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Celso Alves holds a degree in Marine Biology and Biotechnology and a Master's in Marine Resources Biotechnology attributed by the School of Tourism and Marine Technology of the Polytechnic of Leiria and a PhD in Marine Science, Technology and Sea Management (Do*Mar) attributed by the University of Aveiro. Currently, He also developed a Mini-MBA executive training program at the Leiria Bussiness School. He is contracted researcher at the Marine and Environmental Sciences Centre in the Polytechnic of Leiria pole and invited assistant Professor at the Polytechnic of Leiria. His scientific work has been focused in the the study of marine organisms, including seaweeds, bacteria and fungi, as well as plants, as source of new bioactive compounds with potential for biotechnological and therapeutic applications. He is co-author of 2 patents, 68 publications in scientific journals with peer review, 2 book, 12 book chapters, 30 abstracts published in scientific journals with peer review and more than 85 communications, including oral and poster communications, at international congresses. In this period, He participated as researcher in national and international competitive projects (±18M¿). He was awarded/ distinguished 11 times individually or as team member. He was part of the organizing committee of International Meeting on Marine Research in 3 editions (2016, 2018, 2020) and part of the local organizing committee of XVI International Symposium on Marine Natural Products & XI European Conference on Marine Natural Products, event that join two of the major conferences in marine natural products by the 2nd time in their history. He has also actively participated in activities related to experimental science teaching involving young students, such as "Open Science Day", "Semana Tanto Mar" and "I Jornadas da Ciência", through the accomplishment of workshops in marine biotechnology field, as well as, in different TV/ Radio programs/ magazines.
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Identification

Personal identification

Full name
Celso Alves

Citation names

  • Alves, Celso

Author identifiers

Ciência ID
501C-F268-2E60
ORCID iD
0000-0003-1581-2127
Scopus Author Id
ID: 55654969100

Knowledge fields

  • Medical and Health Sciences - Medical Biotechnology - Health-Related Biotechnology
Education
Degree Classification
2020/11/21 - 2021/09/22
Concluded
 Mini-MBA executive training program (Outros)
Leiria Business School, Portugal
2014/04/01 - 2019/11/08
Concluded
 Marine Science, Technology and Sea Management (Do*Mar) (Doutoramento)
Universidade de Aveiro, Portugal
"S. coronopifolius bromoterpenes: Antitumor activity and intracellular signal pathways characterization on in vitro human cellular cancer models" (THESIS/DISSERTATION)
2009 - 2011/12
Concluded
 Marine Resources Biotechnology (Mestrado)
Instituto Politécnico de Leiria Escola Superior de Turismo e Tecnologia do Mar de Peniche, Portugal
"Evaluation of cytotoxicity activity of macroalgae from Peniche coast (Portugal) on human tumor cells" (THESIS/DISSERTATION)
 19
2009/07/31
Concluded
 Marine Biology and Biotechnology (Licenciatura)
Instituto Politécnico de Leiria Escola Superior de Turismo e Tecnologia do Mar de Peniche, Portugal
"Evaluation of antioxidant and antiproliferative capacity of algae extracts from Peniche coast and Berlenga Nature Reserve" (THESIS/DISSERTATION)
Affiliation

Science

Category
Host institution 		Employer
2023/06/16 - Current Auxiliary Researcher (Research) Polytechnic University of Leiria, Portugal
2020/06/16 - 2023/06/15 Contracted Researcher (Research) Instituto Politécnico de Leiria, Portugal
2018/10/15 - 2020/06/15 Researcher (Research) Centro de Ciências do Mar e do Ambiente - Politécnico de Leiria, Portugal

Teaching in Higher Education

Category
Host institution 		Employer
2022/02/28 - 2023/07/31 Invited Assistant (Polytechnic Teacher) Instituto Politécnico de Leiria Escola Superior de Turismo e Tecnologia do Mar de Peniche, Portugal
Instituto Politécnico de Leiria Escola Superior de Turismo e Tecnologia do Mar de Peniche, Portugal
2021/02/22 - 2021/07/31 Invited Assistant (Polytechnic Teacher) Instituto Politécnico de Leiria Escola Superior de Turismo e Tecnologia do Mar de Peniche, Portugal
Instituto Politécnico de Leiria Escola Superior de Turismo e Tecnologia do Mar de Peniche, Portugal
2020/02/17 - 2020/07/17 Invited Assistant (Polytechnic Teacher) Instituto Politécnico de Leiria, Portugal
Instituto Politécnico de Leiria Escola Superior de Turismo e Tecnologia do Mar de Peniche, Portugal
2019/02/19 - 2019/07/19 Invited Assistant (Polytechnic Teacher) Instituto Politécnico de Leiria, Portugal
2018/02/19 - 2018/07/19 Invited Assistant (Polytechnic Teacher) Instituto Politécnico de Leiria, Portugal
2017/03/27 - 2017/07/19 Invited Assistant (Polytechnic Teacher) Instituto Politécnico de Leiria, Portugal

Others

Category
Host institution 		Employer
2020/04/27 - 2022/12/31 Researcher Volunteer - COVID 19 Diagnostic Center - Polytechnic Institute of Leiria, Portuguese Network of Laboratories for the COVID 19 Laboratory Diagnosis Instituto Politécnico de Leiria, Portugal
2014/04/01 - 2019/11/08 PhD student on Marine Science Technology and Sea Management Universidade de Aveiro, Portugal
Projects

Grant

Designation Funders
2014/04/01 - 2018/04/01 S. coronopifolius bromoterpenes: Antitumor activity and intracellular signal pathways characterization on in vitro human cellular cancer models
SFRH/BD/97764/2013
PhD Student Fellow
Centro de Ciências do Mar e do Ambiente - Politécnico de Leiria, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded

Contract

Designation Funders
2023/12 - Current BEAP-MAR - Blue Bioeconomy in the Atlantic Area: New Products from Marine Organisms
EAPA_0032/2022
Researcher
Ongoing
2022/01/18 - Current NEURONS - Natural products as key drivers in the development of nEUropROtective therapeutic ageNtS
FCT/DRI/ PNAAE 2021.09608.CBM
Researcher
Centro de Ciências do Mar e do Ambiente - Politécnico de Leiria, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2021/09/01 - Current MArTics - Marine bioactive compounds for neurological disorders therapeutics
FCT/DRI/CAPES 2019.00277.CBM
Researcher
Centro de Ciências do Mar e do Ambiente - Politécnico de Leiria, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2021/02/01 - Current ORCHESTRA - add-value to ORCHards through thE full valoriSaTion of macRoalgAe
nº 70155
Researcher
Centro de Ciências do Mar e do Ambiente - Politécnico de Leiria, Portugal
 COMPETE2020
Ongoing
2020 - Current DisCovEr+ . DesenvolvImento e otimização do diagnóStico COVid19 como resposta de EmeRgência à pandemia
-
Researcher
Centro de Ciências do Mar e do Ambiente - Politécnico de Leiria, Portugal
 COMPETE2020
Ongoing
2018/06/01 - Current CROSS-ATLANTIC – CReating Opportunities from Seaweed Sulfated polysaccharides for Application in Therapeutics
PTDC/BIA-OUT/29250/2017
Researcher
Instituto Politécnico de Leiria Instituto de Investigação Desenvolvimento e Estudos Avançados, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2017/01/01 - 2021/06/30 POINT4PAC – Precision oncology and innovative therapies and technologies
SAICTPAC/0019/2015 - LISBOA-01-0145-FEDER-016405
Researcher
Ongoing
2020/07/27 - 2020/10/27 Summer School "Exploration and Valorization of Marine Resources"
-
Researcher
Centro de Ciências do Mar e do Ambiente - Politécnico de Leiria, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2016/05/31 - 2019/11/30 Red2Discovery - The Red macro-algae Sphaerococcus coronopifolius and Asparagopsis armata as targets for marine drug Discovery
PTDC/MAR-BIO/6149/2014
Researcher
Instituto Politécnico de Leiria, Portugal
Ongoing
2016/01/01 - 2019/01/01 AMALIA - Algae-to-MArket Lab IdeAs
EASME/EMFF/2016/1.2.1.4/03/SI2.750419
Researcher
Concluded
2011/03/01 - 2014/03/31 BAMMBO- Sustainable production of Biologically Active Molecules of Marine Based Origin
Project nº 265896
Researcher
Concluded
2012/01/01 - 2014/01/01 FishTour – Uma experiência única na rota da sardinha de Peniche
PROMAR (Eixo 4 -GAC Oeste)
Researcher
Concluded
2010/01/01 - 2011/01/01 ALGELO: Produção de gelo suplementado com extratos de algas
QREN - BOLSAS DE IGNIÇÃO INOV.C (Mais Centro)
Researcher
Concluded
2009/01/01 - 2011/01/01 BlueAct: Pesquisa de compostos bioactivos em organismos marinhos da Reserva Natural das Berlengas e da costa de Peniche
Instituto Politécnico de Leiria
Researcher
Concluded
2010 - 2011 Algas edíveis da costa de Peniche: Identificação, caracterização e utilização gastronómica na região Oeste
-
Researcher
Instituto Politécnico de Leiria Instituto de Investigação Desenvolvimento e Estudos Avançados, Portugal
Concluded
Outputs

