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Henrique Faneca completed the PhD in Biochemistry in 2005 by University of Coimbra. He is Principal Investigator at Centre for Neuroscience and Cell Biology, University of Coimbra, leading the group of Nanosystems and Targeted Antitumor Strategies. His research activity has been mainly focused on the development and characterization of novel gene and drug delivery nanosystems, and on the generation of antitumor strategies involving, among others, the combination of gene therapy and chemotherapy. He is author/coauthor of 51 papers in international peer-reviewed journals (with a cumulative impact factor of 326), 6 book chapters and more than 100 scientific communications, 23 of them as invited speaker, corresponding to over 2100 citations and to an h-index of 26 (Scopus). He has been involved in 52 supervisions (4 Postdoc projects, 9 PhD students, 27 Master students, and 12 Degree students), 41 as supervisor and 11 as co-supervisor. He is principal investigator of 5 financed project(s), and has been participating as team member in 12 national or international projects approved in competitive funding processes. He has been involved in different scientific evaluation committees, such as: remote referee in ERC call; reviewer of several peer-reviewed journals; member of the evaluation panel of funding calls; member of the evaluation panel of hired researchers; and as jury of PhD and Master exams. Moreover, he has been participating in several organizing and scientific committees of national and international congresses. He has been Guest Editor of Pharmaceutics (Q1) for the Special Issues Non-viral gene delivery systems and Non-viral gene delivery systems (volume II) and Associate Editor for Medicinal and Pharmaceutical Chemistry (specialty section Frontiers in Chemistry (Q1)). Additionally, he has been involved in teaching activities, at undergraduate and graduate levels, in several courses of the Faculty of Science and Technology of the University of Coimbra.
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Identification

Personal identification

Full name
Henrique Manuel Santos Faneca

Citation names

  • Faneca, Henrique

Author identifiers

Ciência ID
4E1F-D234-7CD6
ORCID iD
0000-0001-5554-7829

Email addresses

  • henrique@cnc.uc.pt (Professional)

Telephones

Fax
  • 239822776 (Professional)
Telephone
  • 239820190 (Professional)

Addresses

  • Centro de Neurociências e Biologia Celular de Coimbra. Faculdade de Medicina da Universidade de Coimbra, Polo I, 2º andar, 3004-517, Coimbra, Coimbra, Portugal (Professional)

Websites

Knowledge fields

  • Engineering and Technology - Nano-technology
  • Medical and Health Sciences - Medical Biotechnology
Outputs

