Manuel Lemos (4B16-606C-8760)

Curriculum Vitae

Manuel Lemos

Manuel C. Lemos (MLemos) is a Clinical Endocrinologist, Professor of Endocrinology, and Principal Investigator, at the Health Sciences Research Centre, University of Beira Interior (CICS-UBI), Covilhã, Portugal. MLemos holds a Medical Degree (MD) (1995) and an MSc in Cell Biology (2003), from the University of Coimbra, Portugal; and a PhD in Clinical Medicine (2008) from the University of Oxford, UK. MLemos undertook his clinical training at the University Hospital of Coimbra, Portugal, where he completed his medical specialty in Endocrinology & Nutrition (2003). CLINICAL ACTIVITY As a medical specialist in Endocrinology, MLemos dedicates a large fraction of his time to the management of patients with endocrine disorders, in particular patients with diabetes mellitus and its associated complications, thyroid disorders, and other hormone-related disorders. He has worked at several institutions, including University Hospital of Coimbra, Oxford Centre for Diabetes, Endocrinology & Metabolism (OCDEM), UK, Cova da Beira Hospital Centre, Covilhã, and the Portuguese Institute of Oncology, Coimbra, Portugal. SCIENTIFIC ACTIVITY MLemos research interest is the molecular genetics of endocrine disorders. He has carried out genetic and phenotypic studies of several monogenic endocrine disorders, including inherited forms of diabetes mellitus, growth hormone deficiency and hypogonadotropic hypogonadism, and studies of genetic susceptibility to more common multifactorial endocrine disorders such as type 1 diabetes mellitus and thyroid cancer. He is the Coordinator of a nationwide multicentric research project to identify and genetically characterise patients with familial isolated pituitary adenomas. He has received funding from the Portuguese Foundation for Science and Technology, the Portuguese Society of Diabetology, and the Portuguese Society for Endocrinology. MLemos was the national representative in the European Cooperation in Science and Technology (COST) Action BM1105 GnRH Deficiency: Elucidation of the Neuroendocrine Control of Human Reproduction. His work has been funded by the FCT, the Portuguese Society of Endocrinology, Diabetes & Metabolism, the Portuguese Society of Diabetology, and by Regional Strategic Funding. He has received awards from the Portuguese Society of Endocrinology, Diabetes & Metabolism, the Portuguese Society of Diabetology, and the British Endocrine Society. ACADEMIC ACTIVITY MLemos is a Professor of Endocrinology, at the University of Beira Interior (UBI), Covilhã, Portugal. He began his academic career as a Teaching Assistant (1996) in Medical Genetics, at the Faculty of Medicine, University of Coimbra, and later as an Assistant Professor (2008), Associate Professor (2015) and full Professor (2022) in Endocrinology, at UBI. He is currently involved in teaching the undergraduate courses in Medicine and in Pharmaceutical Sciences at UBI, as well as the Doctoral Programme in Medicine at UBI, of which he was the course director between 2009 and 2013. He is regularly invited to lecture at doctoral programmes at other universities and at scientific events organized by the Portuguese Society of Endocrinology, Diabetes & Metabolism, the Portuguese Society of Paediatric Endocrinology, and the Portuguese Society of Obesity. MLemos is currently the President of the Portuguese Board of Medical Specialists in Endocrinology.

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Identification

Personal identification

Full name: Manuel Lemos

Citation names

Lemos, Manuel C
Lemos, Manuel Carlos

Author identifiers

Ciência ID: 4B16-606C-8760
ORCID iD: 0000-0001-9326-8900
Researcher Id: D-9861-2013
Scopus Author Id: 35496279500

Email addresses

mclemos@fcsaude.ubi.pt (Professional)

Telephones

Telephone

275329002 (Professional)

Addresses

(CICS-UBI), Health Sciences Research Centre, University of Beira Interior, 6200-506, Covilhã, Covilhã, Portugal (Professional)

Websites

www.linkedin.com/in/manuel-c-lemos (Personal)

Knowledge fields

Medical and Health Sciences - Clinical Medicine - Endocrinology and Metabolism
Medical and Health Sciences - Basic Medicine - Human Genetics

Languages

Language	Speaking	Reading	Writing	Listening	Peer-review
English	Advanced (C1)	Advanced (C1)	Advanced (C1)	Advanced (C1)
Portuguese	Advanced (C1)	Advanced (C1)	Advanced (C1)	Advanced (C1)

Education

	Degree	Classification
2019 Concluded	Medicina (Medicine) (Título de Agregado) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2008 Concluded	DPhil Clinical Medicine (Doctor of Philosophy) University of Oxford, United Kingdom "Genetic and Phenotypic Studies of the Multiple Endocrine Neoplasia Type 1 Syndrome" (THESIS/DISSERTATION)
2003 Concluded	Mestrado em Biologia Celular (MSc Cell Biology) (Mestrado) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal "Genes de metabolismo de genotóxicos e susceptibilidade para neoplasias hematológicas (Genotoxic metabolizing genes and susceptibility to haematological neoplasias)" (THESIS/DISSERTATION)	Muito Bom
1995 Concluded	Medicina (Medicine) (Licenciatura) Universidade de Coimbra Faculdade de Medicina, Portugal	15

Affiliation

Teaching in Higher Education

	Category Host institution	Employer
2022 - Current	Full Professor (University Teacher)	Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal

2015/06/01 - 2022/03	Associate Professor (University Teacher)	Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal

2008/03/01 - 2015/05/31	Assistant Professor (University Teacher)	Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal

2005/11/14 - 2008/02/29	Invited Assistant (University Teacher)	Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal

2000/08/25 - 2006/03/11	Invited Assistant (University Teacher)	Universidade de Coimbra Faculdade de Medicina, Portugal

1996/04/08 - 2000/08/24	Tutor (University Teacher)	Universidade de Coimbra Faculdade de Medicina, Portugal

Positions / Appointments

	Category Host institution	Employer
2015/06/01 - 2021/05/31	Manager of Laboratory, Institute, Museum, Centre or Observatory	Universidade da Beira Interior - UBImedical, Portugal

2014/05/30 - 2019/03/06	Pro-Rector	Universidade da Beira Interior, Portugal

Others

	Category Host institution	Employer
2023/10/10 - Current	Presidente do Colégio da Especialidade de Endocrinologia (President of the Portuguese Board of Medical Specialists in Endocrinology)	Ordem dos Médicos, Portugal

2006/12 - Current	Médico Endocrinologista (Clinical Endocrinologist)	Private Clinic, Portugal

2011/03 - 2013/06	Médico Endocrinologista (Clinical Endocrinologist)	Instituto Português de Oncologia de Coimbra Francisco Gentil EPE, Portugal

2005/11/14 - 2006/11/30	Médico Endocrinologista (Clinical Endocrinologist)	Centro Hospitalar Cova da Beira EPE, Portugal

2003/10/01 - 2005/10/01	Médico Endocrinologista (Clinical Endocrinologist)	Oxford Centre for Diabetes Endocrinology and Metabolism, United Kingdom

2003/02/26 - 2003/10/01	Médico Endocrinologista (Clinical Endocrinologist)	Hospitais da Universidade de Coimbra, Portugal

1998/01/01 - 2003/02/25	Internato Complementar em Endocrinologia (Residency in Clinical Endocrinology)	Hospitais da Universidade de Coimbra, Portugal

1996/01/01 - 1997/07/30	Internato Geral (General Internship)	Hospitais da Universidade de Coimbra, Portugal