Publications

Book chapter
  1. Alves, Celso. "Biological Hazards and Natural Antimicrobials in Seafood". In Handbook of Seafood, Quality and Safety Maintenance and Applications. Novapublishers, 2016.
  2. Alves, Celso; Alves, C.; Pinteus, S.; Pedrosa, R.; Gil, M.M.. "Application of natural antimicrobials for seafood preservation". In Handbook of Seafood, Quality and Safety Maintenance and Applications. Novapublishers, 2016.
    Published
  3. Alves, Celso; Horta, A.; Alves, C.; Pinteus, S.; Pedrosa, R.. "The marine origin of drugs". In Phycotoxins: Chemistry and Biochemistry. John Wiley & Sons, 2015.
    Published • 10.1002/9781118500354.ch13
  4. Alves, Celso. "As algas como fonte de compostos bioativos". In Foro Iberoam. Rec. Mar. Acui. Edition Asociación Cultural Foro dos Recursos Mariños e da Acuicultura das Rías Galegas. 2012.
Journal article
  1. Santos, João M.; Jesus, Bárbara C.; Ribeiro, Helena; Martins, Alice; Marto, Joana; Fitas, Manuel; Pinto, Pedro; et al. "Extraction of macroalgae phenolic compounds for cosmetic application using eutectic solvents". Algal Research 79 (2024): 103438. http://dx.doi.org/10.1016/j.algal.2024.103438.
    Published • 10.1016/j.algal.2024.103438
  2. Perlikowska, Renata; Silva, Joana; Alves, Celso; Susano, Patricia; Zaklos-Szyda, Malgorzata; Skibska, Agnieszka; Adamska-Bartlomiejczyk, Anna; et al. "Neuroprotective and Anti-inflammatory Effects of Rubiscolin-6 Analogs with Proline Surrogates in Position 2". Neurochemical Research (2023): http://dx.doi.org/10.1007/s11064-023-04070-z.
    Published • 10.1007/s11064-023-04070-z
  3. Andreia Forte; Sandra Gago; Celso Alves; Joana Silva; Joana Alves; Rui Pedrosa; César A. T. Laia; Isabel M. Marrucho; Luis C. Branco. "Lanthanide-Based Organic Salts: Synthesis, Characterization, and Cytotoxicity Studies". Molecules (2023): https://doi.org/10.3390/molecules28207152.
    10.3390/molecules28207152
  4. Margarida Matias; Alice Martins; Celso Alves; Joana Silva; Susete Pinteus; Manuel Fitas; Pedro Pinto; et al. "New Insights into the Dermocosmetic Potential of the Red Seaweed Gelidium corneum". Antioxidants (2023): https://doi.org/10.3390/antiox12091684.
    10.3390/antiox12091684
  5. Joana Silva; Celso Alves; Francisca Soledade; Alice Martins; Susete Pinteus; Helena Gaspar; Maria Amparo Alfonso Rancaño; Rui Pedrosa. "Marine-Derived Components: Can They Be a Potential Therapeutic Approach to Parkinson’s Disease?". Marine Drugs (2023): https://www.mdpi.com/1660-3397/21/8/451.
    10.3390/md21080451
  6. Celso Alves; Marc Diederich. "Marine Natural Products as Anticancer Agents 2.0". Marine Drugs (2023): https://doi.org/10.3390/md21040247.
    10.3390/md21040247
  7. Martins, Alice; Alves, Celso; Silva, Joana; Pinteus, Susete; Gaspar, Helena; Pedrosa, Rui. "Sulfated Polysaccharides from Macroalgae—A Simple Roadmap for Chemical Characterization". Polymers 15 2 (2023): 399. http://dx.doi.org/10.3390/polym15020399.
    Published • 10.3390/polym15020399
  8. Alves, Celso; Silva, Joana; Pintéus, Susete; Guedes, Romina A.; Guedes, Rita C.; Alvariño, Rebeca; Freitas, Rafaela; et al. "Bromoditerpenes from the Red Seaweed Sphaerococcus coronopifolius as Potential Cytotoxic Agents and Proteasome Inhibitors and Related Mechanisms of Action". Marine Drugs 20 10 (2022): 652. http://dx.doi.org/10.3390/md20100652.
    10.3390/md20100652
  9. Perlikowska, Renata; Silva, Joana; Alves, Celso; Susano, Patrícia; Pedrosa, Rui. "The Therapeutic Potential of Naturally Occurring Peptides in Counteracting SH-SY5Y Cells Injury". International Journal of Molecular Sciences 23 19 (2022): 11778. http://dx.doi.org/10.3390/ijms231911778.
    Open access • Published • 10.3390/ijms231911778
  10. Susano, Patrícia; Silva, Joana; Alves, Celso; Martins, Alice; Pinteus, Susete; Gaspar, Helena; Goettert, Márcia Inês; Pedrosa, Rui. "Saccorhiza polyschides—A Source of Natural Active Ingredients for Greener Skincare Formulations". Molecules 27 19 (2022): 6496. http://dx.doi.org/10.3390/molecules27196496.
    Published • 10.3390/molecules27196496
  11. Silva, Joana; Alves, Celso; Susano, Patricia; Martins, Alice; Pinteus, Susete; Gaspar, Helena; Alfonso, Amparo; Pedrosa, Rui. "Exploring marine resources against neurological disorders– the neuroprotective and anti-inflammatory potential of the brown seaweed Bifurcaria bifurcata". Journal of Applied Phycology 34 5 (2022): 2671-2688. http://dx.doi.org/10.1007/s10811-022-02794-z.
    Published • 10.1007/s10811-022-02794-z
