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Sandra Rebelo (SR) is Assistant Professor at the Department of Medical Sciences of the University of Aveiro (UA) where she lectures cell biology and cell division as well as cell models of neurodegenerative diseases and is vice-Director of BSc in Biomedical Sciences. SR also integrates the Department of Medical Sciences Council, the Ethics Board of the Department of Medical Sciences and the Advisory Council of the Institute for Education and Citizenship (IEC). Principal Investigator at Institute of Biomedicine (iBiMED) ¿ Molecular basis of Neuropatologies, she is also Coordinator of the iBiMED Animal Facility. SR is graduated in Biology by the University of Aveiro, she obtained the MSc degree in Molecular Microbiology and holds a PhD in Biochemistry (Molecular and Cellular Neuroscience area) from University of Aveiro/ Erlangen University. SR has participated in several national and international funded projects, in the role of PI, Co-PI, WP leader or team member. Currently she is the PI of protect ¿Development of BRI2-based therapies for neurodegenerative diseases (proof of concept)¿, co-PI of project WISDOM - Impact of wide-spread proteome aggregation through aging in mammals and implications for the development of age-related diseases¿, WP leader in ¿PAGE- Protein aggregation across the lifespan¿, and researcher in ¿Goback- New therapeutic targets for spinal cord regeneration¿ and ¿Synaptic networks and Personalized Medicine Approaches to Understand Neurobehavioural Diseases Across the Lifespan¿ FCT projects. SR published 50 peer-reviewed papers (822 citations; h-index=18), 5 book chapters and 8 conference papers, and has received several research and personal awards. SR supervises/ed 3 Post-doctorates, 4 PhD, 25 MSc and 22 BSc students. Her current research interests are molecular mechanisms underlying Myotonic Dystrophy type 1, BRI2 signalling pathways and its impact on AD, BRI2-based therapeutics, personalized therapeutics, gene and cell therapies.
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Identification

Personal identification

Full name
Sandra Maria Tavares da Costa Rebelo

Citation names

  • Rebelo, Sandra
  • Rebelo, S.

Author identifiers

Ciência ID
5114-66B6-0B56
ORCID iD
0000-0002-5862-5797
Researcher Id
ResearcherID: B-8973-2008

Email addresses

  • srebelo@ua.pt (Professional)

Telephones

Telephone
  • 234247245 Ext.: 22123 (Professional)

Addresses

  • Universidade de Aveiro . Universidade de Aveiro, Campus de Santiago, Edifício 30 Agra do Crasto, 3810-193, Aveiro, Aveiro, Portugal (Professional)

Websites

Knowledge fields

  • Medical and Health Sciences - Basic Medicine - Neurosciences
  • Natural sciences - Biological Sciences - Cell Biology
  • Natural sciences - Biological Sciences - Molecular Biology
  • Natural sciences - Biological Sciences - Biochemistry
  • Medical and Health Sciences - Medical Biotechnology

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Proficiency (C2) Advanced (C1) Advanced (C1) Proficiency (C2)
Spanish; Castilian Elementary (A2) Elementary (A2) Elementary (A2) Elementary (A2) Elementary (A2)
French Elementary (A2) Elementary (A2) Elementary (A2) Elementary (A2) Elementary (A2)
Education
Degree Classification
2004/09/01 - 2008/04/29
Concluded
 Bioquímica (Doutoramento)
Major in Neurosciences
Universidade de Aveiro, Portugal

Universitätsklinikum Erlangen, Germany
"The role of the NPTY functional domain on APP trafficking and processing" (THESIS/DISSERTATION)
 Unanimity approved with honours
2001 - 2003
Concluded
 Microbiologia Molecular (Mestrado)
Major in Molecular Mechanisms of Alzheimer’s Disease
Universidade de Aveiro, Portugal
"Effect of cell density on the expression of the Alzheimer’s amyloid precursor protein" (THESIS/DISSERTATION)
 Aproved
1996/09/15 - 2000/07/25
Concluded
 Biologia (Licenciatura)
Major in Científico
Universidade de Aveiro, Portugal
"Effect of cell density on the expression of the Alzheimer’s amyloid precursor protein’" (THESIS/DISSERTATION)
 15
Affiliation

Science

Category
Host institution 		Employer
2015/01/01 - Current Principal Investigator (Research) Universidade de Aveiro Instituto de Biomedicina, Portugal
Universidade de Aveiro Instituto de Biomedicina, Portugal
2009/03/01 - 2011/04/30 Postdoc (Research) Fundação para a Ciência e a Tecnologia, Portugal
Icahn School of Medicine at Mount Sinai, United States
(...)
2008/06/14 - 2008/12/14 Postdoc (Research) Universidade de Aveiro, Portugal
Universidade de Aveiro, Portugal
2003/09/01 - 2004/08/31 Research Assistant (Research) Universidade de Aveiro Departamento de Biologia, Portugal
Universidade de Aveiro, Portugal
2001/06/01 - 2003/05/31 Research Assistant (Research) Universidade de Aveiro Departamento de Biologia, Portugal
Universidade de Aveiro, Portugal
2000/09/01 - 2001/05/31 Research Trainee (Research) Universidade de Aveiro, Portugal
Universidade de Aveiro, Portugal

Teaching in Higher Education

Category
Host institution 		Employer
2020/06/01 - Current Assistant Professor (University Teacher) Universidade de Aveiro, Portugal
2015/09/01 - 2020/05/31 Invited Assistant Professor (University Teacher) Universidade de Aveiro, Portugal
Universidade de Aveiro, Portugal
2008/09/15 - 2015/08/31 Invited Assistant Professor (University Teacher) Universidade de Aveiro, Portugal
Universidade de Aveiro, Portugal
2003/10/01 - 2005/02/28 Trainee Assistant (University Teacher) Universidade de Aveiro Departamento de Biologia, Portugal

Positions / Appointments

Category
Host institution 		Employer
2020/12/28 - Current Coordinator of Microsurgery and Experimental Surgery Unit Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2020/06/01 - Current Member of the commitee for Pedagogical Innovation andQuality Universidade de Aveiro Departamento de Ciências Médicas, Portugal
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2017/11/01 - Current Council Member of the Department of Medical Sciences (DCM) Universidade de Aveiro Departamento de Ciências Médicas, Portugal
Universidade de Aveiro, Portugal
2015/03/01 - Current Head of the Animal Facility iBiMED/ DCM Universidade de Aveiro Departamento de Ciências Médicas, Portugal
Universidade de Aveiro, Portugal
2015/01/01 - Current Member of the Scientific Council of the Institute of Biomedicine (iBiMED) Universidade de Aveiro Instituto de Biomedicina, Portugal
Universidade de Aveiro, Portugal
2013/01/01 - Current Leader Research Group- Molecular basis of Neuropatologies Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2011/07/27 - Current Researcher- Coordinator for the Pratice of Animal Experimentation Universidade de Aveiro, Portugal
Universidade de Aveiro, Portugal
2018/10/01 - 2022/12/31 Member of Ethics Council of the Department of Medical Sciences (DCM) Universidade de Aveiro Departamento de Ciências Médicas, Portugal
Universidade de Aveiro, Portugal
2018/09/15 - 2022/09/14 Vice-director of BSc in Biomedical Sciences, Department of Medical Sciences Universidade de Aveiro Departamento de Ciências Médicas, Portugal
Universidade de Aveiro, Portugal
2015/01/01 - 2019/12/31 Coordinator of the Depatment of Medical Sciences (DCM) Scientific Program of Summer Academy, UA Universidade de Aveiro, Portugal
Universidade de Aveiro, Portugal
2010/10/01 - 2019/12/31 Co-coordinator of the Neurochemical Dementia Dignostics Unit Universidade de Aveiro, Portugal
Universidade de Aveiro, Portugal
2017/01/01 - 2018/09/15 Head of Ethics Council of the Department of medical Sciences (DCM) Universidade de Aveiro Departamento de Ciências Médicas, Portugal
Universidade de Aveiro, Portugal
2012/02/01 - 2018/09/15 Member of Bachelor's degree in Biomedical Sciences Universidade de Aveiro, Portugal
Universidade de Aveiro, Portugal
2013/02/01 - 2016/12/31 Vice-Coordinator of the Aveiro Node of Portuguese Platform for Bioimaging Universidade de Aveiro, Portugal
Universidade de Aveiro, Portugal
2012/03/01 - 2015/12/31 Coordinator of activities for Forein Affairs (Center for Cell Biology): International Brain WeeK, Summer A cademy and Science Week Universidade de Aveiro, Portugal
Universidade de Aveiro, Portugal
2012/07/01 - 2014/12/31 Member of the Executive Bord of the Research Unit: Center for Cell Biology (secretary) Universidade de Aveiro, Portugal
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2008/05/01 - 2014/12/31 Laboratory of Confocal Microscopy Manager Universidade de Aveiro, Portugal

Others

Category
Host institution 		Employer
2005/03/01 - 2008/04/29 FCT PhD Fellow Fundação para a Ciência e a Tecnologia, Portugal
Universidade de Aveiro, Portugal
2004/01/01 - 2008/04/29 PhD student Universidade de Aveiro, Portugal
Universidade de Aveiro, Portugal
2004/09/01 - 2005/02/28 University of Aveiro PhD Fellow Universidade de Aveiro, Portugal
Universidade de Aveiro, Portugal
2001/03/01 - 2003/06/11 Master Student Universidade de Aveiro, Portugal
Universidade de Aveiro, Portugal
Projects

Grant

Designation Funders
2022/01 - 2024/12 Decifrar o papel da proteína BRI2 na diferenciação neuronal e os mecanismos moleculares subjacentes rumo a uma terapia regenerativa inovadora para a doença de Alzheimer
Provided by PTCRIS: PTDC/BTM-TEC/3792/2021
 Fundação para a Ciência e a Tecnologia, I.P.
2018/06 - 2022/05 Impacto da agregação generalizada de proteínas ao longo da vida em mamíferos e implicações para o desenvolvimento de doenças relacionadas com o envelhecimento.
Provided by PTCRIS: PTDC/BTM-TEC/29843/2017
 Fundação para a Ciência e a Tecnologia, I.P.
2017/02 - 2021/04 Redes sinápticas e abordagens compreensivas de medicina personalizada em doençasneurocomportamentais ao longo da vida
Provided by PTCRIS: SAICTPAC/0010/2015
 Fundação para a Ciência e a Tecnologia, I.P.
2020 - 2020 FENS BRAIN AWARESS WEEK (BAW) PROJECT: 'IMPROVE BRAIN PERFORMANCE'
FENS BAW 2020
Principal investigator
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
 Federation of European Neuroscience Societies
Ongoing
2013/05 - 2015/09 When sperm forget
Provided by PTCRIS: 124922
 Fundação para a Ciência e a Tecnologia, I.P.
2014/01 - 2014/12 FENS BRAIN AWARESS WEEK (BAW) PROJECT: 'Brain Emotions'
FENS-BAW2014
Principal investigator
Universidade de Aveiro, Portugal
 Federation of European Neuroscience Societies
Concluded
2012/01/01 - 2014/01/01 Functional relevance of the novel complex, APP:Fe65:PP1, for Alzheimer's disease
E/ E 120/12
Principal investigator
Universidade de Aveiro, Portugal
 Conselho de Reitores das Universidaddes Portuguesas (CRUP)
Concluded
2010/05 - 2013/09 Mediação por Abeta das respostas bioquímicas subjacentes à histopatologia das placas senis e tranças neurofibrilares na doença de Alzheimer
Provided by PTCRIS: PTDC/QUI-BIQ/101317/2008
 Fundação para a Ciência e a Tecnologia, I.P.
2012/01/01 - 2012/12/31 FENS BRAIN AWARESS WEEK (BAW) PROJECT
BAW2012 PROJECT
Principal investigator
Universidade de Aveiro, Portugal
 Federation of European Neuroscience Societies
Concluded
2008 - 2010 A molecular approach to signal transduction therapeutics
CRUP-Project
Researcher
Universidade de Aveiro, Portugal
 CRUP - Conselho de Reitores das Universidades Portuguesas
Concluded
2005/03 - 2009/04 THE ROLE OF APP CYTOPLASMIC FUNCTIONAL DOMAINS ON PROTEIN TRAFFICKING AND PROCESSING
Provided by PTCRIS: SFRH/BD/17693/2004
 Fundação para a Ciência e a Tecnologia, I.P.
2005/08 - 2008/07 Formação de complexos dependentes de fosforilação, processamento e produção de Abeta da Proteína Precursora da Doença de Alzheimer
Provided by PTCRIS: POCI/BIA-BCM/58469/2004
 Fundação para a Ciência e a Tecnologia, I.P.
2003 - 2005 O processamento e endocitose da Proteína Precursora de Amilóide de Alzheimer na base molecular da Doença de Alzheimer
AstraZeneca
Researcher
Universidade de Aveiro, Portugal
 AstraZeneca Produtos Farmacêuticos Lda
Concluded

