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Sofia D. Viana is an integrated Researcher integrated at CIBB – Centre for Innovative Biomedicine and Biotechnology (iCBR/CIBB) and Associate Professor at Polytechnic University of Coimbra (PUC) in the Pharmacology&Natural products areas. She completed her PhD in Biomedical Sciences in 2016 at Institute of Pharmacology and Experimental Therapeutics (IPET - Faculty of Medicine, University of Coimbra), following a MSc in Biochemistry (2011, UC) and two BSc degrees in Biochemistry (2009, UC) and Pharmacy (2002, PUC). After finishing her PhD with a strong focus on the pharmacology of central nervous system and immunology, she secured a Post-Doctoral fellowship (HealthyAging2020) at IPET-UC. Her prominent Bench2Bedside mindset and singular background instilled her with the versatility to incorporate pharmaceutical technological skills for the upcycling of vegetable matrices with no commercial value, fostering their application as prebiotic ingredients with immunonutritional value. In this frame, she focused her attention in eco-friendly biotechnological processing of agrowaste from red fruits given their valuable polyphenolic contents. This path culminated in the recent leadership of the Innovative Therapeutics in Immunometabolic Diseases research team at iCBR. The scope of her vast academic training was instrumental in the design of an innovative biotechnological-based drug delivery system aimed to ease the harm-benefit dilemma within laboratory animals’ oral dosing – HaPILLness project (Principal investigator, 2018). Under this scope, she generated an international patent (4142698, Inventor), along with 2 registered trademarks and 1 prototype. Her work has been successively recognized with several awards in the (inter)national scientific community. From all distinctions, it is worth highlighting the meritorious EPAA Refinement Prize (2021), a European Commission award and the “Best translational research in Neurology” (Pereira Monteiro Prize) from the Portuguese Society of Neurology. With a strong interest in applied science, she is co-founder and CEO of RDefine, a biotechnology-based spin-off stemming from the successful tech transfer of her HaPILLness invention (2023). The company has recently secured pre-seed investment from the National Innovation Agency and Portugal Ventures (INNOV-ID), underscoring the quality and translational value of her research dedicated to the research and development of new pharmacological options from biological and synthetic candidates. In this frame, her proficiency in the medical and pharmaceutical biotechnology fields has been recently recognized by Fundação Santander (2024) through the grant REVERSE - Restoring beta-cell function by engineering extracellular vesicles with microRNAs - aimed to develop a new biotechnological approach targeting the root cause of type 2 diabetes, restoring ß-cell function. Since 2013, Sofia participated as a proactive Researcher in 23 R&D projects and is currently participating in 5 (inter)national competitive projects. Her proficiency and leadership skills are also showcased by several entrepreneurs’ grants. Sofia is (co)author of 41 peer-reviewed full-articles (Q1) and has been responsible for student (co)supervision in various MSc and PhD programmes. Currently, she (co)supervises 4PhD and 5MSc students, being a regular lecturer in MSc/PhD programs from Biomedical Sciences, Pharmacy, Pharmaceutical Biotechnology, Medicinal Chemistry, among others. Understanding the importance of science dissemination, she has participated in numerous (inter)national congresses being (co)author of more than 100 communications. Presently, she is pledged to the international dissemination of Refinement practices across European LAS networks and grass-root communities as well as joining key industrial/academic/NGO stakeholders in scientific seminars and outreach activities (e.g. EARA, ART, European Researchers Night, Pint of Science Festival).
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Identification

Personal identification

Full name
Sofia Andreia Viana
Gender
Female

Citation names

  • Viana SD

Author identifiers

Ciência ID
521B-B11C-CCC3
ORCID iD
0000-0002-1316-1319

Email addresses

  • sofia_viana@estescoimbra.pt (Professional)

Telephones

Telephone
  • 239480071 (Professional)

Addresses

  • Coimbra Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, University of Coimbra, Subunit 1- Pólo III Campus – Health Sciences, Azinhaga de Santa Comba - Celas, 3000-548, Coimbra, Coimbra, Portugal (Professional)
  • Instituto Politécnico de Coimbra, Escola Superior de Tecnologia da Saúde de Coimbra (IPC/ESTESC), Rua 5 de Outubro, 3046-854, São Martinho do Bispo, Coimbra, Portugal (Professional)

Knowledge fields

  • Medical and Health Sciences - Basic Medicine - Pharmacology and pharmacy
  • Medical and Health Sciences - Health Sciences
  • Medical and Health Sciences - Health Sciences - Nutrition, Dietetics

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
French Intermediate (B1) Intermediate (B1) Intermediate (B1) Intermediate (B1)
Education
Degree Classification
2017 - 2018
Concluded
 HEALTHY AGING 2020 (Pós-doutoramento)
Universidade de Coimbra Faculdade de Medicina, Portugal
2012 - 2016/09
Concluded
 Ciências da Saúde - Ciências Biomédicas (Doutoramento)
Major in Ciências Biomédicas
Universidade de Coimbra Faculdade de Medicina, Portugal
"Modulation of receptors for advanced glycation endproducts network in Parkinson’s disease" (THESIS/DISSERTATION)
 Aprovado com distinção e louvor
2011
Concluded
 Bioquímica (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Striatal dopamine homeostasis, RAGE levels and astrogliosis from mice exposed to MPTP" (THESIS/DISSERTATION)
 18
2009
Concluded
 Bioquímica (Licenciatura)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
 15
2005
Concluded
 Aplicações, síntese e transformação de produtos naturais e afins (Pós-Graduação)
Universidade de Aveiro, Portugal
 12
1997 - 2002
Concluded
 Farmácia (Licenciatura)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
 16
Affiliation

Science

Category
Host institution 		Employer
2023/07/01 - Current Researcher (Research) RDefine (Technology-based Spin-off), Portugal
2018/12 - Current Researcher (Research) Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia, Portugal
2017/05 - 2018/11 Postdoc (Research) Universidade de Coimbra Faculdade de Medicina, Portugal
CNC.IBILI, Portugal
2011/10 - 2016/03 Researcher (Research) Fundação para a Ciência e a Tecnologia, Portugal
Universidade de Coimbra Faculdade de Medicina, Portugal
2010/10 - 2011/09 Researcher (Research) Universidade de Coimbra Faculdade de Medicina, Portugal

Teaching in Higher Education

Category
Host institution 		Employer
2018 - Current Visiting Professor (University Teacher) Universidade de Coimbra, Portugal
Universidade de Coimbra Faculdade de Medicina, Portugal
(...)
2017/12/01 - Current Adjunct Teacher (Polytechnic Teacher) Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2011 - 2017 Invited Adjunct Teacher (Polytechnic Teacher) Instituto Politécnico de Coimbra, Portugal
2004 - 2011 Invited Assistant (Polytechnic Teacher) Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal

Positions / Appointments

Category
Host institution 		Employer
2021/11/24 - Current Member of Scientific-Technical Council Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2021/05/26 - Current Scientific Coordinator - Master in Pharmacy Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2021/04/23 - Current Director of the Applied Research Unit Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2011 - Current Coordenação de unidades curriculares Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2021 - 2023 Membro do Conselho Eco-Escolas Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
Projects

Grant

Designation Funders
2017 - 2019 HEALTHY AGING 2020
HealthyAgeing2020 BID 1.3
Post-doc Fellow
Universidade de Coimbra Faculdade de Medicina, Portugal
 European Regional Development Fund
2012/01 - 2016/04 The role of RAGE on metamphetamine induced striatal dysfunction: Applications for Parkinson's disease
SFRH/BD/78166/2011
PhD Student Fellow
Fundação para a Ciência e Tecnologia (FCT, Portugal)
Concluded

Contract

Designation Funders
2022/07 - Current MitoBOOST v2.0: Proof of Concept for the Use of Mitochondria-Targeted Polyphenols to Treat Non-Alcoholic Fatty Liver Disease
CENTRO-01-0145-FEDER-181226
Universidade de Coimbra Faculdade de Medicina, Portugal
Concluded
2023/01/01 - 2026/12/31 CHAengeing: Connected Hubs in Ageing: Healthy Living to Protect Cerebrovascular Function
HORIZON-WIDERA-2022-ACCESS-04-01
Researcher
Universidade de Coimbra Faculdade de Medicina, Portugal
Ongoing
2021/01/01 - 2025/12/31 Center for Innovative Biomedicine and Biotechnology - Associate Laboratory
LA/P/0058/2020
10.54499/LA/P/0058/2020
Universidade de Coimbra, Portugal

Universidade de Coimbra Instituto de Investigação Clínica e Biomédica de Coimbra, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2022/12/02 - 2024/12/02 Translational Research: PILL tech - changing preclinical CNS paradigms through a stress-free oral drug dosing tool
SPN2022
Principal investigator
Sociedade Portuguesa de Neurologia, Portugal
 Sociedade Portuguesa de Neurologia
Ongoing
2024/05/17 - 2024/05/24 Start the Journey to Entrepreneurship
KA220-HED-C94C480A
Researcher
Universidade de Coimbra, Portugal
 Erasmus Plus
Ongoing
2022 - 2024 Biomarkers for gadolinium renal injury
2022.08400.PTDC
Researcher
Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2022 - 2024 An Innovative Transdermal Heart-targeted Drug Delivery Strategy
2022.05810.PTDC
Researcher
Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2022/10 - 2023/10 HaPILLness: Validação de uma tecnologia (PILL Tech) para refinamento do doseamento oral de roedores de experimentação
INOVC+
Principal investigator
Universidade de Coimbra, Portugal

Instituto Politécnico de Coimbra, Portugal
Concluded
2022/06/09 - 2023/06/30 AGIR4Innovation: Transfer of knowledge, technology, and innovation to inland territories
POCI-01-0246-FEDER-181326
Researcher
Instituto Politécnico de Coimbra, Portugal
Concluded
2018/07/26 - 2022/07/25 Exercício físico e depressão: efeito antidepressivo dos exersomas
PTDC/SAU-DES/30786/2017
Universidade de Coimbra, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2020 - 2022 CAPEOSBAC - Tailored microenCAPsulation technology for Extreme Oxygen-Sensitive BACteria with beneficial effects on gut microbiota: Production, stability and functionality enhancements in various carriers
PT2020-SAICT-PTDC/ICDT-031400 PTDC/BAA-AGR/31400/2017
Researcher
Fundação para a Ciência e a Tecnologia
Concluded
2018 - 2022 FRUITIFY - Use of blueberry juice as a nutraceutical strategy targeting gut dysbiosis to prevent the progression from prediabetes to diabetes
POCI-01-0145-FEDER-031712
Researcher
Universidade de Coimbra Faculdade de Medicina, Portugal
 Fundação para a Ciência e Tecnologia (FCT, Portugal)
Concluded
2018 - 2022 MOOD EXERsomes - Speed, crash and run: exersomes boost neuroenergetics and mood in mice on speed
POCI-01-0145-FEDER-030786
Researcher
Fundação para a Ciência e Tecnologia (FCT, Portugal)
Concluded
2018 - 2022 MercuMemory - Neurotoxicity of methylmercury in the neurogenic niches of the adult brain: impact for long-term neurodegeneration and cognitive decline
POCTI-FEDER-02/SAICT/2017/31699
Researcher
Fundação para a Ciência e Tecnologia (FCT, Portugal), Portugal
 Fundação para a Ciência e Tecnologia (FCT, Portugal)
Concluded
2018 - 2022 DIAL4LIFE - Dialysis membranes by design: targeting neutrophil elastase to reduce inflammation/oxidative stress in end-stage renal disease.
PT2020-SAICT-PTDC/ICDT-031322 PTDC/MEC-CAR/31322/2017
Integration into Research Grant Fellow
Fundação para a Ciência e Tecnologia (FCT, Portugal)
2018 - 2022 PHENOLIVA - Contribution of olive and olive oil polyphenolic compounds to the prevention of cardiovascular diseases.
PT2020-SAICT-PTDC/ICDT-032492 POCI-01-0145-FEDER-032492
 Fundação para a Ciência e Tecnologia (FCT, Portugal)
2018 - 2022 NephroCardio Risk - Reliable biomarkers of chronic kidney disease and of the associated cardiovascular risk. Construction of (bio)sensors for the selected biomarkers
Norte-01-0145-FEDER-000024
2018 - 2022 INOVC2020 - The therapeutic potential of Vaccinium corymbosum L. senescent leaves (blueberries) in Multiple Sclerosis: adding value to a regional agro-waste product.
INOVC2020-SAAC-CENTRO-46-2016-01-5625
Principal investigator
Comissão de Coordenação e Desenvolvimento Regional do Centro
2021 - 2021/12 GluVac-COVID19 – Explorar o potencial de ß-glucanas como adjuvantes imunológicos no desenvolvimento de vacinas para a Covid-19
59949
Researcher
Universidade Católica Portuguesa, Portugal
 Fundação para a Ciência e Tecnologia (FCT, Portugal)
2019/01/01 - 2019/12/31 CNC. IBILI
UID/NEU/04539/2019
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Universidade de Coimbra, Portugal

Universidade de Coimbra Instituto de Ciências Nucleares Aplicadas à Saúde, Portugal

Universidade de Coimbra Instituto de Investigação Clínica e Biomédica de Coimbra, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2015 - 2016 Pinning down TRVP1: acupuncture analgesia
PT0018.D.03-BST2015/FMUC FEDER
Researcher
Universidade de Coimbra Faculdade de Medicina, Portugal

