Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares, Portugal

Universidade de Lisboa Faculdade de Farmácia, Portugal

Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal
Fundação para a Ciência e a Tecnologia

Stichting Weten

Fundação para a Ciência e a Tecnologia, I.P.
Concluded
2010/06/01 - 2013/06/30 A role for Nrf2/ARE cytoprotective signalling in iron overload. Adaptive response to oxidative stress as a disease modifier in HFE-associated hereditary hemochromatosis.
PTDC/SAU-FCF/101177/2008
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal

Instituto de Biologia Molecular e Celular, Portugal

Universidade do Porto Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares, Portugal

Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
Fundação para a Ciência e a Tecnologia

Fundação para a Ciência e a Tecnologia, I.P.

Stichting Weten
Concluded
2011/01/01 - 2012/12/31 Strategic Project - LA 6 - 2011-2012
PEst-C/EQB/LA0006/2011
Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Universidade de Lisboa Instituto Dom Luiz, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2006/12/01 - 2008/10/31 CHOLINEOMANIA - Which kind of metal contamination is efficiently detected by cholinesterase from the marine shrimp Paleamon serratus?
POCI/MAR/58244/2004
58244PRJ
Universidade do Porto Faculdade de Desporto, Portugal

Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal

Centro de Ciências do Mar, Portugal

Universidade do Porto Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares, Portugal

Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
Fundação para a Ciência e a Tecnologia

Fundação para a Ciência e a Tecnologia, I.P.

Stichting Weten
Concluded
2005/06/01 - 2008/06/30 Pharmacogenetic studies on the role of metabolism on the toxicity of amphetaminic designer drugs of abuse
POCI/SAU-FCF/57187/2004
REQUIMTE LAQV Porto, Portugal

Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal

Universidade do Porto Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares, Portugal
Fundação para a Ciência e a Tecnologia

Fundação para a Ciência e a Tecnologia, I.P.

Stichting Weten
Concluded
2005/10/01 - 2007/12/31 OXIDATIVE STRESS IN HEART DISEASE: ROLE OF CATECHOLAMINES
POCI/SAU-OBS/55849/2004
REQUIMTE LAQV Porto, Portugal

Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal

Universidade de Aveiro, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Universidade do Porto Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares, Portugal