Contract

Designation Funders
2021/09/01 - Current Unravelling the molecular mechanisms deregulated in response to LAP1 dysfunction using a proteomic approach: novel insights on human LAP1’s biological functions
EPIC-XS-0000374
Principal investigator
European Proteomics Infrastructure Consortium providing access (EPIC-XS)
Ongoing
2021/04/01 - Current Exploring the intramembrane cleavage of BRI2: proteolytic fragments sequence identification.
EPIC-XS-0000268
Principal investigator
Ongoing
2022/01/01 - 2024/12/31 BRI2 role in neuronal differentiation and the underlying molecular mechanisms: towards an innovative regenerative therapy for Alzheimer’s Disease
PTDC/BTM-TEC/3792/2021
Principal investigator
Universidade de Aveiro Instituto de Biomedicina, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2020/01/01 - 2023/12/31 Projeto da Unidade de Investigação: Instituto de Biomedicina-iBiMED
UID/BIM/04501/2020
Principal investigator
Universidade de Aveiro Instituto de Biomedicina, Portugal
 Fundação para a Ciência e a Tecnologia, I.P.
Ongoing
2020/09/01 - 2022/08/31 Identification of molecular targets for Myotonic Dystrophy type 1 using a proteomic approach
EPIC_XS-0000183
Principal investigator
European Proteomics Infrastructure Consortium providing access (EPIC-XS)
2018/03/01 - 2022/06/01 WISDOM - Impact of wide-spread proteome aggregation through aging in mammals and implications for the development of age-related diseases
PTDC/BTM-TEC/29843/2017
Principal investigator
Universidade de Aveiro Instituto de Biomedicina, Portugal
 Ministério da Ciência Tecnologia e Ensino Superior
Ongoing
2018/06/01 - 2022/05/31 Impact of wide-spread proteome aggregation through aging in mammals and implications for the development of age-related diseases.
PTDC/BTM-TEC/29843/2017
Universidade de Aveiro Instituto de Biomedicina, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Universidade do Minho, Portugal

Universidade de Aveiro, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2020/09/01 - 2021/06/30 Development of a BRI2-based regenerative therapy for Alzheimer´s disease
CENTRO-01-0246-FEDER-000018
Principal investigator
European Regional Development Fund
Ongoing
2018/06/01 - 2021/05/31 GoBack New therapeutics targets for spinal cord regeneration
PTDC/CVT-CVT/32261/2017
Universidade de Aveiro, Portugal

Universidade de Aveiro Instituto de Biomedicina, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2017 - 2021 Synaptic networks and Personalized Medicine Approaches to Understand Neurobehavioural Diseases Across the Lifespan
SAICTPAC/0010/2015
Researcher
Universidade de Aveiro Instituto de Biomedicina, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2017 - 2021 Synaptic networks and Personalized Medicine Approaches to Understand Neurobehavioural Diseases Across the Lifespan
SAICTPAC/0010/2015
 Fundação para a Ciência e a Tecnologia, I.P.
2018/01/01 - 2020/12/31 MEDISIS: Promoção do envolvimento dos atores chave da Região Centro para a transferência de conhecimento e criação de novas parcerias nas áreas da Medicina de Sistemas
CENTRO-01-0246-FEDER-000018
Researcher
European Regional Development Fund
Ongoing
2017/01/01 - 2020/12/31 Protein aggregation across the life span-pAGE
Centro-01-0145-FEDER-000003
Researcher
Universidade de Aveiro Instituto de Biomedicina, Portugal
 Comissão de Coordenação e Desenvolvimento Regional do Centro
Ongoing
2016 - 2019 AD-BLOOD-ASSAY Diagnóstico precoce e preditivo na doença de Alzheimer baseado em sangue
P2020-PTDC/DTP-PIC/5587/2014
Other
Universidade de Aveiro Instituto de Biomedicina, Portugal
 Fundação para a Ciência e a Tecnologia, I.P.
Concluded
2015 - 2019 Projeto da Unidade de Investigação: Instituto de Biomedicina-iBiMED
UID/BIM/04501/2013
UID/BIM/04501/2019
UID/BIM/04501/2019
Researcher
Universidade de Aveiro Instituto de Biomedicina, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2012/06 - 2015/05 BIOMARKAPDua - Biomarkers for Alzheimer's disease and Parkinson's disease, University of Aveiro.
grant.Provided by PTCRIS: 123874
Researcher
Fundação para a Ciência e a Tecnologia
2012/01 - 2014/12 A novel regulatory mechanism of the TGFbeta cascade by the recently described PP1/Tctex1d4 complex
grant.Provided by PTCRIS: 118492
Provided by PTCRIS: 118492
Researcher
Fundação para a Ciência e a Tecnologia

Fundação para a Ciência e a Tecnologia, I.P.
2011/02 - 2014/07 Deciphering neurotrophic signaling pathways mediated by the Alzheimer's Amyloid Precursor Protein, APP
grant.Provided by PTCRIS: 111980
Provided by PTCRIS: 111980
Researcher
Fundação para a Ciência e a Tecnologia

Fundação para a Ciência e a Tecnologia, I.P.
2011 - 2014 New strategies Applied to Neuropathological Disorders
CENTRO-07-ST24-FEDER-002034
Researcher
Universidade de Aveiro, Portugal
 Comissão de Coordenação e Desenvolvimento Regional do Centro
Concluded
2010/05 - 2013/09 Abeta mediated biochemical responses underlying senile plaque and neurofibrillary tangle histopathology in Alzheimer's disease
grant.Provided by PTCRIS: 101317
Post-doc
Fundação para a Ciência e a Tecnologia
2009/03/01 - 2011/06/30 Unravelling the molecular and cellular mechanisms of the novel trimeric complex (APP/FE65/PP1gamma and its functional relevance to Alzheimer's disease
SFRH/BPD/45611/2008
Post-doc Fellow
Universidade de Aveiro, Portugal
 Fundação para a Ciência e a Tecnologia
2007/04 - 2010/09 Clinical Neuroproteomics of Neurodegenerative Diseases
37950
Post-doc Fellow
European Commission
2005/08 - 2009/07 Phosphorylation dependent complex formation, processing and Abeta production of the Alzheimer's Amyloid Precursor protein
grant.Provided by PTCRIS: 58469
Provided by PTCRIS: 58469
Researcher
Fundação para a Ciência e a Tecnologia

Fundação para a Ciência e a Tecnologia, I.P.
2005 - 2008 The role of APP cytoplasmic functional domains on protein trafficking and processing
SFRH/BD/17693/2004
PhD Student Fellow
Universidade de Aveiro, Portugal
 Fundação para a Ciência e a Tecnologia
2004/01 - 2006/12 Abnormal proteins in the pathogenesis of neurodegenerative disorders
503330
Researcher
European Commission
2003/02 - 2006/12 Abeta complex formation: role in Abeta aggregation or clearance.
Provided by PTCRIS: 40682
Research Fellow
Fundação para a Ciência e a Tecnologia
2004/09/01 - 2005/02/28 The role of APP cytoplasmic functional domains on protein trafficking and processing
bolsa da UA
PhD Student Fellow
Universidade de Aveiro, Portugal
 Universidade de Aveiro
Concluded
2001/10 - 2004/09 Early diagnosis of Alzheimer's disease and related dementia
QLK3-CT-2001-02362
Research Fellow
European Commission
2001/03 - 2003/09 CELL SURFACE EXPRESSION AND ENDOCYTOSIS OF THE ALZHEIMER'S AMYLOID PRECURSOR PROTEIN
Provided by PTCRIS: 34349
Master Student Fellow
Fundação para a Ciência e a Tecnologia
Outputs