Publications

Book chapter
  1. Faneca, H.; Düzgünes, N.; Pedroso de Lima, M.C.. "Suicide gene therapy for oral squamous cell carcinoma". 2019.
    Published • 10.1007/978-1-4939-8922-5_4
  2. Passadouro, M.; Faneca, Henrique (4E1F-D234-7CD6). Corresponding author: Faneca, Henrique (4E1F-D234-7CD6). "Combination of anti-miRNAs oligonucleotides with low amounts of chemotherapeutic agents for pancreatic cancer therapy". 2018.
    Published • 10.1007/978-1-4939-7435-1_11
  3. Faneca, Henrique; Cardoso, Ana Luísa; Trabulo, Sara; Duarte, Sónia; Pedroso de Lima MC. "Cationic liposome-based systems for nucleic acid delivery: from the formulation development to therapeutic applications.". 2013.
    Published • 10.1007/978-94-007-6010-3
  4. Düzgünes, N.; Faneca, H.; Lima, M.C.. "Methods to monitor liposome fusion, permeability, and interaction with cells.". In Methods in molecular biology (Clifton, N.J.), 209-232. 2010.
    Published • 10.1007/978-1-60761-447-0_16
  5. Faneca, H.; Düzgünes, N.; Lima, M.C.. "Fluorescence methods for evaluating lipoplex-mediated gene delivery.". In Methods in molecular biology (Clifton, N.J.), 425-437. 2010.
    Published • 10.1007/978-1-60761-447-0_29
  6. Pedroso De Lima, M.C.; Faneca, H.; Mano, M.; Penacho, N.; Düzgünes, N.; Simões, S.. "Biophysical characterization of cationic liposome-DNA complexes and their interaction with cells". 2003.
    Published • 10.1016/S0076-6879(03)73019-5
Conference abstract
  1. Pinto, Inês S.; Cordeiro, Rosemeyre A.; Faneca, Henrique. "Nanoparticle-enabled CAR T cell therapy: Unlocking new frontiers in cancer immunotherapy". Paper presented in EACR Congress, 2023.
    Published
  2. Pinto, Inês S.; Cordeiro, Rosemeyre A; Faneca, Henrique. "Nanoparticle-mediated T Cell Engineering for Improved Cancer Immunotherapy". Paper presented in VI iBiMED Symposium: From Fundamental Research to Clinical Practice, 2023.
    Published
  3. Cordeiro, Rosemeyre; Santo, Daniela; Farinha, Dina; Serra, Arménio; Coelho, Jorge; Faneca, Henrique. "High biological activity mediated by a tailor-made tri-block copolymer-based-nanovector". Paper presented in 5th Portuguese Meeting on Bioengineering, Coimbra, 2017.
    Published
  4. Santo, Daniela; Cordeiro, Rosemeyre A; Sousa, Ana; Serra, Arménio; Coelho, Jorge; Faneca, Henrique. "High gene delivery efficiency promoted by a combined polymeric-based nanosystem". Paper presented in 5th Portuguese Meeting on Bioengineering, Coimbra, 2017.
    Published
  5. Caetano, Marta Daniela Passadouro; Nobrega, Clévio; Pereira de Almeida, Luís; Pedroso de Lima, M.C.; Faneca, Henrique. "MicroRNA-139-5p: a tool for metastasis and chemotherapeutic resistance control in Pancreatic Adenocarcinoma". Paper presented in 23rd Biennial Congress of the European Association for Cancer Research, Munique, 2014.
    Published
  6. Cordeiro, R.; Santos, G.L.; Faneca, H.; Serra, A.C.; Coelho, J.F.J.. "Comparative biocompatibility evaluation of poly(ß-amino ester) and poly[2-(dimethylamino)ethyl methacrylate]". 2013.
    Published
  7. Cordeiro, R.; Santos, G.L.; Faneca, H.; Mendes, J.P.; Serra, A.C.; Coelho, J.F.J.. "Evaluation of the biocompatibility of cholesterol-poly[2-(dimethylamino)ethyl methacrylate] synthesized by atom transfer radical polymerization". 2013.
    Published
  8. Farinha, Dina Pereira Alves; Pedroso de Lima, M.C.; Faneca, Henrique. "A Novel Lipoplex Formulation for Targeted Cancer Gene Therapy". Paper presented in 22nd Biennial European Association of Cancer Research Congress, Barcelonna, 2012.
    Published
  9. Lebre, Filipa; G Borchard; Faneca, Henrique; Prof. Maria da Conceição Pedroso de Lima; Borges, Olga. "Development of chitosan nanoparticle-DNA complexes for nasal immunization against Hepatitis B". 2011.
    Published
  10. Moura MJ; Faneca, Henrique; Pedroso de Lima MC; Gil MH; Figueiredo MM. "The potential of a thermosensitive chitosan hydrogel cross-linked in situ with different loads of genipin". 2011.
    Published
  11. Duarte, Sónia; Faneca, Henrique; Pedroso de Lima MC. "Development of folate-lipid-based systems for tumour-targeted gene delivery". Paper presented in 21st Meeting of the European Association for Cancer Research, 2010.
    Published
  12. Caetano, Marta Daniela Passadouro; Carvalho, Eugénia; Metelo, AM; Faneca, Henrique; Pedroso de Lima, M.C.; Castro, Margarida. "The VO(dmpp)(2), a promising insulin mimetic vanadium compound". Paper presented in 45th Annual Meeting of the European-Association- for-the-Study-of-Diabetes, Viena, 2009.
    Published
  13. Rosmaninho-Salgado, Joana; Magda M Santana; Faneca, Henrique; Grouzmann, E; Cavadas, Claudia. "The increase of preadipocyte proliferation induced by DPPIV is inhibited by vildagliptin, Revista Portuguesa de Endocrinologia, Diabetes e Metabolismo". 2009.
    Published
  14. Duarte, Sónia; Faneca, Henrique; Trabulo, Sara; Cardoso, Ana Luísa; Pedroso de Lima MC. "Folate-associated cationic liposomes as a promising system for tumor-targeted gene delivery". Paper presented in European Society of Gene and Cell Therapy Meeting, 2008.
    Published
  15. Trabulo, Sara; Mano, Miguel; Faneca, Henrique; Cardoso, Ana Luísa; Duarte, Sónia; Gomes, Paula; Simões, Sérgio; Pedroso de Lima MC. "Association of S4 (13)-PV cell penetrating peptide with cationic liposomes: A synergistic effect on the intracellular delivery of plasmid DNA". Paper presented in 30th European Peptide Symposium - Cell Penetrating Peptides, 2008.
    Published
  16. Faneca, Henrique; Avecilla, F.; Palacio L; Figueiredo, Andreia; Pessoa JC; Geraldes CFGC; Pedroso De Lima, M.C.; Castro MMCA. "Study of the interaction in aqueous solution of vanadate with MHCPE, a heterocyclic pyrimidinone derivative ligand, by 51V NMR spectroscopy". Paper presented in V Symposium of Vanadium, 2006.
    Published
  17. Figueiredo, Andreia; Faneca, Henrique; Brotas G; Tomaz, I.; Correia, I; Pessoa JC; Geraldes CFGC; Pedroso de Lima, M.C.; Castro MMCA. "Evaluation of toxicity and insulin mimetic properties of vanadium compounds". Paper presented in V Symposium of Vanadium, 2006.
    Published