Santander Totta, Portugal
Universidade de Coimbra Faculdade de Medicina
Concluded
2015 - 2016 O bloqueio dos receptores A2A para a adenosina conrola a plasticidade sináptica aberrante responsável pelos sintomas não motores (cognitivos e de humor) na doença de Parkinson
Nº CAPES: 8543/14-3
Researcher
Fundação para a Ciência e Tecnologia (FCT, Portugal)
2014/03 - 2015/06 Stepping on the RAGE network: physical exercise in the management of Parkinson ´s disease
EXPL/DTP-DES/0104/2013
Researcher
Fundação para a Ciência e a Tecnologia, Portugal
Concluded
2014 - 2015 Clinical Trial HERA: A randomised three-arm multi-centre comparison of 1 year and 2 years of Herceptin in woman with HER2-positive primary breast cancer who have completed adjuvant chemotherapy
Protocol BO 16348/BIG 01-01 ROCHE
Technical development
Concluded
2013 - 2015 Exercício físico na Doença de Parkinson: modulação da função dos receptores dos produtos de glicação
EXPL/DTP-DES/0104/2013
Researcher
Fundação para a Ciência e Tecnologia (FCT, Portugal)
Concluded
2012 - 2013 Is methamphetamine self-administration associated with the activation of the brain receptor for advanced glycation end product (RAGE)?
Projecto FCP011
Projecto FCP011
Researcher
Universidade de Coimbra Faculdade de Medicina, Portugal
 Fundação para a Ciência e Tecnologia (FCT, Portugal)
Concluded
Outputs