Publications

Book chapter
  1. Rebelo, Sandra. "Beyond the brain Signaling". In Tissue-Specific Cell Signaling. Springer nature, 2020.
    Published
  2. Pereira, Cátia D.; Martins, Filipa; Marques, Fernanda; Sousa, João Carlos; Rebelo, Sandra. "Beyond Brain Signaling". In Tissue-Specific Cell Signaling, edited by Silva, Joana V.; Freitas, Maria J.; Fardilha, Margarida, 1-32. Springer Cham, 2020.
    Published • 10.1007/978-3-030-44436-5_1
  3. Rebelo, Sandra. "Segundos mensageiros". In eSsencials em: Sinalização celular. Edições Afrontamento, 2015.
    Published
  4. Rebelo, Sandra; Margarida Fardilha; sandra I veira; da Cruz e Silva, Edgar F.; Odete A. B. da Cruz e Silva. "Implementação de métodos activos no processo de ensino/aprendizagem nas Ciências Biomédicas da Universidade de Aveiro". In Docência no Ensino Superior: Partilha de Boas Práticas. UA Editora, 2009.
    Published
  5. Fardilha, M.; Rebelo, S.; Vieira, S.I.; Da Cruz e Silva, O. A.; Da Cruz E Silva, E.F.. "Implementação de métodos activos no processo de ensino/aprendizagem nas CBM da UA". In Docência no Ensino Superior: Partilha de Boas Práticas, edited by Huet, I.; Costa, N.; Tavares, J.; Baptista, A.V.. Editora da UA, 2009.
    Published
Conference abstract
  1. Almeida, Idália; Filipa Martins; Cátia D. Pereira; Brian James Goodfellow; Carla Alexandra Pina da Cruz Nunes; Rebelo, Sandra. Corresponding author: Carla Alexandra Pina da Cruz Nunes. "Optineurin as a potencial target to understand neuronal development and neurodegenerative diseases". Paper presented in Research Summit 2023 - Research Forum of the University of Aveiro, Aveiro, 2023.
    Published
  2. Rebelo, Sandra; Diana Viegas; Pereira, Cátia D.; Martins, Filipa; Mateus, Tiago; da Cruz e Silva, Odete; Herdeiro, Maria Teresa. "Nuclear Envelope Dysfunction in Myotonic Dystrophy Type 1". Paper presented in 17th International Congress on Neuromuscular Diseases (ICNMD 2022), Brussels, 2022.
    Accepted
  3. Rebelo, Sandra; Mateus, Tiago; Adriana Costa; Diana Viegas; Marques, Alda; Herdeiro, Maria Teresa. "Frequently used outcome measures to evaluate muscle strength in patients with Myotonic Dystrophy type 1". Paper presented in 17th International Congress on Neuromuscular Diseases (ICNMD 2022), Brussels, 2022.
    Accepted
  4. Rebelo, S.; Martins, Filipa; Santos, M.; Tenreiro, A. P.; Henriques, A. G.; Oliveira, J.M.; Carvalho, L.P.; et al. "Brain in motion.". Paper presented in FENS Metting, Barcelona, 2012.
    Published
  5. Rebelo, Sandra. "The use of GFP fusion constructs to study the role of APP phosphorylation". Paper presented in Society for neuroscience Conference, New Orleans, 2003.
  6. Henriques, A.G.; Rebelo, Sandra; da Cruz e Silva, E. F.; da Cruz e Silva, O. A. B.. "Cellular signalling and processing of the Alzheimer’s Amyloid Precursor Protein". Paper presented in XII National Meeting of Biochemistry, Póvoa do Varzim, 2000.
    Accepted
Conference paper
  1. Cátia D. Pereira; Guadalupe Espadas; Filipa Martins; Anne T. Bertrand; Laurent Servais; Eduard Sabidó; Odete A. B. da Cruz e Silva; Sandra Rebelo. "New Insights on Signaling Pathways Deregulated in LAP1-Deficient Cells: A Proteomics Study". 2023.
    10.3390/blsf2023021025
  2. Martins, Filipa; Francisco, Stephany; Sousa, Jéssica; Pereira, Cátia D.; Correia, Liliana; Camões, Fátima; Helguero, Luísa; Soares, Ana Raquel; Rebelo, Sandra. "Widespread protein aggregation across the mouse lifespan". 2019.
  3. Martins, Filipa; Francisco, Stephany; Sousa, Jéssica; Pereira, Cátia D.; Correia, Liliana; Camões, Fátima; Soares, Ana Raquel; Rebelo, Sandra. "Evaluation of proteostasis across mammalian lifespan". 2018.
  4. Rebelo, Sandra. "Abnormal phosphorylation of APP-Thr668 induced by Abeta on primary neuronal cultures.". Paper presented in 11th International Conference AD/PD, Florence, March 2013, Florence, 2013.
    Published
  5. Rebelo, Sandra. "APP:Fe65:PP1 tricomplex modulates APP phosphorylation levels". Paper presented in 11th International Conference AD/PD, Florence, March 2013, Florence, 2013.
    Published
  6. Rebelo, Sandra. "Phosphorylation of the Alzheimer’s Amyloid Precursor Protein modulates its Retromer-mediated retrieval from the endosome to the TGN". Paper presented in 10th International Conference AD/PD, 2011, Barcelona, 2011.
    Published
  7. Rebelo, Sandra. "The role of PKCepsilon on APP expression and abeta production". Paper presented in 9th International Conference AD/PD, Prague, 2009.
    Published
  8. Rebelo, Sandra. "PKCalpha Regulates APP vesicular traffic and stimulated sAPP release.". Paper presented in 9th International Conference AD/PD, Prague, 2009.
Conference poster
  1. Martins, Filipa; Cruz, Ana; Sanchez, Jana; Munoz, Javier; Rebelo, Sandra. "Unravelling the molecular mechanisms underlying Myotonic Dystrophy Type 1 using a proteomic approach". Paper presented in IDMC-14 - International Myotonic Dystrophy Consortium Meeting 2024 edition, 2024.
  2. Martins, Filipa; Cruz, Ana; Costa, Adriana; Viegas, Diana; Mateus, Tiago; Rebelo, Sandra. "Unravelling the molecular mechanisms underlying Myotonic Dystrophy Type 1: towards the development of novel and effective treatments". Paper presented in Myotonic Dystrophy Young Investigator Meeting, 2023.
  3. Martins, Filipa; Chen, Gefei; Zao, Hongjing; Nilsson, Per; Tambaro, Simone; Rebelo, Sandra. "Pro-neurogenic therapeutic approaches based on BRI2 modulation". Paper presented in 11th World Congress of Neuroscience IBRO 2023, 2023.
  4. Vassal, Mariana; Martins, Filipa; Savchuk, Ruslana; Camões, Fátima; Serrano, Julia; Martínez-Murillo, Ricardo; Rebelo, Sandra. "Unravelling BRI2 expression and processing during neuronal differentiation". Paper presented in 11th World Congress of Neuroscience IBRO 2023, 2023.
  5. Vassal, Mariana; Martins, Filipa; Savchuk, Ruslana; Chen, Gefei; Zhao, Hongjing; Nilsson, Per; Tambaro, Simone; Rebelo, Sandra. "BRI2 Protein: A Promising Therapeutic Target for Innovative Alzheimer's Disease Treatment". Paper presented in Encotnro Ciência 2023, 2023.
  6. Vassal, Mariana; Martins, Filipa; Savchuk, Ruslana; Chen, Gefei; Hongjing, Zhao; Nilsson, Per; Tambaro, Simone; Rebelo, Sandra. Corresponding author: Martins, Filipa. "Exploring the Potential of BRI2 Protein as a Novel Therapeutic Avenue for Alzheimer's Disease". Paper presented in Workshop on Novel Diagnostic Tools for Alzheimer´s Disease, 2023.
  7. Almeida, Idália; Filipa Martins; Cátia D. Pereira; Brian James Goodfellow; Carla Alexandra Pina da Cruz Nunes; Rebelo, Sandra. Corresponding author: Rebelo, Sandra. "Optineurin: A Target to Decipher Neuronal Development and Neurodegenerative Mechanisms". Paper presented in Encontro Ciência Viva, 2023.
  8. Vassal, Mariana; Martins, Filipa; Savchuk, Ruslana; Chen, Gefei; Hongjing, Zhao; Nilsson, Per; Tambaro, Simone; Rebelo, Sandra. "Novel perspectives on neuronal differentiation: insights from BRI2 protein". Paper presented in VI iBiMED symposium: From fundamental research to clinical practice, 2023.
  9. Almeida, Idália; Martins, Filipa; Pereira, Cátia D.; Goodfellow, Brian J.; Nunes, Alexandra; Rebelo, Sandra. "The role of optineurin in neuronal development and differentiation". Paper presented in VI Post-Graduate Symposium in Biomedicine, Universidade de Aveiro, Aveiro, Portugal, 2023.
  10. Cruz, Ana Catarina; Martins, Filipa; Sanchez, Jana; Munoz, Javier; Rebelo, Sandra. "Identification of molecular targets for Myotonic Dystrophy Type 1 using a proteomic approach". Paper presented in Master´s Day at DCM 2023 - 2nd edition, 2023.
  11. Tambaro, Simone; Chen, Gefei; Zhao, Hongjing; Nilsson, Per; Martins, Filipa; Rebelo, Sandra. "A novel therapeutic approach for Alzheimer´s disease based on BRI2 protein". Paper presented in AD/PD 2023 International Conference on Alzheimer's and Parkinson's Diseases and related neurological disorders, 2023.
  12. Pereira, Cátia D.; Espadas, Guadalupe; Martins, Filipa; Bertrand, Anne T.; Servais, Laurent; Sabidó, Eduard; da Cruz e Silva, Odete A. B.; Rebelo, Sandra. "New Insights on Signaling Pathways Deregulated in LAP1-Deficient Cells: A Proteomics Study". Paper presented in Cells, Cells and Nothing but Cells: Discoveries, Challenges and Directions - Part of the International Online Conference on Cells series, online event, 2023.
  13. Pereira, Cátia D.; Espadas, Guadalupe; Martins, Filipa; Bertrand, Anne T.; Servais, Laurent; Sabidó, Eduard; da Cruz e Silva, Odete A. B.; Rebelo, Sandra. "Unravelling the molecular mechanisms deregulated in LAP1-associated diseases using a proteomics approach". Paper presented in 26th Annual Meeting of the Portuguese Society of Human Genetics (SPGH - Sociedade Portuguesa de Genética Humana), Coimbra, Portugal, 2022.
  14. Vassal, Mariana; Pereira, Cátia Daniela; Martins, Filipa; Silva, Vera LM; Silva, Artur MS; Senos, Ana; Costa, Elisabete; Pereira, Maria de Lourdes; Rebelo, Sandra. "Chalcone supplementation as a strategy to mitigate the reproductive toxicity of ZnO nanoparticles". Paper presented in CICECO Jornadas 2022 – Hand in Hand in Science, 2022.
  15. Vassal, Mariana; Rebelo, Sandra; Maria de Lourdes Pereira. "Adverse effects of metal oxide nanoparticles on male germ cells". Paper presented in WebRePRO I Reproductive Science & Fertility Virtual Summit, 2021.
  16. Pinho, Ana Rita; Martins, Filipa; Costa, Elisabete; Senos, Ana; da Cruz e Silva, Odete AB; Pereira, Maria de Lourdes; Rebelo, Sandra. "Are ZnO-NPs harmless to spermatogenesis? Focusing cytoskeleton and nucleoskeleton dynamics in spermatogonia cells". Paper presented in Andrology 2020 - 12th International/11th European/ 32nd German Congress of Andrology, 2020.
  17. Pereira, Cátia D.; Martins, Filipa; Sorrentino, G.; da Cruz e Silva, O. A. B.; Rebelo, S.. "LAP1:TRF2 interaction during the DNA damage response.". Paper presented in X Meeting in Signal Transduction (SINAL 2019), 2019.
  18. Pereira, Cátia D.; Marafona, Ana M.; Martins, Filipa; Sorrentino, G.; da Cruz e Silva, O. A. B.; Rebelo, S.. "The role of the novel LAP1:TRF2 complex in DNA damage response.". Paper presented in V Post-graduate Symposium on Biomedicine, University of Aveiro, 2019.
  19. Rebelo, S.; Martins, Filipa; Pereira, Cátia D.; da Cruz e Silva, O. A. B.. "BRI2 is a novel player in neuritogenesis.". Paper presented in 14th International Conference on Alzheimer’s & Parkinson’s Diseases (ADPD), 2019.
  20. Pinho, Ana Rita; Martins, Filipa; Costa, E.; Senos, A.; Rebelo, S.; Pereira, ML. "The effects of ZnO Nanoparticles in Spermatogonia Cells.". Paper presented in V Post-graduate Symposium on Biomedicine, 2019.
  21. Martins, Filipa; Francisco, S.; Nobre, A.; Santa, C.; Camões, F.; Manadas, B.; Rebelo, S.; Soares, A. R.. "Characterization of wide-spread proteome aggregation through aging in mammals". Paper presented in EMBO Proteostasis, Ericeira, 2019, 2019.
  22. Martins, Filipa; Francisco, Stephany; Sousa, J; Pereira, Cátia D; Correia, Liliana; Camões, Fátima; Helguero, Luísa; Soares, Ana R; Rebelo, Sandra. "Evaluation of proteostasis across mammalian lifepsan". Paper presented in IV Postgraduate Symposium on Biomedicine, 2018.
  23. Henriques, Ana Gabriela; Rebelo, S.; Blennow, K.; Zetterberg, H.; da Cruz e Silva, O.A.B.. "Participation of the Neuroscience and Signalling Laboratory from Aveiro in The Alzheimer´s Association QC Program". Paper presented in 2nd meeting of the CSF society, 2018.
  24. Martins, Filipa; Francisco, S.; Sousa, J.; Pereira, Cátia D.; Correia, L.; Camoes, F.; Helguero, L.; Soares, A. R.; Rebelo, S.. "Evaluation of proteostasis across mammalian lifespan.". Paper presented in iBiMED’s IV Post-Graduate Symposium in Biomedicine, 2018.
  25. Martins, Filipa; Pereira, Cátia D.; da Cruz e Silva, O. A.B.; Rebelo, S.. "BRI2 is a key player in neuritogenesis.". Paper presented in III iBiMED Postgrad symposium on Biomedicine, 2017.
  26. Costa, M.; Alves, S.; Rebelo, S.; Henriques, A. G.; da Cruz e Silva, O. A. B.. "Alzheimer’s Amyloid Precursor Protein: structural and functional relationships. Postgrad symposium on Biomedicine.". Paper presented in Postgrad symposium on Biomedicine, 2017.
