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Norberto Cysne Coimbra, formado em Medicina pela Universidade Federal do Espírito Santo (1988), Mestre em Ciências com Distinção e Louvor (Magister Scientiae, cum Laude) (Área de Concentração: Neuropsicobiologia) pela Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto-USP (1991), concluiu o Doutorado em Ciências (Scientiae Doctor) (Área de Concentração: Morfologia-Biologia Celular) na Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo (FMRP-USP) em 1995 (Departamento de Morfologia). Como ex-Docente do Departamento de Morfologia da FMRP-USP (1991-2001), trasladou-se para o Departamento de Farmacologia da FMRP-USP em 28/2/2001. Realizou Pós-doutorado no "Pain Imaging Neuroscience (PaIN) Group of the Department of Physiology, Anatomy & Genetics of the University of Oxford" (denominado "Human Anatomy & Genetics Department" até dezembro de 2005), de 09/01/2006 a 30/06/2006, e no "Centre for Functional Magnetic Resonance Imaging of the Brain (FMRIB) of the Clinical Neurology Department of the University of Oxford (Oxford, England, United Kingdom)", de 01/07/2006 a 08/01/2007. Livre Docente em Neuroanatomia pelo Departamento de Cirurgia e Anatomia da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo (2010), exerceu o cargo de Professor Assistente Doutor na FMRP-USP de 1991 a 1995, foi Professor Doutor na FMRP- USP de 1995 a 2010, exercendo a partir de então a função de Professor Associado da Universidade de São Paulo, onde tem exercido suas atividades no Departamento de Farmacologia da FMRP-USP (desde meados de 2001). Após progressão horizontal na carreira em 2013, tornou-se Professor Associado III na Universidade de São Paulo. Publicou 159 artigos completos em periódicos especializados e 237 resumos em anais de congressos e periódicos científicos. Possui 12 capítulos de livros publicados. É "referee" de diversas revistas especializadas de circulação internacional (Neuropharmacology, Experimental Neurology, Neuroscience, Brain Research, Pain, Basic & Clinical Pharmacology & Toxicology, Anatomy Record, Clinical Anatomy, Journal of the Peripheral Nervous System, Braz. J. Med. Biol. Res., Pharmacology Biochemistry and Behavior, Physiology & Behavior, Nutritional Neuroscience, Progress in Neuro-Psychopharmacology & Biological Psychiatry, Neurocience Letters, Journal of Pain), consultor ad hoc do CNPq, da FAPESP e da CAPES. Participou de vários eventos no exterior e no Brasil. Orientou 27 alunos de mestrado e 22 alunos de doutorado, além de ter orientado 4 alunos de pré-iniciação científica, 66 acadêmicos de iniciação científica (dentre eles, 2 alunos do Trans-Pacific Program & International Federation of Medical Students' Associations Program" e 12 trabalhos de conclusão de curso como Bacharelado e Licenciatura Plena), 7 alunos de aperfeiçoamento científico, e atuado como supervisor de 16 trabalhos de pós-doutorado concluídos, nas áreas de neuropsicofarmacologia, neuroeletroquímica, neuroanatomia e neurofisiologia, e supervisionou 8 alunos PAE. Recebeu 7 prêmios e/ou homenagens. Entre 1995 e 2021 coordenou 17 projetos individuais de pesquisa e um projeto temático (NAP-USP-Neurobiologia das Emoções-NuPNE), sendo que atuou como Pesquisador Principal ou colaborador em outros 5 Projetos Temáticos/Multiusuários. Atua na área de Psiconeurofarmacologia, Neuropsicobiologia e na área de Morfologia-Biologia Celular, com ênfase em Neuroanatomia Descritiva e Aplicada. Em suas atividades profissionais interagiu com cerca de 170 colaboradores em coautorias de trabalhos científicos. É membro Titular da Área de Pós-graduação em Neurologia da FMRP-USP, Membro Titular da Comissão de Ética da FCFRP-USP, das EERP-USP e da FFCLRP-USP, foi Membro Titular do Grupo de Apoio Pedagógico de Ribeirão Preto (GAP-RP-USP), é membro Titular do Conselho do Departamento de Farmacologia e Suplente da Congregação da FMRP-USP. Foi Pesquisador 1A do CNPq (2010-2021); Índice H: 35 (ISI web of science).
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Identification

