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Miguel M. Santos received his PhD in chemistry in 2013 by the University of Aveiro on the molecular recognition of inorganic and organic anions by amide- and urea-containing azacalix[2]arene[2]triazines and isoftalamides. Since March 2015 he is a researcher at LAQV-REQUIMTE and NOVA School of Sciences and Technology focusing on the synthesis and characterization of novel Ionic Systems and biopolymers for pharmaceutical and health applications. He is currently a Junior researcher under the scope of the project "Active Pharmaceutical Ionic Liquids as new platform for Effective Treatment of Tuberculosis (TB-ILs)¿ Ref. PTDC/QUI-QOR/32406/2017, on which he develops novel ionic formulations of antitubercular drugs with enhanced bioavailability and therapeutic activity. He published 18 papers in international peer-reviewed journals and 3 book chapters (h-index: 11; citations: 255 - Google Scholar). His work was the subject of 13 oral presentations and 20 posters at international and national conferences. He has co-organized one national and one international conferences. He is guest editor of the Pharmaceutics Special Issue s"Ionic Liquids and Deep Eutectic Solvents for Application in Pharmaceutics(Vols. I & II)" and "Therapeutic Formulations of Repurposed Drugs against COVID-19". He has peer-reviewed papers for Nanomaterials, Pharmaceutics, Metals, Sustainable Chemistry, ACS Infectious Diseases, Molecules, Biomaterials, PLOS One and International Journal of Molecular Sciences. He is also topic editor at MDPI and editorial board member of Int. J. Pharm. Chem.(SPG). He is the Principal Investigator of 1 funded ongoing project (ILs4Treatment - 'Repurposed antimalarial and anti-Ebola drugs as Organic Salts and Ionic Liquids to prevent and fight COVID-19' RESEARCH4COVID-19 2ª edição n. 582) and 3 other projects as Researcher. His pedagogical skills include supervision of 10 BSc, 5 MSc and 2 PhD thesis, as well as classes in Applied Chemistry and General and Inorganic Chemistry at Lisbon Polytechnic School of Health Technologies as Invited Professor.
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Identification

Personal identification

Full name
Miguel Maurício Machado dos Santos

Citation names

  • Santos, Miguel
  • Miguel M. Santos

Author identifiers

Ciência ID
4C1A-CA63-AD4F
ORCID iD
0000-0001-8973-1595

Knowledge fields

  • Exact Sciences - Chemical Sciences - Organic Chemistry
  • Natural sciences - Biological Sciences - Biochemistry

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Spanish; Castilian Intermediate (B1) Intermediate (B1) Intermediate (B1) Intermediate (B1)
Education
Degree Classification
2009/01/01 - 2013/10/03
Concluded
 PhD Program in Chemistry (Doutoramento)
Major in Supramolecular Chemistry
Universidade de Aveiro, Portugal
"Anion receptors based on azacalix[4]arenes and isoftalamides" (THESIS/DISSERTATION)
 Approved
2010/07/06 - 2010/07/10
Concluded
 HPLC - HPLC: from fundamentals to application (Curso de Especialização Tecnológica)
Universidade do Porto Faculdade de Farmácia, Portugal
2010/06/14 - 2010/06/17
Concluded
 3rd CERMAX practical course on basic NMR (Curso de Especialização Tecnológica)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2010/05/15 - 2010/05/18
Concluded
 Hands on course on ligand based NMR interaction studies (Curso de Especialização Tecnológica)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2009/07/07 - 2009/07/10
Concluded
 Medicinal Chemistry – medicinal chemistry and drug planning (Curso de Especialização Tecnológica)
Universidade do Porto Faculdade de Farmácia, Portugal
2008
Concluded
 Chemistry (Chemistry, Health and Nutrition) (Mestrado)
Universidade de Lisboa Faculdade de Ciências, Portugal
"HY zeolite-mediated phenol glycosilation" (THESIS/DISSERTATION)
 19/20
2006/10/06
Concluded
 Chemistry (Licenciatura)
Universidade de Lisboa Faculdade de Ciências, Portugal
"Synthesis and protease inhibition of carbamates and sulfenamides" (THESIS/DISSERTATION)
 15/20
Affiliation

Science

Category
Host institution 		Employer
2019/03/15 - 2022/03/14 Contracted Researcher (Research) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
(...)