Publications

Book chapter
  1. Pereira, F.C.; Viana, S.D.; Mendes, Patrícia; Ali, Syed F.; Fontes-Ribeiro, Carlos A.. "Caudate-Putamen: Dopamine Homeostasis and Astrocyte Activation in Methamphetamine Abuse". In Horizons in Neuroscience Research, 1-28. USA: Nova Science Publisher, 2012.
    Published
Conference abstract
  1. Lousa, Irina; Belo, Luís; Viana, Sofia D; Vieira, Pedro; Vala, Helena; Santos-Silva, Alice; Reis, Flávio. "Circulating beta-trace protein versus creatinine as markers of early kidney (dys)function in the nx-induced rat model of chronic kidney disease". 2023.
    10.1093/ndt/gfad063c_4154
  2. Nunes, S; Viana, S; Preguiça, I; Alves, A; Fernandes, R; Jarak, I; Carvalho, R; et al. "Unraveling the hepatoprotective effects of blueberries in a hypercaloric diet-induced rat model of prediabetes by metabolomic and transcriptomic approaches". Paper presented in AnnualMeeting 2021 Coimbra Heath School - Global Health: New Trends, 2021.
    10.1093/eurpub/ckab120.106
  3. Alves, André; Vieira, Pedro; Nunes, Sara; Preguiça, Inês; Ormonde, Beatriz; Gomes, Pedro; Reis, Flávio; Viana, Sofia. "The impact of refined food processing on the kidney - preclinical evaluation". Paper presented in inAnnual Meeting 2021 Coimbra Heath School - Global Health: New Trends, Coimbra, 2021.
    https://doi.org/10.1093/eurpub/ckab120.107
  4. Lousa, Irina; Valente, Maria João; Rocha, Susana; Viana SD; Preguiça, Inês; Mira, Filipe; Nogueira, Rui; et al. "MO472A PRELIMINARY STUDY OF POTENTIAL BIOMARKERS FOR EARLY DIAGNOSIS IN CHRONIC KIDNEY DISEASE". 2021.
    10.1093/ndt/gfab090.0034
  5. André Alves; Inês Preguiça; Adelaide Barbosa; Pedro Vieira; Diana Martins; Sara Nunes; Sofia D. Viana; Flavio Reis. "Blueberry juice improved the metabolic profile in a prediabetic rat model induced by a hypercaloric diet without renoprotection, Nephrology Dialysis Transplantation, Volume 35, Issue Supplement_3, June 2020". 2020.
    10.1093/ndt/gfaa142.P0997
  6. Susana Coimbra; Flavio Reis; Sara Nunes; Sofia D. Viana; Maria João Valente; Susana Rocha; Cristina Catarino; et al. "Impact of achieving LDL cholesterol lower than 100mg/dl with statins, on lipid profile and inflammation in end-stage renal disease patients, Nephrology Dialysis Transplantation, Volume 35, Issue Supplement_3, June 2020". 2020.
    https://doi.org/10.1093/ndt/gfaa142.P1581
  7. Rosa, Maria J.V.; Rocha, Susana; Lousa, Irina; Reis, Flávio; Nunes, Sara; Viana, Sofia D.; Preguiça, ; Santos-Silva, Alice. "Panel of sensitive biomarkers of the primary response to renal injury for na early diagnosis of chronic kidney disease.". Paper presented in Nephrology Dialysis Transplantation, 2020.
    Published • 10.1093/ndt/gfaa142.P0739
  8. Alves, A; Preguiça, I; Barbosa, A; Vieira, P; Martins, D; Nunes, S; Viana, S; Reis, F. "Blueberries effects in experimental diet-induced prediabetes: a focus on renal impairment, European Journal of Public Health, Volume 30, Issue Supplement_2, June 2020". 2020.
    Published • 10.1093/eurpub/ckaa040.055
  9. Viana SD; Valente, Maria João; Rocha, Susana; Lousa, Irina; Reis, Flávio; Nunes, Sara; D. Viana, Sofia; et al. "P0739PANEL OF SENSITIVE BIOMARKERS OF THE PRIMARY RESPONSE TO RENAL INJURY FOR AN EARLY DIAGNOSIS OF CHRONIC KIDNEY DISEASE". 2020.
    10.1093/ndt/gfaa142.p0739
  10. Viana SD; Martins B.; Nunes, Sara; Palavra F.; Preguiça, Inês; Alves A.; Nóbrega C.; et al. "A novel semi-solid pill for stress-free voluntary oral drug administration in experimental rodents". Paper presented in 14th FELASA (Federation of European Laboratory Animal Science Associations) congress, Praga, 2019.
    Published • 10.1177/0023677219839199
  11. Coimbra, Susana; Reis, Flávio; Nunes, Sara; Viana, Sofia; Valente, Maria João; Rocha, Susana; Catarino, Cristina; et al. "Effects on statins therapy on LDL subfractions and inflammation, in end-stage renal disease patients on dialysis.". Paper presented in 56th ERA-EDTA Congress, Budapest, 2019.
    Published • 10.1093/ndt/gfz106.fp730
  12. Nunes, S; Viana, S; Rolo, A; Palmeira, C; André, A; Cavadas, C; Pintado, M; Reis, F. "Blueberry juice as a nutraceutical approach to prevent prediabetes progression in an animal model: focus on hepatic steatosis". Paper presented in Annual meeting ESTeSC 2019. “Primary health care: Challenges and Oportunities", Coimbra, 2019.
    10.1093/eurpub/ckz034.011
  13. Nunes, Sara; Viana SD; Rolo, Anabela Pinto; Palmeira, Carlos; André, MA; Cavadas, Claudia; Pintado, Maria Manuela; Reis, Flávio. "Effects of blueberry juice intake on liver injury progression in a hypercaloric diet-induced prediabetic rat model". Paper presented in 12th MiP/MitoEAGLE Training School, Coimbra, 2019.
  14. Nunes, Sara; Viana SD; Castela, Ana; Rolo, Anabela Pinto; Palmeira, Carlos; André, MA; Cavadas, Claudia; Pintado, MM; Reis, Flávio. "Blueberry juice attenuates liver injury progression in a rat model of diet-induced prediabetes". Paper presented in 1st Meeting in Translational Pharmacology (38th Spanish Society of Pharmacology meeting/9th Spanish Society of Pharmacogenetics and Pharmacogenomics meeting), Santiago de Compostela, 2018.
    Published • https://doi.org/10.1111/bcpt.13084
  15. Coimbra, Susana; Reis, Flávio; Nunes, Sara; Viana, Sofia D.; Rocha, Susana; Santos-Silva., Alice. "Atherogenic properties of ldl particles in ESRD patients on hemodialysis". Paper presented in 55th ERA-EDTA congress, Copenhagen, 2018.
    Published • https://doi.org/10.1093/ndt/gfy104.SP261
  16. Pereira FC; Viana SD; Fontes-Ribeiro C. "Brain innate immunity kindled by dopaminergic toxicants". Paper presented in 53rd Congress of the European Societies of Toxicology. Toxicology letters., Bratislava, 2017.
    Published
  17. Silva, A.L.; Viana SD; Pita, I.; Lemos, C.; Fontes-Ribeiro, Carlos A.; Prediger, R.D.; Pereira, F.C.; Santos, S.. "Impaired gut dopaminergic function in an experimental Parkinson rat model". Paper presented in 51st Congress of the European Societies of Toxicology (EUROTOX), Porto, 2015.
    Published • 10.1016/j.toxlet.2015.08.908
  18. Pereira FC; Viana SD; Fernandes RC; Scodato R; Portugal, CC; Silva AM; Carvalho F; Ali SF; Fontes-Ribeiro CA. "Quiescent RAGE in dysfunctional striata from MPTP-treated mice". Paper presented in Society for Neuroscience, 2014. Program No. 794.14/J8 2014 Neuroscience Meeting Planner., Washington, DC, 2014.
    Published
  19. Fontes-Ribeiro, Carlos A.; Neves, Ana F.; Freitas, Hugo J.; Dias, Ana I.; Mendes, Sheena M.; Viana SD; Nunes, Sara; Pereira, Frederico C.. "Dopaminergic and serotonergic dysfunctions induced by methamphetamine in mice are decreased by aerobic exercise". Paper presented in 26th ECNP Congress, Barcelona, 2013.
    Published • 10.1016/S0924-977X(13)70357-2
  20. Fontes Ribeiro, C.A.; Silva, Carlos; Neves, Ana F.; Freitas, Hugo J.; Dias, Ana I.; Mendes, Sheena M.; Pita, I.; et al. "Acute methamphetamine exposure induces long-lasting depressive-like behavior in mice". Paper presented in 26th ECNP Congress, Barcelona, 2013.
    Published • 10.1016/S0924-977X(13)70394-8
  21. Silva CD.; Pita I.; Neves AF; Dias AI; Freitas HJ; Mendes SM; Viana SD; et al. "Prolonged depressive-like behavior in mice exposed to a bolus injection of methamphetamine". Paper presented in Neuroscience Meeting Planner Program No. 542.26. 2013. Online, San Diego, 2013.
    Published
  22. Viana SD; Silva AM; Portugal, CC; Socodato R; Ali SF; Fontes-Ribeiro CA; Pereira FC. "RAGE down-regulation: an early event in striatal dysfunction in a mouse model of Parkinson’s disease". Paper presented in 6th European Congress of Pharmacology. Proceedings of the British Pharmacological Society. Available in E-journal of the British Pharmacological Society (pA2 online, Granada, 2012.
    Published
  23. Silva, A.L.; Viana SD; Fontes-Ribeiro, Carlos A.; Pereira, F.C.. "Sitagliptin does not protect against MPTP-induced dopaminergic striatal toxicity.". Paper presented in 6th European Congress of Pharmacology, Granada, Spain, 2012.
    Published
  24. Cunha-Oliveira T; Viana SD; Travassos AS; Nunes, Sara; Silva, C.; Rego AC; Ali SF; Fontes-Ribeiro CA; Pereira FC. "Acute methamphetamine intoxication evokes deregulation of striatal glutamatergic/gabaergic homeostasis in mice". Paper presented in 8th Forum of neuroscience. Federation of European Neuroscience Societies. FENS Abstract., 2012.
  25. Pereira FC; Viana SD; Nunes, Sara; Cunha-Oliveira T; Travassos AS; Silva, C.; Silva AM.; et al. "Effect of a single high-dose of methamphetamine on striatal alpha-synuclein, RAGE, neurochemical levels and motor coordination in mice". Paper presented in Annual Meeting of Society for Neuroscience (SFN). Program No. 372.02. 2011 Neuroscience Meeting Planner, Washington DC, 2011.
    Published
Conference paper
  1. Susana Coimbra; Flávio Reis; Sara Nunes; Sofia D. Viana; Maria João Valente; Susana Rocha; Cristina Catarino; et al. "IMPACT OF ACHIEVING LDL CHOLESTEROL LOWER THAN 100 MG/DL WITH STATINS, ON LIPID PROFILE AND INFLAMMATION IN END-STAGE RENAL DISEASE PATIENTS". 2020.
    Published • 10.1093/ndt/gfaa142.p1581
Conference poster
  1. Pedro Vieira; Carolina Ferreira; Nunes, Sara; Inês Preguiça; Alves, André; Jani Almeida; Vera Alves; et al. "Immunophenotypic features of intestinal mucosa in the non-obese high-fat/streptozotocin-induced T2DM model". Paper presented in V SPCAL Congress “LAS for all: Laboratories, Animals and Scientists”, 2024.
  2. Carolina Ferreira; Filipe Palavra; Inês Preguiça; Alves, André; Pedro Vieira; Nunes, Sara; Ângela de Jesus; et al. "A gut feeling about the cuprizone-induced mouse model of multiple sclerosis". Paper presented in V SPCAL Congress “LAS for all: Laboratories, Animals and Scientists”, 2024.
  3. Alves, André; Pedro Vieira; Inês Preguiça; Carolina Ferreira; Nunes, Sara; Gomes, Pedro; Solange Semião; et al. "Impact of refined diets on the wistar rat: exploring dysmetabolic phenotypes through the lens of intestinal microbiota and kidney function". Paper presented in V SPCAL Congress “LAS for all: Laboratories, Animals and Scientists”, 2024.
  4. P. Vieira; Nunes, Sara; Inês Preguiça; Carolina Ferreira; Alves, André; Jani Almeida; Helena Sá; et al. "Imunomodulação Intestinal E Benefícios Metabólicos De Uma Fibra Prebiótica Proveniente De Desperdícios Agrícolas Do Mirtilo Ensaio Em Modelo Animal De Diabetes Mellitus Tipo 2". Paper presented in 19º Congresso Português de Diabetes, 2023.
  5. Nunes, Sara; Ferreira, Gonçalo; Pedro Vieira; Alves, André; Inês Preguiça; Beatriz Ormonde; Solange Semião; et al. "Impacto De Dietas Refinadas No Estabelecimento De Um Modelo De Pré Diabetes Em Rato Foco Em Mecanismos Indutores De Esteatose Hepática". Paper presented in 19º Congresso Português de Diabetes, 2023.
  6. Alves, André; Inês Preguiça; Carolina Ferreira; Nunes, Sara; Gomes, Pedro; Solange Semião; Ribeiro, Tânia; et al. "Efeito De Dietas Refinadas Na Indução De Doença Metabólica Em Rato Destaque Para O Impacto Na Microbiota Intestinal E Na Função Renal". Paper presented in 19º Congresso Português de Diabetes, 2023.
  7. Inês Preguiça; Nunes, Sara; Pedro Vieira; Alves, André; Filipe Palavra; Flavio Reis; Sofia D. Viana. "Pill Tech Re(De)Finindo O Doseamento Oral Em Ensaios Pré Clínicos De Doença Metabólica In Vivo". Paper presented in 19º Congresso Português de Diabetes, 2023.
  8. Ferreira, Gonçalo; Pedro Vieira; Alves, André; Nunes, Sara; Inês Preguiça; Beatriz Ormonde; Solange Semião; et al. "Impacto Metabólico Da Suplementação Com Sumo De Mirtilo Num Modelo De Pré Diabetes Em Rato Induzido Por Dieta". Paper presented in 19º Congresso Português de Diabetes, 2023.
  9. Pedro Vieira; Preguiça, Inês; Alves, André; Jesus, Ângela; Costa, Vânia; Viana SD; Reis, F; Paiva-Martins, Fátima. "Protective effect of oleacein in the apoE-KO Mice Model of Atherosclerosis". Paper presented in 4th International Symposium on Lipid Oxidation and Antioxidants 2022, 2022.
  10. Sara Nunes; Sofia D. Viana; Inês Preguiça; André Alves; Rosa Fernandes; João S. Teodoro; Ivana Jarak; et al. "Efeitos do mirtilo na pré-diabetes em modelo animal ¿ destaque para o impacto na microbiota intestinal e no metabolismo hepático.". Paper presented in 18º Congresso Português de Diabetes, 2022.
  11. Nunes, Sara; Sofia D. Viana; Inês Preguiça; André Alves; Artur Figueirinha; Lígia Salgueiro; Cláudia Cavadas; Maria Manuela Estevez Pintado; Flávio Reis. "Blueberry juice ameliorates experimental hepatic steatosis in prediabetes.". Paper presented in Encontro de Química dos Alimentos, 2021.