Universidade de Aveiro, Portugal

Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia

Stichting Weten

Ministério da Ciência Tecnologia e Ensino Superior
Concluded
Outputs

Publications

Book chapter
  1. Proença, Carina; Freitas, Marisa; Rocha, Silvia; Ferreira de Oliveira, José Miguel P.; Carvalho, Félix; Eduarda Fernandes. "Unraveling the complex mechanisms involved in obesity pathophysiology as potential targets for environmental chemicals". 2024.
    Under revision
  2. Costa, Vera M; Carvalho, Félix; Seabra, Vítor. "Metais e Metalóides". In Toxicologia Alimentar, edited by Oliveira, Nuno G.; Carvalho, Félix; Dinis, Ricardo. Portugal: Lidel, 2023.
    Submitted
  3. Barbosa, Daniel José; Carvalho, Félix; Carmo, Helena. "The mitochondrial disruption as a contributing factor for the neurotoxicity of amphetamines". In Mitochondrial Intoxication. United States: Elsevier, 2023.
    Published
  4. Barbosa, Daniel José; Carvalho, Félix; Carmo, Helena. "Mitochondrial disruption as a contributing factor for the neurotoxicity of amphetamines". In Mitochondrial Intoxication, 271-297. Elsevier, 2023.
    Published • 10.1016/b978-0-323-88462-4.00014-6
  5. Adelaide Sousa; Carvalho, Félix; Eduarda Fernandes; Freitas, Marisa; Sousa, A.; Carvalho, F.; Fernandes, E.; Freitas, M.. "Applications of Silver Nanoparticles in Daily Life". In Applications of Silver Nanoparticles, 151-169. Nova Science Publishers, 2023.
    Accepted
  6. Silva, João Pedro; Carvalho, Félix. Corresponding author: Silva, João Pedro. "Chapter 10.5-2: Nuevas sustâncias psicoativas en patologia dual". In Patología dual: Recomendaciones para la mejora de la calidad del proceso asistencial. Editorial Medica Panamericana (Madrid, Spain), 2023.
    Published
  7. Silva, João Pedro; Carmo, Helena; Carvalho, Félix. "Chapter 67-1: Synthetic Cannabinoids and Neurodevelopment (SENIOR/CORRESPONDING AUTHOR)". In Handbook of Substance Misuse and Addictions, edited by Patel, VB; Preedy, VR. Springer Nature, 2022.
    Accepted
  8. Roque Bravo, Rita; Silva, João Pedro; Carmo, Helena; Carvalho, Félix; Dias da Silva, Diana; Bravo, R.R.; Silva, J.P.; et al. "The Toll of Benzofurans in the Context of Drug Abuse". In Handbook of Substance Misuse and Addictions, 1-24. Springer International Publishing, 2022.
    10.1007/978-3-030-67928-6_168-1
  9. Silva, J.P.; Carmo, H.; Carvalho, F.. "Synthetic Cannabinoids and Neurodevelopment". 1321-1342. 2022.
  10. Lucas, M.; Freitas, M.; Carvalho, F.; Fernandes, E.; Ribeiro, D.; Lucas, Mariana; Freitas, Marisa; et al. "Antioxidant and Pro-oxidant Activities of Carotenoids". In Reference Series in Phytochemistry, 123-148. Springer International Publishing, 2022.
    Published • 10.1007/978-3-030-78160-6_4
  11. Capela, João Paulo; Carvalho, Félix. "Tratamiento farmacológico del trastorno por consumo de cannabis y las condiciones associadas - Farmacoterapias para la dependencia y abstinencia de cannabis: revisión de los ensayos clínicos aleatorizados". In GUÍA CLÍNICA DE CANNABIS, edited by Hugo López Pelayo; María Teresa Cortés Tomás, 196-215. Barcelona, Spain: Socidrogalcohol, 2021.
    Published
  12. Costa, Vera M; Carvalho, Ana Rita; Capela, João Paulo; Carvalho, Félix; Costa, V.M.; Carvalho, A.R.D.; Capela, J.P.; Carvalho, F.. Corresponding author: Costa, Vera M. "Chemobrain". In Toxicological Risk Assessment and Multi-System Health Impacts from Exposure, edited by Aristides Tsatsakis, 62-72. Netherlands: Elsevier Editions, 2021.
    Published
  13. Rui Malheiro; Telma Gomes; Carmo, Helena; Carvalho, Félix; João Pedro Silva; Malheiro, R.F.; Gomes, T.M.; et al. "Cannabinoids and psychosis: current challenges of mechanistic toxicology.". In Toxicological risk assessment and multi-system health impacts from exposure, edited by AM Tsatsakis; G Tsatsakis; VE Karzi; Tsatsakis, A, 601-615. Amsterdam, Netherlands: Academic Press, Elsevier Inc, 2021.
    Published
  14. Bravo, Rita Roque; João Pedro Silva; Carmo, Helena; Carvalho, Félix; Diana Dias da Silva. "Chapter 168-1: The Toll of Benzofurans in the Context of Drug Abuse". In Handbook of Substance Misuse and Addictions, edited by VB Patel; VR Preedy. Springer Nature, 2021.
    In press
  15. Ribeiro, D.; Freitas, M.; de Oliveira, J.M.P.F.; Corvo, M.L.; Carvalho, F.D.; Fernandes, E.. "Inflammatory pathways and in vivo studies of inflammatory bowel disease". 1-23. 2021.
  16. Calina, D.; Carvalho, F.; Docea, A.O.. "Toxicity of psychedelic drugs". 545-556. 2021.
  17. Freitas, M.; de Oliveira, J.M.P.F.; Corvo, M.L.; Carvalho, F.; Fernandes, E.; Ribeiro, D.. "Insights on the potential preventive and healing effects of flavonoids in inflammatory bowel disease". 38-66. 2021.
  18. Carvalho, Félix; Remião, F.; Soares, J.; Carvalho, F.. "Portugal". In Information Resources in Toxicology (Fifth Edition), Volume 2: the Global Arena., 413-417. Academic Press, 2020.
  19. Carvalho, Félix. "Mesenchymal stem cells for cutaneous healing". In Concepts and Applications of Stem Cell Biology. A Guide for Students. Springer, 2020.
  20. Barbosa, Daniel José; Capela, João Paulo; de Lourdes Bastos, Maria; Carvalho, Félix; Barbosa, D.J.; Capela, J.P.; De Lourdes Bastos, M.; Carvalho, F.. "Involvement of Mitochondrial Dysfunction on the Toxic Effects Caused by Drugs of Abuse and Addiction". In Mitochondrial Dysfunction Caused by Drugs and Environmental Toxicants, 487-508. John Wiley & Sons, Inc., 2018.
    10.1002/9781119329725.ch32
  21. Carvalho, Félix. "Introdução à Toxicologia: conceitos fundamentais". In Toxicologia Fundamental. Lidel, 2018.
  22. Carvalho, Félix. "Toxicocinética". In Toxicologia fundamental. Lidel, 2018.
  23. Carvalho, Félix. "O fígado como órgão-alvo da toxicidade dos xenobióticos". In Toxicologia fundamental. Lidel, 2018.
  24. Carvalho, Félix. "O pulmão como órgão-alvo da toxicidade dos xenobióticos". In Toxicologia fundamental. Lidel, 2018.
  25. Carvalho, Félix. "O coração como órgão-alvo da toxicidade dos xenobióticos". In Toxicologia Fundamental. Lidel, 2018.
  26. Carvalho, Félix. "O sistema nervoso como alvo da toxicidade dos xenobióticos". In Toxicologia Fundamental. Lidel, 2018.
  27. Carvalho, Félix. "O sistema endócrino como alvo da toxicidade dos xenobióticos". In Toxicologia Fundamental. Lidel, 2018.
  28. Carvalho, Félix. "O sangue como tecido-alvo da toxicidade dos xenobióticos". In Toxicologia Fundamental. Lidel, 2018.
  29. Carvalho, Félix. "Pro-inflammatory and toxic effects of silver nanoparticles". In Nanoparticles in Life Sciences and Biomedicine. Pan Stanford Publishing Pte. Ltd, 2018.
  30. Capela, João Paulo; Dinis-Oliveira, Ricardo Jorge; Bastos, Maria de Lourdes; Carvalho, Félix. "Toxicologia do sistema nervoso". In Toxicologia Fundamental, edited by Felix Dias Carvalho; Maria de Lourdes Bastos; Ricardo Dinis, 203-214. Portugal: Lidel, 2018.
    Published
  31. Carvalho, Félix. "Serotonina". In Neurociências. Lidel, 2017.
  32. Carvalho, Félix. "Farmacodinâmica das drogas e do álcool". In Sexo, drogas e cérebro. Edições Afrontamento, 2016.
  33. Barbosa, D.J.; Capela, J.P.; Bastos, M.L.; Carvalho, F.; Barbosa, J.S.; De Lourdes Bastos, M.; Carvalho, E.. "Mitochondrial Trails in the Neurotoxic Mechanisms of MDMA". 431-444. 2016.
  34. Barbosa, J.Joana; Faria, J.Juliana; Carvalho, F.Félix; Queirs, O.Odília; Moreira, R.Roxana; Dinis-Oliveira, R.J.. "Meconium as an alternative matrix in bioanalysis". In New Sampling Strategies in Toxicology and Therapeutic Drug Monitoring, 136-150. Future Science Book Series, 2015.
    Published • 10.4155/fseb2013.14.114
  35. Baltazar, Maria Teresa; Dinis-Oliveira, Ricardo Jorge; Bastos, Maria de Lourdes; Carvalho, Félix; Baltazar, MT; Ricardo Jorge Dinis Oliveira; Maria de Lourdes Bastos; Felix Carvalho. "Paraquat: Molecular Mechanisms of Neurotoxicity and its Relation with Autophagy". In Toxicity and Autophagy in Neurodegenerative Disorders, 159-170. Springer International Publishing, 2015.
    10.1007/978-3-319-13939-5_9
  36. Carvalho, Félix. "Introdução à Toxicologia Forense". In Toxicologia Forense, 1-8. 2015.
  37. Carvalho, Félix. "Recomendações Gerais para Colheita de Amostras Biológicas em Toxicologia Forense". In Toxicologia Forense, 103-108. Pactor, Edições de Ciências Sociais, Forenses e da Educação, 2015.
  38. Carvalho, Félix; Dinis-Oliveira, Ricardo Jorge; Vieira-Coelho, MA. "Introdução às Toxicodependências". In Toxicologia Forense, 131-140. Lisboa, Portugal: Pactor, Edições de Ciências Sociais, Forenses e da Educação, 2015.
    Published
  39. Carvalho, Félix. "Opióides". In Toxicologia Forense. Pactor, Edições de Ciências Sociais, Forenses e da Educação, 2015.
  40. Carvalho, Félix. "Anfetaminas e Derivados". In Toxicologia Forense. Edições de Ciências Sociais, Forenses e da Educação, 2015.
  41. Carvalho, Félix. "Pesticidas". In Toxicologia forense. Pactor, Edições de Ciências Sociais, Forenses e da Educação, 2015.
  42. Capela, J.P.; Bastos, M.L.; Carvalho, F.. "Ecstasy". In Encyclopedia of the Neurological Sciences, 1064-1067. Academic Press, 2014.
  43. Carvalho, F.; Carmo, H.; Guedes de Pinho, P.; Remião, F.; de Lourdes Bastos, M.; Carvalho, M.. "Mephedrone". In Encyclopedia of Toxicology, 194-196. Academic Press, 2014.
  44. Carvalho, Félix. "Tóxicos e intoxicações". In Terapêutica Medicamentosa e suas Bases Farmacológicas, 6ª edição, 812-821. 2014.
  45. Cunha-Oliveira, Teresa; Rego, Ana Cristina; Carvalho, Félix; Oliveira, Catarina R.; Teresa Cunha-Oliveira; Ana Cristina Rego; Félix Carvalho; et al. "Medical Toxicology of Drugs of Abuse". In Principles of Addiction, 159-175. Elsevier, 2013.
    10.1016/b978-0-12-398336-7.00017-6
  46. Carvalho, Félix. "A perícia em Toxicologia Forense: da suspeita à interpretação de resultados". In Ciências Forenses ao Serviço da Justiça, 159-188. PACTOR – Edições de Ciências Sociais, Forenses e da Educação, 2013.
  47. Marisa, Vera; Carvalho, Flix; Lourdes, Maria; Albuquerque, Rui; Carvalho, Mrcia; Remio, Fernando. "Adrenaline and Noradrenaline: Partners and Actors in the Same Play". In Neuroscience - Dealing With Frontiers. InTech, 2012.
    10.5772/36070
  48. Sousa, Teresa; Afonso, Joana; Carvalho, Flix; Albino-Teixeir, Antnio; Félix Carvalho. "Lipid Peroxidation and Antioxidants in Arterial Hypertension". In Lipid Peroxidation. InTech, 2012.
    10.5772/50346
  49. Valente, Maria João Portugal Couto; Carvalho, Félix; Bastos, Maria de Lourdes; Carvalho, Márcia; Guedes de Pinho, Paula; Valente, Maria João; de Lourdes Bastos, Maria; de Pinho, Paula Guedes. "Chromatographic Methodologies for Analysis of Cocaine and Its Metabolites in Biological Matrices". In Gas Chromatography - Biochemicals, Narcotics and Essential Oils, 163-163. InTech, 2012.
    Published • 10.5772/32225
  50. Carvalho, Félix. "Anti-inflammatory, antioxidant and antidiabetic plant compounds". In Biochemical Targets of Plant Bioactive Compounds, 595-657. CRC Press, 2003.
    10.1201/9780203013717.ch14
  51. Valentao, P; Fernandes, E; Carvalho, F; Andrade, PB; Seabra, RM; Bastos, ML; Pfannhauser, W; Fenwick, GR; Khokhar, S. "Antioxidant activity of Hypericum androsaemum infusion". 363-365. 2001.
  52. Waterfield, C.J.; Carvalho, F.; Timbrell, J.A.; Waterfield CJ; Carvalho F; Timbrell JA; Waterfield, CJ; et al. "Effect of treatment with ß-agonists on tissue and urinary taurine levels in rats: Mechanism and implications for protection". In Advances in experimental medicine and biology, 233-245. 1996.
    Published • 10.1007/978-1-4899-0182-8_25
  53. Gonçalves, J.; Carvalho, F.; Guimarães, S.; GONCALVES, J; CARVALHO, F; GUIMARAES, S; LANGER, SZ; GALZIN, AM; COSTENTIN, J. "Does the Distance Between Nerve Varicosities and Adrenoceptors Play Any Role in the Relative Contribution of ATP/Noradrenaline for Postjunctional Response?". In Presynaptic Receptors and Neuronal Transporters, 29-30. Elsevier, 1991.
    10.1016/b978-0-08-041165-1.50013-2
Book review
  1. Aschner, M.; Domingo, J.L.; Carvalho, F.; Abdollahi, M.; Wallace, H.. "Endorsements". (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85128100273&partnerID=MN8TOARS.
    Published
Conference abstract
  1. Roque-Bravo, Rita; Carmo, Helena; Silva, João Pedro; Carvalho, Félix; Dias da Silva, Diana. "P21-11: Synthetic Cannabinoids and senescence markersi n vitro: impact on cell proliferation, influence of cannabinoid receptors, and beta-galactosidase activity in SH-SY5Y cells". Paper presented in 57th Congress of the European Societies of Toxicology (EUROTOX), Ljubljana, 2023.
    Published
  2. Adelaide Sousa; Ana T. Rufino; Ana Ramalho; Carvalho, Félix; Eduarda Fernandes; Freitas, Marisa; Ana Rufino; Marisa Freitas. "Silver nanoparticles induce an inflammatory response of intestinal C2BBe1 cells". Paper presented in SOT 62nd Annual Meeting and ToxExpo (Toxicological Sciences), 2023.
    Published
  3. Roque Bravo, Rita; Barbosa, D.J.; Carmo, Helena; Silva, João Pedro; Carvalho, Félix; Dias da Silva, Diana. "The influence of selected synthetic cannabinoids on in vitro proliferation and viability of neuronal cell models". Paper presented in XVI International Congress of Toxicology, Maastricht, 2022.
    Published
  4. Maria B. André; Silvestre, Ricardo; Azevedo, Rui M.S.; Carvalho, Félix; Dinis-Oliveira, Ricardo Jorge. "Profiling of rat mRNA transcripts degradation for the postmortem interval estimation". Paper presented in I Congresso Internacional da TOXRUN / V Congresso Internacional da Associação Portuguesa de Ciências Forenses / XIV Jornadas Científicas do Departamento de Ciências do Instituto Universitário de Ciências da Saúde, Porto, 2022.
    Published • https://doi.org/10.51126/revsalus.v4iSup.249
  5. Lobato-Freitas, Carolina; Carmo, Helena; Carvalho, Félix; Silva, João Pedro; da Silva, Diana Dias. "AMB-FUBINACA, AB-CHMINACA and HU-308¿s effects on in vitro differentiation and proliferation of NG108-15 cells". Paper presented in I International Congress of TOXRUN ¿ Toxicology Research Unit of IUCS¿ and ¿V International Congress of the Portuguese Association of Forensic Sciences, 2022.
  6. Garcia, M.R.; Roque Bravo, Rita; Carmo, Helena; Carvalho, Félix; Silva, João Pedro; Dias da Silva, Diana. "Mitochondrial effects and Caspase-3 activation induced by synthetic cannabinoids in NG108-15 cells.". Paper presented in Annual Congress of APCF-TOXRUN, Porto, 2022.
    Published • https://doi.org/10.51126/revsalus.v4iSup.264
  7. Pereira Teixeira, Catarina; Garcia, MR; Roque Bravo, Rita; Carmo, Helena; Carvalho, Félix; Silva, João Pedro; Dias da Silva, Diana. "Synthetic cannabinoids affect the expression of autophagic mediators ATG5, BECLIN-1, RAB7A and LC3 in brain-derived NG108-15 cells". Paper presented in Annual Congress of APCF-TOXRUN, Porto, 2022.
    Published • https://doi.org/10.51126/revsalus.v4iSup.371
  8. Henriques, Rita; Bravo, Rita R.; Carmo, Helena; Silva, João Pedro; Carvalho, Félix. "In vitro evaluation of telomere length in SH-SY5Y neuroblastoma cells exposed to heroin and tramadol". Paper presented in Young Researchers Meating IJUP, Porto, 2022.
    Published
  9. Adelaide Sousa; Azevedo, Rui; Sara Oliveira; Inês Preguiça; Sofia Viana; Flávio Reis; Agostinho Almeida; et al. Corresponding author: Freitas, Marisa. "Biodistribution and cytokine production following oral administration of silver nanoparticles to C57BL/6J mice.". Paper presented in XVIth International Congress of Toxicology (Toxicology Letters), 2022.
    Published
  10. Marques, Sandra; Silva, João Pedro; Carmo, Helena; Carvalho, Félix. "Varenicline increases histone H3 acetylation, while affecting global DNA methylation on differentiated SH-SY5Y neuroblastoma cells. Published in Toxicology Letters (SENIOR AUTHOR)". Paper presented in EUROTOX2021, 2021.
    Published
  11. Carmo, Helena; Rouxinol, Daniela; Silva, João Pedro; Bastos, Maria de Lourdes; Carvalho, Félix; Dias da Silva, Diana. "Release of Antidiuretic Hormone (ADH) in Wistar Rats in Response to the Administration of Methylone and 3,4-DMMC: The Gender Impact". Paper presented in 51st Meeting of the Portuguese Society of Pharmacology, 39th Meeting of Clinical Pharmacology and 20th Meeting of Toxicology, Lisboa, 2021.
    Published
  12. Malheiro, Rui; Carmo, Helena; Carvalho, Félix; Silva, João Pedro. "In vitro evaluation of the effects of the synthetic cannabinoids ADB-FUBINACA and AMB-FUBINACA on mitochondrial function during neurodifferentiation. Published in Toxicology Letters (SENIOR AUTHOR)". Paper presented in EUROTOX2021, 2021.
    Published
  13. Barbosa, Joana; Faria, Juliana; Leal, S; Nascimento, Ana Vanessa; Afonso, Luís Pedro; Moreira, Roxana; Pereira, Frederico; et al. "O Tramadol e o Tapentadol causam Hepato e Necrotoxicidade em Ratos Wistar expostos subcronicamente a doses terapêuticas". Paper presented in 3.ª Reunião da Rede Académica nas Ciências da Saúde da Lusofonia, 2020.
    Published
  14. Roque Bravo, Rita; Carmo, Helena; Silva, João Pedro; Carvalho, Félix; Bastos, ML; Dias da Silva, Diana. "Metabolism plays an important role in the in vitro hepatotoxicity of butylone, buphedrone, and 3,4-dimethylmetcathinone (3,4-DMMC). Published in Toxicology Letters". Paper presented in EUROTOX2019, Helsinki, 2019.
    Accepted
  15. Alexandre, JA; Malheiro, RM; Dias da Silva, Diana; Carmo, Helena; Carvalho, Félix; Silva, João Pedro. "Synthetic cannabinoids 5F-PB22 and THJ-2201 promote in vitro CB1 receptor-dependent neuronal differentiation at in vivo-relevant concentrations. Published in Toxicology Letters (SENIOR AUTHOR)". Paper presented in EUROTOX2019, Helsinki, 2019.
    Accepted
  16. Faria, AC; Carmo, Helena; Teixeira, Catarina; Rouxinol, D; Silva, João Pedro; Carvalho, Félix; Bastos, ML; Dias da Silva, Diana. "Administration of 3,4-dimethylmethcathinone (3,4-DMMC) and methylone increases the release of antidiuretic hormone in female Wistar rats. Published in Toxicology Letters". Paper presented in EUROTOX2019 ¿ 55th Congress of the European Societies of Toxicology, Helsinki, 2019.
    Accepted
  17. Teixeira, C; Carmo, Helena; Rouxinol, D; Faria, AC; Silva, João Pedro; Carvalho, Félix; Bastos, ML; Dias da Silva, Diana. "Administration of 3,4-dimethylmethcathinone (3,4-DMMC) and methylone to Wistar rats disturbs the energetic and antioxidant homeostasis in liver, brain, kidney and heart. Published in Toxicology Letters". Paper presented in EUROTOX2019 ¿ 55th Congress of the European Societies of Toxicology, Helsinki, 2019.
  18. Rouxinol, D; Dias da Silva, Diana; Teixeira, C; Faria, AC; Silva, João Pedro; Carvalho, Félix; Bastos, ML; Carmo, Helena. "Biodistribution of the new psychoactive stimulant 3,4-dimethylmethcathinone (3,4-DMMC) in Wistar rats assessed by gas chromatography-mass spectrometry (GC-MS). Published in Toxicology Letters". Paper presented in Eurotox2019, Helsinki, 2019.
  19. Dias-Carvalho, Ana; Reis-Mendes, A.; Duarte-Araújo, Margarida; Guedes, Rita; Gonçalves-Monteiro, Salomé; Carvalho, Félix; Bastos ML; Capela JP; Costa VM. "In vivo chemobrain study: the effects of doxorubicin and mitoxantrone in the brain of differently aged mice". Paper presented in Porto Biomed. J., 2019.
    Published
  20. Dias-Carvalho, Ana; Reis-Mendes, A.; Duarte-Araújo, Margarida; Carvalho, Félix; Bastos ML; Sá, SI; Capela JP; Costa VM. "Chemobrain study: differential effects of doxorubicin and mitoxantrone in the brain of CD-1 mice". Paper presented in 1st International Electronic Conference on Brain Sciences., 2019.
  21. Alexandre, João; Malheiro, Rui; Dias da Silva, Diana; Carmo, Helena; Carvalho, Félix; Silva, João Pedro. "Synthetic cannabinoids 5F-PB22 and THJ-2201 promote in vitro CB1 receptor-dependent neuronal differentiation at in vivo-relevant concentrations". Paper presented in The 55th Congress of the European Societies of Toxicology (EUROTOX 2019), Helsinki, 2019.
    Published
  22. Nicola, Pedro (presenter); Freitas, Marisa; Rocha, Sónia; Carvalho, Félix; Fernandes, Eduarda; Ribeiro, Daniela. "Optimization of a synaptosomal model to study the effect of carotenoids in peroxynitrite - induced lipid peroxidation". Paper presented in YES (Young European Scientist) Meeting [Porto Biomed. J., 3 (3) (2018) PS106. ISSN: 2444-8672], Oporto, 2018.
    Published
  23. Parra, J; Araújo, ARTS; Carmo, Helena; Carvalho, Félix; Silva, João Pedro. "Neurotoxicity assessment of four synthetic cathinones in neuroblastoma cells at in vivo relevant concentrations. Published in Toxicology Letters (SENIOR AUTHOR)". Paper presented in EUROTOX 2018, 2018.
  24. Barbosa, Joana; Faria, Juliana; Leal, Sandra; Afonso, L. P.; Queiros, Odilia; Moreira, Roxana; Carvalho, Félix; Dinis-Oliveira, Ricardo Jorge. "Acute administration of tramadol and tapentadol induces dose-dependent toxicity in Wistar rats, affecting both metabolizing and target organs". Paper presented in XLVII Reunião da Sociedade Portuguesa de Farmacologia, Coimbra, 2017.
    Published
  25. Silva, João Pedro; Carmo, Helena; Carvalho, Félix. "In vitro nephrotoxicity of synthetic cannabinoids. Published in Toxicology Letters". Paper presented in EUROTOX 2017, 2017.
  26. Barbosa, Daniel José; Serrat, Romàn; Mirra, Serena; Quevedo, Martí; Barreda, Elena Gomes; Àvila, Jesus; Fernandes, Eduarda; et al. ""Ecstasy" impairs mitochondrial trafficking in hippocampal neurons by a Tau phosphorylation-dependent mechanism involving GSK3ß". Paper presented in 49th Congress of the European Societies of Toxicology (EUROTOX), Interlaken, 2013.
    Published