Projects

Contract

	Designation	Funders
2021/07/01 - 2023/06/30	Genome-based personalized medicine CENTRO-08-5864-FSE-000039 Principal investigator Universidade da Beira Interior - Centro de Investigação em Ciências da Saúde (CICS-UBI), Portugal	Comissão de Coordenação e Desenvolvimento Regional do Centro Ongoing
2021 - 2022	Next-generation sequencing for the diagnosis of children with Maturity-Onset Diabetes of the Young (MODY) Bolsa de Endocrinologia, Dra. Conceição Barbas, 2020 Principal investigator Universidade da Beira Interior - Centro de Investigação em Ciências da Saúde (CICS-UBI), Portugal	Sociedade Portuguesa de Endocrinologia, Diabetes e Metabolismo Ongoing
2018/07 - 2021/06	GenoPit - Genetic risk factors for pituitary adenomas: a national, multicenter, genetic and clinical analysis POCI-01-0145-FEDER-029489 Principal investigator Universidade da Beira Interior - Centro de Investigação em Ciências da Saúde (CICS-UBI), Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2019 - 2021	Analysis of the regulation of drug uptake and detoxification systems in the blood-cerebrospinal fluid barrier: the role of sex hormones Bolsa SPEDM para Projeto de Investigação Científica em Endocrinologia 2018 Researcher Universidade da Beira Interior - Centro de Investigação em Ciências da Saúde (CICS-UBI), Portugal	Sociedade Portuguesa de Endocrinologia, Diabetes e Metabolismo Ongoing
2019 - 2021	The choroid plexus as an alternative source of pituitary hormones: analysis of its regulatory mechanisms and secretory profiles Bolsa SPEDM / Novartis Oncology em Patologia Hipofisária 2018 Researcher Universidade da Beira Interior - Centro de Investigação em Ciências da Saúde (CICS-UBI), Portugal	Sociedade Portuguesa de Endocrinologia, Diabetes e Metabolismo Ongoing
2018 - 2020	Whole exome study of a family with congenital hypogonadotropic hypogonadism Bolsa SPEDM / Novartis Oncology em Patologia Hipofisária 2017 Principal investigator Universidade da Beira Interior - Centro de Investigação em Ciências da Saúde (CICS-UBI), Portugal	Sociedade Portuguesa de Endocrinologia, Diabetes e Metabolismo Ongoing
2018 - 2020	Endocrine disruptors: maternal exposure to metals and repercussions on maternal and newborn thyroid function Bolsa Prof. E. Limbert MERCK / SPEDM 2017 Researcher Universidade da Beira Interior - Centro de Investigação em Ciências da Saúde (CICS-UBI), Portugal	Sociedade Portuguesa de Endocrinologia, Diabetes e Metabolismo Ongoing
2018 - 2020	Exposure to endocrine disruptors and association with gestacional diabetes in the first trimester Bolsa Almeida Ruas - Novo Nordisk/SPD 2018 Researcher Universidade da Beira Interior - Centro de Investigação em Ciências da Saúde (CICS-UBI), Portugal	Sociedade Portuguesa de Diabetologia Ongoing
2018 - 2020	Endocrine disruptors and premature menopause: effects of plastics and cosmetics on age of menopause Bolsa de Endocrinologia “Dra. Maria da Conceição Barbas – SPEDM” 2018 Researcher Universidade da Beira Interior - Centro de Investigação em Ciências da Saúde (CICS-UBI), Portugal	Sociedade Portuguesa de Endocrinologia, Diabetes e Metabolismo Ongoing
2018 - 2020	C4-Cloud Computing Competences Centre Centro-01-0145-FEDER-000019 Researcher Universidade da Beira Interior, Portugal	European Regional Development Fund Ongoing
2017 - 2020	Interdisciplinary Challenges on Neurodegeneration (ICON) CENTRO-01-0145-FEDER-000013 Researcher Universidade da Beira Interior - Centro de Investigação em Ciências da Saúde (CICS-UBI), Portugal	Ongoing
2017 - 2019	Iodine deficiency in pregnancy: effects on the cognitive development of children Bolsa de Endocrinologia Dr.ª Maria da Conceição Barbas – SPEDM 2017 Principal investigator Universidade da Beira Interior - Centro de Investigação em Ciências da Saúde (CICS-UBI), Portugal	Sociedade Portuguesa de Endocrinologia, Diabetes e Metabolismo Ongoing
2017 - 2019	Analysis of germline mutations of the AIP and MEN1 genes in patients with young-onset isolated pituitary macroadenomas Bolsa SPEDM / Novartis Oncology em Patologia Hipofisária 2017 Principal investigator Universidade da Beira Interior - Centro de Investigação em Ciências da Saúde (CICS-UBI), Portugal	Sociedade Portuguesa de Endocrinologia, Diabetes e Metabolismo Concluded
2017 - 2019	Type 1 diabetes and vitamin D: a genetic association study Bolsa de Investigação SPEDM 2017 Principal investigator Universidade da Beira Interior - Centro de Investigação em Ciências da Saúde (CICS-UBI), Portugal	Sociedade Portuguesa de Endocrinologia, Diabetes e Metabolismo Concluded
2017 - 2019	R.E.NewAL. SKILLS – Real Estate New Alternative Skills ref. 591861-EPP-1-2017-1-IT-EPPKA2-SSA Researcher Universidade da Beira Interior - UBImedical, Portugal	Concluded
2017 - 2018	Growth Hormone Receptor Gene Polymorphism and the Responsiveness to Recombinant Growth Hormone Therapy in the Portuguese Population Pfizer, ref WI216223 Principal investigator Universidade da Beira Interior - Centro de Investigação em Ciências da Saúde (CICS-UBI), Portugal	Pfizer Biofarmacêutica Sociedade Unipessoal Lda Concluded
2015 - 2018	Projeto Estratégico – CICS-UBI UID/Multi/007097/2013 Researcher Universidade da Beira Interior - Centro de Investigação em Ciências da Saúde (CICS-UBI), Portugal	Fundação para a Ciência e a Tecnologia Concluded
2012 - 2016	GnRH Deficiency: Elucidation of the Neuroendocrine Control of Human Reproduction COST action BM1105 Researcher Universidade da Beira Interior - Centro de Investigação em Ciências da Saúde (CICS-UBI), Portugal	European Cooperation in Science and Technology Concluded
2013 - 2015	Hormonal and inflammatory basis of age-related diseases CENTRO-07-0224-FEDER-002015 Principal investigator Universidade da Beira Interior - Centro de Investigação em Ciências da Saúde (CICS-UBI), Portugal	Concluded
2013 - 2014	Genetic susceptibility to thyroid cancer: effect of polymorphisms of the vitamin D receptor gene Bolsa Prof. E.Limbert SPEDM/Genzyme em Patologia da Tiróide- 2012 Principal investigator Universidade da Beira Interior - Centro de Investigação em Ciências da Saúde (CICS-UBI), Portugal	Sociedade Portuguesa de Endocrinologia, Diabetes e Metabolismo Concluded
2012 - 2014	Monogenic diabetes : from the clinic to the understanding of its aetiology Bolsa NUNO CASTEL-BRANCO / S.P.D. / Lilly Portugal - 2012 Principal investigator Universidade da Beira Interior - Centro de Investigação em Ciências da Saúde (CICS-UBI), Portugal	Sociedade Portuguesa de Diabetologia Concluded
2011 - 2014	Projeto Estratégico – CICS-UBI PEst-C/SAU/UI0709/2011 Researcher Universidade da Beira Interior - Centro de Investigação em Ciências da Saúde (CICS-UBI), Portugal	Fundação para a Ciência e a Tecnologia Concluded
2010/06 - 2013/11	Molecular genetics and functional genomics of pituitary hormone deficiencies PTDC/SAU-GMG/098419/2008 Principal investigator Universidade da Beira Interior - Centro de Investigação em Ciências da Saúde (CICS-UBI), Portugal	Fundação para a Ciência e a Tecnologia, I.P. Concluded
2011 - 2013	TICE.Healthy: Sistemas de Saúde e Qualidade de Vida - Metabolic Care Agência de Inovação - Programa de Apoio QREN - Projetos Mobilizadores Researcher Universidade da Beira Interior - Centro de Investigação em Ciências da Saúde (CICS-UBI), Portugal	Concluded
2009 - 2011	Immunogenetic characterization of type 1 diabetes in the Portuguese population: effect of the C1858T polymorphism in the PTPN22 gene Bolsa Pedro Eurico Lisboa SPD/Bayer 2009 Principal investigator Universidade da Beira Interior - Centro de Investigação em Ciências da Saúde (CICS-UBI), Portugal	Sociedade Portuguesa de Diabetologia Concluded
2005 - 2006	Genetic polymorphisms of interleukin-18 and their contribution to the risk of type 1 diabetes BOLSA DE ESTUDO PEDRO EURICO LISBOA, SPD/BAYER Principal investigator Universidade de Coimbra Faculdade de Medicina, Portugal	Sociedade Portuguesa de Diabetologia Concluded
2004 - 2005	Genetic susceptibility to type 1 diabetes: effect of genetic polymorphsms of CTLA4 and VDR SOCIEDADE PORTUGUESA DE DIABETOLOGIA Principal investigator Universidade de Coimbra Faculdade de Medicina, Portugal	Sociedade Portuguesa de Diabetologia Concluded
2004 - 2005	PROP1 gene analysis in Portuguese patients with combined pituitary hormone deficiency FMUC Principal investigator Universidade de Coimbra Faculdade de Medicina, Portugal	Universidade de Coimbra Faculdade de Medicina Concluded
2001 - 2003	Genetic susceptibility to Graves' disease: effect of genetic polymorphsms of CTLA4 and VDR DR edital n.º 88/2001 (2ª série) Principal investigator Universidade de Coimbra Faculdade de Medicina, Portugal	Ministério da Saúde Concluded