  18. Faneca, Henrique; Cabrita, António; Simões, Sérgio; Pedroso de Lima MC. "Antitumoral activity mediated by a lipid-based gene delivery system containing therapeutic genes". Paper presented in American Society of Gene Therapy 2006 Annual Meeting, 2006.
    Published
Conference poster
  1. Pinto, Inês S.; Cordeiro, Rosemeyre A; Faneca, Henrique. "Nano-immunotherapy: Boosting the innovative battle against cancer". Paper presented in EACR-AACR Basic and Translational Research Conference, 2024.
  2. Pinto, Inês S.; Cordeiro, Rosemeyre A; Faneca, Henrique. "Chloroquine as an adjuvant to nanotechnology in the development of CAR T cells". Paper presented in 5° National Meeting of Young Researchers in Oncology, 2023.
  3. Pinto, Inês S.; Cordeiro, Rosemeyre A; Faneca, Henrique. "Nanoparticles for CAR T cell manufacturing: a potential gene delivery platform". Paper presented in Defence is the Best Attack: Immuno-Oncology Breakthroughs - EACR conference, 2023.
  4. Pinto, Inês S.; Cordeiro, Rosemeyre A.; Faneca, Henrique. "Nanoparticles for T cell engineering: a potential gene delivery platform". Paper presented in 4th SPLC-CRS Young Scientists Meeting | Delivering Science, Bridging Opportunities, 2023.
  5. Inês Pinto; Cordeiro, Rosemeyre A; Faneca, Henrique. "Synthesis and characterization of polymeric nanoparticles for T cell-based cancer immunotherapy". Paper presented in UT Austin Portugal Annual Conference 2022, 2022.
  6. Pinto, Inês; Cordeiro, Rosemeyre A; Faneca, Henrique. "Polymer-based nanosystems for gene delivery into T cell". Paper presented in 4° National Meeting of Young Researchers in Oncology, 2022.
  7. Pinto, Inês S.; Cordeiro, Rosemeyre A; Faneca, Henrique. "Polymer-based nanosystems for gene delivery to T lymphocytes". Paper presented in 4° National Meeting of Young Researchers in Oncology, 2022.
  8. Pinto, Inês; Cordeiro, Rosemeyre A; Faneca, Henrique. "Novel polymer-based nanosystems for T cell engineering". Paper presented in Master Day on Department of Medical Sciences at University of Aveiro, 2022.
  9. Dina Farinha; Michael Migawa; Ana Bela Sarmento-Ribeiro; Faneca, Henrique. "A specific delivery nanosystem to mediate a targeted antitumor strategy to HCC". Paper presented in BEB Day 2022 – The overview effect, 2022.
  10. Dina Farinha; Michael Migawa; Ana Bela Sarmento-Ribeiro; Faneca, Henrique. "A targeted and combined nanosystem-mediated antitumor strategy to HCC". Paper presented in Personalized and Precision Medicine International Conference 2021, 2021.
  11. Dina Farinha; Michael Migawa; Ana Bela Sarmento-Ribeiro; Faneca, Henrique. "A targeted delivery nanosystem to mediate a combined antitumor strategy to HCC". Paper presented in Applied Nanotechnology and Nanoscience International Conference 2021, 2021.
  12. Rosemeyre A. Cordeiro; Ana Maria Carvalho; Luísa Durães; Faneca, Henrique. "Redox-responsive mesoporous silica nanoparticles for cancer therapy". Paper presented in Applied Nanotechnology and Nanoscience International Conference 2021, 2021.
  13. Santo, Daniela; Mendonça, P; Lima, Mafalda; Cordeiro, Rosemeyre; Serra, A.; Coelho, J.F.; Faneca, Henrique. "Efficient gene delivery promoted by PEGylated poly(2-aminoethyl methacrylate hydrochloride)-based nanosystems.". Paper presented in 31st Nano Congress for Future Advancements, 2019.
  14. Farinha, Dina Pereira Alves; Faneca, Henrique. "A targeted drug delivery nanosystem to hepatocellular carcinoma". Paper presented in 31st Nano Congress for Future Advancements, 2019.
  15. Cordeiro, Rosemeyre; Carvalho, Ana Maria; Durães L; Faneca, Henrique. "Development of an efficient drug delivery nanosystem to tumor cells". Paper presented in 31st Nano Congress for Future Advancements, 2019.
  16. Farinha, Dina Pereira Alves; Faneca, Henrique. "Design of a new nanosystem for targeted drug delivery to hepatocellular carcinoma". Paper presented in 6th Nano Today Conference, 2019.
  17. Santo, Daniela; Cordeiro, Rosemeyre; Sousa, Ana; Serra, A.; Coelho, JF; Faneca, Henrique. "High gene delivery efficiency of a novel nanosystem based on a synergistic polymeric combination". Paper presented in XII Spanish-Portuguese Conference on Controlled Drug Delivery, 2018.
  18. Soares, Edna; Cordeiro, Rosemeyre; Borges, Olga; Faneca, Henrique. "Targeted polymeric nanoengineered HBsAg DNA vaccine". Paper presented in XII Spanish-Portuguese Conference on Controlled Drug Delivery, 2018.
  19. Cordeiro, Rosemeyre; Santo, Daniela; Farinha, Dina Pereira Alves; Serra, Arménio; Coelho, Jorge; Faneca, Henrique. "High biological activity mediated by a tailor-made tri-block copolymer-based on nanovector". Paper presented in 5th Portuguese Meeting on Bioengineering, 2017.
  20. Santo D,; Cordeiro, Rosemeyre; Sousa, Ana; Serra, Arménio; Coelho, J.F.; Faneca, Henrique. "High gene delivery efficiency promoted by a combined polymeric-based nanosystem". Paper presented in 5th Portuguese Meeting on Bioengineering, 2017.
  21. Passadouro, M.; Trabulo, Sara; Sainz B; Nobrega, Clévio; Almeida, Luís; Heesen C; Pedroso de Lima MC; Faneca, Henrique. "Pancreatic adenocarcinoma metastasis regulation and sensitization to chemotherapeutic drugs by mir-139-5p overexpression". Paper presented in XII Annual Meeting of CNC, 2014.
  22. Farinha, Dina Pereira Alves; Pedroso de Lima MC; Faneca, Henrique. "A Novel ASF-associated nanosystem for specific and efficient gene delivery". Paper presented in 5th International Congress Nanotechnology, Medicine & Biology, 2014.
  23. Passadouro, M.; Nobrega, Clévio; Almeida, Luís; Pedrosos de Lima, MC; Faneca, Henrique. "MicroRNA-139-5p: a tool for metastasis and chemotherapeutic resistance control in Pancreatic Adenocarcinoma". Paper presented in 23rd Biennial Congress of the European Association for Cancer Research, 2014.
  24. Magalhães, M.; Farinha, Dina Pereira Alves; Pedrosos de Lima, MC; Faneca, Henrique. "Development of a new lipid-based nanosystem for specific and efficient gene delivery into Hepatocellular Carcinoma". Paper presented in VII National Meeting of Biochemistry Students, 2014.
  25. Passadouro, M.; Nobrega, Clévio; Pereira de Almeida, Luís; Pedrosos de Lima, MC; Faneca, Henrique. "Mir-139-5p as a main regulator of the pro-metastatic chemokine receptor CXCR4 in pancreatic cancer and a cell sensitizer to chemotherapeutic agents". Paper presented in XI Annual Meeting of CNC, 2013.