Personal identification

Full name
Norberto Cysne Coimbra Coimbra

Citation names

  • Coimbra, NC

Author identifiers

Ciência ID
5514-71F2-9A16
ORCID iD
0000-0002-4676-2620

Telephones

Fax
  • (55) 1633153349 (Professional)
Telephone
  • (55) 1633153116 (Professional)

Addresses

  • Avenida Bandeirantes, 3900, FMRP-USP, 14049-900, Ribeirão Preto, Monte Alegre, Brazil (Professional)

Websites

  • https://www.lnn-fmrp-usp.com.br/ (Scholar)

Knowledge fields

  • Medical and Health Sciences - Basic Medicine - Anatomy and mMrphology
  • Medical and Health Sciences - Basic Medicine - Neurosciences
  • Medical and Health Sciences - Basic Medicine - Pharmacology and pharmacy

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Advanced (C1) Proficiency (C2) Proficiency (C2) Upper intermediate (B2) Proficiency (C2)
Latin Beginner (A1) Beginner (A1) Elementary (A2) Beginner (A1)
Education
Degree Classification
1982/01/02 - 1988/09/06
Concluded
 Medicina (Graduado)
Major in Clínico Geral
Universidade Federal do Espírito Santo, Brazil
"Identificação de Neurônios Opioides e Serotoninérgicos do Teto Mesencefálico e seu Papel na Analgesia Induzida por Estimulação Intracerebral Aversiva" (THESIS/DISSERTATION)
Affiliation

Teaching in Higher Education

Category
Host institution 		Employer
2010/04/13 - Current Associate Professor (University Teacher) Universidade de São Paulo, Brazil
Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo, Brazil
1991/10/14 - 2010/04/12 Assistant Professor (University Teacher) Universidade de São Paulo, Brazil
Universidade de São Paulo Faculdade de Medicina de Ribeirão Preto, Brazil
Projects

Grant

Designation Funders
2016/03/01 - 2022/02/28 Estudo do Envolvimento de Receptores Opioides do tipo µ e ¿, e de receptores Endocanabinoides CB1 e CB2 da Substância Negra, Parte Reticulada, na Modulação da Atividade da Via GABAérgica Nigro-tectal durante a Organização do Comportamento de Defesa Eliciado por Camundongos Confrontados com Serpentes
Eur Neuropsychopharmacol. 2016 Mar;26(3):532-45
Brain Res Bull. 2016 Oct;127:74-83
Neuroscience 2016 Nov 12;336:133-145
Neuroscience 2016 Nov 19;337:17-26
Synapse 2016 Dec;70(12):519-530
Behav Brain Res. 2017 Jan 1;316:294-304
Neuropharmacology 2017 Feb;113(Pt A):156-166
Neuropharmacology 2017 Feb;113(Pt A):367-385
Behav Brain Res. 2017 Feb 15;319:135-147
Braz J Psychiatry 2017 Jan-Mar;39(1):72-83
Neuroscience 2017 Jun 23;354:178-195
J Psychopharmacol. 2017 Jun;31(6):715-721
Psychopharmacology (Berl). 2017 Oct;234(20):3009-3025
Eur Neuropsychopharmacol. 2017 Nov;27(11):1120-1131
Neuroscience 2018 Jan 15;369:336-349
Front Neural Circuits. 2018 May 7;12:36
J Psychopharmacol. 2018 Jun;32(6):711-722
Neuroscience 2018 Jul 15;383:191-204
Physiol Behav. 2018 Oct 1;194:162-169
Physiol Behav. 2018 Oct 1;194:538-544
Physiol Behav. 2018 Nov 1;196:104-111
Behav Brain Res. 2019 Jan 14;357-358:71-81
J Psychopharmacol. 2019 Jan;33(1):51-61
J Neurosurg. 2019 April; 130 (4): 1210-1223
Rev Neurosci. 2019 Apr 24;30(3):325-337
J Psychopharmacol. 2019 May;33(5):577-588
Psychopharmacology (Berl). 2019 Jun;236(6):1863-1874
Eur Neuropsychopharmacol. 2019 Jul;29(7):858-870
Neurochem Res. 2019 Sep;44(9):2068-2080
J Psychopharmacol. 2019 Dec;33(12):1524-1532
Neuropsychobiology. 2019;78(4):218-228
J Neurosci Res. 2020 Feb;98(2):338-352
Neurosci Biobehav Rev. 2020 Feb 22;112:363-373
Research Fellow
Conselho Nacional de Desenvolvimento Científico e Tecnológico, Brazil

Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto da Universidade de São Paulo, Brazil
Ongoing
2011/03/01 - 2016/02/29 Estudo do Envolvimento do Sistema Opióide, Serotoninérgico e Noradrenérgico do Sistema Endógeno de Inibição de Dor em Processos Antinociceptivos Induzidos por Reações de Fuga Orientada Evocada pela Estimulação Química do Hipotálamo Medial
Nanomedicine: Nanotechnology, Biology , and Medicine, 7: 871-880, 2011
Epilepsy & Behavior, 22: 165-177, 2011
Epilepsy & Behavior, 22: 178-185, 2011
Neuropeptides, 46: 39-47, 2012
Neuropsychopharmacology, 37: 412-421, 2012
/ Journal of the Neurological Sciences, 312: 73-78, 2012
Pharmacology, Biochemistry & Behavior, 101: 265-270, 2012
Brazilian Journal of Medical and Biological Research, 45:328-336, 2012
Behavioural Brain Research, 233: 422-427, 2012
Pflugers Arch.-European Journal of Physiology, 464: 155-166, 2012
Neuroscience 2012 Dec 27;227:350-60
Neuropharmacology 2013 Apr;67:379-94
Neurosci Lett. 2013 Feb 22;535:116-21
Cereb Cortex. 2014 Jun;24(6):1518-28
Eur J Pharmacol. 2013 Jan 5;698(1-3):235-45
Int J Radiat Biol. 2013 Aug;89(8):595-601
Int J Neuropsychopharmacol. 2013 Sep;16(8):1781-98
J Psychopharmacol. 2013 Dec;27(12):1141-8
Brain Behav. 2013 May;3(3):286-301
Synapse 2014 Jan;68(1):16-30
J Psychopharmacol. 2013 Dec;27(12):1149-59
Synapse 2014 Aug;68(8):369-77
Brain Res. 2014 Aug 12;1576:35-42
J Neurol Sci. 2014 Dec 15;347(1-2):82-9
Neuroscience 2015 Jan 22;284:988-97
Brain Res. 2015 Feb 9;1597:168-79
Synapse 2015 Jun;69(6):299-313
Eur J Pharmacol. 2015 Jul 5;758:153-63
Neuroscience 2015 Sep 10;303:503-14
Behav Brain Res. 2015 Oct 15;293:143-52
Neuropharmacology 2015 Dec;99:620-6
Brain Res. 2016 Jan 15;1631:80-91
/ Behav Brain Res. 2016 Feb 1;298(Pt B):65-77
Other
Universidade de São Paulo Faculdade de Medicina de Ribeirão Preto, Brazil

Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto da Universidade de São Paulo, Brazil
Conselho Nacional de Desenvolvimento Científico e Tecnológico
Concluded
2006/01/01 - 2006/12/31 Mental Representation of the Emotional Behavior of Defensive Attention Oriented to Aversive Stimuli and Fear-induced Analgesia by High Resolution fMRI and Diffusion Tensor Imaging/ Axonal Tracking in the Human Brainstem.
Neuroscience 354:178-195, 2017
Post-doc Fellow
University of Oxford Division of Clinical Neurology, United Kingdom

Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto da Universidade de São Paulo, Brazil
Conselho Nacional de Desenvolvimento Científico e Tecnológico
Concluded
1991/04/02 - 1991/10/14 Identificação de Neurônios Opióides e Serotoninérgicos do Teto Mesencefálico e seu Papel na Analgesia Induzida por Estimulação Intra-encefálica Aversiva
Brain Res. (1996), 736: 348-352
Behav. Brain Res. (1997), 87: 97-103
Exp. Neurol. (2006), 197: 93-112
PhD Student Fellow
Universidade de São Paulo Faculdade de Medicina de Ribeirão Preto, Brazil

Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto da Universidade de São Paulo, Brazil
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
Concluded
1989/03/01 - 1991/04/26 Influência de Vias GABAérgicas Nigro-coliculares sobre o Comportamento Aversivo Induzido pela Estimulação Elétrica e Química do Teto Mesencefálico de Rattus norvegicus (Rodentia, Muridae)
Behav. Brain Res. (1992), 50: 77-83
Behav. Brain Res. (1993), 59: 131-139
Master Student Fellow
Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto da Universidade de São Paulo, Brazil
 Conselho Nacional de Desenvolvimento Científico e Tecnológico
Concluded
1988/09/01 - 1989/02/28 Estudo Neuropsicofarmacológico das Projeções Estriado-nigro-tectais GABAérgicas
Braz. J. Med. Biol. Res. (1989), 22: 111-114
Neurosci. Biobehav. Rev. (1990), 14: 495-499
Research Fellow
Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto da Universidade de São Paulo, Brazil
 Conselho Nacional de Desenvolvimento Científico e Tecnológico
Concluded
1987/03/01 - 1988/08/31 Estudo do Efeito de Lesões Eletrolíticas e Neuroquímicas da Susbstância Negra, parte Reticulada, sobre as Respostas Neurovegetativas e Defensivas Evocadas por Estimulação Elétrica e Química do Teto Mesencefálico
Braz. J. Med. Biol. Res. (1988), 21: 1027-1031.
Scientific Initiation Fellow
Universidade Federal do Espírito Santo, Brazil
 Conselho Nacional de Desenvolvimento Científico e Tecnológico
Concluded
Outputs