  12. Silva, Joana; Alvariño, Rebeca; Goettert, Márcia I.; Caruncho, Hector J.; Alves, Celso. "Editorial: Natural products as drivers in drug development for neurodegenerative disorders". Frontiers in Pharmacology 13 (2022): http://dx.doi.org/10.3389/fphar.2022.932179.
    Published • 10.3389/fphar.2022.932179
  13. De La Fuente, Gina; Pinteus, Susete; Silva, Joana; Alves, Celso; Pedrosa, Rui. "Antioxidant and antimicrobial potential of six Fucoids from the Mediterranean Sea and the Atlantic Ocean". Journal of the Science of Food and Agriculture (2022): http://dx.doi.org/10.1002/jsfa.11944.
    Published • 10.1002/jsfa.11944
  14. Matias, Margarida; Pinteus, Susete; Martins, Alice; Silva, Joana; Alves, Celso; Mouga, Teresa; Gaspar, Helena; Pedrosa, Rui. "Gelidiales Are Not Just Agar - Revealing the Antimicrobial Potential of Gelidium corneum for Skin Disorders". Antibiotics 11 4 (2022): 481. http://dx.doi.org/10.3390/antibiotics11040481.
    Published • 10.3390/antibiotics11040481
  15. Rehfeldt, Stephanie Cristine Hepp; Silva, Joana; Alves, Celso; Pinteus, Susete; Pedrosa, Rui; Laufer, Stefan; Goettert, Márcia Inês. "Neuroprotective Effect of Luteolin-7-O-Glucoside against 6-OHDA-Induced Damage in Undifferentiated and RA-Differentiated SH-SY5Y Cells". International Journal of Molecular Sciences 23 6 (2022): 2914. http://dx.doi.org/10.3390/ijms23062914.
    Published • 10.3390/ijms23062914
  16. Pinteus, Susete; Alves, Celso; Horta, André; Silva, Joana; Pedrosa, Rui. "Fucus spiralis tissue culture for sustainable phlorotannins production". Aquatic Botany 179 (2022): 103512. http://dx.doi.org/10.1016/j.aquabot.2022.103512.
    Published • 10.1016/j.aquabot.2022.103512
  17. Susano, Patrícia; Silva, Joana; Alves, Celso; Martins, Alice; Pinteus, Susete; Gaspar, Helena; Goettert, Márcia Ines; Pedrosa, Rui. "Mitigating the negative impacts of marine invasive species – Sargassum muticum - a key seaweed for skincare products development". Algal Research 62 (2022): 102634. http://dx.doi.org/10.1016/j.algal.2022.102634.
    Published • 10.1016/j.algal.2022.102634
  18. Pinteus, S; Susano, Patrícia; Alves, Celso; Silva, Joana; Martins, Alice; Pedrosa, Rui. "Seaweed role in Energetic Transition - From environmental pollution challenges to enhanced electrochemical devices". Biology (2022):
    Accepted
  19. Alves, Celso; Silva, Joana; Afonso, Marta B.; Guedes, Romina A.; Guedes, Rita C.; Alvariño, Rebeca; Pinteus, S; et al. "Disclosing the antitumor potential of the marine bromoditerpene sphaerococcenol A on distinct experimental cellular cancer models". Biomedicine & Pharmacotherapy (2022):
    Under revision
  20. Joana Alves; Helena Gaspar; Joana Silva; Celso Alves; Alice Martins; Fernando Teodoro; Patrícia Susano; Susete Pinteus; Rui Pedrosa. "Unravelling the Anti-Inflammatory and Antioxidant Potential of the Marine Sponge Cliona celata from the Portuguese Coastline". Marine Drugs (2021): https://doi.org/10.3390/md19110632.
    10.3390/md19110632
  21. Celso Alves; Marc Diederich. "Marine Natural Products as Anticancer Agents". Marine Drugs (2021): https://doi.org/10.3390/md19080447.
    10.3390/md19080447
  22. Calado, Maria da Luz; Silva, Joana; Alves, Celso; Susano, Patrícia; Santos, Débora; Alves, Joana; Martins, Alice; et al. "Marine endophytic fungi associated with Halopteris scoparia (Linnaeus) Sauvageau as producers of bioactive secondary metabolites with potential dermocosmetic application". PLoS ONE 16 5 (2021): e0250954. https://doi.org/10.1371/journal. pone.0250954.
    Open access • Published
  23. Celso Alves; Joana Silva; Susete Pinteus; Eva Alonso; Rebeca Alvariño; Adriana Duarte; Diorge Marmitt; et al. "Cytotoxic Mechanism of Sphaerodactylomelol, an Uncommon Bromoditerpene Isolated from Sphaerococcus coronopifolius". Molecules (2021): https://doi.org/10.3390/molecules26051374.
    10.3390/molecules26051374
  24. Silva, Joana; Alves, Celso; Pinteus, Susete; Susano, Patrícia; Simões, Marco; Guedes, Miguel; Martins, Alice; et al. "Disclosing the potential of eleganolone for Parkinson’s disease therapeutics: Neuroprotective and anti-inflammatory activities". Pharmacological Research (2021): 105589. http://dx.doi.org/10.1016/j.phrs.2021.105589.
    In press • 10.1016/j.phrs.2021.105589
  25. Susano, Patrícia; Silva, Joana; Alves, Celso; Martins, Alice; Gaspar, Helena; Pinteus, Susete; Mouga, Teresa; et al. "Unravelling the Dermatological Potential of the Brown Seaweed Carpomitra costata". Marine Drugs 19 3 (2021): 135. http://dx.doi.org/10.3390/md19030135.
    Published • 10.3390/md19030135
