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Sílvia Soares, Licenciada em Radioterapia pela Escola Superior de Saúde do Porto e Mestrado em Oncologia obtido pelo ICBAS. Doutorada em Ciência biomédicas no Instituto de Ciências Biomédicas Abel Salazar da Universidade do Porto (ICBAS) e em Nanomedicina pela Universidade de Vigo. O seu foco de investigação centra-se no desenvolvimento de um naonosistema à base de nanopartículas de ouro para melhorar a eficácia da radioterapia.
Identification

Personal identification

Full name
Sílvia Carneiro Soares

Citation names

  • Soares, Sílvia

Author identifiers

Ciência ID
4E15-0271-07C6
ORCID iD
0000-0002-4344-7860

Knowledge fields

  • Medical and Health Sciences - Clinical Medicine - Oncology

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Intermediate (B1) Upper intermediate (B2) Intermediate (B1) Intermediate (B1) Intermediate (B1)
Education
Degree Classification
2018/09/01 - 2023/07/20
Concluded
Ciências Biomédicas (Doutoramento)
Instituto de Ciências Biomédicas Abel Salazar da Universidade do Porto, Portugal
"Nanotheranostics with microRNA: applications in radiotherapy" (THESIS/DISSERTATION)
Aprovado por unanimidade
2018/02/01 - 2023/07/20
Concluded
Nanomedicine (Doktor (PhD))
Universidade de Vigo, Spain
"Nanotheranostics with microRNA: applications in radiotherapy" (THESIS/DISSERTATION)
Aprovado com Sobresaliente
2014/09/23 - 2016/11/22
Concluded
Oncologia (Mestrado)
Instituto de Ciências Biomédicas Abel Salazar da Universidade do Porto, Portugal
"Análise de polimorfismos genéticos nos genes ERCCI e XRCC3 e a sua influência na resposta ao tratamento de doentes com cancro do colo do útero" (THESIS/DISSERTATION)
18
2010/09/29 - 2014/07/12
Concluded
Radioterapia (Licenciatura)
Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
"PLESIOTHERAPY IN THE TREATMENT OF PRIMARY CUTANEOUS LESIONS OR HAVE IRRADIATED" (THESIS/DISSERTATION)
17
Affiliation

Science

Category
Host institution
Employer
2023/02/01 - 2023/12/31 Researcher (Research) Liga Portuguesa Contra o Cancro Núcleo Regional do Norte, Portugal
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2018/09/01 - 2023/01/31 Researcher (Research) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
(...)
2015/09/01 - 2016/11/22 Research Trainee (Research) Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal

Other Careers

Category
Host institution
Employer
2024/01/16 - Current Técnico de 2ª Classe (Técnico de Diagnóstico e Terapêutica - Técnico de Radioterapia) Centro Hospitalar Universitário de São João, Portugal
Centro Hospitalar Universitário de São João, Portugal

Others

Category
Host institution
Employer
2013/12/10 - 2014/04/30 Estagiária Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
2013/09/17 - 2013/12/06 Estagiária Centro Hospitalar Universitário de São João, Portugal
Centro Hospitalar Universitário de São João, Portugal
Projects

Grant

Designation Funders
2023/02/01 - 2023/12/31 MiRNA conjugated with gold nanoparticles as anti-angiogenic and radiosensitizing therapy for prostate cancer cells
Research Fellow
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Liga Portuguesa Contra o Cancro Núcleo Regional do Norte
Ongoing
2018/09/01 - 2023/01/31 NANOTHERANOSTICS WITH MIRNA: APPLICATION IN RADIOTHERAPY
SFRH/BD/138271/2018
PhD Student Fellow
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Instituto Politécnico do Porto Instituto Superior de Engenharia do Porto, Portugal

Universidade de Vigo, Spain
Fundação para a Ciência e a Tecnologia
Ongoing

Contract

Designation Funders
2023/01/01 - 2024/01/31 APTAMER - Application of Prostate Theranostic Aptamers for Macrophage Enhanced Response
FCT: 2022.09032.PTDC
Researcher
Hospital Fernando Pessoa, Portugal
Associação para a Inovação e Desenvolvimento da FCT
Ongoing