Publications

Journal article
  1. Crespo, Luiz Gustavo Soares Carvalho; Leite Júnior, Joaquim Barbosa; de Mello Bastos, João Marcos; Samuels, Richard Ian; Coimbra, Norberto Cysne; Carey, Robert J.; Carrera, Marinete Pinheiro. "Context evoked morphine conditioned effects can be equivalent to morphine induced drug effects in terms of behavioral response and ERK activation in reward associated subcortical brain structures". Pharmacology Biochemistry and Behavior 214 (2022): 173356. http://dx.doi.org/10.1016/j.pbb.2022.173356.
    In press • 10.1016/j.pbb.2022.173356
  2. de Mello Rosa, Gustavo Henrique; Ullah, Farhad; de Paiva, Yara Bezerra; da Silva, Juliana Almeida; Branco, Luiz Guilherme S.; Corrado, Alexandre Pinto; Medeiros, Priscila; Coimbra, Norberto Cysne; Franceschi Biagioni, Audrey. "Ventrolateral periaqueductal gray matter integrative system of defense and antinociception". Pflügers Archiv - European Journal of Physiology (2022): http://dx.doi.org/10.1007/s00424-022-02672-0.
    Open access • In press • 10.1007/s00424-022-02672-0
  3. Beleboni, R. O.; Mortari, M. R.; Melo-Thomas, L.; Coimbra, N. C.. "Editorial: Classical and Modern Biotechnology Applied to the Treatment of Epilepsy and Anxiety Disorders". Frontiers in Pharmacology 12 824986 (2022): http://dx.doi.org/10.3389/fphar.2021.824986.
    Open access • Published • 10.3389/fphar.2021.824986 • Editor
  4. dos Anjos-Garcia, Tayllon; Kanashiro, Alexandre; de Campos, Alline Cristina; Coimbra, Norberto Cysne. "Environmental Enrichment Facilitates Anxiety in Conflict-Based Tests but Inhibits Predator Threat-Induced Defensive Behaviour in Male Mice". Neuropsychobiology (2022): 1-12. http://dx.doi.org/10.1159/000521184.
    In press • 10.1159/000521184
  5. de Almeida Silva, Marília; de Toledo, Thaís Seghese; de Figueiredo, Rebeca Machado; Leite-Panissi, Christie Ramos Andrade; Huston, Joseph P.; Coimbra, Norberto Cysne; Mattern, Claudia; de Carvalho, Milene Cristina. "The activation of D2-like receptors by intranasal dopamine facilitates the extinction of contextual fear and prevents conditioned fear-induced antinociception". Behavioural Brain Research 417 (2022): 113611. http://dx.doi.org/10.1016/j.bbr.2021.113611.
    Published • 10.1016/j.bbr.2021.113611
  6. B.B. de Paula; E.B. Vieira-Rasteli; F. Calvo; N.C. Coimbra; C.R.A. Leite-Panissi. "Functional activation of the periaqueductal gray matter during conditioned and unconditioned fear in guinea pigs confronted with the Boa constrictor constrictor snake". Brazilian Journal of Medical and Biological Research (2022): https://doi.org/10.1590/1414-431x2021e11542.
    10.1590/1414-431x2021e11542
  7. Bianca Feitosa Maia Fernandes; Diogo Rios de Avila; Vanessa Cristina Santana; Talles Henrique Pichinelli Maffei; Rafaela Vieira Streg; Júlia Serpa Vale; Rodolfo Cassimiro de Araújo Berber; et al. Corresponding author: Ricardo de Oliveira. "The blockade of µ-opioid receptors in lateral hypothalamus enhances panic attack-like behaviour and diminishes defensive antinociception". Acta Neurobiologiae Experimentalis (2022):
    Open access • In press
  8. Medeiros, Priscila; Medeiros, Ana Carolina; Coimbra, Jade Pissamiglio Cysne; Teixeira, Lucas Emmanuel ; Salgado-Rohner, Carlos Jose; da Silva, José Aparecido; Coimbra, Norberto Cysne; de Freitas, Renato Leonardo. Corresponding author: de Freitas, Renato Leonardo. "Physical, emotional and social pain during the COVID-19 pandemic-related social isolation". Trends in Psychology (2022):
    In press
  9. Ferreira-Sgobbi, Renata; Figueiredo, Rebeca Machado; Frias, Alana Tercino; Matthiesen, Melina; Batistela, Matheus Fitipaldi; Falconi-Sobrinho, Luiz Luciano; Vilela-Costa, Heloísa Helena; et al. "Panic-like responses of female Wistar rats confronted by Bothrops alternatus pit vipers, or exposure to acute hypoxia: Effect of oestrous cycle". European Journal of Neuroscience 55 1 (2021): 32-48. http://dx.doi.org/10.1111/ejn.15548.
    Published • 10.1111/ejn.15548
