Maria Rita Ventura (4F10-523D-FFB9)

Curriculum Vitae

Maria Rita Ventura

Rita Ventura is the head of the Bioorganic Chemistry Laboratory at ITQB NOVA since October 2005. Her main research interests are asymmetric synthesis, the total synthesis of natural compounds and analogues with improved biological properties, carbohydrate chemistry, stereoselective organocatalysis, biocatalysis and medicinal chemistry. R. Ventura’s Lab main research aim is to synthesise biologically active molecules, to modify their structure in order to enhance or modulate their biological properties and to contribute to the understanding of the biological phenomena in which they play a crucial role. This knowledge is important for the design and synthesis of new molecules that can interfere with the molecular mechanisms responsible for pathogenic behaviours, with potential innovative therapeutic applications. R. Ventura obtained a PhD degree in Chemistry from Universidade NOVA de Lisboa in 1999 and graduated in Pharmaceutical Sciences, Faculdade de Farmácia da Universidade de Lisboa in 1995. R. Ventura has published 71 research articles in peer-reviewed journals, 2 book chapters and 5 patents (Scopus Author ID: 7201763165, ResearcherID B-8011-2008, Orcid 0000-0002-6854-7278). She is the author and co-author of over 120 oral and poster communications in international conferences. She has received 4 prizes. R. Ventura is currently supervising 7 PhD students, co-supervising 3 PhD students (Supervisor of the Organic Synthesis tasks), 1 Doctorated researcher (Marie Curie Grant), 2 Research Fellows (BI). She has already supervised 4 PhD Students (1 Marie Curie fellow), 8 Post-doc researchers (1 ERA Postdoctoral Fellow, Seal of Excellence award), 9 Master Students and several final year project students, Erasmus students, Leonardo da Vinci exchange students, technician students and Summer School students. R. Ventura is currently PI of 1 FCT project and of an European Stroke Research Foundation (ESRF) project and team member (Leader of the organic synthesis tasks) of 3 other projects. She has been the PI of 2 FCT projects, Co-PI and team member of 2 European projects, of 16 national research projects funded by FCT and one by Hovione, that led to an international patent. R. Ventura coordinates the curricular unit Drug Discovery, Design and Development of the Master in Biochemistry for Health (ITQB, FCT, NMS NOVA) since 2014 and is the coordinator of the curricular unit Biological Chemistry in the Doctoral program Molecular Biological Sciences (ITQB NOVA). She has coordinated 3 curricular units in Master courses and has taught in 3 Doctoral Programs and she has coordinated 2 curricular units of pre-graduated courses. R. Ventura participates regularly in Science Communication activities promoted by ITQB such as the ITQB open day and receiving school visits, writing articles for newspapers, TV and newspaper interviews. R. Ventura was co-founder and CSO of the startup Extremochem, 2013-2023. Part of the research is patented (International patent WO2015137838A1). Extremochem employed young and talented researchers and has attracted private venture capital. It was sold to Hovione in 2023, being renamed Hovione-Extremochem.

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Identification

Personal identification

Full name: Maria Rita Ventura
Date of birth: 1971/06/19
Gender: Female

Citation names

Ventura, M. Rita
R. Ventura
M. Rita Ventura
Rita Ventura

Author identifiers

Ciência ID: 4F10-523D-FFB9
ORCID iD: 0000-0002-6854-7278
Researcher Id: B-8011-2008
Scopus Author Id: 7201763165

Email addresses

rventura@itqb.unl.pt (Professional)

Telephones

Telephone

214469775 (Professional)

Addresses

Universidade Nova de Lisboa - Instituto de Tecnologia Química e Biológica António Xavier. ITQB-NOVA, Av. da Republica, Apartado 127, 2780-157, Oeiras, Oeiras, Portugal (Professional)

Websites

http://www.itqb.unl.pt/research/chemistry/bioorganic-chemistry (Professional)

Knowledge fields

Exact Sciences - Chemical Sciences
Exact Sciences - Chemical Sciences - Organic Chemistry
Medical and Health Sciences - Basic Medicine - Medicinal Chemistry

Languages

Language	Speaking	Reading	Writing	Listening	Peer-review
English	Proficiency (C2)	Proficiency (C2)	Proficiency (C2)	Proficiency (C2)	Proficiency (C2)
French	Advanced (C1)	Proficiency (C2)	Proficiency (C2)	Proficiency (C2)	Proficiency (C2)
Portuguese (Mother tongue)

Education

	Degree	Classification
1995/04/01 - 1999/05/03 Concluded	Doutoramento em Química (Doutoramento) Major in Química Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal "The Asymmetric Syntheses of Natural Compounds Starting from (-)-Quinic Acid" (THESIS/DISSERTATION)	Aprovada por Unanimidade
1995 Concluded	Ciências Farmacêuticas (Licenciatura) Universidade de Lisboa Faculdade de Farmácia, Portugal "Estágio profissional em Farmácia de Oficina e em Hospital" (THESIS/DISSERTATION)	17 (of a maximum of 20)

Affiliation

Science

	Category Host institution	Employer
2016/04/01 - Current	Auxiliary Researcher (Research)	Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
	Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2015/01/01 - 2016/03/31	Researcher (Research)	Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal

2005/10/01 - 2014/12/31	Auxiliary Researcher (Research)	Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal

2002/09/01 - 2005/09/30	Postdoc (Research)	Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
	Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
1999/05/01 - 2002/04/30	Postdoc (Research)	Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
	Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Teaching in Higher Education

	Category Host institution	Employer
2022/01/01 - 2023/12/31	Invited Assistant Professor (University Teacher)	Universidade do Algarve, Portugal
	Universidade do Algarve Departamento de Ciências Biomédicas e Medicina, Portugal

Projects

Grant

	Designation	Funders
2022/01/01 - 2023/06/30	Nose to Brain delivery of Bryologs: a potential Fast Acting Stroke Treatment - Principal Investigator NBB-Fast Principal investigator Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal	European Stroke Research Foundation ESRF Ongoing
2009/10 - 2010/10	Synthesis of sugar derivatives for protein stabilisation studies 034/BII/2009 Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica António Xavier, Portugal	Fundação para a Ciência e a Tecnologia Concluded

Contract

	Designation	Funders
2018/01 - Current	PRARHITAZ - Prevenção da Artrite Reumatóide: Suplemento de hidroxitirosol em azeite refinado. - Team member responsible for the organic synthesis tasks Projecto 574 IBET	N/A
2023/03/12 - 2026/03/11	Broadening the spectrum of biocatalysts, bioprocesses and bio-products in industrial biotechnology - Team member responsible for the organic synthesis tasks 2022.02027.PTDC Researcher Universidade Nova de Lisboa, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2023/03/01 - 2026/02/28	Glycofoldamers as bacterial toxin inhibitors - Team member responsible for the organic synthesis tasks 2022.03561.PTDC Researcher Universidade Nova de Lisboa, Portugal Associação para a Inovação e Desenvolvimento da FCT, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2023/01/01 - 2025/12/31	Modelling vitamins B1 and B2 biosynthesis and biofortification in rice - Team member responsible for the organic synthesis tasks 2022.02916.PTDC Researcher Universidade Nova de Lisboa, Portugal Instituto Nacional de Saúde Doutor Ricardo Jorge, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2021/01/01 - 2025/12/31	Ciências da Vida para um Futuro Saudável e Sustentável LA/P/0087/2020 10.54499/LA/P/0087/2020 Universidade Nova de Lisboa Microbiologia Molecular Estrutural e Celular, Portugal Instituto Português de Oncologia de Lisboa Francisco Gentil EPE, Portugal Instituto Gulbenkian de Ciência, Portugal Instituto de Biologia Experimental e Tecnológica, Portugal Universidade de Lisboa Centro de Estudos Comparatistas, Portugal BioResources 4 Sustainability, Portugal Universidade de Trás-os-Montes e Alto Douro Centro de Investigação e de Tecnologias Agro-Ambientais e Biologicas, Portugal Universidade NOVA de Lisboa, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2021/03/01 - 2024/02/29	Biocatalytic synthesis of oligoarabinosides for the study of drug targets and development of novel anti-tuberculosis drugs - Principal Investigator PTDC/BIA-BQM/4056/2020 Principal investigator Universidade Nova de Lisboa, Portugal Universidade Nova de Lisboa Microbiologia Molecular Estrutural e Celular, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2021/01/01 - 2022/12/31	Biofactories for high value natural pigments: the production of carotenoids in plant cell cultures. Co-PI, Responsible for the organic synthesis tasks. InnOValley Proof of Concept Fund 2021 Co-Principal Investigator (Co-PI)
2018 - 2022	Membrane protein integrated technologies development for drug design (ProMeTeus) Project N. 823780, H2020, Call H2020-MSCA-RISE-2018. Researcher Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal	Horizon 2020 Framework Programme (H2020) Ongoing
2018/10/01 - 2021/09/30	Deciphering the mechanisms of interspecies bacterial communication towards the manipulation of the mammalian gut microbiota (AI-2 Probes) - Principal Investigator. PTDC/BIA-BQM/29668/2017 Principal investigator Universidade Nova de Lisboa, Portugal Fundação Calouste Gulbenkian, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2018/10/01 - 2021/09/30	Identification of novel quorum sensing signals in the mammalian gut microbiota (GUTSensing) - Team member responsible for the organic synthesis tasks PTDC/BIA-MIC/30487/2017 Researcher Fundação Calouste Gulbenkian, Portugal Universidade Nova de Lisboa, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2018/10/01 - 2021/09/30	Molecular and cell biology of imipenem resistance in the human enteric pathogen Clostridium difficile - Team member responsible for the organic synthesis tasks PTDC/BIA-MIC/32542/2017 Researcher Universidade Nova de Lisboa, Portugal Associação para a Inovação e Desenvolvimento da FCT, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2018/10/01 - 2021/09/30	Unravelling the structure of membrane proteins involved in mycobacteria cell wall biosynthesis to develop novel anti-tuberculosis drugs and better understand resistance mechanisms - Team member responsible for the organic synthesis tasks PTDC/BIA-BQM/30421/2017 Researcher Universidade Nova de Lisboa, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2020/06 - 2020/12	DETECT: Development of an Easy, fast-Track and Economical Colorimetric Test for autonomous national diagnosis of COVID-19 433 Researcher	Fundação para a Ciência e a Tecnologia Concluded
2019/01/01 - 2019/12/31	Molecular, Structural and Cellular Microbiology UID/CBQ/04612/2019 Universidade Nova de Lisboa, Portugal Universidade Nova de Lisboa Microbiologia Molecular Estrutural e Celular, Portugal Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica António Xavier, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2016/05/01 - 2019/04/30	An integrated systems approach to uncover the key players in complex protein N-glycosylation in Trypanosoma brucei - Team member responsible for the organic synthesis tasks PTDC/BBB-BSS/0827/2014 Researcher Instituto de Medicina Molecular, Portugal Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2013/07/01 - 2016/06/30	NMR Net - National Facility for Nuclear Magnetic Resonance: from Molecular Structure and Dynamics to Protein Function, Cell Physiology, and Metabolomics info:eu-repo/grantAgreement/FCT/3599-PPCDT/127013/PT Researcher Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal	Universidade do Algarve Faculdade de Ciências e Tecnologia Concluded
2015 - 2016	New organocatalysts for light activated asymmetric catalysis - Principal Investigator Química e Luz Principal investigator Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal	Fundação Calouste Gulbenkian Concluded
2013/05/01 - 2015/10/31	Epigenetic modulation of transgene expression in plant cell cultures for the improved production of recombinant proteins - Team member responsible for the organic synthesis tasks PTDC/BIA-PLA/2411/2012 Researcher Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2013/07/01 - 2015/09/30	Biosynthesis of rare methylmannose polysaccharides in nontuberculous mycobacteria - Team member responsible for the organic synthesis tasks PTDC/BIA-MIC/2779/2012 Researcher Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2011/03/01 - 2014/04/30	Studies on the structure/activity relationship of AI-2, a bacterial signalling molecule for inter-species communication - Principal Investigator PTDC/QUI-BIQ/113880/2009 Principal investigator Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2011 - 2012	Fluticasone Proof of Concept - Researcher Hovione Collaboration Researcher Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal	Concluded
2007/06/01 - 2011/03/31	In search of ideal protein stabilisers: compound libraries inspired by solutes from hyperthermophiles - Team member responsible for the organic synthesis tasks PTDC/BIO/70806/2006 Researcher Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2005/06/15 - 2007/08/14	Structural determinants of protein stabilization by compatible solutes from hyperthermophiles: in search of guidelines solute improvement POCI/BIA-PRO/57263/2004 Researcher Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal Universidade de Lisboa Instituto Superior Técnico, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2005/10/01 - 2007/07/01	Studies on the synthesis and application of 2-oxoaza[x.1.0]bicycles POCI/QUI/62794/2004 Researcher Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2001 - 2002	Synthesis of Compounds with Biological Activity Starting from Maleimides - Prize Awardee, Researcher Síntese Química Researcher Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal	Fundação Calouste Gulbenkian Concluded
1999 - 2002	Molecular basis of protein thermostabilisation by hypersolutes POCTI/BME/35131/99 Researcher Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal	Fundação para a Ciência e a Tecnologia Concluded
1999 - 2002	Development of New and Improved Processes for Palladium Catalysed Cross-Coupling Reactions for Natural products Synthesis POCTI/QUI/36536/99) Researcher	Fundação para a Ciência e a Tecnologia Concluded