  27. Gonçalves, Sandra F. ; Goncalves, Gil; Vila, Mercedes; Hortiguela, Maria J. ; Rebelo, Sandra; Loureiro, Susana. "Eco-friendly profile of pegylated nanographene oxide synthesized for medical application". Paper presented in SETAC Europe 27th Annual Meeting, 2017.
  28. Costa, M.; Alves, S.; Rebelo, S.; Henriques, A. G.; da Cruz e Silva, O. A. B.. "Structural functional relationships of the Alzheimer’s Amyloid Precursor Protein.". Paper presented in XV Meeting of the Portuguese Society of Neurosciences, 2017.
  29. Gonçalves, S. F.; Vila, M.; Hortiguela, M. J.; Rebelo, S.; Loureiro, S.. "Eco-friendly profile of pegylated nanographene oxide synthetized for medical application.". Paper presented in SETAC 2017, 2017.
  30. Martins, Filipa; Rebelo, S.; Pereira, Cátia D.. "BRI2 is a novel player in neuronal differentiation.". Paper presented in Research Day UA 2017, 2017.
  31. Martins, Filipa; Pereira, Cátia D.; da Cruz e Silva, O. A. B.; Rebelo, S.. "BRI2 is a key player in neuritogenesis.". Paper presented in XV Meeting of the Portuguese Society of Neurosciences, 2017.
  32. Soares, A. R.; Francisco, S.; Tomé, D.; Rebelo, S.; Santos, M.. "Study of proteome imbalances during aging in mice.". Paper presented in Internacional Meeting Unfolded proteins: from basic to bedside., 2016.
  33. Martins, Filipa; Serrano, J. B.; Rebelo, S.; da Cruz e Silva, O.A. B.. "Phosphoregulation of BRI2 is crucial for neuritogenesis promotion.". Paper presented in II iBiMED postgrad symposium, 2016.
  34. Serrano, J. B.; van Pelt, A. M. M.; da Cruz e Silva, O. A. B.; Rebelo, S.. "TorsinA, a new player in Spermatogenesis.". Paper presented in Microscopy society meeting, 2016.
  35. Martins, Filipa; Rebelo, Sandra; Santos, Mariana; Cotrim, Cândida Z.; da Cruz e Silva, Odete A. B.; da Cruz e Silva, Edgar F.. "A novel interaction for PP1 with BRI family members". Paper presented in Research Day UA 2014, 2014.
  36. Rebelo, S.; Martins, Filipa; Santos, M.; Cotrim, C. Z.; da Cruz e Silva, E. F.; da Cruz e Silva, O. A. B.. "A novel interaction for Protein Phosphatase 1 with BRI family members.". Paper presented in Research Day UA 2014, 2014.
  37. Oliveira, J.M.; Henriques, A. G.; Martins, Filipa; Rebelo, S.; da Cruz e Silva, O. A. B.. "Abeta role in APP and Tau phosphorylation: relevance to Alzheimer´s disease.". Paper presented in Research Day UA 2014, 2014.
  38. Fardilha, M.; Amaro, A.; Rebelo, S.; Rocha, N.. "Licenciatura em Ciências Biomédicas: ensino/aprendizagem baseada em problemas.". Paper presented in Teaching Day, 2014.
  39. Oliveira, J.; Henriques, Ana Gabriela; Martins, F.; Rebelo, S.; da Cruz e Silva, O.A.B.. "APP Thr668 phosphorylation correlates with Abeta exposure". Paper presented in SINAL 2013, 7th National Meeting on Cell Signaling, 2013.
  40. Oliveira, J. M.; Henriques, A. G.; Martins, Filipa; Rebelo, S.; da Cruz e Silva, O. A. B.. "APP Thr668 phosphorylation correlates with Aß exposure.". Paper presented in 7th National Meeting on Cell Signaling, University of Aveiro, 2013.
  41. Tenreiro, S.; Rebelo, S.; Martins, Filipa; Santos, M.; Coelho, E. D.; Alves de Matos, A. P.; da Cruz e Silva, O. A. B.. "Isolation of synaptosomal-enriched fractions using Sucrose and Percoll based methodologies.". Paper presented in 7th National Meeting on Cell Signaling, 2013.
  42. Rebelo, S.; Domingues, S, S.; Santos, M.; Esteves, S. L. C.; Vieira, S. I.; Vintém, A. P.; Wu, Wenjuan; Da Cruz E Silva, E.F.; da Cruz e Silva, O. A.B.. "APP:Fe65:PP1 tricomplex modulates APP phosphorylation levels.". Paper presented in 7th National Meeting on Cell Signaling, 2013.
  43. Rebelo, S.; Sacramento, S.; da Cruz e Silva, O.A. B.. "Differentiation of olfactory mucosa stem cells into neuron-like cells.". Paper presented in Microscopy in Research 2013, 2013.
  44. Santos, M.; Rebelo, S.; Dauer, William T.; da Cruz e Silva, E. F.; da Cruz E Silva, A. B. O.. "Effect of dystonia-associated torsinA mutant in cytoskeleton dynamics.". Paper presented in Microscopy in Research 2013, 2013.
  45. Rebelo, S.; Tenreiro, A. P.; Martins, Filipa; Santos, M.; Coelho, E. D.; Alves de Matos, A. P.; da Cruz e Silva, O. A. B.. "Comparison of Sucrose and Percoll based methodologies for isolation of synaptosomal-enriched fractions.". Paper presented in Microscopy at the Frontiers of Science, 2013.
  46. Rebelo, S.; Domingues, S. S.; Santos, M.; Fardilha, M.; Esteves, S. L. C.; Vintém, A. P.; Wu, Wenjuam; da Cruz e Silva, E. F.; da Cruz e Silva, O. A. B.. "Identification of a novel trimeric complex (APP:Fe65:PP1) that is relevant for Alzheimer’s Disease.". Paper presented in Research Day, 2013.
  47. Rebelo, S.; Domingues, S. S.; Santos, M.; Fardilha, M.; Esteves, S. L. C.; Vieira, S. I.; Vintém, A. P.; et al. "APP:Fe65:PP1 tricomplex modulates APP phosphorylation levels.". Paper presented in 11th Internacional Conference on Alzheimer’s and Parkinson Diseases (AD/PD 2013)., 2013.
  48. Oliveira, J. M.; Henriques, A. G.; Rebelo, S.; Martins, Filipa; da Cruz e Silva, O. A. B.. "Abnormal phosphorylation of APP-Thr668 induced by Abeta on primary neuronal cultures.". Paper presented in 11th International Conference on Alzheimer’s & Parkinson’s Diseases (AD/PD 2013), 2013.
  49. Fardilha, M.; Amaro, A.; Rebelo, S.; Rocha, N.. "Sessões Tutoriais – Ensino/Aprendizagem para o Futuro. Inovação Pedagógica na Universidade de Aveiro". Paper presented in Teaching Day-2º edição, Aveiro, Portugal, 2013.
  50. Santos, M.; Rebelo, S.; da Cruz e Silva, O. A. B.; da Cruz e Silva, E. F.. "Determining the relevance of the novel PP1/LAP1/TorsinA complex for DYT1 dystonia.". Paper presented in Research day, 2012.
  51. de Oliveira, Joana Machado; Henriques, Ana Gabriela; Martins, Filipa; Rebelo, Sandra; da Cruz e Silva, Odete A. B.. "Abeta mediated effects on APP phosphorylation". Paper presented in 6th National Meeting on Cell Signaling, 2012.
  52. Oliveira, J.; Henriques, Ana Gabriela; Martins, F.; Rebelo, S.; da Cruz e Silva, O.A.B.. "Aß mediated effects on APP phosphorylation.". Paper presented in Sinal 2012, 2012.
  53. Santos, M.; Rebelo, S.; Van Kleeff, P.; Fardilha, M.; da Cruz e Silva, O. A. B.; da Cruz e Silva, E. F.. "LAP1B is a novel PP1 binding protein localized in the nuclear membrane.". Paper presented in 6th ANNUAL Meeting on Cell Signalling., 2012.
  54. Martins, Filipa; Rebelo, S.; Oliveira, J. M.; Henriques, A. G.; da Cruz e Silva, O. A. B.. "Abeta differentially modulates tau phosphorylation.". Paper presented in 6th National Meeting on Cell Signaling, 2012.
  55. Santos, M.; Rebelo, S.; Van Kleeff, P.; Fardilha, M.; da Cruz e Silva, O. A. B.; da Cruz e Silva, E. F.. "LAP1B interacts with PP1 through its nucleoplasmic domain.". Paper presented in EMBO workshop: ‘Advances in protein-protein interaction analysis and modulation´, 2012.
  56. Rebelo, S.; Santos, M.; Van Kleeff, P.; Fardilha, M.; da Cruz e Silva, O. A. B.; da Cruz e Silva, E. F.. "Characterization of the novel LAP1B complexes and their relevance to DYT1 dystonia.". Paper presented in 5th International Dystonia Symposium, 2011.
  57. Rebelo, S.; Santos, M.; da Cruz e Silva, O.A. B.; da Cruz e Silva, E. F.. "Subcellular distribution of Protein Phosphatase 1 isoforms in mammalian cells.". Paper presented in SINAL 2011 – 5th National Meeting on Signal Transduction, 2011.
  58. Vieira, S. I.; Rebelo, S.; Esselmann, H.; Wiltfang, J.; Lah, J.; Lane, R.; Small, S. A; et al. "Phosphorylation of the alzheimer’s amyloid precursor protein modulates its retromer-mediated retrieval from the endosome to the TGN.". Paper presented in AD/PD 2011, 2011.
  59. Rebelo, S.; Henriques, A. G.; da Cruz e Silva, E. F.; da Cruz e Silva, O.A. B.. "Biomarkers in Alzheimer’s disease.". Paper presented in Research Day, 2011.
  60. Santos, M.; Rebelo, S.; da Cruz e Silva, O.A. B.; da Cruz e Silva, E. F.. "Subcellular distribution of Protein Phosphatase 1 isoforms in mammalian cells.". Paper presented in Microscopy at the Frontiers of Science, Second joint Congress of the Portuguese and Spanish Microscopy Societies, 2011.
  61. Vieira, S. I.; Rocha, J. F.; Rebelo, S.. "APP phosphorylation at S655 positively regulates its nuclear signalling – implications to neurite outgrowth.". Paper presented in EMBO meeting, 2011.
  62. Rebelo, S.; Vieira, S. I.; da Cruz e Silva, E. F.; da Cruz e Silva, O. A. B.. "Phosphorylation at s655 determines the cellular fate of the alzheimer’s amyloid precursor protein.". Paper presented in SINAL 2010 – 4th National Meeting on Signal Transduction., 2010.
  63. Fardilha, M.; Esteves, S. L. C.; Domingues, S. S.; Rebelo, S.; Korrodi-Gregório, L.; da Cruz e Silva, E. F.. "Characterization of the protein phosphatase 1 interactome from human testis.". Paper presented in . SINAL 2010 – 4th National Meeting on Signal Transduction., 2010.
  64. Rebelo, S.; Monteiro, S. R.; da Cruz E Silva, A. B. O.; Lopes da Silva, J. A.. "Effect of Molecular weight and degrre of Branching of galactomannans on heat induced gelation of soy protein at neutral pH.". Paper presented in . Food Colloids, 2010.
  65. Rebelo, S.; Vieira, S. I.; Gandy, S.; Greengard, P.; da Cruz e Silva, E. F.; da Cruz e Silva, O. A.B.. "The role of PKCepsilon on APP expression and abeta production.". Paper presented in AD/PD 2009, 2009.
  66. Vieura, S. I.; Rebelo, S.; Gandy, S.; Greengard, P.; da Cruz e Silva, E. F.; da Cruz e Silva, O. A.B.. "PKCalpha Regulates APP vesicular traffic and stimulated sAPP release.". Paper presented in AD/PD 2009, 2009.
  67. Vieira, S. I.; Rebelo, S.; Esselmann, H.; Wiltfang, J.; da Cruz e Silva, E. F.; da Cruz e Silva, O. A.B.. "S655 phosphorylation regulates APP retrograde transport, enhancing APP half-life and decreasing app lysosomal targeting.". Paper presented in 33rd FEBS Congress, 2008.
  68. Henriques, Ana Gabriela; Vieira, S.I.; Rebelo, S.; Crespo-López, M.E.; Oliveira, M.; da Cruz e Silva, E.F.; da Cruz e Silva, O. A. B.. "Abeta leads to intracellular sAPP accumulation at cytoskeleton associated vesicular-like densities". Paper presented in 33rd FEBS Congress, 2008.
    10.1055/s-0038-1677242
  69. Vieira, S. I.; Rebelo, S.; da Cruz e Silva, E. F.. "Neuronal phospho-S655 APP is preferentially targeted to neuritic terminals.". Paper presented in 10th Meeting of Portuguese Neuroscience Society, 2007.
  70. Henriques, A.G.; Vieira, S. I.; Rebelo, S.; Domingues, S. S.; Da Cruz E Silva, E.F.; da Cruz e Silva, O. A. B.. "Different Amyloid Precursor Protein isoforms have distinct fates.". Paper presented in 10th Meeting of Portuguese Neuroscience Society, 2007.
  71. Rebelo, S.; Vieira, S. I.; Esselmann H.; Wiltfang, J.; da Cruz e Silva, E. F.; da Cruz e Silva, O. A. B.. "Tyrosine 687 phosphorylation affects the intracellular location and procesing of the Alzheimer’s amyloid precursor protein.". Paper presented in 10th Meeting of Portuguese Neuroscience Society, 2007.
  72. Rebelo, S.; Vieira, S. I.; Esselmann H.; Wiltfang, J.; da Cruz e Silva, E. F.; da Cruz e Silva, O. A. B.. "The role of the NPTY domain on APP subcellular distribution and Abeta production.". Paper presented in 8TH INTERNATIONAL CONFERENCE ON ALZHEIMER'S & PARKINSON'S DISEASES: AD/PD 2007, 2007.
  73. Henriques, A.G.; Vieira, S. I.; Rebelo, S.; Domingues, S. S.; da Cruz e Silva, E. F.; da Cruz e Silva, O. A. B.. "APP isoform-specific differences in metabolism.". Paper presented in 8TH INTERNATIONAL CONFERENCE ON ALZHEIMER'S & PARKINSON'S DISEASES: AD/PD 2007, 2007.
  74. Vieira, S. I.; Rebelo, S.; da Cruz e Silva, E. F.; da Cruz e Silva, O. A. B.. "Ser655 phosphorylation on APP determines the protein’s intracellular fate.". Paper presented in ICAD - 10th International Conference of Alzheimer’s Disease, 2006.
  75. Rebelo, S.; Vieira, S. I.; da Cruz e Silva, E. F.; da Cruz e Silva, O. A. B.. "The effect of the phosphorylation sate of Tyr687 on APP endocytosis.". Paper presented in 7th International Conference AD/PD 2005, 2005.
  76. Vieira, S. I.; Rebelo, S.; da Cruz e Silva, E. F.; da Cruz e Silva, O. A. B.. "The effect of the phosphorylation sate of Ser655 on APP endocytosis.". Paper presented in 7th International Conference AD/PD 2005, 2005.