Teaching in Higher Education

Category
Host institution 		Employer
2021/10/01 - 2022/02/28 Invited Adjunct Teacher (Polytechnic Teacher) Instituto Politécnico de Lisboa Escola Superior de Tecnologia da Saúde de Lisboa, Portugal
Instituto Politécnico de Lisboa Escola Superior de Tecnologia da Saúde de Lisboa, Portugal
2020/09/15 - 2021/02/14 Invited Adjunct Teacher (Polytechnic Teacher) Instituto Politécnico de Lisboa Escola Superior de Tecnologia da Saúde de Lisboa, Portugal
Instituto Politécnico de Lisboa Escola Superior de Tecnologia da Saúde de Lisboa, Portugal
2019/09/15 - 2020/02/14 Invited Adjunct Teacher (Polytechnic Teacher) Instituto Politécnico de Lisboa Escola Superior de Tecnologia da Saúde de Lisboa, Portugal
Instituto Politécnico de Lisboa Escola Superior de Tecnologia da Saúde de Lisboa, Portugal

Others

Category
Host institution 		Employer
2017/02/06 - 2019/04/30 Post-doc fellow under the scope of the SunStorage project (03/SAICT/2015 - 016387) - Vanadium Ionic Liquid-based electrolytes for Redox Flow Batteries. Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
2016/06/02 - 2017/02/05 Post-Doc fellow under the scope of FEUP's internal project - Innovative vanadium Ionic Liquid-based electrolytes for Redox Flow Batteries. Universidade do Porto Laboratorio de Engenharia de Processos Ambiente Biotecnologia e Energia, Portugal
2015/03/01 - 2016/06/01 Post-Doc fellow CQFB/REQUIMTE/BI/004/2015 under the scope of the project IF/0041/2013/CP1161/CT005. Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
2013/11/11 - 2014/12/31 Post-Doc fellow QREN-ADI 13857_BI_1_2013 under the scope of the Ynvisible Network project (QREN-ADI 13857) Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
2009/02/01 - 2013/10/03 PhD fellow SFRH/BD/48490/2008 Universidade de Aveiro CICECO, Portugal
2008/08/01 - 2008/12/31 MSc fellow - synthesis of carbohydrates with insecticide activity for Novartis Universidade de Lisboa Centro de Química e Bioquímica, Portugal
2007/10/01 - 2008/07/31 MSc thesis Universidade de Lisboa Faculdade de Ciências, Portugal
2007/08/01 - 2007/09/30 Internship Universidade de Lisboa Centro de Química e Bioquímica, Portugal
2006/11/28 - 2007/05/31 Fellowship under the scope of Leonardo da Vinci European Mobility Program Universidad de Extremadura Departamento de Química Orgánica e Inorgánica, Spain
2005/10/01 - 2006/10/01 BSc thesis Universidade de Lisboa Faculdade de Ciências, Portugal
Projects

Grant

Designation Funders
2015/03 - 2016/02 IF/0041/2013/CP1161/CT005
REQUIMTE/BI/004/2015
 Ministério da Ciência Tecnologia e Ensino Superior
2013/11 - 2014/12 Invisible Network - Desenvolvimento de novos produtos, processos e sistemas para a indústria da computação invisível
QREN-ADI 13857_BI_1_2013
 Ministério da Educação
2010/06 - 2013/12 Development of azacalix(hetero)arene transporters for mediated anionic flux across membranes: a novel approach for studying ionic passive diffusion
101022
Provided by PTCRIS: 101022
 Fundação para a Ciência e a Tecnologia, I.P.

Contract

Designation Funders
2018/09/15 - 2020/12/14 Active Pharmaceutical Ionic Liquids as new platform for Effective Treatment of Tuberculosis
PTDC/QUI-QOR/32406/2017
Researcher
Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
Ongoing
2017/06/02 - 2019/03/14 Sunstorage - Recolha e armazenamento de energia
03/SAICT/2015 - 016387
Post-doc Fellow
Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
Concluded

Other

Designation Funders
2020/07/06 - 2021/04/05 ILs4Treatment - Repurposed antimalarial and anti-Ebola drugs as Organic Salts and Ionic Liquids to prevent and fight COVID-19
582
Principal investigator
Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
 Associação para a Inovação e Desenvolvimento da FCT
Ongoing
Outputs