  26. Passadouro, M.; Nobrega, Clévio; Pereira de Almeida, Luís; Pedrosos de Lima, MC; Faneca, Henrique. "Mir-139-5p: a metastasis inhibitor and a sensitizer to chemotherapeutic drugs in pancreatic cancer". Paper presented in 7th national meeting on cell signalling, 2013.
  27. Magalhães, M.; Farinha, D.; Pedrosos de Lima, MC; Faneca, Henrique. "Development of a new lipid-based nanosystem for specific and efficient gene delivery". Paper presented in Symposium "personalized medicine: myth or reality?", 2013.
  28. Cordeiro, Rosemeyre; Santos, Gabriela; Faneca, Henrique; Mendes JP; Serra AC; Coelho, JFJ. "Evaluation of the biocompatibility of cholesterol-poly[2-(dimethylamino)ethyl methacrylate] synthesized by atom transfer radical polymerization". Paper presented in IV International Symposium on Surface and Interface of Biomaterials, 2013.
  29. Cordeiro, Rosemeyre; Santos, Gabriela; Faneca, Henrique; Serra AC; Coelho, JFJ. "Comparative biocompatibility evaluation of poly(ß-amino ester) and poly[2-(dimethylamino)ethyl methacrylate]". Paper presented in IV International Symposium on Surface and Interface of Biomaterials, 2013.
  30. Passadouro, M.; Nobrega, Clévio; Pereira de Almeida, Luís; Pedrosos de Lima, MC; Faneca, Henrique. "Modulation of miR-139-5p expression as a therapeutic strategy for pancreatic cancer". Paper presented in EMBO Young Scientists's Forum, 2013.
  31. Santos, Gabriela; Pedrosos de Lima, MC; Faneca, Henrique. "Combining gene therapy and chemotherapy in a breast cancer therapeutic approach". Paper presented in 1st Research Coimbra in Health Sciences, 2013.
  32. Farinha, Dina Pereira Alves; Pedroso de Lima, M.C.; Faneca, Henrique. "A Novel lipoplex formulation for targeted cancer gene therapy". Paper presented in 22nd Biennial European Association of Cancer Research Congress, 2012.
  33. Lebre, Filipa; Borchard, G.; Faneca, Henrique; Pedroso de Lima, M.C.; Borges, Olga. "Albumin Loaded Chitosan Nanoparticles/DNA Complexes for Nasal Immunization". Paper presented in AAPS National Biotechnology Conference, 2012.
  34. Passadouro, M.; Pedroso de Lima, M.C.; Faneca, Henrique. "Development of a therapeutic strategy for pancreatic cancer involving the combination of anti-miRNA oligonucleotides with chemotherapeutic drugs". Paper presented in Portuguese RNA meeting 2012, 2012.
  35. Passadouro, M.; Pedroso de Lima, M.C.; Faneca, Henrique. "Antitumoral strategy for pancreatic cancer: microRNA’s silencing combined with chemotherapeutic drug". Paper presented in ncRNAs and Human Disease International Symposium, 2011.
  36. Moura MJ; Faneca, Henrique; Pedroso de Lima MC; Gil MH; Figueiredo MM. "The potential of a thermosensitive chitosan hydrogel cross-linked in situ with different loads of genipin". Paper presented in ICTE 2011 - II International Conference on Tissue Engineering, 2011.
  37. Ribas J; Faneca, Henrique; Pedroso de Lima MC; Ribeiro SM. "Ataxin-3 aggregation and its impact on membrane destabilization". Paper presented in 2nd I3S Scientific Retreat, 2011.
  38. Passadouro, M.; Pedroso de Lima, M.C.; Faneca, Henrique. "Antitumoral strategy involving combination of anti-miRNA oligonucleotides with chemotherapeutic drugs for pancreatic cancer". Paper presented in XX Porto Cancer Meeting, 2011.
  39. Duarte, Sónia; Faneca, Henrique; Pedroso de Lima MC. "A novel folate-associated lipoplex formulation for gene delivery: evaluation of the potential for HSV-tk/valganciclovir suicide gene therapy in vitro and in vivo". Paper presented in XX Porto Cancer Meeting, 2011.
  40. Faneca, Henrique; Amaral, Sara; Pedroso de Lima MC. "Synergistic Antitumoral Effect of Chemotherapeutic Agents and HSV-Tk/GCV Gene Therapy Mediated by Albumin-Associated Nanosystems". Paper presented in 7th International Conference on Nanosciences & Nanotechnologies, 2010.
  41. Duarte, Sónia; Faneca, Henrique; Pedroso de Lima MC. "Development of folate-lipid-based systems for tumor-targeted gene delivery". Paper presented in 21st Meeting of the European Association for Cancer Research, 2010.
  42. Almeida, João; Marques, Eduardo; Faneca, Henrique; Jurado, Amália; Pais, Alberto. "Cationic Gemini surfactants: Interaction with model lipid membranes". Paper presented in International Courses on Toxicology 2010 – Survival or Death as a Matter of Fat, 2010.
  43. Cardoso, A; Faneca, Henrique; Almeida, João; Pais, Alaberto; Marques, Eduardo; Pedrosos de Lima, MC; Jurado, Amália. "Biophysical properties and transfection ability of ethanediyl-alfa,omega-bis(-Ntetradecyl,N,N´,dimethylammonium bromide)-based vectors". Paper presented in International Courses on Toxicology 2010 – Survival or Death as a Matter of Fat, 2010.
  44. Rosmaninho-Salgado J; Faneca, Henrique; Grouzmann E; Cavadas, Claudia. "The increase of endogenous NPY Y2 agonist induced by dipeptidyl-peptidase IV (DPPIV) stimulates pre-adipocites proliferation". Paper presented in XXXIX Annual Meeting of the Portuguese Pharmacology Society, 2008.
  45. Trabulo, Sara; Costa Pedro; Resina, S; Mano, Miguel; Faneca, Henrique; Cardoso AL; Duarte, Sónia; et al. "S413-PV cell penetrating peptide associated with different cargos: assessment of delivery efficiency and internalization mechanisms". Paper presented in 30th European Peptide Symposium – Cell Penetrating Peptides Satellite Symposium, 2008.
  46. Neves, Sílvia; Faneca, Henrique; Bertin, S.; Konopka, K.; Düzgünes, N.; Pierrefite-Carle, V.; Simões, Sérgio; Pedrosos de Lima, MC. "Transferrin-lipoplex-mediated suicide gene therapy of oral squamous cell carcinoma in a murine model". Paper presented in Targeting Gene Therapy Symposium, Beyond Genome, 2008.
  47. Trabulo, Sara; Mano, Miguel; Faneca, Henrique; Cardoso AL; Simões, Sérgio; Pedroso de Lima MC. "A novel approach for the intracellular delivery of nucleic acids based on the S413-PV cell penetrating peptide". Paper presented in 2nd Workshop on Biophysics of Membrane-Active Peptides, 2007.
  48. Trabulo, Sara; Mano, Miguel; Faneca, Henrique; Cardoso AL; Simões, Sérgio; Pedroso de Lima MC. "S413-PV cell penetrating peptide-based strategies for the intracellular delivery of nucleic acids". Paper presented in Cell Penetrating Peptides Meeting, 2007.