  10. Sylmara Esther Negrini-Ferrari; Priscila Medeiros; Rafael Braghetto Malvestio; Mariana de Oliveira Silva; Ana Carolina Medeiros; Norberto Cysne Coimbra; Helio Rubens Machado; Renato Leonardo de Freitas. "The primary motor cortex electrical and chemical stimulation attenuates the chronic neuropathic pain by activation of the periaqueductal grey matter: The role of NMDA receptors". Behavioural Brain Research 415 (2021): 113522-113522. https://doi.org/10.1016/j.bbr.2021.113522.
    10.1016/j.bbr.2021.113522
  11. Dias, Fabiolla Patusco; Carvalho Crespo, Luiz Gustavo Soares; Leite Junior, Joaquim Barbosa; Samuels, Richard Ian; Coimbra, Norberto Cysne; Carey, Robert J.; Carrera, Marinete Pinheiro. "Morphine reward effects and morphine behavioral sensitization: The adventitious association of morphine activation of brain reward effects with ongoing spontaneous activity". Pharmacology Biochemistry and Behavior 209 (2021): 173244. http://dx.doi.org/10.1016/j.pbb.2021.173244.
    Published • 10.1016/j.pbb.2021.173244
  12. Linares, Ila M.P.; Nardi, Antonio E.; Guimarães, Francisco S.; Arrais, Katia C.; Chagas, Marcos H.; Osório, Flavia L.; Hallak, Jaime E.; et al. "Increased body sway in phobic patients exposed to images of spiders". Brazilian Journal of Psychiatry 43 5 (2021): 477-483. http://dx.doi.org/10.1590/1516-4446-2020-1466.
    Open access • Published • 10.1590/1516-4446-2020-1466
  13. R.B. Malvestio; P. Medeiros; S.E. Negrini-Ferrari; M. Oliveira-Silva; A.C. Medeiros; C.M. Padovan; L. Luongo; et al. "Cannabidiol in the prelimbic cortex modulates the comorbid condition between the chronic neuropathic pain and depression-like behaviour in rats: The role of medial prefrontal cortex 5-HT1A and CB1 receptors". Brain Research Bulletin 174 (2021): 323-338. https://doi.org/10.1016/j.brainresbull.2021.06.017.
    Published • 10.1016/j.brainresbull.2021.06.017
  14. Medeiros, Ana C.; Medeiros, Priscila; Freitas, Renato L.; Silva Júnior, Pedro Ismael; Coimbra, Norberto C.; Santos, Wagner F.. "Acanthoscurria gomesiana spider-derived synthetic mygalin in the dorsal raphe nucleus modulates acute and chronic pain". Journal of Biochemical and Molecular Toxicology 35 10 (2021): e22877. http://dx.doi.org/10.1002/jbt.22877.
    Published • 10.1002/jbt.22877
  15. Soares, Victor P.M.N.; de Andrade, Telma G.C.S.; Canteras, Newton S.; Coimbra, Norberto C.; Wotjak, Carsten T.; Almada, Rafael C.. "Orexin 1 and 2 Receptors in the Prelimbic Cortex Modulate Threat Valuation". Neuroscience 468 (2021): 158-167. http://dx.doi.org/10.1016/j.neuroscience.2021.06.006.
    Published • 10.1016/j.neuroscience.2021.06.006
  16. de Fátima dos Santos Sampaio, Maria; Santana Bastos Boechat, Marcela; Augusto Gusman Cunha, Igor; Gonzaga Pereira, Messias; Cysne Coimbra, Norberto; Giraldi-Guimarães, Arthur. "Neurotrophin-3 upregulation associated with intravenous transplantation of bone marrow mononuclear cells induces axonal sprouting and motor functional recovery in the long term after neocortical ischaemia". Brain Research 1758 (2021): 147292. http://dx.doi.org/10.1016/j.brainres.2021.147292.
    Published • 10.1016/j.brainres.2021.147292
  17. Franceschi Biagioni, Audrey; Cellot, Giada; Pati, Elisa; Lozano, Neus; Ballesteros, Belén; Casani, Raffaele; Coimbra, Norberto Cysne; Kostarelos, Kostas; Ballerini, Laura. "Graphene oxide prevents lateral amygdala dysfunctional synaptic plasticity and reverts long lasting anxiety behavior in rats". Biomaterials 271 (2021): 120749. http://dx.doi.org/10.1016/j.biomaterials.2021.120749.
    Open access • Published • 10.1016/j.biomaterials.2021.120749
  18. Almada, Rafael Carvalho; dos Anjos-Garcia, Tayllon; da Silva, Juliana Almeida; Pigatto, Glauce Regina; Wotjak, Carsten T.; Coimbra, Norberto Cysne. "The modulation of striatonigral and nigrotectal pathways by CB1 signalling in the substantia nigra pars reticulata regulates panic elicited in mice by urutu-cruzeiro lancehead pit vipers". Behavioural Brain Research 401 (2021): 112996. http://dx.doi.org/10.1016/j.bbr.2020.112996.