Publications

Book chapter
  1. Miguel M. Santos; Luis C. Branco; Karolina Zalewska. "Asymmetric organocatalysis in alternative media". edited by Ana Phillips. 2021.
    Submitted
  2. Luis C. Branco; Karolina Zalewska; Miguel M. Santos. "Sustainable synthetic approaches for nitrogen-containing heterocyclic salts". In Synthetic Approaches to Nonaromatic Nitrogen Heterocycles, 2 Volume Set, edited by Ana Phillips, 729-765. Wiley, 2020.
    Published
  3. Victória Inês Patrício Paz; Karolina Zalewska Patrício; Miguel Santos; Luis C Branco. "Sustainable Synthetic Approaches for Nitrogen-Containing Heterocyclic Salts". edited by Phillips, {Ana Maria M. M. Faisca. Wiley, 2020.
    10.1002/9781119708841.ch23
  4. Zalewska, Karolina; Santos, Miguel M.; Cruz, Hugo; Branco, Luis C.. "Photo-Organocatalysis, Photo-Redox, and Electro- Organocatalysis Processes". In Recent Advances in Organocatalysis, edited by Iyad Karamé, 109-137. InTech, 2016.
    Published • 10.5772/64633
  5. Rauter, Amélia P.; Xavier, Nuno M.; Lucas, Susana D.; Santos, Miguel. "Zeolites and Other Silicon-Based Promoters in Carbohydrate Chemistry". In Advances in Carbohydrate Chemistry and Biochemistry, edited by Derek Horton, 29-99. Elsevier, 2010.
    Published • 10.1016/s0065-2318(10)63003-x
Conference abstract
  1. Miguel M. Santos. "Z. Petrovski, M. M. Santos, I. R. Grilo, L. Pinheiro, R. Sobral, R. Ferraz, C. Prudêncio, L. C. Branco, "Ionic Liquids Derived from ß-Lactam Antibiotics Against Resistant Bacteria"". Paper presented in IC2AR 2019, 3rd International Caparica Congress in Antibiotic Resistance, Caparica, 2019.
    Published
Conference poster
  1. Miguel M. Santos. "M. M. Santos, I. R. Grilo, N. Inácio, L. Pinheiro, Z. Petrovski, R. Sobral, R. Ferraz, C. Prudêncio, L. C. Branco, "Antimicrobial Activity of Organic Salts and Ionic Liquids"". Paper presented in 1st Greenering International Conference online, 2021.
  2. Miguel M. Santos. "M. M. Santos, D. Madeira, A. Costa, C. Alves, R. Pedrosa, L.C. Branco, "Fluoroquinolone-based Organic Salts and Ionic Liquids as Highly Bioavailable Broad-Spectrum Antimicrobials"". Paper presented in First International Electronic Conference on Pharmaceutics, 2020.
  3. Miguel M. Santos. "M. M. Santos, I. R. Grilo, N. Inácio, L. Pinheiro, Z. Petrovski, R. Sobral, R. Ferraz, C. Prudêncio, L. C. Branco, "Antibacterial Activity Against Sensitive and Resistant bacteria of Organic salts and Ionic Liquids based on ß-lactam Antibiotics and Their Hydrolysates"". Paper presented in 6th International Electronic Conference on Medicinal Chemistry, 2020.
  4. Miguel M. Santos. "Z. Petrovski, M. M. Santos, A. Costa, C. Alves, R. Pedrosa, L. Pinheiro, R. Ferraz, C. Prudêncio, L. C. Branco, "Enhanced antimicrobial activity of Organic Salts and Ionic Liquids derived from antibiotics"". Paper presented in III-International- Conference-NOVAhealth-Chronic-Disease-and-Infection (online), 2020.
  5. Miguel M. Santos. "M. M. Santos, I. R. Grilo, R. Ferraz, D. A. Madeira, B. M. Soares, N. Inácio, L. Pinheiro, Z. Petrovski, C. Prudêncio, R. G. Sobral, L. C. Branco, "Tackling bacterial resistance using antibiotics as Ionic Liquids and Organic Salts"". Paper presented in MicroBioTec19, 2019.
  6. Miguel M. Santos. "Z. Petrovski, M. M. Santos, I. R. Grilo, N. Inácio, L. Pinheiro, R. Sobral, R. Ferraz, C. Prudêncio, L. C. Branco, "Tackling bacterial resistance using antibiotics as ionic liquids and organic salts"". Paper presented in 5th International Electronic Conference on Medicinal Chemistry, 2019.
  7. Miguel M. Santos. "M. M. Santos, I. R. Grilo, S. Teixeira, L. R. Raposo, N. Inácio, L. Pinheiro, Z. Petrovski, R. Sobral, M. H. Fernandes, J. C. Rodrigues, A. R. Fernandes, P. V. Batista, L. C. Branco, "Ionic Liquids and Organic Salts from Active Pharmaceutical Ingredients"". Paper presented in XXVI ENSPQ, 2019.
  8. Miguel M. Santos. "D. Silva, M. M. Santos, I. R. Grilo, L. Pinheiro, Z. Petrovski, R. Sobral, L. C. Branco, "Meropenem-based Ionic Liquids and Salts as anti-microbial agents"". Paper presented in XXV Encontro Nacional SPQ, 2019.