  49. Trabulo, Sara; Mano, Miguel; Faneca, Henrique; Cardoso AL; Duarte, Sónia; Simões, Sérgio; Pedrosos de Lima, MC. "S413-PV cell penetrating peptide-based systems for the intracellular delivery of plasmid DNS and siRNA". Paper presented in V Annual Meeting of CNC, 2007.
  50. Castro MM; Avecilla, F.; Tomaz, I.; Gonçalves, G; Faneca, Henrique; Palacio L; Pedrosos de Lima, MC; Costa Pessoa J. "Vanadium compounds as insulin mimetic agents: chemical and biochemical studies of a pyrimidinone complex". Paper presented in Magnetic Resonance Conference "EUROMAR", 2007.
  51. Trabulo, Sara; Mano, Miguel; Faneca, Henrique; Cardoso AL; Duarte, Sónia; Simões, Sérgio; Pedroso de Lima MC. "Enhancement of the intracellular delivery of siRNA and plasmid DNA using S413-PV cell penetrating peptide-based systems". Paper presented in 2nd Intracellular delivery of therapeutic molecules – from concept to application, 2007.
  52. Castilho, A; Santos AE; Tomé RL; Faneca, Henrique; Pedrosos de Lima, MC; Carvalho, AL; Macedo-Ribeiro S. "Exploring the cytotoxicity of early ataxin-3 oligomers". Paper presented in XV National Congress of Biochemistry, 2006.
  53. Faneca, Henrique; Cabrita, A.S.; Simões, Sérgio; Pedrosos de Lima, MC. "Antitumoral activity mediated by a lipid-based gene delivery system containing therapeutic genes". Paper presented in American Society of Gene Therapy 2006 Annual Meeting, 2006.
  54. Figueiredo, A; Faneca, Henrique; Brotas G; Tomaz, I.; Correia, I.; Costa Pessoa J; Geraldes, C.F.G.C.; Pedrosos de Lima, MC; Castro MMCA. "Evaluation of toxicity and insulin mimetic properties of vanadium compound". Paper presented in V Symposium of Vanadium, 2006.
  55. Avecilla, F.; Palacio L; Figueiredo, A; Faneca, Henrique; Costa Pessoa J; Geraldes C; Pedroso de Lima MC; Castro MMCA. "Study of the interaction in aqueous solution of vanadate with MHCPE, a heterocyclic pyrimidinone derivative ligand, by 51V NMR spectroscopy". Paper presented in V Symposium of Vanadium, 2006.
  56. Silva-Lucca RA; Faneca, Henrique; Pedroso de Lima MC; Nakaie CR; Assis ML; Caroli FP; Sampaio MU. "Interaction of Bauhinia bauhinioides inhibitors and peptides derived from the reactive sites with phospholipid vesicles". Paper presented in Annual Congress of the Brazilian Society of Biochemistry and Molecular Biology, 2006.
  57. Figueiredo, A; Faneca, Henrique; Brotas G; Tomaz, I.; Correia, I; Costa Pessoa J; Geraldes C; Pedroso de Lima MC; Castro MMCA. "Vanadium Compounds as Therapeutic Agents: Some Biological Studies". Paper presented in 8th European Conference on Bioinorganic Chemistry, 2006.
  58. Avecilla, F.; Palacio L; Figueiredo, A; Faneca, Henrique; Costa Pessoa J; Geraldes C; Pedrosos de Lima, MC; Castro MMCA. "Interaction in aqueous solution of vanadate with MHCPE, a heterocyclic pyrimidinone derivative ligand: a 51V NMR study". Paper presented in 8th European Conference on Bioinorganic Chemistry, 2006.
  59. Faneca, Henrique; Simões, Sérgio; Colombo M; Pedroso de Lima MC. "Albumin-associated lipoplexes containing the IL-12 or the HSV-tk genes exhibit a significant antitumoral effect". Paper presented in 2nd Congress of the Portuguese Society of Pharmaceutical Sciences, 6th Spanish-Portuguese Chapter of the Controlled Release Society, 2005.
  60. Faneca, Henrique; Simões, Sérgio; Colombo M; Pedroso de Lima MC. "Intratumoral injection of albumin-associated lipoplexes containing the IL-12 or the HSV-tk genes aiming at anti-cancer therapy". Paper presented in 12th Annual Congress of the European Society of Gene Therapy, Tampere, Finland, 2004.
  61. Faneca, Henrique; Simões Sérgio; Pedrosos de Lima, MC. "Co-association of albumin and protamine to lipoplexes ensures a high degree of DNA protection and serum resistance". Paper presented in 11th Annual Congress of the European Society of Gene Therapy, 2003.
  62. Faneca, Henrique; Simões, Sérgio; Pedrosos de Lima, MC. "Association of albumin or protamine to lipoplexes: Enhancement of transfection and resistance to serum". Paper presented in V Spanish-Portuguese Conference on Controlled Drug Delivery, 2002.
  63. Penacho, N.; Faneca, Henrique; Simões, Sérgio; Pedrosos de Lima, MC. "Exploring protein internalization by receptor-mediated endocytosis to enhance intracellular gene delivery". Paper presented in 27th Meeting of the Federation of European Biochemical Societies, 2001.
  64. Pedrosos de Lima, MC; Simões, Sérgio; Pires, Pedro; Faneca, Henrique; Girão Teresa; Mano, Miguel; Penacho, N.. "Development of liposomes as gene delivery systems for application in gene therapy". Paper presented in II Congress of Research in Medicine, 2000.
  65. Penacho, N.; Faneca, Henrique; Simões, Sérgio; Pedrosos de Lima, MC. "Relationship between the biophysical properties and biological activity of lipoplexes". Paper presented in IV Spanish-Portuguese Conference on Controlled Drug Delivery, 2000.
  66. Penacho, N.; Faneca, Henrique; Simões, Sérgio; Pedrosos de Lima, MC. "Biophysical properties and biological activity of cationic liposome/DNA complexes". Paper presented in XII National Congress of Biochemistry, 2000.
  67. Faneca, Henrique; Simões, Sérgio; Pedrosos de Lima, MC. "Characterization of different lipid-based formulations for gene delivery". Paper presented in Targeting of Drugs: Stategies For Gene Constructs and Delivery, 1999.
Journal article
  1. Santo, Daniela; Mendonça, Patrícia V.; Serra, Arménio C.; Coelho, Jorge F.J.; Faneca, Henrique. Corresponding author: Faneca, Henrique. "Targeted downregulation of MYC mediated by a highly efficient lactobionic acid-based glycoplex to enhance chemosensitivity in human hepatocellular carcinoma cells". International Journal of Pharmaceutics 637 (2023): 122865-122882. http://dx.doi.org/10.1016/j.ijpharm.2023.122865.
    Open access • 10.1016/j.ijpharm.2023.122865
  2. Santo, Daniela; Cordeiro, Rosemeyre A.; Mendonça, Patrícia V.; Serra, Arménio C.; Coelho, Jorge F. J.; Faneca, Henrique. Corresponding author: Faneca, Henrique. "Glycopolymers Mediate Suicide Gene Therapy in ASGPR-Expressing Hepatocellular Carcinoma Cells in Tandem with Docetaxel". Biomacromolecules 24 3 (2023): 1274-1286. http://dx.doi.org/10.1021/acs.biomac.2c01329.