  12. Nunes, Sara; Viana, Sofia D.; Preguiça, Inês; Alves, André; Fernandes, Rosa; Jarak, Ivana; Carvalho, Rui A.; et al. "Blueberry juice prevents prediabetes progression in a hypercaloric diet-induced rat model through the modulation of hepatic mitochondrial bioenergetics and metabolic pathways.". Paper presented in 1º Congresso da Rede de Instituições do Ensino Superior para a Salvaguarda da Dieta Mediterrânica, 2021.
  13. Nunes, Sara; Viana, Sofia D.; Preguiça, Inês; Alves, André; Fernandes, Rosa; Jarak, Ivana; Carvalho, Rui A.; et al. "Hepatoprotective effects of blueberry juice in a prediabetic rat model induced by a hypercaloric diet - a molecular aproach.". Paper presented in 17º Congresso Português de Diabetes, Vilamoura 11-17 Março 2021, 2021.
  14. Viana SD. "Efficiency dresses green: enzyme-assisted processing of agrowasted vaccinium leaves". Paper presented in Annual Meeting 2020 (Saúde 4.0: Desenhar a Saúde de Amanhã), 2020.
  15. Viana SD. "Putative Harmful Effects of Blueberries' Chronic Supplementation in Healthy Conditions". Paper presented in Annual Meeting 2020 (Saúde 4.0: Desenhar a Saúde de Amanhã), 2020.
  16. Nunes, Sara; Sofia D. Viana; André Alves; Preguiça, Inês; Rosa Fernandes; Anabela Pinto Rolo; Carlos Palmeira; et al. "Impacto de uma estratégia não-farmacológica na disfunção hepática pré-diabética - estudo do sumo de mirtilos em ratos alimentados com dieta hipercalórica". Paper presented in 16.º Congresso Português de Diabetes, 2020.
  17. Catita, José António Morais; Julie Reis; Mariana Rodrigues; Edna Soares; Sofia D. Viana; Nuno Lima; Tânia Soares Martins; et al. "The Impact of Chronic Aerobic Physical Exercise on Emotional Behavior, Neurochemistry and Circulating Extracellular Vesicles". Paper presented in 50.ª Reunião da Sociedade Portuguesa de Farmacologia, 38.ªReunião de Farmacologia Clínica e 19.ª Reunião de Toxicologia, 2020.
  18. Alves, André; Preguiça, Inês; Barbosa, Adelaide; Vieira, Pedro; Martins, Diana; Nunes, Sara; Viana SD; Reis, Flávio. "Efeitos renais do sumo de mirtilo num modelo de rato pré-diabético induzido por dieta hipercalórica". Paper presented in 16º Congresso Português de Diabetes, 2020.
  19. Preguiça, Inês; Martins, Beatriz; Nunes, Sara; Alves, André; Palavra, Filipe; Fernandes, Rosa; Santos, Sónia; Reis, Flávio; Viana SD. "A novel semi-solid pill for voluntary oral drug administration in experimental rodents". Paper presented in Centre for Innovative Biomedicine and Biotechnology (CIBB) Congress, 2019.
  20. Julie Reis; Mariana Rodrigues; Edna Filipa Pais Soares; Hugo Ferreira; Ines Pita; Sofia D. Viana; Cristina Lemos. "Aerobic Physical Exercise Characterization: Extracellular Vesicles, Emotions and Neurochemistry". Paper presented in 2019 International Conference on Computational Intelligence Methods for Bioinformatics and Biostatistics, 2019.
  21. Reis, Julie; Rodrigues, Mariana; Ferreira, Hugo R. S.; Pita, Inês; Viana SD; Lemos, Cristina; Lima, Nuno; et al. "Emotional, neurochemical and extracellular vesicles signature of aerobic physical exercise". Paper presented in Aging Models, Mechanisms and Therapies Conference, 2019.
  22. Nunes, Sara; Viana, Sofia D.; Reis, Flávio. "Uma abordagem nutracêutica dirigida à pré-diabetes baseada no sumo de mirtilo". Paper presented in 15º Congresso Português de Diabetes, 2019.
  23. Nunes, Sara; Viana, Sofia D.; Reis, Flávio. "Uma abordagem nutracêutica dirigida à pré-diabetes baseada no sumo de mirtilo ¿ Impacto no perfil metabólico e na integridade da barreira intestinal num modelo animal induzido por dieta hipercalórica". Paper presented in 15º Congresso Português de Diabetes. Vilamoura, Portugal 8-10 de Março, 2019., 2019.
  24. Barbosa, Adelaide; Alves, André; Nunes, Sara; Preguiça, Inês; Viana, Sofia D.; Reis, Flávio; Viana SD; Reis, Flávio. "Effects of blueberry juice in a rat model of early diabetic nephropathy induced by high-fat diet.". Paper presented in Centre for Innovative Biomedicine and Biotechnology (CIBB) Congress, Coimbra, 2019.
  25. Barbosa, Adelaide; Alves, André; Nunes, Sara; Preguiça, Inês; Viana, Sofia D.; Reis, Flávio. "Effects of blueberry juice (BJ)in a rat model of early diabetic nephropathy induced by high-fat diet". Paper presented in Centre for Innovative Biomedicine and Biotechnology (CIBB) Congress, 2019.
  26. F. C. Pereira; L.C. Fernandes; M. Campeão; I. Pita; C. Lemos; S. F. Ali; F. Carvalho; C. A. Fontes Ribeiro; S. D. Viana. "Early behavioral and glial signature of the new psychoactive substance MDPV in mice". Paper presented in Society for Neuroscience, 2018.
  27. Flávio Reis; Sara Nunes; Sofia D. Viana; Ana Burgeiro; Eugénia Carvalho; Frederico C. Pereira; Maria Alexandra André; et al. "Alterações cardíacas precoces num modelo de pré-diabetes induzida por dieta hipercalórica - estudo molecular e de imagem funcional". Paper presented in 14º Congresso Português de Diabetes, 2018.
  28. Pereira FC; Viana SD; Valero J; Rodrigues-Santos P; Couceiro P; Silva AM; Carvalho F.; Ali SF; Fontes-Ribeiro CA. "Upregulation of inhibitory rage variants in striatal astrocytes in early experimental parkinson’s disease". Paper presented in Society for Neuroscience Meeting, 2016.
  29. Viana SD; Valero, Jorge; Rodrigues-Santos, Paulo; Couceiro, Patrícia; Silva, Andréa M.; Carvalho, Félix; Ali, Syed F.; Fontes Ribeiro, C.A.; Pereira, F.C.. "EnRAGEd pre-gliotic striatal astrocytes in MPTP mice". Paper presented in VII Annual Meeting of IBILI “New trends in biomedical research”, 2015.
  30. Viana SD; Pereira FC; Fernandes R.; Canas P; Socodato R; Portugal C; Silva A.; et al. "Unresponsive striatal S100B/RAGE axis upon MPTP". Paper presented in Annual meeting of IBILI, Faculty of Medicine, University of Coimbra, 2014.
  31. Viana SD; Fernandes, Rosa C.; Canas, Paula M.; Silva, Andréa M.; Camila Portugal; Renato Socodato; Carvalho, Félix; et al. "Unaltered S100B/RAGE axis in dysfunctional striata from MPTP-treated mice.". Paper presented in XVIII Congresso da Sociedade Portuguesa de Bioquímica, 2014.
  32. Viana SD; Fernandes, Rosa C.; Canas, Paula M.; Silva, Andréa M.; Camila Portugal; Renato Socodato; Carvalho, Félix; et al. "The quiet neuronal RAGE in a storming dysfunctional striata under a chronic MPTP challenge". Paper presented in 6th Annual meeting of IBILI, 2014.
  33. Nunes, Sara; Soares, E.; Fernandes J; Viana SD; Carvalho, E.; Pereira FC; Reis, F.. "Early cardiac changes in a rat model of prediabetes: brain natriuretic peptide overexpression seems to be the best marker". Paper presented in V Annual Meeting of IBILI, 2013.
  34. Pita IR; Silva CD; Neves AF; Viana SD; Fontes Ribeiro CA; Pereira FC. "Antidepressant effects of treadmill exercise in mice submitted to a single neurotoxic dose of methamphetamine". Paper presented in V Annual Meeting of IBILI, 2013.
  35. Soares, E.; Nunes, Sara; Prediger RD; Viana SD; Carvalho, E.; Cunha RA; Fontes-Ribeiro CA; Reis, F.; Pereira FC. "Spatial memory impairments in a pre-diabetic rat model". Paper presented in 4th PF2MUC Symposium, 2013.
  36. Fontes-Ribeiro CA; Neves AF; Freitas HJ; Dias AI; Mendes SM; Viana SD; Nunes, Sara; Pereira FC. "Aerobic exercise recovers dopaminergic and serotonergic dysfunction in methamphetamine-intoxicated mice". Paper presented in 18th Annual Congress of the European College of Sport Science.Barcelone, Spain., 2013.
  37. Soares, E.; Nunes, Sara; Viana SD; Prediger, Rui Daniel; Fontes-Ribeiro, Carlos A.; Pereira, F.C.; Reis, F.. "Memory deficits in a pre-diabetic rat model". Paper presented in IV Annual Meeting of IBILI “From cell biology to in vivo molecular and functional imaging”, 2012.
  38. Neves, Ana F.; Freitas, Hugo J.; Viana SD; Nunes, S.; Pereira, F.C.; Fontes-Ribeiro, Carlos A.. "Neuroregenerative effect of exercise on monoaminergic neurodegeneration evoked by methamphetamine". Paper presented in IV Annual Meeting of IBILI “From cell biology to in vivo molecular and functional imaging, 2012.
  39. Dias, Ana I.; Mendes, Sheena M.; Viana SD; Nunes, Sara; Pereira, F.C.; Fontes Ribeiro, Carlos A.. "Physical Exercise: a neuroprotective strategy in a model of methamphetamine-induced monoaminergic toxicity?". Paper presented in IV Annual Meeting of IBILI “From cell biology to in vivo molecular and functional imaging”, 2012.
  40. Viana SD; Silva, Andréa M.; Camila Portugal; Renato Socodato; Fontes-Ribeiro, Carlos A.; Pereira, F.C.. "RAGE down-regulation: an early cellular response triggered by MPTP". Paper presented in 2nd PF2MUC Symposium Changing paradigms of science, 2012.
  41. Viana SD; Silva, Andréa M.; Ali, Syed F.; Fontes-Ribeiro, Carlos A.; Pereira, F.C.. "Up-regulation of TNF-alpha and lipid peroxidation do not translate into altered RAGE levels in striatum of an MPTP mouse model of Parkinson's disease". Paper presented in 3rd Annual Meeting of IBILI, 2011.
  42. Pereira, F.C.; Cunha-Oliveira, Teresa; Viana SD; Travassos, Ana S.; Nunes, S.; Silva, Carlos; Prediger, R.D.; et al. "Striatal glutamatergic/gabaergic homeostasis disruption coexists with normal alpha-synuclein and RAGE expression in mice injected with methamphetamine". Paper presented in Annual Meeting of Society for Neuroscience, 2011.
Journal article
  1. Adelaide Sousa; Andreia Amaro; Vera Marisa Costa; Rui Azevedo; Sara Oliveira; Sofia Viana; Flávio Reis; et al. "Exploring quercetin's protective potential against the pro-inflammatory effects of silver nanoparticles in C57BL/6J mice". Food and Chemical Toxicology (2025): https://doi.org/10.1016/j.fct.2024.115081.
    10.1016/j.fct.2024.115081
  2. Rosendo-Silva, Daniela; Lopes, Eduardo; Monteiro-Alfredo, Tamaeh; Falcão-Pires, Inês; Eickhoff, Hans; Viana, Sofia; Reis, Flávio; et al. "Corrigendum to “The adipose tissue melanocortin 3 receptor is targeted by ghrelin and leptin and may be a therapeutic target in obesity” [Mol. Cell. Endocrinol. 594 (2024), 112367]". Molecular and Cellular Endocrinology 595 (2025): 112410. https://doi.org/10.1016/j.mce.2024.112410.
    10.1016/j.mce.2024.112410
  3. Rosendo-Silva, Daniela; Lopes, Eduardo; Monteiro-Alfredo, Tamaeh; Falcão-Pires, Inês; Eickhoff, Hans; Viana, Sofia; Reis, Flávio; et al. "The adipose tissue melanocortin 3 receptor is targeted by ghrelin and leptin and may be a therapeutic target in obesity". Molecular and Cellular Endocrinology 594 (2024): 112367. https://doi.org/10.1016/j.mce.2024.112367.
    10.1016/j.mce.2024.112367
  4. Azevedo-Silva, João; Amorim, Manuela; Tavares-Valente, Diana; Sousa, Pedro; Mohamath, Raodoh; Voigt, Emily A.; Guderian, Jeffrey A.; et al. "Exploring yeast glucans for vaccine enhancement: Sustainable strategies for overcoming adjuvant challenges in a SARS-CoV-2 model". European Journal of Pharmaceutics and Biopharmaceutics 205 (2024): 114538. https://doi.org/10.1016/j.ejpb.2024.114538.
    10.1016/j.ejpb.2024.114538
  5. Rosendo-Silva, Daniela; Gomes, Pedro Bastos; Rodrigues, Tiago; Viana, Sofia; da Costa, André Nogueira; Scherer, Philipp E.; Reis, Flávio; et al. "Clinical and molecular profiling of human visceral adipose tissue reveals impairment of vascular architecture and remodeling as an early hallmark of dysfunction". Metabolism 153 (2024): 155788. https://doi.org/10.1016/j.metabol.2024.155788.
    10.1016/j.metabol.2024.155788
  6. Ferreira, Carolina; Vieira, Pedro; Sá, Helena; Malva, João; Castelo-Branco, Miguel; Reis, Flávio; Viana, Sofia. "Polyphenols: immunonutrients tipping the balance of immunometabolism in chronic diseases". Frontiers in Immunology 15 (2024): http://dx.doi.org/10.3389/fimmu.2024.1360065.
    10.3389/fimmu.2024.1360065
  7. Ferreira, Gonçalo; Vieira, Pedro; Alves, André; Nunes, Sara; Preguiça, Inês; Martins-Marques, Tânia; Ribeiro, Tânia; et al. "Effect of Blueberry Supplementation on a Diet-Induced Rat Model of Prediabetes—Focus on Hepatic Lipid Deposition, Endoplasmic Stress Response and Autophagy". Nutrients 16 4 (2024): 513. http://dx.doi.org/10.3390/nu16040513.
    10.3390/nu16040513
  8. Mascarenhas-Melo, Filipa; Diaz, Mariana; Gonçalves, Maria Beatriz S.; Vieira, Pedro; Bell, Victoria; Viana SD; Nunes, Sara; Paiva-Santos, Ana Cláudia; Veiga, Francisco. "An Overview of Biosimilars—Development, Quality, Regulatory Issues, and Management in Healthcare". Pharmaceuticals 17 2 (2024): 235. http://dx.doi.org/10.3390/ph17020235.
    10.3390/ph17020235
  9. Salsinha, Ana Sofia; Cima, André; Araújo-Rodrigues, Helena; Viana, Sofia; Reis, Flávio; Coscueta, Ezequiel R.; Rodríguez-Alcalá, Luis Miguel; Relvas, João B.; Pintado, Manuela. "The use of an in vitro fecal fermentation model to uncover the beneficial role of omega-3 and punicic acid in gut microbiota alterations induced by a Western diet". Food & Function 15 11 (2024): 6095-6117. https://doi.org/10.1039/d4fo00727a.