  9. Miguel M. Santos. "M. M. Santos, I. R. Grilo, L. Pinheiro, Z. Petrovski, R. Sobral, R. Ferraz, C. Prudêncio, L. C. Branco, "Antimicrobial Ionic Liquids: synthesis and anti-bacterial activities"". Paper presented in 6th Portuguese Young Chemist Meeting (6th PYCheM), 2018.
  10. Miguel M. Santos. "M. M. Santos, L. Pinheiro, D. Landum, R. Ferraz, Z. Petrovski, J. P. Noronha, C. Prudêncio, L. C. Branco, "Ionic Liquids and Salts of Antibiotic and Antiviral Drugs"". Paper presented in XXV ENSPQ, 2017.
  11. Miguel M. Santos. "M. M. Santos, H. Cruz, L. C. Branco, A. Mendes, "Innovative electrolytes based on ionic liquids for vanadium redox flow batteries"". Paper presented in Hyceltec 2017, 2017.
  12. Miguel M. Santos. "M. M. Santos, A. Costa, A. Forte, M. Dionísio, L. C. Branco, "Ibuprofen and Naproxen Ionic Liquids: Old Drugs, New Properties"". Paper presented in 19ESOC, 2015.
  13. Miguel M. Santos. "D. Batista, A. Assunção, A. R. Jesus, M. M. Santos, A. P. Carvalho, A. P. Rauter, "Phenols Glycosylation Promoted by Zeolites"". Paper presented in CQB Day, 2014.
  14. Miguel M. Santos. "T. Esteves, J. M. Caio, M. M. Santos, A. I. Vicente, C. Moiteiro, S. Carvalho, V. Félix, "Functionalized azacalix[2larene[2]triazines for the recognition of biologically relevant anions"". Paper presented in XXIII ENSPQ, 2013.
  15. Miguel M. Santos. "M. M. Santos, C. Moiteiro, V. Félix, "Molecular Recognition of Biologically Relevant Anions by Chiral Tetraazacalix[2]arene[2]triazine Receptors"". Paper presented in 13th Belgium Organic Synthesis Symposium, 2012.
  16. Miguel M. Santos. "M. M. Santos, C. Moiteiro, V. Félix, "Molecular Recognition of Biologically Relevant Anions by Chiral Tetraazacalix[2]arene[2]triazine Receptors"". Paper presented in 6th SPJOCS, 2012.
  17. Miguel M. Santos. "M. M. Santos, A. R. Jesus, S. D. Lucas, A. P. Carvalho, J. P. Marques, M. Guisnet, F. Ramôa-Ribeiro, A. P. Rauter, "Acid Zeolites as Environmental Benign Promoters for Carbohydrate Key Transformations"". Paper presented in 1st Portuguese Young Chemists Meeting, 2008.
  18. Miguel M. Santos. "P. Areces, E. Carrasco, J. Plumet, M. M. Santos, "1,2-Diacetals as Chiral Templates for the Synthesis of ß-Lactams"". Paper presented in Glupor 7, 2007.
Journal article
  1. Dário Silva; Márcio V. C. Lopes; Željko Petrovski; Miguel M. Santos; Jussevania P. Santos; Sueli F. Yamada-Ogatta; Marcelle L. F. Bispo; et al. "Novel Organic Salts Based on Mefloquine: Synthesis, Solubility, Permeability, and In Vitro Activity against Mycobacterium tuberculosis". Molecules (2022): https://doi.org/10.3390/molecules27165167.
    Published • 10.3390/molecules27165167
  2. Francisco Faísca; Vanessa Correia; Željko Petrovski; Luís C. Branco; Helena Rebelo-de-Andrade; Miguel M. Santos. "Enhanced In Vitro Antiviral Activity of Hydroxychloroquine Ionic Liquids against SARS-CoV-2". Pharmaceutics 14 4 (2022): 877-877. https://doi.org/10.3390/pharmaceutics14040877.
    Published • 10.3390/pharmaceutics14040877
  3. Luis C. Branco; Miguel M. Santos; Karolina Zalewska. "Cyclodextrins in Room Temperature Ionic Liquids: dissolution, recovery and application studies". Physical Chemistry Chemical Physics (2022):
    Under revision
  4. Teixeira, Sónia; Santos, Miguel M.; Branco, Luís C.; Costa-Rodrigues, João. "Etidronate-based organic salts and ionic liquids: In vitro effects on bone metabolism". International Journal of Pharmaceutics 610 (2021): 121262. http://dx.doi.org/10.1016/j.ijpharm.2021.121262.
    Published • 10.1016/j.ijpharm.2021.121262
  5. Faísca, Francisco; Filipe, Luis; Petrovski, Zeljko; Santos, Miguel M.; Gago, Sandra; Branco, Luís C.. "Ionic Systems and Nanomaterials as Antiseptic and Disinfectant Agents for Surface Applications: A Review". Surfaces 4 2 (2021): 169-190. http://dx.doi.org/10.3390/surfaces4020016.
    Open access • Published • 10.3390/surfaces4020016
  6. Madeira, Diogo; Alves, Celso; Silva, Joana; Florindo, Catarina; Costa, Alexandra; Petrovski, Željko; Marrucho, Isabel M.; et al. "Fluoroquinolone-Based Organic Salts and Ionic Liquids as Highly Bioavailable Broad-Spectrum Antimicrobials". Proceedings 78 1 (2021): 3. http://dx.doi.org/10.3390/iecp2020-08649.
    Open access • Published • 10.3390/iecp2020-08649