  27. Diana Couto; Freitas, Marisa; M. Arturo Lopez-Quintela; José Rivas; Paulo Freitas; Carvalho, Félix; Eduarda Fernandes. "Iron oxide nanoparticles accelerate apoptotic death of human neutrophils". Paper presented in International Conference and Exhibition on Nanotechnology & Nanomedicine (Journal of Nanomedicine Nanotechnology), 2012.
    Published
  28. Sousa, Teresa; Fernandes, Eduarda; Carvalho, Félix; Laranjinha, João; Nunes, Carla; Albino-Teixeira, António; Sousa, T; et al. "Inactivaction of nitric oxide by a xanthinic hypertensive agent". 2002.
    Published • 10.1109/eit.2009.5189608
Conference paper
  1. Brandão, Sofia; Filipa Reis-Mendes, Ana; Neuparth, Maria João; Carvalho, Félix; Ferreira, Rita; Costa, Vera M. "Cardiac mitochondrial dynamics, autophagy and regeneration are stirred by doxorubicin in old CD-1 mice". Paper presented in II TOX-RUN 2023, Porto, 2023.
    Published
  2. Vitorino-Oliveira, Claúdia; Kahremany, S; Nisim, L; Duarte-Araújo, M.; Carvalho, Félix; Gruzman, Arie; Costa, Vera M. "The influence of glutathione pathway modulators on the cytotoxicity of sunitinib, doxorubicin and bortezomib in AC16 cardiac cells". Paper presented in II TOX-RUN 2023, Porto, 2023.
    Published
  3. Sílvia Rocha; Álvaro Tomé; Ana Teresa Rufino; Marisa Freitas; Félix Carvalho; Artur Silva; Eduarda Fernandes. "Chalcones as Potential Inhibitors of Pancreatic Lipase". 2022.
    10.3390/ECMC2022-13413
  4. Adelaide Sousa; Ana Ramalho; Félix Carvalho; Eduarda Fernandes; Marisa Freitas. "Polyvinylpyrrolidone-Coated Silver Nanoparticles Induce the Expression of Inducible Nitric Oxide Synthase in Intestinal C2BBe1 Cells". 2022.
    10.3390/ECMC2022-13196
  5. Carvalho, Ana; Ferreira, Mariana; Filipa Reis-Mendes, Ana; Ferreira, Rita; Bastos, Maria De Lourdes; Fernandes, Eduarda; Sá, Susana I; Sá SI; et al. "Unveiling the neurotoxicity of mitoxantrone: oxidative stress, apoptosis, and autophagy in the brain of adult CD-1 mice". Paper presented in 8th International Electronic Conference on Medicinal Chemistry, 2022.
    Published
  6. Ferreira, Mariana; Carvalho, Félix; Costa, Vera M; Capela, João Paulo. "Evaluating the potential of methylphenidate and amphetamine acute exposure to promote neurite outgrowth and synaptogenesis in differentiated SH-SY5Y neuronal cells". Paper presented in 8th International Electronic Conference on Medicinal Chemistry, Online, 2022.
    Published
  7. Brandão, Sofia; Reis-Mendes, A.; Duarte-Araujo, M.; Neuparth, Maria João; Carvalho, Félix; Ferreira, Rita; Costa, Vera M. "Mitoxantrone disrupts cardiac metabolism along with proteolysis and regeneration in aged mice". Paper presented in 8th International Electronic Conference on Medicinal Chemistry, Online, 2022.
    Published
  8. Carvalho, Ana; Ferreira, Mariana; Reis-Mendes, Ana; Ferreira, Rita; Fernandes, Eduarda; Sá, Susana I; Capela, João Paulo; Carvalho, Félix; Costa, Vera M. "Mitoxantrone-induced neurotoxicity in CD-1 mice.". Paper presented in I TOXRUN, Porto, 2022.
    Published
  9. Brandão, Sofia Reis; Filipa Reis-Mendes, Ana; Duarte-Araujo, M.; Neuparth, Maria João; Carvalho, Félix; Ferreira, Rita; Costa, Vera M. "Molecular alterations underlying Doxorubicin¿s Chronic Cardiotoxicity in a mouse model". Paper presented in I TOXRUN, Porto, 2022.
    Published
  10. Fernando Remiao; Renata Silva; Vera Costa; Helena Carmo; Felix Carvalho. "Pharmacy education by using open educational resources produced in collaborative Erasmus+ projetcts". 2022.
  11. Araújo, Ana Margarida; Carvalho, Márcia; Fernandes, Eduarda; Bastos, Maria de Lourdes; Carvalho, Félix; Guedes de Pinho, Paula. "Toxicometabolomic insights into the mechanisms of hepatotoxicity triggered by amphetaminic drugs". 2021.
  12. Araújo, Ana Margarida; Carvalho, Márcia; Costa, Vera; Duarte, José Alberto; Dinis-Oliveira, Ricardo; Bastos, Maria de Lourdes; Guedes de Pinho, Paula; Carvalho, Félix. "A translational in vitro and in vivo metabolomics study reveals altered hepatic metabolic pathways after acute exposure to 3,4-methylenedioxypyrovalerone". 2021.
  13. Araújo, Ana Margarida; Carvalho, Márcia; Costa, Vera Marisa; Duarte, José Alberto; Dinis-Oliveira, Ricardo; Bastos, Maria de Lourdes; Guedes de Pinho, Paula; et al. "Early pathways of toxicity triggered by 3,4-methylenedioxypyrovalerone unveiled by in vivo toxicometabolomics". Paper presented in EUROTOX, 2021.
    10.1016/S0378-4274(21)00553-1
  14. Carvalho, Ana Rita; Reis-Mendes, A.; Duarte-Araujo, Margarida; Carvalho, Félix; Bastos, Maria de Lourdes; Sá, Susana I; Capela, João Paulo; Costa, Vera M. "Mitoxantrone impairs Bax and phosphorylated Tau expression on the brain of adult mice: an in vivo ¿chemobrain¿ study on clinically relevant doses.". Paper presented in 15th YES Meeting Porto 2020, Porto, 2020.
    Published • 10.1097/j.pbj.0000000000000100
  15. Malheiro, Rui Filipe; Costa, Vera Marisa; Bastos, Maria de Lourdes; Carvalho, Félix. "In vitro toxicity of alpha-amanitin in human kidney cells and evaluation of protective effect of polymyxin B". Paper presented in 5th International Electronic Conference on Medicinal Chemistry, 2019.
    10.3390/ecmc2019-06360
  16. Dionísio, Flávio; Araújo, Ana Margarida; Araújo, Margarida Duarte; de Pinho, Paula Guedes; Bastos, Maria de Lourdes; Carvalho, Félix; Costa, Vera Marisa. "The main products of cyclophosphamide bioactivation exert a cardiotoxic effect at clinical important concentrations in AC16 cardiac cells". Paper presented in 5th International Electronic Conference on Medicinal Chemistry, 2019.
    10.3390/ecmc2019-06366
  17. Dionísio, Flávio; Duarte-Araújo, Margarida; Bastos, Maria de Lourdes; Carvalho, Félix; Costa, Vera M. "Cyclophosphamide metabolites 4-hydroxycyclophosphamide and acrolein exert strenuous cardiotoxicity in AC16 human cardiomyocytes, at clinical relevant concentrations". Paper presented in EUROTOX 2019 - 55th Annual Meeting of the Society of the European Toxicology Society, 2019.
    Published
  18. Faria, Juliana; Barbosa, Joana; Leal, S; Nascimento, Ana Vanessa; Afonso, L. P.; Pereira, F.; Carvalho, Félix; Dinis-Oliveira, Ricardo Jorge. "Sub-chronic administration of tramadol and tapentadol therapeutic doses induces reurotoxicity in Wistar rats". Paper presented in XI Jornadas Científicas de Ciências do IUCS/IV Congresso Associação Portuguesa de Ciências Forenses, Porto, 2019.
    Published
  19. Barbosa, Joana; Faria, Juliana; Leal, S; Nascimento, Ana Vanessa; Afonso, L. P.; Queiros, Odilia; Pereira, F.; et al. "Sub-chronic exposure to therapeutic doses of tramadol and tapentadol causes hepatoxicity in Wistar rats". Paper presented in XI Jornadas Científicas de Ciências do IUCS/IV Congresso Associação Portuguesa de Ciências Forenses, Porto, 2019.
    Published
  20. Remião, Fernando; Carmo, Helena; Gomes, AM; Silva, Renata; Costa, Vera M; Carvalho, Félix; Bastos, Maria De Lourdes. "Video lecture capture (VLC) - impacto na aprendizagem dos estudantes". Paper presented in Congr. Nac. Práticas Pedagógicas no Ensino Superior, 2019.
    Published
  21. Reis-Mendes, Ana; Duarte-Araújo, Margarida; Duarte, José Alberto; Gonçalves-Monteiro, Salomé; Remião, Fernando; Carvalho, Félix; Sousa, Emília; Bastos, Maria Lourdes; Costa, Vera Marisa. "Anticancer drugs-induced toxicity in different age male CD-1 mice". 2019.
    10.3390/ecmc2019-06365
  22. Dias-Carvalho, Ana; Reis-Mendes, Ana; Duarte-Araújo, Margarida; Carvalho, Félix; Bastos, Maria Lourdes; Sá, Susana I.; Capela, João Paulo; Costa, Vera Marisa. "Effects of Doxorubicin and Mitoxantrone in the brain of differently aged mice: in vivo chemobrain study". 2019.
    10.3390/ecmc2019-06364
  23. Araújo, Ana Margarida; Enea, Maria; Fernandes, Eduarda; Bastos, Maria de Lourdes; Carvalho, Félix; Guedes de Pinho, Paula; Carvalho, Márcia. "A new strategy for exploring the role of hyperthermia in MDMA-induced toxicity in primary mouse hepatic cells using GC-MS-based metabolomics". 2019.
    10.1016/j.toxlet.2019.09.002
  24. Araújo, Ana Margarida; Bastos, Maria de Lourdes; Fernandes, Eduarda; Carvalho, Félix; Carvalho, Márcia; Guedes de Pinho, Paula. "Metabolomics approach in the investigation of hepatic metabolic changes caused by MDMA". 2019.
  25. Carvalho, Ana Rita; Ana Reis-Mendes; Duarte-Araujo, Margarida; Guedes, Rita; Gonçalves-Monteiro, Salomé; Carvalho, Félix; Bastos, Maria De Lourdes; Capela, João Paulo; Costa, Vera M. "Differential effects of doxorubicin and mitoxantrone in brain glutathione levels of different aged mice". Porto, 2018.
    Published
  26. Araújo, Ana Margarida; Bastos, Maria de Lourdes; Carvalho, Félix; Carvalho, Márcia; Guedes de Pinho, Paula; de Lourdes Bastos, Maria; de Pinho, Paula Guedes. "Metabolomic analysis reveals metabolic disturbances in primary mouse hepatocytes induced by subtoxic concentrations of methylone". Paper presented in XLVIII Reunião da Sociedade Portuguesa de Farmacologia, XXXVI Reunião de Farmacologia Clínica, e XVII Reunião de Toxicologia, Lisboa, 2018.
  27. Georgina Correia da Silva; Marta Almada; Bruno Fonseca; Miguel Morais; Felix Carvalho; Teixeira, NA. "The impact of phyto and synthetic cannabinoids in placental cytotrophoblast cells turnover". 2016.
  28. Costa, Vera M; Capela, João Paulo; Bastos, Maria De Lourdes; Duarte, Jose Alberto; Remião, Fernando; Carvalho, Félix. "Pharmacological concentrations of mitoxantrone are able to activate caspases and dually modify glutathione pathways in HL-1 cardiomyocytes.". Paper presented in 6th European Congress on Pharmacology EPHAR 2012, Granada, 2012.
    Published
  29. Duarte, Tiago; Bento, A; Picarote, G; Costa, Vera M; Carvalho, Félix. "Understanding the role of NRF2/ARE signalling in the cellular defence against iron toxicity". Paper presented in International BioIron Society Biennial World Meeting (IBIS 2011 - Vancouver), Vancouver, 2011.
    Published
  30. Rossato, Luciana Grazziotin; Costa, Vera M; de Pinho, Paula Guedes; Carvalho, Félix; Carmo, Helena; Bastos, Maria De Lourdes; Remião, Fernando. "Role of organic cation mediated transport and oxidative stress in the synephrine induced-toxicity in freshly isolated cardiomyocytes. Toxicol Lett 196S: S142.". Paper presented in 2010 IUTOX International Congress of Toxicology, Barcelona, 2010.
    Published
  31. Rossato, Luciana Grazziotin; Costa, Vera M; de Pinho, Paula Guedes; Silva, Renata; Carvalho, Félix; Carmo, Helena; Bastos, Maria de Lourdes; Remião, Fernando. "Development of a GC/IT-MS method for simultaneous quantification of para and meta-synephrine in Caco-2 cells". Paper presented in 2010 IUTOX International Congress of Toxicology, Barcelona, 2010.
    Published
  32. Gomes, Ana Sara; Vieira, D.; Sousa, Maria; Afonso, Carlos; Pinto, Madalena; Carvalho, Félix; Santos-Silva, A.; et al. "TXA1, a small molecule potent inhibitor of human tumor cell growth: synthesis and toxicological characterization". Paper presented in 2nd National Meeting on Medicinal Chemistry, 2010.
  33. Oliveira, Susana; Almeida, SF ; Picarote, Gonçalo; Costa, Vera M; Carvalho, Félix; Azevedo, JE; Pinto, Jorge P; Sousa, Maria. "Activation of an unfolded protein response modulates the expression of iron-related genes". Paper presented in 2009 International BioIron Society Meeting, Porto, 2009.
    Published
  34. Costa, Vera M; Carvalho, Márcia; Carvalho, Félix; Bastos, Maria De Lourdes; Carvalho, Rui; Remião, Fernando. "Effect of catecholamine and free radicals on calcium tolerant cardiomyocytes: adduct formation". Paper presented in 43rd Congress of the European Societies of Toxicology and the 6th Congress of Toxicology in Developing Countries, Cavtat, Croatia, Cavtat, 2006.
    Published
  35. Sousa, Teresa; Manuela Morato; Pinho, Dora; Fernandes, E; Carvalho, Félix; Albino-Teixeira, António. Corresponding author: Albino-Teixeira, António. "Increased oxidative stress in the mesenteric artery from hypertensive rats with activation of the renin-angiotensin system. In: Martins e Silva J, Saldanha C, Oliveira V, Prie A, Shore A (eds). Proceedings of the 23rd Conference of Microcirculation, Medimond Publishing CO, pp 137-140. ISBN: 88-7587-078-0". Paper presented in 23rd European Conference on Microcirculation, 2004.
    Published
  36. Carvalho, Márcia; Milhazes, Nuno; Remião, Fernando; Borges, Fernanda; Fernandes, Eduarda; Monks, Terrence J.; Carvalho, Félix; Bastos, Maria Lourdes. "Hepatotoxic effects of 3,4-methylenedioxyamphetamine and a-methyldopamine in freshly isolated rat hepatocytes". Paper presented in Toxicology Letters, 2003.
  37. Carvalho, Márcia; Milhazes, Nuno; Remião, Fernando; Borges, Fernanda; Fernandes, Eduarda; Carvalho, Félix; Bastos, Maria Lourdes. "The metabolism of 3,4-methylenedioxymethamphetamine (ecstasy) into N-methyl-a-methyldopamine drastically increases its in vitro toxicity". Paper presented in Toxicology Letters, Florence, 2003.
  38. Fernandes, Eduarda; Carvalho, Márcia; Carvalho, Félix; Silva, Artur; Santos, Clementina M.M.; Pinto, Diana; Cavaleiro, José; Bastos, Maria de Lourdes. "Hepatoprotective activity of 2-styrylchromone derivatives against the pro-oxidant hepatotoxic effect elicited by tert-butylhydroperoxide in freshy isolated rat hepatocytes". 2003.
  39. Amado, F.M.; Remião, F.; Milhazes, N.; Borges, F.; Carvalho, F.D.; Bastos, M.L.; Domingues, P.M.; Ferrer-Correia, A.J.. "Analysis of aminochromes by ESI-MS/MS determination of adrenochrome in rat blood". 2002.
  40. Sousa, Teresa; Fernandes, E; Morato, Manuela; Carvalho, Félix; Albino-Teixeira, António. Corresponding author: Albino-Teixeira, António. "Antioxidant enzyme activity in mesenteric artery fromDPSPX (1,3-dipropyl-8-sulfophenylxanthine)-hypertensive rats. In: Tooke J, Shore A, Whatmore J (Eds). The Microcirculation and Vascular Biology - Proceedings of the 22nd Meeting of the European Society for Microcirculation. Medimond SRL, pp 267-270. ISBN: 88-323-2828-3". Paper presented in 22nd Meeting of the European Society for Microcirculation, 2002.
    Published
  41. Lima, Cristóvão F.; Carvalho, Felix; Fernandes, Eduarda; Bastos, Maria de Lurdes; Gomes, P. Santos; Ferreira, Manuel Fernandes; Wilson, Cristina Pereira. "Evaluation of toxic and protective effects of an essential oil of Salvia officinalis L. on liver cells". 2002.
  42. Fernandes, Eduarda; Carvalho, Félix; Silva, Artur; Santos, Clementina M.M.; Pinto, Diana; Cavaleiro, José; Bastos, Maria de Lourdes. "Potent Inhibition of Xanthine Oxidase by Novel 2-Styrylchromones". 2001.
Conference poster
  1. Ana Ramalho; Carvalho, Félix; Eduarda Fernandes; Freitas, Marisa. "Unveiling the neutrophil response to parabens". Paper presented in XVII Encontro Luso-Galego de Química, 2023.
  2. Inês Santos; Adelaide Sousa; Carvalho, Félix; Eduarda Fernandes; Freitas, Marisa. "In vitro effects of silver nanoparticles and potential protective role of quercetin on the intestinal cell line C2BBe1". Paper presented in XVII Encontro Luso-Galego de Química, 2023.
  3. Dias-Carvalho, Ana; Araújo, Ana Margarida; Reis-Mendes, A.; Sequeira, CO; Pereira, AS; Guedes de Pinho, Paula; Carvalho, Félix; et al. "Chemobrain: exploring the impacto f a clinically relevant dose of mitoxantrone in the metabolic profile of CD-1 mice brain". Paper presented in EMBO Young Scientists¿ Forum (Lisbon), 2023.
  4. Galipeau, Chloé; Miguel Farinha-Ferreira; Marques, Sandra; Silva, João Pedro; Mariani, JC; Diebolt, S; Barthe, L; et al. "The role of 5-HT2AR activation in the long-lasting effects of psilocybin". Paper presented in European Molecular Biology Organization (EMBO) Young Scientist Forum, 2023.
  5. Roque Bravo, Rita; Carmo, Helena; Silva, João Pedro; Carvalho, Félix; Dias da Silva, Diana. "Synthetic Cannabinoids and senescence markersi n vitro: impact on cell proliferation, influence of cannabinoid receptors, and beta-galactosidase activity in SH-SY5Y cells". Paper presented in 57th Congress of the European Societies of Toxicology (EUROTOX), 2023.
  6. Malheiro, RF; Carmo, Helena; Carvalho, Félix; Silva, João Pedro. Corresponding author: Silva, João Pedro. "THJ-2201, a synthetic cannabinoid, modulates mitochondrial function and dynamics during the neurodifferentiation of NG108-15 cells at biologically relevant concentrations". Paper presented in EUROTOX 2023, 2023.
  7. Silva, Rafaela; Barbosa, Daniel José; Carmo, Helena; Carvalho, Félix; da Silva, D. Dias; Silva, João Pedro. Corresponding author: Silva, João Pedro. "The impact of ADB-FUBINACA on the differentiation, maturation and astrocyte activation in in vitro primary hippocampal cultures.". Paper presented in EUROTOX 2023, 2023.
  8. Pereira-Teixeira, C.; Almeida, Mariana; Carmo, Helena; Carvalho, Félix; Silva, João Pedro. Corresponding author: Silva, João Pedro. "The synthetic cannabinoid ADB-FUBINACA decreases global DNA methylation during the neuronal differentiation of NG108-15 cells by increasing TET activity". Paper presented in EUROTOX 2023, 2023.
  9. Adelaide Sousa; Rui Azevedo; Costa, Vera M; Sara Oliveira; Inês Preguiça; Sofia Viana; Flávio Reis; et al. "Impact of dietary exposure to silver nanoparticles on the intestinal inflammatory response in C57BL/6J mice". Paper presented in 12th International Symposium on Biological Monitoring in Occupational and Environmental Health, 2023.
  10. Dias-da-Silva, Diana; Roque Bravo, Rita; Silva, João Pedro; Carmo, Helena; Carvalho, Félix. Corresponding author: Dias-da-Silva, Diana. "The synthetic cannabinoids ADB-FUBINACA and AMB-FUBINACA accelerate SH-SY5Y proliferation via stimulation of CB1 and CB2 cannabinoid receptors". Paper presented in II TOXRUN International Congress, 2023.
  11. Valente, Maria João; Araújo, Ana Margarida; Carvalho, Félix; Carvalho, Márcia. "Toxicity of amphetamine-type drugs in rat cardiomyocyte cells involves oxidative stress and the formation of acidic vesicular organelles". Paper presented in II TOXRUN International Congress 2023 - No Boundaries for Toxicology: One Health, One Society, One Planet, 2023.
  12. Sandra Marques; Catarina Pereira-Teixeira ; Helena Carmo; Carvalho, Félix; João Pedro Silva; Marques, Sandra; Carmo, Helena; Silva, João Pedro. "Pharmaceuticals associated with mood and cognitive adverse events promote epigenetic changes in human-induced pluripotent stem cells-derived glutamatergic neurons at clinically-relevant concentrations". Paper presented in Society of Toxicology - 62nd Annual Meeting & TOXEXPO, 2023.
  13. Maria Carolina Lobo; Proença, Carina; Rocha, Silvia; Rufino, Ana T.; Carvalho, Félix; Silva, Artur M. S.; Eduarda Fernandes. "Flavonoids as potential anti-obesogenic agents through modulation of pancreatic lipase and protein tyrosine phosphatase 1B: a structure-activity relationship". 2023.
  14. Araújo, Ana Margarida; Marques, Sandra; Pinho, Paula Guedes; Carmo, Helena; Carvalho, Félix; Silva, João Pedro. "Application of a GC-MS metabolomics approach to reveal how sub-toxic concentrations of ciprofloxacin affect the brain". Paper presented in 12th National Meeting on Chromatography, 2022.
  15. Lobato-Freitas, Carolina; Carmo, Helena; Carvalho, Félix; Silva, João Pedro; da Silva, Diana Dias. "The effects of Synthetic Cannabinoids ADB-FUBINACA, AMB-FUBINACA, AB-CHMINACA and HU-308 on Differentiation and Proliferation of Brain NG108-15 Cells". Paper presented in Lisbon Addictions 2022, 2022.
  16. da Silva, Diana Dias; Teixeira, Catarina; Garcia, Maria Rita; Roque-Bravo, Rita; Carmo, Helena; Carvalho, Félix; Silva, João Pedro. "Crosstalk Between Autophagic Intermediaries in In Vitro Neurotoxicity Induced by Synthetic Cannabinoids". Paper presented in Lisbon Addictions 2022, 2022.
  17. Telma M. Gomes; RF Malheiro; Mariana Almeida; Helena Carmo; Silva, João Pedro; Carvalho, Félix. "The synthetic cannabinoid ADB-FUBINACA modulates epigenetic mechanisms during in vitro neuronal differentiation at biologically relevant concentrations". Paper presented in Lisbon Addictions 2022, 2022.
  18. Marques, Sandra; Carmo, Helena; Carvalho, Félix; Sá, Susana I; Sá SI; Silva, João Pedro. "An improved IHC image post-processing method for the semi-automatic quantification of astrocyte number and activation". Paper presented in 8th International Electronic Conference on Medicinal Chemistry, 2022.
  19. Brandão, Sofia Reis; Filipa Reis-Mendes, Ana; Duarte-Araújo, M.; Rocha, Hugo; Neuparth, Maria João; Carvalho, Félix; Ferreira, Rita; Costa, Vera M. "Cardiac metabolic adaptation after doxorubicin and mitoxantrone on adult mice". Paper presented in 1st Conference of the Doctoral Program Metabolism ¿ Clinical and Experimental, The prism of Diabesity: looking by a different perspective, 2022.
  20. Teixeira, Catarina; Garcia, Maria Rita; Roque-Bravo, Rita; Carmo, Helena; Carvalho, Félix; Silva, João Pedro; da Silva, Diana Dias. "Autophagic proteins ATG5, Beclin-1, Rab7A and LC3 are altered by Synthetic Cannabinoids in NG108-15 brain-derived cells". Paper presented in 15th IJUP (Meeting of University of Porto¿s Young Researchers), 2022.
  21. Lobato-Freitas, Carolina; Carmo, Helena; Carvalho, Félix; Silva, João Pedro; da Silva, Diana Dias. "Synthetic Cannabinoids in Differentiation and Proliferation of NG108-15 Cells in vitro". Paper presented in 15th IJUP (Meeting of University of Porto¿s Young Researchers), 2022.
  22. Maria Carolina Lobo; Sílvia Rocha; Freitas, Marisa; Carvalho, Félix; Artur M.S. Silva; Eduarda Fernandes; Ana T. Rufino. "In vitro inhibitory activity of polyphenols against pancreatic lipase and a-amylase". Paper presented in IJUP¿15th Meeting of Young Researchers of University of Porto, 2022.
  23. Maria Carolina Lobo; Rocha, S.; Carvalho, Félix; Silva, Artur; Fernandes, Eduarda; Rufino A.. "In vitro activity of polyphenols against pancreatic lipase and a-amylase inhibition". Paper presented in IJUP - Young Researchers Meeting, 2022.