  26. Joana Silva; Celso Alves; Alice Martins; Patrícia Susano; Marco Simões; Miguel Guedes; Stephanie Rehfeldt; et al. "Loliolide, a New Therapeutic Option for Neurological Diseases? In Vitro Neuroprotective and Anti-Inflammatory Activities of a Monoterpenoid Lactone Isolated from Codium tomentosum". International Journal of Molecular Sciences 22 4 (2021): 1888-1888. https://doi.org/10.3390/ijms22041888.
    Published • 10.3390/ijms22041888
  27. Carina Félix; Rafael Félix; Ana M. Carmona; Adriana P. Januário; Pedro D.M. Dias; Tânia F.L. Vicente; Joana Silva; et al. "Cosmeceutical Potential of Grateloupia turuturu: Using Low-Cost Extraction Methodologies to Obtain Added-Value Extracts". Applied Sciences 11 4 (2021): 1650-1650. https://doi.org/10.3390/app11041650.
    10.3390/app11041650
  28. Blanca de Juan Mora; Luís Filipe; Andreia Forte; Miguel M. Santos; Celso Alves; Fernando Teodoro; Rui Pedrosa; et al. "Boosting Antimicrobial Activity of Ciprofloxacin by Functionalization of Mesoporous Silica Nanoparticles". Pharmaceutics 13 2 (2021): 218-218. https://doi.org/10.3390/pharmaceutics13020218.
    10.3390/pharmaceutics13020218
  29. Pinteus, Susete; Lemos, Marco F.L.; Alves, Celso; Silva, Joana; Pedrosa, Rui. "The marine invasive seaweeds Asparagopsis armata and Sargassum muticum as targets for greener antifouling solutions". Science of The Total Environment 750 (2021): 141372. http://dx.doi.org/10.1016/j.scitotenv.2020.141372.
    10.1016/j.scitotenv.2020.141372
  30. Andreia Forte; Sandra Gago; Manuela Ribeiro Carrott; Peter Carrott; Celso Alves; Fernando Teodoro; Rui Pedrosa; Isabel M. Marrucho; Luis C. Branco. "Mesoporous silica nanoparticles with manganese and lanthanide salts: synthesis, characterization and cytotoxicity studies". Dalton Transactions (2021): https://doi.org/10.1039/D1DT00605C.
    10.1039/D1DT00605C
  31. Diogo Madeira; Celso Alves; Joana Silva; Catarina Florindo; Alexandra Costa; Željko Petrovski; Isabel M. Marrucho; et al. "Fluoroquinolone-Based Organic Salts and Ionic Liquids as Highly Bioavailable Broad-Spectrum Antimicrobials". Proceedings (2020): https://doi.org/10.3390/IECP2020-08649.
    10.3390/IECP2020-08649
  32. Pinteus, Susete; Lemos, Marco F.L.; Simões, Marco; Alves, Celso; Silva, Joana; Gaspar, Helena; Martins, Alice; Rodrigues, Américo; Pedrosa, Rui. "Marine invasive species for high-value products' exploration – Unveiling the antimicrobial potential of Asparagopsis armata against human pathogens". Algal Research 52 (2020): 102091. http://dx.doi.org/10.1016/j.algal.2020.102091.
    Published • 10.1016/j.algal.2020.102091
  33. Joana Silva; Alice Martins; Celso Alves; Susete Pinteus; Helena Gaspar; Amparo Alfonso; Rui Pedrosa. "Natural Approaches for Neurological Disorders—The Neuroprotective Potential of Codium tomentosum". Molecules 25 22 (2020): 5478-5478. https://doi.org/10.3390/molecules25225478.
    10.3390/molecules25225478
  34. Alves, Celso; Serrano, Eurico; Silva, Joana; Rodrigues, Carlos; Pinteus, Susete; Gaspar, Helena; Botana, Luis M.; Alpoim, Maria C.; Pedrosa, Rui. "Sphaerococcus coronopifolius bromoterpenes as potential cancer stem cell-targeting agents". Biomedicine & Pharmacotherapy 128 (2020): 110275. http://dx.doi.org/10.1016/j.biopha.2020.110275.
    Published • 10.1016/j.biopha.2020.110275
  35. Santos, Miguel M.; Alves, Celso; Silva, Joana; Florindo, Catarina; Costa, Alexandra; Petrovski, Željko; Marrucho, Isabel M.; Pedrosa, Rui; Branco, Luís C.. "Antimicrobial Activities of Highly Bioavailable Organic Salts and Ionic Liquids from Fluoroquinolones". Pharmaceutics 12 8 (2020): 694. http://dx.doi.org/10.3390/pharmaceutics12080694.
    Published • 10.3390/pharmaceutics12080694
  36. Silva, Joana; Alves, Celso; Pinteus, Susete; Mendes, Susana; Pedrosa, Rui. "Seaweeds’ neuroprotective potential set in vitro on a human cellular stress model". Molecular and Cellular Biochemistry (2020): http://dx.doi.org/10.1007/s11010-020-03824-5.
    Published • 10.1007/s11010-020-03824-5
  37. Freitas, Rafaela; Martins, Alice; Silva, Joana; Alves, Celso; Pinteus, Susete; Alves, Joana; Teodoro, Fernando; et al. "Highlighting the Biological Potential of the Brown Seaweed Fucus spiralis for Skin Applications". Antioxidants 9 7 (2020): 611. http://dx.doi.org/10.3390/antiox9070611.
    Published • 10.3390/antiox9070611
  38. Majolo, Fernanda; Bitencourt, Shanna; Wissmann Monteiro, Bruna; Viegas Haute, Gabriela; Alves, Celso; Silva, Joana; Pinteus, Susete; et al. "Antimicrobial and antileukemic effects: in vitro activity of Calyptranthes grandifolia aqueous leaf extract". Journal of Toxicology and Environmental Health, Part A (2020): 1-13. http://dx.doi.org/10.1080/15287394.2020.1753606.