Outputs

Publications

Book chapter	Maycock, Christopher D.; M. Rita Ventura. Corresponding author: M. Rita Ventura. "Approaches to Asymmetric Compounds Using Natural Products". In Synthesis and Applications in Chemistry and Materials, 359-401. WORLD SCIENTIFIC, 2024. Published • 10.1142/9789811283215_0022 Eva C. Lourenço; M. Rita Ventura. Corresponding author: M. Rita Ventura. "Recent advances in stereoselective 1,2-cis-glycosylation". In Carbohydrate Chemistry: Chemical and Biological Approaches Volume 46, 23-43. 2024. In press
Conference abstract	Carregosa, Diogo; Figueira, Inês; Bastos, Catarina; Pais, Teresa Faria; Ventura, M. Rita; Santos, Cláudia Nunes dos. "Polyphenol metabolites and derivatives: from diminishing neuroinflammation to increasing neuroprotection". Paper presented in 2nd International Conference on Food Bioactives & Health, Lisboa, 2018. Published Figueira, Inês; Garcia, Gonçalo; Pimpão, Rui Carlos; Costa, Inês; Tavares, Lucélia; Almeida, Andreia Filipa; Ventura, M. Rita; et al. "Crossing the blood-brain barrier: effects of human bioavailable (poly)phenol metabolites in neuronal cells". Paper presented in 7th ITQB NOVA PhD Students´ Meeting, Oeiras, 2016. Published Figueira, Inês; Pimpão, Rui Carlos; Garcia, Gonçalo; Tavares, Lucélia; Ventura, M. Rita; Terrasso, Ana Paula; Silva, Carina; et al. "Neuroprotective potential of phenolic sulfates, abundant bioavailable metabolites". Paper presented in 7th International Conference on Polyphenols and Health, Tours, 2015. Published Figueira, Inês; Pimpão, Rui Carlos; Garcia, Gonçalo; Tavares, Lucélia; Ventura, M. Rita; Terrasso, Ana Paula; Silva, Carina; et al. "Crossing the blood-brain barrier: unravelling beneficial effects of human bioavailable (poly)phenol metabolites". Paper presented in 9th World Congress on Polyphenols Applications, 2015. Published
Conference poster	RODRIGUES, MIGUEL; Carrau, Gonzalo; Kis, Peter; Karina B. Xavier; M. Rita Ventura. Corresponding author: M. Rita Ventura. "Development of AI-2 Chemical Probes for the Identification and Characterisation of Novel AI-2 Receptors". 2024. RODRIGUES, MIGUEL; António Ferreira; Maria Rosario Bronze; Karina B. Xavier; M. Rita Ventura. Corresponding author: M. Rita Ventura. "Quantification of quorum sensing signaling molecule autoinducer-2 in biological samples by GC-MS". Paper presented in 13º Encontro Nacional de Cromatografia, 2023. Almeida, Vanessa T.; Conceição, Cristiano; Zinkle, Allen; Liu, Yaqi; Issoglio, FM; Rodrigues, José; Brito, José A.; et al. Corresponding author: Almeida, Vanessa T.. "AftD as a new potential drug target to fight tuberculosis". Paper presented in 13th ITQB NOVA PhD Students Meeting, 2023. Kis, Peter; Miranda, Vanessa; RODRIGUES, MIGUEL; Karina B. Xavier; M. Rita Ventura. "The first synthesis of autoinducer-2 prodrugs". Paper presented in The 21st European Carbohydrate Symposium EUROCARB, 2023. Kis, Peter; Miranda, Vanessa; RODRIGUES, MIGUEL; Karina B. Xavier; M. Rita Ventura. "Chemoenzymatic strategy towards new autoinducer-2 prodrugs". Paper presented in 14th International Meeting of the Portuguese Carbohydrate Group - GLUPOR 14, 2023. Catarina Amaral; Sofia M. da Silva; W. Antunes; G. Duarte, Américo; E. Moe; Lima, Luís M. P.; N. A. Faria; et al. "From lab to field: low cost saliva tests for mass-screening of SARS-CoV-2". Paper presented in V International Conference NOVAhealth Chronic Disease and Infection, 2022. Marques, Daniela; Carecho, Rafael; Carregosa, Diogo; Diogo Moura-Louro; Ávila-Gálvez, María Ángeles; Domenico Masuero; Federica Tramer; et al. "Bioavailable Gut (Poly)Phenol Metabolites are Transported Across The Blood-Brain Barrier and Attenuate Brain Inflammation". Paper presented in 24th International Symposium on Signal Transduction At The Blood-Brain Barriers, 2022. Rénio, Márcia Alexandra dos Reis Ribeiro; Murtinho, Dina; Ventura, M. Rita. "Bifunctional 1,3-diamine organocatalysts derived from (+)-camphoric acid for asymmetric Michael addition of 1,3-dicarbonyl compounds to nitroolefins". Paper presented in XXII International Symposium on Homogeneous Catalysis (XXII ISHC), 2022. Rodrigues, Miguel; Carrau, Gonzalo; Karina B. Xavier; Ventura, M. Rita. "Design and synthesis of new Autoinducer-2 chemical probes". Paper presented in 22nd Tetrahedron Symposium 2022, 2022. Conceição, Cristiano; Issoglio, FM; Almeida, Vanessa T.; Rodrigues, José; Archer, Margarida; M. Rita Ventura. Corresponding author: Conceição, Cristiano. "Development of a new functional assay to study potential anti-tuberculosis drug targets - Arabinofuranosyltransferases". Paper presented in 12th ITQB NOVA PhD Students Meeting, 2022. Mendes, Aristides L.; Vaz da Silva, Zoé; Gonçalo Covas; Rita Ventura; Antunes Cordeiro, Tiago; Oleastro, Mónica; Monica Serrano; Filipe, Sérgio Raposo; Henriques, Adriano. "Identification of a novel MecA-like PBP in Clostridioides difficile involved in carbapenem resistance.". Paper presented in ClostPath 12, 2021. Martins, B.T.; Rocha, J.; Serra, A.T.; Silva, S.; Sepodes, B.; Mecha, E.; Fernandez, N.; et al. "Hydroxytyrosol-supplemented refined olive oil reduces paw edema in two animal models of arthritis". Paper presented in 12 Topics in Rheumatology, Lisboa, Portugal, 2020. Martins, B.T.; Rocha, J.; Figueira, M.E.; Serra, A.T.; Mecha, E.; Silva, S.; Matias, A.A.; et al. "Protective effects of hydroxytyrosol-supplemented refined olive oil in induced arthritis". Paper presented in 9th International Conference on Polyphenols and Health, Kobe, Japan, 2019. Martins, B.T.; Silva, S.; Mecha, E.; Serra, A.T.; Bronze, M.R.; Ventura, M. Rita. "Chemical synthesis of hydroxytyrosol, oleacein and oleocanthal". Paper presented in 9th International Conference on Polyphenols and Health, Kobe, Japan, 2019. Martins, B.T.; Duarte, N.; Silva, A.B.; Carrola, J.; Mota, J.; Ventura, M. Rita; Bronze, M.R.. "Development of a MS/MS spectral library of phenolic compounds using electrospray ionization and triple-quadrupole mass spectrometer". Paper presented in 1st Iberian meeting in separation sciences & mass spectrometry, Santiago de Compostela, Spain, 2019. Martins, B.T.; Silva, S.; Mecha, E.; Bronze, M.R.; Ventura, M. Rita. "An improved synthesis of hydroxytyrosol and its main metabolites". Paper presented in 13th World Congress on Polyphenols Applications, Valetta, Malta, 2019. A. L. Mendes; G. Covas; J. Isidro; R. Ventura; M. Oleastro; S. Filipe; M. Serrano; Serrano, M; A. O. Henriques. "Mechanisms of Carbapenem resistance in Clostridioides difficile.". Paper presented in Clostpath 11, 2019. Martins, B.T.; Serra, A.T; Silva, S.; Matias, A.; Rocha, J.; Ventura, M. Rita; Vidal, B.; et al. "Protective effects of hydroxytyrosol-supplemented refined olive oil in collagen-induced arthritis". Paper presented in 12 Topics in Rheumatology, Lisboa, Portugal, 2019. Martins, B.T.; Silva, S.; Bronze, M.R.; Ventura, M. Rita. "An efficient synthesis of hydroxytyrosol and its metabolites". Paper presented in 2nd International Conference on Food Bioactives and Health, Lisboa, Portugal, 2018. Tatiana Cereija; Susana Alarico; Eva C. Lourenço; M. Rita Ventura; Nuno Empadinhas; Pereira, Pedro J.B.. "Biochemical and structural characterization of a mycobacterial glucosylglycerate hydrolase, a key enzyme in nitrogen starvation recovery". Paper presented in XIX National Congress of Biochemistry, Guimarães, Portugal, 2016. Miranda, Vanessa; Inês M. Torcato; Karina B. Xavier; M. Rita Ventura. "Synthesis of prodrugs and chemical probes based on the structure of autoinducer-2". Paper presented in 7th ITQB-NOVA PhD Student's Meeting, 2016. Miranda, Vanessa; Inês M. Torcato; Karina B. Xavier; M. Rita Ventura. "Synthesis of prodrugs based on autoinducer-2 to manipulate the levels of AI-2 in the gut microbiota". Paper presented in XV Ed. BOSS, 2016. Mendes, Aristides L.; Rita Ventura; Serrano, M; Henriques, A.O.. "RNA mimics of GFP as transcriptional reporters in the human intestinal pathogen Clostridium difficile.". Paper presented in Nova Saúde Meeting, Lisbon, Portugal, 2015. Miranda, Vanessa; Inês M. Torcato; Stephen Miller; M. Rita Ventura; Karina B. Xavier. "Autoinducer-2 recognition by gut microbiota bacterial strains". Paper presented in MicroBiotec, 2015. Ana Maranha; Alarico, Susana; Mafalda Costa; Andreia Lamaroso; Daniela Nunes-Costa; Eva C. Lourenço; Rita Ventura; Vitor Mendes; Nuno Empadinhas. "The Early Steps In Mycobacterial MGLP Biosynthesis: The Players". Paper presented in Eurocarb 17 Symposyum, TelAviv, Israel, 2013. Alarico, Susana; Ana Maranha; Mafalda Costa; Eva C. Lourenço; Rita Ventura; Nuno Empadinhas. "The mycobacterial glucosylglycerate hydrolase is restricted to rapidly growing species". Paper presented in ICAR 2012: II International Conference on Antimicrobial Research, Lisboa, Portugal, 2012. João Carlos Marques; Rui Fabio; Osvaldo S. Ascenso; Karina B. Xavier; Christopher D. Maycock; Rita Ventura. "An efficient synthesis of AI-2 analogues, the signalling molecule for inter-species quorum sensing.". Paper presented in 4th International Symposium on Advances in Synthetic and Medicinal Chemistry, St. Petersburg, Russia., 2011. Nunes, Rafael S.; Lourenço, Eva C.; Ventura, M. Rita. "Synthesis of glycoside derived compatible solutes for protein stabilization". Paper presented in Ciência 2010 - Encontro com a Ciência e Tecnologia em Portugal, Lisboa, Portugal, 2010.