  7. Blanca de Juan Mora; Luís Filipe; Andreia Forte; Miguel M. Santos; Celso Alves; Fernando Teodoro; Rui Pedrosa; et al. "Boosting Antimicrobial Activity of Ciprofloxacin by Functionalization of Mesoporous Silica Nanoparticles". Pharmaceutics 13 2 (2021): 218-218. https://doi.org/10.3390/pharmaceutics13020218.
    Open access • Published • 10.3390/pharmaceutics13020218
  8. Santos, Miguel M.; Branco, Luís C.. "Ionic Liquids and Deep Eutectic Solvents for Application in Pharmaceutics". Pharmaceutics 12 10 (2020): 909. http://dx.doi.org/10.3390/pharmaceutics12100909.
    Open access • Published • 10.3390/pharmaceutics12100909
  9. Moro, Artur J.; Santos, Miguel; Outis, Mani; Mateus, Pedro; Pereira, Pedro M.. "Selective Coordination of Cu2+ and Subsequent Anion Detection Based on a Naphthalimide-Triazine-(DPA)2 Chemosensor". Biosensors 10 9 (2020): 129. http://dx.doi.org/10.3390/bios10090129.
    Open access • Published • 10.3390/bios10090129
  10. Miguel M. Santos; Celso Alves; Joana Silva; Catarina Florindo; Alexandra Costa; Željko Petrovski; Isabel M. Marrucho; Rui Pedrosa; Luís C. Branco. "Antimicrobial Activities of Highly Bioavailable Organic Salts and Ionic Liquids from Fluoroquinolones". Pharmaceutics 12 8 (2020): 694-694. https://doi.org/10.3390/pharmaceutics12080694.
    Open access • Published • 10.3390/pharmaceutics12080694
  11. Sónia Teixeira; Miguel M. Santos; Maria H. Fernandes; João Costa-Rodrigues; Luís C. Branco. "Alendronic Acid as Ionic Liquid: New Perspective on Osteosarcoma". Pharmaceutics (2020): https://doi.org/10.3390/pharmaceutics12030293.
    10.3390/pharmaceutics12030293
  12. Ricardo Ferraz; Dário Silva; Ana Rita Dias; Vitorino Dias; Miguel M. Santos; Luís Pinheiro; Cristina Prudêncio; et al. "Synthesis and Antibacterial Activity of Ionic Liquids and Organic Salts Based on Penicillin G and Amoxicillin hydrolysate Derivatives against Resistant Bacteria". Pharmaceutics 12 3 (2020): 221-221. https://doi.org/10.3390/pharmaceutics12030221.
    Open access • Published • 10.3390/pharmaceutics12030221
  13. Sónia Teixeira; Miguel M. Santos; Ricardo Ferraz; Cristina Prudêncio; Maria H. Fernandes; João Costa-Rodrigues; Luís C. Branco. "A Novel Approach for Bisphosphonates: Ionic Liquids and Organic Salts from Zoledronic Acid". ChemMedChem (2019): https://doi.org/10.1002/cmdc.201900397.
    10.1002/cmdc.201900397
  14. Santos MM; Raposo LR; Costa A; Dionísio M; Baptista PV; Fernandes AR; Branco LC. "Ionic Liquids and salts from Ibuprofen as promising innovative formulations of an old drug.". ChemMedChem (2019): http://europepmc.org/abstract/med/30735308.
    10.1002/cmdc.201900040
  15. Ruivo, A.; Coutino-Gonzalez, E.; Santos, M. M.; Baekelant, W.; Fron, E.; Roeffaers, M.B.J.; Pina, F.; Hofkens, J.; Laia, C.A.T.. "Highly Photoluminescent Sulfide Clusters Confined in Zeolites". The Journal of Physical Chemistry C 122 26 (2018): 14761-14770. http://dx.doi.org/10.1021/acs.jpcc.8b01247.
    Published • 10.1021/acs.jpcc.8b01247
  16. Santos, Miguel M.; Bastos, Pedro; Catela, Isabelle; Zalewska, Karolina; Branco, Luis C.. "Recent Advances of Metallocenes for Medicinal Chemistry". Mini-Reviews in Medicinal Chemistry 17 9 (2017): 771-784. http://dx.doi.org/10.2174/1389557516666161031141620.
    Published • 10.2174/1389557516666161031141620
  17. Carrera, Gonçalo V. S. M.; Santos, Miguel M.; Costa, Alexandra; Rebelo, Luis Paulo N.; Marrucho, Isabel M.; Nunes da Ponte, M.; Branco, Luis C.; et al. "Highly water soluble room temperature superionic liquids of APIs". New Journal of Chemistry 41 15 (2017): 6986-6990. http://dx.doi.org/10.1039/c7nj01398a.
    Published • 10.1039/c7nj01398a
  18. Ferraz, Ricardo; Costa-Rodrigues, João; Fernandes, Maria H.; Santos, Miguel M.; Marrucho, Isabel M.; Rebelo, Luís Paulo N.; Prudêncio, Cristina; et al. "Antitumor Activity of Ionic Liquids Based on Ampicillin". ChemMedChem 10 9 (2015): 1480-1483. http://dx.doi.org/10.1002/cmdc.201500142.
    Published • 10.1002/cmdc.201500142
  19. Carrera, Gonçalo V. S. M.; Jordão, Noémi; Santos, Miguel M.; da Ponte, Manuel Nunes; Branco, Luís C.. "Reversible systems based on CO2, amino-acids and organic superbases". RSC Advances 5 45 (2015): 35564-35571. http://dx.doi.org/10.1039/c5ra03474d.