    Published • 10.1080/15287394.2020.1753606
  39. Pinteus, Susete; Lemos, Marco F.L.; Freitas, Rafaela; Duarte, Inês M.; Alves, Celso; Silva, Joana; Marques, Sónia C.; Pedrosa, Rui. "Medusa polyps adherence inhibition: A novel experimental model for antifouling assays". Science of The Total Environment (2020): 136796. http://dx.doi.org/10.1016/j.scitotenv.2020.136796.
    Published • 10.1016/j.scitotenv.2020.136796
  40. Diorge Jonatas Marmitt; Celso Alves; Joana Silva; Susete Pinteus; Taiane Schneider; Roberto Christ Vianna Santos; Elisete Maria de Freitas; et al. "Neuroprotective potential of Myrciaria plinioides D. Legrand extract in an in vitro human neuroblastoma model". Inflammopharmacology (2019): https://doi.org/10.1007/s10787-019-00652-y.
    10.1007/s10787-019-00652-y
  41. Silva, J. Paulo; Alves, Celso; Pinteus, Susete; Silva, Joana; Valado, Ana; Pedrosa, Rui; Pereira, Leonel. "Antioxidant and antitumor potential of wild and IMTA-cultivated Osmundea pinnatifida". Journal of Oceanology and Limnology 37 3 (2019): 825-835. http://dx.doi.org/10.1007/s00343-019-8110-4.
    10.1007/s00343-019-8110-4
  42. André Horta; Celso Alves; Susete Pinteus; Cláudia Lopes; Nádia Fino; Joana Silva; Joana Ribeiro; et al. "Identification of Asparagopsis armata -associated bacteria and characterization of their bioactive potential". MicrobiologyOpen (2019): e00824-e00824. https://doi.org/10.1002/mbo3.824.
    10.1002/mbo3.824
  43. Silva, Joana; Alves, Celso; Freitas, Rafaela; Martins, Alice; Pinteus, Susete; Ribeiro, Joana; Gaspar, Helena; Alfonso, Amparo; Pedrosa, Rui. "Antioxidant and Neuroprotective Potential of the Brown Seaweed Bifurcaria bifurcata in an in vitro Parkinson’s Disease Model". Marine Drugs 17 2 (2019): 85. http://dx.doi.org/10.3390/md17020085.
    10.3390/md17020085
  44. Alves, C.; Silva, J.; Pinteus, S.; Gaspar, H.; Alpoim, M.C.; Botana, L.M.; Pedrosa, R.. "From marine origin to therapeutics: The antitumor potential of marine algae-derived compounds". Frontiers in Pharmacology 9 AUG (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85054932428&partnerID=MN8TOARS.
    10.3389/fphar.2018.00777
  45. Pinteus, S.; Lemos, M.F.L.; Alves, C.; Neugebauer, A.; Silva, J.; Thomas, O.P.; Botana, L.M.; Gaspar, H.; Pedrosa, R.. "Marine invasive macroalgae: Turning a real threat into a major opportunity - the biotechnological potential of Sargassum muticum and Asparagopsis armata". Algal Research 34 (2018): 217-234. http://www.scopus.com/inward/record.url?eid=2-s2.0-85051132236&partnerID=MN8TOARS.
    10.1016/j.algal.2018.06.018
  46. Dörr, J.A.; Bitencourt, S.; Bortoluzzi, L.; Alves, C.; Silva, J.; Stoll, S.; Pinteus, S.; et al. "In vitro activities of Ceiba speciosa (A.St.-Hil) Ravenna aqueous stem bark extract". Natural Product Research (2018): 1-4. http://www.scopus.com/inward/record.url?eid=2-s2.0-85047337380&partnerID=MN8TOARS.
    10.1080/14786419.2018.1478823
  47. Silva, J.; Alves, C.; Pinteus, S.; Mendes, S.; Pedrosa, R.. "Neuroprotective effects of seaweeds against 6-hydroxidopamine-induced cell death on an in vitro human neuroblastoma model". BMC Complementary and Alternative Medicine 18 1 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85042119141&partnerID=MN8TOARS.
    10.1186/s12906-018-2103-2
  48. Souza, R.B.; Frota, A.F.; Silva, J.; Alves, C.; Neugebauer, A.Z.; Pinteus, S.; Rodrigues, J.A.G.; et al. "In vitro activities of kappa-carrageenan isolated from red marine alga Hypnea musciformis: Antimicrobial, anticancer and neuroprotective potential". International Journal of Biological Macromolecules 112 (2018): 1248-1259. http://www.scopus.com/inward/record.url?eid=2-s2.0-85042303681&partnerID=MN8TOARS.
    10.1016/j.ijbiomac.2018.02.029
  49. Alves, C.; Pinteus, S.; Rodrigues, A.; Horta, A.; Pedrosa, R.. "Algae from Portuguese Coast Presented High Cytotoxicity and Antiproliferative Effects on an in vitro Model of Human Colorectal Cancer". Pharmacognosy Research 10 1 (2018): 24-30. http://www.scopus.com/inward/record.url?eid=2-s2.0-85042525007&partnerID=MN8TOARS.
    10.4103/pr.pr_151_16
  50. Susete Pinteus; Marco Lemos; Joana Silva; Celso Alves; Agnieszka Neugebauer; Rafaela Freitas; Adriana Duarte; Rui Pedrosa. "An Insight into Sargassum muticum Cytoprotective Mechanisms against Oxidative Stress on a Human Cell In Vitro Model". Marine Drugs (2017):
    10.3390/md15110353