Journal article	Brissos, Vania; Renio, Marcia; Lejmel, Magdalena; Estevinho, Ricardo; Robalo, M. Paula; Ventura, M. Rita; Martins, Lígia O.. "Unlocking Lignin's Potential: Engineered Bacterial Laccases to Produce Biologically Active Molecules". ChemSusChem (2024): http://dx.doi.org/10.1002/cssc.202401386. 10.1002/cssc.202401386 Rénio, Márcia; Ventura, Maria Rita. Corresponding author: Ventura, Maria Rita. "Synthesis of Mono- And Bis-Thiourea Organocatalysts and Their Application in Stereoselective Glycosylation Reactions". ChemCatChem (2024): http://dx.doi.org/10.1002/cctc.202401227. 10.1002/cctc.202401227 Rafael Carecho; Daniela Marques; Diogo Carregosa; Domenico Masuero; Mar Garcia-Aloy; Federica Tramer; Sabina Passamonti; et al. "Circulating low-molecular-weight (poly)phenol metabolites in the brain: unveiling in vitro and in vivo blood–brain barrier transport". Food & Function (2024): https://doi.org/10.1039/D4FO01396D. 10.1039/D4FO01396D RODRIGUES, MIGUEL; António Ferreira; Maria Ramirez-Montoya; A. Oliveira, Rita; Kis, Peter; Cabral, Vitor; Maria Rosario Bronze; Karina B. Xavier; M. Rita Ventura. Corresponding author: M. Rita Ventura. "Submitted - Manipulation and Quantification of the Levels of Autoinducer-2 Quorum Sensing Signal in the Mouse Gut". (2024): Submitted Paulo Durão; Peter Kis; Ivo M. Chelo; M. Rita Ventura; Lígia O. Martins. "Environmentally Friendly Degradation and Detoxification of Rifampicin by a Bacterial Laccase and Hydrogen Peroxide". ChemBioChem (2023): https://doi.org/10.1002/cbic.202300627. 10.1002/cbic.202300627 André Taborda; Tomás Frazão; Miguel V. Rodrigues; Xavier Fernández-Luengo; Ferran Sancho; Maria Fátima Lucas; Carlos Frazão; et al. "Mechanistic insights into glycoside 3-oxidases involved in C-glycoside metabolism in soil microorganisms". Nature Communications (2023): https://doi.org/10.1038/s41467-023-42000-3. 10.1038/s41467-023-42000-3 Maranha, Ana; Costa, Mafalda; Ripoll-Rozada, Jorge; Manso, José A.; Miranda, Vanessa; Mendes, Vera M.; Manadas, Bruno; et al. "Self-recycling and partially conservative replication of mycobacterial methylmannose polysaccharides". Communications Biology 6 1 (2023): http://dx.doi.org/10.1038/s42003-023-04448-3. Published • 10.1038/s42003-023-04448-3 Rodrigues, Miguel V.; Kis, Peter; Xavier, Karina B.; M. Rita Ventura. "Synthesis and potential of Autoinducer-2 and analogs to manipulate inter-species Quorum Sensing". Israel Journal of Chemistry (2023): http://dx.doi.org/10.1002/ijch.202200091. Published • 10.1002/ijch.202200091 Martins, Beatriz T.; Bronze, Maria Rosário; M. Rita Ventura. "Phenolic Compounds from Virgin Olive Oil: Approaches for Their Synthesis and Analogues". Journal of Agricultural and Food Chemistry 70 44 (2022): 14109-14128. http://dx.doi.org/10.1021/acs.jafc.2c05349. Published • 10.1021/acs.jafc.2c05349 Márcia Rénio; Dina Murtinho; M. Rita Ventura. Corresponding author: M. Rita Ventura. "New bifunctional 1,3-diamine organocatalysts derived from (+)-camphoric acid for asymmetric Michael addition of 1,3-dicarbonyl compounds to nitroolefins". Chirality (2022): https://doi.org/10.1002/chir.23424. 10.1002/chir.23424 Piccinini, Astra; Lourenço, Eva C.; Ascenso, Osvaldo S.; Ventura, Maria Rita; Amenitsch, Heinz; Moretti, Paolo; Mariani, Paolo; Ortore, Maria Grazia; Spinozzi, Francesco. "SAXS Reveals the Stabilization Effects of Modified Sugars on Model Proteins". Life 12 1 (2022): 123. http://dx.doi.org/10.3390/life12010123. 10.3390/life12010123 Amaral, Catarina; Antunes, Wilson; Moe, Elin; Duarte, Américo G.; Lima, Luís M. P.; Santos, Cristiana; Gomes, Inês L.; et al. "A molecular test based on RT-LAMP for rapid, sensitive and inexpensive colorimetric detection of SARS-CoV-2 in clinical samples". Scientific Reports 11 1 (2021): 16430. http://dx.doi.org/10.1038/s41598-021-95799-6. Open access • Published • 10.1038/s41598-021-95799-6 Osvaldo S. Ascenso; Gonzalo Carrau; Karina B. Xavier; M. Rita Ventura; Christopher D. Maycock. "An Efficient Synthesis of Optically Active [4-13C] Labelled Quorum Sensing Signal Autoinducer-2". Molecules 26 2 (2021): 369-369. https://doi.org/10.3390/molecules26020369. 10.3390/molecules26020369 Rebelo, Bárbara A.; Farrona, Sara; Ventura, M. Rita; Abranches, Rita. "Canthaxanthin, a Red-Hot Carotenoid: Applications, Synthesis, and Biosynthetic Evolution". Plants 9 8 (2020): 1039. http://dx.doi.org/10.3390/plants9081039. Published • 10.3390/plants9081039 Rebelo, B.A.; Santos, R.B.; Ascenso, O.S.; Nogueira, A.C.; Lousa, D.; Abranches, R.; Ventura, M.R.. "Synthesis and biological effects of small molecule enhancers for improved recombinant protein production in plant cell cultures". Bioorganic Chemistry 94 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85076599041&partnerID=MN8TOARS. 10.1016/j.bioorg.2019.103452 Ventura, M. Rita; Tatiana Barros Cereija; Susana Alarico; Eva C. Lourenço; José António Manso; M. Rita Ventura; Nuno Empadinhas; Sandra Macedo-Ribeiro; Pedro José Barbosa Pereira. "The structural characterization of a glucosylglycerate hydrolase provides insights into the molecular mechanism of mycobacterial recovery from nitrogen starvation". IUCrJ 6 4 (2019): 572-585. https://doi.org/10.1107/S2052252519005372. 10.1107/S2052252519005372 Jorge Ripoll-Rozada; Mafalda Costa; José A. Manso; Ana Maranha; Vanessa Miranda; André Sequeira; M. Rita Ventura; et al. "Biosynthesis of mycobacterial methylmannose polysaccharides requires a unique 1-O-methyltransferase specific for 3-O-methylated mannosides". Proceedings of the National Academy of Sciences 116 3 (2019): 835-844. https://doi.org/10.1073/pnas.1813450116. 10.1073/pnas.1813450116 Miranda, V.; Torcato, I.M.; Xavier, K.B.; Ventura, M.R.. "Synthesis of D-desthiobiotin-AI-2 as a novel chemical probe for autoinducer-2 quorum sensing receptors". Bioorganic Chemistry 92 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85071231268&partnerID=MN8TOARS. 10.1016/j.bioorg.2019.103200 Ramos, I.; Lourenço, E.C.; Ascenso, O.S.; Maycock, C.D.; Dasika, M.; Dickson, M.L.; Ventura, M.R.. "The effect of new compounds in stabilizing downstream monoclonal antibody (mAb) process intermediates". International Journal of Pharmaceutics 565 (2019): 162-173. http://www.scopus.com/inward/record.url?eid=2-s2.0-85065390591&partnerID=MN8TOARS. 10.1016/j.ijpharm.2019.04.080 Jessica G. M. Bevan; Eva C. Lourenço; Miguel Chaves-Ferreira; João A. Rodrigues; M. Rita Ventura. "Immobilization of UDP-Galactose on an Amphiphilic Resin". European Journal of Organic Chemistry (2018): https://doi.org/10.1002/ejoc.201701620. 10.1002/ejoc.201701620 Almeida, A.F.; Dos Santos, C.N.; Ventura, M.R.. "Polyphenols, their metabolites and derivatives as drug leads". Current Pharmaceutical Design 24 19 (2018): 2188-2207. http://www.scopus.com/inward/record.url?eid=2-s2.0-85054777574&partnerID=MN8TOARS. 10.2174/1381612824666180516103609 López de las Hazas, M.-C.; Godinho-Pereira, J.; Macià, A.; Almeida, A.F.; Ventura, M.R.; Motilva, M.-J.; Santos, C.N.. "Brain uptake of hydroxytyrosol and its main circulating metabolites: Protective potential in neuronal cells". Journal of Functional Foods 46 (2018): 110-117. http://www.scopus.com/inward/record.url?eid=2-s2.0-85046624284&partnerID=MN8TOARS. 10.1016/j.jff.2018.04.028 Ascenso, Osvaldo S; Torcato, Ines M; Miguel, Ana Sofia; Marques, Joao C; Xavier, Karina B; Ventura, M Rita; Maycock, Christopher D. "Synthesis and biological activity of a potent optically pure autoinducer-2 quorum sensing agonist.". Bioorganic chemistry 85 (2018): 75-81. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=MEDLINE&KeyUT=MEDLINE:30602129&KeyUID=MEDLINE:30602129. 10.1016/j.bioorg.2018.12.022 Saúl Silva; Osvaldo S. Ascenso; Eva C. Lourenço; Margarida Archer; Christopher D. Maycock; M. Rita Ventura. "Syntheses of the plant auxin conjugate 2-O-(indole-3-acetyl)-myo-inositol IAInos". Organic & Biomolecular Chemistry (2018): https://doi.org/10.1039/C8OB02096E. 10.1039/C8OB02096E Almeida, A.F.; Santos, C.N.; Ventura, M.R.. "Synthesis of New Sulfated and Glucuronated Metabolites of Dietary Phenolic Compounds Identified in Human Biological Samples". Journal of Agricultural and Food Chemistry 65 31 (2017): 6460-6466. http://www.scopus.com/inward/record.url?eid=2-s2.0-85027350812&partnerID=MN8TOARS. 