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João Reis graduated from Biochemistry by the Faculty of Sciences and Institute of Biomedical Sciences Abel Salazar of the University of Porto, in 2017, after concluding his internship in the Biochemistry and Biophysics Institute of Stockholm University. He also completed his MSc degree in Cell and Molecular Biology by the Faculty of Sciences of the University of Porto, in 2019. During his MSc thesis he also enrolled as a Research Technician Fellow in the project HALVERSITY (financed by the FCT) carried in the Interdisciplinary Center of Marine and Environmental Research (CIIMAR), until January 2020. He then joined the project FattyCyanos (CIIMAR) as a Researcher. Currently he is developing his PhD thesis focused on a new family of cyanobacterial enzymes. Main research interests on Biological sciences with emphasis on Biochemistry and Molecular Biology and has focused his research in natural product discovery and biocatalysis.
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Identification

Personal identification

Full name
João Pedro Alves Rodrigues dos Reis
Date of birth
1996/03/21

Citation names

  • Reis, João P. A.

Author identifiers

Ciência ID
5319-3C87-B8AA
ORCID iD
0000-0002-7769-7470

Email addresses

  • jreisfcup@gmail.com (Professional)
  • jreis@ciimar.up.pt (Professional)

Knowledge fields

  • Natural sciences - Biological Sciences - Biochemistry
  • Natural sciences - Biological Sciences - Molecular Biology
  • Natural sciences - Biological Sciences - Biology
  • Exact Sciences - Chemical Sciences - Organic Chemistry

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Spanish; Castilian Intermediate (B1) Intermediate (B1) Elementary (A2) Upper intermediate (B2)
Education
Degree Classification
2021/01 - 2025/03
Ongoing
 Doctoral Degree in Biomedical Sciences (Doutoramento)
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2017 - 2019/11
Concluded
 Biologia Celular e Molecular (Mestrado)
Universidade do Porto Faculdade de Ciências, Portugal
"A novel biocatalytic esterification involved in the biosynthesis of branched bartolosides" (THESIS/DISSERTATION)
 19
2014 - 2017
Concluded
 Bioquímica (Licenciatura)
Universidade do Porto Faculdade de Ciências, Portugal

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Stockholms Universitet Institutionen för biokemi och biofysik, Sweden
"(1) Expression of recombinant fusion protein SNAP-tag and (2) Optimization of ATP synthase purification protocols" (THESIS/DISSERTATION)
 16
Affiliation

Science

Category
Host institution 		Employer
2020/02/01 - 2021 Researcher (Research) Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2018/11/01 - 2020/01/31 Researcher (Research) Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2018 - 2019 Research Trainee (Research) Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2017 - 2017 Research Trainee (Research) Stockholms Universitet Institutionen för biokemi och biofysik, Sweden
Projects

Grant

Designation Funders
2020 - 2021 FattyCyanos
FattyCyanos/BI-MSc/2019-059
Research Fellow
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2018/11/01 - 2020/01/31 HALVERSITY - Genetic and chemical diversity of a novel halogenase class
PTDC/BIA-BQM/29710/2017
Research Technician Fellow
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal

Other

Designation Funders
2021 - 2024 PROPELLER - INVESTIGATION OF A NEW CLASS OF BETA-PROPELLER ENZYMES
PTDC/BIA-BQM/5760/2020
Team Member
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
Outputs