    10.1039/d4fo00727a
  10. Sousa, Adelaide; Azevedo, Rui; Costa, Vera Marisa; Oliveira, Sara; Preguiça, Inês; Viana SD; Reis, Flávio; et al. "Biodistribution and intestinal inflammatory response following voluntary oral intake of silver nanoparticles by C57BL/6J mice". Archives of Toxicology 97 10 (2023): 2643-2657. http://dx.doi.org/10.1007/s00204-023-03558-5.
    10.1007/s00204-023-03558-5
  11. Garcia, Karina; Alves, André; Ribeiro-Rodrigues, Teresa M.; Reis, Flávio; Viana, Sofia. "Analysis of Fluorescent-Stained Lipid Droplets with 3D Reconstruction for Hepatic Steatosis Assessment". Journal of Visualized Experiments 196 (2023): http://dx.doi.org/10.3791/65206.
    10.3791/65206
  12. Daniela Rosendo-Silva; Sofia Viana; Eugénia Carvalho; Flávio Reis; Paulo Matafome. "Are gut dysbiosis, barrier disruption, and endotoxemia related to adipose tissue dysfunction in metabolic disorders? Overview of the mechanisms involved". Internal and Emergency Medicine (2023): http://dx.doi.org/10.1007/s11739-023-03262-3.
    10.1007/s11739-023-03262-3
  13. Irina Lousa; Flávio Reis; Sofia Viana; Pedro Vieira; Helena Vala; Luís Belo; Alice Santos-Silva. "TNFR2 as a Potential Biomarker for Early Detection and Progression of CKD". Biomolecules (2023): https://doi.org/10.3390/biom13030534.
    10.3390/biom13030534
  14. Palavra, Filipe; Viana, Sofia D.; Henriques, Sara; Dinis, João; Martins, João; Madeira, Maria H.; Santiago, Raquel; et al. "Defining milestones for the study of remyelination using the cuprizone mouse model: How early is early?". Multiple Sclerosis and Related Disorders 63 (2022): 103886. http://dx.doi.org/10.1016/j.msard.2022.103886.
    10.1016/j.msard.2022.103886
  15. Alves-Silva, Jorge M.; Zuzarte, Mónica; Marques, Carla; Viana SD; Preguiça, Inês; Baptista, Rui; Ferreira, Cátia; et al. "1,8-Cineole ameliorates right ventricle dysfunction associated with pulmonary arterial hypertension by restoring connexin43 and mitochondrial homeostasis". Pharmacological Research 180 (2022): 106151. http://dx.doi.org/10.1016/j.phrs.2022.106151.
    10.1016/j.phrs.2022.106151
  16. Azimirad, Masoumeh; Noori, Maryam; Raeisi, Hamideh; Yadegar, Abbas; Shahrokh, Shabnam; Asadzadeh Aghdaei, Hamid; Bentivegna, Enrico; et al. "How Does COVID-19 Pandemic Impact on Incidence of Clostridioides difficile Infection and Exacerbation of Its Gastrointestinal Symptoms?". Frontiers in Medicine 8 (2021): http://dx.doi.org/10.3389/fmed.2021.775063.
    10.3389/fmed.2021.775063 • Editor
  17. Nunes, Sara; Viana SD; Preguiça, Inês; Alves, André; Fernandes, Rosa; Teodoro, João S.; Matos, Patrícia; et al. "Blueberry Counteracts Prediabetes in a Hypercaloric Diet-Induced Rat Model and Rescues Hepatic Mitochondrial Bioenergetics". Nutrients 13 12 (2021): 4192. http://dx.doi.org/10.3390/nu13124192.
    10.3390/nu13124192
  18. Li, Yujia; Li, Bin; Wang, Pan; Wang, Qinghua. "Traditional Chinese Medicine, Qingfei Paidu Decoction and Xuanfei Baidu Decoction, Inhibited Cytokine Production via NF-¿B Signaling Pathway in Macrophages: Implications for Coronavirus Disease 2019 (COVID-19) Therapy". Frontiers in Pharmacology 12 (2021): http://dx.doi.org/10.3389/fphar.2021.722126.
    10.3389/fphar.2021.722126 • Editor
  19. Liang, Dongning; Mai, Hanwen; Ruan, Fangyi; Fu, Haiyan. "The Efficacy of Triptolide in Preventing Diabetic Kidney Diseases: A Systematic Review and Meta-Analysis". Frontiers in Pharmacology 12 (2021): http://dx.doi.org/10.3389/fphar.2021.728758.
    10.3389/fphar.2021.728758 • Editor
  20. Zhuang, Tongxi; Li, Wei; Yang, Li; Wang, Zhengtao; Ding, Lili; Zhou, Mingmei. "Gut Microbiota: Novel Therapeutic Target of Ginsenosides for the Treatment of Obesity and Its Complications". Frontiers in Pharmacology 12 (2021): http://dx.doi.org/10.3389/fphar.2021.731288.
    10.3389/fphar.2021.731288 • Editor
  21. Vieira, Pedro; Nunes, Sara; Alves, André; Preguiça, Inês; Figueirinha, Artur; Salgueiro, Lígia; Gomes, Pedro; Viana, Sofia; Reis, Flávio. "Blueberry effects on prediabetic nephropathy - a preclinical in vivo approach". European Journal of Public Health 31 Supplement (2021): http://dx.doi.org/10.1093/eurpub/ckab120.110.
    https://doi.org/10.1093/eurpub/ckab120.110
  22. Nunes, Sara; Vieira, Pedro; Gomes, Pedro; Viana, Sofia D.; Reis, Flávio. "Blueberry as an attractive functional fruit to prevent (pre)diabetes progression.". Antioxidants 10 8 (2021): 1162-1162. https://doi.org/10.3390/antiox10081162.
    Published • 10.3390/antiox10081162
  23. Blas-Valdivia, Vanessa; Franco-Colín, Margarita; Rojas-Franco, Placido; Chao-Vazquez, Alberto; Cano-Europa, Edgar. "Gallic Acid Prevents the Oxidative and Endoplasmic Reticulum Stresses in the Hippocampus of Adult-Onset Hypothyroid Rats". Frontiers in Pharmacology 12 (2021): http://dx.doi.org/10.3389/fphar.2021.671614.
    10.3389/fphar.2021.671614 • Editor
  24. Mafalda Campeão; Luciana Fernandes; Inês R. Pita; Cristina Lemos; Syed F. Ali; Félix Carvalho; Paulo Rodrigues-Santos; et al. "Acute MDPV binge paradigm on mice emotional behavior and glial signature". Pharmaceuticals (2021):
    Accepted
  25. Viana SD. "Is Gut Microbiota Dysbiosis a Predictor of Increased Susceptibility to Poor Outcome of COVID-19 Patients? An Update". Microorganisms 9 1 (2020): 53-53. http://dx.doi.org/10.3390/microorganisms9010053.
    10.3390/microorganisms9010053
  26. Nunes, Sara; Viana, Sofia D.; Preguiça, Inês; Alves, André; Fernandes, Rosa; Teodoro, João S.; Figueirinha, Artur; et al. "Blueberry Consumption Challenges Hepatic Mitochondrial Bioenergetics and Elicits Transcriptomics Reprogramming in Healthy Wistar Rats". Pharmaceutics 12 11 (2020): 1094. http://dx.doi.org/10.3390/pharmaceutics12111094.
    10.3390/pharmaceutics12111094
  27. Viana SD. "Gut Microbiota Dysbiosis–Immune Hyperresponse–Inflammation Triad in Coronavirus Disease 2019 (COVID-19): Impact of Pharmacological and Nutraceutical Approaches". Microorganisms (2020): http://dx.doi.org/10.3390/microorganisms8101514.
    10.3390/microorganisms8101514
  28. Sofia D. Viana; Sara Nunes; Flávio Reis. "ACE2 imbalance as a key player for the poor outcomes in COVID-19 patients with age-related comorbidities – Role of gut microbiota dysbiosis". Ageing Research Reviews 62 (2020): 101123-101123. https://doi.org/10.1016/j.arr.2020.101123.
    10.1016/j.arr.2020.101123
  29. Inês Preguiça; André Alves; Sara Nunes; Rosa Fernandes; Pedro Gomes; Sofia D. Viana; Flávio Reis. "Diet-induced rodent models of obesity-related metabolic disorders—A guide to a translational perspective". Obesity Reviews (2020): https://doi.org/10.1111/obr.13081.
    10.1111/obr.13081
  30. Viana SD. "Crescent-Like Lesions as an Early Signature of Nephropathy in a Rat Model of Prediabetes Induced by a Hypercaloric Diet". Nutrients (2020): http://dx.doi.org/10.3390/nu12040881.
    10.3390/nu12040881
  31. Viana SD. "Diet-Induced Rodent Models of Diabetic Peripheral Neuropathy, Retinopathy and Nephropathy". Nutrients (2020): http://dx.doi.org/10.3390/nu12010250.
    10.3390/nu12010250
  32. Gomes, Pedro; Viana, Sofia D.; Nunes, Sara; Rolo, Anabela P.; Palmeira, Carlos M.; Reis, Flávio. "The yin and yang faces of the mitochondrial deacetylase sirtuin 3 in age-related disorders". Ageing Research Reviews 57 (2020): 100983. http://dx.doi.org/10.1016/j.arr.2019.100983.
    Published • 10.1016/j.arr.2019.100983
  33. Fernandes, Rosa; Viana, Sofia D.; Nunes, Sara; Reis, Flávio. "Diabetic gut microbiota dysbiosis as an inflammaging and immunosenescence condition that fosters progression of retinopathy and nephropathy". Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1865 7 (2019): 1876-1897. http://dx.doi.org/10.1016/j.bbadis.2018.09.032.
    Published • 10.1016/j.bbadis.2018.09.032
  34. Susana Coimbra; Flávio Reis; Sara Nunes; Sofia Viana; Maria João Valente; Susana Rocha; Cristina Catarino; et al. "The Protective Role of Adiponectin for Lipoproteins in End-Stage Renal Disease Patients: Relationship with Diabetes and Body Mass Index". Oxidative Medicine and Cellular Longevity 2019 (2019): 1-11. https://doi.org/10.1155/2019/3021785.
    10.1155/2019/3021785
  35. Coimbra, Susana; Reis, Flávio; Ferreira, Cátia; Nunes, Sara; Viana, Sofia; Catarino, Alice; Rocha-Pereira, Petronila; et al. "Weight loss achieved by bariatric surgery modifies high-density lipoprotein subfractions and low-density lipoprotein oxidation towards atheroprotection". Clinical Biochemistry 63 (2019): 46-53. http://dx.doi.org/10.1016/j.clinbiochem.2018.10.007.
    Published • 10.1016/j.clinbiochem.2018.10.007
  36. Viana SD; Reis F; Alves R. "Therapeutic Use of mTOR Inhibitors in Renal Diseases: Advances, Drawbacks, and Challenges.". Oxidative medicine and cellular longevity (2018): http://europepmc.org/abstract/med/30510618.
    10.1155/2018/3693625
  37. Viana, Sofia D.; Pita, Inês R.; Lemos, Cristina; Rial, Daniel; Couceiro, Patrícia; Rodrigues-Santos, Paulo; Caramelo, Francisco; et al. "The effects of physical exercise on nonmotor symptoms and on neuroimmune RAGE network in experimental parkinsonism". Journal of Applied Physiology 123 1 (2017): 161-171. http://dx.doi.org/10.1152/japplphysiol.01120.2016.
    Published • 10.1152/japplphysiol.01120.2016
  38. Esteves, Ana R.; Arduíno, Daniela M.; Silva, Diana F.; Viana, Sofia D.; Pereira, Frederico C.; Cardoso, Sandra M.. "Mitochondrial Metabolism Regulates Microtubule Acetylome and Autophagy Trough Sirtuin-2: Impact for Parkinson’s Disease". Molecular Neurobiology 55 2 (2017): 1440-1462. http://dx.doi.org/10.1007/s12035-017-0420-y.
    Published • 10.1007/s12035-017-0420-y
  39. Viana, Sofia D.; Valero, Jorge; Rodrigues-Santos, Paulo; Couceiro, Patrícia; Silva, Andréa M.; Carvalho, Félix; Ali, Syed F.; Fontes-Ribeiro, Carlos A.; Pereira, Frederico C.. "Regulation of striatal astrocytic receptor for advanced glycation end-products variants in an early stage of experimental Parkinson's disease". Journal of Neurochemistry 138 4 (2016): 598-609. http://dx.doi.org/10.1111/jnc.13682.
    Published • 10.1111/jnc.13682
  40. Viana, Sofia D.; Fernandes, Rosa C.; Canas, Paula M.; Silva, Andréa M.; Carvalho, Félix; Ali, Syed F.; Fontes Ribeiro, Carlos A.; Pereira, Frederico C.. "Presymptomatic MPTP Mice Show Neurotrophic S100B/mRAGE Striatal Levels". CNS Neuroscience & Therapeutics 22 5 (2016): 396-403. http://www.ncbi.nlm.nih.gov/pubmed/26843141.
    Published • 10.1111/cns.12508
  41. Rego, Â.; Viana, S.D.; Ribeiro, C.A.F.; Rodrigues-Santos, P.; Pereira, F.C.; Rego, Ângela; Viana, Sofia D.; et al. "Monophosphoryl Lipid-A: A Promising Tool for Alzheimer's Disease Toll". Journal of Alzheimer's Disease 52 4 (2016): 1189-1202. http://www.scopus.com/inward/record.url?eid=2-s2.0-84974530211&partnerID=MN8TOARS.
    Published • 10.3233/JAD-151183
  42. Soares, E.; Prediger, R.D.; Nunes, S.; Castro, A.A.; Viana, S.D.; Lemos, C.; De Souza, C.M.; et al. "Spatial memory impairments in a prediabetic rat model". Neuroscience 250 (2013): 565-577. http://dx.doi.org/10.1016/j.neuroscience.2013.07.055.
    Published • 10.1016/j.neuroscience.2013.07.055
  43. Silva, Carlos D.; Neves, Ana F.; Dias, Ana I.; Freitas, Hugo J.; Mendes, Sheena M.; Pita, Inês; Viana, Sofia D.; et al. "A Single Neurotoxic Dose of Methamphetamine Induces a Long-Lasting Depressive-Like Behaviour in Mice". Neurotoxicity Research 25 3 (2013): 295-304. http://dx.doi.org/10.1007/s12640-013-9423-2.
    Published • 10.1007/s12640-013-9423-2
  44. Nunes, Sara; Soares, Edna; Fernandes, João; Viana, Sofia; Carvalho, Eugénia; Pereira, Frederico C; Reis, Flávio. "Early cardiac changes in a rat model of prediabetes: brain natriuretic peptide overexpression seems to be the best marker". Cardiovascular Diabetology 12 1 (2013): 44. http://dx.doi.org/10.1186/1475-2840-12-44.
    Published • 10.1186/1475-2840-12-44
  45. Pereira, Frederico C.; Cunha-Oliveira, Teresa; Viana, Sofia D.; Travassos, Ana S.; Nunes, Sara; Silva, Carlos; Prediger, Rui Daniel; et al. "Disruption of striatal glutamatergic/GABAergic homeostasis following acute methamphetamine in mice". Neurotoxicology and Teratology 34 5 (2012): 522-529. http://dx.doi.org/10.1016/j.ntt.2012.07.005.
    Published • 10.1016/j.ntt.2012.07.005
Thesis / Dissertation
  1. Viana, Sofia Andreia Domingues. "Modulation of receptors for advanced glycation endproducts network in Parkinson's disease". PhD, 2016. http://hdl.handle.net/10316/31666.
  2. Viana SD. "Striatal dopamine homeostasis, RAGE levels and astrogliosis from mice exposed to MPTP". Master, Universidade de Coimbra, 2011.