10.1021/acs.jafc.6b05629 Ascenso, O.S.; Leitão, E.P.T.; Heggie, W.; Ventura, M.R.; Maycock, C.D.. "Monofluoroalkylation and alkylation of alcohols using non-volatile reagents". Tetrahedron 73 8 (2017): 1165-1169. http://www.scopus.com/inward/record.url?eid=2-s2.0-85009789190&partnerID=MN8TOARS. 10.1016/j.tet.2017.01.020 Figueira, I.; Garcia, G.; Pimpão, R.C.; Terrasso, A.P.; Costa, I.; Almeida, A.F.; Tavares, L.; et al. "Polyphenols journey through blood-brain barrier towards neuronal protection". Scientific Reports 7 1 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85029279509&partnerID=MN8TOARS. 10.1038/s41598-017-11512-6 Lourenço, E.C.; Ventura, M.R.. "Improvement of the stereoselectivity of the glycosylation reaction with 2-azido-2-deoxy-1-thioglucoside donors". Carbohydrate Research 426 (2016): 33-39. http://www.scopus.com/inward/record.url?eid=2-s2.0-84962425036&partnerID=MN8TOARS. 10.1016/j.carres.2016.03.021 Feliciano, R.P.; Boeres, A.; Massacessi, L.; Istas, G.; Ventura, M.R.; Nunes Dos Santos, C.; Heiss, C.; Rodriguez-Mateos, A.. "Identification and quantification of novel cranberry-derived plasma and urinary (poly)phenols". Archives of Biochemistry and Biophysics 599 (2016): 31-41. http://www.scopus.com/inward/record.url?eid=2-s2.0-84969640823&partnerID=MN8TOARS. 10.1016/j.abb.2016.01.014 Rodriguez-Mateos, A.; Feliciano, R.P.; Boeres, A.; Weber, T.; dos Santos, C.N.; Ventura, M.R.; Heiss, C.. "Cranberry (poly)phenol metabolites correlate with improvements in vascular function: A double-blind, randomized, controlled, dose-response, crossover study". Molecular Nutrition and Food Research 60 10 (2016): 2130-2140. http://www.scopus.com/inward/record.url?eid=2-s2.0-85027930724&partnerID=MN8TOARS. 10.1002/mnfr.201600250 Mendes, S.; Banha, C.; Madeira, J.; Santos, D.; Miranda, V.; Manzanera, M.; Ventura, M.R.; van Berkel, W.J.H.; Martins, L.O.. "Characterization of a bacterial pyranose 2-oxidase from Arthrobacter siccitolerans". Journal of Molecular Catalysis B: Enzymatic (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-85007560471&partnerID=MN8TOARS. 10.1016/j.molcatb.2016.11.005 Paixão, L.; Oliveira, J.; Veríssimo, A.; Vinga, S.; Lourenço, E.C.; Ventura, M.R.; Kjos, M.; et al. "Host glycan sugar-specific pathways in streptococcus pneumonia: Galactose as a key sugar in colonisation and infection". PLoS ONE 10 3 (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84926329287&partnerID=MN8TOARS. 10.1371/journal.pone.0121042 Vila-Real, H.; Ventura, M.R.; Maycock, C.; Iranzo, O.; Simplício, A.. "An Alternative Synthetic Route to (3 R,5 S,1' S)-5-{1'-[(tert -Butyloxycarbonyl)amino]-3'-methylbutyl}-3-methyldihydrofuran-2(3 H)-one, a Precursor of a Leu-Ala Hydroxyethylene Isostere". Synthesis (Germany) 47 19 (2015): 3009-3012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84941940175&partnerID=MN8TOARS. 10.1055/s-0034-1381036 Maranha, A.; Moynihan, P.J.; Miranda, V.; Correia Lourenço, E.; Nunes-Costa, D.; Fraga, J.S.; Jose Barbosa Pereira, P.; et al. "Octanoylation of early intermediates of mycobacterial methylglucose lipopolysaccharides". Scientific Reports 5 (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84940705326&partnerID=MN8TOARS. 10.1038/srep13610 Vila-Real, H.; Coelho, H.; Rocha, J.; Fernandes, A.; Ventura, M.R.; Maycock, C.D.; Iranzo, O.; Simplício, A.L.. "Peptidomimetic ß-Secretase Inhibitors Comprising a Sequence of Amyloid-ß Peptide for Alzheimer's Disease". Journal of Medicinal Chemistry 58 14 (2015): 5408-5418. http://www.scopus.com/inward/record.url?eid=2-s2.0-84937675445&partnerID=MN8TOARS. 10.1021/acs.jmedchem.5b00658 Lamosa, P.; Lourenço, E.C.; d’Avó, F.; Nobre, A.; Bandeiras, T.M.; da Costa, M.S.; Ventura, M.R.; Santos, H.. "A unique glyceryl diglycoside identified in the thermophilic, radiation-resistant bacterium Rubrobacter xylanophilus". Extremophiles 19 2 (2015): 373-382. http://www.scopus.com/inward/record.url?eid=2-s2.0-84925532850&partnerID=MN8TOARS. 10.1007/s00792-014-0723-0 Miranda, V.; Maycock, C.D.; Ventura, M.R.. "A Stereoselective Synthesis of (+)-Piscidic Acid and Cimicifugic Acid L". European Journal of Organic Chemistry 2015 34 (2015): 7529-7533. http://www.scopus.com/inward/record.url?eid=2-s2.0-84955178869&partnerID=MN8TOARS. 10.1002/ejoc.201501002 Pimpão, R.C.; Ventura, M.R.; Ferreira, R.B.; Williamson, G.; Santos, C.N.. "Phenolic sulfates as new and highly abundant metabolites in human plasma after ingestion of a mixed berry fruit purée". British Journal of Nutrition 113 3 (2015): 454-463. http://www.scopus.com/inward/record.url?eid=2-s2.0-84922676982&partnerID=MN8TOARS. 10.1017/S0007114514003511 Paixão, L.; Oliveira, J.; Veríssimo, A.; Vinga, S.; Lourenço, E.C.; Ventura, M.R.. "Correction: Host glycan sugar-specific pathways in Streptococcus pneumonia: Galactose as a key sugar in colonisation and infection". PLoS ONE 10 4 (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84929471870&partnerID=MN8TOARS. 10.1371/journal.pone.0127483 Marques, J.C.; Oh, I.K.; Ly, D.C.; Lamosa, P.; Ventura, M.R.; Miller, S.T.; Xavier, K.B.. "LsrF, a coenzyme A-dependent thiolase, catalyzes the terminal step in processing the quorum sensing signal autoinducer-2". Proceedings of the National Academy of Sciences of the United States of America 111 39 (2014): 14235-14240. http://www.scopus.com/inward/record.url?eid=2-s2.0-84907587733&partnerID=MN8TOARS. 10.1073/pnas.1408691111 Ventura, M.R.; Lima, Maria. "Asymmetric syntheses based on organocatalysis". Mini-Reviews in Organic Chemistry 11 2 (2014): 154-163. http://www.scopus.com/inward/record.url?eid=2-s2.0-84905568407&partnerID=MN8TOARS. 10.2174/1570193X1102140609120227 Maycock, C.D.; Rodrigues, P.; Ventura, M.R.. "Use of aziridines for the stereocontrolled synthesis of (-)-LL-C10037a, (+)-MT35214, and (+)-4-epi-MT35214". Journal of Organic Chemistry 79 5 (2014): 1929-1937. http://www.scopus.com/inward/record.url?eid=2-s2.0-84896800953&partnerID=MN8TOARS. 10.1021/jo402535j Alarico, S.; Costa, M.; Sousa, M.S.; Maranha, A.; Lourenço, E.C.; Faria, T.Q.; Ventura, M.R.; Empadinhas, N.. "Mycobacterium hassiacum recovers from nitrogen starvation with up-regulation of a novel glucosylglycerate hydrolase and depletion of the accumulated glucosylglycerate". Scientific Reports 4 (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84925854243&partnerID=MN8TOARS. 10.1038/srep06766 Lamosa, P.; Rodrigues, M.V.; Gonçalves, L.G.; Carr, J.; Ventura, R.; Maycock, C.; Raven, N.D.; Santos, H.. "Organic solutes in the deepest phylogenetic branches of the Bacteria: Identification of a(1-6)glucosyl-a(1-2)glucosylglycerate in Persephonella marina". Extremophiles 17 1 (2013): 137-146. http://www.scopus.com/inward/record.url?eid=2-s2.0-84871462775&partnerID=MN8TOARS. 10.1007/s00792-012-0500-x Nobre, A.; Empadinhas, N.; Nobre, M.F.; Lourenço, E.C.; Maycock, C.; Ventura, M.R.; Mingote, A.; da Costa, M.S.. "The plant Selaginella moellendorffii possesses enzymes for synthesis and hydrolysis of the compatible solutes mannosylglycerate and glucosylglycerate". Planta 237 3 (2013): 891-901. http://www.scopus.com/inward/record.url?eid=2-s2.0-84874320704&partnerID=MN8TOARS. 10.1007/s00425-012-1808-6 Lourenço, E.C.; Ventura, M.R.. "The effect of electron withdrawing protecting groups at positions 4 and 6 on 1,2-cis galactosylation". Tetrahedron 69 34 (2013): 7090-7097. http://www.scopus.com/inward/record.url?eid=2-s2.0-84880131953&partnerID=MN8TOARS. 10.1016/j.tet.2013.06.038 Rui, F.; Marques, J.C.; Miller, S.T.; Maycock, C.D.; Xavier, K.B.; Ventura, M.R.. "Stereochemical diversity of AI-2 analogs modulates quorum sensing in Vibrio harveyi and Escherichia coli". Bioorganic and Medicinal Chemistry 20 1 (2012): 249-256. http://www.scopus.com/inward/record.url?eid=2-s2.0-84855192035&partnerID=MN8TOARS. 10.1016/j.bmc.2011.11.007 Maycock, C.D.; Rita Ventura, M.. "New organocatalysts derived from tartaric and glyceric acids for direct aldol reactions". Tetrahedron Asymmetry 23 17 (2012): 1262-1271. http://www.scopus.com/inward/record.url?eid=2-s2.0-84867034435&partnerID=MN8TOARS. 10.1016/j.tetasy.2012.08.008 Lourenço, Eva C.; Ventura, M. Rita. "Synthesis of Potassium (2R)-2-O-a-D-Mannopyranosyl-(1¿2)-a-D-glucopyranosyl-2,3-dihydroxypropanoate: A Naturally Compatible Solute". European Journal of Organic Chemistry 2011 33 (2011): 6698-6703. http://dx.doi.org/10.1002/ejoc.201100934. 10.1002/ejoc.201100934 João C. Marques; Pedro Lamosa; Caitlin Russell; Rita Ventura; Christopher Maycock; Martin F. Semmelhack; Stephen T. Miller; Karina B. Xavier. "Processing the Interspecies Quorum-sensing Signal Autoinducer-2 (AI-2)". Journal of Biological Chemistry 286 20 (2011): 18331-18343. https://doi.org/10.1074%2Fjbc.m111.230227. 10.1074/jbc.m111.230227 Ascenso, O.S.; Marques, J.C.; Santos, A.R.; Xavier, K.B.; Rita Ventura, M.; Maycock, C.D.. "An efficient synthesis of the precursor of AI-2, the signalling molecule for inter-species quorum sensing". Bioorganic and Medicinal Chemistry 19 3 (2011): 1236-1241. http://www.scopus.com/inward/record.url?eid=2-s2.0-79551471667&partnerID=MN8TOARS. 