Publications

Conference poster
  1. Reis, João Pedro Alves; Leão, Pedro N.. Corresponding author: Leão, Pedro N.. "Discovery of novel hydroxylated bartolosides - a biological mechanism perspective". Paper presented in Directing Biosynthesis VII, 2024.
  2. Reis, João Pedro Alves; Leão, Pedro N.. Corresponding author: Leão, Pedro N.. "Exploring bartolosides chemical diversity - a group of cyanobacterial dialkylresorcinols". Paper presented in XIII European Congress on Marine Natural Products and XVII International Symposium on Marine Natural Products, 2023.
  3. Reis, João Pedro Alves; Leão, Pedro N.. Corresponding author: Leão, Pedro N.. "Exploring bartolosides chemical diversity – a group of cyanobacterial dialkylresorcinols". Paper presented in IV Blue Think Conference: Share Science, Spread Knowledge!, 2023.
  4. Amaranta, Kahn; Figueiredo, Sandra; Reis, João Pedro Alves; Vieira Ana Rebelo; Leão, Pedro N.; Marine Cuau; Abt, Kathleen. "Exploring a new pathway of exogenous fatty acid incorporation in cyanobacteria". Paper presented in Curious 2022-Future Insight Conference, 2022.
  5. Reis, João Pedro Alves; Leão, Pedro N.. "Exploring the chemical diversity of bartolosides – a group of cyanobacterial chlorinated dialkylresorcinols". Paper presented in Directing Biosynthesis VI, 2022.
  6. Reis, João Pedro Alves; Leão, Pedro N.. "Exploring the chemical diversity of a group of cyanobacterial chlorinated dialkylresorcinols – the bartolosides". Paper presented in III Blue Think Conference: Share Science, Spread Knowledge!, 2022.
  7. Reis, João Pedro Alves; Leão, Pedro N.. "In silico analysis of a novel family of cyanobacterial alkylating enzymes". Paper presented in XII European Congress on Marine Natural Products, 2021.
  8. Reis, João Pedro Alves; Leão, Pedro N.. "In silico analysis, expression and purification of BrtB, a new C-O bond forming enzyme". Paper presented in II Blue Think Conference: Share Science, Spread Knowledge!, 2021.
  9. Reis, João Pedro Alves; Sandra A. C. Figueiredo; Pedro Nuno Leão. "BrtB is a novel enzyme that catalyzes the O-alkylation of bartolosides with free fatty acids". Paper presented in 11th European Workshop on the Biology of Cyanobacteria, 2020.
  10. Reis, João Pedro Alves; Leão, Pedro N.. "A novel O-alkylating enzyme that esterifies bartolosides with free fatty acids". Paper presented in I Blue Think Conference: Share Science, Spread Knowledge!, 2020.
  11. Reis, João Pedro Alves; Figueiredo, Sandra; Leão, Pedro N.. "A novel enzymatic esterification involved in the biosynthesis of branched bartolosides". Paper presented in XVI International Symposium on Marine Natural Products & XI European Conference on Marine Natural Products, 2019.
  12. Eusebio, Nadia; Reis, João Pedro Alves; Cassell, Samantha; Nakamura, Hitomi; Glasser, Nathaniel; Balskus, Emily; Leão, Pedro N.. "Diversity and distribution of CylC-like enzymes among Cyanobacteria". Paper presented in XVI MaNaPro & XI ECMNP, 2019.
Journal article
  1. Reis, João Pedro Alves; Freitas, Sara; Procházková, Tereza; Leão, Pedro N.. Corresponding author: Leão, Pedro N.. "Expanding the Diversity of the Cyanobacterial Dialkylresorcinol Bartoloside Family". Journal of Natural Products (2024): http://dx.doi.org/10.1021/acs.jnatprod.4c00832.
    10.1021/acs.jnatprod.4c00832
  2. Leão, Pedro N.; Martins, Teresa P.; Abt, Kathleen; Reis, João P. A.; Figueiredo, Sandra; Castelo-Branco, Raquel; Freitas, Sara. "Incorporation and modification of fatty acids in cyanobacterial natural products biosynthesis". Chemical Communications 59 30 (2023): 4436-4446. http://dx.doi.org/10.1039/d3cc00136a.
    10.1039/d3cc00136a
  3. Reis, João P. A.; Figueiredo, Sandra A. C.; Sousa, Maria Lígia; Leão, Pedro N.. "BrtB is an O-alkylating enzyme that generates fatty acid-bartoloside esters". Nature Communications 11 1 (2020): http://dx.doi.org/10.1038/s41467-020-15302-z.
    10.1038/s41467-020-15302-z
Thesis / Dissertation
  1. Reis, João Pedro Alves. "A novel biocatalytic esterification involved in the biosynthesis of branched bartolosides". Master, Universidade do Porto Faculdade de Ciências, 2019.
  2. "Project I: pYM28-SNAP strain construction; Project II: ATP synthase purification". Degree, Universidade do Porto Faculdade de Ciências, 2017.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2024 Discovery of novel hydroxylated bartolosides - a biological mechanism perspective V Blue Think Conference: Share Science, Spread Knowledge!
CIIMAR, University of Porto (Portugal)
2023 Exploring bartolosides chemical diversity – a group of cyanobacterial chlorinated dialkylresorcinols III Meeting PhD in Biomedical Sciences
ICBAS, University of Porto (Portugal)

Mentoring / Tutoring

Topic Student name
2022 - 2022 Expression of novel cyanobacterial enzymes Matea Radešic