Other

Designation Funders
2014/09/01 - 2016/07/31 Análise de polimorfismos genéticos nos genes ERCCI e XRCC3 e a sua influência na resposta ao tratamento de doentes com cancro do colo do útero
Master Student Fellow
Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
Concluded
2013/09/01 - 2014/07/31 DOSIMETRIAS COMPLEXAS DE BRAQUITERAPIA: PLESIOTERAPIA NO TRATAMENTO DE LESÕES CUTÂNEAS PRIMÁRIAS OU JÁ IRRADIADAS
sem referencia
Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
Concluded
Outputs

Publications

Journal article
  1. Sílvia Soares; Fátima Aires; Armanda Monteiro; Gabriela Pinto; Isabel Faria; Goreti Sales; Miguel A. Correa-Duarte; Susana Guerreiro; Rúben Fernandes. "Radiotherapy Metastatic Prostate Cancer Cell Lines Treated with Gold Nanorods Modulate miRNA Signatures". International Journal of Molecular Sciences (2024): https://doi.org/10.3390/ijms25052754.
    10.3390/ijms25052754
  2. Marco Oliveira; André Sousa; Sara Sá; Sílvia Soares; Ana Cláudia Pereira; Ana Catarina Rocha; Patrick Pais; et al. "Harvesting the Power of Green Synthesis: Gold Nanoparticles Tailored for Prostate Cancer Therapy". International Journal of Molecular Sciences (2024): https://doi.org/10.3390/ijms25042277.
    10.3390/ijms25042277
Newspaper article
  1. Marco Oliveira; Silvia Soares; Sara Sá; Álvaro Gestoso; Miguel Correa-Duarte; Pilar Baylina; Rúben Fernandes; Carla F. Pereira. "The Magic Cocktail: Ampicillin and Biosynthesized Gold Nanoparticles Synergism against Staphylococcus aureus", Applied Sciences, 2023, https://doi.org/10.3390/app131910934.
    10.3390/app131910934
  2. Sílvia Soares; Cláudia Pereira; André Sousa; Ana Catarina Oliveira; Goreti Sales; Miguel A. Correa-Duarte; Guerreiro, Susana Gomes; Rúben Fernandes. "Metabolic Disruption of Gold Nanospheres, Nanostars and Nanorods in Human Metastatic Prostate Cancer Cells", Cells, 2023, https://www.mdpi.com/2073-4409/12/5/787.
    10.3390/cells12050787
  3. Sílvia Soares; Isabel Faria; Fátima Aires; Armanda Monteiro; Gabriela Pinto; Goreti Sales; Miguel A. Correa-Duarte; Guerreiro, Susana Gomes; Rúben Fernandes. "Application of Gold Nanoparticles as Radiosensitizer for Metastatic Prostate Cancer Cell Lines", International Journal of Molecular Sciences, 2023, https://www.mdpi.com/1422-0067/24/4/4122.
    10.3390/ijms24044122
  4. Susana G. Guerreiro; Natália Cruz-Martins; Isabel Faria; Pilar Baylina; Maria Goreti Sales; Miguel A. Correa-Duarte; Rúben Fernandes. "The Influence of miRNAs on Radiotherapy Treatment in Prostate Cancer – A Systematic Review", Frontiers in Oncology, 2021, http://dx.doi.org/10.3389/fonc.2021.704664.
    10.3389/fonc.2021.704664
  5. Augusto Nogueira ; Sílvia Soares; Joana Assis; Deolinda Pereira; Isabel Bravo ; Raquel Catarino ; Rui Medeiros. "TP53 Arg72Pro polymorphism is associated with increased overall survival but not response to therapy in Portuguese/Caucasian patients with advanced cervical cancer", Oncology Letters, 2018, http://dx.doi.org/10.3892/ol.2018.8354.