Outputs

Publications

Book chapter	Lemos, Manuel C; Teh, B; Thakker, RV. "Multiple Endocrine Neoplasia type 1 (MEN1)". In Encyclopedia of Cancer, edited by Schwab, M, 1-5. Germany: Springer-Verlag Berlin Heidelberg, 2015. Published Lemos, Manuel C; Teh, B; Thakker, RV. "Multiple Endocrine Neoplasia type 1 (MEN1)". In Encyclopedia of Cancer, edited by Schwab M, 1970-1974. New York, United States: Springer Berlin Heidelberg, 2008. Published Regateiro, FJ; Lemos, Manuel C; Coimbra, HA. "Molecular Biology of Endometrial Carcinoma". In Endometrial Cancer, edited by European Board & College of Gynaecology and Obstetrics (eds.), 79-86. Amsterdam, Netherlands: Elsevier Science, 2003. Published Regateiro, FJ; Coimbra, HA; Lemos, Manuel C. "Terapia génica e patologia pulmonar". In Tratado de Pneumologia, 319-326. Lisboa, Portugal: Sociedade Portuguesa de Pneumologia, 2003. Published Lemos, Manuel C; Regateiro, FJ. "Genética e Cancro do Ovário". In Manual de Ginecologia Volume II – Genética e Cancro Ginecológico e da Mama, 109-130. Coimbra, Portugal: Serviço de Ginecologia dos Hospitais da Universidade de Coimbra, 2002. Published Regateiro, FJ; Silva, HC; Lemos, Manuel C. "Genes e Cancro". In Manual de Ginecologia Volume II – Genética e Cancro Ginecológico e da Mama, 9-32. Coimbra, Portugal: Serviço de Ginecologia dos Hospitais da Universidade de Coimbra, 2002.
Journal article	Lopes, Carla A.; Duarte, Marta; Prazeres, Susana; Carvalho, Ivone; Vilarinho, Laura; Martinez-de-Oliveira, José; Limbert, Edward; Lemos, Manuel C.. "Maternal Urinary Iodine Concentration during Pregnancy and Its Impact on Child Growth and Neurodevelopment: An 11-Year Follow-Up Study". Nutrients 15 20 (2023): 4447. http://dx.doi.org/10.3390/nu15204447. 10.3390/nu15204447 Furtado A; Costa D; Lemos MC; Cavaco JE; Santos CRA; Quintela T. "The impact of biological clock and sex hormones on the risk of disease.". Adv Protein Chem Struct Biol. 137 (2023): 39-81. Gonçalves, Catarina I.; Carriço, Josianne N.; Omar, Omneya M.; Abdalla, Ebtesam; Lemos, Manuel C.. "Hypoparathyroidism, deafness and renal dysplasia syndrome caused by a GATA3 splice site mutation leading to the activation of a cryptic splice site". Frontiers in Endocrinology 14 (2023): http://dx.doi.org/10.3389/fendo.2023.1207425. 10.3389/fendo.2023.1207425 Gaspar, L. M.; Gonçalves, C. I.; Saraiva, C.; Cortez, L.; Amaral, C.; Nobre, E.; Lemos, M. C.. "Low frequency of AIP mutations in patients with young-onset sporadic pituitary macroadenomas". Journal of Endocrinological Investigation 46 11 (2023): 2299-2307. http://dx.doi.org/10.1007/s40618-023-02083-7. 10.1007/s40618-023-02083-7 Mineiro, Rafael; Santos, Cecília; Gonçalves, Isabel; Lemos, Manuel; Cavaco, José Eduardo B.; Quintela, Telma. "Regulation of ABC transporters by sex steroids may explain differences in drug resistance between sexes". Journal of Physiology and Biochemistry 79 3 (2023): 467-487. http://dx.doi.org/10.1007/s13105-023-00957-1. 10.1007/s13105-023-00957-1 Gaspar, Leonor M.; Gonçalves, Catarina I.; Fonseca, Fernando; Carvalho, Davide; Cortez, Luísa; Palha, Ana; Barros, Inês F.; et al. Corresponding author: Lemos, Manuel C.. "A Common Variant in the CDK8 Gene Is Associated with Sporadic Pituitary Adenomas in the Portuguese Population: A Case-Control Study". International Journal of Molecular Sciences 23 19 (2022): 11749. http://dx.doi.org/10.3390/ijms231911749. 10.3390/ijms231911749 Gonçalves, Catarina I.; Carriço, Josianne; Bastos, Margarida; Lemos, Manuel C.. "Disorder of Sex Development Due to 17-Beta-Hydroxysteroid Dehydrogenase Type 3 Deficiency: A Case Report and Review of 70 Different HSD17B3 Mutations Reported in 239 Patients". International Journal of Molecular Sciences 23 17 (2022): 10026. http://dx.doi.org/10.3390/ijms231710026. 10.3390/ijms231710026 Fadiga, Lúcia; Lavrador, Mariana; Vicente, Nuno; Barros, Luísa; Gonçalves, Catarina I.; Al-Naama, Asma; Saraiva, Luis R.; Lemos, Manuel C.. "A Novel FGFR1 Missense Mutation in a Portuguese Family with Congenital Hypogonadotropic Hypogonadism". International Journal of Molecular Sciences 23 8 (2022): 4423. http://dx.doi.org/10.3390/ijms23084423. 10.3390/ijms23084423 Lopes, Carla A.; Prazeres, Susana; Martinez-de-Oliveira, José; Limbert, Edward; Lemos, Manuel C.. "Iodine Supplementation in Pregnancy in an Iodine-Deficient Region: A Cross-Sectional Survey". Nutrients 14 7 (2022): 1393. http://dx.doi.org/10.3390/nu14071393. 10.3390/nu14071393 Selvaraj, Senthil; Rodrigues, Dírcea; Krishnamoorthy, Navaneethakrishnan; Fakhro, Khalid A.; Saraiva, Luís R.; Lemos, Manuel C.. "Clinical, Genetic and Functional Characterization of a Novel AVPR2 Missense Mutation in a Woman with X-Linked Recessive Nephrogenic Diabetes Insipidus". Journal of Personalized Medicine 12 1 (2022): 118. http://dx.doi.org/10.3390/jpm12010118. 10.3390/jpm12010118 Rocha, Sandra M.; Sousa, Inês; Gomes, Inês M.; Arinto, Patrícia; Costa-Pinheiro, Pedro; Coutinho, Eduarda; Santos, Cecília R.; et al. "Promoter Demethylation Upregulates STEAP1 Gene Expression in Human Prostate Cancer: In Vitro and In Silico Analysis". Life 11 11 (2021): 1251. http://dx.doi.org/10.3390/life11111251. 10.3390/life11111251 Castro-Vale, Ivone; Durães, Cecília; van Rossum, Elisabeth F. C.; Staufenbiel, Sabine M.; Severo, Milton; Lemos, Manuel C.; Carvalho, Davide. "The Glucocorticoid Receptor Gene (NR3C1) 9ß SNP Is Associated with Posttraumatic Stress Disorder". Healthcare 9 2 (2021): 173. http://dx.doi.org/10.3390/healthcare9020173. 10.3390/healthcare9020173 Alvelos, Maria Inês; Francisco, Ângela; Gomes, Leonor; Paiva, Isabel; Melo, Miguel; Marques, Pedro; Gama-de-Sousa, Susana; et al. "Familial neurohypophyseal diabetes insipidus: clinical, genetic and functional studies of novel mutations in the arginine vasopressin gene". Pituitary (2021): http://dx.doi.org/10.1007/s11102-020-01119-y. 10.1007/s11102-020-01119-y Costa-Brito, Ana R.; Quintela, Telma; Gonçalves, Isabel; Duarte, Ana C.; Costa, Ana R.; Arosa, Fernando A.; Cavaco, José E.; Lemos, Manuel C.; Santos, Cecília R. A.. "The Choroid Plexus Is an Alternative Source of Prolactin to the Rat Brain". Molecular Neurobiology (2021): http://dx.doi.org/10.1007/s12035-020-02267-9. 10.1007/s12035-020-02267-9 Duarte, Ana C.; Furtado, André; Hrynchak, Mariya V.; Costa, Ana R.; Talhada, Daniela; Gonçalves, Isabel; Lemos, Manuel C.; Quintela, Telma; Santos, Cecília R.A.. "Age, Sex Hormones, and Circadian Rhythm Regulate the Expression of Amyloid-Beta Scavengers at the Choroid Plexus". International Journal of Molecular Sciences 21 18 (2020): 6813. http://dx.doi.org/10.3390/ijms21186813. 10.3390/ijms21186813 Furtado, André; Astaburuaga, Rosario; Costa, Ana; Duarte, Ana C.; Gonçalves, Isabel; Cipolla-Neto, José; Lemos, Manuel C.; et al. "The Rhythmicity of Clock Genes is Disrupted in the Choroid Plexus of the APP/PS1 Mouse Model of Alzheimer’s Disease". Journal of Alzheimer's Disease 77 2 (2020): 795-806. http://dx.doi.org/10.3233/jad-200331. 10.3233/jad-200331 Almeida, Joana T.; Rodrigues, Dircea; Guimarães, Joana; Lemos, Manuel C.. "Vitamin D Pathway Genetic Variation and Type 1 Diabetes: A Case-Control Association Study". Genes 11 8 (2020): 897. http://dx.doi.org/10.3390/genes11080897. 10.3390/genes11080897 Lemos, Manuel C.; Thakker, Rajesh V.. "Hypoparathyroidism, deafness, and renal dysplasia syndrome: 20 Years after the identification of the first GATA3 mutations". Human Mutation 41 8 (2020): 1341-1350. http://dx.doi.org/10.1002/humu.24052. 10.1002/humu.24052 Costa, Carla; Coutinho, Eduarda; Santos-Silva, Rita; Castro-Correia, Cíntia; Lemos, Manuel Carlos; Fontoura, Manuel. "Neonatal presentation of growth hormone deficiency in CHARGE syndrome: the benefit of early treatment on long-term growth". Archives of Endocrinology and Metabolism (2020): http://dx.doi.org/10.20945/2359-3997000000231. 