Intellectual property

Patent
  1. Viana SD; Flavio Reis. 2021. "Semi-Solid Formulation for Voluntary Oral Administration of Bioactive Compounds to Rodents - Application nº PCT/IB2021/053124". Portugal.
    Granted/Issued
Provisional application for patent
  1. 2020. "Semi-Solid Formulation for Voluntary Oral Administration of Bioactive Compounds to Rodents - Pedido provisório de patente nº 116301".
  2. 2018. "Voluntary oral bioactive compounds administration in rodents - Pedido provisório de patente nº 20181000072168".
    Protected

Other

Spin-off company
  1. 2023. RDfine, LDA. Investigação científica e desenvolvimento (investigação e desenvolvimento em biotecnologia). https://rdefine.com/.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2024/02/09 (De/Re)myelination dynamics in cuprizone-induced multiple sclerosis: focus on the gut-neuroimmune axis LIV Reunião Anual da Sociedade Portuguesa de Farmacologia/XLII Reunião de Farmacologia Clínica/XXIII Reunião de Toxicologia
Faculdade de Ciências Médicas-Universidade NOVA de Lisboa (Lisboa, Portugal)
2024/02/08 A tolerogenic profile of intestinal mucosal immunity in the high-fat diet/streptozotocin-induced animal model of type 2 diabetes LIV Reunião Anual da Sociedade Portuguesa de Farmacologia/XLII Reunião de Farmacologia Clínica/XXIII Reunião de Toxicologia
Faculdade de Ciências Médicas-Universidade NOVA de Lisboa (Lisboa, Portugal)
2023/12/05 HaPILLness, an animal friendly oral dosing tool Inovac¸a~o@UC 2023
Universidade de Combra (Coimbra, Portugal)
2023/12/04 Innovation & Entrepreneurship Forum EIT Health Ageing PhD School
Universidade de Combra (Coimbra, Portugal)
2023/11/29 HaPILLness: (Re)defining oral dosing in experimental animals INV Seminar @iCBR
Instituto de Investigação Clínica e Biomédica da Faculdade de Medicina da Universidade de Coimbra (Coimbra, Portugal)
2023/11/18 Blueberry Leaves Biomass: A Prebiotic With Gut Immunomodulatory Potential In Type 2 Diabetes Farm to Fork
Centro de Apoio Tecnológico Agro Alimentar (CATAA) (Castelo Branco, Portugal)
2023/11/18 Blueberry Leaves-Based Nutraceutical Improves Gut Immune Balance and Central Impairments In Experimental Multiple Sclerosis Farm to Fork
Centro de Apoio Tecnológico Agro Alimentar (CATAA) (Castelo Branco, Portugal)
2023/10/25 Releaf – upcycling blueberry agrowaste into next-gen prebiotics with immunonutritional value i2A Investiga
Instituto de Investigac¸a~o Aplicada (Coimbra, Portugal)
2023/09/29 HaPILLness - a Lab2Market journey to RDefine animal testing Coimbra Invest Summit 2023
Câmara Municipal de Coimbra em parceria com a Universidade de Coimbra, Instituto Politécnico de Coimbra, Instituto Pedro Nunes e iParque (Coimbra, Portugal)
2023/04/26 Lab2Market: knowledge-based capital for transformative innovation JOB SUMMIT IPC & SCIENCE2BUSINESS
INOPOL - Academia de Empreendedorismo do Polite´cnico de Coimbra (Coimbra, Portugal)
2023/03/27 HAPILLNESS – an animal welfare friendly tool to re(de)fine oral drug dosing in preclinical assays Beyond REMODEL: 3R models for biomedical research
Instituto de Investigação e Inovação em Saúde (i3S) (Porto, Portugal)
2023/02 Blueberry Leaves Biomass: A Nature-Based Functional Ingredient with Hypoglycemic, Hypolipidemic And Gut Immunomodulatory Potential In Type 2 Diabetes LIII Reunião Anual da Sociedade Portuguesa de Farmacologia/XLI Reunião de Farmacologia Clínica/XXII Reunião de Toxicologia
Instituto de Farmacologia e Terapêutica Experimental Faculdade de Medicina da Universidade de Coimbra (Coimbra, Portugal)
2023/02 Metabolic Impact of Long-Term Blueberry Juice Supplementation On A Diet-Induced Rat Model Of Prediabetes LIII Reunião Anual da Sociedade Portuguesa de Farmacologia/XLI Reunião de Farmacologia Clínica/XXII Reunião de Toxicologia
Instituto de Farmacologia e Terapêutica Experimental Faculdade de Medicina da Universidade de Coimbra (Coimbra, Portugal)
2023/02 1,8-Cineole Improves Right Ventricle Dysfunction And Reduces Pulmonary Vascuar Remodeling Associated With Pulmonary Arterial Hypertension LIII Reunião Anual da Sociedade Portuguesa de Farmacologia/XLI Reunião de Farmacologia Clínica/XXII Reunião de Toxicologia
Instituto de Farmacologia e Terapêutica Experimental Faculdade de Medicina da Universidade de Coimbra (Coimbra, Portugal)
2023/02 Fluorescent-Based Bodipy 493/503 Analysis Of Lipid Droplets – Insights For Hepatic Steatosis Assessment LIII Reunião Anual da Sociedade Portuguesa de Farmacologia/XLI Reunião de Farmacologia Clínica/XXII Reunião de Toxicologia
Instituto de Farmacologia e Terapêutica Experimental Faculdade de Medicina da Universidade de Coimbra (Coimbra, Portugal)
2023/02 Pill Tech – Re(De)Fining Oral Dosing In In Vivo Preclinical Assays LIII Reunião Anual da Sociedade Portuguesa de Farmacologia/XLI Reunião de Farmacologia Clínica/XXII Reunião de Toxicologia
Instituto de Farmacologia e Terapêutica Experimental Faculdade de Medicina da Universidade de Coimbra (Coimbra, Portugal)
2023/02 Pro-Inflammatory Cues Towards Remyelination: Novelty Effects Of A Blueberry Leaves-Based Nutraceutical LIII Reunião Anual da Sociedade Portuguesa de Farmacologia/XLI Reunião de Farmacologia Clínica/XXII Reunião de Toxicologia
Instituto de Farmacologia e Terapêutica Experimental Faculdade de Medicina da Universidade de Coimbra (Coimbra, Portugal)
2023/02 An Experimental Study Using The Cuprizone-Induced Mouse Model Of Multiple Sclerosis LIII Reunião Anual da Sociedade Portuguesa de Farmacologia/XLI Reunião de Farmacologia Clínica/XXII Reunião de Toxicologia
Instituto de Farmacologia e Terapêutica Experimental Faculdade de Medicina da Universidade de Coimbra (Coimbra, Portugal)
2022/02/09 Antidyslipidemic Effect of Oleacein in the Apoe-Ko Mice Model of Atherosclerosis LII Reunião Anual da Sociedade Portuguesa de Farmacologia/XL Reunião de Farmacologia Clínica/XXI Reunião de Toxicologia
Instituto de Ciências Biomédicas Abel Salazar (Porto, Portugal)
2021/02/19 Sub-Chronic Toxicity Evaluation of Green Enzyme-Assisted Processing of Senescent Vaccinium Leaves Biomass in Mice LI Meeting of the Portuguese Society for Pharmacology, Lisboa, Portugal
Faculdade de Farmácia da Universidade de Lisboa
2021/02/19 Blueberry Effects on Diet-Induced Prediabetic Nephropathy - An In Vivo Approach LI Meeting of the Portuguese Society for Pharmacology, Lisboa, Portugal
Faculdade de Farmácia da Universidade de Lisboa
2021/02/18 In-Depth Insights of Hepatoprotective Effects of Blueberries in a Hypercaloric Diet-Induced Rat Model of Prediabetes LI Meeting of the Portuguese Society for Pharmacology, Lisboa, Portugal
Faculdade de Farmácia da Universidade de Lisboa
2021/02/18 Refined Food Processing Elicits Harmful Effects on the Kidney - A Preclinical Study LI Meeting of the Portuguese Society for Pharmacology, Lisboa, Portugal
Faculdade de Farmácia da Universidade de Lisboa
2020/02 The sour side of a Blueberry supplementation in health L Meeting of the Portuguese Society for Pharmacology, Coimbra, Portugal
Faculdade de Farmácia, Universidade de Coimbra (Coimbra, Portugal)
2020/02 Renal Effects of Blueberry Juice in a Prediabetic Rat Model Induced by Hypercaloric Diet L Meeting of the Portuguese Society for Pharmacology, Coimbra, Portugal
Faculdade de Farmácia, Universidade de Coimbra
2020/02 A Novel Semi-Solid Vehicle for Voluntary Oral Drug Dosing in Experimental Rodents L Meeting of the Portuguese Society for Pharmacology, Coimbra, Portugal
Faculdade de Farmácia, Universidade de Coimbra
2019/11/06 Invited Speaker - "Refining drugs administration" III Modular training in Laboratory Animal Science – Rodents
iCBR – Faculdade de Medicina da Universidade de Coimbra (Coimbra, Portugal)
2019/02 Circulating extracellular vesicles in methamphetamine- intoxicated mice subjected to chronic aerobic physical exercise SPF Meeting 2019 (XLIX Reunião Anual da Sociedade Portuguesa de Farmacologia/XXXVII Reunião de Farmacologia Clínica/XVIII Reunião de Toxicologia)
(Porto, Portugal)
2019/02 Effects of incretin-based therapies on the gastrointestinal motility of an animal model of multiple sclerosis. SPF Meeting 2019 (XLIX Reunião Anual da Sociedade Portuguesa de Farmacologia/XXXVII Reunião de Farmacologia Clínica/XVIII Reunião de Toxicologia)
(Porto, Portugal)
2019/02 Gut barrier integrity, serum inflammation and liver damage in a rat model of prediabetes induced by hypercaloric diet - Effects of blueberry juice treatment. SPF Meeting 2019 (XLIX Reunião Anual da Sociedade Portuguesa de Farmacologia/XXXVII Reunião de Farmacologia Clínica/XVIII Reunião de Toxicologia)
(Porto, Portugal)
2018/11/15 Invited Speaker - Practical examples of Refinement in an animal facility III Simpósio Nacional de ORBEAs
Universidade de Coimbra Faculdade de Medicina (Coimbra, Portugal)
2018/02 Effects of blueberry juice on the evolution of liver injury in a rat model of diet-induced prediabetes SPF Meeting 2018 (XLVIII Reunião Anual da Sociedade Portuguesa de Farmacologia/XXXVI Reunião de Farmacologia Clínica/XVII Reunião de Toxicologia)
(Lisboa, Portugal)
2018/02 Acute Behavioral, cellular and molecular signature of the new psychoactive substance MDPV in mice SPF Meeting 2018 (XLVIII Reunião Anual da Sociedade Portuguesa de Farmacologia/XXXVI Reunião de Farmacologia Clínica/XVII Reunião de Toxicologia)
Lisboa, Portugal (Lisboa, Portugal)
2017/09 Brain innate immunity kindled by dopaminergic toxicants 53rd Congress of the European Societies of Toxicology (SESSION 3 – SYMPOSIUM Neuroimmune interactions: challenges for hazard identification)
(Bratislava, Slovakia)
2017/09 Parkinson´s disease: Myenteric gliosis in an experimental rat model 29th European Congress of Pathology (OFP-15 Joint-session Neuropathology/Ophtalmic Pathology)
(Amsterdão)
2017/02 The effects of physical exercise on non-motor symptoms and on neuroimmune RAGE-network in experimental parkinsonism XLVII Reunião da Sociedade Portuguesa de Farmacologia
(Coimbra, Portugal)
2016/11/21 Healthy aging, how sweet can it be? The role of glycotoxins in degenerative diseases Mês da Ciência
AE-ESTESC (Coimbra, Portugal)
2016/02 Premotor enteric nervous system impairment in na experimental Parkinson model XLVI Reunião da Sociedade Portuguesa de Farmacologia
(Porto, Portugal)
2016/02 Impaired gut dopaminergic function in an experimental Parkinson rat model XLVI Reunião da Sociedade Portuguesa de Farmacologia
(Porto, Portugal)
2016 RAGEing astrocytes in early Parkinson’s disease XLVI Reunião da Sociedade Portuguesa de Farmacologia
Sociedade Portuguesa de Farmacologia (Porto)
2015/10/23 Poliaminas biogénicas e suas aplicações terapêuticas XIX Encontro Nacional de Licenciados em Farmácia
Associação Portuguesa de Licenciados em Farmácia (Vila Real, Portugal)
2015 Reactive gliosis is not sustained by S100B/RAGE axis in dysfunctional striata from MPTP-intoxicated C57BL/6 mice XLV Reunião da Sociedade Portuguesa de Farmacologia
Nova Medical School (Lisboa, Portugal)
2013/02 Memory deficits in a pre-diabetic rat model XLIII Reunião annual da Sociedade Portuguesa de Farmacologia, Porto
(Porto, Portugal)
2013/02 Treadmill exercise recovers methamphetamine-induced damage to dopaminergic and serotonergic terminals in mice XLIII Reunião annual da Sociedade Portuguesa de Farmacologia
(Porto, Portugal)
2012 The impact of a dopaminergic neurotoxin on striatal RAGE levels IV Annual Meeting of IBILI - “From cell biology to in vivo molecular and functional imaging”
IBILI (Coimbra)
2012 Striatal RAGE down-regulation prior to dopaminergic denervation in a MPTP mouse model of Parkinson’s disease XLII Reunião Anual da Sociedade Portuguesa de Farmacologia
Faculdade de Farmácia Universidade de Lisboa (Lisboa, Portugal)
2012 RAGE down-regulation: an early event in striatal dysfunction in a mouse model of Parkinson’s disease 6th European Congress of Pharmacology
EPHAR (Granada)
2011/12 Methamphetamine neurotoxicity: a tale on striatal glutamatergic/GABAergic homeostasis disruption Global Addiction Bienal Meeting
(Lisboa, Portugal)
2011 Time-dependent effects of methamphetamine on striatal neurochemical and astrocytic profile and motor coordination in mice 3rd International Congress - Drug Abuse Research Society
IDARS (Istanbul , Turkey)
2001/10/21 Nutrição parenteral XV Encontro Nacional de Licenciados em Farmácia
Associação Portuguesa de Licenciados em Farmácia (Braga, Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2023/09 - Current Blueberry-based antioxidant fiber: exploring their nutraceutical aptitude for Multiple Sclerosis symptomatic relief
Supervisor of Beatriz Antunes Rodrigues
 Farmácia - especialização em Farmacoterapia Aplicada (Master)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2023/09 - Current Remyelination potential of sitagliptin DPP-4 inhibitor in Multiple Sclerosis: a preclinical approach
Supervisor of Renan Colombo de Castro
 Farmácia - especialização em Farmacoterapia Aplicada
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2023/09 - Current Drug-Food Interactions of Lipid-Lowering Statin Drugs and Mediterranean-based Dietary Supplements: Friends or Foes?
Supervisor of Rita Rafaela Galinha Costa
 Farmácia - especialização em Farmacoterapia Aplicada (Master)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2023/09 - Current Flavonoids-AhR pharmacodynamics in the gut-immune-kidney axis: Therapeutic insights in Chronic Kidney Disease
Supervisor of Sara Rodrigues Martins
 Farmácia - especialização em Farmacoterapia Aplicada
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2023/09 - Current Remyelination potential of sitagliptin, a DPP-4 inhibitor, in Multiple Sclerosis: a preclinical approach
Supervisor of Pedro Silva
 Farmácia - especialização em Farmacoterapia Aplicada (Master)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2022/07 - Current Bioconversion of blueberry-based agrowastes into functional ingredients with improved immunonutritional value in Chronic Kidney Disease
Supervisor of Pedro Miguel Dias Vieira
 Ciências da Saúde (PhD)
Universidade de Coimbra Faculdade de Medicina, Portugal
2021/07 - Current Blueberry leaf biomass: a nutraceutical for Multiple Sclerosis’ relief by targeting the gut-immune-CNS axis
Supervisor of Carolina Ferreira
 Ciências da Saúde (PhD)
Universidade de Coimbra Faculdade de Medicina, Portugal
2020/09 - Current A voluntary semi-solid PILL approach for rodent drug dosing - 3R's in motion
Supervisor of Inês Mendes Preguiça
 Ciências da Saúde (PhD)
Universidade de Coimbra Faculdade de Medicina, Portugal
2020/09 - Current Beneficial effects of Faecalibacterium prausnitzii and Akkermansia muciniphila delivery systems in inflammatory bowel disease and prediabetes rodent models
Co-supervisor of André Filipe Baltazar Alves
 Ciências da Saúde (PhD)
Universidade de Coimbra Faculdade de Medicina, Portugal
2021/07 - 2022/11 Preclinical evaluation of the therapeutic potential of Sitagliptin in experimental Multiple Sclerosis
Supervisor
 Biotecnologia Farmacêutica (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2021/09 - 2022/09 Gut-immune-CNS axis modulation in Multiple Sclerosis: An update
Supervisor of Carlota Luís
 Farmácia (Degree)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2021/09 - 2022/09 Prebiotics, probiotics, synbiotics and postbiotics: An update
Supervisor of Rasha Kanan
 Farmácia (Degree)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2021/09 - 2022/09 Gut-Liver-Kidney axis in diabetic kidney disease: An update
Supervisor of Ana Daniela Cruz
 Farmácia (Degree)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2021/09 - 2022/09 Dietary fiber, resistant starch and polyphenols: new functional ingredients from old matrices
Supervisor of Francisco Teixeira
 Farmácia (Degree)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2021/09 - 2022/09 Plant by-products as a source of bioactives compounds: a review
Supervisor of David Wu
 Farmácia - especialização em Farmacoterapia Aplicada (Master)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2019/09 - 2022/06 Effects of the oral antidiabetic sitagliptin on thymic T-cell subsets of an animal model of multiple sclerosis
Supervisor of Patrícia Couceiro
 Farmácia - especialização em Farmacoterapia Aplicada (Master)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2020/09 - 2021/10 Preclinical evaluation of the therapeutic potential of Vaccinium corymbosum L. (blueberry) leaf biomass in experimental Multiple Sclerosis
Supervisor of Ana Carolina Marques Ferreira
 Investigação Biomédica (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2020/09 - 2021/10 Anti-atherogenic properties of oleacein in an animal model - an experimental study
Co-supervisor of Beatriz Maria Lemos Ormonde
 Bioquímica (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2020/08 - 2021/07 O Potencial Terapêutico do Uso de Prebióticos, Probióticos e Simbióticos na Doença Inflamatória Intestinal
Supervisor of Ana Rita Brandão Silva
 Farmácia (Degree)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2020/08 - 2021/07 Metabolic Changes Underlying the Pathophysiology of Multiple Sclerosis - New Therapeutic Opportunities
Supervisor of Ana Cerveira
 Farmácia (Degree)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2020/08 - 2021/07 The Gut-Brain Axis on Multiple Sclerosis Pathophysiology-New Therapeutic Opportunities
Supervisor of Miguel de Campos e Silva
 Farmácia (Degree)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2020/08 - 2021/07 The Role of Polyphenols in Chronic Kdney Disease
Supervisor of Carolina Matias Bernardes
 Farmácia (Degree)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2019/09 - 2020/12/17 Blueberries Effects on Diet-Induced Prediabetic Nephropathy - an In Vivo Experimental Approach
Supervisor of Pedro Miguel Dias Vieira
 Química Medicinal (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2019/09 - 2020/09 A retrospective study of warfarin adverse reactions in St Luis-MA Hospital, Brasil
Supervisor of Mariana Ayres
 Farmácia - especialização em Farmacoterapia Aplicada (Master)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2019/09 - 2020/09 Potential drug interactions in hospital prescriptions in St Luis-MA Hospital, Brasil
Supervisor of Luciana Abreu Freitas
 Farmácia - especialização em Farmacoterapia Aplicada (Master)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2019/09 - 2020/06 Strategies for blueberry leaves biomass enrichment in polyphenols heterosides towards neuroprotection in experimental multiple sclerosis
Supervisor of Rita Gonçalves
 Farmácia (Degree)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2019/09 - 2020/06 Cannabis-derived bioactives - Therapeutic implications for Multiple Sclerosis
Supervisor of Cristina Matos
 Farmácia (Degree)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2019/09 - 2020/05 Impact of hypercaloric modified diets in overall rodents metabolism
Supervisor of Carolina Almeida
 Farmácia (Degree)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2018/09 - 2020/03 Assessment of benefits and risks of sodium-glucose co-transporter 2 inhibitors in metabolic complications
Supervisor of Ricardo Oliveira
 Farmácia - especialização em Farmacoterapia Aplicada (Master)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2018/09 - 2020/02 Renal effects of blueberry juice in a prediabetic rat model induced by hypercaloric diet
Co-supervisor of Adelaide Catarina Campos Barbosa
 Investigação Biomédica (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2019 - 2020 Brain tissue processing for myelin scoring-an update
Supervisor of Natacha Silveira
 Farmácia (Degree)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2018 - 2019 Optimization of sitagliptin chemical stability profile in a new semi-solid vehicle for preclinical drug research
Supervisor of Ana Filipa Rodrigues Gonçalves
 Farmácia (Degree)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2018 - 2019 Additives screening to enhance chemical stability of a new semi-solid vehicle for preclinical drug research
Supervisor of Inês Ferreira Gomes
 Farmácia (Degree)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2018 - 2019 The Role of Phenolic Compounds in the mitigation of neurodegenerative disorders
Supervisor of Cláudia Sofia Neves Fernandes
 Farmácia (Degree)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2017/09 - 2018/12 The impact of physical exercise on circulation extracellular vesicles in methamphetamine-intoxicated mice
Co-supervisor of Mariana Filipa Gonçalves Madeira Rodrigues
 Biologia Molecular e Celular (Master)
Universidade de Aveiro Departamento de Biologia, Portugal
2017 - 2018 Stability profile of Gliclazide in a new oral semi-solid matrix
Supervisor of João Maria Cerveira de Carvalho Santos
 Farmácia (Degree)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2017 - 2018 Stability profile of Metformin in a new oral semi-solid matrix
Supervisor of Karina Garcia
 Farmácia (Degree)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2016 - 2017 Pleiotropic actions of metabolic drug agents: is RAGE the key
Supervisor of Andreia Leite
 Farmácia (Degree)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2016 - 2017 The potential of phenolic compounds in cancer disease
Supervisor of Sylvie Pina
 Farmácia (Degree)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2013 - 2014 Prediction of biological activity of selected antitumor drugs on the basis retention data obtained with the use of different HPLC columns and QSRR and QSAR strategy
Supervisor of Mónica Varela
 Farmácia (Degree)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2011 - 2012 Characterization if striatal RAGE levels following acute methamphetamine intoxication
Supervisor of Tiago Luís Pires Adriano
 Farmácia (Degree)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2010 - 2011 Alzheimer’s disease: the new type III Diabetes
Supervisor of Luzia Cláudia Mendes da Costa
 Farmácia (Degree)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2009 - 2010 Antiretroviric drug resistance of CCRX/CXCR4 co-receptors inhibitors
Supervisor of Cristiana Correia Oliveira
 Farmácia (Degree)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2009 - 2010 Synthesis of heparin loaded nanoparticles using polysaccharide chitosan: a new approach for the anticoagulant therapy
Supervisor of Ivy Leivas Santos
 Farmácia (Degree)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2009 - 2010 Tau’s phosphorilation and new Tau-directed therapeutic strategies in Alzheimer’s disease
Supervisor of Rute Mariana Gaspar Roleiro
 Farmácia (Degree)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2008 - 2009 Soya Isoflavones impacto on angiogenesis
Supervisor of Vanessa Sofia Pacheco Santo
 Farmácia (Degree)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2008 - 2009 Genistein e Daidzein quantification in soya isoflavones capsules
Supervisor of Liliana Filipa da Fonseca Afonso
 Farmácia (Degree)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2007 - 2008 Propolis: physico-chemical composition and therapeutic properties
Supervisor of Patricia Alexandra da Rosa Pinheiro
 Farmácia (Degree)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2007 - 2008 Phenolic compounds screening for therapeutic purposes
Supervisor of Ana Teresa Ramos de Sousa Coutinho
 Farmácia (Degree)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2006 - 2007 Therapeutic potential of biogenic polyamines
Supervisor of Andreia Filipa Francisco Pombo
 Farmácia (Degree)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2006 - 2007 Pharmacogenetic and pharmacogenomic
Supervisor of Carla Isabel Azevedo Gomes
 Farmácia (Degree)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2006 - 2007 Imunotherapy: na update
Supervisor of Marta Caldeira Susana
 Farmácia (Degree)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2005 - 2006 New molecular targets for osteoporosis management
Supervisor of Sílvia Raquel Ferreira Fonseca
 Farmácia (Degree)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2005 - 2006 Manual de Segurança para o Laboratório de Química
Supervisor of Susana Cristina Lages de Oliveira
 Farmácia (Degree)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2005 - 2006 Biotechnological drugs – a new era
Supervisor
 Farmácia (Degree)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2004 - Current “Simpósio Farmacovigilância” - Associação Portuguesa de Licenciados em Farmácia, Coimbra (2004/12/14 - 2004/12/14)
Symposium (Member of the Organising Committee)
2023/11/18 - 2023/11/18 Trends moving Pharmacy Forward – Challenges and Opportunities (2023/11/18 - 2023/11/18)
Congress (Member of the Scientific Committee)
 Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2022/10/10 - 2022/10/12 LIII Reunião Anual da Sociedade Portuguesa de Farmacologia/XLI Reunião de Farmacologia Clínica/XXII Reunião de Toxicologia (2022/10/10 - 2022/10/12)
Congress (Member of the Organising Committee)
 Universidade de Coimbra Faculdade de Medicina, Portugal
2021/05 - 2022/05 Annual Meeting 2022 - "A saúde pós-covid" (2022/05/11 - 2022/05/11)
Conference (Member of the Organising Committee)
 Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2021/05 - 2021/07 Microbiota intestinal e severidade da COVID-19 – Influências nutracêuticas (2021/06/12 - 2021/06/12)
Conference (Member of the Organising Committee)
 Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2020/05 - 2020/07 Doenc¸a de Kawasaki e a Covid 19 (2020/06/14 - 2020/06/14)
Conference (Member of the Organising Committee)
 Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2020 - 2020 Annual Meeting 2020-"SAÚDE 4.0: DESENHAR A SAÚDE DE AMANHÃ" (2020/06/25 - 2020/06/27)
Meeting (Member of the Organising Committee)
 Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2019/04/05 - 2019/04/06 Annual Meeting 2019 - "Primary Health Care: Challenges and Opportunities" (2019/04/05 - 2019/04/06)
Meeting
2010/04/24 - 2010/04/24 "I Jornadas do Departamento de Farmácia – Farmácia comunitária, aconselhamento e prestação de cuidados de saúde” ESTESC/IPC, Coimbra (24 Abril 2010) (2010/04/24 - 2010/04/24)
Congress (Member of the Organising Committee)
 Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2008/05/24 - 2008/05/25 VI Congresso Nacional da Associação Portuguesa de Licenciados em Farmácia”, Porto (2008/05/24 - 2008/05/25)
Congress (Member of the Scientific Committee)
2004/11/13 - 2004/11/13 “I European Meeting of Pharmacy Technicians”, promovido pela ANTEF em Lisboa (2004/11/13 - 2004/11/13)
Congress (Member of the Organising Committee)
2004/05/29 - 2004/05/29 “IV Congresso Nacional da Associação Nacional de Licenciados em Farmácia”, Castelo Branco (2004/05/29 - 2004/05/30)
Congress (Member of the Organising Committee)
2004/05/28 - 2004/05/28 “I Encontro Nacional de Estudantes de Farmácia” - Associação Portuguesa de Licenciados em Farmácia, Castelo Branco (2004/05/28 - 2004/05/28)
Meeting (Member of the Organising Committee)