    Published • 10.1039/c5ra03474d
  20. Santos, Miguel M.; Marques, Igor; Carvalho, Sílvia; Moiteiro, Cristina; Félix, Vítor. "Recognition of bio-relevant dicarboxylate anions by an azacalix[2]arene[2]triazine derivative decorated with urea moieties". Organic & Biomolecular Chemistry 13 10 (2015): 3070-3085. http://dx.doi.org/10.1039/c4ob02283a.
    Published • 10.1039/c4ob02283a
  21. Areces, Pilar; Plumet, Joaquín; Carrasco, Esther; Light, Mark; Santos, Miguel. "Synthesis of Enantiopure 4-(Dihydroxyalkyl)-ß-lactams from d-Mannitol Using Ley’s BDA-Protected l-Glyceraldehyde". Synlett 2007 20 (2007): 3180-3182. http://dx.doi.org/10.1055/s-2007-992375.
    Published • 10.1055/s-2007-992375
Journal issue
  1. Miguel M. Santos; Petrovski, Zeljko. "Therapeutic Formulations of Repurposed Drugs against COVID-19". Pharmaceutics (2022): https://www.mdpi.com/journal/pharmaceutics/special_issues/drugs_COVID_19.
    Published • Invited editor
  2. Miguel M. Santos; Luis C. Branco. "Ionic Liquids and Deep Eutectic Solvents for Application in Pharmaceutics (Volume II)". Pharmaceutics (2020): https://www.mdpi.com/journal/pharmaceutics/special_issues/ILs_DES_II.
    Published • Invited editor
  3. Miguel M. Santos; Luis C. Branco. "Ionic Liquids and Deep Eutectic Solvents for Application in Pharmaceutics". Pharmaceutics (2020): https://www.mdpi.com/journal/pharmaceutics/special_issues/ILs_DES.
    Published • Invited editor
Thesis / Dissertation
  1. Miguel M. Santos. "Anion receptors based on azacalix[4]arenes and isoftalamides". PhD, Universidade de Aveiro, 2013. http://hdl.handle.net/10773/12376.
  2. Miguel M. Santos. "Glycosilation of phenolic compounds with heterogeneous catalysis promoted by acid zeolites". Master, Fundação da Faculdade de Ciências da Universidade de Lisboa, 2008. http://hdl.handle.net/10451/1279.
  3. Miguel M. Santos. "Synthesis of sulfenamides and carbamates and determination of protease inhibition activity". Degree, Fundação da Faculdade de Ciências da Universidade de Lisboa, 2006.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2021/05/27 Enhanced formulations of Hydroxychloroquine as Organic Salts and Ionic Liquids to fight COVID-19 European Chemical Biology Symposium
EuChemS, EUOpenscreen, Società Chimica Italiana (Germany)
2021/04/22 Ionic Liquids and Eutectic Systems as designer materials for Sustainable Goals IMIL Webinars
University of Santiago de Chile (Chile)
2020/11/01 Antitumor and osteogenic activity of bisphosphonate-based Organic Salts and Ionic Liquids 6th International Electronic Conference on Medicinal Chemistry
MDPI
2020/09 Task-Specific Ionic Liquids for Pharmaceutical Applications PATh/IonCytDevice Virtual Workshop
2020/01 Active Pharmaceutical Ionic Liquids as new platform for Tuberculosis 13th National Organic Chemistry Meeting - 6th National Medicinal Chemistry Meeting
(Aveiro, Portugal)
2019/12 Ionic Systems based on Pharmaceutical drugs 3rd International Christmas Caparica Congress in Translational Chemistry (IC3TC- 2019)
(Caparica, Portugal)
2018/11 Ionic Systems Approach for Pharmaceuticals XXIV Encontro Luso-Galego de Química
(Porto, Portugal)
2018/05/17 New perspective on osteosarcoma using bisphosphonate-based Ionic Liquids 6th PYChem
(Portugal)
2017/12 Innovative Salts for Materials Science and Pharmaceuticals 2nd International Christmas Caparica Congress in Translational Chemistry (IC3TC- 2017)
(Caparica, Portugal)
2016/11 Task-Specific Ionic Liquids for pharmaceutical applications XXII Encontro Luso-Galego Quimica
(Bragança, Portugal)
2015/12/02 Pharmaceutical Ionic Liquids and Salts as antitumor agents Congresso Química Orgânica e Química Terapêutica da Sociedade Portuguesa de Química
2015/12 Organic Superbases as useful tools for synthesis and applications 11º Encontro de Química Orgânica/ 4º Encontro de Química Terapêutica
(Porto, Portugal)
2015/06 Innovative Approaches for Drug Delivery and Antibiotic Resistance 6th EuChemS Life Sciences
(Lisboa, Portugal)
2008/06/16 Zeolites as Green and Efficient Catalysts for Key Transformations in Carbohydrate Chemistry Symposium in Honour of Eric Derouane