10.20945/2359-3997000000231 Alvelos, Maria I.; Gonçalves, Catarina I.; Coutinho, Eduarda; Almeida, Joana T.; Bastos, Margarida; Sampaio, Maria L.; Melo, Miguel; et al. "Maturity-Onset Diabetes of the Young (MODY) in Portugal: Novel GCK, HNFA1 and HNFA4 Mutations". Journal of Clinical Medicine 9 1 (2020): 288. http://dx.doi.org/10.3390/jcm9010288. 10.3390/jcm9010288 Lorigo, Margarida; Mariana, Melissa; Oliveira, Nelson; Lemos, Manuel C.; Cairrao, Elisa. "Vascular Pathways of Testosterone: Clinical Implications". Journal of Cardiovascular Translational Research 13 1 (2019): 55-72. http://dx.doi.org/10.1007/s12265-019-09939-5. 10.1007/s12265-019-09939-5 Lorigo, Margarida; Mariana, Melissa; Lemos, Manuel C.; Cairrao, Elisa. "Vascular mechanisms of testosterone: The non-genomic point of view". The Journal of Steroid Biochemistry and Molecular Biology 196 (2019): 105496. http://dx.doi.org/10.1016/j.jsbmb.2019.105496. 10.1016/j.jsbmb.2019.105496 Tomás, Joana; Santos, Cecília R.A.; Duarte, Ana C.; Maltez, Maria; Quintela, Telma; Lemos, Manuel C.; Gonçalves, Isabel. "Bitter taste signaling mediated by Tas2r144 is down-regulated by 17ß-estradiol and progesterone in the rat choroid plexus". Molecular and Cellular Endocrinology 495 (2019): 110521. http://dx.doi.org/10.1016/j.mce.2019.110521. 10.1016/j.mce.2019.110521 Serra, Carlos; Silveira, Luís; Canudo, António; Lemos, Manuel C.. "Parathyroid identification by autofluorescence: preliminary report on five cases of surgery for primary hyperparathyroidism". BMC Surgery 19 1 (2019): 120. http://dx.doi.org/10.1186/s12893-019-0590-9. 10.1186/s12893-019-0590-9 Carvalho, Isabel S.; Gonçalves, Catarina I.; Almeida, Joana T.; Azevedo, Teresa; Martins, Teresa; Rodrigues, Fernando J.; Lemos, Manuel C.. "Association of Vitamin D Pathway Genetic Variation and Thyroid Cancer". Genes 10 8 (2019): 572. http://dx.doi.org/10.3390/genes10080572. 10.3390/genes10080572 Marques, Bernardo; Couto, Joana; Lemos, Manuel C.; Rodrigues, Fernando. "Reninoma: Uma Causa Rara de Hipertensão Endócrina". Acta Médica Portuguesa 32 13 (2019): http://dx.doi.org/10.20344/amp.11660. 10.20344/amp.11660 Coutinho, Eduarda; Brandão, Carla Maria; Lemos, Manuel Carlos. "Combined Pituitary Hormone Deficiency Caused by a Synonymous HESX1 Gene Mutation". The Journal of Clinical Endocrinology & Metabolism 104 7 (2019): 2851-2854. http://dx.doi.org/10.1210/jc.2019-00081. 10.1210/jc.2019-00081 Lorigo, Margarida; Quintaneiro, Carla; Lemos, Manuel; Martinez-de-Oliveira, José; Breitenfeld, Luiza; Cairrao, Elisa. "UV-B Filter Octylmethoxycinnamate Induces Vasorelaxation by Ca2+ Channel Inhibition and Guanylyl Cyclase Activation in Human Umbilical Arteries". International Journal of Molecular Sciences 20 6 (2019): 1376. http://dx.doi.org/10.3390/ijms20061376. 10.3390/ijms20061376 Gonçalves, Catarina Inês; Patriarca, Filipa Marina; Aragüés, José Maria; Carvalho, Davide; Fonseca, Fernando; Martins, Sofia; Marques, Olinda; et al. "High frequency of CHD7 mutations in congenital hypogonadotropic hypogonadism". Scientific Reports 9 1 (2019): 1597. http://dx.doi.org/10.1038/s41598-018-38178-y. 10.1038/s41598-018-38178-y Orabona, Ciriana; Mondanelli, Giada; Pallotta, Maria T.; Carvalho, Agostinho; Albini, Elisa; Fallarino, Francesca; Vacca, Carmine; et al. "Deficiency of immunoregulatory indoleamine 2,3-dioxygenase 1 in juvenile diabetes". JCI Insight 3 6 (2018): 96244. http://dx.doi.org/10.1172/jci.insight.96244. 10.1172/jci.insight.96244 Horta, M; Lino, C; Lemos, M C. "Hypoparathyroidism, deafness and renal dysplasia (HDR) syndrome and GATA3". QJM: An International Journal of Medicine 110 12 (2017): 837-838. http://dx.doi.org/10.1093/qjmed/hcx176. 10.1093/qjmed/hcx176 Gonçalves, Catarina I; Aragüés, José M; Bastos, Margarida; Barros, Luísa; Vicente, Nuno; Carvalho, Davide; Lemos, Manuel C. "GNRHR biallelic and digenic mutations in patients with normosmic congenital hypogonadotropic hypogonadism". Endocrine Connections 6 6 (2017): 360-366. http://dx.doi.org/10.1530/ec-17-0104. 10.1530/ec-17-0104 COST Action BM1105; Badiu, Corin; Bonomi, Marco; Borshchevsky, Ivan; Cools, Martine; Craen, Margarita; Ghervan, Cristina; et al. "Developing and evaluating rare disease educational materials co-created by expert clinicians and patients: the paradigm of congenital hypogonadotropic hypogonadism". Orphanet Journal of Rare Diseases 12 1 (2017): 57. http://dx.doi.org/10.1186/s13023-017-0608-2. 10.1186/s13023-017-0608-2 Gonçalves, C.I.; Fonseca, F.; Borges, T.; Cunha, F.; Lemos, M.C.. "Expanding the genetic spectrum of ANOS1 mutations in patients with congenital hypogonadotropic hypogonadism". Human Reproduction 32 3 (2017): 704-711. http://dx.doi.org/10.1093/humrep/dew354. 10.1093/humrep/dew354 Raimundo, Joana; Alvelos, Maria I.; Azevedo, Teresa; Martins, Teresa; Rodrigues, Fernando J.; Lemos, Manuel C.. "Association of FOXE1 polyalanine repeat region with thyroid cancer is dependent on tumour size". Clinical Endocrinology 86 2 (2016): 243-246. http://dx.doi.org/10.1111/cen.13166. 10.1111/cen.13166 Infante, Joana B.; Alvelos, Maria I.; Bastos, Margarida; Carrilho, Francisco; Lemos, Manuel C.. "Complete androgen insensitivity syndrome caused by a novel splice donor site mutation and activation of a cryptic splice donor site in the androgen receptor gene". The Journal of Steroid Biochemistry and Molecular Biology 155 (2016): 63-66. http://dx.doi.org/10.1016/j.jsbmb.2015.09.042. 10.1016/j.jsbmb.2015.09.042 Gonçalves, Catarina; Bastos, Margarida; Pignatelli, Duarte; Borges, Teresa; Aragüés, José M.; Fonseca, Fernando; Pereira, Bernardo D.; Socorro, Sílvia; Lemos, Manuel C.. "Novel FGFR1 mutations in Kallmann syndrome and normosmic idiopathic hypogonadotropic hypogonadism: evidence for the involvement of an alternatively spliced isoform". Fertility and Sterility 104 5 (2015): 1261-1267.e1. http://dx.doi.org/10.1016/j.fertnstert.2015.07.1142. 10.1016/j.fertnstert.2015.07.1142 Lemos, Manuel C.; Christie, Paul T.; Rodrigues, Dírcea; Thakker, Rajesh V.. "Pseudohypoparathyroidism type 1a due to a novel mutation in the GNAS gene". Clinical Endocrinology 84 3 (2015): 463-465. http://dx.doi.org/10.1111/cen.12953. 10.1111/cen.12953 Dusatkova, Petra; Pfäffle, Roland; Brown, Milton R; Akulevich, Natallia; Arnhold, Ivo JP; Kalina, Maria A; Kot, Karolina; et al. "Genesis of two most prevalent PROP1 gene variants causing combined pituitary hormone deficiency in 21 populations". European Journal of Human Genetics 24 3 (2015): 415-420. http://dx.doi.org/10.1038/ejhg.2015.126. 10.1038/ejhg.2015.126 Alvelos, Maria Inês; Rodrigues, Magda; Lobo, Luísa; Medeira, Ana; Sousa, Ana Berta; Simão, Carla; Lemos, Manuel Carlos. "A Novel Mutation of the HNF1B Gene Associated With Hypoplastic Glomerulocystic Kidney Disease and Neonatal Renal Failure". Medicine 94 7 (2015): e469. http://dx.doi.org/10.1097/md.0000000000000469. 10.1097/md.0000000000000469 Lemos, Manuel C.; Thakker, Rajesh V.. "GNAS Mutations in Pseudohypoparathyroidism Type 1a and Related Disorders". Human Mutation 36 1 (2014): 11-19. http://dx.doi.org/10.1002/humu.22696. 10.1002/humu.22696 Santos, Marina; Azevedo, Teresa; Martins, Teresa; Rodrigues, Fernando J.; Lemos, Manuel C.. "Association of RET Genetic Polymorphisms and Haplotypes with Papillary Thyroid Carcinoma in the Portuguese Population: A Case-Control Study". PLoS ONE 9 10 (2014): e109822. http://dx.doi.org/10.1371/journal.pone.0109822. 10.1371/journal.pone.0109822 Walls, G. V.; Lemos, M. C.; Javid, M.; Bazan-Peregrino, M.; Jeyabalan, J.; Reed, A. A. C.; Harding, B.; et al. "MEN1 Gene Replacement Therapy Reduces Proliferation Rates in a Mouse Model of Pituitary Adenomas". Cancer Research 72 19 (2012): 5060-5068. http://dx.doi.org/10.1158/0008-5472.can-12-1821. 