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2004/10 - Current SPSS - Análise estatística dados em saúde
Congress
Instituto para a Inovação na Formação, Portugal
2021/02/17 - 2021/02/19 LI Annual Meeting of the Portuguese Society of Pharmacology, XXXIX Meeting of Clinical Pharmacology and XX Toxicology Meeting
Universidade de Lisboa Faculdade de Farmácia, Portugal
2020/02/05 - 2020/02/07 L Annual Meeting of the Portuguese Society of Pharmacology, XXXVIII Meeting of Clinical Pharmacology and XIX Toxicology Meeting
Congress
Universidade de Coimbra Faculdade de Farmácia, Portugal
2019/11 - 2019/11 III Modular Training in Laboratory Animal Science Modules- Special Skills
Congress
Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia, Portugal
2019/02/06 - 2019/02/08 XLIV Annual Meeting of the Portuguese Society of Pharmacology/XXXVII Meeting of Clinical Pharmacology/XVIII Meeting of Toxicology
Congress
Universidade do Porto Faculdade de Farmácia, Portugal
2019 - 2019 Inovação em Análise e Dispersão de Partículas - L.U.M. GmbH
Congress
Instituto Politécnico de Coimbra, Portugal
2018/11/15 - 2018/11/15 Participation in "III National Symposium of Organs Responsible for the Welfare of Animals (ORBEA)"- "The 3Rs in action, from theory to practice!"
CNC.IBILI, Portugal
2018/03/02 - 2018/03/02 Participation in "VIII Workshop “Dermofarmácia, cosmética e produtos de saúde”
Workshop
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2018/02/05 - 2018/02/07 Participation in "XLVIII Reunião da Sociedade Portuguesa de Farmacologia"
Congress
Universidade de Lisboa Faculdade de Medicina, Portugal
2017/11/28 - 2017/11/28 5º Congresso Regional Envelhecimento Ativo e Saudável (Ageing@Coimbra)
2017/11/03 - 2017/11/04 VII Encontro Nacional de Produtores de Mirtilo – Cooperativa Agro-pecuária dos Agricultores de Mangualde (COAPE)
2017/10/27 - 2017/10/28 Participation in XXV Congresso da Sociedade Portuguesa de Aterosclerose
2017/02/17 - 2017/02/17 Participation in VI Workshop “Dermofarmácia, cosmética e produtos de saúde”
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2017/02/02 - 2017/02/04 Participation in "XLVII Reunião da Sociedade Portuguesa de Farmacologia"
Congress
Universidade de Coimbra Faculdade de Medicina, Portugal
2017 - 2017 III Quantitative Fluorescence Microscopy Course
Congress
Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia, Portugal
2016/11/21 - 2016/11/21 Participation in Seminário “Healthy aging, how sweet can it be? The role of glycotoxins in degenerative diseases.” Mês da Ciência, AE-ESTESC
Seminar
2016/02/04 - 2016/02/06 Participation in XLVI Reunião da Sociedade Portuguesa de Farmacologia (SPF)
Congress
Universidade de Coimbra Faculdade de Medicina, Portugal
2015/12/03 - 2015/12/04 Participation in VII Annual Meeting of IBILI “New trends in biomedical research”
CNC.IBILI, Portugal
2015/09/12 - 2015/09/12 Participation in 51th Congress of the European Societies of Toxicology (Eurotox 2015)
Congress
2015/02/05 - 2015/02/06 Participation in XLV Reunião da Sociedade Portuguesa de Farmacologia, Nova Medical School
Congress
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2014/12/19 - 2014/12/20 Participation in XVIII Congresso da Sociedade Portuguesa de Bioquímica, Coimbra
Congress
2014/12/17 - 2014/12/17 Participation in 5th PF2MUC Symposium “Zoom in Microglia”, Faculty of Medicine, University of Coimbra (17 Dezembro 2014)
Universidade de Coimbra Faculdade de Medicina, Portugal
2014/12/11 - 2014/12/12 Participation in 6th Annual meeting of IBILI
Congress
Universidade de Coimbra Faculdade de Medicina, Portugal
2014/04/06 - 2014/04/06 Participation in 2nd Annual Meeting- Coimbra Health School
Congress
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2014 - 2014 Curso de formação em microscopia de fluorescência e microscopia confocal
Congress
Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia, Portugal
2012/12/06 - 2012/12/07 Participation in IV Annual Meeting of IBILI “From cell biology to in vivo molecular and functional imaging"
Congress
Universidade de Coimbra, Portugal
2012/10/26 - 2012/10/26 Participation in 2nd PF2MUC Symposium Changing paradigms of science
Symposium
Universidade de Coimbra, Portugal
2012/07/17 - 2012/07/20 Participation in 6th European Congress of Pharmacology, Federation of European Pharmacological Societies (EPHAR), Granada, Spain
Congress
2012/02/01 - 2012/02/03 Participation in XLII Reunião Anual da Sociedade Portuguesa de Farmacologia (SPF)
Congress
Universidade de Lisboa Faculdade de Farmácia, Portugal
2012 - 2012 Laboratory Animal Science FELASA Category C
Congress
Universidade do Porto, Portugal
2011/12/06 - 2011/12/07 Participation in 3rd Annual Meeting of IBILI
Congress
Universidade de Coimbra, Portugal
2010/06/05 - 2010/06/06 Participation in VII Congresso Nacional da Associação Portuguesa de Licenciados em Farmácia, Lisboa
Congress
2010/04/24 - 2010/04/24 Participation in I Jornadas do Departamento de Farmácia – Farmácia comunitária, aconselhamento e prestação de cuidados de saúde
Congress
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2008/05/24 - 2008/05/25 Participation in 6º Congresso Nacional da Associação Portuguesa de Licenciados em Farmácia, Porto
Congress
2007/11/17 - 2007/11/17 Participation in 1º Colóquio do Departamento das Ciências Laboratorias Aplicadas na Saúde
Conference
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2007/02/22 - 2007/02/22 Participation in Seminário “Novas metodologias pedagógicas no ensino”
Seminar
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2006/03/12 - 2006/03/12 Participation in V Congresso Nacional da Associação Portuguesa de Licenciados em Farmácia, Lisboa
Congress
2005/10/23 - 2005/10/23 Participation in XIX Encontro Nacional dos Licenciados em Farmácia
Hospital São Pedro de Vila Real, Portugal
2005/05/17 - 2005/05/17 Participation in 2º Congresso das Ciências e Tecnologias da Saúde, Sindicato das Ciências e Tecnologias da Saúde
Congress
Hospitais da Universidade de Coimbra, Portugal
2005/05/02 - 2005/05/02 Participation in II Colóquio de Estudantes de Farmácia
Conference
Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2004/12/14 - 2004/12/14 Participation in Simpósio Farmacovigilância, Associação Portuguesa de Licenciados em Farmácia, Coimbra
Symposium
2004/11/13 - 2004/11/13 Participation in I European Meeting of Pharmacy Technicians, Lisboa
Congress
2004/05/29 - 2004/05/30 Participation in IV Congresso Nacional da Associação Nacional de Licenciados em Farmácia, Castelo Branco
Congress
2004/05/28 - 2004/05/28 I Encontro Nacional de Estudantes de Farmácia, Associação Portuguesa de Licenciados em Farmácia, Castelo Branco
Meeting
2004 - 2004 Sistema de gestão da qualidade: construção base documental
Congress
Centro Hospitalar e Universitário de Coimbra EPE, Portugal
2003/12 - 2003/12 O aprovisionamento na Gestão em Saúde
Congress
Instituto para a Inovação na Formação, Portugal
2003/11 - 2003/11 Terapêutica de suporte em Oncologia II
Congress
Instituto para a Inovação na Formação, Portugal
2003/10/04 - 2003/10/04 XVII Encontro Nacional dos Licenciados em Farmácia, Delegação regional do Instituto Português da Juventude, Lisboa
Meeting
2003/05/24 - 2003/05/25 Participation in III Congresso Nacional da Associação Portuguesa de Licenciados em Farmácia, Aveiro
Congress
2003 - 2003 Curso de formação pedagógica para monitores de estágio das Tecnologias da Saúde
Congress
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2002/12 - 2002/12 Farmacologia aplicada
Other
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2002/07/15 - 2002/07/16 Participation in II Congresso Nacional da Associação Portuguesa de Licenciados em Farmácia, Coimbra
Congress
2002/06 - 2002/06 Medicamentos biotecnológicos
Other
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2001/10/20 - 2001/10/20 Participation in XV Encontro Nacional dos Licenciados em Farmácia
Meeting
Hospital de Braga, Portugal
2001/06/23 - 2001/06/24 Participation in I Congresso Nacional da Associação Portuguesa de Licenciados em Farmácia, Figueira da Foz
Congress
2001/01 - 2001/01 Actualizações em Oncologia
Other
Universidade de Coimbra Faculdade de Medicina, Portugal