  77. Vitém, A.; Henriques, A.; Wu, W.; Fardilha, M.; Sousa, C.; Amador, F.; Domingues, S.; et al. "Parallel universes come together: phosphorylation and Alzheimer’s disease". Paper presented in 4th Post-Graduation Symposium, Aveiro, Portugal, 2005.
  78. Rebelo, Sandra; Vieira, S. I.; da Cruz e Silva, E. F.; da Cruz e Silva, O. A. B.. "The importance of Y687 on APP intracellular trafficking.". Paper presented in 4th Forum of European Neuroscience, 2004.
  79. Vieira, S. I.; Rebelo, Sandra; da Cruz e Silva, E. F.; da Cruz e Silva, O. A. B.. "Phosphorylation dependent sorting of the Alzheimer’s Amyloid Precursor protein". Paper presented in 4th Forum of European Neuroscience, 2004.
  80. da Cruz e Silva, O. A. B.; Rebelo, S.; Vieira, S. I.; da Cruz e Silva, E. F.. "The role of protein phosphorylation in the control of APP processing.". Paper presented in 9Th International Conference on Alzheimer’s disease and related disorders, 2004.
  81. Rebelo, Sandra; Guerra e Paz, S. V.; da Cruz e Silva, E. F.. "Intracellular protein trafficking: a model system to study protein processing.". Paper presented in II Post-Graduation Symposium in Biosciences, 2003.
  82. Rebelo, Sandra; Guerra e Paz, S. V.; da Cruz e Silva, E. F.; and da Cruz e Silva, O. A. B.. "The role of Y687 in APP trafficking and processing". Paper presented in 8ª Meeting of Portuguese Neuroscience Society, 2003.
  83. da Cruz e Silva, O. A. B.; Guerra e Paz, S. V.; Rebelo, Sandra; da Cruz e Silva, E. F.. "The use of GFP fusion constructs to study the role of APP phosphorylation.". Paper presented in Society for Neuroscience 33rd Annual Meeting, 2003.
  84. Rebelo, Sandra; da Cruz e Silva, E. F.; and da Cruz e Silva, O. A. B.. "The role of endocytosis in APP metabolism and Abeta production.". Paper presented in I Post-Graduation Symposium in Biosciences, 2002.
  85. Guerrra e Paz, S. V.; Rebelo, Sandra; da Cruz e Silva, E. F.; and da Cruz e Silva, O. A. B.. "The use of APP-GFP fusions to study APP processing and trafficking". Paper presented in XIII National Meeting of Biochemistry, 2002.
  86. Henriques, A.G.; Rebelo, Sandra; da Cruz e Silva, E. F.; da Cruz e Silva, O. A. B.. "Effects of different signalling mechanisms on the expression and processing of APP.". Paper presented in Portuguese Biochemical Society Meeting, 2000.
Journal article
  1. Cláudia Martins; Idália Almeida; Sandra Rebelo; Sandra Magalhães; Alexandra Nunes. "Age-Related Fourier-Transform Infrared Spectroscopic Changes in Protein Conformation in an Aging Model of Human Dermal Fibroblasts". Spectroscopy Journal (2023): https://doi.org/10.3390/spectroscj1010004.
    10.3390/spectroscj1010004
  2. Martins, Claudia; Magalhães, Sandra; Almeida, Idália; Neto, Vanessa; Rebelo, Sandra; Nunes, Alexandra. "Metabolomics to Study Human Aging: A Review". Current Molecular Medicine 23 (2023): http://dx.doi.org/10.2174/1566524023666230407123727.
    Published • 10.2174/1566524023666230407123727
  3. Adriana Costa; Ana C. Cruz; Filipa Martins; Sandra Rebelo. "Protein Phosphorylation Alterations in Myotonic Dystrophy Type 1: A Systematic Review". International Journal of Molecular Sciences (2023): https://doi.org/10.3390/ijms24043091.
    10.3390/ijms24043091
  4. Dhvani H. Kuntawala; Filipa Martins; Rui Vitorino; Sandra Rebelo. "Automatic Text-Mining Approach to Identify Molecular Target Candidates Associated with Metabolic Processes for Myotonic Dystrophy Type 1". International Journal of Environmental Research and Public Health (2023): https://doi.org/10.3390/ijerph20032283.
    10.3390/ijerph20032283
  5. Mariana Vassal; Cátia D. Pereira; Filipa Martins; Vera L. M. Silva; Artur M. S. Silva; Ana M. R. Senos; Maria Elisabete V. Costa; Maria de Lourdes Pereira; Sandra Rebelo. "Different Strategies to Attenuate the Toxic Effects of Zinc Oxide Nanoparticles on Spermatogonia Cells". Nanomaterials (2022): https://doi.org/10.3390/nano12203561.
    10.3390/nano12203561
  6. Sandra Magalhães; Idália Almeida; Cátia D. Pereira; Sandra Rebelo; Brian J. Goodfellow; Alexandra Nunes. "The Long-Term Culture of Human Fibroblasts Reveals a Spectroscopic Signature of Senescence". International Journal of Molecular Sciences 23 10 (2022): 5830-5830. https://doi.org/10.3390/ijms23105830.
    10.3390/ijms23105830
  7. Mateus, Tiago; Costa, Adriana; Viegas, Diana; Marques, Alda; Herdeiro, Maria Teresa; Rebelo, Sandra. "Outcome measures frequently used to assess muscle strength in patients with myotonic dystrophy type 1: a systematic review". Neuromuscular Disorders 32 2 (2022): 99-115. http://dx.doi.org/10.1016/j.nmd.2021.09.014.
    10.1016/j.nmd.2021.09.014
  8. Viegas, Diana; Pereira, Cátia D.; Martins, Filipa; Mateus, Tiago; da Cruz e Silva, Odete A. B.; Herdeiro, Maria Teresa; Rebelo, Sandra. "Nuclear Envelope Alterations in Myotonic Dystrophy Type 1 Patient-Derived Fibroblasts". International Journal of Molecular Sciences 23 1 (2022): 522. http://dx.doi.org/10.3390/ijms23010522.
    10.3390/ijms23010522
  9. Sandra Magalhães; Idália Almeida; Filipa Martins; Fátima Camões; Ana R. Soares; Brian J. Goodfellow; Sandra Rebelo; Alexandra Nunes. "FTIR Spectroscopy as a Tool to Study Age-Related Changes in Cardiac and Skeletal Muscle of Female C57BL/6J Mice". Molecules (2021): https://doi.org/10.3390/molecules26216410.
    10.3390/molecules26216410
  10. Magalhães, Sandra; Almeida, Idália; Martins, Filipa; Camões, Fátima; Soares, Ana R; Goodfellow, Brian J; Rebelo, Sandra; Nunes, Alexandra. "FTIR Spectroscopy as A Tool to Study Age-Related Changes in Cardiac and Skeletal C57bl/6j Female Mice Muscle". Molecules (2021):
    Published
  11. Martins, Filipa; Santos, Isabela; da Cruz e Silva, Odete A. B.; Tambaro, Simone; Rebelo, Sandra. "The role of the integral type II transmembrane protein BRI2 in health and disease". Cellular and Molecular Life Sciences 78 21-22 (2021): 6807-6822. http://dx.doi.org/10.1007/s00018-021-03932-5.
    10.1007/s00018-021-03932-5
  12. Vassal, Mariana; Rebelo, Sandra; Pereira, Maria de Lourdes. "Metal Oxide Nanoparticles: Evidence of Adverse Effects on the Male Reproductive System". International Journal of Molecular Sciences 22 15 (2021): 8061. http://dx.doi.org/10.3390/ijms22158061.
    10.3390/ijms22158061
  13. "Cardiac, skeletal and respiratory methods and outcome measures of choice to evaluate muscle strength of patients with Myotonic Dystrophy Type 1: A review". Journal of Statistics on Health Decision (JSHD) 3 1 (2021): 18-25.
    Published
  14. "Development of a comprehensive clinical report form for assessing patients with Myotonic Dystrophy type 1". Statistics on Health Decision Making: Public Health 3 1 (2021): 76-79.
    Accepted
  15. Rebelo, S.. "Two novel molecular approaches towards deciphering Myotonic Dystrophy type 1". Journal of Neuromuscular diseases (2021):
    In press
  16. Mateus, Tiago; Almeida, Idália; Costa, Adriana; Viegas, Diana; Magalhães, Sandra; Martins, Filipa; Herdeiro, Maria Teresa; et al. "Fourier-Transform Infrared Spectroscopy as a Discriminatory Tool for Myotonic Dystrophy Type 1 Metabolism: A Pilot Study". International Journal of Environmental Research and Public Health 18 7 (2021): 3800. http://dx.doi.org/10.3390/ijerph18073800.
    10.3390/ijerph18073800
  17. Tiago Mateus; Filipa Martins; Alexandra Nunes; Maria Teresa Herdeiro; Sandra Rebelo. "Metabolic Alterations in Myotonic Dystrophy Type 1 and Their Correlation with Lipin". International Journal of Environmental Research and Public Health 18 4 (2021): 1794-1794. https://doi.org/10.3390/ijerph18041794.
    Open access • 10.3390/ijerph18041794
  18. Cátia D. Pereira; Filipa Martins; Mariana Santos; Thorsten Müeller; Odete A. B. da Cruz e Silva; Sandra Rebelo. "Nuclear Accumulation of LAP1:TRF2 Complex during DNA Damage Response Uncovers a Novel Role for LAP1". Cells 9 8 (2020): 1804-1804. https://doi.org/10.3390/cells9081804.
    Open access • 10.3390/cells9081804
  19. Martins, Filipa; Sousa, Jéssica; Pereira, Cátia D.; da Cruz e Silva, Odete A. B.; Rebelo, Sandra. "Nuclear envelope dysfunction and its contribution to the aging process". Aging Cell (2020): e13143. http://dx.doi.org/10.1111/acel.13143.
    Open access • 10.1111/acel.13143
  20. Ana Rita Pinho; Sandra Rebelo; Maria de Lourdes Pereira. "The Impact of Zinc Oxide Nanoparticles on Male (In)Fertility". Materials (2020): https://www.mdpi.com/1996-1944/13/4/849.
    Open access • 10.3390/ma13040849
  21. Pinho, A. R.; Martins, Filipa; Costa, E.; Senos, A.; da Cruz e Silva, O. A. B.; Pereira, M. l.; Rebelo, S.. "In Vitro Cytotoxicity Effects of Zinc Oxide Nanoparticles on Spermatogonia Cells". Cells 9 5 (2020):
    Open access • Published • 10.3390/cells9051081
  22. Cátia D. Pereira; Joana B. Serrano; Filipa Martins; Odete A. B. da Cruz e Silva; Sandra Rebelo. "Nuclear envelope dynamics during mammalian spermatogenesis: new insights on male fertility". Biological Reviews 94 4 (2019): 1195-1219. https://doi.org/10.1111/brv.12498.
    10.1111/brv.12498
  23. Susana Loureiro; Sandra Filipe Gonçalves; Gil Gonçalves; Maria Jesús Hortiguela; Sandra Rebelo; Marta Carmona Ferro; Mercedes Vila. "Eco-friendly profile of pegylated nano-graphene oxide at different levels of an aquatic trophic chain". Ecotoxicology and Environmental Safety 162 (2018): 192-200. https://doi.org/10.1016%2Fj.ecoenv.2018.06.078.
    10.1016/j.ecoenv.2018.06.078
  24. Joana B. Serrano; Filipa Martins; Cátia D. Pereira; Ans M. M. van Pelt; Odete A. B. da Cruz e Silva; Sandra Rebelo. "TorsinA Is Functionally Associated with Spermatogenesis". Microscopy and Microanalysis (2018): 1-8. https://doi.org/10.1017%2Fs1431927618015179.
    10.1017/s1431927618015179
  25. Filipa Martins; Ana M. Marafona; Cátia D. Pereira; Thorsten Müller; Christina Loosse; Katharina Kolbe; Odete A. B. da Cruz e Silva; Sandra Rebelo. "Identification and characterization of the BRI2 interactome in the brain". Scientific Reports 8 1 (2018): https://doi.org/10.1038%2Fs41598-018-21453-3.
    Open access • 10.1038/s41598-018-21453-3
  26. Rebelo, Sandra. "BRI2 Processing and Its Neuritogenic Role Are Modulated by Protein Phosphatase 1 Complexing.". Journal of cellular biochemistry (2017): http://europepmc.org/abstract/med/28176357.
    10.1002/jcb.25925
  27. Rebelo, Sandra. "Descriptive Analysis of LAP1 Distribution and That of Associated Proteins throughout Spermatogenesis.". Membranes (2017): http://europepmc.org/abstract/med/28387711.
    10.3390/membranes7020022
  28. Tenreiro, P.; Rebelo, S.; Martins, F.; Santos, M.; Coelho, E. D.; Almeida, M.; de Matos, A. P. Alves; da Cruz e Silva, O. A. B.. "Comparison of simple sucrose and percoll based methodologies for synaptosome enrichment". Analytical Biochemistry 517 (2017): 1-8. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000390181700001&KeyUID=WOS:000390181700001.
    10.1016/j.ab.2016.10.015
  29. Cátia D. Pereira; Filipa Martins; Jens Wiltfang; Odete A.B. da Cruz e Silva; Sandra Rebelo. "ABC Transporters Are Key Players in Alzheimer’s Disease". Journal of Alzheimer's Disease 61 2 (2017): 463-485. https://doi.org/10.3233%2Fjad-170639.
    10.3233/jad-170639
  30. Martins, Filipa; Rebelo, Sandra; Santos, Mariana; Cotrim, Candida Zita; da Cruz e Silva, Edgar F.; da Cruz e Silva, Odete A. B.. "BRI2 and BRI3 are functionally distinct phosphoproteins". Cellular Signalling 28 1 (2016): 130-144. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000366882700015&KeyUID=WOS:000366882700015.
    10.1016/j.cellsig.2015.10.012
  31. Serrano, Joana B.; da Cruz e Silva, Odete A. B.; Rebelo, Sandra. "Lamina Associated Polypeptide 1 (LAP1) Interactome and Its Functional Features". Membranes 6 1 (2016): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000373724900011&KeyUID=WOS:000373724900011.
    10.3390/membranes6010008
  32. Santos, M.; Rebelo, S.; da Cruz e Silva, E. F.; da Cruz e Silva, O. A. B.. "DYT1 dystonia-associated mutant affects cytoskeletal dynamics". Microscopy and Microanalysis 21 S6 (2015): 26-27. http://dx.doi.org/10.1017/s1431927614013804.