10.1158/0008-5472.can-12-1821 Hannan, F.M.; Nesbit, M.A.; Zhang, C.; Cranston, T.; Curley, A.J.; Harding, B.; Fratter, C.; et al. "Identification of 70 calcium-sensing receptor mutations in hyper- and hypo-calcaemic patients: Evidence for clustering of extracellular domain mutations at calcium-binding sites". Human Molecular Genetics 21 12 (2012): 2768-2778. http://www.scopus.com/inward/record.url?eid=2-s2.0-84861734350&partnerID=MN8TOARS. 10.1093/hmg/dds105 Lemos, M.C.; Coutinho, E.; Gomes, L.; Bastos, M.; Fagulha, A.; Barros, L.; Carrilho, F.; et al. "The CTLA4 +49 A/G polymorphism is not associated with susceptibility to type 1 diabetes mellitus in the Portuguese population: Short Communication". International Journal of Immunogenetics 36 3 (2009): 193-194. http://www.scopus.com/inward/record.url?eid=2-s2.0-65649105810&partnerID=MN8TOARS. 10.1111/j.1744-313X.2009.00844.x Harding, B.; Lemos, M.C.; Reed, A.A.C.; Walls, G.V.; Jeyabalan, J.; Bowl, M.R.; Tateossian, H.; et al. "Multiple endocrine neoplasia type 1 knockout mice develop parathyroid, pancreatic, pituitary and adrenal tumours with hypercalcaemia, hypophosphataemia and hypercorticosteronaemia". Endocrine-Related Cancer 16 4 (2009): 1313-1327. http://www.scopus.com/inward/record.url?eid=2-s2.0-72549106938&partnerID=MN8TOARS. 10.1677/ERC-09-0082 Lemos, M.C.; Harding, B.; Reed, A.A.C.; Jeyabalan, J.; Walls, G.V.; Bowl, M.R.; Sharpe, J.; et al. "Genetic background influences embryonic lethality and the occurrence of neural tube defects in Men1 null mice: Relevance to genetic modifiers". Journal of Endocrinology 203 1 (2009): 133-142. http://www.scopus.com/inward/record.url?eid=2-s2.0-70349776908&partnerID=MN8TOARS. 10.1677/JOE-09-0124 Lemos, M.C.; Coutinho, E.; Gomes, L.; Carrilho, F.; Rodrigues, F.; Regateiro, F.J.; Carvalheiro, M.. "Combined GSTM1 and GSTT1 null genotypes are associated with a lower risk of papillary thyroid cancer". Journal of Endocrinological Investigation 31 6 (2008): 542-545. http://www.scopus.com/inward/record.url?eid=2-s2.0-48449089834&partnerID=MN8TOARS. Lemos, M.C.; Fagulha, A.; Coutinho, E.; Gomes, L.; Bastos, M.; Barros, L.; Carrilho, F.; et al. "Lack of association of vitamin D receptor gene polymorphisms with susceptibility to type 1 diabetes mellitus in the Portuguese population". Human Immunology 69 2 (2008): 134-138. http://www.scopus.com/inward/record.url?eid=2-s2.0-40949162023&partnerID=MN8TOARS. 10.1016/j.humimm.2008.01.008 Lemos, M.C.; Thakker, R.V.. "Multiple endocrine neoplasia type 1 (MEN1): Analysis of 1336 mutations reported in the first decade following identification of the gene". Human Mutation 29 1 (2008): 22-32. http://www.scopus.com/inward/record.url?eid=2-s2.0-38149112594&partnerID=MN8TOARS. 10.1002/humu.20605 Lemos, M.C.; Carrilho, F.; Rodrigues, F.; Coutinho, E.; Gomes, L.; Carvalheiro, M.; Regateiro, F.J.. "Genetic polymorphism of CYP2D6 influences susceptibility to papillary thyroid cancer". Clinical Endocrinology 67 2 (2007): 180-183. http://www.scopus.com/inward/record.url?eid=2-s2.0-34447512808&partnerID=MN8TOARS. 10.1111/j.1365-2265.2007.02858.x Lemos, M.C.; Harding, B.; Shalet, S.M.; Thakker, R.V.. "A novel MEN1 intronic mutation associated with multiple endocrine neoplasia type 1". Clinical Endocrinology 66 5 (2007): 709-713. http://www.scopus.com/inward/record.url?eid=2-s2.0-34247895523&partnerID=MN8TOARS. 10.1111/j.1365-2265.2007.02806.x Lemos, M.C.; Gomes, L.; Bastos, M.; Leite, V.; Limbert, E.; Carvalho, D.; Bacelar, C.; et al. "PROP1 gene analysis in Portuguese patients with combined pituitary hormone deficiency". Clinical Endocrinology 65 4 (2006): 479-485. http://www.scopus.com/inward/record.url?eid=2-s2.0-33748782519&partnerID=MN8TOARS. 10.1111/j.1365-2265.2006.02617.x Gomes, L.; Lemos, M.C.; Paiva, I.; Ribeiro, C.; Carvalheiro, M.; Regateiro, F.J.. "CYP2D6 genetic polymorphisms are associated with susceptibility to pituitary tumors". Acta Medica Portuguesa 18 5 (2005): 339-344. http://www.scopus.com/inward/record.url?eid=2-s2.0-32044432860&partnerID=MN8TOARS. Lemos, M.C.; Kotanko, P.; Christie, P.T.; Harding, B.; Javor, T.; Smith, C.; Eastell, R.; Thakker, R.V.. "A novel EXT1 splice site mutation in a kindred with hereditary multiple exostosis and osteoporosis". Journal of Clinical Endocrinology and Metabolism 90 9 (2005): 5386-5392. http://www.scopus.com/inward/record.url?eid=2-s2.0-24344507232&partnerID=MN8TOARS. 10.1210/jc.2004-2520 Martins, T.D.; Carrilho, F.; Leitão, P.; Lemos, M.C.; Campos, M.V.; Geraldes, E.; Carvalheiro, M.. "Anaplastic thyroid tumor: Retrospective analysis of 12 cases \| Carcinoma anaplásico da tiróide: Análise retrospectiva de 12 casos". Acta Medica Portuguesa 17 5 (2004): 349-352. http://www.scopus.com/inward/record.url?eid=2-s2.0-14644415890&partnerID=MN8TOARS. Lemos, M.C.; Carrilho, F.; Rodrigues, F.J.; Carvalheiro, M.; Regateiro, F.J.; Ruas, M.M.A.. "Molecular characterisation of a kindred with MEN2A and clinical implications \| Caracterização molecular de uma família com NEM2A e suas implicações clínicas". Acta Medica Portuguesa 16 4 (2003): 245-250. http://www.scopus.com/inward/record.url?eid=2-s2.0-9744232170&partnerID=MN8TOARS. Bastos, M.; Baptista, C.; Campos, M.V.; Alves, R.; Freitas, L.; Bastos, C.; Leitão, P.; et al. "Kidney transplantation and diabetes: Posttransplantation malignancy". Transplantation Proceedings 35 3 (2003): 1098-1099. http://www.scopus.com/inward/record.url?eid=2-s2.0-12444256999&partnerID=MN8TOARS. 10.1016/S0041-1345(03)00324-5 Martins, T.; Bastos, M.; Tomé, L.; Lemos, M.; Batista, C.; Carvalheiro, M.; Ruas, M.M.A.. "Lipoatrophic diabetes: Case report \| Diabetes lipoatrófica: Caso clínico". Arquivos de Medicina 17 1-3 (2003): 117-118. http://www.scopus.com/inward/record.url?eid=2-s2.0-0042928406&partnerID=MN8TOARS. Campos, M.V.; Bastos, M.; Martins, T.; Leitão, P.; Lemos, M.; Carvalheiro, M.; Ruas, E.A.. "Diabetic hiperosmolality: Retrospective study of 60 cases \| Hiperosmolaridade diabética: Análise retrospectiva de 60 casos". Acta Medica Portuguesa 16 1 (2003): 13-19. http://www.scopus.com/inward/record.url?eid=2-s2.0-0038623544&partnerID=MN8TOARS. Lemos, M.C.; Carrilho, F.; Rodrigues, F.J.; Santos, P.; Carvalheiro, M.; Ruas, M.A.; Regateiro, F.J.. "Early onset of medullary thyroid carcinoma in a kindred with multiple endocrine neoplasia type IIA associated with cutaneous lichen amyloidosis". Endocrine Practice 8 1 (2002): 19-22. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036161548&partnerID=MN8TOARS. Baptista, C.; Bastos, M.; Paiva, S.; Martins, T.; Leitão, P.; Lemos, M.; Alves, R.; et al. "Diabetic nephropathy: Results of preoperative evaluation for renal transplantation \| Nefropatia diabética: Protocolo de estudo pré-transplantação renal". Acta Medica Portuguesa 15 1 (2002): 5-10. http://www.scopus.com/inward/record.url?eid=2-s2.0-0038895470&partnerID=MN8TOARS. Lemos, M.C.; Cabrita, F.J.; Silva, H.A.; Vivan, M.; Plácido, F.; Regateiro, F.J.. "Genetic polymorphism of CYP2D6, GSTM1 and NAT2 and susceptibility to haematological neoplasias". Carcinogenesis 20 7 (1999): 1225-1229. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032811583&partnerID=MN8TOARS. 10.1093/carcin/20.7.1225 Lemos, M.C.; Regateiro, F.J.. "N-acetyltransferase genotypes in the Portuguese population". Pharmacogenetics 8 6 (1998): 561-564. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032441668&partnerID=MN8TOARS.
Thesis / Dissertation	Lemos, Manuel C. "Genetic and Phenotypic Studies of the Multiple Endocrine Neoplasia Type 1 Syndrome (D.Phil. Clinical Medicine, University of Oxford, 2008)". PhD, University of Oxford, 2008. Lemos, Manuel C. "Genotoxic metabolizing genes and susceptibility to haematological neoplasias (MSc Cell Biology, University of Coimbra, 2003)". Master, Universidade de Coimbra Faculdade de Ciencias e Tecnologia, 2003.