  24. Maria Carolina Lobo; Rocha, S.; Rufino A.; Carvalho, Félix; Silva, Artur; Fernandes, Eduarda. "Inhibition of Pancreatic Lipase and a-Amylase by Polyphenols in In Vitro Microanalysis Systems". Paper presented in 14th Edition of the Nacional Organic Chemistry Meeting and 7th Edition of the Nacional Therapeutic Chemistry Meeting, 2022.
  25. Ana T. Rufino; Ana Ramalho; Adelaide Sousa; José Miguel P. Ferreira de Oliveira; Paulo Freitas; Manuel A. Gonzalez Gómez; Yolanda Piñeiro-Redondo; et al. Corresponding author: Freitas, Marisa. "Evaluation of cytotoxic and pro-inflammatory effects of silver nanoparticles: Potential protective effect of flavonoids". Paper presented in 14th National Organic Chemistry Meeting & 7th National Medicinal Chemistry Meeting., 2022.
  26. Roque Bravo, Rita; Barbosa, Daniel José; Carmo, Helena; Silva, João Pedro; Carvalho, Félix; Dias da Silva, Diana. "SYNTHETIC CANNABINOIDS AMB-FUBINACA, ADB-FUBINACA, AB-CHMINACA AND THJ-2201 IMPACT ON IN VITRO VIABILITY AND PROLIFERATION OF PRIMARY RAT HIPPOCAMPAL NEURONS AND SH-SY5Y CELLS". Paper presented in I Congresso Internacional da TOXRUN; V Congresso Internacional da Associação Portuguesa de Ciências Forenses, 2022.
  27. Araújo, Ana Margarida; Carmo, Helena; Carvalho, Félix; Silva, João Pedro; Sandra Marques; Carmo, Helena; Maria Paula do Amaral Alegria Guedes de Pinho; João Pedro Silva. "Can fluoroquinolones affect the brain? - A GC-MS metabolomics approach reveals early neurotoxicity events triggered by ciprofloxacin". Paper presented in 61st Society of Toxicology (SOT) Annual Meeting, 2022.
  28. Ferreira, Mariana; Dias-Carvalho, Ana; Reis-Mendes, Ana; Ferreira, Rita; Fernandes, Eduarda; Sá, Susana I; Sá SI; Capela, João Paulo; Carvalho, Félix; Costa, Vera Marisa. "Evaluation of mitoxantrone neurotoxicity in CD-1 mice: A chemobrain study". Paper presented in AIMS Meeting, 2022.
  29. Reis-Mendes, A.; Padrão, A.I.; Duarte-Araújo, M; Duarte, JA; Gonçalves-Monteiro, Salomé; Remião, Fernando; Carvalho, Félix; et al. "Involvement of inflammation in DOX-induced cardiotoxicity: an in vivo study". Paper presented in 56th Congress of the European Societies of Toxicology - Eurotox 2021, 2021.
  30. Dias-Carvalho, Ana; Ferreira, Mariana; Fernandes, Ana; Reis-Mendes, Ana; Araújo, Ana Margarida; Ferreira, Rita; Carvalho, Félix; et al. "A neurotoxicidade de longo prazo da doxorrubicina no cérebro de ratinhos CD-1 adultos.". Paper presented in 3º Encontro Nacional de Jovens Investigadores em Oncologia, Porto, Portugal, 2021.
  31. Malheiro, Rui; Carmo, Helena; Carvalho, Félix; Silva, João Pedro. "In vitro evaluation of the effects of the synthetic cannabinoids ADB-FUBINACA and AMB-FUBINACA on mitochondrial function during neurodifferentiation. (SENIOR AUTHOR)". Paper presented in EUROTOX2021 - 56th Virtual Congress of the European Societies of Toxicology, 2021.
  32. Marques, Sandra; Carmo, Helena; Carvalho, Félix; Silva, João Pedro. "Varenicline increases histone H3 acetylation, while affecting global DNA methylation on differentiated SH-SY5Y neuroblastoma cells. (SENIOR AUTHOR)". Paper presented in EUROTOX2021 ¿ 56th Virtual Congress of the European Societies of Toxicology, 2021.
  33. Dias-Carvalho, Ana; Ferreira, Mariana; Fernandes, Ana; Reis-Mendes, Ana; Araújo, Ana Margarida; Ferreira, Rita; Carvalho, Félix; et al. Corresponding author: Dias-Carvalho, Ana. "The neurotoxicity of doxorubicin in the brain of adult CD-1 mice". Paper presented in Ciência 2021 ¿ Science and Technology in Portugal Summit, Lisbon, Portugal, 2021.
  34. Malheiro, Rui; Carmo, Helena; Carvalho, Félix; Silva, João Pedro. "The synthetic cannabinoids ADB-FUBINACA and THJ-2201 affect mitochondrial function during neuronal differentiation of NG108-15 cells at human-relevant concentrations. (SENIOR AUTHOR)". Paper presented in Jornadas Ibéricas de Toxicologia (virtual meeting), 2021.
  35. Dias-Carvalho, Ana; Fernandes, Ana Olivía ; Reis-Mendes, Ana; Duarte-Araújo, Margarida; Carvalho, Félix; Capela, João Paulo; Sá, Susana Isabel; Costa, Vera Marisa. "Chemobrain: assessing the potential to recovery from doxorubicin-induced-neurotoxic effects in CD-1 mice". Paper presented in 14º Encontro de Investigação Jovem da U. Porto (IJUP ¿21), 2021.
  36. Ferreira, Mariana; Dias-Carvalho, Ana; Reis-Mendes, Ana; Carvalho, Félix; Ferreira, Rita; Costa, Vera. "Evaluation of doxorubicin and mitoxantrone neurotoxicity in CD-1 mice: A chemobrain study". Paper presented in 14th Meeting of young researches of U. Porto (IJUP ¿21), 2021.
  37. Ferreira, Mariana; Dias-Carvalho, Ana; Reis-Mendes, Ana; Carvalho, Félix; Ferreira, Rita; Costa, Vera. "Doxorubicin and mitoxantrone neurotoxicity in CD-1 mice: A chemobrain study". Paper presented in XII Biochemistry Day, 2021.
  38. Malheiro, Rui F.; Gomes, Telma M; Galani, M; Dias da Silva, Diana; Carmo, Helena; Carvalho, Félix; Silva, Joao Pedro; et al. Corresponding author: Silva, Joao Pedro. "ADB-FUBINACA, a synthetic cannabinoid, enhances in vitro neuronal differentiation at biologically relevant concentrations". Paper presented in Society of Toxicology (SOT) Virtual Annual Meeting, 2021.
  39. Ana Dias Carvalho; Ana Reis-Mendes; Margarida Duarte-Araújo; Maria de Lourdes Bastos; Carvalho, Félix; Sá, Susana I; Sá SI; Capela, João Paulo; Costa, Vera Marisa. "Chemobrain: evaluation of doxorubicin and mitoxantrone neurotoxicity in cd-1 mice". Paper presented in SPF Meeting 2021 - Sociedade Portuguesa de Farmacologia, 2021.
  40. Dias-Carvalho, Ana; Ferreira, Mariana; Fernandes, Ana; Reis-Mendes, Ana; Araújo, Ana Margarida; Ferreira, Rita; Carvalho, Félix; et al. Corresponding author: Dias-Carvalho, Ana. "The long-term neurotoxicity of doxorubicin in the brain of adult CD-1 mice". Paper presented in Congress of the European Societies of Toxicology (EUROTOX Congress 2021), 2021.
  41. Sá, Susana I; Sá SI; Ana Dias Carvalho; Ana Reis-Mendes; Margarida Duarte-Araújo; Carvalho, Félix; Maria de Lourdes Bastos; Capela, João Paulo; Costa, Vera Marisa. "Evaluation of doxorubicin and mitoxantrone neurotoxicity in cd-1 mice". Paper presented in SIFFUP - Simpósio de Investigação da FFUP, 2020.
  42. Araújo, Ana Margarida; Márcia Cláudia Dias de Carvalho; Costa, Vera Marisa; Duarte, José Alberto; Dinis-Oliveira, Ricardo Jorge; Bastos, Maria de Lourdes; de Pinho, Paula Guedes; Carvalho, Félix. "Application of in vivo metabolomics to evaluate the early pathways of toxicity triggered by human-relevant doses of 3,4-methylenedioxypyrovalerone (MDPV)". Paper presented in 16th Annual Conference of Metabolomics Society - Metabolomics Online 2020, 2020.
  43. Carvalho, Ana Rita; Reis-Mendes, Ana; Duarte-Araujo, Margarida; Carvalho, Félix; Bastos, Maria de Lourdes; Capela, João Paulo; Sá, Susana I; et al. "Neurotoxicidade da mitoxantrona e doxorrubicina: estudo in vivo em diferentes idades". Paper presented in 2º Encontro Nacional de Jovens Investigadores em Oncologia, 2020.
  44. Rouxinol, Daniela; Dias da Silva, Diana; Silva, João Pedro; Bastos, Maria de Lourdes; Carvalho, Félix; Carmo, Helena. "Gas Chromatography¿Mass Spectrometry (GC¿MS) for analysis of biodistribution and metabolic profile of 3,4-dimethylmethcathinone (3,4- DMMC) in Wistar rats". Paper presented in 15th YES (Young European Scientist) Meeting ¿ Digital Experience, 2020.
  45. Dias-Carvalho, Ana; Fernandes, Ana Olivía ; Reis-Mendes, Ana; Duarte-Araújo, Margarida; Carvalho, Félix; Capela, João Paulo; Sá, Susana Isabel; Costa, Vera Marisa. "Doxorubicin Increases Apoptotic Markers in the hipocampal formation of CD-1 mice". Paper presented in VI jornadas da Bioquímica: ¿O passaporte para a inovação¿, 2020.
  46. Ana Dias Carvalho; Ana Reis-Mendes; Margarida Duarte-Araújo; Carvalho, Félix; Sá, Susana I; Sá SI; Capela, João Paulo; Costa, Vera Marisa; et al. "The effects of doxorubicin and mitoxantrone in mice brain at different aging stages: an in vivo chemobrain study". Paper presented in SPF 2020 ¿ Reunião Anual da Sociedade Portuguesa de Farmacologia, 2020.
  47. Freitas, Marisa; Sousa, Adelaide; Soares, Tânia; Ribeiro, Daniela; Carvalho, Félix; Fernandes, Eduarda. "The role of calcium in silver nanoparticles-induced human neutrophils¿ oxidative burst". Paper presented in SOT 59th Annual Meeting, 2020.
  48. Dias da Silva, Diana; Silva, João Pedro; Carmo, Helena; Bastos, Maria de Lourdes; Carvalho, Félix; Dias da Silva, Diana; Carvalho, Félix; Silva, João Pedro. "Pharmacokinetics and pharmacodynamics of the synthetic cannabinoid UR-144 and its halogenated analogue 5F-UR-144 (XLR-11)". Paper presented in 3ª Conferência Europeia sobre Comportamentos e Dependências Aditivas subordinada ao tema ¿The future of addictions ¿ new frontiers for policy, practice and science, 2019.
  49. Rouxinol, Daniela; Dias da Silva, Diana; Silva, João Pedro; Carvalho, Félix; Bastos, Maria de Lourdes; Carmo, Helena. "Review: the newly emerged designer psychostimulant 3,4-dimethylmethcathinone (3,4-DMMC)". Paper presented in 3ª Conferência Europeia sobre Comportamentos e Dependências Aditivas subordinada ao tema ¿The future of addictions ¿ new frontiers for policy, practice and science¿, 2019.
  50. Dias da Silva, Diana; Roque Bravo, Rita; Duarte de Almeida, Tomás; Valente, Maria João; Ferreira, Bárbara; Rebelo, RIta; Carvalho, Félix; Bastos, Maria de Lourdes; Carmo, Helena. Corresponding author: Dias da Silva, Diana. "The in vitro hepatotoxicity of the new recreational drug 3-methylmethcathinone (3-MMC) involves autophagy and apoptosis". Paper presented in Lisbon Addcitions 2019: 3rd European Conference on Addicted Behaviours and Dependencies, 2019.
  51. Roque Bravo, Rita; Carmo, Helena; Silva, João Pedro; Carvalho, Félix; Bastos, ML; Dias da Silva, Diaa. "Insights into benzo fury toxicity: 5-(2-aminopropyl)benzofuran and 6-(2-aminopropyl)benzofuran disrupt oxidative, energetic and mitochondrial homeostasis of hepatocytes in vitro.". Paper presented in Lisbon Addictions 2019, 2019.
  52. Rouxinol, D; Dias da Silva, Diana; Silva, João Pedro; Carvalho, Félix; Bastos, ML; Carmo, Helena. "The newly emerged designer psychostimulant 3,4-dimethylmethcathinone (3,4-DMMC)". Paper presented in Lisbon Addictions 2019, 2019.
  53. Faria, Ana Carolina; Dias da Silva, Diana; Silva, João Pedro; Carvalho, Félix; Bastos, Maria de Lourdes; Carmo, Helena. "Hyponatraemia induced by synthetic phenethylamines.". Paper presented in The 3rd European Conference on Addictive Behaviours and Dependencies (Lisbon Addictions 2019), 2019.
  54. Rodrigues, Daniela; Costa, Vera M; Bastos, Maria De Lourdes; Carvalho, Félix. "Effects of alpha-amanitin in HepG2 cells are not prevented by drugs used in Amanita phalloides intoxications". Paper presented in EUROTOX 2019 - 55th Annual Meeting of the Society of the European Toxicology Society, 2019.
  55. Araújo, Ana Margarida; Enea, Maria; Fernandes, Eduarda; Bastos, Maria de Lourdes; Carvalho, Félix; Guedes de Pinho, Paula; Carvalho, Márcia. "A new strategy for exploring the role of hyperthermia in MDMA-induced toxicity in primary mouse hepatic cells using GC-MS-based metabolomics". Paper presented in 55th European Congress of the European Societies of the Toxicology (EUROTOX2019), 2019.
  56. Dionísio, Flávio; Duarte-Araújo, Margarida; de Lourdes Bastos, Maria; Carvalho, Félix; Costa, Vera Marisa. "The Main Metabolites of Cyclophosphamide, 4-Hydroxycyclophosphamide and Acrolein, are Cardiotoxic at Relevant Clinical Concentrations". Paper presented in 14th Young European Scientist Meeting, 2019.
  57. Faria, AC; Carmo, Helena; Teixeira, C; Rouxinol, D; Silva, João Pedro; Carvalho, Félix; Bastos, ML; et al. "Administration of 3,4-dimethylmethcathinone (3,4-DMMC) and methylone increases the release of antidiuretic hormone in female Wistar rats". Paper presented in EUROTOX2019, 2019.
  58. Rouxinol, D; Dias da Silva, Diana; Teixeira, C; Faria, AC; Silva, João Pedro; Carvalho, Félix; Bastos, ML; Carmo, Helena. "Biodistribution of the new psychoactive stimulant 3,4-dimethylmethcathinone (3,4-DMMC) in Wistar rats assessed by gas chromatography-mass spectrometry (GC-MS)". Paper presented in EUROTOX2019, 2019.
  59. Alexandre, JA; Malheiro, RM; Dias da Silva, Diana; Carmo, Helena; Carvalho, Félix; Silva, João Pedro. "Synthetic cannabinoids 5F-PB22 and THJ-2201 promote in vitro CB1 receptor-dependent neuronal differentiation at in vivo-relevant concentrations. (SENIOR AUTHOR)". Paper presented in EUROTOX2019, 2019.
  60. Carvalho, Ana Rita; Reis-Mendes, Ana Filipa; Duarte-Araujo, Margarida; Guedes, Rita; Gonçalves-Monteiro, Salomé; Carvalho, Félix; Bastos, Maria de Lourdes; Capela, João Paulo; Costa, Vera M. "Doxorubicin and mitoxantrone effects on the brain of differently aged mice: an in vivo chemobrain study". Paper presented in 55th Annual Meeting of the Society of the European Toxicology Society - EUROTOX 2019, 2019.
  61. Araújo, Ana Margarida; Fernandes, Eduarda; Bastos, Maria de Lourdes; Carvalho, Félix; Guedes de Pinho, Paula; Carvalho, Márcia. "Use of metabolomics for exploring early mechanisms of hepatotoxicity triggered by amphetamine-like drugs". Paper presented in 15th Annual Conference of Metabolomics Society (Metabolomics 2019), 2019.
  62. Rodrigues, Daniela; Costa, Vera M; Bastos, Maria de Lourdes; Carvalho, Félix. "N-Acetylcysteine, silibinin and benzylpenicillin do not confer protection against a-amanitin cytotoxicity in HepG2 and HepaRG cells". Paper presented in 58th Annual Meeting of the Society of Toxicology, Baltimore, Maryland, EUA, 2019.
  63. Fernandes, Eduarda; Rufino, Ana; Ferreira de Oliveira, Miguel; Ribeiro, Daniela; Sousa, Adelaide; Soares, Tânia; Gónzalez-Gómez, M.; et al. "Testing the Effects of Silver Nanoparticles in In Vitro Models of Intestinal Toxicity and Inflammation". Paper presented in 10th International Conference ¿Biomaterials and Nanobiomaterials: Recent Advances Safety-Toxicology and Ecological Issus¿, 2019.
  64. Roque Bravo, Rita; Carmo, Helena; Carvalho, Félix; Bastos, Maria de Lourdes; Dias da Silva, Diana. "Toxicity of butylone, buphedrone and 3,4-dimethylmethcathinone (3,4-DMMC) in in vitro hepatocyte models.". Paper presented in VII Annual Meeting of the Portuguese Society for the Study of Abused and Neglected Children (SPECAN), IV Annual Meeting of the Portuguese Association of Forensic Sciences (APCF) and Scientific Conferences of Sciences of the University Institute of Health, 2019.
  65. Teixeira, Catarina; Carmo, Helena; Rouxinol, Daniela; Faria, Ana Carolina; Carvalho, Félix; Bastos, Maria de Lourdes; Dias da Silva, Diana. "3,4-DIMETHYLMETHCATHINONE (3,4-DMMC) AND METHYLONE AFFECT ENERGY LEVELS AND OXIDATIVE PARAMETERS IN DIFFERENT ORGANS OF WISTAR RATS". Paper presented in IV Congresso da Associação Portuguesa de Ciências Forenses e XI Jornadas Científicas do Departamento de Ciências do Instituto Universitário de Ciências da Saúde, 2019.
  66. Rouxinol, Daniela; Dias da Silva, Diana; Teixeira, Catarina; Faria, Ana Carolina; Carvalho, Félix; Bastos, Maria de Lourdes; Carmo, Helena. "GAS CHROMATOGRAPHY-MASS SPECTROMETRY (GC-MS) METHOD FOR THE ASSESSMENT OF THE BIODISTRIBUTION PROFILE OF THE NEW PSYCHOSTIMULANT 3,4-DIMETHYLMETHCATHINONE (3,4-DMMC) IN WISTAR RATS". Paper presented in IV Congresso da Associação Portuguesa de Ciências Forenses e XI Jornadas Científicas do Departamento de Ciências do Instituto Universitário de Ciências da Saúde, 2019.
  67. Dias da Silva, Diana; Roque Bravo, Rita; Duarte de Almeida, Tomás; Valente, Maria João; Ferreira, Bárbara; Rebelo, Rita; Carvalho, Félix; Bastos, Maria de Lourdes; Carmo, Helena. Corresponding author: Dias da Silva, Diana. "Assessment of the potential hepatotoxicity of the psychostimulant 3- methylmethcathinone (3-MMC), using primary rat hepatocytes". Paper presented in VII Annual Meeting of the Portuguese Society for the Study of Abused and Neglected Children (SPECAN), IV Annual Meeting of the Portuguese Association of Forensic Sciences (APCF) and Scientific Conferences of Sciences of the University Institute of Health, 2019.
  68. Faria, Ana Carolina; Carmo, Helena; Teixeira, Catarina; Rouxinol, Daniela; Carvalho, Félix; Bastos, Maria de Lourdes; Dias da Silva, Diana. "Increased release of antidiuretic hormone (ADH) following administration of cathinone analogues in female Wistar rats.". Paper presented in IV Congress of the Portuguese Association of Forensic Sciences, 2019.
  69. Ribeiro, Daniela; Freitas, Marisa; Carvalho, Félix; Fernandes, Eduarda (presenter). "The extended effects of thapsigargin on human neutrophils¿ calcium pathways". Paper presented in SOT 58th Annual Meeting and ToxExpo, 2019.
    10.1145/633292.633402
  70. Dias-Carvalho, Ana; Reis-Mendes, Ana; Duarte-Araújo, Margarida; Guedes, Rita; Gonçalves-Monteiro, Salomé; Carvalho, Félix; Bastos, Maria Lourdes; Capela, João Paulo; Costa, Vera Marisa. "Differential effects of doxorubicin and mitoxantrone in the brain redox status of differently aged mice". Paper presented in 10th Annual International (bio)Medical Students Meeting, 2019.
  71. Costa, Vera M; Capela, João Paulo; Silveira, CM; Rodrigues, Patrícia; Eleutério, Rute; Dores-Sousa, José Luís; Carvalho, Rui A; et al. "Mitoxantrone prompts early energetic and proteomic changes in HL-1 cardiomyocytes and late oxidative stress in clinically relevant doses.". Paper presented in 58th Annual Meeting of the Society of Toxicology, Baltimore, Maryland, EUA, 2019.
  72. Faria, Ana Carolina; Carmo, Helena; Carvalho, Félix; Bastos, Maria de Lourdes; Dias da Silva, Diana. "Drug-induced hyponatraemia: the case of synthetic cathinones.". Paper presented in 17th National Congress of Forensic Medicine and Forensic Sciences, 2018.
  73. Carvalho, Ana Rita; Reis-Mendes, Ana Filipa; Duarte-Araújo, Margarida; Guedes, Rita; Gonçalves-Monteiro, Salomé; Carvalho, Félix; Bastos, Maria de Lourdes; Capela, João Paulo; Costa, Vera M. "The effects of doxorubicin and mitoxantrone in brain glutathione levels of differently aged mice". Paper presented in Translational Research at iMed Conference® 10.0 | Lisboa 2018, Lisboa, Portugal, 2018.
  74. Rocha-pereira, C.; Silva, Renata; Soares, Jorge; Casanova, Alfredo G.; Carmo, Helena; Carvalho, Félix; Bastos, Maria de Lourdes; Remião, Fernando. "TOX-OER MOOC: learning toxicokinetics and liver as target organ of xenobiotics.". Paper presented in IPAP18 ¿ Salamanca. Innovation in Pharmacy: Advances and Perspectives. 24th ¿ 28th September 2018, Salamanca, Spain., 2018.
  75. Pedro Nicola; Marisa Freitas; Sónia Rocha; Félix Carvalho; Eduarda Fernandes; Daniela Ribeiro; Eduarda das Graças Rodrigues Fernandes; et al. "Optimization of a synaptosomal model to study the effect of carotenoids in the peroxynitrite - induced lipid peroxidation". Paper presented in YES (Young European Scientist) Meeting, 2018.
  76. Araújo, Ana Margarida; Bastos, Maria de Lourdes; Fernandes, Eduarda; Carvalho, Félix; Carvalho, Márcia; Guedes de Pinho, Paula. "Characterization of hepatic metabolic disturbances caused by subtoxic levels of 3,4-methylenedioxymethamphetamine (MDMA)". Paper presented in UCIBIO Annual Meeting, 2018.
  77. Alexandre, JA; Carmo, Helena; Carvalho, Félix; Silva, João Pedro; Parra, J; Araújo, ARTS. "Synthetic cannabinoids enhance neuronal differentiation in neuroblastoma cells at in vivo relevant concentrations. (SENIOR AUTHOR)". Paper presented in EUROTOX2018 ¿ 54th Congress of the European Societies of Toxicology, 2018.
  78. Reis-Mendes, Ana; Carvalho, Félix; Sousa, Emília; Bastos, Maria de Lourdes; Costa, Vera M. "Cardiotoxicity of FAC (5-Fluorouracil + Adriamycin + Cyclophosphamide) Metabolites in H9c2 Cardiac Differentiated Cells". Paper presented in 54th Congress of European Societies of Toxicology, (Eurotox 2018) Brussels, Belgium, 2018.
  79. Soares, Jorge; Costa, Vera M; Bronze, Susana; Gaspar, Helena; Santos, Susana; Bastos, Maria De Lourdes; Carvalho, Félix; Capela, João Paulo. "Neurotoxicity of synthetic cathinones and evaluation of putative neuroprotectors". Paper presented in Innovations in Pharmacy. Advances & perspectives (IPAP18), Salamanca, Spain, 2018.
  80. Nicola, Pedro (presenter); Freitas, Marisa; Rocha, Sónia; Carvalho, Félix; Fernandes, Eduarda; Ribeiro, Daniela. "Synaptosomes as lipid models to study the inhibition of peroxynitrite - induced lipid peroxidation". Paper presented in Italian Spanish-Portuguese Joint Meeting in Medicinal Chemistry - MedChemSicily2018, 2018.
  81. Reis-Mendes, Ana; Carvalho, Félix; Sousa, Emília; Bastos, Maria de Lourdes; Costa, Vera M. "Main metabolites of 5-fluorouracil + adriamycin + cyclophosphamide (FAC) are not major contributors to FAC toxicity in H9c2 cardiac differentiated cells". Paper presented in International Symposium - MitoPorto - mitochondrial evolution, metabolism and disease, Porto, Portugal, 2018.
  82. Eira, SG; Carmo, Helena; Carvalho, Félix; Silva, João Pedro. "Role of cannabinoids in neuronal development. (SENIOR AUTHOR)". Paper presented in Jornadas Científicas do Instituto Universitário de Ciências da Saúde (CESPU), 2018.
  83. Sousa, Daniela; Enea, Maria; Carmo, Helena; Carvalho, Félix; Bastos, Maria de Lourdes; Guedes de Pinho, Paula; Dias da Silva, Diana. "TOXICITY OF THE FAT BURNER 2,4-DINITROPHENOL (2,4-DNP) IN PRIMARY RAT HEPATOCYTES". Paper presented in XII Jornadas Científicas de Ciências do Instituto Universitário de Ciências da Saúde (IUCS-CESPU) e III Encontro Anual da Associação Portuguesa de Ciências Forenses (APCF), 2018.