    10.1021/acs.biomac.2c01329
  3. Pinto, Inês S.; Cordeiro, Rosemeyre A.; Faneca, Henrique. Corresponding author: Faneca, Henrique. "Polymer- and lipid-based gene delivery technology for CAR T cell therapy". Journal of Controlled Release 353 (2023): 196-215. http://dx.doi.org/10.1016/j.jconrel.2022.11.038.
    Open access • Published • 10.1016/j.jconrel.2022.11.038
  4. Silva, Inês; Domingues, Cátia; Jarak, Ivana; Carvalho, Rui A.; Cordeiro, Rosemeyre A.; Dourado, Marília; Veiga, Francisco; Faneca, Henrique; Figueiras, Ana. "Novel Non-Viral Vectors Based on Pluronic® F68PEI with Application in Oncology Field". Polymers 14 23 (2022): 5315-5329. http://dx.doi.org/10.3390/polym14235315.
    Open access • Published • 10.3390/polym14235315
  5. Ferreira-Faria, Inês; Yousefiasl, Satar; Macário-Soares, Ana; Pereira-Silva, Miguel; Peixoto, Diana; Zafar, Hajra; Raza, Faisal; et al. "Stem cell membrane-coated abiotic nanomaterials for biomedical applications". Journal of Controlled Release 351 (2022): 174-197. http://dx.doi.org/10.1016/j.jconrel.2022.09.012.
    Published • 10.1016/j.jconrel.2022.09.012
  6. Cordeiro, Rosemeyre; Carvalho, Ana; Durães, Luísa; Faneca, Henrique. Corresponding author: Faneca, Henrique. "Triantennary GalNAc-Functionalized Multi-Responsive Mesoporous Silica Nanoparticles for Drug Delivery Targeted at Asialoglycoprotein Receptor". International Journal of Molecular Sciences 23 11 (2022): 6243-6260. http://dx.doi.org/10.3390/ijms23116243.
    Open access • 10.3390/ijms23116243
  7. Cordeiro, Rosemeyre A.; Mendonça, Patrícia V.; Coelho, Jorge; Faneca, Henrique. Corresponding author: Faneca, Henrique. "Engineering silica-polymer hybrid nanosystems for dual drug and gene delivery". Biomaterials Advances 135 (2022): 212742-212754. http://dx.doi.org/10.1016/j.bioadv.2022.212742.
    10.1016/j.bioadv.2022.212742
  8. Gonçalves, Filipa A M M; Fonseca, Ana C; Cordeiro, Rosemeyre; Piedade, Ana P; Faneca, Henrique; Serra, Arménio; Coelho, Jorge F J. "Fabrication of 3D scaffolds based on fully biobased unsaturated polyester resins by microstereo-lithography". Biomedical Materials 17 2 (2022): 025010-025021. http://dx.doi.org/10.1088/1748-605x/ac4b46.
    Published • 10.1088/1748-605x/ac4b46
  9. Ribeiro, Jessica P.M.; Mendonça, Patrícia V.; Santo, Daniela; De Bon, Francesco; Faneca, Henrique; Guliashvili, Tamaz; Coelho, Jorge F.J.; Serra, Arménio C.. "Expanding the use of affordable CuSO4·5H2O in ATRP techniques in homogeneous media". Polymer 241 (2022): 124526-124534. http://dx.doi.org/10.1016/j.polymer.2022.124526.
    10.1016/j.polymer.2022.124526
  10. Azevedo, Alexandro; Farinha, Dina; Geraldes, Carlos; Faneca, Henrique (4E1F-D234-7CD6). Corresponding author: Faneca, Henrique (4E1F-D234-7CD6). "Combining gene therapy with other therapeutic strategies and imaging agents for cancer theranostics". International Journal of Pharmaceutics 606 (2021): 120905-120928. http://dx.doi.org/10.1016/j.ijpharm.2021.120905.
    Published • 10.1016/j.ijpharm.2021.120905
  11. Farinha, Dina; Michael Migawa; Sarmento-Ribeiro, AB; Faneca, Henrique. Corresponding author: Faneca, Henrique. "A Combined Antitumor Strategy Mediated by a New Targeted Nanosystem to Hepatocellular Carcinoma". International Journal of Nanomedicine 16 (2021): 3385-3405. https://doi.org/10.2147/IJN.S302288.
    Open access • Published • 10.2147/IJN.S302288
  12. Faneca, Henrique. Corresponding author: Faneca, Henrique. "Non-Viral Gene Delivery Systems". Pharmaceutics 13 04 (2021): 446-449. https://doi.org/10.3390/ pharmaceutics13040446.
    Published • 10.3390/pharmaceutics13040446
  13. Costa, Diana; Santo, Daniela; Domingues, Cátia; Veiga, Francisco; Faneca, Henrique (4E1F-D234-7CD6); Figueiras, Ana. Corresponding author: Faneca, Henrique (4E1F-D234-7CD6). "Recent advances in peptide-targeted micelleplexes: Current developments and future perspectives". International Journal of Pharmaceutics 597 (2021): 120362-120382. https://doi.org/10.1016/j.ijpharm.2021.120362.
    Published • 10.1016/j.ijpharm.2021.120362
  14. Carvalho, Ana Maria; Cordeiro, Rosemeyre A.; Faneca, Henrique (4E1F-D234-7CD6). Corresponding author: Faneca, Henrique (4E1F-D234-7CD6). "Silica-Based Gene Delivery Systems: From Design to Therapeutic Applications". Pharmaceutics 12 7 (2020): 649-694. http://dx.doi.org/10.3390/pharmaceutics12070649.
    Published • 10.3390/pharmaceutics12070649
  15. Vaz-Ramos, Joana; Cordeiro, Rosemeyre; Castro, M. Margarida C.A.; Geraldes, Carlos F.G.C.; Costa, Benilde F.O.; Faneca, Henrique (4E1F-D234-7CD6); Durães, Luísa. "Supercritically dried superparamagnetic mesoporous silica nanoparticles for cancer theranostics". Materials Science and Engineering: C 115 (2020): 111124-111138. http://dx.doi.org/10.1016/j.msec.2020.111124.
    Published • 10.1016/j.msec.2020.111124
  16. Rosemeyre A. Cordeiro; Arménio Serra; Jorge F.J. Coelho; Faneca, Henrique (4E1F-D234-7CD6). Corresponding author: Faneca, Henrique (4E1F-D234-7CD6). "Poly(ß-amino ester)-based gene delivery systems: From discovery to therapeutic applications". Journal of Controlled Release 310 (2019): 155-187. https://doi.org/10.1016/j.jconrel.2019.08.024.
    Published • 10.1016/j.jconrel.2019.08.024
  17. Marina Matos; Rosemeyre A. Cordeiro; Faneca, Henrique; Jorge Coelho; Armando Silvestre; Andreia Sousa. "Replacing di(2-ethylhexyl) terephthalate by di(2-ethylhexyl) 2,5-furandicarboxylate for PVC plasticization: synthesis, materials preparation and characterization". Materials 12 14 (2019): 2336. http://dx.doi.org/10.3390/ma12142336.
    Published • 10.3390/ma12142336
  18. Daniela Santo; Patrícia V. Mendonça; Mafalda S. Lima; Rosemeyre A. Cordeiro; Luis Cabanas; Arménio Serra; Jorge F.J. Coelho; Faneca, Henrique (4E1F-D234-7CD6). Corresponding author: Faneca, Henrique (4E1F-D234-7CD6). "Poly(ethylene glycol)-block-poly(2-aminoethyl methacrylate hydrochloride)-based polyplexes as serum-tolerant nanosystems for enhanced gene delivery". Molecular Pharmaceutics 16 5 (2019): 2129-2141. https://doi.org/10.1021/acs.molpharmaceut.9b00101.
    Published • 10.1021/acs.molpharmaceut.9b00101