Activities

Oral presentation

	Presentation title	Event name Host (Event location)
2010	Javid M, Walls G, Lemos MC, Jeyabalan J, Bazan-Peregrino M, Tyler D, Stuckey D, Seymour L, Thakker R. Men1 gene replacement therapy using a modified adenoviral vector demonstrates reduced proliferation rates in pituitary tumours from mice deleted for a multiple endocrine neoplasia type 1 allele. Society for Endocrinology BES 2010, Manchester, UK, 15 to 18-3-2010.
2007	Lemos MC, Harding B, Bowl M, Reed A, Tateossian H, Hough T, Fraser W, Cheeseman M, Thakker RV. Mice deleted for a Multiple Endocrine Neoplasia Type 1 (MEN1) allele develop pancreatic, pituitary and parathyroid tumours in association with hypercalcaemia. UK and Ireland Neuroendocrine Tumour Society (UKI NETS) 5th National Conference, The Royal Society of Medicine, London, UK, 3-12-2007.
2007	Lemos MC, Harding B, Bowl M, Reed A, Tateossian H, Hough T, Fraser W, Cheeseman M, Thakker RV. Mice deleted for a Multiple Endocrine Neoplasia Type 1 (MEN1) allele develop pancreatic, pituitary and parathyroid tumours in association with hypercalcaemia. Society for Endocrinology BES 2007, Birmingham, UK, 5 to 8-3-2007. (Young Endocrinologist Prize awarded by the British Endocrine Society)
2001	Lemos MC, Gomes L, Santos P, Carvalheiro M, Regateiro FJ, Ruas MMA. Homozygous 2-bp deletion (A301G302del) in the PROP1 gene in two kindreds with combined pituitary hormone deficiency. 5th European Congress of Endocrinology, Turin, Italy, 9 to 13-6-2001.
1996	Lemos MC, Regateiro FJ. Genetic polymorphism of GSTM1 and CYP2D6 genes and susceptibility to haematological malignancies. 12th International Medical Sciences Student Congress, Istanbul, Turkey, 15 to 18-5-1996.
1996	Lemos MC, Regateiro FJ. Genetic polymorphism of GSTM1 and CYP2D6 genes and susceptibility to haematological malignancies. 2nd European Medical Students’ Symposium, Thessaloniki, Greece, 3 to 5-5-1996.
1995	Lemos MC, Simão A, Regateiro FJ. Deletion of the GSTM1 gene and cancer susceptibility. 6th European Students’ Conference at the Charité, Berlin, Germany, 19 to 21-10-1995.
1995	Lemos MC, Varejão PM, Regateiro FJ. Genetic polymorphism of P450 cytochrome affecting cancer susceptibility. 1st European Medical Students’ Symposium, Athens, Greece, 15 to 16-4-1995.

Supervision

	Thesis Title Role	Degree Subject (Type) Institution / Organization
2021 - Current	Genetic and Functional Studies of Growth Hormone Deficiency Supervisor	PhD Biomedicine (PhD) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2020 - Current	Identification of new genetic causes of congenital hypogonadotropic hypogonadism using next-generation sequencing Supervisor	PhD Biomedicine (PhD) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2020 - Current	Genetic risk factors for pituitary adenomas: a national, multicenter, genetic and clinical analysis Supervisor	PhD Biomedicine (PhD) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2022 - 2022	Maternal-fetal impact of pharmacological treatment of prolactinomas Supervisor	Medicine (Master) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2017 - 2022	Intraoperative identification of parathyroid glands using near-infrared fluorescence. Co-supervisor	PhD Medicine (PhD) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2021 - 2021	Efficacy of negative pressure therapy in diabetic foot disease Supervisor	Medicine (Master) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2021 - 2021	Clinical utility of oxytocin in apetite and obesity Supervisor	Medicine (Master) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2019 - 2019	Outcomes of subclinical hypothyroidism in pregnancy and it treatment Supervisor	Medicine (Master) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2019 - 2019	Effect of intermittent fasting in type 2 diabetes Supervisor	Medicine (Master) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2019 - 2019	Clinical and cognitive characterization of institutionalized elderly people with type 2 diabetes Co-supervisor	Medicine (Master) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2019 - 2019	Risk factors for postpartum thyroiditis Supervisor	Medicine (Master) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2018 - 2018	Immunosuppressive approaches for the preservation of beta cells in type 1 diabetes Supervisor	Medicine (Master) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2018 - 2018	Genetic susceptibility to thyroid cancer: genomic variants in the vitamin D pathway. MSc. Thesis (Biochemistry): University of Beira Interior, 2018. Supervisor	Biochemistry (Master) Universidade da Beira Interior Faculdade de Ciências, Portugal
2017 - 2017	Genetic susceptibility to type 1 diabetes: genomic variants in the vitamin D pathway Supervisor	Biochemistry (Master) Universidade da Beira Interior Faculdade de Ciências, Portugal
2017 - 2017	Association between type 2 diabetes and Parkinson's disease Supervisor	Medicine (Master) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2017 - 2017	Natural antioxidants in type 2 diabetes and complications Supervisor	Medicine (Master) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2017 - 2017	Clinical and molecular characterisation of a case of Hypoparathyroidism, Deafness & Renal Dysplasia Syndrome Supervisor	Medicine (Master) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2016 - 2016	Genetic and epigenetic mechanisms involved in regulation of STEAP1 gene expression in LNCaP prostate cancer cells Co-supervisor	Biochemistry (Master) Universidade da Beira Interior Faculdade de Ciências, Portugal
2012 - 2016	Molecular Genetics of Congenital Hypogonadotropic Hypogonadism Supervisor	Biomedicine (PhD) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2015 - 2015	Metformin and Cancer: what is the relation? Supervisor	Medicine (Master) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2015 - 2015	Genetic susceptibility to thyroid cancer: effect of polymorphisms of the FOXE1 gene Supervisor	Biochemistry (Master) Universidade da Beira Interior Faculdade de Ciências, Portugal
2015 - 2015	Anabolic steroids abuse and psychiatric disorders Supervisor	Medicine (Master) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2014 - 2014	Testosterone: possible protective effect against cardiovascular events in men Supervisor	Medicine (Master) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2014 - 2014	Clinical and molecular characterisation of a case of familial hypercholesterolemia Supervisor	Medicine (Master) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2014 - 2014	Thyroid autoantibodies and risk of recurrent spontaneous abortion Supervisor	Medicine (Master) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2014 - 2014	Subclinical hypothyroidism and acute myocardial infarction: what is the relation? Supervisor	Medicine (Master) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2014 - 2014	Identification of a novel mutation in androgen insensitivity syndrome Supervisor	Medicine (Master) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2014 - 2014	Prevalence of thyroid cancer in patients with acromegaly Supervisor	Medicine (Master) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2014 - 2014	Graves ophtalmopathy and quality of life after treatment Supervisor	Medicine (Master) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2013 - 2013	Vitamin D receptor (VDR) gene polymorphisms and genetic susceptibility to thyroid cancer Supervisor	Ciências Biomédicas (Master) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2013 - 2013	Migraine and serum levels of prolactin Co-supervisor	Medicine (Master) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2013 - 2013	Prediabetes and risk of stroke Supervisor	Medicine (Master) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2013 - 2013	Eating disorders in type 1 diabetes Supervisor	Medicine (Master) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2012 - 2012	Neuropsychiatric manifestations in Cushing's Syndrome Supervisor	Medicine (Master) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2012 - 2012	Comparison of combined T4/T3 therapy and monotherapy in the treatment of hypothyroidism. MSc. Thesis: University of Beira Interior, 2012. Supervisor	Medicine (Master) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2012 - 2012	Metabolic surgery in type 2 diabetes: efficacy of different surgical procedures and comparison of patients with BMI under and over 35 kg/m2 Supervisor	Medicine (Master) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2012 - 2012	Identification of genetic mutations in patients with familial central diabetes insipidus Supervisor	Biochemistry (Master) Universidade da Beira Interior Faculdade de Ciências, Portugal
2012 - 2012	Genetic susceptibility to thyroid cancer: contributions of RET polymorphisms. Supervisor	Biomedical Sciences (Master) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2012 - 2012	Growth hormone receptor exon 3 polymorphisms: prevalence, genotype-phenotype relationship and effect on growth hormone treatment response Supervisor	Pharmaceutical Sciences (Master) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2011 - 2011	The importance of the thyroid in mental disorders Supervisor	Medicine (Master) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2010 - 2010	Vitamin D and type 1 diabetes Supervisor	Medicine (Master) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2009 - 2009	Genetics of familial pheochromocytomas and paragangliomas Supervisor	Medicine (Master) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2009 - 2009	Variation of glycaemia after sublingual administration of sacharose: implications for the pre-hospital treatment of hypoglycaemia Supervisor	Medicine (Master) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2008 - 2008	New approaches to insulin therapy: Continuous subcutaneous insulin infusion Supervisor	Medicine (Master) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal

Event participation

	Activity description Type of event	Event name Institution / Organization
2014 - 2014	Conference Poster: Machado A, Oliveira MJ, Borges T, Cardoso H, Fonseca P, Ribeiro L, Gonçalves C, Lemos MC. Kallmann Syndrome: Diagnosis in Paediatric Age. 53rd Meeting of the European Society for Paediatric Endocrinology, Dublin, Ireland, 19-9-2014.
2013 - 2013	Conference Poster: Azevedo TC, Rodrigues FJ, Martins TM, Neto J, Rovira E, Lemos MC, Martinho M, Oliveira S. Low-risk papillary thyroid carcinoma: to ablate or not to ablate. 37h Annual Meeting of the European Thyroid Association, Leiden, The Netherlands, September 7 to 11-9-2013.
2009 - 2009	Conference Poster: Martinho M, Martins TD, Azevedo T, Prazeres H, Martins TC, Cruz C, Neves A, Bugalho MJ, Lemos MC, Carrilho F, Carvalheiro M, Campos B, Rodrigues F. Phenotypic characterization of a RET proto-oncogene mutation with distinct distribution in the central region of Portugal in Multiple Endocrine Neoplasia type 2A. 34th Annual Meeting of the European Thyroid Association, Lisbon, 5 to 9-9-2009.
2008 - 2008	Conference Poster: Lemos MC, Harding B, Reed A, Walls G, Tyler D, Bazan-Peregrino M, Ansorge O, Clarke K, Seymour L, Thakker RV. In vivo delivery of an adenoviral gene therapy vector to pituitary tumours in Men1 deficient mice. Society for Endocrinology British Endocrine Societies 2008; Harrogate, UK, 7 to 10-4-2008. (Awarded best poster prize)
2008 - 2008	Conference Poster: Lemos MC, Bazan-Peregrino M, Harding B, Seymour L, Thakker RV. Construction of a recombinant adenovirus vector for Men1 gene delivery. Society for Endocrinology British Endocrine Societies 2008; Harrogate, UK, 7 to 10-4-2008.
2007 - 2007	Conference Poster: Lemos MC, Harding B, Thakker RV. 2007. Genetic background influences expression of Multiple Endocrine Neoplasia type 1 (MEN1) mutation, implicating a role for genetic modifiers. UK and Ireland Neuroendocrine Tumour Society (UKI NETS) 5th National Conference, The Royal Society of Medicine, London, UK, 3-12-2007. (Awarded best poster prize)
2007 - 2007	Conference Poster: Harding B, Lemos MC, Shalet SM, Thakker RV. Multiple Endocrine Neoplasia Type 1 (MEN1) caused by a novel mutation in intron 9 in a family with the McCune-Albright syndrome. Society for Endocrinology BES 2007, Birmingham, UK, 5 to 8-3-2007.
2007 - 2007	Conference Poster: Lemos MC, Harding B, Thakker RV. Genetic background influences expression of Multiple Endocrine Neoplasia type 1 (MEN1) mutation, implicating a role for genetic modifiers. Society for Endocrinology BES 2007, Birmingham, UK, 5 to 8-3-2007.
2003 - 2003	Conference Poster: Baptista C, Bastos M, Leitão F, Ribeiro H, Alves R, Bastos C, Leitão P, Lemos MC, Campos MV, Mota A, Furtado L, Carvalheiro M. Kidney post-transplant diabetes: autoantibodies and beta-cell function. 18th International Diabetes Federation Congress, Paris, France, 24 to 28-8-2003.
2003 - 2003	Conference Poster: Gomes L, Lemos MC, Leitão P, Campos MV, Carrilho F, Geraldes E, Carvalheiro M. Type 1 diabetes autoantibodies in patients diagnosed as type 2 diabetes mellitus: prevalence and correlation with clinical parameters. 18th International Diabetes Federation Congress, Paris, France, 24 to 28-8-2003.
2003 - 2003	Conference Poster: Campos MV, Donato P, Bastos M, Leitão P, Lemos MC, Carrilho F, Carvalheiro M. Carotid intima-media thickness in childhood-onset growth hormone deficiency. 6th European Congress of Endocrinology, Lyon, France, 26 to 30-4-2003.
2003 - 2003	Conference Poster: Bastos M, Baptista C, Leitão F, Ribeiro H, Alves F, Bastos C, Leitão P, Lemos MC, Campos M, Mota A, Furtado L, Carvalheiro M. Kidney post transplant diabetes: auto antibodies and beta cell function. 6th European Congress of Endocrinology, Lyon, France, de 26 a 30-4-2003.
2003 - 2003	Conference Poster: Fagulha A, Barros L, Leitão P, Lemos MC, Campos MV, Carrilho F, Carvalheiro M. Risk factors of microangiopathy in type 1 diabetes of short and long duration in late adolescence. 6th European Congress of Endocrinology, Lyon, France, 26 to 30-4-2003.
2003 - 2003	Conference Poster: Martins T, Carrilho F, Leitão P, Lemos MC, Campos M, Geraldes E, Carvalheiro M. Anaplastic thyroid cancer: retrospective analysis of 12 clinical cases. 6th European Congress of Endocrinology, Lyon, France, 26 to 30-4-2003.
2003 - 2003	Conference Poster: Carrilho F, Martins T, Leitão P, Lemos MC, Campos M, Geraldes E, Carvalheiro M. Recombinante human TSH stimulated thyroglobulin levels in the post surgical follow up of five patients with papillary thyroid carcinoma. 6th European Congress of Endocrinology, Lyon, France, 26 to 30-4-2003.
2002 - 2002	Conference Poster: Paiva I, Ribeiro C, Baptista C, Martins T, Leitão P, Campos MV, Lemos MC, Geraldes E, Carvalheiro M. Type 2 diabetes in persons older than 80 years. Evaluation of quality of care in a subset of patients hospitalised from 1990 to 2001. 38th Annual Meeting of the European Association for the Study of Diabetes, Budapest, Hungary, 1 to 5-9-2002.
2002 - 2002	Conference Poster: Gomes L, Lemos MC, Paiva I, Ribeiro C, Carvalheiro M, Regateiro FJ. Cytochrome P450 2D6 gene (CYP2D6) polymorphisms and susceptibility to pituitary tumours. 10th Meeting of the European Neuroendocrine Association, Munich, Germany, 12 to 14-9-2002.
2002 - 2002	Conference Poster: Lemos MC, Gomes L, Bastos M, Regateiro FJ, Carvalheiro M. Screening of PROP1 gene mutations in familial and sporadic combined pituitary hormone deficiency. 10th Meeting of the European Neuroendocrine Association, Munich, Germany, 12 to 14-9-2002.
2002 - 2002	Conference Poster: Lemos MC, Fagulha A, Ruas L, Christie PT, Thakker RV, Carvalheiro M. Pseudohypoparathyroidism type IA due to a novel mutation in GNAS1 gene. Endocrine Society’s 84th Annual Meeting, San Francisco, California, USA, 19 to 22-6-2002.
2002 - 2002	Conference Poster: Lemos MC, Rodrigues D, Gomes L, Christie PT, Thakker RV, Carvalheiro M. A novel AVPR2 mutation in a kindred with nephrogenic diabetes insipidus. 34th Annual Meeting of the European Society of Human Genetics, Strasburg, France, 25 to 29-5-2002.
2002 - 2002	Conference Poster: Bacelar C, Monteiro M, Vargas G, Lemos MC, Regateiro F, Carvalheiro M, Ramos H. Familial combined pituitary hormone deficiency by PROP1 gene mutation in a Portuguese family. 21st Joint Meeting of the British Endocrine Societies, Harrogate, United Kingdom, 8 to 11-4-2002.
2002 - 2002	Conference Poster: Lemos MC, Christie PT, Harding B, Kotanko P, Thakker RV, Javor T. Hereditary multiple exostosis due to an acceptor splice site mutation in the EXT1 gene. 21st Joint Meeting of the British Endocrine Societies, Harrogate, United Kngdom, 8 to 11-4-2002.
2001 - 2001	Conference Poster: Carrilho F, Rodrigues F, Paiva I, Lemos MC, Gomes L, Ribeiro C, Ruas L, Rodrigues D, Barros L, Paiva S, Baptista C, Fagulha A, Bastos M, Geraldes E, Carvalheiro M, Ruas MMA. Medullary thyroid carcinoma: diagnosis, treatment and follow-up of 13 patients. 5th European Congress of Endocrinology, Turin, Italy, 9 to 13-6-2001.
2001 - 2001	Conference Poster: Ruas L, Rodrigues F, Baptista C, Martins T, Leitão P, Lemos MC, Campos MV, Neto J, Moreira AP, Oliveira S, Lima PJ, Carvalheiro M, Ruas MMA. Treatment with 131I of toxic multinodular goiter and toxic adenoma - results at 3 years. 5th European Congress of Endocrinology, Turin, Italy, 9 to 13-6-2001.
2001 - 2001	Conference Poster: Rodrigues FJC, Ruas L, Neto J, Lemos MC, Moreira AP, Oliveira S, Martins T, Leitão P, Campos MV, Lima PJ, Carvalheiro M, Ruas MMA. Radioiodine treatment of Graves’ hyperthyroidism. 5th European Congress of Endocrinology, Turin, Italy, 9 to 13-6-2001.
2001 - 2001	Conference Poster: Paiva I, Ribeiro C, Martins T, Leitão P, Lemos MC, Campos MV, Carvalheiro M, Ruas MMA. Octreotide and cardiovascular risk factors in acromegaly. 5th European Congress of Endocrinology, Turin, Italy, 9 to 13-6-2001.
2001 - 2001	Conference Poster: Gomes L, Ribeiro C, Paiva I, Gomes F, Rito M, Rebelo O, Martins T, Leitão P, Lemos MC, Campos MV, Carvalheiro M, Ruas MMA. Clinically non-functioning pituitary macroadenomas: a review of 100 cases. 5th European Congress of Endocrinology, Turin, Italy, 9 to 13-6-2001.
2001 - 2001	Conference Poster: Lemos MC, Bastos M, Martins T, Leitão P, Campos MV, Carvalheiro M, Ruas MMA. Final height after growth hormone therapy in a group of Portuguese children with Turner syndrome. 5th European Congress of Endocrinology, Turin, Italy, 9 to 13-6-2001.
2001 - 2001	Conference Poster: Rodrigues D, Bastos M, Martins T, Leitão P, Lemos MC, Campos MV, Carvalheiro M, Ruas MMA. Adrenal incidentalomas - a review of 43 cases. 5th European Congress of Endocrinology, Turin, Italy, 9 to 13-6-2001.
2001 - 2001	Conference Poster: Campos MV, Bastos M, Lemos MC, Leitão P, Martins T, Carvalheiro M, Ruas MMA. Diabetic hyperosmolality: retrospective study of 60 cases. 5th European Congress of Endocrinology, Turin, Italy, 9 to 13-6-2001.
1999 - 1999	Conference Poster: Lemos MC, Alexandrino MB, Plácido F, Regateiro FJ. Overrepresentation of the NAT2*5B allele in multiple myeloma patients. 31th Annual Meeting of the European Society of Human Genetics, Geneva, Switzerland, 29-5 to 1-6-1999.
1999 - 1999	Conference Poster: Coimbra H, Lemos MC, Brêda MM, Purificação A, Lima L, Regateiro F. CYP2D6, GSTM1 and NAT2 polymorphisms in a Portuguese glioblastoma population. 7th CEPH Annual Conference on Human Genetics, Paris, France, 26 to 28-5-1999.
1998 - 1998	Conference Poster: Lemos MC, Regateiro FJ. Relationship between polymorphism at the CYP2D6 locus and susceptibility to haematological neoplasias. 30th Annual Meeting of the European Society of Human Genetics, Lisbon, Portugal, 10 to 13-5-1998.