    10.3892/ol.2018.8354
  6. Augusto Nogueira ; Ana Coelho; Joana Assis; Deolinda Pereira; Isabel Bravo; Rui Medeiros. "Relationship between clinical toxicities and ERCC1 rs3212986 and XRCC3 rs861539 polymorphisms in cervical cancer patients", Int J Biol Markers, 2017, https://www.ncbi.nlm.nih.gov/pubmed/?term=ercc1+xrcc3+soares.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2022/04/25 "Gold nanoparticles as therapeutic agent for radiotherapy of PC3 prostate cancer cell line" 3rd International online conference on Nanomaterials
MDPI
2021/10/16 Nanoteranóstico com microRNA: Aplicação em Radioterapia Congresso Nacional da Associação Portuguesa de Radioterapeutas (CNART2021)
Associação Portuguesa de Radioterapeutas (Coimbra)
2021/10/15 Nanotheranostic with microRNA: Application in Radiotherapy National Congress of the Portuguese Association of Radiotherapists (CNART2021)
Portuguese Association of Radiotherapists (Coimbra, Portugal)
2021/09/06 Gold nanorods as radiosensitizer agents on PC3 cells NANOPORTUGAL (NPTO2021)
Phantoms foundation (Online)
2021/02/19 The effect of shape of gold nanoparticles in cytotoxicity of prostate cancer cell lines Congresso Nacional de Biomecânica
Sociedade Portuguesa de Biomecânica (Porto, Portugal)
2019/12/20 Surface functionalization of gold nanoparticles to delivery miRNA to prostate cancer cells 2ºEncontro Doutoramento de Ciências Biomédicas do ICBAS
Instituto de Ciências Biomédicas Abel Salazar (Porto, Portugal)
2019/07/17 Nanotheranostics with miRNA: Application in Radiotherapy Congresso "8th Iberian Meeting on Colloids and Interfaces" - RICI8
Grupo Especializado de Coloides e Interfases (GECI) of the Real Sociedad Española de Química (RSEQ) and the Real Sociedad Española de Física (RSEF), and the Grupo de Colóides, Polímeros e Interfaces of the Sociedade Portuguesa de Química (SPQ) (Aveiro)
2018/06/26 Nanotechnology - Oncology applications Medical Biotechnology course
School of Health and Technology of Porto (Vila Nova de Gaia, Portugal)
2015/03/16 Radiosurgery in the treatment of kidney carcinoma metastasis Methods and techniques in Nuclear Medicine VI
School of Health and Technology of Porto ( Vila Nova de Gaia, Portugal)
2015/03/16 Dosimetry in the central nervous system treatment planning Curricular unit of Methods and techniques in Nuclear Medicine VI
School of Health and Technology of Porto (Vila Nova de Gaia, Portugal)
2015/03/11 Radiosurgery vs. Gamma Knife Curricular unit of Methods and Techniques in Nuclear Medicine VI
School of Health and Technology of Porto (Vila Nova de Gaia, Portugal)
2015/03/11 Total Body Irradiation - a case Curricular unit of Methods and Techniques in Nuclear Medicine VI
School of Health and Technology of Porto (Vila Nova de Gaia, Portugal)