    10.1017/s1431927614013804
  33. Sacramento, S.; Rebelo, S.; da Cruz e Silva, O. A. B.. "Differentiation of olfactory mucosa stem cells into neuron-like cells.". Microsc. and Microanal. 21 (2015): 28-29.
    10.1017/S1431927614013816
  34. Santos, M.; Rebelo, S.; da Cruz e Silva, E. F.; da Cruz e Silva, O. A. B.. "DYT1 dystonia-associated mutant affects cytoskeleton dynamics.". Microsc. and Microanal. 21 (2015): 26-27..
    Doi:10.1017/S1431927614013804 
  35. Rebelo, Sandra; Santos, Mariana; Martins, Filipa; da Cruz e Silva, Edgar F.; da Cruz e Silva, Odete A. B.. "Protein phosphatase 1 is a key player in nuclear events". Cellular Signalling 27 12 (2015): 2589-2598. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000367486400027&KeyUID=WOS:000367486400027.
    10.1016/j.cellsig.2015.08.007
  36. Rebelo, Sandra; da Cruz e Silva, Edgar F.; da Cruz e Silva, Odete A. B.. "Genetic mutations strengthen functional association of LAP1 with DYT1 dystonia and muscular dystrophy". Mutation Research-Reviews in Mutation Research 766 (2015): 42-47. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000367407400004&KeyUID=WOS:000367407400004.
    10.1016/j.mrrev.2015.07.004
  37. Oliveira, Joana M.; Henriques, Ana Gabriela; Martins, Filipa; Rebelo, Sandra; da Cruz e Silva, Odete A. B.. "Amyloid-beta Modulates Both A beta PP and Tau Phosphorylation". Journal of Alzheimers Disease 45 2 (2015): 495-507. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000351583900016&KeyUID=WOS:000351583900016.
    10.3233/JAD-142664
  38. Santos M; Costa P; Martins F; da Cruz E Silva EF; da Cruz E Silva OA; Rebelo S. "LAP1 is a crucial protein for the maintenance of the nuclear envelope structure and cell cycle progression.". (2014): http://europepmc.org/abstract/med/25323962.
    10.1007/s11010-014-2241-x
  39. Domingues SC; Konietzko U; Henriques AG; Rebelo S; Fardilha M; Nishitani H; Nitsch RM; da Cruz E Silva EF; da Cruz E Silva OA. "RanBP9 modulates AICD localization and transcriptional activity via direct interaction with Tip60.". (2014): http://europepmc.org/abstract/med/25024339.
    10.3233/JAD-132495
  40. Margarida Fardilha; João Figueiredo; Margarita Espona-Fiedler; Juliana Felgueiras; Luís Korrodi-Gregório; Sara L. C. Esteves; Sandra Rebelo; et al. "Phosphoprotein Phosphatase 1 Isoforms Alpha and Gamma Respond Differently to Prodigiosin Treatment and Present Alternative Kinase Targets in Melanoma Cells". Journal of Biophysical Chemistry 5 (2014): 67-77..
    10.4236/jbpc.2014.52008
  41. Santos M; Domingues SC; Costa P; Muller T; Galozzi S; Marcus K; da Cruz E Silva EF; da Cruz E Silva OA; Rebelo S. "Identification of a Novel Human LAP1 Isoform That Is Regulated by Protein Phosphorylation.". (2014): http://europepmc.org/abstract/med/25461922.
    10.1371/journal.pone.0113732
  42. Sandra Rebelo; Sara C. Domingues; Mariana Santos; Margarida Fardilha; Sara L. C. Esteves; Sandra Isabel Vieira; Ana Paula B. Vintém; et al. "Identification of a Novel Complex AßPP:Fe65:PP1 that Regulates AßPP Thr668 Phosphorylation Levels". Journal of Alzheimer's Disease 35 4 (2013): 761-775. https://doi.org/10.3233%2Fjad-130095.
    10.3233/jad-130095
  43. Monteiro, Sonia R.; Rebelo, Sandra; da Cruz e Silva, Odete A. B.; Lopes-da-Silva, Jose A.. "The influence of galactomannans with different amount of galactose side chains on the gelation of soy proteins at neutral pH". Food Hydrocolloids 33 2 (2013): 349-360. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000320614500022&KeyUID=WOS:000320614500022.
    10.1016/j.foodhyd.2013.04.012
  44. Santos, Mariana; Rebelo, Sandra; Van Kleeff, Paula J. M.; Kim, Connie E.; Dauer, William T.; Fardilha, Margarida; da Cruz e Silva, Odete A.; da Cruz e Silva, Edgar F.. "The Nuclear Envelope Protein, LAP1B, Is a Novel Protein Phosphatase 1 Substrate". Plos One 8 10 (2013): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000325501300095&KeyUID=WOS:000325501300095.
    10.1371/journal.pone.0076788
  45. Fardilha, Margarida; Ferreira, Monica; Pelech, Steven; Vieira, Sandra; Rebelo, Sandra; Korrodi-Gregorio, Luis; Sousa, Mario; et al. ""OMICS" of Human Sperm: Profiling Protein Phosphatases". Omics-a Journal of Integrative Biology 17 9 (2013): 460-472. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000323820700002&KeyUID=WOS:000323820700002.
    10.1089/omi.2012.0119
  46. Santos, M.; Rebelo, S.; da Cruz e Silva, O. A. B.; da Cruz e Silva, E. F.. "Immunolocalization of PPP1C Isoforms in SH-SY5Y Cells during the Cell Cycle". Microscopy and Microanalysis 18 (2012): 41-42. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000309744500021&KeyUID=WOS:000309744500021.
    10.1017/S143192761201286X
  47. Fardilha, Margarida; Esteves, Sara L. C.; Korrodi-Gregorio, Luis; Vintem, Ana Paula; Domingues, Sara C.; Rebelo, Sandra; Morrice, Nick; et al. "Identification of the human testis protein phosphatase 1 interactome". Biochemical Pharmacology 82 10 (2011): 1403-1415. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000296414400016&KeyUID=WOS:000296414400016.
    10.1016/j.bcp.2011.02.018
  48. Vieira, Sandra I.; Rebelo, Sandra; Esselmann, Hermann; Wiltfang, Jens; Lah, James; Lane, Rachel; Small, Scott A.; et al. "Retrieval of the Alzheimer's amyloid precursor protein from the endosome to the TGN is S655 phosphorylation state-dependent and retromer-mediated". Molecular Neurodegeneration 5 (2010): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000283537500001&KeyUID=WOS:000283537500001.
    10.1186/1750-1326-5-40
  49. da Cruz e Silva, Odete A. B.; Rebelo, Sandra; Vieira, Sandra I.; Gandy, Sam; da Cruz e Silva, Edgar F.; Greengard, Paul. "Enhanced generation of Alzheimer's amyloid-beta following chronic exposure to phorbol ester correlates with differential effects on alpha and epsilon isozymes of protein kinase C". Journal of Neurochemistry 108 2 (2009): 319-330. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000261620000001&KeyUID=WOS:000261620000001.
    10.1111/j.1471-4159.2008.05770.x
  50. Vieira, Sandra Isabel; Rebelo, Sandra; Domingues, Sara Catarina; da Cruz e Silva, Edgar F.; da Cruz e Silva, Odete A. B.. "S655 phosphorylation enhances APP secretory traffic". Molecular and Cellular Biochemistry 328 1-2 (2009): 145-154. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000267592600018&KeyUID=WOS:000267592600018.
    10.1007/s11010-009-0084-7
  51. Rebelo, Sandra; Vieira, Sandra Isabel; da Cruz e Silva, Edgar F.; da Cruz e Silva, Odete A. B.. "Monitoring "De Novo" APP Synthesis by Taking Advantage of the Reversible Effect of Cycloheximide". American Journal of Alzheimers Disease and Other Dementias 23 6 (2008): 602-608. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000262025700011&KeyUID=WOS:000262025700011.
    10.1177/1533317508323572
  52. Ana Gabriela Henriques; Sandra Isabel Vieira; Sandra Rebelo; Sara C.T.S. Domingues; Edgar F. da Cruz e Silva; Odete A.B. da Cruz e Silva. "Isoform Specific Amyloid-ß Protein Precursor Metabolism". Journal of Alzheimer's Disease 11 1 (2007): 85-95. https://doi.org/10.3233%2Fjad-2007-11112.
    10.3233/jad-2007-11112
  53. Rebelo, Sandra; Vieira, Sandra Isabel; Esselmarm, Hermann; Wiltfang, Jens; da Cruz e Silva, Edgar F.; da Cruz e Silva, Odete A. B.. "Tyr(687) dependent APP endocytosis and Abeta production". Journal of Molecular Neuroscience 32 1 (2007): 1-8. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000248159600001&KeyUID=WOS:000248159600001.
    10.1007/s12031-007-0001-z
  54. Rebelo, Sandra; Vieira, Sandra Isabel; Esselmann, Hermann; Wiltfang, Jens; da Cruz e Silva, Edgar F.; da Cruz e Silva, Odete A. B.. "Tyrosine 687 phosphorylated Alzheimer's amyloid precursor protein is retained intracellularly and exhibits decreased turnover rate". Neurodegenerative Diseases 4 2-3 (2007): 78-87. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000248747000002&KeyUID=WOS:000248747000002.
    10.1159/000101831
  55. Sandra I. Vieira; Sandra Rebelo; Edgar F. da Cruz e Silva; Odete A.B. da Cruz e Silva. "Ser655 phosphorylation on APP determines the protein's intracellular fate". Alzheimer's & Dementia 2 3 (2006): S222-S222. https://doi.org/10.1016%2Fj.jalz.2006.05.803.
    10.1016/j.jalz.2006.05.803
  56. Sandra Rebelo; Sara S. Domingues; Sandra I. Vieira; Hermann Esselman; Jens Wiltfang; Edgar F. Cruz e Silva; Odete A. da Cruz e Silva. "The phosphorylation state of Tyr687 on APP contributes to protein-protein interactions and Abeta production". Alzheimer's & Dementia 2 3 (2006): S56-S56. https://doi.org/10.1016%2Fj.jalz.2006.05.203.
    10.1016/j.jalz.2006.05.203
  57. Rebelo, S.; Domingues, S. S.; Vieira, S.; Esselmann, H.; Wiltfang, J.; da Cruz e Silva, E. F.; da Cruz e Silva, O. A. B.. "The phosphorylation state of Tyr687 on APP contributes to protein-protein interactions and Abeta production. ". Alzheimer´s and Dementia  2 (2006): S56-S56.
    10.1016/j.jalz.2006.05.203, ISSN: 1552-5260
  58. Ana Gabriela S. Henriques; Sara Santos; Sandra Rebelo; Sandra Vieira; Edgar F. da Cruz e Silva; Odete A.B. da Cruz e Silva. "Isoform specific responses of the Alzheimer's amyloid precursor protein". Neurobiology of Aging 25 (2004): S38-S39. https://doi.org/10.1016%2Fs0197-4580%2804%2980127-1.
    10.1016/s0197-4580(04)80127-1
  59. Odete A.B. da Cruz e Silva; Sandra Rebelo; Sandra Vieira; Edgar F. da Cruz e Silva. "The role of protein phosphorylation in the control of APP processing". Neurobiology of Aging 25 (2004): S176-S176. https://doi.org/10.1016%2Fs0197-4580%2804%2980596-7.
    10.1016/s0197-4580(04)80596-7
  60. Da Cruz E Silva, O.A.B.; Fardilha, M.; Henriques, A.G.; Rebelo, S.; Vieira, S.; Da Cruz E Silva, E.F.; Odete A. B. da Cruz e Silva; et al. "Signal transduction therapeutics: Relevance for Alzheimer's disease". Journal of Molecular Neuroscience 23 1-2 (2004): 123-142. http://www.scopus.com/inward/record.url?eid=2-s2.0-4344704079&partnerID=MN8TOARS.
    10.1385/JMN:23:1-2:123
  61. da Cruz e Silva, Odete A. B.; Vieira, Sandra Isabel; Rebelo, Sandra; da Cruz e Silva, Edgar F.. "A Model System to Study Intracellular Trafficking and Processing of the Alzheimer's Amyloid Precursor Protein". Neurodegenerative Diseases 1 4-5 (2004): 196-204. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000208226100007&KeyUID=WOS:000208226100007.
    10.1159/000080986
  62. Rebelo, S; Henriques, AG; Silva, EFDCE; Silva, OABDCE. "Effect of cell density on intracellular levels of the Alzheimer's amyloid precursor protein". Journal of Neuroscience Research 76 3 (2004): 406-414. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000221183100015&KeyUID=WOS:000221183100015.
    10.1002/jnr.20091
Newsletter article
  1. Mariana Santos; Domingues, Sara Catarina; Patrícia Costa; Thorsten Müller; Galozzi S; Edgar F. da Cruz e Silva; Markus, k; da Cruz e Silva, Odete A. B.; Rebelo, Sandra. "Identification of a novel human nuclear envelope LAP1 isoform, LAP1C", Research@ua, 2014
  2. Mariana Santos; Rebelo, Sandra; Van Kleeff, Paula J. M.; Kim, Connie E.; Dauer, William T.; Fardilha, Margarida; da Cruz e Silva, Odete A. B.; da Cruz e Silva, E. F.. "The nuclear envelope protein, LAP1B, is a novel Protein Phosphatase 1", research@ua, 2013
  3. Sandra I. Vieira; Rebelo, Sandra; Esselmann, Hermann; Jens Wiltfang; Lah, James; Lane, Rachel; Gandy, Sam; Odete A.B. da Cruz e Silva. "Retrieval of the alzheimer’s amyloid precursor protein from the endosome to the TGN occurs via the retromer and is dependent on protein phosphorylation", Research@ua, 2011
Newspaper article
  1. Mariana Santos; Rebelo, Sandra; da Cruz e Silva, Odete A. B.. "Dia Mundial das Doenças Raras", Universidade de Aveiro, 2012
Thesis / Dissertation
  1. Rebelo, Sandra. "The role of the NPTY functional domain on APP trafficking and processing". PhD, Universidade de Aveiro, 2008. http://hdl.handle.net/10773/946.
  2. Rebelo, Sandra. "Effect of cell density on the expression of the Alzheimer’s Amyloid precursor protein". Master, Universidade de Aveiro Departamento de Biologia, 2003. http://hdl.handle.net/10773/21665.