  84. Ferreira, Bárbara; Dias da Silva, Diana; Carvalho, Félix; Bastos, Maria de Lourdes; Carmo, Helena. "A REVIEW ON THE NOVEL PSYCOACTIVE SUBSTANCE 3-METHYLMETHCATHINONE (3-MMC)". Paper presented in XII Jornadas Científicas de Ciências do Instituto Universitário de Ciências da Saúde (IUCS-CESPU) e III Encontro Anual da Associação Portuguesa de Ciências Forenses (APCF), 2018.
  85. Faria, Ana Carolina; Carmo, Helena; Carvalho, Félix; Bastos, Maria de Lourdes; Dias da Silva, Diana. "HYPONATRAEMIA INDUCED BY SYNTHETIC CATHINONES". Paper presented in XII Jornadas Científicas de Ciências do Instituto Universitário de Ciências da Saúde (IUCS-CESPU) e III Encontro Anual da Associação Portuguesa de Ciências Forenses (APCF), 2018.
  86. Rouxinol, Daniela; Dias da Silva, Diana; Carvalho, Félix; Bastos, Maria de Lourdes; Carmo, Helena. "INTRACELLULAR MECHANISMS UNDERLYING THE TOXICITY OF SYNTHETIC CATHINONES". Paper presented in XII Jornadas Científicas de Ciências do Instituto Universitário de Ciências da Saúde (IUCS-CESPU) e III Encontro Anual da Associação Portuguesa de Ciências Forenses (APCF), 2018.
  87. Silva, Sara; Enea, Maria; Carvalho, Félix; Bastos, Maria de Lourdes; Carmo, Helena; Dias da Silva, Diana. "HYPERTHERMIA EXACERBATES THE CARDIOTOXICITY OF BENZYLPIPERAZINE (BZP) AND METHYLENEDIOXYMETHAMPHETAMINE (MDMA) COMBINATIONS IN H9C2 CELLS". Paper presented in XII Jornadas Científicas de Ciências do Instituto Universitário de Ciências da Saúde (IUCS-CESPU) e III Encontro Anual da Associação Portuguesa de Ciências Forenses (APCF), 2018.
  88. Martins, Maria João; Roque Bravo, Rita; Enea, Maria; Carmo, Helena; Carvalho, Félix; Bastos, Maria de Lourdes; Dinis-Oliveira, Ricardo Jorge; Dias da Silva, Diana. "COCAINE AND ETHANOL ADDITIVELY IMPAIR OXIDATIVE, ENERGETIC AND MITOCHONDRIAL HOMEOSTASIS IN H9C2 CARDIOMYOCYTES". Paper presented in XII Jornadas Científicas de Ciências do Instituto Universitário de Ciências da Saúde (IUCS-CESPU) e III Encontro Anual da Associação Portuguesa de Ciências Forenses (APCF), 2018.
  89. Faria, Ana Carolina; Carmo, Helena; Carvalho, Félix; Bastos, Maria de Lourdes; Dias da Silva, Diana. "Hyponatraemia: a potential life threatening consequence of cathinones abuse.". Paper presented in III Congress of the Portuguese Association of Forensic Sciences, 2018.
  90. Roque Bravo, Rita; Moreira, Patricia; Carmo, Helena; Carvalho, Félix; Bastos, Maria de Lourdes; Dias da Silva, Diana. "4-Fluoromethamphetamine exerts toxicity to hepatocellular in vitro models via CYP450-mediated metabolism.". Paper presented in VI Annual Meeting of the Portuguese Society for the Study of Abused and Neglected Children (SPECAN), III Annual Meeting of the Portuguese Association of Forensic Sciences (APCF) and Scientific Conferences of Sciences of the University Institute of Health, 2018.
  91. Alves, Marisa; Reis-Mendes, Ana; Carvalho, Félix; Remião, Fernando; Bastos, Maria Bastos; Costa, Vera M. "An in vitro study with differentiated and non-differentiated H9c2 cells to evaluate pixantrone cardiotoxicity". Paper presented in 11st Meeting of young researchers of University Porto (IJUP ¿18), Porto, Portugal, 2018.
  92. Loureiro, Sara; Costa, Vera M; Duarte, José Alberto; Duarte-Araújo, Margarida; Gonçalves-Monteiro, Salomé; Bastos, Maria de Lourdes; Carvalho, Félix; Capela, João Paulo. "Methylphenidate evokes heart and kidney toxicity in adolescent rats exposed one-week to relevant oral doses". Paper presented in Lisbon Addictions 2017, Lisboa, Portugal, 2017.
  93. Martins, Maria João; Moreira, Patricia; Roque Bravo, Rita; Carmo, Helena; Carvalho, Félix; Bastos, Maria de Lourdes; Dinis-Oliveira, Ricardo Jorge; Dias da Silva, Diana. "Oxidative damage and energetic crisis in cardiomyocytes after co-exposure of cocaine and morphine". Paper presented in LIII Congress of the European Toxicology Society (EUROTOX), 2017.
  94. Faria, Juliana; Barbosa, Joana; Leal, S; Afonso, L. P.; Lobo, J.; Moreira, Roxana; Queiros, Odilia; Carvalho, Félix; Dinis-Oliveira, Ricardo Jorge. "Tramadol and tapentadol cause brain, lung and heart toxicity in effective and maximum tolerated doses". Paper presented in EUROTOX Congress, 2017.
  95. Barbosa, Joana; Faria, Juliana; Leal, S; Afonso, L. P.; Lobo, J.; Moreira, Roxana; Queiros, Odilia; Carvalho, Félix; Dinis-Oliveira, Ricardo Jorge. "Acute administration of tramadol and tapentadol induces dose-dependent hepato and nephrotoxicity in wistar rats". Paper presented in EUROTOX Congress, 2017.
  96. Araújo, Ana Margarida; Lima, Ana Rita; Bastos, Maria de Lourdes; Carvalho, Félix; Carvalho, Márcia; Guedes de Pinho, Paula. "Effect of subtoxic and toxic concentrations of galactosamina in the metabolome of primary mouse hepatocytes". Paper presented in 53rd European Congress of the European Societies of the Toxicology (EUROTOX2017), 2017.
  97. Bárbara Ferreira; Rebelo, Rita; Patrícia Moreira; Carvalho, Félix; Diana Dias da Silva; Carmo, Helena. "Cytotoxicity of 3-methylmethcathinone (3-MMC or metaphedrone) in primary rat hepatocytes." Poster communication presented by Bárbara Ferreira at II Congress of Portuguese Association of Forensic Sciences, Porto, Portugal. March 30th-31st, 2017.". Paper presented in II Congress of Portuguese Association of Forensic Sciences, 2017.
  98. Roque Bravo, Rita; Moreira, Patricia; Martins, Maria João; Carvalho, Félix; Bastos, Maria de Lourdes; Carmo, Helena; Dias da Silva, Diana. Corresponding author: Roque Bravo, Rita. "In vitro hepatotoxicity of two new psychoactive benzofurans (5-APB and 6-APB) used as recreational drugs". Paper presented in VI Annual Meeting of the Portuguese Society for the Study of Abused and Neglected Children (SPECAN), III Annual Meeting of the Portuguese Association of Forensic Sciences (APCF) and Scientific Conferences of Sciences of the University Institute of Health, 2017.
  99. Martins, Maria João; Moreira, Patricia; Roque Bravo, Rita; Carmo, Helena; Carvalho, Félix; Bastos, Maria de Lourdes; Dinis-Oliveira, Ricardo Jorge; Dias da Silva, Diana. "Ethanol additively enhanced cardiotoxicity of cocaine in vitro through oxidative damage and energetic deregulation.". Paper presented in V Annual Meeting of the Portuguese Society for the Study of Abused and Neglected Children (SPECAN), III Annual Meeting of the Portuguese Association of Forensic Sciences (APCF) and Scientific Conferences of Sciences of the University Institute of Health S, 2017.
  100. Pinho, Rita; Almeida, Daniela; Soares, Jorge; Bastos, Maria de Lourdes; Carvalho, Félix; Capela, João Paulo; Costa, Vera M. "Mitoxantrone was more neurotoxic than doxorubicin in SH-5YSY human cells". Paper presented in 10th Meeting of young researchers of University Porto (IJUP ¿17), Porto, Portugal, 2017.
  101. Valente, Maria João; Araújo, Ana Margarida; Silva, Renata; Amaral, Cristina; Silva, Georgina; Duarte, José Alberto; Fernandes, Eduarda; et al. "In vitro toxicity of ß-keto amphetamines mechanistic studies in hepatic and neuronal cell models". Paper presented in UCIBIO Advisory Board Member, 2017.
  102. Ferreira, Bárbara; Dias-da-Silva, Diana; Rebelo, Rita; Moreira, Patricia; Carvalho, Félix; Bastos, Maria Lurdes; Carmo, Helena; et al. "Citotoxicity of 3-methylmethcathinone (3-MMC or metaphedrone) in primary rat hepatocytes". Paper presented in II Congresso da Associação Portuguesa de Ciências Forenses e as Jornadas Científicas do Departamento de Ciências do Instituto Universitário de Ciências da Saúde, Porto, Portugal, 2017.
  103. Roque Bravo, Rita; Martins, Maria João; Pinto, Ana Cristina; Valente, Maria João; Carvalho, Félix; Bastos, Maria da Lourdes; Carmo, Helena; Dias da Silva, Diana. "Emerging club drugs: in vitro hepatotoxicity of six synthetic cathinones and benzofurans". Paper presented in LIII Congress of the European Toxicology Society (EUROTOX), 2016.
  104. Neves, João; Soares, José; Alves, Emanuele; Cravo, Sara; Silva, Artur; Afonso, Carlos; Netto, Aníbal; Carvalho, Félix; Dinis-Oliveira, Ricardo. "The homemade drug "Krokodil": chromatographic and spectroscopy studies". Paper presented in IJUP 2016, 2016.
  105. Valente, Maria João; Bastos, Maria de Lourdes; Carvalho, Félix; Guedes de Pinho, Paula; Carvalho, Márcia. "ßk-amphetamines: neurotoxicity triggered by methylone and MDPV in undifferentiated and differentiated SH-SY5Y cells and comparison to MDMA". Paper presented in 52nd European Congress of the European Societies of the Toxicology (EUROTOX 2016), 2016.
  106. Valente, Maria João; Araújo, Ana Margarida; Bastos, Maria de Lourdes; Fernandes, Eduarda; Carvalho, Félix; Guedes de Pinho, Paula; Carvalho, Márcia. "Characterization of hepatotoxicity mechanisms triggered by synthetic cathinones". Paper presented in UCIBIO - Encontro CIÊNCIA 2016, 2016.
  107. Bastos, Maria de Lourdes; Valente, Maria João; Araújo, Ana Margarida; Carvalho, Félix; Guedes de Pinho, Paula; Carvalho, Márcia. "Synthetic cathinones: Unveiling the mechanisms for liver injury". Paper presented in Society of Toxicology¿s 55th Annual Meeting, New Orleans, Louisiana, USA, 2016.
  108. Moreira, Patricia; Cunha, Sara; Dias-da-Silva, Diana; Carvalho, Félix; Basto, Maria Lurdes; Carmo, Helena. "Development and validation of a method for the simultaneous determination of two piperazines used as drugs of abuse". Paper presented in EUROTOX2016, Seville, Spain, 2016.
  109. Dias-da-Silva, Diana; Moreira, Patricia; Silva, Maria João; Carvalho, Félix; Bastos, Maria Lurdes; Carmo, Helena. "In vitro hepatotoxicity of mixtures of benzylpiperazine (BZP) and 3-trifluoromethylphenylpiperazine (TFMPP)". Paper presented in SOT Annual Meeting - Society of Toxicology, New Orleans, USA, 2016.
  110. Reis-Mendes, Ana; Gomes, Ana Sara; Carvalho, R.A.; Remião, Fernando; Carvalho, Félix; Pinto, Madalena; Bastos, Maria de Lourdes; Sousa, Emília; Costa, Vera. "The cardiotoxicity of mitoxantrone: A comparative in vitro study between mitoxantrone and its naphthoquinoxaline metabolite". Paper presented in IJUP¿15 ¿ 8th Meeting of Your Researchers of the University of Porto, 2015.
  111. Bastos, Maria de Lourdes; Valente, Maria João; Araújo, Ana Margarida; Carvalho, Félix; Guedes de Pinho, Paula; Carvalho, Márcia. "Hyperthermia exacerbates MDPV-induced hepatic oxidative stress". Paper presented in Society of Toxicology¿s 54th Annual Meeting, San Diego, California, USA, 2015.
  112. Alves, Emanuele; Ferreira, Ana Sofia Agonia; Neves, João; Soares, José; Cravo, Sara; Afonso, Carlos; Netto, Aníbal; Carvalho, Félix; Dinis, Ricardo. "Synthesis of the ¿Krokodil¿ drug through ¿street¿ reported methods, and product analysis.". Paper presented in 53 rd The International Association of Forensic Toxicologists (TIAFT), Florence, Italy., 2015.
  113. Viana SD; Valero, Jorge; Rodrigues-Santos, Paulo; Couceiro, Patrícia; Silva, Andréa M.; Carvalho, Félix; Ali, Syed F.; Fontes Ribeiro, C.A.; Pereira, F.C.. "EnRAGEd pre-gliotic striatal astrocytes in MPTP mice". Paper presented in VII Annual Meeting of IBILI ¿New trends in biomedical research¿, 2015.
  114. Alves, Emanuele; Soares, José; Ferreira, AS; Cravo, Sara; Afonso, Carlos; Netto, Aníbal; Carvalho, Félix; Dinis-Oliveira, Ricardo Jorge. "The chemistry behind ¿krokodil¿: street-like synthesis and product analysis". Paper presented in 4º Encontro de Doutorandos da FMUP, 2014.
  115. Alves, Emanuele; Soares, José; Ferreira, AS; Afonso, Carlos; Netto, Aníbal; Carvalho, Félix; Dinis-Oliveira, Ricardo Jorge. "A síntese ilícita de krokodil.". Paper presented in 1ª Conferência do Instituto Nacional de Medicina Legal e Ciências Forenses, 2014.
  116. Alves, Emanuele; Agonia, A.; Cravo, Sara; Afonso, Carlos; Netto, Aníbal; Bastos, Maria de Lurdes; Carvalho, Félix; Dinis-Oliveira, Ricardo Jorge. "Quantificação de opioides em sangue por Cromatografia Gasosa Acoplada a Espetrometria de Massa usando QuEChERS". Paper presented in 1ª Conferência do Instituto Nacional de Medicina Legal e Ciências Forenses, 2014.
  117. Araújo, Ana Margarida; Valente, Maria João; Dias da Silva, Diana; Carvalho, Márcia; Gaspar, Helena; Carvalho, Félix; Bastos, Maria de Lourdes; Guedes de Pinho, Paula. "Potential hepatotoxicity caused by synthetic cathinones acquired in ¿smartshops¿". Paper presented in IJUP¿2014 - 7º Encontro de Jovens Investigadores da U.PORTO, 2014.
  118. Viana SD; Fernandes, Rosa C.; Canas, Paula M.; Silva, Andréa M.; Camila Portugal; Renato Socodato; Carvalho, Félix; et al. "Unaltered S100B/RAGE axis in dysfunctional striata from MPTP-treated mice.". Paper presented in XVIII Congresso da Sociedade Portuguesa de Bioquímica, 2014.
  119. Viana SD; Fernandes, Rosa C.; Canas, Paula M.; Silva, Andréa M.; Camila Portugal; Renato Socodato; Carvalho, Félix; et al. "The quiet neuronal RAGE in a storming dysfunctional striata under a chronic MPTP challenge". Paper presented in 6th Annual meeting of IBILI, 2014.
  120. Freitas, Marisa (presenter); Costa, V.M.; Ribeiro, Daniela; Couto, Diana; Porto, G.; Carvalho, Félix; Fernandes, Eduarda. "Acetaminophen prevents oxidative burst and delays apoptosis in human neutrophils in vitro". Paper presented in 2nd International Conference on Ocupacional and Environmental Toxicology 2013, 2013.
  121. Araújo, Ana Margarida; Bastos, Maria de Lourdes; Carvalho, Márcia; Carvalho, Félix; Gaspar, Helena; Cardoso Matias, Ana; Guedes de Pinho, Paula. "Chemical characterization of ¿legal highs¿ marketed in Portuguese ¿smartshops¿". Paper presented in 12th National Congress of Legal Medicine and Forensic Sciences, 2013.
  122. Vale, Luís; Valente, Maria João; Carvalho, Jorge; Almeida, Liliana; Afonso, Joana; Morato, Manuela; Carvalho, Félix; et al. "Low-dose acetylsalicylic acid improves the antihypertensive efficacy of losartan in spontaneously hypertensive rats". Paper presented in Trabalho apresentado em IJUP 2013 - 6º Encontro de Jovens Investigadores da U.PORTO, 2013.
  123. Barbosa, Daniel José; Capela, João Paulo; Silva, Renata; Ferreira, Luísa Maria ; Branco, Paula Sério; Fernandes, Eduarda; Bastos, Maria de Lourdes; Carvalho, Félix. "The mixture of "Ecstasy" and its metabolites, at low concentrations, is toxic to SH-SY5Y differentiated cells". Paper presented in 48th Congress of the European Societies of Toxicology (EUROTOX), 2012.
  124. Reina-Couto, Marta; Sousa, Teresa; Morato, Manuela; Carvalho, Jorge; Marques, Marco; Morgado, Luís; Valente, Maria João; et al. "Evaluation of oxidative stress markers in chronic heart failure". Paper presented in Trabalho apresentado em IJUP 2012 - 5º Encontro de Jovens Investigadores da U.PORTO, 2012.
  125. Sousa, Teresa; Afonso, Joana; Valente, Maria João; Carvalho, Jorge; Serrão, Maria Paula; Morato, Manuela; Patinha, Daniela; et al. "Hydrogen peroxide regulates renal production of renin and angiotensinogen in angiotensin II-hypertensive rats". Paper presented in 22nd European Meeting on Hypertension and Cardiovascular Prevention, 2012.
  126. Vieira, David; Gomes, Ana Sara; Sousa, Emília; Afonso, Carlos; Pinto, Madalena; Carvalho, Félix; Santos-Silva, Alice; et al. "Potential mutagenicity of TXA1, a small molecule potent inhibitor of tumor cell growth". Paper presented in Young European Scientist Meeting Guide: YES Meeting, 2010.
  127. Dinis-Oliveira, Ricardo Jorge; Pinho, Paula Guedes; Magalhães, T.; Afonso, Carlos; Remião, Fernando; Bastos, Maria de Lurdes; Carvalho, Félix. "Human postmortem histopathological and toxicokinetic analysis following paraquat intoxications, indicate that traditional therapeutic measures, to eliminate paraquat and to prevent inflammation, need to be refined". Paper presented in XXI Congress of the International Academy if Legal Medicine, Lisbon, 2009.
  128. Nunes, Carla; Sousa, Teresa; Fernandes, Eduarda; Carvalho, Félix; Laranjinha, João; Albino-Teixeira, António. "Direct scavenging of nitric oxide by DPSPX (1,3-dipropyl-8-sulfophenilxantine)". Paper presented in Autumn meeting of the British Pharmacological Society & the Physiological Society with Sociedade Portuguesa de Farmacologia, 2001.
Edited book
  1. Carvalho, Félix. Toxicologia Fundamental. 2018.
    Published • Editor
  2. Carvalho, Félix. Toxicologia Forense. 2015.
    Editor
Journal article
  1. Mariana Ferreira; Patrícia Carneiro; Vera Marisa Costa; Félix Carvalho; Andreas Meisel; João Paulo Capela; Ferreira, Mariana; et al. "Amphetamine and methylphenidate potential on the recovery from stroke and traumatic brain injury: a review". Reviews in the Neurosciences (2024): https://doi.org/10.1515/revneuro-2024-0016.
    Submitted • 10.1515/revneuro-2024-0016
  2. Ana Reis-Mendes; Cláudia Vitorino-Oliveira; Mariana Ferreira; Félix Carvalho; Fernando Remião; Emília Sousa; Maria de Lourdes Bastos; et al. Corresponding author: Costa, Vera M. "Comparative In Vitro Study of the Cytotoxic Effects of Doxorubicin’s Main Metabolites on Cardiac AC16 Cells Versus the Parent Drug". Cardiovascular Toxicology (2024): https://doi.org/10.1007/s12012-024-09829-6.
    Accepted • 10.1007/s12012-024-09829-6
  3. Araújo, Ana Margarida; Marques, Sandra; Guedes de Pinho, Paula; Carmo, Helena; Carvalho, Félix; Silva, João Pedro; Ana Margarida Araújo; et al. Corresponding author: Araújo, Ana Margarida. "Identification of key neuronal mechanisms triggered by dimethyl fumarate in SH-SY5Y human neuroblastoma cells through a metabolomic approach". Archives of Toxicology (2024): https://doi.org/10.1007/s00204-024-03683-9.
    Accepted • 10.1007/s00204-024-03683-9
  4. Carapito, Ângela; Roque, Ana Cecília A.; Carvalho, Félix; Pinto, Joana; Guedes de Pinho, Paula. "Exploiting volatile fingerprints for bladder cancer diagnosis: A scoping review of metabolomics and sensor-based approaches". Talanta 268 (2024): 125296. http://dx.doi.org/10.1016/j.talanta.2023.125296.
    Published • 10.1016/j.talanta.2023.125296
  5. Proença, Carina; Maria Carolina Lobo; Ana T. Rufino; Ferreira de Oliveira, José Miguel P.; Freitas, Marisa; Jenifer Trepiana; Maria P. Portillo; Carvalho, Félix; Eduarda Fernandes. Corresponding author: Proença, Carina. "Evidence of phenolic compounds as modulators of ChREBP and NRF2 in type 2 diabetes: a review of their potential for drug development". (2024):
    Submitted
  6. Carneiro, Patrícia; Ferreira, Mariana; Costa, Vera Marisa; Carvalho, Félix; Capela, João Paulo. "Protective effects of amphetamine and methylphenidate against dopaminergic neurotoxins in SH-SY5Y cells". Current Research in Toxicology (2024):
    Submitted
  7. Vitorino-Oliveira, Cláudia; Kahremany, Shirin; Nisim, Leon; Duarte-Araújo , Margarida; Carvalho, Félix; Gruzman, Arie; Costa, Vera Marisa. "Assessing the cytotoxic effects of sunitinib on AC16 cardiac cells and its potential association with autophagy". (2024): https://doi.org/10.48797/sl.2024.133.
    https://doi.org/10.48797/sl.2024.133
  8. Luís, Cláudia; Vitorino-Oliveira, Cláudia; Gaspar, Helena; Carvalho, Félix; Capela, João Paulo; Costa, Vera Marisa. "Comparing Cytotoxic Effects of Synthetic Cathinones and Methamphetamine on Cardiac AC16 Cell". (2024): https://doi.org/10.48797/sl.2024.251.
    https://doi.org/10.48797/sl.2024.251
  9. Soares-Couto, Patrícia; Costa, Vera Marisa; Dias-Carvalho, Ana; Sá, Susana Isabel; Ferreira, Mariana; Carvalho, Félix; Capela, João Paulo. "Oral methylphenidate effects on GAP43 and PSD95 expression in the developing brains of Wistar Kyoto rats". (2024): https://doi.org/10.48797/sl.2024.195.
    https://doi.org/10.48797/sl.2024.195
  10. Barbosa-Azevedo, Maria; Cardoso, Maria; Carvalho, Félix; Costa, Vera M.. "Anticancer drugs and their impact on chemobrain development: an in vitro investigation". (2024): https://doi.org/10.48797/sl.2024.241.
    https://doi.org/10.48797/sl.2024.241
  11. Roque-Bravo, Rita; Carmo, Helena; Silva, João Pedro; Carvalho, Félix; Dias-da-Silva, Diana. "The effect of synthetic cannabinoid ADB-FUBINACA on primary neuronal cultures ß-galactosidase activity: preliminary findings". (2024): https://doi.org/10.48797/sl.2024.135.
    https://doi.org/10.48797/sl.2024.135
  12. Sousa, Adelaide; Azevedo, Rui; Costa, Vera M.; Oliveira, Sara; Viana, Sofia; Reis, Flávio; Almeida, Agostinho; et al. "Exploring quercetin's potential to counteract intestinal pro-inflammatory effects induced by silver nanoparticles". (2024): https://doi.org/10.48797/sl.2024.240.
    https://doi.org/10.48797/sl.2024.240
  13. Ramalho, Ana; Carvalho, Félix; Fernandes, Eduarda; Freitas, Marisa. "Unveiling the impact of parabens on human neutrophils oxidative burst under hyperglycaemia conditions". (2024): https://doi.org/10.48797/sl.2024.197.
    https://doi.org/10.48797/sl.2024.197
  14. Carapito, Ângela; Teixeira-Marques, Ana; Jerónimo, Carmen; Henrique, Rui; A. Roque, Ana Cecília; Carvalho, Félix; Pinto, Joana; Guedes de Pinho, Paula. "Urinary volatile metabolomic biomarkers for detection of bladder cancer". (2024): https://doi.org/10.48797/sl.2024.130.
    https://doi.org/10.48797/sl.2024.130
  15. Sofia Reis Brandão; Ana Reis-Mendes; Maria João Neuparth; Félix Carvalho; Rita Ferreira; Vera Marisa Costa. "The Metabolic Fingerprint of Doxorubicin-Induced Cardiotoxicity in Male CD-1 Mice Fades Away with Time While Autophagy Increases". Pharmaceuticals (2023): https://doi.org/10.3390/ph16111613.
    10.3390/ph16111613
  16. Reis-Mendes, Ana; Ferreira, Mariana; Padrão, Ana Isabel; Duarte, José Alberto; Araújo, Ana Margarida; Remião, Fernando; Carvalho, Félix; et al. Corresponding author: Reis-Mendes, Ana. "The role of inflammation and antioxidant defenses in the cardiotoxicity of doxorubicin in elderly CD-1 male mice". Archives of Toxicology 97 12 (2023): 3163-3177. https://link.springer.com/article/10.1007/s00204-023-03586-1#citeas.
    Published • 10.1007/s00204-023-03586-1