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2021/03 - Current Transdermal delivery of antibiotic drugs as Ionic Liquids and Organic Salts to tackle antimicrobial resistance
Supervisor of Francisco Luís de Aragão Faísca
 Química Sustentável (PhD)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Universidade do Porto Faculdade de Farmácia, Portugal
2020/09/10 - Current New fight against tuberculosis using pharmaceutical ionic liquids
Supervisor of Hugo Alexandre Almeida Quaresma de Albuquerque Araújo
 Química Bioorgânica (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2019/10/10 - 2021/02/17 Organic Salts and Ionic Liquids based on fluoroquinolone: synthesis, characterization and antimicrobial activity
Supervisor of Diogo Amaral Antunes Madeira
 Química Bioorgânica (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2019/10/11 - 2021/02/10 Development of bio-based binders for production of cork stoppers
Supervisor of Erikson Santos Leal Juvenal
 Química Bioorgânica (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2020/01/28 - 2020/10/04 Antibiotic-based nanoionic systems - synthesis, characterization and controlled release studies
Co-supervisor of Gonçalo Jasmins
 Química Aplicada (Degree)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2020/01/29 - 2020/07/09 Ionic Liquids and eutectic mixtures from drugs - synthesis, characterization and controlled release studies
Supervisor of Mariana Machado
 Química Aplicada (Degree)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2018/10/03 - 2019/10/30 Strategies for the stabilization and preservation of prosthetic heart valves
Supervisor of Daniel Mendes Leira Landum
 Química Bioorgânica (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2019/02/01 - 2019/10/15 Ionic Liquids from beta-lactam antibiotics - synthesis, characterization and antimicrobial activity
Supervisor of Núria Liandra de Oliveira Inácio
 Bioquímica (Degree)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2019/01/22 - 2019/03/15 Ionic Liquids from drugs as strategies for the modulation of bioavailability and toxicity
Supervisor of Tomás Soares
 Ciências de Engenharia Química e Bioquímica (Degree)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2019/01/22 - 2019/03/15 Preservation and fixation of bovine pericardium for assembly of prosthetic heart valves
Supervisor of Catarina Pinto
 Ciências de Engenharia Química e Bioquímica (Degree)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2018/01/19 - 2018/10/21 Novel Ionic Liquids with potential antiviral activity
Supervisor of Diogo Amaral Antunes Madeira
 Bioquímica (Degree)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2018/01/14 - 2018/10/02 Antimicrobial Ionic Liquids - synthesis, biological activity and mechanism of action
Supervisor of Bárbara Morna Padrão Soares
 Bioquímica (Degree)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2017/01/19 - 2017/10/05 Development and characterization of Ionic Liquids from beta-lactam antibiotics
Co-supervisor of Luís Pedro Serra Pinheiro
 Química Aplicada (Degree)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2017/01/26 - 2017/10/04 Novel organic salts and ionic liquids with potential antiviral and antituberculostatic activity
Co-supervisor of Daniel Leiria Mendes Landum
 Bioquímica (Degree)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2018/05/18 - Current Chairman of session in 6th Portuguese Young Chemists Meeting (2018/05/15 - 2018/05/18)
Meeting (Other)
2018/01/01 - 2018/05/18 Member of the organizing Comittee of the 6th Portuguese Young Chemistry Conference. (2018/05/15 - 2018/05/18)
Congress (Member of the Organising Committee)
2015/01/01 - 2015/07/16 Organizing committee of the 19th European Symposium on Organic Chemistry (2015/07/10 - 2015/07/16)
Symposium (Member of the Organising Committee)
 Universidade de Lisboa Faculdade de Ciências, Portugal