10.1016/j.bmc.2010.12.036 Marques, J.C.; Lamosa, P.; Russell, C.; Ventura, R.; Maycock, C.; Semmelhack, M.F.; Miller, S.T.; Xavier, K.B.. "Processing the interspecies quorum-sensing signal autoinducer-2 (AI-2): Characterization of phospho-(S)-4,5-dihydroxy-2,3-pentanedione isomerization by LsrG protein". Journal of Biological Chemistry 286 20 (2011): 18331-18343. http://www.scopus.com/inward/record.url?eid=2-s2.0-79955945955&partnerID=MN8TOARS. 10.1074/jbc.M111.230227 Jorge, C.D.; Ventura, R.; Maycock, C.; Outeiro, T.F.; Santos, H.; Costa, J.. "Assessment of the efficacy of solutes from extremophiles on protein aggregation in cell models of Huntington's and Parkinson's diseases". Neurochemical Research 36 6 (2011): 1005-1011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79955681334&partnerID=MN8TOARS. 10.1007/s11064-011-0440-3 Loureno, E.C.; Ventura, M.R.. "The synthesis of compatible solute analogues-solvent effects on selective glycosylation". Carbohydrate Research 346 2 (2011): 163-168. http://www.scopus.com/inward/record.url?eid=2-s2.0-78651367543&partnerID=MN8TOARS. 10.1016/j.carres.2010.08.007 Lourenço, Eva C.; Maycock, Christopher D.; Rita Ventura, M.. "Synthesis of potassium (2R)-2-O-a-d-glucopyranosyl-(1¿6)-a-d-glucopyranosyl-2,3-dihydroxypropanoate a natural compatible solute". Carbohydrate Research 344 15 (2009): 2073-2078. http://dx.doi.org/10.1016/j.carres.2009.06.037. Published • 10.1016/j.carres.2009.06.037 Faria, T.Q.; Mingote, A.; Siopa, F.; Ventura, R.; Maycock, C.; Santos, H.. "Design of new enzyme stabilizers inspired by glycosides of hyperthermophilic microorganisms". Carbohydrate Research 343 18 (2008): 3025-3033. http://www.scopus.com/inward/record.url?eid=2-s2.0-55049115053&partnerID=MN8TOARS. 10.1016/j.carres.2008.08.030 Rodrigues, M.V.; Borges, N.; Henriques, M.; Lamosa, P.; Ventura, R.; Fernandes, C.; Empadinhas, N.; et al. "Bifunctional CTP:inositol-1-phosphate cytidylyltransferase/CDP-inositol: Inositol-1-phosphate transferase, the key enzyme for di-myo-inositol-phosphate synthesis in several (hyper)thermophiles". Journal of Bacteriology 189 15 (2007): 5405-5412. http://www.scopus.com/inward/record.url?eid=2-s2.0-34547629796&partnerID=MN8TOARS. 10.1128/JB.00465-07 Burke, A.J.; Maycock, C.D.; Ventura, M.R.. "Stereoselective alkylation of tartrate derivatives. A concise route to (+)-O-methylpiscidic acid and natural analogues". Organic and Biomolecular Chemistry 4 12 (2006): 2361-2363. http://www.scopus.com/inward/record.url?eid=2-s2.0-33745110607&partnerID=MN8TOARS. 10.1039/b606362b Borges, N.; Gonçalves, L.G.; Rodrigues, M.V.; Siopa, F.; Ventura, R.; Maycock, C.; Lamosa, P.; Santos, H.. "Biosynthetic pathways of inositol and glycerol phosphodiesters used by the hyperthermophile Archaeoglobus fulgidus in stress adaptation". Journal of Bacteriology 188 23 (2006): 8128-8135. http://www.scopus.com/inward/record.url?eid=2-s2.0-33751559039&partnerID=MN8TOARS. 10.1128/JB.01129-06 Ramos, A.; Neves, A.R.; Ventura, R.; Maycock, C.; López, P.; Santos, H.. "Effect of pyruvate kinase overproduction on glucose metabolism of Lactococcus lactis". Microbiology 150 4 (2004): 1103-1111. http://www.scopus.com/inward/record.url?eid=2-s2.0-1942440947&partnerID=MN8TOARS. Noronha, M.; Lima, J.C.; Lamosa, P.; Santos, H.; Maycock, C.; Ventura, R.; Maçanita, A.L.. "Intramolecular Fluorescence Quenching of Tyrosine by the Peptide a-Carbonyl Group Revisited". Journal of Physical Chemistry A 108 12 (2004): 2155-2166. http://www.scopus.com/inward/record.url?eid=2-s2.0-1842788226&partnerID=MN8TOARS. 10.1021/jp037125l Barros, M.T.; Maycock, C.D.; Ventura, M.R.. "Aldol Reactions of Dioxanes Derived from Tartaric Acid. A Total Synthesis of (+)-Nephrosteranic Acid". Organic Letters 5 22 (2003): 4097-4099. http://www.scopus.com/inward/record.url?eid=2-s2.0-0344514156&partnerID=MN8TOARS. 10.1021/ol0354932 Barros, M.T.; Matias, P.M.; Maycock, C.D.; Ventura, M.R.. "Aziridines as a Protecting and Directing Group. Stereoselective Synthesis of (+)-Bromoxone". Organic Letters 5 23 (2003): 4321-4323. http://www.scopus.com/inward/record.url?eid=2-s2.0-0345359348&partnerID=MN8TOARS. 10.1021/ol035576i Lamosa, P.; Turner, D.L.; Ventura, R.; Maycock, C.; Santos, H.. "Protein stabilization by compatible solutes: Effect of diglycerol phosphate on the dynamics of Desulfovibrio gigas rubredoxin studied by NMR". European Journal of Biochemistry 270 23 (2003): 4606-4614. http://www.scopus.com/inward/record.url?eid=2-s2.0-0344393574&partnerID=MN8TOARS. 10.1046/j.1432-1033.2003.03861.x Barros, M.T.; Maycock, C.D.; Ventura, M.R.. "A synthesis of aziridines from a-iodoenones". Tetrahedron Letters 43 24 (2002): 4329-4331. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037053871&partnerID=MN8TOARS. 10.1016/S0040-4039(02)00791-8 Barros, M.T.; Maycock, C.D.; Ventura, M.R.. "Stereoselective Radical Reactions of Some Tartaric and Glyceric Acid Derivatives". Organic Letters 4 12 (2002): 2035-2038. http://www.scopus.com/inward/record.url?eid=2-s2.0-0042891588&partnerID=MN8TOARS. 10.1021/ol025880w Neves, A.R.; Ventura, R.; Mansour, N.; Shearman, C.; Gasson, M.J.; Maycock, C.; Ramos, A.; Santos, H.. "Is the glycolytic flux in Lactococcus lactis primarily controlled by the redox charge? Kinetics of NAD⁺ and NADH pools determined in vivo by ¹³C NMR". Journal of Biological Chemistry 277 31 (2002): 28088-28098. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037008786&partnerID=MN8TOARS. 10.1074/jbc.M202573200 Barros, M.T.; Maycock, C.D.; Ventura, M.R.. "Approaches to the synthesis of (+)- and (-)-epibatidine". Journal of the Chemical Society. Perkin Transactions 1 2 (2001): 166-173. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035925012&partnerID=MN8TOARS. Barros, M.T.; Maycock, C.D.; Madureira, M.I.; Ventura, M.R.. "The effect of diethylamine on Stille alkylations with tetraalkylstannanes". Chemical Communications 17 (2001): 1662-1663. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035823306&partnerID=MN8TOARS. Barros, M.T.; Maycock, C.D.; Ventura, M.R.. "The First Synthesis of (-)-Asperpentyn and Efficient Syntheses of (+)-Harveynone, (+)-Epiepoformin and (-)-Theobroxide". Chemistry - A European Journal 6 21 (2000): 3991-3996. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034602117&partnerID=MN8TOARS. 10.1002/1521-3765(20001103)6:21<3991::AID-CHEM3991>3.3.CO;2-M Barros, M.T.; Maycock, C.D.; Ventura, M.R.. "The effect of DMSO on the borohydride reduction of a cyclohexanone: A formal enantioselective synthesis of (+)-epibatidine". Tetrahedron Letters 40 3 (1999): 557-560. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033556073&partnerID=MN8TOARS. 10.1016/S0040-4039(98)02354-5 Barros, M.T.; Maycock, C.D.; Ventura, M.R.. "The enantioselective total synthesis of epoformin and analogues". Tetrahedron 55 11 (1999): 3233-3244. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033105328&partnerID=MN8TOARS. 10.1016/S0040-4020(98)01136-3 Alves, C.; Barros, M.T.; Maycock, C.D.; Ventura, M.R.. "An efficient transformation of quinic acid to shikimic acid derivatives". Tetrahedron 55 28 (1999): 8443-8456. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033538623&partnerID=MN8TOARS. 10.1016/S0040-4020(99)00431-7 Barros, M.T.; Maycock, C.D.; Ventura, M.R.. "Enantioselective total synthesis of (+)-eutypoxide B". Journal of Organic Chemistry 62 12 (1997): 3984-3988. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030851937&partnerID=MN8TOARS. 10.1021/jo9617326
Newsletter article	Rebelo, Bárbara A.; M. Rita Ventura; Abranches, Rita. "CAROTENOIDS IN OUR DAILY LIFE", EUROCAROTEN, 2020, https://www.eurocaroten.eu/node/54.
Preprint	Rafael Carecho; Daniela Marques; Diogo Carregosa; Domenico Masuero; Mar Garcia-Aloy; Federica Tramer; Sabina Passamonti; et al. "Circulating (poly)phenol metabolites in the brain: unveiling in vitro and in vivo blood-brain barrier transport". 2024. https://doi.org/10.1101/2024.02.27.582339. 10.1101/2024.02.27.582339 Taborda, André; Frazão, Tomas; Rodrigues, Miguel V.; Fernández-Luengo, Xavier; Sancho, Ferran; Lucas, Maria Fátima; Frazão, Carlos; et al. "Mechanistic Insights into Glycoside 3-Oxidases Involved in C-Glycoside Metabolism in Soil Microorganisms". 2023. http://dx.doi.org/10.21203/rs.3.rs-2662172/v1. 10.21203/rs.3.rs-2662172/v1 Ana Maranha; Mafalda Costa; Jorge Ripoll-Rozada; Jose Manso; Vanessa Miranda; Vera Mendes; Bruno Manadas; et al. "Self-recycling and partially conservative replication of mycobacterial methylmannose polysaccharides". 2022. https://doi.org/10.21203/rs.3.rs-1362692/v1. 10.21203/rs.3.rs-1362692/v1
Thesis / Dissertation	M. Rita Ventura. "The Asymmetric Syntheses of Natural Compounds Starting From (-)-Quinic Acid". PhD, Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, 1999.