Other

Other output
  1. Torsin 1A Interacting Protein 1. 2017. Joana B. Serrano; Filipa Martins; Ana M. Marafona; Odete A. B. da Cruz e Silva; Sandra Rebelo. https://doi.org/10.1007%2F978-3-319-67199-4_101846.
    10.1007/978-3-319-67199-4_101846
  2. Protein Phosphatase 1 (PP1). 2017. Filipa Martins; Joana B. Serrano; Ana M. Marafona; Odete A. B. da Cruz e Silva; Sandra Rebelo. https://doi.org/10.1007%2F978-3-319-67199-4_101767.
    10.1007/978-3-319-67199-4_101767
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2020/10/18 Uma abordagem Clínica, Epidemiológica e Molecular na Distrofia Miotónica tipo 1 (DM1). 1º Open Day | MEDISIS: apresentação de projetos de investigação clínicos.
(Aveiro, Portugal)
2019/11/29 Widespread protein aggregation across the mouse lifepsan. pAGE workshop meeting
Universidade de Aveiro (Aveiro, Portugal)
2019/10 How Safe are ZnO Nanoparticles on Male Reproductive Health? International Symposium on Medicinal Resources of Countries along One Belt and One Road
Guangxi University of Chinese Medicine (China)
2019/10 The safety of ZnO Nanoparticles on Male Reproductive Health. -5th Hunan Innovative International Conference on Biomedicine and Chinese Medicine Changsha, Faculty of Medicine
(China)
2019/07 O cérebro e novas terapias celulares para doenças neurológicas Palestra no âmbito da Academia de verão 2017 no programa intitulado ‘Engenharia Biomédica e a qualidade de vida humana’
(Aveiro, Portugal)
2018/11/20 BRI2 processing ans its neuritogenic role are modulated by Protein Phosphatase 1 complexing. Workshop_ Signalling Evening
Universidade de Aveiro, Departamento de Ciências Médicas
2018/10/25 Rodent Animal Facility of iBiMED/UA Animal Model of Disease. Workshop de Experimentação Animal.
(Aveiro, Portugal)
2018/09 Protein aggregation profiles across the mouse lifepsan. Research summit 2018
(Aveiro, Portugal)
2018/07/13 Widespread protein aggregation across the mouse lifepsan. pAGE Project workshop meeting,
(Aveiro, Portugal)
2018/07/06 Dinâmica da Membrana Nuclear na Saúde e na Doença Dia do iBiMED no CHVNG/E
(Aveiro, Portugal)
2018/07 ‘O cérebro e novas terapias celulares para doenças neurológicas’ Palestra no âmbito da Academia de verão 2018 no programa intitulado ‘Engenharia Biomédica e a qualidade de vida humana’
(Aveiro, Portugal)
2018 The novel LAP1:TRF2 complex is associated to DNA damage response. iBiMED’s IV Post-Graduate Symposium in Biomedicine
(Aveiro, Portugal)
2017/07/17 O cérebro e novas terapias celulares para as doenças neurológicas. Academia de verão 2017 programa entitulado 'Engenharia Biomédica e a qualidade de vida humana'
departamento de Física, Universidade de Aveiro (Aveiro, Portugal)
2017/03/25 Rodent Animal Facility iBiMED/UA. Animal model of Disease. Workshop de Experimentação Animal
Departamento de ciências Médicas, Universidade de Aveiro (Aveiro, Portugal)
2016/07/26 Organização do novo currículo da Licenciatura em Ciências Biomédicas (PBL-Problem Based Learning). Dia do PBL @UA
(Aveiro, Portugal)
2015/04/20 LAP1 and related nuclear-envelope associated diseases. iBiMED Seminar Series 2015
Medical Sciences Department, University of Aveiro
2014/07/07 Protein Phosphorylation in Health and Disease. Curso de Stem Cells @ Pasteur Insitute
Pasteur Institute (Paris, France)
2014 Phosphorylation dependent Alzheimer's Amyloid Precursor Protein (APP) trafficking. Simpósio de Microscopia Electrónica.
Insituto Egas Moniz
2013/11/06 Biomarcadores da Doença de Alzheimer numa coorte portuguesa-complementaridade com informação clínica, imagiológica e genética. Congresso de Neurologia
(Faro, Portugal)
2012 Licenciatura em Ciências Biomédicas: ensino/aprendizagem baseada em problemas. Workshop: Práticas de Qualidade no Ensino e Aprendizagem na Universidade de Aveiro
(Aveiro, Portugal)
2010/05/21 Phosphorylation at S655 determines cellular afte of the Alzheimer's amyloid Preursor Protein. SINAl 2010- 4th National Meeting on Signal Transduction
Algarve University (Faro, Portugal)
2008/03/07 Doença de Alzheimer: estado Actual. Conferência na Casa Museu Egas Moniz, Semana Insternacional do Cérebro
Casa Museu Egas Moniz (Estarreja, Portugal)
2008 Molecular advances in APP biology. 22ª Reunião do Grupo de Estudos de Envelhecimento Cerebral e Demências
Grupo de Estudos de Envelhecimento Cerebral e Demências (Luso, Portugal)
2006/07/10 The phosphorylation state of Try687 on APP contributes to protein-protein interactions and Abeta production. ICAD-10th International Conference od Alzheimer's disease.
Madrid (Madrid, Spain)
2006/05/04 The role of Tyr 687 phosphorylation in APP processing. INSERM Conference
Insitutet de Pharmacologie Moléculaire at Celulaire (Nice, France)
2006/03/22 Phosphorylation of the APP intracellular domain affects its trafficking and processing. APOPIS thematic workshop
(St Moritz, Switzerland)
2006 The phosphorylation state of Try687 on APP contributes to protein-protein interactions and Abeta production. ICAD - 10th International Conference of Alzheimer’s Disease
Alzheimer's association (Madrid, Spain)
2005/10/20 Direct APP phosphorylation determines its intracellular fate. Fourth International Congress on Vascular Demnetia
Universidade do Porto (Porto, Portugal)
2005/09/08 The use of the Yeast Two-Hybrid System to identify specific interactions. APOPIS metting.
(Brussels, Belgium)
2005/09 The use of the Yeast Two-Hybrid System to identify specific interactions.
APOPIS Meeting (Brussels, Belgium)
2005/06 O peptídeo Abeta e a Doença de Alzheimer. 19ª Reunião do Grupo de Estudos de Envelhecimento Cerebral e Demências
Grupo de Estudos de Envelhecimento Cerebral e Demências (Tomar, Portugal)
2005/05 Parallel Universes come together: Phosphorylation and Alzeimer’s disease IV Post-Graduation Symposium in Biosciences
(Aveiro, Portugal)
2004 Isoform specific responses of the Alzheimer’s Amyloid Precursor Protein. 9Th International Conference on Alzheimer’s disease and related disorders
azheimer's association (Philadelphia, United States)
2004 Glutamatergic signalling is involved in the processing of APP. III Post-Graduation Symposium in Biosciences
(Aveiro, Portugal)
2004 Phosphorylation dependent APP processing XIV Congresso Nacional de Bioquímica
Universidade do Algarve (Faro, Portugal)
2003/06/13 Alzheimer’s Amyloid Precursor Protein Phosphorylation: Driving it through traffic? 8ª Meeting of Portuguese Neuroscience Society
Portuguese Neuroscience Society (Curia, Portugal)
2003/06/04 The importance of Y687 on APP intracellular trafficking and processing 18ª Reunião do Grupo de Estudos de Envelhecimento Cerebral e Demências
Grupo de Estudos de Envelhecimento Cerebral e Demências (Óbidos, Portugal)
2003 Intracellular protein trafficking: a model system to study protein processing. II Post-graduation Symposium in Biosciences
Departamento de Biologia, Universidade de Aveiro
2003 Alzheimer’s Amyloid Precursor Protein Phosphorylation: Driving it through traffic? 8ª Meeting of Portuguese Neuroscience Society
Portuguese Neuroscience Society (Curoa, Portugal)
2001/07 Effects of different signalling mechanisms on the expression and processing of APP. Lisboa, Julho. FEBS Meeting 2001
FEBS (Lisbon, Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2021/06/01 - 2025/05/31 Identifying Novel Molecular Targets for Myotonic Dystrophy type 1
Supervisor
 Biomedicina (PhD)
Universidade de Aveiro, Portugal
2021/09/01 - 2022/12/15 Metabolome of cells: a tool for aging research
Co-supervisor
 Mestrado em Biomedicina Molecular
Universidade de Aveiro, Portugal
2021/09/15 - 2022/12/14 Relatório de estágio em tarefas regulamentares e de monitorização na W4research
Supervisor
 Mestrado em gestão de Investigação clínica (Master)
Universidade Nova de Lisboa Comprehensive Health Research Centre, Portugal
2022/01/01 - 2022/12 Unravelling BRI2 role in neuronal differentiation
Supervisor
 Biomedicina Molecular (Master)
Universidade de Aveiro, Portugal
2018/11/01 - 2022/10/31 Unravelling the molecular mechanisms of LAP1-associated pathologies using patient fibroblasts ans iPSCs
Supervisor of Cátia Daniela Isaías Pereira
 Dotoral programe in Biomedicine (PhD)
Universidade de Aveiro, Portugal
2020/09/01 - 2021/12/17 Different strategies to attenuate the reproductive toxicity of ZnO Nanoparticles
Co-supervisor
 Biologia Molecular e Celular (Master)
Universidade de Aveiro, Portugal
2020/09/01 - 2021/12/13 Identification of new phopshorylation regulated targets for Myotonic Dystrophy type 1.
Supervisor of Nuno Regêncio
 Molecular Biomedicine (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2019 - 2021/12/10 SYNTHESIS AND CYTOTOXICITY STUDIES OF PYRAZOLES TO COUNTERACT DNA DAMAGE AND NEURODEGENERATION INDUCED BY OXIDATIVE STRESS
Co-supervisor
 Bioquímica
Universidade de Aveiro, Portugal
2019 - 2021/02/24 Nuclear envelope dysfunctions observed in patients with Myotonic Dystrophy type 1
Supervisor of Diana Ferreira Viegas
 Biomedicina Molecular (Master)
Universidade de Aveiro, Portugal
2019 - 2021/02/18 Establishment of skin-derived fibroblast cell lines for the study of protein phosphorylation in Myotonic Dystrophy type 1.
Supervisor
 Biomedicina Molecular (Master)
Universidade de Aveiro, Portugal
2019 - 2021/02/12 Study of the metabolome and muscle strength measures for the characterization of patients with Myotonic Dystrophy type 1
Supervisor of Tiago Duarte Cordeiro Mateus
 Biologia Molecular e Celular (Master)
Universidade de Aveiro, Portugal
2020/09/01 - 2021 Neuronal differentation mediated by BRI2: towards innovative regenerative therapies
Supervisor of Maria Isabela Santos
 Molecular Biomedicine
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2018 - 2019/12/12 The effects of ZnO nanoparticles on male germ cells.
Co-supervisor of Ana Rita Arede Pinho
 Biomedicina Molecular (Master)
Universidade de Aveiro, Portugal
2018 - 2019/12/05 Characterization of the nuclear envelope alterations in Myotonic Dystrophy Type 1
Supervisor of Ana Cláudio Miquelino Basílio
 Biomedicina Molecular (Master)
Universidade de Aveiro, Portugal
2017 - 2018 The role of the nuclear envelope proteins during normal aging
Supervisor of Jéssica Fabiana Sousa
 Biomedicina Molecular (Master)
Universidade de Aveiro, Portugal
2016/09/01 - 2017/06/15 The role of the novel LAP1:TRF2 complex is in DNA damage and cell cycle
Supervisor
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2012 - 2017/04/17 Functional Characterization of novel BRI2 and BRI3 complexes
Supervisor
 Biomedicina (PhD)
Universidade de Aveiro, Portugal
2016 - 2017 Transcriptional and redox changes in Huntington's disease human stem cells
Supervisor of Nuno André Reis Piedade
 Biomedicina Molecular (Master)
Universidade de Aveiro, Portugal
2015 - 2016 The novel LAP1:TRF2 complex is associated to DNA damage
Supervisor
 Biomedicina Molecular (Master)
Universidade de Aveiro, Portugal
2014 - 2015 The role of LAP1 in spermatogenesis
Supervisor of Joana Margarida Bispo Serrano
 Molecular Biomedicine (Master)
Universidade de Aveiro, Portugal
2014 - 2015 Caracterização Genética e Epigenética do carcinoma da laringe
Co-supervisor of Vanessa Alexandra Marques
 Molecular Biomedicine (Master)
Universidade de Aveiro, Portugal
2010/01/01 - 2014/05/30 Caracterization of novel LAP1 complexes and their relevance for DYT1 dystonia’
Supervisor of Santos Moreda Graça
Doutoramento em Ciências Biomédicas (PhD)
Universidade de Aveiro, Portugal
2013 - 2014 Preparing PP1 related molecular tools (shRNAS and fluorescent fused vectors)
Supervisor
 Molecular Biomedicine (Master)
Universidade de Aveiro, Portugal
2012 - 2013 Knocking-down LAP1 using the short hairpin RNA strategy
Supervisor
 Molecular Biomedicine (Master)
Universidade de Aveiro, Portugal
2012 - 2013 Stem cell-based model system to study neuropathologies
Supervisor
 Molecular Biomedicine (Master)
Universidade de Aveiro, Portugal
2011 - 2012 The use of synaptossomes for the study of APP and Tau phosphorylation
Supervisor
 Molecular Biomedicine (Master)
Universidade de Aveiro, Portugal
2011 - 2012 Establishing stem cell-based model systems to study neuropathologies
Co-supervisor
 Molecular Biomedicine (Master)
Universidade de Aveiro, Portugal
2010/09 - 2011/07 Synaptosomal Signal Transduction in Alzheimer's disease
Supervisor
 Molecular Biomedicine (Master)
Universidade de Aveiro, Portugal
2010 - 2011 Abeta dependent tau phosphorylation
Co-supervisor
 Molecular Biomedicine (Master)
Universidade de Aveiro, Portugal
2010 - 2011 Targeted Gene Theraphy to Non-Small Cell Lung Cancer: Cetuximab linked chitosan carrying hec1 silencin siRNA
Co-supervisor
 Biologia Molecular e Celular (Master)
Universidade de Aveiro, Portugal
2008/09 - 2009/12 LAP1B as a novel PP1 regulator
Co-supervisor
 Mestrado em Biologia Molecular e Celular (Master)
Universidade de Aveiro, Portugal
2006 - 2009 Identification of neuronal proteins that interact with PP1y2
Co-supervisor
 Mestrado em Métodos Biomoleculares avançados (Master)
Universidade de Aveiro, Portugal