  51. Pinteus, S.; Silva, J.; Alves, C.; Horta, A.; Thomas, O.P.; Pedrosa, R.. "Antioxidant and cytoprotective activities of fucus spiralis seaweed on a human cell in vitro model". International Journal of Molecular Sciences 18 2 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85011101721&partnerID=MN8TOARS.
    10.3390/ijms18020292
  52. Pinteus, S.; Silva, J.; Alves, C.; Horta, A.; Fino, N.; Rodrigues, A.I.; Mendes, S.; Pedrosa, R.. "Cytoprotective effect of seaweeds with high antioxidant activity from the Peniche coast (Portugal)". Food Chemistry 218 (2017): 591-599. http://www.scopus.com/inward/record.url?eid=2-s2.0-84988643257&partnerID=MN8TOARS.
    10.1016/j.foodchem.2016.09.067
  53. Alves, Celso. "Lymphocyte genotoxicity and protective effect of Calyptranthes tricona (Myrtaceae) against H2O2-induced cell death in MCF-7 cells". Molecular and Cellular Biochemistry (2016): http://dx.doi.org/10.1007/s11010-016-2840-9.
    10.1007/s11010-016-2840-9
  54. Alves, C.; Pinteus, S.; Horta, A.; Pedrosa, R.. "High cytotoxicity and anti-proliferative activity of algae extracts on an in vitro model of human hepatocellular carcinoma". SpringerPlus 5 1 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84981531887&partnerID=MN8TOARS.
    10.1186/s40064-016-2938-2
  55. Alves, C.; Pinteus, S.; Simões, T.; Horta, A.; Silva, J.; Tecelão, C.; Pedrosa, R.. "Bifurcaria bifurcata: a key macro-alga as a source of bioactive compounds and functional ingredients". International Journal of Food Science and Technology 51 7 (2016): 1638-1646. http://www.scopus.com/inward/record.url?eid=2-s2.0-84974724308&partnerID=MN8TOARS.
    10.1111/ijfs.13135
  56. Kich, D.M.; Bitencourt, S.; Alves, C.; Silva, J.; Pinteus, S.; Pedrosa, R.; Laufer, S.; de Souza, C.F.V.; Goettert, M.I.. "Neuromodulatory effects of Calyptranthes grandifolia extracts against 6-hydroxydopamine-induced neurotoxicity in SH-SY5Y cells". Biomedicine and Pharmacotherapy 84 (2016): 382-386. http://www.scopus.com/inward/record.url?eid=2-s2.0-84988584432&partnerID=MN8TOARS.
    10.1016/j.biopha.2016.09.063
  57. Chambel, J.; Horta, A.; Alves, C.; Pinteus, S.; Severiano, V.; Pedrosa, R.. "Can a freshwater aquaculture model be used for marine drug discovery?". Aquaculture Research 47 11 (2016): 3689-3693. http://www.scopus.com/inward/record.url?eid=2-s2.0-84929191416&partnerID=MN8TOARS.
    10.1111/are.12794
  58. Santos, R.; Dias, S.; Pinteus, S.; Silva, J.; Alves, C.; Tecelão, C.; Pedrosa, R.; Pombo, A.. "Sea cucumber Holothuria forskali, a new resource for aquaculture? Reproductive biology and nutraceutical approach". Aquaculture Research 47 7 (2016): 2307-2323. http://www.scopus.com/inward/record.url?eid=2-s2.0-84921516379&partnerID=MN8TOARS.
    10.1111/are.12683
  59. Pinteus, S.; Alves, C.; Monteiro, H.; Araújo, E.; Horta, A.; Pedrosa, R.. "Asparagopsis armata and Sphaerococcus coronopifolius as a natural source of antimicrobial compounds". World Journal of Microbiology and Biotechnology 31 3 (2015): 445-451. http://www.scopus.com/inward/record.url?eid=2-s2.0-84925501819&partnerID=MN8TOARS.
    10.1007/s11274-015-1797-2
  60. Rodrigues, D.; Alves, C.; Horta, A.; Pinteus, S.; Silva, J.; Culioli, G.; Thomas, O.P.; Pedrosa, R.. "Antitumor and antimicrobial potential of bromoditerpenes isolated from the Red Alga, Sphaerococcus coronopifolius". Marine Drugs 13 2 (2015): 713-726. http://www.scopus.com/inward/record.url?eid=2-s2.0-84923172411&partnerID=MN8TOARS.
    10.3390/md13020713
  61. Santos, Rita; Dias, Simaura; Pinteus, Susete; Silva, Joana; Alves, Celso; Tecelão, Carla; Pombo, Ana; Pedrosa, Rui. "The Biotechnological and Seafood Potential of Stichopus regalis". Advances in Bioscience and Biotechnology 06 03 (2015): 194-204. http://dx.doi.org/10.4236/abb.2015.63019.
    10.4236/abb.2015.63019
  62. Horta, A.; Pinteus, S.; Alves, C.; Fino, N.; Silva, J.; Fernandez, S.; Rodrigues, A.; Pedrosa, R.. "Antioxidant and antimicrobial potential of the Bifurcaria bifurcata epiphytic bacteria". Marine Drugs 12 3 (2014): 1676-1689. http://www.scopus.com/inward/record.url?eid=2-s2.0-84897084024&partnerID=MN8TOARS.
    10.3390/md12031676
  63. Murray, P.M.; Moane, S.; Collins, C.; Beletskaya, T.; Thomas, O.P.; Duarte, A.W.F.; Nobre, F.S.; et al. "Sustainable production of biologically active molecules of marine based origin". New Biotechnology 30 6 (2013): 839-850. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884204082&partnerID=MN8TOARS.
    10.1016/j.nbt.2013.03.006
Thesis / Dissertation
  1. Alves, Celso. "Avaliação da capacidade citotóxica de macroalgas da costa de Peniche (Portugal) em células tumorais humanas". Master, Instituto Politécnico de Leiria, 2011.