Intellectual property

Patent

Lima, Maria. 2014. "Hexose derivatives, preparation and uses thereof".
Lima, Maria. 2012. "Method for the preparation of biologically active compounds".
Lima, Maria. 2007. "Utilization of compatible solutes to improve the performance of the techniques using immobilized biologic materials".
Lima, Maria. 2007. "Synthetic mannosylglycerate derivatives for the stabilisation and preservation of biomaterials".
Lima, Maria. 2006. "Derivados sintéticos de manosil-glicerato para a estabilização e/ou preservação de biomateriais.".

Provisional application for patent

2024. "Process for producing ketocarotenoids by modified plant cell cultures and products thereof. R. Abranches, M. R. Ventura, B. A. Rebelo. PT119276, 26 February 2024.".

Other

Spin-off company

2013. Extremochem. Synthesis of new protein stabilisers.

Activities

Oral presentation

	Presentation title	Event name Host (Event location)
2024/01/24	A novel functional assay for the discovery of new drug targets in mycobacteria. Invited Keynote Lecture.	15th National Organic Chemistry Meeting and 8th National Medicinal Chemistry Meeting (Faro, Portugal)
2023/10/17	Carbohydrate synthesis for solving biological problems	Chemical Horizons Lectures of the Slovak Chemical Society. Institute of Chemistry, SAS, Bratislava, Slovakia (Bratislava, Slovakia)
2023/01/17	Synthesis of (oligo)arabinosides and development of a functional assay for the study of enzymes involved in mycobacteria cell wall biosynthesis. M. Rita Ventura. Invited Lecture.	14th International Meeting of the Portuguese Carbohydrate Group – GLUPOR 14 (Caparica, Portugal)
2021/09/02	Exploring thioureas versatility as organocatalysts. Rénio, M.; Murtinho, D.; Ventura, M. R.	IsySyCat 2021 (Évora, Portugal)
2021/01/11	Carbohydrate synthesis for solving biological problems. Ventura, M. R.	Cost Action CA18132 – GlycoNanoProbes. WC1 Meeting Cost Action CA18132
2019/10/24	Carbohydrate synthesis for solving biological problems. Ventura, M. R.	1st Annual Symposium Cost Action CA18103 – Innovation with glycans: New Frontiers from synthesis to new biological targets (Santiago de Compostela, Spain)
2018/07/14	Carbohydrate synthesis for solving biological problems - Invited Lecture. Ventura, M. R.; Rénio, M.; Bevan, J.; Lourenço, E. C.; Rodrigues, J. A.	ICS2018 – 29th International Carbohydrate Symposium (Lisboa, Portugal)
2015/06	Study and Modulation of Inter-species Quorum Sensing by AI-2 Analogues. Ventura, M. R.; Ascenso, O. S.; Rui, F.; Miguel, A. S.; Marques, J. C.; Xavier, K. B.	I International Symposium on Quorum Sensing Inhibition (Santiago de Compostela, Spain)
2013/09	Study and modulation of inter-species quorum sensing by AI-2 analogues - Invited Lecture Ventura, M. R.; Ascenso, O. A.; Miguel, A. S.; Rui, F.; Marques, J. C.; Maycock, C. D.; Xavier, K. B.	10º Encontro Nacional de Química Orgânica (Lisboa, Portugal)
2012/11	Organocatalysts Derived from Tartaric and Glyceric Acids. Ventura, M. R.	3rd COST ORCA Meeting (Athens, Greece)
2009/09	Synthesis of sugars with protein stabilising properties isolated from extremophiles - Invited Lecture. Ventura, M. R.; Lourenço, E. C.	8th International Meeting of the Portuguese Carbohydrate Group (Braga, Portugal)
1999/07	Preparation and Reactions of Enones Derived from Quinic Acid. Ventura, M. R.; Barros, M. T.; Maycock, C. D.	3º Encontro Nacional de Química Orgânica (Covilhã, Portugal)