Course / Discipline taught

	Academic session	Degree Subject (Type)	Institution / Organization
2011 - Current	Research Methodology	Medicina (PhD Medicine) (Doutoramento)	Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2010 - Current	Scientific Communication	Medicina (PhD Medicine) (Doutoramento)	Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2010 - Current	Thesis Project	Medicina (PhD Medicine) (Doutoramento)	Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2008 - Current	Pathophysiology and Pharmacology	Ciências Farmacêuticas (MSc Pharmaceutical Sciences) (Mestrado integrado)	Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2005 - Current	Endocrinology	Medicina (Medicine) (Mestrado integrado)	Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
1996 - 2006	Medical Genetics	Medicina (Medicine) (Licenciatura)	Universidade de Coimbra Faculdade de Medicina, Portugal

Distinctions

Award

2023	1st Prize for Best Clinical Series (AIP gene mutations in portuguese patients with young onset sporadic pituitary macroadenomas) (74th Annual Meeting of the Portuguese Society for Endocrinology, Diabetes and Metabolism) Sociedade Portuguesa de Endocrinologia Diabetes e Metabolismo, Portugal
2016	2nd Prize for Best Clinical Series (Genetic characterisation of 202 cases of growth homone deficiency) (67th Annual Meeting of the Portuguese Society for Endocrinology, Diabetes and Metabolism) Sociedade Portuguesa de Endocrinologia, Diabetes e Metabolismo, Portugal
2015	3rd Prize for Best Clinical Case (Identification of a new mutation associated with the androgen insensitivity syndrome) (66th Annual Meeting of the Portuguese Society for Endocrinology, Diabetes and Metabolism) Sociedade Portuguesa de Endocrinologia, Diabetes e Metabolismo, Portugal
2015	Award for Best Clinical Series (Hypogonadotrophic hypogonadism: identification of 6 new mutations in the FGFR1 gene) (66th Annual Meeting of the Portuguese Society for Endocrinology, Diabetes and Metabolism) Sociedade Portuguesa de Endocrinologia, Diabetes e Metabolismo, Portugal
2015	National Award in Endocrinology (Genetic suceptibility to thyroid cancer: the role of vitamin D receptor polymorphisms) Sociedade Portuguesa de Endocrinologia, Diabetes e Metabolismo, Portugal
2014	Award for best clinical case report - Familial central diabetes insipidus: clinical characterisation and identification of a novel mutation in the vasopressin gene. (65th Annual Meeting of the Portuguese Society for Endocrinology, Diabetes and Metabolism) Sociedade Portuguesa de Endocrinologia, Diabetes e Metabolismo, Portugal
2011	Scientific Merit Award (Prémio de Mérito Científico UBI-FCS / Santander Universidades) Universidade da Beira Interior, Portugal Banco Santander Totta, Portugal
2008	Best Poster Award - "In vivo delivery of an adenoviral gene therapy vector to pituitary tumours in Men1 deficient mice" (Society for Endocrinology BES 2008 meeting, UK) Society for Endocrinology, United Kingdom
2007	Young Endocrinologist Award (Society for Endocrinology BES 2007 meeting, UK) Society for Endocrinology, United Kingdom
2007	Best Poster Award - "Genetic background influences expression of Multiple Endocrine Neoplasia type 1 (MEN1) mutation, implicating a role for genetic modifiers", UK and Ireland Neuroendocrine Tumour Society (UKI NETS) 5th National Conference
2004	SPD/Novartis Award (Prémio Hargreaves) for Best Research Project in Diabetes - "Genetic susceptibility to type 1 diabetes: effect of polymorphisms of the VDR and CTLA4 genes" Sociedade Portuguesa de Diabetologia, Portugal
2004	Junior Research Fellowship, Wolfson College, University of Oxford University of Oxford Wolfson College, United Kingdom
2002	1st Prize in Basic Research - “Identification of a novel mutation in the vasopressin-neurophysin II gene in a family with central diabetes insipidus" (53º Annual Meeting of the Portuguese Society for Endocrinology, Diabetes and Metabolism) Sociedade Portuguesa de Endocrinologia, Diabetes e Metabolismo, Portugal
2002	1st Prize for Best Research Project by Medical Interns - "Molecular and clinical characterisation of a family with MEN2A: implications for early diagnosis" Fundação Bissaya Barreto, Portugal
2002	2nd Prize for Best Research Project in Diabetes (Prémio Ernesto Roma / Roche Diagnostics) - "NAT2 polymorphisms and susceptibility to type 1 diabetes" Associacao Protectora dos Diabeticos de Portugal, Portugal
1999	Pfizer Award for Young Scientists (2nd place), Sociedade das Ciências Médicas de Lisboa
1995	2nd Prize for Best Research by Medical - “Genetic alterations induced by tobacco smoke and cytostatics", Portuguese Medical Students Association
1995	Young Investigator Award (Programa Gulbenkian de Estímulo à Investigação) Fundação Calouste Gulbenkian, Portugal
1994	1st Prize for Best Research by Medical Students - “Genetic polymorphism of CYP2D6 and susceptibility to cancer”, Portuguese Medical Students Association