  17. Rocha, Sílvia; Rufino, Ana T.; Freitas, Marisa; Silva, Artur M. S.; Carvalho, Félix; Fernandes, Eduarda. "Methodologies for Assessing Pancreatic Lipase Catalytic Activity: A Review". Critical Reviews in Analytical Chemistry (2023): 1-28. http://dx.doi.org/10.1080/10408347.2023.2221731.
    10.1080/10408347.2023.2221731
  18. Brandão, Sofia; Reis-Mendes, Ana; Duarte-Araújo, Margarida; Neuparth, Maria; Rocha, Hugo; Carvalho, Félix; Ferreira, Rita; et al. Corresponding author: Costa, Vera M. "Cardiac Molecular Remodeling by Anticancer Drugs: Doxorubicin Affects More Metabolism While Mitoxantrone Impacts More Autophagy in Adult CD-1 Male Mice". Biomolecules 13 6 (2023): 921. http://dx.doi.org/10.3390/biom13060921.
    10.3390/biom13060921
  19. Costa, Vera M; Capela, João Paulo; Bastos, Maria Lourdes; Remião, Fernando; Varner, Kurt James; Duarte, José Alberto; Carvalho, Félix; et al. Corresponding author: Carvalho, Félix. "Study of the potential toxicity of adrenaline to neurons, using the SH-SY5Y human cellular model". Brazilian Journal of Pharmaceutical Sciences 59 (2023): e20467. http://dx.doi.org/10.1590/s2175-97902023e20467.
    Published • 10.1590/s2175-97902023e20467
  20. Sandra I. Marques; Helena Carmo; Félix Carvalho; Susana I. Sá; João Pedro Silva. "A Semi-Automatic Method for the Quantification of Astrocyte Number and Branching in Bulk Immunohistochemistry Images". International Journal of Molecular Sciences (2023): https://doi.org/10.3390/ijms24054508.
    10.3390/ijms24054508
  21. Roque-Bravo, Rita; Silva, Rafaela Sofia; Malheiro, Rui F.; Carmo, Helena; Carvalho, Félix; da Silva, Diana Dias; Silva, João Pedro; et al. "Synthetic Cannabinoids: A Pharmacological and Toxicological Overview". Annual Review of Pharmacology and Toxicology 63 1 (2023): 187-209. http://dx.doi.org/10.1146/annurev-pharmtox-031122-113758.
    10.1146/annurev-pharmtox-031122-113758
  22. Ana Reis-Mendes; Félix Carvalho; Fernando Remião; Emília Sousa; Maria de Lourdes Bastos; Vera Marisa Costa. "Autophagy (but not metabolism) is a key event in mitoxantrone-induced cytotoxicity in differentiated AC16 cardiac cells". Archives of Toxicology (2023): https://doi.org/10.1007/s00204-022-03363-6.
    10.1007/s00204-022-03363-6
  23. Martins, Alexandra; da Silva, Diana Dias; Silva, Renata; Carvalho, Félix; Guilhermino, Lúcia. "Warmer water, high light intensity, lithium and microplastics: Dangerous environmental combinations to zooplankton and Global Health?". Science of The Total Environment 854 (2023): 158649. http://dx.doi.org/10.1016/j.scitotenv.2022.158649.
    10.1016/j.scitotenv.2022.158649
  24. Malheiro, Rui Filipe; Carmo, Helena; Carvalho, Félix; Silva, João Pedro; Malheiro, RF; Carmo, H; Carvalho, F; Silva, JP. "Cannabinoid-mediated targeting of mitochondria on the modulation of mitochondrial function and dynamics". Pharmacological Research 187 (2023): 106603. http://dx.doi.org/10.1016/j.phrs.2022.106603.
    Published • 10.1016/j.phrs.2022.106603
  25. Reis-Mendes, A.; Ferreira, M.; Padrão, A.I.; Duarte, J.A.; Duarte-Araújo, M.; Remião, F.; Carvalho, F.; et al. Corresponding author: Costa, Vera M. "The Role of Nrf2 and Inflammation on the Dissimilar Cardiotoxicity of Doxorubicin in Two-Time Points: a Cardio-Oncology In Vivo Study Through Time". Inflammation (2023): http://www.scopus.com/inward/record.url?eid=2-s2.0-85174019285&partnerID=MN8TOARS.
    Accepted • 10.1007/s10753-023-01908-0
  26. Sousa, A.; Rufino, A.T.; Fernandes, R.; Malheiro, A.; Carvalho, F.; Fernandes, E.; Freitas, M.. "Silver nanoparticles exert toxic effects in human monocytes and macrophages associated with the disruption of ¿¿m and release of pro-inflammatory cytokines". Archives of Toxicology 97 2 (2023): 405-420. http://www.scopus.com/inward/record.url?eid=2-s2.0-85142511559&partnerID=MN8TOARS.
    10.1007/s00204-022-03415-x
  27. Moberg, M.E.; Hamilton, E.B.; Zeng, S.M.; Bryazka, D.; Zhao, J.T.; Feldman, R.; Abate, Y.H.; et al. "Global, regional, and national mortality due to unintentional carbon monoxide poisoning, 2000–2021: results from the Global Burden of Disease Study 2021". The Lancet Public Health 8 11 (2023): e839-e849. http://www.scopus.com/inward/record.url?eid=2-s2.0-85174744964&partnerID=MN8TOARS.
    10.1016/S2468-2667(23)00185-8
  28. Dias-Carvalho, A.; Sá, S.I.; Carvalho, F.; Fernandes, E.; Costa, V.M.. "Inflammation as common link to progressive neurological diseases". Archives of Toxicology (2023): http://www.scopus.com/inward/record.url?eid=2-s2.0-85176455974&partnerID=MN8TOARS.
    10.1007/s00204-023-03628-8
  29. Sousa, A.; Azevedo, R.; Costa, V.M.; Oliveira, S.; Preguiça, I.; Viana, S.; Reis, F.; et al. "Biodistribution and intestinal inflammatory response following voluntary oral intake of silver nanoparticles by C57BL/6J mice". Archives of Toxicology 97 10 (2023): 2643-2657. http://www.scopus.com/inward/record.url?eid=2-s2.0-85168342548&partnerID=MN8TOARS.
    10.1007/s00204-023-03558-5
  30. Silva, J.P.; Carvalho, F.. "Drugs of abuse and epigenetics: Past, present and future,Drogas de abuso y epigenética: Pasado, presente y futuro". Adicciones 35 3 (2023): 219-226. http://www.scopus.com/inward/record.url?eid=2-s2.0-85174016985&partnerID=MN8TOARS.
    10.20882/adicciones.2006
  31. Dias-Carvalho, Ana; Margarida-Araújo, Ana; Reis-Mendes, Ana; Sequeira, Catarina Oliveira; Pereira, Sofia Azeredo; Guedes de Pinho, Paula; Carvalho, Félix; et al. Corresponding author: Costa, Vera M. "A Clinically Relevant Dosage of Mitoxantrone Disrupts the Glutathione and Lipid Metabolic Pathways of the CD-1 Mice Brain". International Journal of Molecular Sciences 24 17 (2023): 13126. http://hdl.handle.net/10362/158255.
    Published • https://doi.org/10.3390/ijms241713126
  32. Dinis-Oliveira, Ricardo Jorge; de Pinho, Paula Guedes; Santos, Liliana; Teixeira, Helena; Magalhães, Teresa; Santos, Agostinho; de Lourdes Bastos, Maria; et al. "Postmortem analyses unveil the poor efficacy of decontamination, anti-inflammatory and immunosuppressive therapies in Paraquat human intoxications". PLoS ONE 4 9 (2023): http://hdl.handle.net/10400.26/43768.
    https://doi.org/10.1371/journal.pone.0007149
  33. Daniel José Barbosa; João Paulo Capela; Luísa Maria Ferreira; Paula Sério Branco; Eduarda Fernandes; Maria de Lourdes Bastos; Félix Carvalho. "Ecstasy metabolites and monoamine neurotransmitters upshift the Na+/K+ ATPase activity in mouse brain synaptosomes". Archives of Toxicology (2022): https://doi.org/10.1007/s00204-022-03370-7.
    10.1007/s00204-022-03370-7
  34. Remião, Fernando; Carmo, Helena; Gomes, Miguel; Silva, Renata; Costa, Vera Marisa; Carvalho, Félix; Bastos, Maria de Lourdes; et al. "The impact of video lecture capture on student attainment and achievement of intended learning outcomes". Pharmacy Education 22 1 (2022): 843-855. http://dx.doi.org/10.46542/pe.2022.221.843855.
    10.46542/pe.2022.221.843855
  35. Martins, Alexandra; da Silva, Diana Dias; Silva, Renata; Carvalho, Félix; Guilhermino, Lúcia. "Long-term effects of lithium and lithium-microplastic mixtures on the model species Daphnia magna: Toxicological interactions and implications to "One Health"". Science of The Total Environment 838 (2022): 155934. http://dx.doi.org/10.1016/j.scitotenv.2022.155934.
    10.1016/j.scitotenv.2022.155934
  36. Brandão, Sofia Reis; Carvalho, Félix; Amado, Francisco; Ferreira, Rita; Costa, Vera M. Corresponding author: Costa, Vera M. "Insights on the molecular targets of cardiotoxicity induced by anticancer drugs: A systematic review based on proteomic findings". Metabolism 134 (2022): 155250. http://dx.doi.org/10.1016/j.metabol.2022.155250.
    Published • 10.1016/j.metabol.2022.155250
  37. Silva, João Pedro; Carvalho, Félix. "Therapeutical use of cannabis and cannabinoids: is there any scientific evidence? (INVITED, CORRESPONDING/SENIOR AUTHOR). To be published in March 2022.". Revista Española de Drogodependencias (2022):
    Submitted
  38. Silva, João Pedro; Carmo, Helena; Carvalho, Félix. "Drugs of abuse and kidney toxicity (INVITED, CORRESPONDING/SENIOR AUTHOR).". Current Opinion in Toxicology (invite-only) 32 (2022): 100360.
    Published • 10.1016/j.cotox.2022.100360
  39. Dionísio, Flávio; Araújo, Ana Margarida; Duarte-Araújo, Margarida; Bastos, Maria de Lourdes; Guedes de Pinho, Paula; Carvalho, Félix; Costa, Vera Marisa. Corresponding author: Costa, Vera Marisa. "Cardiotoxicity of cyclophosphamide¿s metabolites: an in vitro metabolomics approach in AC16 human cardiomyocytes". Archives of Toxicology 96 2 (2022): 653-671. http://dx.doi.org/10.1007/s00204-021-03204-y.
    10.1007/s00204-021-03204-y
  40. Frostad, J.J.; Nguyen, Q.P.; Baumann, M.M.; Blacker, B.F.; Marczak, L.B.; Deshpande, A.; Wiens, K.E.; et al. "Mapping development and health effects of cooking with solid fuels in low-income and middle-income countries, 2000–18: a geospatial modelling study". The Lancet Global Health 10 10 (2022): e1395-e1411. http://www.scopus.com/inward/record.url?eid=2-s2.0-85137821908&partnerID=MN8TOARS.
    10.1016/S2214-109X(22)00332-1
  41. Castelpietra, G.; Knudsen, A.K.S.; Agardh, E.E.; Armocida, B.; Beghi, M.; Iburg, K.M.; Logroscino, G.; et al. "The burden of mental disorders, substance use disorders and self-harm among young people in Europe, 1990–2019: Findings from the Global Burden of Disease Study 2019". The Lancet Regional Health - Europe 16 (2022): http://www.scopus.com/inward/record.url?eid=2-s2.0-85126962943&partnerID=MN8TOARS.
    10.1016/j.lanepe.2022.100341
  42. Silva, J.P.; Carvalho, F.. "The therapeutic use of cannabis and cannabinoids,El uso terapéutico del cannabis y los cannabinoides". Revista Espanola de Drogodependencias 47 4 (2022): 103-122. http://www.scopus.com/inward/record.url?eid=2-s2.0-85147675421&partnerID=MN8TOARS.
    10.54108/10031
  43. Burkart, K.; Causey, K.; Cohen, A.J.; Wozniak, S.S.; Salvi, D.D.; Abbafati, C.; Adekanmbi, V.; et al. "Estimates, trends, and drivers of the global burden of type 2 diabetes attributable to PM2·5 air pollution, 1990–2019: an analysis of data from the Global Burden of Disease Study 2019". The Lancet Planetary Health 6 7 (2022): e586-e600. http://www.scopus.com/inward/record.url?eid=2-s2.0-85134425745&partnerID=MN8TOARS.
    10.1016/S2542-5196(22)00122-X
  44. Dias-Carvalho, A.; Ferreira, M.; Reis-Mendes, A.; Ferreira, R.; Bastos, M.L.; Fernandes, E.; Sá, S.I.; et al. "Chemobrain: mitoxantrone-induced oxidative stress, apoptotic and autophagic neuronal death in adult CD-1 mice". Archives of Toxicology 96 6 (2022): 1767-1782. http://www.scopus.com/inward/record.url?eid=2-s2.0-85126818986&partnerID=MN8TOARS.
    Accepted • 10.1007/s00204-022-03261-x
  45. Roberts, N.L.S.; Johnson, E.K.; Zeng, S.M.; Hamilton, E.B.; Abdoli, A.; Alahdab, F.; Alipour, V.; et al. "Global mortality of snakebite envenoming between 1990 and 2019". Nature Communications 13 1 (2022): http://www.scopus.com/inward/record.url?eid=2-s2.0-85140789483&partnerID=MN8TOARS.
    10.1038/s41467-022-33627-9
  46. Haakenstad, A.; Irvine, C.M.S.; Knight, M.; Bintz, C.; Aravkin, A.Y.; Zheng, P.; Gupta, V.; et al. "Measuring the availability of human resources for health and its relationship to universal health coverage for 204 countries and territories from 1990 to 2019: a systematic analysis for the Global Burden of Disease Study 2019". The Lancet 399 10341 (2022): 2129-2154. http://www.scopus.com/inward/record.url?eid=2-s2.0-85131397944&partnerID=MN8TOARS.
    10.1016/S0140-6736(22)00532-3
  47. Garcia, J.; Carvalho, A.; das Neves, R.P.; Malheiro, R.; Rodrigues, D.F.; Figueiredo, P.R.; Bovolini, A.; et al. "Antidotal effect of cyclosporine A against a-amanitin toxicity in CD-1 mice, at clinical relevant doses". Food and Chemical Toxicology 166 (2022): http://www.scopus.com/inward/record.url?eid=2-s2.0-85132231769&partnerID=MN8TOARS.
    10.1016/j.fct.2022.113198
  48. Ledesma, J.R.; Ma, J.; Vongpradith, A.; Maddison, E.R.; Novotney, A.; Biehl, M.H.; Legrand, K.E.; et al. "Global, regional, and national sex differences in the global burden of tuberculosis by HIV status, 1990–2019: results from the Global Burden of Disease Study 2019". The Lancet Infectious Diseases 22 2 (2022): 222-241. http://www.scopus.com/inward/record.url?eid=2-s2.0-85123879325&partnerID=MN8TOARS.
    10.1016/S1473-3099(21)00449-7
  49. Capela, J.P.; Carvalho, F.D.. "A review on the mitochondrial toxicity of “ecstasy” (3,4-methylenedioxymethamphetamine, MDMA)". Current Research in Toxicology 3 (2022): http://www.scopus.com/inward/record.url?eid=2-s2.0-85131041414&partnerID=MN8TOARS.
    10.1016/j.crtox.2022.100075
  50. Reiner, R.C.; Welgan, C.A.; Troeger, C.E.; Baumann, M.M.; Weiss, D.J.; Deshpande, A.; Blacker, B.F.; et al. "The overlapping burden of the three leading causes of disability and death in sub-Saharan African children". Nature Communications 13 1 (2022): http://www.scopus.com/inward/record.url?eid=2-s2.0-85143491451&partnerID=MN8TOARS.
    10.1038/s41467-022-34240-6
  51. Tyrovolas, S.; Stergachis, A.; Krish, V.S.; Chang, A.Y.; Skirbekk, V.; Dieleman, J.L.; Chatterji, S.; et al. "Global, regional, and national burden of diseases and injuries for adults 70 years and older: Systematic analysis for the Global Burden of Disease 2019 Study". BMJ 376 (2022): http://www.scopus.com/inward/record.url?eid=2-s2.0-85127409980&partnerID=MN8TOARS.
    10.1136/bmj-2021-068208
  52. Haeuser, E.; Serfes, A.L.; Cork, M.A.; Yang, M.; Abbastabar, H.; Abhilash, E.S.; Adabi, M.; et al. "Mapping age- and sex-specific HIV prevalence in adults in sub-Saharan Africa, 2000–2018". BMC Medicine 20 1 (2022): http://www.scopus.com/inward/record.url?eid=2-s2.0-85144401013&partnerID=MN8TOARS.
    10.1186/s12916-022-02639-z
  53. Nichols, E.; Steinmetz, J.D.; Vollset, S.E.; Fukutaki, K.; Chalek, J.; Abd-Allah, F.; Abdoli, A.; et al. "Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050: an analysis for the Global Burden of Disease Study 2019". The Lancet Public Health 7 2 (2022): e105-e125. http://www.scopus.com/inward/record.url?eid=2-s2.0-85123842750&partnerID=MN8TOARS.
    10.1016/S2468-2667(21)00249-8
  54. Schmidt, C.A.; Cromwell, E.A.; Hill, E.; Donkers, K.M.; Schipp, M.F.; Johnson, K.B.; Pigott, D.M.; et al. "The prevalence of onchocerciasis in Africa and Yemen, 2000–2018: a geospatial analysis". BMC Medicine 20 1 (2022): http://www.scopus.com/inward/record.url?eid=2-s2.0-85137312681&partnerID=MN8TOARS.
    10.1186/s12916-022-02486-y
  55. Reis Brandão, Sofia; Reis-Mendes, Ana; Duarte-Araújo, Margarida; Neuparth, Maria João; Carvalho, Félix; Ferreira, Rita; Costa, Vera Marisa. "Molecular alterations underlying Doxorubicin’s Chronic Cardiotoxicity in a mouse model". (2022): https://doi.org/10.51126/revsalus.v4iSup.250.
    https://doi.org/10.51126/revsalus.v4iSup.250
  56. Lobato-Freitas, Carolina; Carmo, Helena; Carvalho, Félix; Silva, João Pedro; Dias da Silva, Diana. "AMB-Fubinaca, AB-Chminaca and HU-308’s effects on in vitro differentiation and proliferation of NG108-15 cells". (2022): https://doi.org/10.51126/revsalus.v4iSup.369.
    https://doi.org/10.51126/revsalus.v4iSup.369
  57. Sharma, Rajesh; Abbasi-kangevari, Mohsen; Abd-rabu, Rami; Abidi, Hassan; Abu-Gharbieh, Eman; Acuna, Juan Manuel; Adhikari, Sangeet; et al. "Global, regional, and national burden of colorectal cancer and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019". The Lancet Gastroenterology and Hepatology 7 7 (2022): 627-647. http://hdl.handle.net/10362/136124.
    https://doi.org/10.1016/S2468-1253(22)00044-9
  58. Pereira Teixeira, Catarina; Garcia, Maria Rita; Bravo, Rita Roque; Carmo, Helena; Carvalho, Félix; Silva, João Pedro; Dias da Silva, Diana. "Synthetic cannabinoids affect the expression of autophagic mediators ATG5, BECLIN-1, RAB7A and LC3 in brain-derived NG108-15 cells". (2022): https://doi.org/10.51126/revsalus.v4iSup.371.
    https://doi.org/10.51126/revsalus.v4iSup.371
  59. Pinheiro, Sara; Carvalho, Félix; Carmo, Helena. "Nitrites: one “click” to suicide". (2022): https://doi.org/10.51126/revsalus.v4iSup.384.
    https://doi.org/10.51126/revsalus.v4iSup.384
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  228. J. Alexandre; H. Carmo; F. Carvalho; J.P. Silva. "Synthetic cannabinoids enhance neuronal differentiation in neuroblastoma cells at in vivo relevant concentrations". Toxicology Letters (2018): https://publons.com/publon/15042511/.
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  229. P. Guedes de Pinho; D. Sousa; F. Carvalho; H. Carmo; M.D.L. Bastos; D. Dias da Silva. "2,4-Dinitrophenol (2,4-DNP) induces toxicity in primary hepatocytes through oxidative stress and mitochondrial dysregulation". Toxicology Letters (2018): https://publons.com/publon/15426465/.
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  230. R.R.D.S. Bravo; P. Moreira; F. Carvalho; M.D.L. Bastos; H. Carmo; D. Dias da Silva. "The synthetic psychostimulant 4-fluoromethamphetamine induces in vitro hepatotoxic effects, via CYP2E1 metabolism". Toxicology Letters (2018): https://publons.com/publon/15426463/.
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  231. Félix Carvalho; Bastos, M. D. L.; Silva, S. O.; Carmo, H.; Silva, D. D. D.. "Benzylpiperazine (BZP) additively increases Methylenedioxymethamphetamine (MDMA) cardiotoxicity in H9c2 cells, an effect potentiatted by hyperthermia". Toxicology Letters (2018): https://publons.com/publon/21429739/.
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  232. J. Parra; A.R.T.S. Araujo; F. Carvalho; H. Carmo; J.P. Silva. "Neurotoxicity assessment of four synthetic cathinones in neuroblastoma cells at in vivo relevant concentrations". Toxicology Letters (2018): https://publons.com/publon/15042512/.
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  233. Bruno M Fonseca; Marta Almada; Márcia Santos; Helena Gaspar; Felix Carvalho; Natercia Teixeira; Georgina Correia-da-Silva. "Prooxidant effects of synthetic cannabinoids on endometrial cells, results in a strenous rebound adaptative effect". Free Radical Biology and Medicine (2018): https://publons.com/publon/14350769/.
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  234. Tânia Soares; Marisa Freitas; Félix Carvalho; Eduarda Fernandes. "Silver nanoparticles stimulate neutrophils oxidative burst through the activation of protein kinase C". Free Radical Biology and Medicine (2018): https://publons.com/publon/14717603/.
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  235. Roth, G.A.; Abate, D.; Abate, K.H.; Abay, S.M.; Abbafati, C.; Abbasi, N.; Abbastabar, H.; et al. "Erratum: Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980–2017: a systematic analysis for the Global Burden of Disease Study 2017 (The Lancet (2018) 392(10159) (1736–1788)(S0140673618322037)(10.1016/S0140-6736(18)32203-7))". The Lancet 392 10160 (2018): 2170-2170. http://www.scopus.com/inward/record.url?eid=2-s2.0-85057157683&partnerID=MN8TOARS.
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  236. J. Soares; V. Costa; S. Bronze; H. Gaspar; S. Santos; M.D.L. Bastos; F. Carvalho; João Paulo Capela. "Clorgyline and N-acetyl-L-cysteine provide partial protection against the toxicity of synthetic cathinones and methamphetamine on SH-SY5Y humans cells". Toxicology Letters (2018): https://publons.com/publon/19926013/.
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  237. M.J. Martins; R.R.D.S. Bravo; H. Carmo; F. Carvalho; M.D.L. Bastos; R.J. Dinis-Oliveira; D. Dias da Silva. "Co-exposure to cocaine and ethanol induces oxidative impairment in H9c2 cardiomyocytes". Toxicology Letters (2018): https://publons.com/publon/15426462/.
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  238. S.P. Camões; A. de la Fuente; F. Carvalho; M. Abal; J.M. Santos; J.P. Miranda. "Treatment of impaired wounds - Understanding the therapeutic mechanisms of umbilical cord-derived mesenchymal stem cells". Toxicology Letters (2018): https://publons.com/publon/17759143/.
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  239. Soares, T.; M. Gónzalez-Gómez; Gonzalez-Gomez, M.; Rivas, J.; Félix Carvalho; Freitas, P.; Carvalho, F.; Fernandes, E.. "Polyethylemine coated silver nanoparticles induce human neutrophils' oxidative burst via NADPH oxidase, through the activation of PKC". Toxicology Letters (2018): https://publons.com/publon/21429740/.
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  240. João P. Silva; Helena Carmo; Felix Carvalho. "The synthetic cannabinoid XLR-11 induces in vitro nephrotoxicity by impairment of endocannabinoid-mediated regulation of mitochondrial function homeostasis and triggering of apoptosis". (2018): https://hdl.handle.net/10216/110755.
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  241. Maria João Valente; Cristina Amaral; Georgina Correia-da-Silva; José Alberto Duarte; Maria de Lourdes Bastos; Félix Carvalho; Paula Guedes de Pinho; Márcia Carvalho. "Methylone and MDPV activate autophagy in human dopaminergic SH-SY5Y cells: a new insight into the context of ß-keto amphetamines-related neurotoxicity". Archives of Toxicology (2017): https://doi.org/10.1007/s00204-017-1984-z.
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  242. Fernando Remião; A. Rita Lima; Daniela Rodrigues; Alfredo G. Casanova; Helena Carmo; Félix Carvalho; Maria Lourdes Bastos. "TOX-OER MOOC: The pharmaco and toxicokinetics module". Toxicology Letters 280 (2017): S305-S305. https://doi.org/10.1016%2Fj.toxlet.2017.07.850.