Supervision

	Thesis Title Role	Degree Subject (Type) Institution / Organization
2024/11/01 - Current	Multidisciplinary approach to enhance nose-to-brain biologics delivery using nanoparticles: synthesis, formulation and evaluation Supervisor of Inês Afonso	Biociências Moleculares (PhD) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2024/11/01 - Current	Development of conformationally defined glyco-foldamer microarrays as sensitive screening platforms for glycan-based diagnosis and therapeutic strategies in cancer Supervisor of Márcia Saraiva	Biociências Moleculares (PhD) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica António Xavier, Portugal
2024/06/01 - Current	New Carbohydrate Oxidising Enzymes prepared by directed evolution and their application in synthesis of AminoGlycoside derivatives with antibiotic potential and rare sugars. Supervisor of Elena Potocká	101152159 — COxEnzymes - AGs. HORIZON-MSCA-2023-PF-01-01 — MSCA Postdoctoral Fellowships 2023 (Other) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2023/10/01 - Current	New Approaches Towards Parkinson Disease treatment: targeting TRPLM1 channel. Supervisor of Miguel Mira	Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica António Xavier, Portugal
2023 - Current	Development of new (poly)phenol analogues and chemical probes for neuroprotection Supervisor of Inês Paiva	Química Sustentável (PhD) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2022/11/01 - Current	Biocatalytic synthesis of oligoarabinosides for the study of drug targets and development of novel anti-tuberculosis drugs Supervisor of Miguel Mira	Postgraduate Program on Research Practice Level 1. (Scientific initiation) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2022/06/01 - Current	Development of new AI-2 prodrugs and chemical probes to study the microbiota of the mammalian gastro-intestinal tract. Supervisor of Peter Kis	Post doctoral ERA fellowship 101067572: AI-2 Prodrugs. Seal of excellence awarded (Other) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2021/01/01 - Current	Structure-based design and synthesis of novel potential anti-tuberculosis drugs Supervisor of Cristiano Conceição	Química Sustentável (PhD) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2020/10 - Current	Microbiota derived metabolites from dietary phenolics and their potential to mitigate neuroinflammation Co-supervisor of Diogo Carregosa	Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas, Portugal
2019/10/01 - Current	Evaluation of the therapeutic properties of oleocanthal, oleacein and analogues Supervisor of Beatriz Martins	Química Sustentável (PhD) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2019/01/01 - Current	Metabolic engineering of carotenoids in algae and angiosperms: searching for an alternative production system Co-supervisor of Bárbara Almeida Rebelo	Biologia de Plantas - Plantas para a Vida (PhD) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2017/01/01 - Current	New opportunities to explore Cyclophilin D as a drug target Co-supervisor of Diana Silva	Biociências Moleculares (PhD) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal Instituto de Biologia Experimental e Tecnológica, Portugal
2016/02/01 - Current	Design and applications of novel organocatalysts Supervisor of João Cascão	Química Sustentável (PhD) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2023/09 - 2024/01	Erasmus exchange student from the HU University of Applied Sciences Utrecht, Institute for Life Sciences and Chemistry, Netherlands. Supervisor of Amir Shokir	Erasmus student (Other)
2018/02/01 - 2023/07/18	Development of new catalysts for asymmetric reactions and their application in the total synthesis of biologically active compounds Supervisor of Márcia Rénio	Química Sustentável (PhD) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2021/09/01 - 2022/12/12	Synthesis of new recyclable organocatalysts for stereoselective synthesis. Supervisor of Daniela Marques	Engenharia Química e Biológica (Master) Instituto Politécnico de Lisboa Instituto Superior de Engenharia de Lisboa, Portugal
2021/07/01 - 2022/07/26	Design and Synthesis of New Autoinducer-2 Chemical Probes. Supervisor of Miguel Rodrigues	Postgraduate Program on Research Practice Level 1. (Scientific initiation) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2022/01 - 2022/06/30	Synthesis of intermediates for protein kinase C agonists total synthesis Supervisor of Nuno Miguel Saraiva	Bioquímica (Degree) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2021/10/01 - 2022/05/31	Deciphering the mechanisms of interspecies bacterial communication towards the manipulation of the mammalian gut microbiota Supervisor of Peter Kis	PhD Holder contract (Other) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2020/09/01 - 2022/02/24	Synthesis and evaluation of phenolic metabolites and analogues Supervisor of Diogo Mendes	Mestrado em Química Bioorgânica (Master) Universidade Nova de Lisboa Departamento de Química, Portugal
2019/09 - 2021/07/31	Deciphering the mechanisms of interspecies bacterial communication towards the manipulation of the mammalian gut microbiota (AI-2 Probes) Supervisor of Gonzalo Carrau	PhD holder contract (Other) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2020/01/01 - 2021/06/17	Design and synthesis of novel anti-tuberculosis drugs based on the discovery of membrane proteins involved in mycobacteria cell wall biosynthesis. Supervisor of Cristiano ConceiçãoI	Postgraduate Program on Research Practice Level 1 (Scientific initiation) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2019/11 - 2020/07	Deciphering the mechanisms of interspecies bacterial communication towards the manipulation of the mammalian gut microbiota Supervisor of Vanessa Miranda	PhD Holder contract (Other) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2015/02/01 - 2019/10/08	Synthesis of new bioactive autoinducer-2 analogues Supervisor of Vanessa Miranda	Chemistry (PhD) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2019/01/21 - 2019/06/21	Development of one-pot glycosylation methods Supervisor of Elodie Hardine	Erasmus student (Other) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2017/09/01 - 2018/10/25	Development of a one-pot glycosylation method for the synthesis of MMP precursors Supervisor of Miguel Bernardo	Química Bioorgânica (Master) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2017/09/01 - 2018/10/19	Design, synthesis and biological evaluation of new derivatives of phenolic metabolites Supervisor of Diogo Carregosa	Bioquímica para a Saúde (Master) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2018/03 - 2018/07	Improved synthesis of AI-2 Supervisor of Georgia Lazana	Erasmus Student (Other) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2015 - 2018/04/27	Chemical tools for the study of N- glycosylation in protozoan parasites Co-supervisor of Jessica Bevan	Associação para a Investigação e Desenvolvimento da Faculdade de Medicina, Portugal Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2016/09/01 - 2017/11/08	Chemical synthesis of new histone deacetylase inhibitors and their evaluation as inducers of recombinant protein production in plants Supervisor of Bárbara Almeida Rebelo	Bioquímica para a Saúde (Master) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2016/01/01 - 2017/04/30	RNA mimics of GFP for single cell analysis of gene expression in the intestinal pathogen Clostridium difficile: synthesis and validation of new red-shifted fluorophores Supervisor of Naiara Fernandez	Postdoctoral researcher (Other) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2015/09/01 - 2016/11/30	Chemical Synthesis of new histone deacetylase inhibitors and their evaluation as anticancer agents Supervisor of Diana Silva	Bioquímica para a Saúde (Master) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2015 - 2016	New organocatalysts for light activated asymmetric catalysis Supervisor of João Cascão	Prize Awardee (Other) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal Fundação Calouste Gulbenkian, Portugal
2015 - 2016	Síntese de um organocatalisador derivado do ácido tartárico e aplicação em reações aldol enantioseletivas diretas Supervisor of Miguel Bernardo	Bioquímica (Degree) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2014/09/01 - 2015/10/26	Synthesis of precursors of the rare 3-O-methylmannose polysaccharides present in Nontuberculous Mycobacteria Supervisor of André Sequeira	Química Bioorgânica (Master) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2013/01/01 - 2014/03/24	Desenvolvimento de uma síntese eficiente do precursor do AI-2 e análogos Supervisor of Osvaldo Ascenso	Química Bioorgânica (Master) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2013 - 2014	Modulação epigenética da expressão de transgenes através de compostos químicos potenciadores Supervisor of Carina Figueiredo	Bioquímica (Degree) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2012/10/01 - 2013/12/31	Studies on the structure/activity relationship of AI-2, a bacterial signalling molecule for interspecies communication Supervisor of Ana Sofia Miguel	Postdoctoral Researcher (Other) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2008 - 2013/12/20	Synthesis of New Enzyme Stabilisers Inspired by Compatible Solutes of Hyperthermophilic Microorganisms Supervisor of Eva Lourenço	Biotechnology (PhD) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2012 - 2013	Produção de proteínas recombinantes em culturas de células vegetais: modulação epigenética da expressão de transgenes através de compostos químicos potenciadores Supervisor of Lara Fidalgo	Bioquímica (Degree) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2012/06/04 - 2012/08/18	Leonardo da Vinci exchange student Supervisor of Adrián Prol Nogueira	Leonardo da Vinci exchange student (Other) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2011 - 2012	Síntese de Análogo do AI-2, molécula sinalizadora de quorum sensing Supervisor of João Cascão	Bioquímica (Degree) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2009 - 2011	Modified Bacterial Signals Supervisor of Fábio Rui	Postdoctoral Researcher (Other) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal Instituto Gulbenkian de Ciência, Portugal
2010/05/09 - 2010/07/17	Leonardo da Vinci exchange student Supervisor of Roberto Cianci	Leonardo da Vinci exchange student (Other) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2006/09/01 - 2008/10/06	Estudos para a síntese em suporte sólido de uma biblioteca de compostos Supervisor of Eva Lourenço	Química Verde (Master) Universidade de Lisboa Faculdade de Ciências, Portugal
2008/01/15 - 2008/03/20	Leonardo da Vinci exhange student Supervisor of Matia Curci	Leonardo da Vinci exhange student (Other) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal

Event organisation

	Event name Type of event (Role)	Institution / Organization
2005 - Current	Organisation and participation in Dia Aberto, ITQB NOVA. (2005) Other (Member of the Organising Committee)	Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2007/09/12 - 2007/09/15	Member of the organising and scientific committees Glupor 7 - 7th International Meeting of the Portuguese Carbohydrate Group (2007/09/12 - 2007/09/15) Conference (Member of the Organising Committee)	Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal Sociedade Portuguesa de Química, Portugal
1997 - 1997	Member of the local organising committee for the 2º Encontro Nacional de Química Orgânica, Oeiras, Portugal (1997/09/17 - 1997/09/19) Conference	Sociedade Portuguesa de Química, Portugal Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal

Event participation

	Activity description Type of event	Event name Institution / Organization
2022 - 2022	First Aid Training - Certificado de Formação Profissional de Primeiros Socorros, Escola Nacional de Bombeiros. Workshop	Escola Nacional de Bombeiros, Portugal
2020/06/17 - 2020/11/09	EIT FOOD Government Executive Academy at the University of Warsaw, Poland Workshop	EIT FOOD Government Executive Academy
2019 - 2019	First Aid Training - Certificado de Formação Profissional de Primeiros Socorros, Escola Nacional de Bombeiros. Workshop	Escola Nacional de Bombeiros, Portugal
2011 - 2011	Attendance of the Cohitec Program 2011, which led to the creation of the startup Extremochem. Workshop	Cohitec Program COTEC Portugal, Portugal
2004 - 2004	Curso Aptidão Pedagógica de Formadores (CAP) Workshop	Curso Aptidão Pedagógica de Formadores
1990 - 1995	Diplôme Pratique de la Langue Française from Alliance Française de Lisbonne.
1988 - 1988	English as a Foreign Language Certificate from the American Language Institute of Lisbon. Other