Event organisation

Event name
Type of event (Role)
Institution / Organization
2022/03/14 - Current Member of the organizing committee - Cell Fluorescence applications (2022/03/14)
Conference (Member of the Organising Committee)
Hospital-Escola da Universidade Fernando Pessoa, Portugal
2014/05/30 - Current Member of the scientific and organizing committee 2013-2014 of the V "Jornadas de Radioterapia" (2014/05/30)
Conference (Member of the Organising Committee)
Instituto Politécnico do Porto Escola Superior de Saúde, Portugal

Event participation

Activity description
Type of event
Event name
Institution / Organization
2022/09/24 - Current Apresentação de poster - " Radiosensitization of prostate cancer cells with gold nanoparticles"
Meeting
4th National Meeting of Young Researchers in Oncology
Liga Portuguesa Contra o Cancro Núcleo Regional do Norte, Portugal
2015/05/15 - Current Apresentação de poster - "Complicated dosimetry in Brachytherapy - Plesiotherapy in the treatment of primary cutaneous lesions or have irradiated"
Congress
2nd Luso-Brazilian Congress of Oncology
Sociedade Portuguesa de Oncologia, Portugal
2024/05/09 - 2024/05/11 Poster apresentação - Expressão Diferencial dos Genes de Enzimas do Metabolismo em Células PC3 (Carcinoma de Próstata) Expostas a Nanopartículas de Ouro
Conference
IPO Porto Summit
Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
2023/03/16 - 2023/03/18 Apresentação de poster - Modelo 3D co-cultura de pele: o papel da fosfatase alcalina e colagénio na vascularização. Uma estratégia na cicatrização da úlcer diabética
Congress
19.º Congresso Português de Diabetes
Sociedade Portuguesa de Diabetologia, Portugal
2022/05/12 - 2022/05/13 Apresentação de poster - "Uptake of AuNPstar by PC3 prostate cancer cell line submitted to a radiotherapy"
Meeting
28th Porto Cancer MEETING
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2021/06/30 - 2021/07/01 Apresentação de poster - "Gold nanoparticles as suppress migration and proliferation agent on radiotherapy treatments applied to PC3 cells"
Meeting
4th annual meeting CINBIO
Universidade de Vigo, Spain
2021/06/30 - 2021/07/01 Apresentação de poster - "Biosynthesis of gold nanoparticles by Pseudomonas aeruginosa with therapeutical potential in prostate carcinoma"
Meeting
4th annual meeting CINBIO
Universidade de Vigo, Spain
2021/06/27 - 2021/06/29 Apresentação de poster - "Nanotheranostics with gold nanoparticles applyed to Radiotherapy"
Meeting
Meeting with Science and Technology in Portugal
Fundação para a Ciência e a Tecnologia, Portugal
2021/05/05 - 2021/05/06 Apresentação de poster - "Effect of different shapes of pegylated gold nanoparticles on prostate cancer cells proliferation: in vitro assays Nanotheranostics with gold nanoparticles applied to Radiotherapy" in , (INL), 5-6 May 2021, Braga, Portugal
Conference
EuroNanoForum
International Iberian Nanotechnology Laboratory, Portugal
2021/03/18 - 2021/03/21 Apresentação de poster - "Does diabetic secretome encloses the key to fight prostate cancer?"
Meeting
AIMS meeting
Universidade de Lisboa Faculdade de Medicina, Portugal
2016/04/27 - 2016/04/28 Apresentação de poster - "ERCC1 C8092A (rS3212986) polymorphism: a prognostic value in cervical cancer"
Congress
2nd ASPIC International Congress
Associação Portuguesa de Investigação em Cancro, Portugal
2015/04/23 - 2015/04/27 Apresentação de poster - " Primary facial skin cancer and skin metastatic breast cancer successfully treated with HDR Plesiotherapy" 3rd ESTRO forum
European Society Radiation Oncology, Belgium

Interview (tv / radio show)

Program Topic
2023/03/18 - 2023/03/18 Entevista televisão - "Bom dia Portugal Fim de Semana" Tratamento inovador no cancro da próstata com nanoparticulas de ouro
2023/02/03 - 2023/02/03 Entevista televisão - "Portugal em direto" Vencedora de bolsa da Liga Portuguesa Contra o Cancro, Núcleo Regional do Norte
Distinctions

Award

2024 Award for best poster "Expressão Diferencial dos Genes de Enzimas do Metabolismo em Células PC3 (Carcinoma de Próstata) Expostas a Nanopartículas de Ouro"
Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
2024 Award for best poster with the theme "Citossensor eletroquímico para deteção de Células Tumorais Circulantes"
Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
2023 Award for best poster with the theme "Radiotherapy and gold nanorods modulate miRNA expression in metastatic prostate cancer cell lines
ATARP – Portuguese Association of Radiology, Radiotherapy and Nuclear Medicine Technicians , Portugal
2015 Best Student award 2014 Certificate of best finalist student, in recognition of his performance as a graduate student in Radiotherapy in the academic year 2013/2014
Instituto Politécnico do Porto Escola Superior de Saúde, Portugal

Other distinction

2022 Research Grant
Liga Portuguesa Contra o Cancro Núcleo Regional do Norte, Portugal
2018 PhD research grant (SFRH/BD/138271/2018)
Associação para a Inovação e Desenvolvimento da FCT, Portugal
2015 Merit certificate from the Polytechnic of Porto Diploma of exceptional academic performance in the academic year 2011/2012 in the Radiotherapy course
Instituto Politécnico do Porto, Portugal
2014 Award for best poster at the 5th Radiotherapy Days organized by School of Health and Technology of Porto
Instituto Politécnico do Porto Escola Superior de Saúde, Portugal