Intellectual property

Patent
  1. Alves, Celso; Silva, Joana; Pinteus, S; Martins, Alice; Freitas, Rafaela; Pedrosa, Rui. 2022. "PROCESS FOR OBTAINING EXTRACT ENRICHED IN FLOROTANINS AND EXTRACT ENRICHED IN FLOROTANINS WITH ANTI-ENZYMATIC ACTION FOR USE IN DERMATOLOGY". Portugal.
    Granted/Issued
  2. Pedrosa, R.; Alves, Celso; Pinteus, S.; Monteiro, H.R.; Rodrigues, A.; Araújo, E.. 2009. "Ice supplemented with algae and/or derivates, process for obtaining thereof and applications thereof".
Activities

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2019 - 2019 Member of local organising committee of XVI International Symposium on Marine Natural Products & XI European Conference on Marine Natural Products taken place in Peniche, Portugal (2019 - 2019)
Conference (Member of the Organising Committee)
 Instituto Politécnico de Leiria, Portugal
2018 - 2018 Member of organising committee of International Meeting on Marine Research (IMMR’18) taken place in Peniche, Portugal (2018 - 2018)
Conference (Member of the Organising Committee)
 Instituto Politécnico de Leiria Escola Superior de Turismo e Tecnologia do Mar de Peniche, Portugal
2016 - 2016 Member of organising committee of International Meeting on Marine Research (IMMR’16) taken place in Peniche, Portugal (2016 - 2016)
Conference (Member of the Organising Committee)
 Instituto Politécnico de Leiria Escola Superior de Turismo e Tecnologia do Mar de Peniche, Portugal
2014 - 2014 Member of organising committee of International Meeting on Marine Research (IMMR’14) taken place in Peniche, Portugal (2014 - 2014)
Congress (Member of the Organising Committee)
 Instituto Politécnico de Leiria Escola Superior de Turismo e Tecnologia do Mar de Peniche, Portugal
2011/04/15 - 2011/04/19 Member of organising committee of "XIV Encontro Nacional de Estudantes de Biologia" taken place in Peniche, Portugal (2011/04/15 - 2011/04/19)
Conference (Member of the Organising Committee)
 Instituto Politécnico de Leiria Escola Superior de Turismo e Tecnologia do Mar de Peniche, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2020/02/10 - 2020/02/11 Conducting a workshop in collaboration with the organization of "Ocean Open Day” developed in School of Tourism and Marine Technology, Polytechnic of Leiria with the theme "Seaweeds and therapeutics and biotechnology applications"
Workshop
 Ocean Open Day
Instituto Politécnico de Leiria Escola Superior de Turismo e Tecnologia do Mar de Peniche, Portugal
2019/09/06 - 2019/09/06 Conducting a workshop in collaboration with the organization of "Semana Tanto Mar 2019 - Atividades Laboratoriais” developed in School of Tourism and Marine Technology, Polytechnic of Leiria with the theme "From the sea to society - the potential of macroalgae preventing the development of different pathologies".
Workshop
 Semana Tanto Mar
Instituto Politécnico de Leiria Escola Superior de Turismo e Tecnologia do Mar de Peniche, Portugal
2019/03/14 - 2019/03/14 Conducting a workshop in collaboration with the organization of "I Jornadas da Ciência subordinada ao tema Ciência –Concentra o teu Conhecimento”” developed in Science School of the University of Minho with the theme "From the sea to society - the potential of seaweeds as source of new bioactive compounds"
Workshop
 I Jornadas da Ciência subordinada ao tema "Ciência –Concentra o teu Conhecimento””
Universidade do Minho Escola de Ciências, Portugal
2019/02/04 - 2019/02/08 Conducting a workshop in collaboration with the organization of "Ocean Open Day” developed in School of Tourism and Marine Technology, Polytechnic of Leiria with the theme "Seaweeds as source of bioactive compounds with therapeutic and biotechnology application".
Workshop
 Ocean Open Day
Instituto Politécnico de Leiria Escola Superior de Turismo e Tecnologia do Mar de Peniche, Portugal
2018/09/01 - 2018/09/06 Conducting a workshop in collaboration with the organization of "Semana Tanto Mar 2018 - Atividades Laboratoriais” developed in School of Tourism and Marine Technology, Polytechnic of Leiria.
Workshop
 Semana Tanto Mar
Instituto Politécnico de Leiria Escola Superior de Turismo e Tecnologia do Mar de Peniche, Portugal
2018/02/13 - 2018/02/17 Conducting a workshop in collaboration with the organization of "Ocean Open Day” developed in School of Tourism and Marine Technology, Polytechnic of Leiria with the theme "Seaweeds as source of bioactive compounds with therapeutic and biotechnology application".
Workshop
 Ocean Open Day
Instituto Politécnico de Leiria Escola Superior de Turismo e Tecnologia do Mar de Peniche, Portugal
2015/08/31 - 2015/09/07 Conducting a workshop in collaboration with the organization of "Semana Tanto Mar 2015 - Atividades Laboratoriais” developed in School of Tourism and Marine Technology, Polytechnic of Leiria.
Workshop
 Semana Tanto Mar
Instituto Politécnico de Leiria Escola Superior de Turismo e Tecnologia do Mar de Peniche, Portugal
2014/09/01 - 2014/09/08 Conducting a workshop in collaboration with the organization of "Semana Tanto Mar 2014 - Atividades Laboratoriais” developed in School of Tourism and Marine Technology, Polytechnic of Leiria.
Workshop
 Semana Tanto Mar
Instituto Politécnico de Leiria Escola Superior de Turismo e Tecnologia do Mar de Peniche, Portugal
2013/09/01 - 2013/09/08 Conducting a workshop in collaboration with the organization of "Semana Tanto Mar 2013 - Atividades Laboratoriais” developed in School of Tourism and Marine Technology, Polytechnic of Leiria.
Workshop
 Semana Tanto Mar
Instituto Politécnico de Leiria Escola Superior de Turismo e Tecnologia do Mar de Peniche, Portugal
2013/07/08 - 2013/07/26 Collaborating researcher in the Ciência Viva Program in the laboratory developed in School of Tourism and Marine Technology, Polytechnic of Leiria with the theme " Biotechnological applicatiosn of marine resources - seaweeds"
Other
 The Programme - Ciência Viva - Science for Young People in the Holidays
Instituto Politécnico de Leiria Escola Superior de Turismo e Tecnologia do Mar de Peniche, Portugal
2012/09/01 - 2012/09/08 Conducting a workshop in collaboration with the organization of "Semana Tanto Mar 2012 - Atividades Laboratoriais” developed in School of Tourism and Marine Technology, Polytechnic of Leiria.
Workshop
 Semana Tanto Mar
Instituto Politécnico de Leiria Escola Superior de Turismo e Tecnologia do Mar de Peniche, Portugal
2012/07/09 - 2012/07/20 Collaborating researcher in the Ciência Viva Program in the laboratory developed in School of Tourism and Marine Technology, Polytechnic of Leiria with the theme " Biotechnological applicatiosn of marine resources - seaweeds"
Other
 The Programme - Ciência Viva - Science for Young People in the Holidays
Instituto Politécnico de Leiria Escola Superior de Turismo e Tecnologia do Mar de Peniche, Portugal

Interview (tv / radio show)

Program Topic
2020/02/28 - 2020/02/28 90 segundos de ciência Extrato de macroalgas para desenvolver compostos capazes de aumentar o tempo de prateleira de refeições pré-preparadas como saladas ou fruta fatiada
2018/06/06 - 2018/06/06 Portugal em Direto (3m40s - 3m55s) Projeto Red2Discovery
2015/03/26 - 2015/03/26 TSF -Um Mar de Experiências Um Mar de Experiências
2014/10/31 - 2014/10/31 Economia Verde (1m45s - 2m20s) Valorizar os recursos marinhos em Peniche

Other jury / evaluation

Activity description Institution / Organization
2020/04/16 - 2021/06/21 Special Issue Editor of Marine Drugs journal. Special Issue "Marine Natural Products as Anticancer Agents". Marine Drugs_MDPI, Switzerland
Distinctions

Award

2018 Green Project Awards - Category "MAR"_ AMALIA – “Algae-to-market lab ideas" project - Member of Research team
2016 Poster communication distinguished with "Prémio SBBQ"
2016 2nd Youth Gala of Municipio de Peniche. Winner in the category "Professions"
2015 Documentary "Fishtour - Uma Experiência na Rota da Sardinha" Winner in the category "Special Award of the Director of the Festival"
2015 Documentary "Fishtour - Uma Experiência na Rota da Sardinha". Winner in the category "Vida Humana"
2009 University Award Lotaçor 2008/2009

Other distinction

2016 Highly Cited Research
2010 Merit Scholarship
Instituto Politécnico de Leiria, Portugal