Jury of academic degree

	Topic Role	Candidate name (Type of degree) Institution / Organization
2023/07/19	Member of the PhD juri of Diogo Silva, A closer look at a potential biocatalyst: Unravelling the catalytic, stability and structural features of PpDyP, a DyP-type Peroxidase. (Thesis) Arguer	Diogo Silva (PhD) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica António Xavier, Portugal
2022/07/22	Síntese de ligandos e catalisadores quirais para transformações assimétricas. (Thesis) Main arguer	Nélia Tavares (PhD) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2022/06/15	Member of the Examining Committee for final thesis dissertation of the Ph.D Course of Human Health and Biomedical Sciences, XXXIV cycle, PhD, Facoltà di Medicina e Chirurgia Università Politecnica delle Marche, Via Tronto, Ancona, Italy. (Thesis) Main arguer	Alessia Salvuci (PhD)
2021/12/21	Development of hybrid molecules of anti-tumour triazenes that target iron metabolism (Thesis) Main arguer	André Pires (Master) Universidade de Lisboa Faculdade de Farmácia, Portugal
2020/07/17	Novel Stereoselective Transformations under Lewis Base catalysis (Thesis) Main arguer	Lorena García Maestre (PhD) Universidad del País Vasco, Spain
2019/12/20	Desenvolvimento de fármacos híbridos antitumorais direccionados para o lisossoma (Thesis) Main arguer	Andreia Figueiredo (Master) Universidade de Lisboa Faculdade de Farmácia, Portugal
2019/05/13	Síntese de novas macromoléculas funcionalizadas para eventual aplicação no transporte de fármacos (Thesis) Main arguer	Cristiano Conceição (Master) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2019	Organocatalytic and Enantioselective Transannular Reactions: Novel Strategies for the Asymmetric Synthesis of Polycyclic Structures Thesis Member	Raquel Mato Santamaría, (PhD) Universidad del País Vasco, Spain
2018/01/10	SÍNTESE DE PRODUTOS NATURAIS USANDO O ÁCIDO TARTÁRICO COMO MATERIAL DE PARTIDA (Thesis) Main arguer	Ana Margarida Condinho (Master) Universidade de Lisboa Faculdade de Ciências, Portugal
2017/10/14	Rethinking Triazoles as Antifungals: Synthesis and Evaluation of New Triazole Derivatives (Thesis) Main arguer	Andreia Vieira (Master) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2017	Covalent activation of versatile compounds in organocatalyzed reactions towards the development of new methodologies Thesis Member	Eduardo Sánchez Díez (PhD) Universidad del País Vasco, Spain
2016/07/20	MICHAEL INITIATED ORGANOCATALYTIC CASCADE REACTIONS (Thesis) Main arguer	Iker Riaño Castela (PhD) Universidad del País Vasco, Spain
2016/04/29	Synthetic approach towards biomass derived pyridinium salts (Thesis) Arguer	Sowmiah Subbiah (PhD) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2015/10/26	A molecular view of dental restoration (Thesis) Main arguer	Helena Laronha (Master) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2015/04/20	Synthesis of Polymeric Nanoparticles for biomedical delivery applications (Thesis) Arguer	Carina Isabel Correia Crucho (PhD) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2014/10/28	New synthetic methodologies from biorenewable resources (Thesis) Arguer	Svilen Plamenov Simeonov (PhD) Universidade de Lisboa Faculdade de Farmácia, Portugal
2014/02/28	Synthesis of Iminosugars Through Diastereo/Enantioselective Diels-Alder Cycloaddition (Thesis) Main arguer	Vera Cristiana Moreira Duarte (PhD) Universidade do Minho Escola de Ciências, Portugal
2014	6-Hydroxy-2H-pyran-3(6H)-one Derivatives as Versatile Reagents in Organocatalytic and Enantioselective Reactions Thesis Member	Ane Orue Dañobeitia (PhD) Universidad del País Vasco, Spain
2013/07/16	Péptidos para a detecção de agregados de alfa-sinucleína (Thesis) Main arguer	Letícia Quental (Master) Universidade de Lisboa Faculdade de Farmácia, Portugal
2008/11/28	Síntese de peptidoglicano bacteriano reconhecido pelo sistema imunitário (Thesis) Main arguer	Luísa Carvalho (Master) Universidade de Lisboa Instituto Superior Técnico, Portugal
2007/07/27	Asymmetric Synthesis Using Chiral Pool Hydroxyacids Thesis Member	Jorge Bruno Reis Wahnon (PhD) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2006/04/10	Síntese de benzo : estudos de fluorescência, fotocromismo e actividade biológica : [b]tienilaminoácidos e ciclização intramolecular C-N a sistemas heteroaromáticos bi ou tricíclicos (Thesis) Main arguer	Ana Sofia Lemos Machado Abreu (PhD) Universidade do Minho Escola de Ciências, Portugal

Committee member

	Activity description Role	Institution / Organization
2023/10 - Current	Management Committee Member of COST Action CA22109: Medicinal plants for animal health care: Translating tradition into modern veterinary medicine (MedPlants4Vet). Member	European Cooperation in Science and Technology, Belgium
2023 - Current	Substitute Member of the Scientific Council of ITQB NOVA.	Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica António Xavier, Portugal
2023 - Current	Member of the Safety and Floor Coordination Commitee of ITQB. Chemistry Building Coordinator for ITQB NOVA. Member	Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica António Xavier, Portugal
2006 - Current	Member of the ITQB Infra-Structure Support Committee since 2006 Member	Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2016 - 2022	Member of the Scientific Council of ITQB NOVA since September 2016 Member	Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2005 - 2022	Member (Deputy) of the Safety and Floor Coordination Commitee of ITQB. Member	Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2019 - 2021	Management Committee Substitute Member of COST Action CA18103 Innovation with Glycans: new frontiers from synthesis to new biological targets Member	European Cooperation in Science and Technology, Belgium
2017 - 2021	Member of the organising committee and host of The Frontier Leaders of Today for the Scientists of Tomorrow.	Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica António Xavier, Portugal
2010 - 2014	Member of the Management Committee of COST Action CM0905 Organocatalysis (ORCA) Member	European Cooperation in Science and Technology, Belgium
1998 - 1999	PhD students representative at the Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa. Member	Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal

Conference scientific committee

	Conference name	Conference host
2007 - 2007	Glupor 7 - 7th International Meeting of the Portuguese Carbohydrate Group	SPQ - ITQB NOVA

Course / Discipline taught

	Academic session	Degree Subject (Type)	Institution / Organization
2019/11 - Current	PhD Program in Molecular Biosciences (MolBioS). Coordinator of the Curricular Unit Chemical Biology. Teaching of theoretical and tutorial classes of Curricular Unit Chemical Biology. Coordinator of the Curricular Unit Chemical Biology.	Biociências Moleculares (Doutoramento)	Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2017 - Current	Supervision of ITQB Summer Science School Students.	(Outros)	Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2014 - Current	Master in Biochemistry for Health (ITQB, FCT, FCM NOVA) Coordinator and Teaching of Drug Discovery, Design and Development curricular unit.	Bioquímica para a Saúde (Mestrado)	Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2010 - Current	Final project of Technician Degree, several students from Escola Secundária de Mem Martins	Organic Chemistry (Curso de Especialização Tecnológica)	Escola Secundária de Mem Martins, Portugal
2006 - Current	Final project of Technician Degree, several students from EPED (Escola Profissional de Educação para o Desenvolvimento).	Organic Chemistry (Curso de Especialização Tecnológica)	Escola Profissional de Educação para o Desenvolvimento, Portugal
2005 - Current	Supervision and demonstration of laboratory techniques in summer break occupational courses for secondary school students (Program Ciência Viva).	(Ensino secundário)	Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2022/01/01 - 2023/12	Coordinator of the curricular unit Anticancer Drug Discovery of the Master in Oncobiology, Molecular Mechanisms in Cancer at Faculdade de Medicina e Ciências Biomédicas, Universidade do Algarve.	Oncobiologia - Mecanismos Moleculares do Cancro (Mestrado integrado)	Universidade do Algarve, Portugal
2014 - 2019	CATSUS PhD Program (IST, FCUL, FCT/UC, IBB, UNL) Teaching of theoretical class Organocatalysis	CATSUS (Doutoramento)	Universidade de Lisboa Instituto Superior Técnico, Portugal
2018 - 2018	Invited Lecture in Asymmetric Synthesis 2, Master in Bioorganic Chemistry (FCT NOVA).	Química Bioorgânica (Mestrado)	Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2018 - 2018	Lecture in Biological Chemistry / Functionalization of Bioactive Compounds, Sustainable Chemistry PhD Program.	Química Sustentável (Doutoramento)	Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2007 - 2013	ITQB PhD course – Teaching of theoretical class “Organocatalysts”, Chemistry Tutorials “Carbohydrate Chemistry” and “Organocatalysis”	(Doutoramento)	Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2006 - 2008	Master in Green Chemistry, at the Faculdade de Ciências, Universidade de Lisboa, Teaching of theoretical classes for the course entitled Introductions to Green Chemistry Techniques	Química Verde (Mestrado)	Universidade de Lisboa Faculdade de Ciências, Portugal
2004 - 2008	Teaching of theoretical and practical classes for the course Organic Chemistry and Biochemistry as part of pre-graduated courses of Food Technology, Microbiology and Enviromental Quality Control at the Escola de Tecnologia e Gestão Industrial, Associação para a Escola Superior de Biotecnologia da Universidade Católica.	Organic Chemistry and Biochemistry (Curso de Especialização Tecnológica)	Universidade Católica Portuguesa, Portugal
2004 - 2008	Final project of Technician Degree, several students from ETGI (Escola de Tecnologia e Gestão Industrial, Associação para a Escola Superior de Biotecnologia da Universidade Católica)	Organic chemistry (Curso de Especialização Tecnológica)	Universidade Católica Portuguesa, Portugal
1999 - 2005	Masters in Food Technology/Quality Control, at the Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, Teaching of theoretical and practical classes for the course entitled The Chemistry of Food.	Tecnologia Alimentar e Qualidade (Mestrado)	Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Interview (newspaper / magazine)

	Activity description	Newspaper / Forum
2023/10/04	Opinion article for Público Newspaper: Um Nobel para a Interdisciplinaridade.	Jornal Público
2023/10/04	Expresso newspaper interview - Nobel da Química 2023.	Jornal Expresso
2021/10/06	Opinion article - Um Nobel para a química orgânica	Jornal Público
2021/10/06	Nobel distingue química "pura e dura" que mudou a produção de medicamentos.	Jornal Diário de Notícias

Interview (tv / radio show)

	Program	Topic
2023/06/10 - Current	Podcast Fala-me de ciência, Rádio Portalegre. Ep. 18 – Rita Ventura.
2021/10/06 - 2021/10/06	Telejornal RTP 1	Nobel da Química - Organocatálise Assimétrica permite criar fármacos mais baratos.
2020/07/22 - 2020/07/22	90 Segundos de Ciência - Antena 1 Radio Program	EP. 903 RITA VENTURA – GRUPO DE INVESTIGAÇÃO DESENVOLVE MOLÉCULAS CAPAZES DE ALTERAR A COMUNICAÇÃO DAS BACTÉRIAS
2012/11 - 2012/11	Com Ciência - RTP 2 TV Program	Extremochem presentation

Journal scientific committee

	Journal title (ISSN)	Publisher
2023/01/01 - Current	Frontiers in Catalysis	Frontiers
2013 - 2017	Asymmetric catalysis	De Gruyter

Other jury / evaluation

	Activity description	Institution / Organization
2000 - Current	Reviewer of Nature Communications, Scientific Reports, The Journal of Organic Chemistry, Carbohydrate Research, Bioorganic Chemistry, Journal of Biotechnology, PLOS ONE, Journal of Chemistry, Sustainable Chemistry and Pharmacy.
2019/06 - 2023/10	Member of the Chemistry evaluation panel of the 2019, 2020, 2021 and 2023 FCT PhD Grants Calls.	Fundação para a Ciência e a Tecnologia, Portugal
2022 - 2022	Reviewer of scientific projects Agence Nationale de la Recherche (ANR), France - Généric call for proposals 2022.

Distinctions

Award

2022	Prémio Investigação Científica em Ciências Militares 2022 na Área de Técnicas e Tecnologias Militares ao trabalho Estado-Maior-General das Forças Armadas, Portugal
2007	Prémio Câmara Pestana Instituto Bacteriológico Câmara Pestana, Portugal
2002	Prémio Estímulo à Investigação Científica, Fundação Calouste Gulbenkian. Fundação Calouste Gulbenkian, Portugal
1995	Prize Sociedade Farmacêutica Lusitana for the best final mark of the Faculties of Pharmacy Ordem dos Farmaceuticos, Portugal