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2023/07/21 Potencializac¸ão dos riscos em pacientes diabe´ticos infetados pelo Sars-CoV-2
President of the jury
 Yara Barros dos Reis (Master)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2023/01/26 Contracetivos hormonais orais e a importa^ncia da farmacovigila^ncia
President of the jury
 Ana Luísa Maravilha Cardoso (Master)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2021/10 Preclinical evaluation of the therapeutic potential of Vaccinium corymbosum L. (blueberry) leaf biomass in experimental Multiple Sclerosis
Supervisor
 Ana Carolina Marques Ferreira (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2021/10 Esclerose Múltipla: Mecanismos Fisiopatológicos e Fármacos Modificadores da Doen a
(Thesis) Arguer
 Tiago Filipe Marques Gonçalves (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2021/07 Smart delivering and drug targeting to treat fibrosis in age-related macular degeneration
(Thesis) Main arguer
 Joana Filipa Figueiredo Simão (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2021/07 Propriedades antiaterogénicas de polifenóis de oliveira e do azeite – Estudo experimental em modelo animal
(Thesis) Arguer
 Mariana Santos (Other)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2020/12 Blueberries Effects on Diet-Induced Prediabetic Nephropathy – an In Vivo Experimental Approach
Supervisor
 Pedro Miguel Dias Vieira (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2016 Kalanchoe pinnata: estudo da planta e das suas propriedades farmacológicas e terapêuticas
(Thesis) Main arguer
 João Miguel Francisco Coelho (Other)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2015 Estabilidade do creme de hidroquinona a 5% sujeito a diferentes antioxidantes
(Thesis) Main arguer
 Jessica Sousa da Cruz (Other)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2011 Processo/Procedimento de produção de Microparticulas e Nanoparticulas para encapsulação de medicamentos/Tenofovir
(Thesis) Main arguer
 Carolina de Alexandre Coelho (Other)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2011 Avaliar do impacto das Vitaminas B, C e E na diminuição da taxa de progressão da doença de Alzheimer
(Thesis) Main arguer
 Cíntia Alexandra Moreira Galas (Other)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2011 Medicamentos biotecnológicos no tratamento do cancro da mama
(Thesis) Main arguer
 Ana Rita Lopes de Jesus (Other)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2011 The influence of the graduation in pharmacy in self-medication: students’ knowledge, behavior and attitudes
(Thesis) Main arguer
 João Pedro da Cunha Torres Vieira (Other)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2010 Sistemas de Libertação Controlada: Microemulsões, Lipossomas e Nanopartículas
(Thesis) Main arguer
 Marcelo Soares Coutinho (Other)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2010 Interacções entre Hipericão e medicamentos convencionais
(Thesis) Main arguer
 Alexandra Isabel Rodrigues Santos (Other)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2010 Caracterização de Biomarcadores para o pé Diabético
(Thesis) Main arguer
 Tânia Margarida da Costa Batista (Other)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2008 Os Desreguladores Endócrinos e o seu Impacto no Ambiente: Hormonas Sexuais
(Thesis) Main arguer
 Sylvia Rodrigues da Costa Leonardo (Other)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2008 Abordagem terapêutica da Psoríase
(Thesis) Main arguer
 Sónia Margarida dos Santos Ribeiro (Other)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2008 Terapia Génica e Biológica no Tratamento do Cancro
(Thesis) Main arguer
 Natacha Cordeiro Silveira (Other)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2008 Medicamentos Essenciais
(Thesis) Main arguer
 Daniela Mota da Silva (Other)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2007 Nutrição Parenteral: Estabilidade e Compatibilidade
(Thesis) Main arguer
 Nilton Raposo Melo (Other)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2007 Crenças e Atitudes dos profissionais de Farmácia relativamente aos medicamentos de Biotecnologia
(Thesis) Main arguer
 Vânia Cristina da Silva Saraiva (Other)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2006 Contracepção Oral-Nível de Conhecimento e Métodos utilizados pelas alunas da ESTESC
(Thesis) Main arguer
 Joana Filipa Loureiro Lucas (Other)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2006 Menopausa e Terapia Hormonal de Substituição
(Thesis) Main arguer
 Mónica Sofia Frias Santos (Other)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2006 A doença de Alzheimer e sua Terapêutica
(Thesis) Main arguer
 Marisa Cristina Gonçalves da Silva (Other)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2006 Medição de IMC numa população
(Thesis) Main arguer
 Carina Sofia Jorge Pereira (Other)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal

Association member

Society Organization name Role
2020 - Current Portuguese Society of Laboratory Animal Sciences Member
2018 - Current Portuguese Society of Diabetology
2016/02 - Current Portuguese Society of Pharmacology
2014/11 - Current Portuguese Society of Biochemistry

Conference scientific committee

Conference name Conference host
2019/12/20 - 2019/12/20 Chair Sessão III – Metabolism, Ageing and Disease; CIBB meeting Coimbra
2014/04/06 - 2014/04/06 “Neurodegenerative diseases: what to expect?”: Impacto do medicamento na Saúde publica: novas abordagens - 2nd Annual Meeting - Moderadora Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2010/06/05 - 2010/06/06 “Unidose em Farmácia – o impacto económico e terapêutico”, VII Congresso Nacional da Associação Portuguesa de Licenciados em Farmácia” - Moderadora Lisboa, Portugal
2010/04/24 - 2010/04/24 “Dermofarmácia e cosmética – envelhecimento”, I Jornadas do Departamento de Farmácia - Moderadora
2006/03/12 - 2006/03/12 “Empregabilidade em Farmácia – Mercado do futuro” V Congresso Nacional da Associação Portuguesa de Licenciados em Farmácia – Moderadora Lisboa, Portugal
2005/04/02 - 2005/04/02 “A Farmácia e a Comunidade: Algumas realidades” integrando o painel “O Processo de Bolonha – implicações para o exercício” II Colóquio de Farmácia na Escola Superior Tecnologia de Saúde do Porto - Moderadora Porto, Portugal

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2017 - Current Farmacocinética Clínica Farmácia - especialização em Farmacoterapia Aplicada (Mestrado) Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2017 - Current Informação do Medicamento e Produção Científica Farmácia - especialização em Farmacoterapia Aplicada (Mestrado) Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2008 - Current Farmacologia I Farmácia (Licenciatura) Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2008 - Current Farmacologia II Farmácia (Licenciatura) Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2004/11 - Current Farmacognosia Farmácia (Licenciatura) Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2004/10 - Current Investigação Aplicada em Farmácia Farmácia (Licenciatura) Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2024/05/17 - 2024/05/24 Hackaton (innovation & entrepreneurship) Start'ship (Postgraduate Certificate) Universidade de Coimbra, Portugal
2023/12/04 - 2023/12/06 Innovation Pan-european Doctoral School in Healthy Living and Active Ageing (Docteur) EIT Health Ageing PhD School, Portugal
2019/04/08 - 2019/04/08 Neurodegenerative disorders course, intitulado: “Remielynation strategies in multiple sclerosis” Biologia Experimental e Biomedicina (Doutoramento) Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2018/04/26 - 2018/04/26 Immunology advanced course, intitulado: “Modulation of receptors for advanced glycation endproducts network in Parkinson's disease” Investigação Biomédica (Mestrado) Universidade de Coimbra Faculdade de Medicina, Portugal
2018/03/21 - 2018/03/21 Unidade Curricular Farrmacologia II, intitulado “Modulation of receptors for advanced glycation endproducts network in Parkinson's disease” Química Medicinal (Licenciatura) Universidade de Coimbra Faculdade de Farmácia, Portugal
2006/10 - 2008/09 Química Orgânica Aplicada Farmácia (Licenciatura) Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2004 - 2008 Técnica Farmacêutica Farmácia (Licenciatura) Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal

Journal scientific committee

Journal title (ISSN) Publisher
2018 - Current Oxidative Medicine and Cellular Longevity (1942-0994) Hindawi Limited
2018 - Current Evidence-based Complementary and Alternative Medicine (1741-4288) Hindawi Limited
2020 - 2020 Revista Portuguesa de Cardiologia (0870-2551) Elsevier
2018 - 2018 Revista Portuguesa de Cardiologia (0870-2551) Elsevier
2018 - 2018 “Sinergias e Cooperação entre a Comunidade e o Ensino Superior” da série “Estratégias de Ensino e Sucesso Académico: Boas Práticas no Ensino Superior” Centro de Inovação e Estudo da Pedagogia no Ensino Superior
2017 - 2018 Molecular Neurobiology (0893-7648) Springer-Verlag
2017 - 2017 Brain Research (0006-8993) Elsevier

Mentoring / Tutoring

Topic Student name
2018 - Current Laboratory supervision of a Master students Alexandre Neto
2017 - Current Laboratory Supervision of a Master thesis Mariana Rodrigues
2019 - 2019 Laboratory supervision of students involved in Programa Research Exchange Michal Remen
2019 - 2019 Laboratory supervision of students involved in Programa Research Exchange Karolina Koch Davidsen
2019 - 2019 Laboratory supervision of a Master students Inês Costa
2018 - 2019 Laboratory supervision of a Master thesis Adelaide Catarina Barbosa
2017 - 2017 Laboratory Supervision of a Master Thesis Mafalda Maria Salvador Campeão
2017 - 2017 Laboratory Supervision of a Master Thesis Luciana Branco Fernandes
2013 - 2013 Laboratory Supervision of a Master thesis Inês Roque Antunes Pita
2013 - 2013 Laboratory Supervision of a Master thesis Ana Filipa Vicente Neves
2013 - 2013 Laboratory Supervision of a Master thesis Sheena Martina Domingues Mendes
2013 - 2013 Laboratory Supervision of a Master thesis Ana Irene Saavedra Mateus Dias
2013 - 2013 Laboratory Supervision of a Master thesis Carlos António Dias da Silva
2012 - 2012 Laboratory Supervision of a Master thesis Edna Filipa Pais Soares
2012 - 2012 Laboratory Supervision of a Master thesis Sara Raquel Ramalho Pereira Nunes
Distinctions

Award

2023 1st place: Fase Regional - 19º Edição Poliempreende
Instituto Politécnico de Coimbra, Portugal
2023 Melhor Poster - Investigação Fundamental do 19.º Congresso Português de Diabetes
Sociedade Portuguesa de Diabetologia, Portugal
2022 Acelera@UC: Programa de Aceleração para Empreendedores
Universidade de Coimbra, Portugal

Instituto Pedro Nunes, Portugal
2022 Best Presentation Awards Biosystems in Toxicology and Pharmacology
2021 "From linear to circular ideas" - Upcycling berries agrowaste towards innovative functional ingredients
2021 EPAA 2021 Refinement prize - "Precise voluntary oral drug dosing in rodents – an innovative 3Rs approach"
2021 Best Poster - Annual Meeting Coimbra Health School - Global Health New Trends
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2021 Best Translational Research
Sociedade Portuguesa de Neurologia, Portugal