  19. Edna Soares; Rosemeyre Cordeiro; Henrique Faneca; Olga Borges. "Polymeric nanoengineered HBsAg DNA vaccine designed in combination with ß-glucan". International Journal of Biological Macromolecules 122 (2019): 930-939. https://doi.org/10.1016/j.ijbiomac.2018.11.024.
    Published • 10.1016/j.ijbiomac.2018.11.024
  20. Cordeiro, R.A.; Santo, D.; Farinha, D.; Serra, A.; Faneca, Henrique (4E1F-D234-7CD6); Coelho, J.F.J.. Corresponding author: Faneca, Henrique (4E1F-D234-7CD6). "High transfection efficiency promoted by tailor-made cationic tri-block copolymer-based nanoparticles". Acta Biomaterialia 47 (2017): 113-123. https://doi.org/10.1016/j.actbio.2016.10.015.
    Published • 10.1016/j.actbio.2016.10.015
  21. Santo, D.; Cordeiro, R.A.; Sousa, A.; Serra, A.; Coelho, J.F.J.; Faneca, Henrique (4E1F-D234-7CD6). Corresponding author: Faneca, Henrique (4E1F-D234-7CD6). "Combination of poly[(2-dimethylamino)ethyl methacrylate] and poly(ß-amino ester) results in a strong and synergistic transfection activity". Biomacromolecules 18 10 (2017): 3331-3342. https://doi.org/10.1021/acs.biomac.7b00983.
    Published • 10.1021/acs.biomac.7b00983
  22. Passadouro, M.; Faneca, Henrique (4E1F-D234-7CD6). Corresponding author: Faneca, Henrique (4E1F-D234-7CD6). "Managing pancreatic adenocarcinoma: A special focus in microRNA gene therapy". International Journal of Molecular Sciences 17 5 (2016): 718. https://doi.org/10.3390/ijms17050718.
    Published • 10.3390/ijms17050718
  23. Lebre, F.; Borchard, G.; Faneca, Henrique (4E1F-D234-7CD6); Pedroso De Lima, M.C.; Borges, O.. "Intranasal administration of novel chitosan nanoparticle/DNA complexes induces antibody response to hepatitis B surface antigen in mice". Molecular Pharmaceutics 13 2 (2016): 472-482. https://doi.org/10.1021/acs.molpharmaceut.5b00707.
    Published • 10.1021/acs.molpharmaceut.5b00707
  24. Deus, C.M.; Santos, G.L.; Loureiro, R.; Vega-Naredo, I.; Faneca, H.; Oliveira, P.J.. "Shutting down the furnace: preferential killing of cancer cells with mitochondrial-targeting molecules". Current Medicinal Chemistry 22 20 (2015): 2438-2457. http://www.eurekaselect.com/128348/article.
    Published • 10.2174/0929867322666150209155957
  25. Cordeiro, R.A.; Farinha, D.; Rocha, N.; Serra, A.C.; Faneca, Henrique (4E1F-D234-7CD6); Coelho, J.F.J.. Corresponding author: Faneca, Henrique (4E1F-D234-7CD6). "Novel cationic triblock copolymer of poly[2-(dimethylamino)ethyl methacrylate]-block-poly(ß-amino ester)-block-poly[2-(dimethylamino)ethyl methacrylate]: A promising non-viral gene delivery system". Macromolecular Bioscience 15 2 (2015): 215-228. https://doi.org/10.1002/mabi.201400424.
    Published • 10.1002/mabi.201400424
  26. Magalhães, M.; Farinha, D.; Pedroso de Lima, M.C.; Faneca, Henrique (4E1F-D234-7CD6). Corresponding author: Faneca, Henrique (4E1F-D234-7CD6). "Increased gene delivery efficiency and specificity of a lipid-based nanosystem incorporating a glycolipid". International journal of nanomedicine 9 (2014): 4979-4989. https://www.dovepress.com/increased-gene-delivery-efficiency-and-specificity-of-a-lipid-based-na-peer-reviewed-article-IJN.
    Published • 10.2147/IJN.S69822
  27. Gonçalves, F.A.; Costa, C.S.; Fabela, I.G.; Farinha, D.; Faneca, H.; Simões, P.N.; Serra, A.C.; Bártolo, P.J.; Coelho, J.F.. "3D printing of new biobased unsaturated polyesters by microstereo-thermallithography". Biofabrication 6 3 (2014): https://iopscience.iop.org/article/10.1088/1758-5082/6/3/035024.
    Published • 10.1088/1758-5082/6/3/035024
  28. Farinha, D.; Pedroso De Lima, M.C.; Faneca, Henrique (4E1F-D234-7CD6). Corresponding author: Faneca, Henrique (4E1F-D234-7CD6). "Specific and efficient gene delivery mediated by an asialofetuin-associated nanosystem". International Journal of Pharmaceutics 473 1-2 (2014): 366-374. https://doi.org/10.1016/j.ijpharm.2014.07.019.
    Published • 10.1016/j.ijpharm.2014.07.019
  29. Passadouro, M.; Pedroso de Lima, M.C.; Faneca, Henrique (4E1F-D234-7CD6). Corresponding author: Faneca, Henrique (4E1F-D234-7CD6). "MicroRNA modulation combined with sunitinib as a novel therapeutic strategy for pancreatic cancer". International Journal of Nanomedicine 9 1 (2014): 3203-3217. https://www.dovepress.com/microrna-modulation-combined-with-sunitinib-as-a-novel-therapeutic-str-peer-reviewed-article-IJN.
    Published • 10.2147/IJN.S64456
  30. Pinho, S.L.C.; Faneca, H.; Geraldes, C.F.G.C.; Delville, M.-H.; Carlos, L.D.; Rocha, J.. "Lanthanide-DTPA grafted silica nanoparticles as bimodal-imaging contrast agents". Biomaterials 33 3 (2012): 925-935. https://doi.org/10.1016/j.biomaterials.2011.09.086.
    Published • 10.1016/j.biomaterials.2011.09.086
  31. Duarte, S.; Loubat, A.; Momier, D.; Topi, M.; Faneca, H.; Pedroso De Lima, M.C.; Carle, G.F.; Pierrefite-Carle, V.. "Isolation of head and neck squamous carcinoma cancer stem-like cells in a syngeneic mouse model and analysis of hypoxia effect". Oncology Reports 28 3 (2012): 1057-1062. https://doi.org/10.3892/or.2012.1904.
    Published • 10.3892/or.2012.1904
  32. Duarte, S.; Faneca, H.; Lima, M.C.P.D.. "Folate-associated lipoplexes mediate efficient gene delivery and potent antitumoral activity in vitro and in vivo". International Journal of Pharmaceutics 423 2 (2012): 365-377. hhttps://doi.org/10.1016/j.ijpharm.2011.12.035.
    Published • 10.1016/j.ijpharm.2011.12.035
  33. Duarte, S.; Carle, G.; Faneca, H.; Lima, M.C.P.D.; Pierrefite-Carle, V.. "Suicide gene therapy in cancer: Where do we stand now?". Cancer Letters 324 2 (2012): 160-170. https://doi.org/10.1016/j.canlet.2012.05.023.
    Published • 10.1016/j.canlet.2012.05.023
  34. Pinho, S.L.C.; Faneca, H.; Geraldes, C.F.G.C.; Rocha, J.; Carlos, L.D.; Delville, M.-H.. "Silica nanoparticles for bimodal MRI-optical imaging by grafting Gd3+ and Eu3+/Tb3+ complexes". European Journal of Inorganic Chemistry 16 (2012): 2828-2837. https://doi.org/10.1002/ejic.201101110.
    Published • 10.1002/ejic.201101110
  35. Ana M Cardoso; Faneca, Henrique; João Almeida; Alberto Pais; Eduardo Marques; Maria Pedroso Lima; Amália Jurado. "Gemini surfactant dimethylene-1,2-bis(tetradecyldimethylammonium bromide)-based gene vectors: A biophysical approach to transfection efficiency". Biochimica et Biophysica Acta (BBA) - Biomembranes (2011): http://dx.doi.org/10.1016/j.bbamem.2010.09.026.