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  243. Ana Santos-Carvalho; Adriana Fontes; Nuno Santos; Ana Margarida Araújo; Paula Guedes de Pinho; Claudia Cavadas; Félix Carvalho; Sónia Ferreira. "Unravelling the mechanisms of neuronal, hepatic, cardiac and renal cell toxicity of two synthetic cannabinoids, 5F-PB 22 and XLR-11". Toxicology Letters 280 (2017): S87-S87. https://doi.org/10.1016%2Fj.toxlet.2017.07.239.
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  244. João Pedro Silva; Helena Carmo; Félix Carvalho. "In vitro nephrotoxicity of synthetic cannabinoids". Toxicology Letters 280 (2017): S137-S137. https://doi.org/10.1016%2Fj.toxlet.2017.07.384.
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  245. Maria João Valente; Cristina Amaral; Georgina Correia-da-Silva; José Alberto Duarte; Maria de Lourdes Bastos; Félix Carvalho; Paula Guedes de Pinho; Márcia Carvalho. "Role of autophagy, apoptosis and oxidative stress in the toxicity of ß-keto amphetamines to human dopaminergic SH-SY5Y cells". Toxicology Letters 280 (2017): S152-S152. https://doi.org/10.1016%2Fj.toxlet.2017.07.425.
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  246. Ana Margarida Araújo; Ana Rita Lima; Maria de Lourdes Bastos; Félix Carvalho; Márcia Carvalho; Paula Guedes de Pinho. "Effect of subtoxic and toxic concentrations of galactosamine in the metabolome of primary mouse hepatocytes". Toxicology Letters 280 (2017): S295-S295. https://doi.org/10.1016%2Fj.toxlet.2017.07.828.
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  247. Emanuele Amorim Alves; Pedro Brandão; João Filipe Neves; Sara Manuela Cravo; José Xavier Soares; Jean-Paul C. Grund; José Alberto Duarte; et al. "Repeated subcutaneous administrations of krokodil causes skin necrosis and internal organs toxicity in Wistar rats: putative human implications". Human Psychopharmacology: Clinical and Experimental 32 3 (2017): e2572-e2572. https://doi.org/10.1002%2Fhup.2572.
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  248. Fonseca, D. A.; Guerra, A. F.; Carvalho, F.; Fernandes, E.; Ferreira, L. M.; Branco, P. S.; Antunes, P. E.; Antunes, M. J.; Cotrim, M. D.. "Hyperthermia Severely Affects the Vascular Effects of MDMA and Metabolites in the Human Internal Mammary Artery In Vitro". Cardiovascular Toxicology 17 4 (2017): 405-416. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000411104600004&KeyUID=WOS:000411104600004.
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  251. Feio-Azevedo, R.; Costa, V. M.; Ferreira, L. M.; Branco, P. S.; Pereira, F. C.; Bastos, M. L.; Carvalho, E.; Capela, J. P.. "Toxicity of the amphetamine metabolites 4-hydroxyamphetamine and 4-hydroxynorephedrine in human dopaminergic differentiated SH-SY5Y cells". Toxicology Letters 269 (2017): 65-76. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000397369700008&KeyUID=WOS:000397369700008.
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  253. Araújo, A.M.; Carvalho, M.; Carvalho, F.; Bastos, M.D.L.; Guedes de Pinho, P.. "Metabolomic approaches in the discovery of potential urinary biomarkers of drug-induced liver injury (DILI)". Critical Reviews in Toxicology 47 8 (2017): 633-649. http://www.scopus.com/inward/record.url?eid=2-s2.0-85029228329&partnerID=MN8TOARS.
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  254. Barbosa, J.; Faria, J.; Leal, S.; Afonso, L.P.; Lobo, J.; Queirós, O.; Moreira, R.; Carvalho, F.; Dinis-Oliveira, R.J.. "Acute administration of tramadol and tapentadol at effective analgesic and maximum tolerated doses causes hepato- and nephrotoxic effects in Wistar rats". Toxicology 389 (2017): 118-129. http://www.scopus.com/inward/record.url?eid=2-s2.0-85021952522&partnerID=MN8TOARS.
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  257. Gameiro, M.; Silva, R.; Rocha-Pereira, C.; Carmo, H.; Carvalho, F.; Bastos, M.D.L.; Remião, F.. "Cellular models and in vitro assays for the screening of modulators of P-gp, MRP1 and BCRP". Molecules 22 4 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85019668905&partnerID=MN8TOARS.
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  258. Rodrigues, D.; Freitas, M.; Marisa Costa, V.; Arturo Lopez-Quintela, M.; Rivas, J.; Freitas, P.; Carvalho, F.; Fernandes, E.; Silva, P.. "Quantitative histochemistry for macrophage biodistribution on mice liver and spleen after the administration of a pharmacological-relevant dose of polyacrylic acid-coated iron oxide nanoparticles". Nanotoxicology 11 2 (2017): 256-266. http://www.scopus.com/inward/record.url?eid=2-s2.0-85013656428&partnerID=MN8TOARS.
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  259. Alves, E.A.; Brandao, P.; Magalhaes, T.; Carvalho, F.; Dinis-Oliveira, R.J.. "Fatal Intoxications in the North of Portugal: 12 Years of Retrospective Analysis". Current drug safety 12 1 (2017): 39-45. http://www.scopus.com/inward/record.url?eid=2-s2.0-85045926287&partnerID=MN8TOARS.
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  260. Alves, E.A.; Agonia, A.S.; Cravo, S.M.; Afonso, C.M.; Netto, A.D.P.; de Lourdes Bastos, M.; Carvalho, F.; Dinis-Oliveira, R.J.. "GC-MS method for the analysis of thirteen opioids, cocaine and cocaethylene in whole blood based on a modified quechers extraction". Current Pharmaceutical Analysis 13 3 (2017): 215-223. http://www.scopus.com/inward/record.url?eid=2-s2.0-85019686660&partnerID=MN8TOARS.
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  262. Reis-Mendes, A.; Gomes, A.S.; Carvalho, R.A.; Carvalho, F.; Remião, F.; Pinto, M.; Bastos, M.L.; Sousa, E.; Costa, V.M.. "Naphthoquinoxaline metabolite of mitoxantrone is less cardiotoxic than the parent compound and it can be a more cardiosafe drug in anticancer therapy". Archives of Toxicology 91 4 (2017): 1871-1890. http://www.scopus.com/inward/record.url?eid=2-s2.0-84987667526&partnerID=MN8TOARS.
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  263. Dias da Silva, D.; Silva, M.J.; Moreira, P.; Martins, M.J.; Valente, M.J.; Carvalho, F.; Bastos, M.L.; Carmo, H.. "In vitro hepatotoxicity of ‘Legal X’: the combination of 1-benzylpiperazine (BZP) and 1-(m-trifluoromethylphenyl)piperazine (TFMPP) triggers oxidative stress, mitochondrial impairment and apoptosis". Archives of Toxicology 91 3 (2017): 1413-1430. http://www.scopus.com/inward/record.url?eid=2-s2.0-84976428177&partnerID=MN8TOARS.
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  264. Alexander Vardavas; Manolis Tzatzarakis; Polychronis Stivaktakis; Persefoni Fragkiadaki; Athanasios Alegakis; John Tsiaoussis; Christina Tsitsimpikou; Félix Carvalho; Aristidis Tsatsakis. "Aldehyde oxidase metabolism route inhibition via sodium tungstate in imidacloprid exposed rabbits". Toxicology Letters (2017): https://publons.com/publon/5034255/.
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  266. Félix Carvalho. "Preliminary Neurological Findings from a Prospective Cohort of Children Exposed to Zika Virus During Pregnancy". Annals of Neurology (2017): https://publons.com/publon/14717604/.
  267. Moreira, P.; Cunha, S.; Dias Da Silva, D.; Carvalho, F.; Bastos, M.; Carmo, H.. "Development and validation of a method for the simultaneous quantification of two piperazines used as drugs of abuse". Toxicology Letters 258 (2016): S296-S296. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000402436700890&KeyUID=WOS:000402436700890.
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  270. Baltazar, M. T.; Dinis-Oliveira, R. J.; Guilhermino, L.; Duarte, J. A.; Bastos, M. L.; Carvalho, F.. "Improving the human and environmental safety of paraquat". Toxicology Letters 259 (2016): S29-S29. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000396848100073&KeyUID=WOS:000396848100073.
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  637. Carvalho, F.; Fernandes, E.; Remião, F.; Gomes-Da-Silva, J.; Tavares, M.A.; Bastos, M.D.L.. "Adaptative response of antioxidant enzymes in different areas of rat brain after repeated d-amphetamine administration". Addiction Biology 6 3 (2001): 213-221. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034927677&partnerID=MN8TOARS.
    10.1080/13556210120056544
  638. Valentão, P.; Fernandas, E.; Carvalho, F.; Andrade, P.B.; Seabra, R.M.; Bastos, M.L.. "Antioxidant activity of Centaurium erythraea infusion evidenced by its superoxide radical scavenging and xanthine oxidase inhibitory activity". Journal of Agricultural and Food Chemistry 49 7 (2001): 3476-3479. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034839984&partnerID=MN8TOARS.
    10.1021/jf001145s
  639. Remião, F.; Carmo, H.; Carvalho, F.; Bastos, M.L.. "The study of oxidative stress in freshly isolated Ca2+-tolerant cardiomyocytes from the adult rat". Toxicology in Vitro 15 4-5 (2001): 283-287. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034830263&partnerID=MN8TOARS.
    10.1016/S0887-2333(01)00022-4
  640. Carvalho, M.; Carvalho, F.; Bastos, M.L.. "Is hyperthermia the triggering factor for hepatotoxicity induced by 3,4-methylenedioxymethamphetamine (ecstasy)? An in vitro study using freshly isolated mouse hepatocytes". Archives of Toxicology 74 12 (2001): 789-793. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034466546&partnerID=MN8TOARS.
    10.1007/s002040000200
  641. Lemos-Amado, F.; Domingues, P.; Ferrer-Correia, A.; Remião, F.; Milhazes, N.; Borges, F.; Carvalho, F.D.; Bastos, M.L.. "Electrospray tandem mass spectrometry of aminochromes". Rapid Communications in Mass Spectrometry 15 24 (2001): 2466-2471. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035543079&partnerID=MN8TOARS.
    10.1002/rcm.498
  642. Carvalho, F.; Duarte, J.; Neuparth, M.; Carmo, H.; Fernandes, E.; Remião, F.; Bastos, M.. "Hydrogen peroxide production in mouse tissues after acute d-amphetamine administration. Influence of monoamine oxidase inhibition". Archives of Toxicology 75 8 (2001): 465-469. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034758492&partnerID=MN8TOARS.
    10.1007/s002040100264
  643. Remião F; Carmo H; Carvalho F; Bastos ML; Remio, F.; Carmo, H.; Carvalho, F.; et al. "Simultaneous determination of reduced and oxidized glutathione in freshly isolated rat hepatocytes and cardiomyocytes by HPLC with electrochemical detection.". Biomedical chromatography : BMC 14 7 (2000): 468-473. http://europepmc.org/abstract/med/11113926.
    10.1002/1099-0801(200011)14:7<468::aid-bmc10>3.0.co;2-c
  644. Remião F; Carmo H; Carvalho FD; Bastos ML; Remiäo, F.; Carmo, H.; Carvalho, F.D.; et al. "Inhibition of glutathione reductase by isoproterenol oxidation products.". Journal of enzyme inhibition 15 1 (2000): 47-61. http://europepmc.org/abstract/med/10850954.
    10.1080/14756369909030340
  645. Carvalho, F; Fernandes, E; Remiao, F; Gomes-da-Silva, J; Tavares, MA; Bastos, ML. "Effect of repeated exposure to d-amphetamine on endogenous antioxidants in the rat brain". British Journal of Pharmacology 127 (1999): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000081651500066&KeyUID=WOS:000081651500066.
  646. Duarte, JA; Carvalho, F; Natsis, K; Remiao, F; Bastos, ML; Soares, JMC; Appell, HJ. "Structural alterations of skeletal muscle induced by chronic administration of d-amphetamine and food restriction". Basic and Applied Myology 9 2 (1999): 65-69. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000084455100004&KeyUID=WOS:000084455100004.
  647. Carvalho, F.; Fernandes, E.; Remião, F.; De Lourdes Bastos, M.. "Effect of d-amphetamine repeated administration on rat antioxidant defences". Archives of Toxicology 73 2 (1999): 83-89. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032940969&partnerID=MN8TOARS.
    10.1007/s002040050591
  648. Félix Carvalho; Eduarda Fernandes; Fernando Remiño; Paulo Sousa; Maria de Lourdes Bastos. "Adaptation of rat liver and kidney antioxidant defenses after d-Amphetamine repeated administration". Toxicology Letters 95 (1998): 55-55. https://doi.org/10.1016%2Fs0378-4274%2898%2980218-x.
    10.1016/s0378-4274(98)80218-x
  649. Appell, HJ; Duarte, JA; Gloser, S; Remiao, F; Carvalho, F; Bastos, ML; Soares, JMC; et al. "Administration of tourniquet .2. Prevention of postischemic oxidative stress can reduce muscle edema". Archives of Orthopaedic and Trauma Surgery 116 1-2 (1997): 101-105. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:A1997VZ64800022&KeyUID=WOS:A1997VZ64800022.
    10.1007/BF00434111
  650. Carvalho, F.; Remião, F.; Soares, M.E.; Catarino, R.; Queiroz, G.; Bastos, M.L.. "d-Amphetamine-induced hepatotoxicity: Possibie contribution of catecholamines and hyperthermia to the effect studied in isolated rat hepatocytes". Archives of Toxicology 71 7 (1997): 429-436. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030927810&partnerID=MN8TOARS.
    10.1007/s002040050407
  651. Carvalho, F.; Bastos, M.D.L.. "Estudo da hepatotoxidade da anfetamina ensaios in vitro". Revista Portuguesa de Farmacia 47 3 (1997): 111-120. http://www.scopus.com/inward/record.url?eid=2-s2.0-0347108065&partnerID=MN8TOARS.
  652. Duarte, J.A.; Glöser, S.; Remiäo, F.; Carvalho, F.; Bastos, M.L.; Soares, J.M.C.; Appell, H.-J.; et al. "Administration of tourniquet: I. Are edema and oxidative stress related to each other and to the duration of ischemia in reperfused skeletal muscle?". Archives of Orthopaedic and Trauma Surgery 116 1-2 (1997): 97-100. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031060012&partnerID=MN8TOARS.
    10.1007/BF00434110
  653. Cardoso, A.M.; Barros, C.M.F.; Ferrer Correia, A.J.; Cardoso, J.M.; Cortez, A.; Carvalho, F.; Baldaia, L.. "Identification of vertebrate type steroid hormones in the shrimp Penaeus Japonicus by tandem mass spectrometry and sequential product ion scanning". Journal of the American Society for Mass Spectrometry 8 4 (1997): 365-370. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031127306&partnerID=MN8TOARS.
    10.1016/S1044-0305(96)00282-6
  654. Bastos, M.L.; Carvalho, F.; Remião, F.; Mendes, M.E.; Ferreira, M.A.; Soares, M.E.; Timbrell, J.A.. "Changes in taurine levels in response to repeated administration of the ß2-agonist salbutamol in lambs". Journal of Veterinary Pharmacology and Therapeutics 20 1 (1997): 33-37. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031058218&partnerID=MN8TOARS.
    10.1046/J.1365-2885.1997.00046.X
  655. Carvalho, F.; Remião, F.; Amado, F.; Domingues, P.; Ferrer Correia, A.J.; Bastos, M.L.. "d-Amphetamine interaction with glutathione in freshly isolated rat hepatocytes". Chemical Research in Toxicology 9 6 (1996): 1031-1036. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029784568&partnerID=MN8TOARS.
    10.1021/tx9501750
  656. Carvalho, Félix; Remião, Fernando; Soares, M.Elisa; Catarino, Rita; Sousa, Paulo; Queiroz, Glória; Bastos, M.Lourdes; et al. "d-amphetamine and catecholamines potentiate hyperthermia-induced hepatotoxicity in isolated rat hepatoxytes". Toxicology Letters 88 168 (1996): 47-47. https://doi.org/10.1016%2Fs0378-4274%2896%2980167-6.
    Published • 10.1016/S0378-4274(96)80167-6
  657. Queiroz, G.; Gonçalves, J.; Carvalho, M.; Vale, P.; QUEIROZ, G; GONCALVES, J; CARVALHO, F; VALE, P. "Electrically-evoked release of taurine in the rat vas deferens: evidence for a purinoceptor-mediated effect". Naunyn-Schmiedeberg's Archives of Pharmacology 351 1 (1995): 60-66. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028872991&partnerID=MN8TOARS.
    10.1007/BF00169065
  658. Fernandes, E.R.; Carvalho, F.D.; Remiao, F.G.; Bastos, L.M.; Pinto, M.M.; Gottlieb, O.R.. "Hepatoprotective activity of xanthones and xanthonolignoids against tert-Butylhydroperoxide-Induced toxicity in isolated rat hepatocytes - Comparison with silybin". Pharmaceutical Research 12 11 (1995): 1756-1760. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029620247&partnerID=MN8TOARS.
    10.1023/A:1016230125496
  659. De Lurdes Bastos, M.; Carvalho, F.; Soares, M.E.; Remiao, F.; Ferreira, M.A.. "Biochemical markers responsible for drug toxicity | MARCADORES BIOQUIMICOS INDICIADORES DA TOXICIDADE DOS FARMACOS". Revista Portuguesa de Farmacia 45 1 (1995): 11-15. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028943291&partnerID=MN8TOARS.
  660. SOARES, ME; BASTOS, ML; CARVALHO, F; FERREIRA, M. "DETERMINATION OF AS, CD, AND PB IN FEEDSTUFF BY GRAPHITE-FURNACE AAS". Atomic Spectroscopy 16 4 (1995): 149-153. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:A1995RR98200004&KeyUID=WOS:A1995RR98200004.
  661. CARVALHO, F; BASTOS, ML; REMIAO, F; FERREIRA, MA; Carvalho F; Bastos ML; Remiao F; Ferreira MA. "DETERMINATION OF OXALATES IN CORK STOPPERS BY HPLC WITH ELECTROCHEMICAL DETECTION". American Journal of Enology and Viticulture 46 1 (1995): 63-66. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:A1995QN20600012&KeyUID=WOS:A1995QN20600012.
  662. Carvalho, F.; Waterfield, C.J.; De Lourdes Bastos, M.; Ferreira, M.; Timbrell, J.A.. "The effect of repeated administration of salbutamol on urinary and liver taurine levels in rats". Pharmacology Communications 5 3 (1995): 171-180. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028905093&partnerID=MN8TOARS.
  663. Carvalho, F.; Guilhermino, L.; Ribeiro, R.; Gonçalves, F.; Soares, A.M.V.M.. "METIER (modular ecotoxicity tests incorporating ecological relevance). II. Ecotoxicity of poorly water-soluble compounds: Concentration versus dose". Archives of Environmental Contamination and Toxicology 29 4 (1995): 431-434. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028981369&partnerID=MN8TOARS.
    10.1007/BF00208370
  664. Bastos ML; Carvalho F; Soares ME; Fernandes J; Ferreira M; Bastos, M L; Carvalho, F; et al. "Bioavailability of residues of diazepam and its metabolites.". Bollettino chimico farmaceutico 133 1 (1994): 27-31. http://europepmc.org/abstract/med/8166961.
  665. Carvalho, F.D.; Remiao, F.; Vale, P.; Timbrell, J.A.; Bastos, M.L.; Ferreira, M.A.; CARVALHO, FD; et al. "Glutathione and cysteine measurement in biological samples by HPLC with a glassy carbon working detector". Biomedical Chromatography 8 3 (1994): 134-136. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028284807&partnerID=MN8TOARS.
    10.1002/bmc.1130080308
  666. Duarte, J.A.; Carvalho, F.; Bastos, M.L.; Soared, J.M.C.; Appell, H.-J.. "Do invading leucocytes contribute to the decrease in glutathione concentrations indicating oxidative stress in exercised muscle, or are they important for its recovery?". European Journal of Applied Physiology and Occupational Physiology 68 1 (1994): 48-53. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028155954&partnerID=MN8TOARS.
    10.1007/BF00599241
  667. Carvalho, F.D.; Remiao, F.; Vale, P.; Timbrell, J.A.; Bastos, M.L.; Ferreira, M.A.. "Erratum: Glutathione and cysteine measurement in biological samples by HPLC with a glassy carbon work detector. (Biomedical Chromatography (1994) 8 (134))". Biomedical Chromatography 8 6 (1994): http://www.scopus.com/inward/record.url?eid=2-s2.0-0027998085&partnerID=MN8TOARS.
  668. Félix Dias Carvalho; Maria de Lurdes Bastos; John A. Timbrell; Dias Carvalho, F.; de Lurdes Bastos, M.; Timbrell, J.A.; CARVALHO, FD; BASTOS, MD; TIMBRELL, JA. "Depletion of total non-protein sulphydryl groups in mouse tissues after administration of d-amphetamine". Toxicology 83 1-3 (1993): 31-40. https://doi.org/10.1016%2F0300-483x%2893%2990089-b.
    10.1016/0300-483x(93)90089-b
  669. Duarte, J.A.R.; Appell, H.-J.; Carvalho, F.; Bastos, M.L.; Soares, J.M.; DUARTE, JAR; APPELL, HJ; et al. "Endothelium-derived oxidative stress may contribute to exercise-induced muscle damage". International Journal of Sports Medicine 14 8 (1993): 440-443. http://www.scopus.com/inward/record.url?eid=2-s2.0-0027377966&partnerID=MN8TOARS.
    10.1055/s-2007-1021207
  670. Gonçalves J; Carvalho F; Guimarães S; Goncalves, J.; Carvalho, F.; Guimaraes, S.; GONCALVES, J; CARVALHO, F; GUIMARAES, S. "Uptake inhibitors do not change the effect of imidazoline alpha 2-adrenoceptor agonists on transmitter release evoked by single pulse stimulation in mouse vas deferens.". Naunyn-Schmiedeberg's archives of pharmacology 339 3 (1989): 288-292. http://europepmc.org/abstract/med/2566931.
    10.1007/bf00173579
Journal issue
  1. Costa, Vera M; Carvalho, Félix. "Pharmacology of Cardiovascular Disease". Biomolecules (2023): https://www.mdpi.com/journal/biomolecules/special_issues/Pharmacology-Cardiovascular.
    In press
Newsletter article
  1. Sousa, Adelaide; Rufino, Ana T.; Ana Ramalho; Carvalho, Félix; Fernandes, Eduarda; Freitas, Marisa. "Intestinal inflammation mediated by silver nanoparticles is prevented by dietary flavonoids", Atlas of Science, 2022, https://atlasofscience.org/intestinal-inflammation-mediated-by-silver-nanoparticles-is-prevented-by-dietary-flavonoids/.
Online resource
  1. Dias-Carvalho, Ana; Reis-Mendes, Ana; Duarte-Araújo, Margarida; Carvalho, Félix; Bastos, Maria Lourdes; Sá, Susana I; Capela, João Paulo; Costa, Vera Marisa. Effects of Doxorubicin and Mitoxantrone in the brain of differently aged mice: in vivo chemobrain study. 2019. https://sciforum.net/paper/view/conference/6364.
  2. Dionísio, Flávio; Araújo, Ana Margarida; Duarte-Araújo, Margarida; Guedes de Pinho, Paula; Bastos, Maria de Lourdes; Carvalho, Félix; Costa, Vera Marisa. Cyclophosphamide main bioactivation products cause disturbance in the metabolome of AC16 cardiac cells at clinically relevant concentrations. 2019. https://sciforum.net/paper/view/conference/6366.
Thesis / Dissertation
  1. Oliveira, Sara. "Targeting Neuroinflammation and Neurodegeneration in Parkinson’s Disease". PhD, 2021. http://hdl.handle.net/10451/54676.
  2. Camões, Sérgio José Póvoas. "Modulating mesenchymal stem cells to overcome impaired wound healing". PhD, 2020. http://hdl.handle.net/10451/48527.