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2021/02/24 Nuclear envelope dysfunctions observed in patients with Myotonic Dystrophy type 1
Supervisor
 Diana Viegas (Master)
Universidade de Aveiro, Portugal
2021/02/18 Establishment of skin-derived fibroblast cell lines for the study of protein phosphorylation in Myotonic Dystrophy type 1
Supervisor
 ADRIANA EMÍLIA AMARAL COSTA (Master)
Universidade de Aveiro, Portugal
2021/02/12 Study of the metabolome and muscle strength measures for the characterization of patients with type 1 myotonic dystrophy
Supervisor
 Tiago Duarte Cordeiro Mateus (Master)
Universidade de Aveiro, Portugal
2021/02/03 Phosphorylation mediated events in biomarker discovery for Alzheimer's disease.
(Thesis) Arguer
 Joana Machado de Oliveira (PhD)
Universidade de Aveiro, Portugal
2020/10/15 Regucalcin as one of the guardians of the male reproductive function
(Thesis) Main arguer
 Ana Manuela dos Santos Silva (PhD)
Universidade da Beira Interior, Portugal
2019/12/16 Dissection of striato-nigrostriatal Circuits
(Thesis) Main arguer
 Sílvia Cristina Fernandes Moreira (Master)
Universidade de Aveiro, Portugal
2019/12/12 The Effects of ZnO nanoparticles on male germ cells
Supervisor
 Ana Rita Arede Pinho (Master)
Universidade de Aveiro, Portugal
2019/12/05 The role of mistranslation in the acquisition of antifungal resistance
President of the jury
 Matilde de Almeida Figueiredo (Master)
Universidade de Aveiro, Portugal
2019/12/05 Characterization of the nuclear envelope alterations in Myotonic Dystrophy type 1
Supervisor
 Ana Cláudia Miquelino Basílio (Master)
Universidade de Aveiro, Portugal
2019/11/01 Bmp4 pathway alterations in Lmna-/- myoblasts.
(Thesis) Arguer
 Alexandre Janin (PhD)
Université Catholique de Lyon, France
2019/06/12 Técnicas de Laboratório em Análises Clínicas
(Thesis) Arguer
 Beatriz Duarte Santos (Other)
Universidade de Aveiro, Portugal
2018/12/18 Characterizing of the nuclear envelope alterations during ageing
Supervisor
 Jéssica Fabiana Moreira de Sousa (Master)
Universidade de Aveiro, Portugal
2018 Establishing Gao as a plasticity marker and neuroregenerative protein.
(Thesis) Arguer
 Roberto Dias (PhD)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2017/12/13 Exosomes as tools for biomarker discovery
President of the jury
 João Andé Fernades Jesus (Master)
Universidade de Aveiro, Portugal
2017/07/21 Exosomes as tools for biomarker discovery
President of the jury
 Tânia Cristina Martins (Master)
Universidade de Aveiro, Portugal
2017/04/27 Functional Characterization of novel BRI2 and BRI3 complexes
Supervisor
 Filipa Sá Martins (PhD)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2016/12/21 Testing a dementia risk group for polymorphisms in inflammation-related genes
President of the jury
 Sandra Daniela Silva Guedes (Master)
Universidade de Aveiro, Portugal
2016/12/20 The role of N-glycan in the structure and function of the C. elegans nervous system
(Thesis) Main arguer
 Ana Cristina Costa Veloso (Master)
Universidade do Minho Escola de Medicina, Portugal
2016/12/13 The novel LAP1:TRF2 complex is associated to DNA damage
Supervisor
 Ana Marlene Neto Marafona (Master)
Universidade de Aveiro, Portugal
2015/12/17 LAP1 role in spermatogenesis
Supervisor
 Joana Bispo Serrano (Master)
Universidade de Aveiro, Portugal
2015/12/09 Amyloid Precursor Protein Thr668 phophodependent complexes
President of the jury
 Sérgio Paulo Soares Reguengo (Master)
Universidade de Aveiro, Portugal
2015 Altered regulatory response of Rab7a and Rab9 in MM1 and VV2 subtype of Creutzfeldt- Jacob disease
(Thesis) Main arguer
 Susana Margarida da Silva Correia (Master)
Universidade de Aveiro, Portugal
2014/12/16 Produce and test PP1 Molecular Biology tools
Supervisor
 Margarida Costa (Master)
Universidade de Aveiro, Portugal
2014/05/30 Caracterization of novel LAP1 complexes and their relevance for DYT1 dystonia
Supervisor
 Mariana Santos Moreda Graça (PhD)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2013/12/11 Establishing model systems from olfactory mucosa stem cells
Supervisor
 Sónia Raquel Capela Sacramento (Master)
Universidade de Aveiro, Portugal
2013/07/04 Mesenchymal Stem Cells Differentiation into Oligodendroglial-like Lineage: Complementary roles of soluble factors, extracellular matrix and mechanotransduction.
(Thesis) Main arguer
 Catatina Domingues (Other)
Biocant Associação de Transferência de Tecnologia, Portugal
2013/06/13 Knocking-down LAP1 using the short hairpin RNA strategy
Supervisor
 Patrícia Costa (Master)
Universidade de Aveiro, Portugal
2012/12/19 Estudo do gene PROC em individuos com defeciência de proteína C
(Thesis) Main arguer
 Joana Rita Silva (Master)
Universidade de Aveiro, Portugal
2012/12/12 Establishing stem cell-based model systems to study neuropathologies
Supervisor
 Sofia Carvalho (Master)
Universidade de Aveiro, Portugal
2012/07/12 The use of synaptossomes for the study of APP and Tau phosphorylation
Supervisor
 Patrícia Tenreiro (Master)
Universidade de Aveiro, Portugal
2011/12/20 Targeted Gene Therapy to Non-Small Cell Lung Cancer: Cetuximab linked chitosan carrying hec1 silencing siRNA
Supervisor
 Susana Silva (Master)
Universidade de Aveiro, Portugal
2011/07/01 Synaptosomal Signal Transduction in Alzheimer's Disease
Supervisor
 Edgar Duarte de Jesus Valente Marques Coelho (Master)
Universidade de Aveiro, Portugal
2011/06/29 ABETA dependent tau phosphorylation
Supervisor
 Filipa Sá Martins (Master)
Universidade de Aveiro, Portugal
2010/12/17 A FE65 é uma proteína predominante no interactoma da APP
(Thesis) Main arguer
 Adérito Batista Capelo (Master)
Universidade de Aveiro, Portugal
2009/12/12 LAP1B as a novel PP1 regulator
Supervisor
 Mariana Santos Moreda Graça (Master)
Universidade de Aveiro, Portugal
2009/06/06 Application of short-hairspin RNAs in cellular models. Evaluation of cellular and molecular effects on genes that regulate DNA damage tolerance by Western Blotting and PCNA ubiquitylation
(Thesis) Main arguer
 Rui Filipe Silva Cruz (Other)
Universidade de Aveiro, Portugal

Association member

Society Organization name Role
2016/01/01 - 2020/12/31 Animal Sciences Laboratory Association Member
2004/01 - 2020/12 Grupo de Estudos de Envelhecimento Cerebral e Demência (GEECD) Member
2002/01 - 2020/12 Portuguese Neuroscience Society Member
2002/01 - 2020/12 POrtuguese Biochemistry Society Member

Evaluation committee

Activity description
Role 		Institution / Organization Funding entity
2024/05/15 - 2024/10/15 Evaluation of FCT PhD research fellowships
Evaluator
 Universidade de Aveiro, Portugal Fundação para a Ciência e a Tecnologia

Mentoring / Tutoring

Topic Student name
2017/07/01 - 2020/12/31 Filipa de Sá Martins
2016/01/01 - 2018/12/31 Maria de Fátima Camões
2016/01/01 - 2017/12/31 José Joaquim de Souza Melo

Other jury / evaluation

Activity description Institution / Organization
2019/10 - 2019/12 Projects evaluator: FWF Austrian Science Fund (FWF- Most 2019 call for Joint Research Projects) Fonds zur Förderung der wissenschaftlichen Forschung, Austria
2018/07 - 2018/08 Grant Evaluator: Projects from the Association France Alzheimer et Maladies Apparenteés Association France Alzheimer et Maladies Apparentées, France
2017/02 - 2017/06 ERC Starting Grants Evaluator European Research Council, Belgium
Distinctions

Award

2022 Cells 2021 Outstanding Reviewer Awards
MDPI AG, Switzerland
2020 Brain Awareness week 2020
Federation of European Neuroscience Societies, Belgium
2019 Best Poster Award
Universidade de Aveiro Instituto de Biomedicina, Portugal
2014 Brain Awareness Week Grant
Federation of European Neuroscience Societies, Belgium
2014 International award of Institut Pasteur
2013 Best Poster Award
Universidade de Aveiro, Portugal
2012 Brain Awareness week Grant
Federation of European Neuroscience Societies, Belgium
2009 FCT Post Doctoral Felow
Fundação para a Ciência e a Tecnologia, Portugal
2005 FCT PhD Fellowship
Fundação para a Ciência e a Tecnologia, Portugal
2004 Research Incentive Award
Fundação AstraZeneca, Portugal
2004 University of Aveiro PhD Fellowship
Universidade de Aveiro, Portugal

Other distinction

2019 Honours of Paul Greegard (Nobel Prize 2000) mentioning our collaboartive work.
2014 Article selection for the OMICS Journal web page
2009 Calouste Gulbenkian Foundation scholarship
Fundação Calouste Gulbenkian, Portugal