    Published • 10.1016/j.bbamem.2010.09.026
  36. Lundberg, D.; Faneca, H.; Pedroso De Lima, M.C.; Miguel, M.D.G.; Lindman, B.. "Inclusion of a single-tail amino acid-based amphiphile in a lipoplex formulation: effects on transfection efficiency and physicochemical properties". Molecular Membrane Biology 28 1 (2011): 42-53. https://doi.org/10.3109/09687688.2010.508879.
    Published • 10.3109/09687688.2010.508879
  37. Moura, M.J.; Faneca, H.; Lima, M.P.; Gil, M.H.; Figueiredo, M.M.. "In situ forming chitosan hydrogels prepared via ionic/covalent co-cross-linking". Biomacromolecules 12 9 (2011): 3275-3284. https://doi.org/10.1021/bm200731x.
    Published • 10.1021/bm200731x
  38. Almeida, J.A.S.; Faneca, H.; Carvalho, R.A.; Marques, E.F.; Pais, A.A.C.C.. "Dicationic alkylammonium bromide gemini surfactants. membrane perturbation and skin irritation". PLoS ONE 6 11 (2011): https://doi.org/10.1371/journal.pone.0026965.
    Published • 10.1371/journal.pone.0026965
  39. Duarte, S.; Faneca, H.; Pedroso De Lima, M.C.. "Non-covalent association of folate to lipoplexes: a promising strategy to improve gene delivery in the presence of serum". Journal of Controlled Release 149 3 (2011): 264-272. https://doi.org/10.1016/j.jconrel.2010.10.032.
    Published • 10.1016/j.jconrel.2010.10.032
  40. Passadouro, M.; Metelo, A.M.; Melão, A.S.; Pedro, J.R.; Faneca, H.; Carvalho, E.; Castro, M.M.C.A.. "Study of the antidiabetic capacity of the VO(dmpp)2 complex". Journal of Inorganic Biochemistry 104 9 (2010): 987-992. https://doi.org/10.1016/j.jinorgbio.2010.05.004.
    Published • 10.1016/j.jinorgbio.2010.05.004
  41. Silva-Lucca, R.A.; Faneca, H.M.S.; de Lima, M.C.P.; De Caroli, F.P.; Assis, M.L.; Sampaio, M.U.; Oliva, M.L.V.. "Interaction of proteinase inhibitors with phospholipid vesicles is modulated by pH". International Journal of Biological Macromolecules 47 4 (2010): 551-557. https://doi.org/10.1016/j.ijbiomac.2010.07.011.
    Published • 10.1016/j.ijbiomac.2010.07.011
  42. Faneca, H.; Figueiredo, V.A.; Tomaz, I.; Gonçalves, G.; Avecilla, F.; Pedroso de Lima, M.C.; Geraldes, C.F.G.C.; Pessoa, J.C.; Castro, M.M.C.A.. "Vanadium compounds as therapeutic agents: some chemical and biochemical studies". Journal of Inorganic Biochemistry 103 4 (2009): 601-608. https://doi.org/10.1016/j.jinorgbio.2008.11.004.
    Published • 10.1016/j.jinorgbio.2008.11.004
  43. Neves, S.; Faneca, H.; Bertin, S.; Konopka, K.; Düzgünes, N.; Pierrefite-Carle, V.; Simões, S.; Pedroso De Lima, M.C.. "Transferrin lipoplex-mediated suicide gene therapy of oral squamous cell carcinoma in an immunocompetent murine model and mechanisms involved in the antitumoral response". Cancer Gene Therapy 16 1 (2009): 91-101. hhttps://doi.org/10.1038/cgt.2008.60.
    Published • 10.1038/cgt.2008.60
  44. Sara Trabulo; Miguel Mano; Faneca, Henrique; Ana L Cardoso; Sónia Duarte; Ana Henriques; Artur Paiva; et al. "S413-PV cell penetrating peptide and cationic liposomes act synergistically to mediate intracellular delivery of plasmid DNA". The Journal of Gene Medicine 10 11 (2008): 1210-1222. https://doi.org/10.1002/jgm.1247.
    Published • 10.1002/jgm.1247
  45. Faneca, H.; Faustino, A.; Pedroso de Lima, M.C.. "Synergistic antitumoral effect of vinblastine and HSV-Tk/GCV gene therapy mediated by albumin-associated cationic liposomes". Journal of Controlled Release 126 2 (2008): 175-184. https://doi.org/10.1016/j.jconrel.2007.12.005.
    Published • 10.1016/j.jconrel.2007.12.005
  46. Faneca, H.; Cabrita, A.S.; Simões, S.; Pedroso de Lima, M.C.. "Evaluation of the antitumoral effect mediated by IL-12 and HSV-tk genes when delivered by a novel lipid-based system". Biochimica et Biophysica Acta - Biomembranes 1768 5 (2007): 1093-1102. https://doi.org/10.1016/j.bbamem.2006.12.017.
    Published • 10.1016/j.bbamem.2006.12.017
  47. Simões, S.; Filipe, A.; Faneca, H.; Mano, M.; Penacho, N.; Düzgünes, N.; de Lima, M.P.. "Cationic liposomes for gene delivery". Expert Opinion on Drug Delivery 2 2 (2005): 237-254. https://doi.org/10.1517/17425247.2.2.237.
    Published • 10.1517/17425247.2.2.237
  48. Faneca, H.; Simões, S.; Pedroso de Lima, M.C.. "Association of albumin or protamine to lipoplexes: enhancement of transfection and resistance to serum". Journal of Gene Medicine 6 6 (2004): 681-692. https://doi.org/10.1002/jgm.550.
    Published • 10.1002/jgm.550
  49. Simões, S.; Fonseca, C.; Faneca, H.; Düzgünes, N.; Pedroso de Lima, M.C.. "Protein-associated lipoplexes: Novel strategies to enhance gene delivery mediated by lipid-based particles". S.T.P. Pharma Sciences 12 6 (2002): 339-344. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036855226&partnerID=MN8TOARS.
    Published
  50. Faneca, H.; Simões, S.; Pedroso de Lima, M.C.. "Evaluation of lipid-based reagents to mediate intracellular gene delivery". Biochimica et Biophysica Acta - Biomembranes 1567 SUPPL. (2002): 23-33. https://doi.org/10.1016/S0005-2736(02)00545-X.
    Published • 10.1016/S0005-2736(02)00545-X
  51. Pedroso De Lima, M.C.; Simões, S.; Pires, P.; Faneca, H.; Düzgünes, N.. "Cationic lipid-DNA complexes in gene delivery: from biophysics to biological applications". Advanced Drug Delivery Reviews 47 2-3 (2001): 277-294. https://doi.org/10.1016/S0169-409X(01)00110-7.
    Published • 10.1016/S0169-409X(01)00110-7
Journal issue
  1. Faneca, Henrique. "Special Issue "Non-Viral Gene Delivery Systems (Volume II)"". Pharmaceutics (2022): https://www.mdpi.com/si/pharmaceutics/nonviral_gene_delivery_II.
    Invited editor
  2. "Special Issue "Non-Viral Gene Delivery Systems"". Pharmaceutics (2020): https://www.mdpi.com/si/pharmaceutics/nonviral_gene_delivery.
    Invited editor
Thesis / Dissertation
  1. Faneca, Henrique. "New lipid-based systems for application in antitumoral gene therapy". PhD, Universidade de Coimbra, 2005. http://hdl.handle.net/10316/2083.
  2. Faneca, Henrique. "Development of novel liposome formulations for transport and intracellular delivery of genetic material". Master, Universidade de Coimbra, 2001.