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2022/01/27 Enhaced water solubility of ibuprofen and ketoprofen using choline-based ionic liquids
(Thesis) Main arguer
 Cátia Alcobia (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Association member

Society Organization name Role
2018/09/01 - Current Portuguese Society of Chemistry Associate member
2017/07/21 - Current LAQV & UCIBIO Postdoctoral Association Events group member

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2021/10/01 - 2022/02/28 General and Inorganic Chemistry Farmácia (Licenciatura) Instituto Politécnico de Lisboa Escola Superior de Tecnologia da Saúde de Lisboa, Portugal
2021/10/01 - 2022/02/28 Applied Chemistry Saúde Ambiental (Licenciatura) Instituto Politécnico de Lisboa Escola Superior de Tecnologia da Saúde de Lisboa, Portugal
2020/10/15 - 2021/02/14 General and inorganic chemistry Farmácia (Licenciatura) Instituto Politécnico de Lisboa Escola Superior de Tecnologia da Saúde de Lisboa, Portugal
2020/09/15 - 2021/02/14 Applied Chemistry Saúde Ambiental (Licenciatura) Instituto Politécnico de Lisboa Escola Superior de Tecnologia da Saúde de Lisboa, Portugal
2019/09/15 - 2020/02/14 Applied Chemistry Saúde Ambiental (Licenciatura) Instituto Politécnico de Lisboa Escola Superior de Tecnologia da Saúde de Lisboa, Portugal

Interview (newspaper / magazine)

Activity description Newspaper / Forum
2020/07/12 Interview about the research project "Repurposed antimalaria and anti-ebola drugs as Organic Salts and Ionic Liquids to prevent and fight COVID-19" - RESEARCH 4 COVID-19 2nd ed n.582. Diário de Notícias

Interview (tv / radio show)

Program Topic
2020/07/23 - Current Antena 1 (radio) news on project "Repurposed antimalarial and anti-ebola drugs as organic salts and ionic liquids to prevent and fight covid-19" Portuguese researchers study new drug to prevent and treat COVID-19

Journal scientific committee

Journal title (ISSN) Publisher
2022/01/01 - Current Molecules (1420-3049) MDPI
2021/10/01 - Current International Journal of Molecular Sciences (1422-0067) MDPI
2021/05/01 - Current Biomaterials (0142-9612) Elsevier
2021/03/02 - Current PLOS ONE (1932-6203) Public Library of Science
2021/02/23 - Current ACS Infectious Diseases (2373-8227) American Chemical Society
2020/11/10 - Current Thermo (2673-7264) MDPI
2020/10/01 - Current Metals (2075-4701) MDPI
2020/09/10 - Current International Journal of Pharmacy and Chemistry (2575-5749) Science Publishing Group
2020/05/18 - Current Sustainable Chemistry (2673-4079) MDPI
2020/04/07 - Current Pharmaceutics (1999-4923) MDPI AG
2020/02/20 - Current Nanomaterials (2079-4991) MDPI AG
Distinctions

Other distinction

2020 ChemMedChem Hot Topic 2020 - A special collection featuring Cancer Research
John Wiley & Sons Inc, United States