Intellectual property

Patent
  1. Felix Carvalho; Maria de Lourdes Bastos; duarte, ja; Ricardo Jorge Dinis Oliveira; Vera Costa. 2016. "Use of polymyxin as an antidote for intoxications by amatoxins".
  2. Madalena Pinto; Emilia Sousa; Correia-da-Silva, Marta; Franklin Marques; Carvalho, Félix. 2013. "Xantonas sulfatadas e análogos xantónicos glicosilados sulfatados com Actividade anticoagulante e processos para a sua preparação". Portugal.
  3. Dinis-Oliveira, Ricardo Jorge; Baltazar, Maria Teresa; Duarte, José Alberto; Lúcia Guilhermino; Bastos, Maria de Lourdes; Carvalho, Félix. 2012. "Nova formulação do herbicida paraquato". Portugal.
  4. Dinis-Oliveira, Ricardo Jorge; Remiao, Fernando; Duarte, José Alberto Ramos; Navarro, Amparo Sanchez; Bastos, Maria de Lourdes; Carvalho, Félix. 2007. "THE USE OF THE PROCESS OF INDUCTION OF DE NOVO SYNTHESIS OF P-GLYCOPROTEIN (P-GP) IN THE TREATMENT AND PREVENTION OF XENOBIOTIC-INDUCED INTOXICATIONS IN MAMMALS". United States.
  5. Dinis-Oliveira, Ricardo Jorge; Remiao, Fernando; Duarte, José Alberto Ramos; Navarro, Amparo Sanchez; Bastos, Maria de Lourdes; Carvalho, Félix. 2007. "THE USE OF THE SALICYLATE AS AN ANTIDOTE FOR PARAQUAT INTOXICATIONS IN MAMMALS". United States.
  6. Dinis-Oliveira, Ricardo Jorge; Remião, Fernando; Duarte, José Alberto; Navarro, Amparo Sanchez; Bastos, Maria de Lourdes; Carvalho, Félix. 2006. "Utilização do processo de indução da síntese de novo da glicoproteína P (Gp-p) no tratamento das intoxicações dos mamíferos por xenobióticos". Portugal.

Other

Other output
  1. Additional file 4 of Mapping age- and sex-specific HIV prevalence in adults in sub-Saharan Africa, 2000–2018. 2023. Emily Haeuser; Audrey L. Serfes; Michael A. Cork; Mingyou Yang; Hedayat Abbastabar; E S Abhilash; maryam adabi; et al.
    10.60692/gjdr0-7vp33
  2. The overlapping burden of the three leading causes of disability and death in sub-Saharan African children. 2022. Robert C. Reiner; Catherine Welgan; Christopher Troeger; Mathew M Baumann; Daniel Weiss; Aniruddha Deshpande; Brigette; et al.
    10.60692/v67x5-hch11
  3. Targeting Pancreatic Lipase for Obesity Treatment. PhD Seminar. 2022. Rocha, S.; Silva, Artur; Carvalho, Félix; Fernandes, Eduarda.
  4. The burden of injury in Central, Eastern, and Western European sub-region: a systematic analysis from the Global Burden of Disease 2019 Study. Archives of Public Health. 2022. Charalampous, P.; Haagsma, J.A.; Ariani, F.; Gallay, A.; Iburg, K.M.; Nena, E.; Ngwa, C.H.; et al. http://www.scopus.com/inward/record.url?eid=2-s2.0-85166884628&partnerID=MN8TOARS.
    10.21203/rs.3.rs-1292258/v1
  5. Doxorubicin-induced neurotoxicity differently affects the hippocampal formation subregions in adult mice. Heliyon. 2022. Dias-Carvalho, A.; Ferreira, M.; Reis-Mendes, A.; Ferreira, R.; Bastos, M.L.; Fernandes, E.; Sá, S.I.; et al. Corresponding author: Dias-Carvalho, Ana. http://www.scopus.com/inward/record.url?eid=2-s2.0-85167496261&partnerID=MN8TOARS.
    10.21203/rs.3.rs-2285298/v1
  6. Mortality from snakebite envenomation: An analysis from the global burden of disease study 2019. 2021. Roberts, N.; Johnson, E.; Zeng, S.; Hamilton, E.; Abdoli, A.; Alahdab, F.; Alipour, V.; et al. http://www.scopus.com/inward/record.url?eid=2-s2.0-85168016682&partnerID=MN8TOARS.
    10.21203/rs.3.rs-1021472/v1
  7. Epidemiology of injuries from fire, heat and hot substances: global, regional and national morbidity and mortality estimates from the Global Burden of Disease 2017 study. 2019. Spencer James; Lydia R. Lucchesi; Catherine Bisignano; Chris D Castle; Zachary V Dingels; Jack Fox; Erin B Hamilton; et al.
    10.60692/9bd7y-7gg03
  8. Mortality, morbidity, and hospitalisations due to influenza lower respiratory tract infections, 2017: an analysis for the Global Burden of Disease Study 2017. 2019. Christopher Troeger; Brigette; Fakher Rahim; Stephanie R M Zimsen; Samuel B Albertson; Degu Abate; Jemal Abdela; et al.
    10.60692/0qmk4-25n52
  9. The synthetic cannabinoid XLR-11 induces in vitro nephrotoxicity by impairment of endocannabinoid-mediated regulation of mitochondrial function homeostasis and triggering of apoptosis. Synthetic cannabinoids (SCBs)-related intoxications and deaths have been increasingly reported, turning its widespread recreational use into a major public health concern. Specifically, a direct link between SCBs and acute kidney injury (AKI) has been established. XLR-11 is an SCB commonly found in the toxicological analysis of patients with SCB-associated AKI. However, the pathophysiology of AKI. 2018. Faculdade de Farmácia; Silva, J.P.; Carmo, H.; Carvalho, F.. 0378-4274.
    10.1016/j.toxlet.2018.01.023
  10. Healthcare Access and Quality Index based on mortality from causes amenable to personal health care in 195 countries and territories, 1990–2015: a novel analysis from the Global Burden of Disease Study 2015. BACKGROUND: National levels of personal health-care access and quality can be approximated by measuring mortality rates from causes that should not be fatal in the presence of effective medical care (ie, amenable mortality). Previous analyses of mortality amenable to health care only focused on high-income countries and faced several methodological challenges. In the present analysis, we use the h. 2017. Barber, Ryan M; Fullman, Nancy; Sorensen, Reed J D; Bollyky, Thomas; McKee, Martin; Nolte, Ellen; Abajobir, Amanuel Alemu; et al. http://hdl.handle.net/10400.14/23686.
    10.1016/S0140-6736(17)30818-8
  11. Global, regional, and national disability-adjusted life-years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016. Background Measurement of changes in health across locations is useful to compare and contrast changing epidemiological patterns against health system performance and identify specific needs for resource allocation in research, policy development, and programme decision making. Using the Global Burden of Diseases, Injuries, and Risk Factors Study 2016, we drew from two widely used summary measures. 2017. Hay, Simon I; Abajobir, Amanuel Alemu; Abate, Kalkidan Hassen; Abbafati, Cristiana; Abbas, Kaja M; Abd-Allah, Foad; Abdulkader, Rizwan Suliankatchi; et al. http://hdl.handle.net/10400.14/23722.
    10.1016/S0140-6736(17)32130-X
  12. Additional file 1: of Increased red cell distribution width in Fanconi anemia: a novel marker of stress erythropoiesis. 2016. Rosa Sousa; Cristina Gonçalves; Isabel Guerra; Emília Costa; Ana Fernandes; Maria Do Bom Sucesso; Joana Azevedo; et al.
    10.6084/m9.figshare.c.3641411_d1
  13. TOXICITY OF VOLATILE BURN PRODUCTS OFTHE SYNTHETIC CANNABINOID 5F-PB-22 ON NEURONAL, HEPATIC AND CARDIAC CELLS. 2016. Ana Santos-Carvalho; Sónia Ferreira; Ana Margarida Araújo; Paula Guedes; Claudia Cavadas; Félix Carvalho.
    10.13140/rg.2.1.2271.7846
  14. Increased red cell distribution width in Fanconi anemia: a novel marker of stress erythropoiesis. Orphanet Journal of Rare Diseases. 2016. Rosa Sousa; Cristina Gonçalves; Isabel Guerra; Emília Costa; Ana Fernandes; Maria Do Bom Sucesso; Joana Azevedo; et al. http://www.scopus.com/inward/record.url?eid=2-s2.0-84979222169&partnerID=MN8TOARS.
    10.6084/m9.figshare.c.3641411
  15. Evaluation of toxic and protective effects of an essential oil of salvia officinalis L on liver cells. The widespread use of sage (Salvia officinalis L.) in herbal teas and as a food condiment requires that studies of their biological effects are conducted in order to prevent ill effects on human health. It is known that the essential oil (EO) of this plant is neurotoxic, but in higher concentrations than those used in the applications referred above. In this study we have isolated and characterize. 2002. Lima, Cristóvão F.; Carvalho, Felix; Fernandes, Eduarda; Bastos, Maria de Lurdes; Gomes, P. Santos; Ferreira, Manuel Fernandes; Wilson, Cristina Pereira. http://hdl.handle.net/1822/5102.
  16. Hepatotoxicity of an essential oil of Salvia officinalis L.: an in vitro study using freshly isolated rat hepatocytes. Sage (Salvia officinalis L.) is a popular Mediterranean aromatic herb that is cultivated worldwide. It is used since ancient times as a medicinal herb for treating a variety of ailments and has a reputation for memory enhancement [1,2]. It is also commonly used for flavouring and seasoning of foods, most of their properties being due to essential oils [1,3]. Sage extracts have also been reported t. 2001. Lima, Cristóvão F.; Carvalho, Felix; Fernandes, Eduarda; Bastos, Maria de Lurdes; Gomes, P. Santos; Ferreira, Manuel Fernandes; Wilson, Cristina Pereira. http://hdl.handle.net/1822/9192.
Activities

Supervision

Thesis Title
Role
Degree Subject (Type)
Institution / Organization
2024 - 2024 Cardiac remodeling persists as an enduring cardiotoxic effect of doxorubicin and mitoxantrone: insights from non-clinical studies conducted on adult and elderly mice
Co-supervisor
Ciências Farmacêuticas (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2023 - 2023 Synthesis, pharmacological, and toxicological evaluation of carbamate-based melanostatin analogues with potential anti-Parkinson activity
Co-supervisor
Química Farmacêutica (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2022 - 2022 Epigenetic impact of cannabinoid exposure on neurogenesis: a mechanistic approach
Co-supervisor
Ciências Farmacêuticas (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2022 - 2022 O impacto dos canabinoides sintéticos na metilação global do DNA durante a diferenciação neuronal de células NG108-15
Co-supervisor
Toxicologia Analítica Clínica e Forense (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2022 - 2022 In vitro evaluation of telomere length in neuronal cells exposed to therapeutic and recreational opioids
Co-supervisor
Toxicologia Analítica Clínica e Forense (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2022 - 2022 The study of the cardiotoxicity of targeted anticancer drugs: an in vitro metabolomics study
Co-supervisor
Toxicologia Analítica Clínica e Forense (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2022 - 2022 Neuroprotection of Amphetamine and Methylphenidate psychostimulants against dopaminergic neurotoxins in an in vitro Parkinson model
Co-supervisor
Toxicologia Analítica Clínica e Forense (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2021 - 2021 Avaliação da toxicidade do veneno do Echiichtys vipera num modelo de células neuronais SH-SY5Y
Supervisor
Controlo de Qualidade (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2021 - 2021 The neurotoxic mechanisms of new and old anticancer drugs: from in vitro to in vivo studies
Co-supervisor
Ciências Farmacêuticas (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2021 - 2021 Multidisciplinary approach for the development of new flavonoids to tackle obesity
Co-supervisor
Ciências Farmacêuticas (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2020 - 2020 In vitro assessment of the Synthetic Cannabinoids´ impact on mitochondrial function and dynamics during neurodevelopment
Co-supervisor
Ciências Farmacêuticas (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2020 - 2020 Unraveling the involvement of G Protein-coupled receptors in the onset of mood and cognitive adverse events
Co-supervisor
Ciências Farmacêuticas (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2020 - 2020 In vitro assessment of the effects of heroin on telomere length
Co-supervisor
Medicina Legal (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2020 - 2020 Evaluation of epigenetic modifications induced by synthetic cannabinoids during in vitro neuronal differentiation.
Co-supervisor
Toxicologia Analítica Clínica e Forense (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2019 - 2019 Toxicometabolomics of amphetaminic derivates in in vitro and in vivo experimental models
Co-supervisor
Ciências Farmacêuticas (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2018 - 2018 Neurotoxicity of Methylenedioxymethamphetamine (mdma;"ecstasy") on Rat Brain Mitochondria
Supervisor
Toxicologia (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2018 - 2018 In vitro evaluation of antidotes for Amanita Phalloides intoxications
Supervisor
Controlo de Qualidade (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2018 - 2018 Synthetic Cannabinoids In The Regulation of Neuronal Differentiation
Co-supervisor
Toxicologia Analítica Clínica e Forense (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2017 - 2017 Uncovering the hepatotoxic and neurotoxic potential of ß-keto amphetamine (cathinone) derivates: in vitro mechanistic studies.
Co-supervisor
Ciências Farmacêuticas (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2016 - 2016 Neurotoxicity of synthetic cathinones.
Co-supervisor
Farmacologia e Toxicologia Experimentais e Clínicas (associação) (PhD)
Universidade do Porto Faculdade de Medicina, Portugal
2016 - 2016 In Vitro Hepatotoxicity of Sinthetic Cathinones and Benzofurans Used as “Legal Highs"
Co-supervisor
Toxicologia Analítica Clínica e Forense (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2016 - 2016 Deteção e identificação de compostos químicos resultantes da queima de produtos contendo canabinóides sintéticos.
Co-supervisor
Controlo de Qualidade (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2014 - 2014 Krokodil: a new drug, new challenges
Co-supervisor
Ciências Forenses (PhD)
Universidade do Porto Faculdade de Medicina, Portugal
2014 - 2014 Psychoactive substances present in Salvia divinorum acquired in smartshops or in the Internet
Co-supervisor
Ciências Forenses (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2014 - 2014 Substâncias Psicoativas presentes nas Legal Highs Adquiridas nas Smartshops ou pela Internet: Caracterização Química e Estudo da Citotoxicidade In Vitro do Kratom (Mitragyna Speciosa)
Co-supervisor
Toxicologia Analítica Clínica e Forense (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2014 - 2014 Detection and Identification of Pyrolysis Products from the Combustion of Synthetic Cannabinoids
Co-supervisor
Toxicologia Analítica Clínica e Forense (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2014 - 2014 Brain and Peripheral Organ Toxicity of "Ecstasy" in Adolescent Rats in Human Relevant Doses
Co-supervisor
Toxicologia Analítica Clínica e Forense (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2014 - 2014 Determinação de Metabolitos em Cogumelos Tóxicos e Edíveis por Cromatografia Gasosa e Espectrometria de Massa
Co-supervisor
Toxicologia Analítica Clínica e Forense (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2013 - 2013 Toxicological mechanisms of tramadol and tapentadol: biomedical and forensic insights from in vivo studies.
Co-supervisor
Biomedicina (PhD)
Universidade do Porto Faculdade de Medicina, Portugal
2013 - 2013 Psychoactive substances present in "legal highs" acquired in "smartshops" or via internet
Co-supervisor
Ciências Forenses (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2013 - 2013 Drug Abuse Patterns in Coimbra Recreational Nightlife
Supervisor
Medicina Legal (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2013 - 2013 Toxicity of the antitumor drug mitoxantrone in pediatric and adult mice
Co-supervisor
Bioquímica (Master)
Universidade do Porto Faculdade de Ciências, Portugal
2011 - 2011 Discovery of an effective antidote for Amanita Phalloides poisoning
Supervisor
Ciências Farmacêuticas (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2011 - 2011 Targeting CXCR4 with immuno-modified iron oxide nanoparticles for cancer treatment with magnetically-induced hyperthermia. An in vitro approach.
Supervisor
Ciências Farmacêuticas (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2010 - 2010 Biological effects of polyacrylic acid-coated and non-coated superparamagnetic iron oxide nanoparticles in in vitro and in vivo experimental models
Co-supervisor
Ciências Farmacêuticas (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2009 - 2009 Ecstasy´s Neurotoxicity: In Vitro Findings from Mitochondria to the Cell
Supervisor
Ciências Farmacêuticas (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2009 - 2009 New Formulation of Paraquat with Lysine Acetylsalicylate. Safety improvement for mammalian and algae species with maintenance of the herbicidal activity
Supervisor
Ciências Farmacêuticas (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2009 - 2009 Chromosome instability in fanconi anemia: searching for therapeutic drugs to prevent the progression of the disease
Co-supervisor
Ciências Biomédicas (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2009 - 2009 Study of Genetic Factors Involved in Pain Perception and Morphine Analgesia in Cancer-Related Pain
Co-supervisor
Ciências Farmacêuticas (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2007 - 2007 Neurotoxicity of Ecstasy in Rat Cortical Neurons
Supervisor
Toxicologia (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2007 - 2007 Research Into the Machanisms of Paraquat-induced Multiple Organ Failure-development and Application of Antidotes and Antidotal Pathways for the Treatment of Human Poisonings
Supervisor
Toxicologia (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2007 - 2007 Effects of Environmental Contaminants on the Cholinesterasic Function of One Estuarine Species (palaemon Serratus)
Co-supervisor
Ciências Biomédicas (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2006 - 2006 A Hipertensão Causada por um Bloqueador dos Receptores da Adenosina. Papel do Stress Oxidativo
Co-supervisor
Farmacologia (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2005 - 2005 Development of Assays for the Assessment of the Toxicity of Xenobiotics in Salt-water
Co-supervisor
Ciências Biomédicas (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2005 - 2005 Toxicological and Toxicokinetic Interactions Between Ethanol and Ecstasy. in Vivo and in Vitro Studies
Co-supervisor
Toxicologia (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2005 - 2005 Caracterização Fitoquímica e Actividade Antioxidante de Culturas "in Vivo" e "in Vitro" de Brassica Oleracea Var.costata
Co-supervisor
Farmacognosia (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2004 - 2004 Estudos in Vitro da Hepatotoxicidade, Nefrotoxicidade e Cardiotoxicidade da Metilenodioximetanfetamina ("ecstasy") e dos Seus Metabolitos
Supervisor
Toxicologia (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2002 - 2002 Cardiotoxicidade do Isoproterenol e dos Produtos da Sua Oxidação - Estudos Mecanísticos em Suspensões de Cardiomiócitos Isolados de Ratos Adultos
Co-supervisor
Toxicologia (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
Distinctions

Award

2015 Menção honrosa
1998 Primeiro prémio no concurso “Prémios UCB de Farmacologia - Edição de 1998”
1996 Menção honrosa no concurso “Prémios UCB de Farmacologia - Edição de 1996”.
Sociedade Portuguesa de Farmacologia, Portugal

Title

2022 Companheiro Paul Harris, “em reconhecimento à prestação de tangíveis e significantes serviços com o objetivo de fomentar a compreensão e as relações amistosas entre os povos do mundo”
Fundação Rotária do Rotary Internacional, United States

Other distinction

2016 Best poster award to Vânia Vilas Boas for the poster entitled “Targeting chemokine receptor CXCR4 with magnetic particles"
2014 Highly Commended recognition in the 2014 EUROTOX Gerhard-Zbinden Young Scientist Award
EUROTOX, Belgium
2014 Honorable mention award for the manuscript published in Toxicological Sciences, 2014, 139 (2), 407-420.
2013 Alberto Ferrari Poster Prize: Reina-Couto M, Carvalho J, Valente MJ, Vale L, Afonso J, Morato M, Carvalho F, Bettencourt P, Sousa T, Albino-Teixeira A (2013). Lipoxins in chronic heart failure: modulation by low-dose acetylsalicylic acid and statin therap
2011 Medalha de Mérito Municipal
Camara Municipal de santo Tirso, Portugal
2008 Young Scientist Award 2008 for my PhD student Ricardo Dinis-Oliveira
2008 Best Professor AEFFUP 2007/2008
2007 Best oral presentation: “Produção de peróxido de hidrogénio (H2O2) em dois modelos de hipertensão arterial com aumento da angiotensina II” by my PhD student Teresa Sousa
2007 Best poster: “Sodium salicylate: a fully effective antidote against paraquat poisonings in pre-clinical studies”.
2007 Best poster: "Neuropeptide y protects retina neural cells from ecstasy-induced neurotoxicity"
2007 Professor with the best project of the year