    Published • 10.1016/j.bbr.2020.112996
  19. Luiz Luciano Falconi-Sobrinho; Tayllon dos Anjos-Garcia; Norberto Cysne Coimbra. "Nitric oxide-mediated defensive and antinociceptive responses organised at the anterior hypothalamus of mice are modulated by glutamatergic inputs from area 24b of the cingulate cortex". Journal of Psychopharmacology 35 1 (2021): 78-90. https://doi.org/10.1177/0269881120967881.
    Published • 10.1177/0269881120967881
  20. Medeiros, Priscila; Oliveira-Silva, Mariana; Negrini-Ferrari, Sylmara Esther; Medeiros, Ana Carolina; Elias-Filho, Daoud Hibraim; Coimbra, Norberto Cysne; de Freitas, Renato Leonardo. "CB1-cannabinoid-, TRPV1-vanilloid- and NMDA-glutamatergic-receptor-signalling systems interact in the prelimbic cerebral cortex to control neuropathic pain symptoms". Brain Research Bulletin 165 (2020): 118-128. http://dx.doi.org/10.1016/j.brainresbull.2020.09.013.
    Published • 10.1016/j.brainresbull.2020.09.013
  21. De Medeiros, Priscila; Medeiros, Ana Carolina; Pereira Martins, Renata; Negrini-Ferrari, Sylmara Esther; Almeida Da Silva, Juliana; Da Silva, José Aparecido; Cysne Coimbra, Norberto; Leonardo de Freitas, Renato. "Modelos neuropsicobiológicos para estudo da dor e das emoções". Revista Psicologia em Pesquisa 14 3 (2020): 66-82. http://dx.doi.org/10.34019/1982-1247.2020.v14.30596.
    Published • 10.34019/1982-1247.2020.v14.30596
  22. Mendes-Gomes, Joyce; Paschoalin-Maurin, Tatiana; Donaldson, Lucy F.; Lumb, Bridget M.; Caroline Blanchard, D.; Cysne Coimbra, Norberto. "Repeated exposure of naïve and peripheral nerve-injured mice to a snake as an experimental model of post-traumatic stress disorder and its co-morbidity with neuropathic pain". Brain Research 1744 (2020): 146907. http://dx.doi.org/10.1016/j.brainres.2020.146907.
    Published • 10.1016/j.brainres.2020.146907
  23. Medeiros, Priscila; dos Santos, Ieda Regina; Júnior, Ivair Matias; Palazzo, Enza; da Silva, José Aparecido; Machado, Hélio Rubens; Ferreira, Sérgio Henrique; et al. "An Adapted Chronic Constriction Injury of the Sciatic Nerve Produces Sensory, Affective, and Cognitive Impairments: A Peripheral Mononeuropathy Model for the Study of Comorbid Neuropsychiatric Disorders Associated with Neuropathic Pain in Rats". Pain Medicine 22 2 (2020): 338-351. http://dx.doi.org/10.1093/pm/pnaa206.
    Published • 10.1093/pm/pnaa206
  24. Juliana Almeida da Silva; Rafael Carvalho Almada; Yara Bezerra de Paiva; Norberto Cysne Coimbra. "Endocannabinoid neuromodulation in the neostriatum decreases the GABAergic striato-nigral disinhibitory function and increases the nigro-collicular inhibitory pathway activity". Journal of Neural Transmission 127 8 (2020): 1199-1208. https://doi.org/10.1007/s00702-020-02217-8.
    10.1007/s00702-020-02217-8
  25. dos Santos Sampaio, Maria de Fátima; Giraldi-Guimarães, Arthur; da Silva Lourenço, Camila; Pereira, Messias Gonzaga; Coimbra, Norberto Cysne. "Effects of bone marrow mononuclear cells on induction of axonal sprouting in cortico-cortical and cortico-striatal pathways in an animal model of cortical ablation". BMC Research Notes 13 1 (2020): 272. http://dx.doi.org/10.1186/s13104-020-05116-z.
    Open access • Published • 10.1186/s13104-020-05116-z
  26. Pigatto, Glauce R.; Quinteiro, Maiara H.S.; Nunes-de-Souza, Ricardo L.; Coimbra, Norberto C.; Parizotto, Nivaldo A.; Glauce R. Pigatto; Maiara H.S. Quinteiro; et al. "Low-Intensity Photobiomodulation Decreases Neuropathic Pain in Paw Ischemia-Reperfusion and Spared Nervus Ischiadicus Injury Experimental Models". Pain Practice 20 4 (2020): 371-386. http://dx.doi.org/10.1111/papr.12862.
    Published • 10.1111/papr.12862
  27. Mendes-Gomes, Joyce; Motta, Simone Cristina; Passoni Bindi, Ricardo; de Oliveira, Amanda Ribeiro; Ullah, Farhad; Baldo, Marcus Vinicius C.; Coimbra, Norberto Cysne; Canteras, Newton Sabino; Blanchard, D. Caroline. "Defensive behaviors and brain regional activation changes in rats confronting a snake". Behavioural Brain Research 381 (2020): 112469. http://dx.doi.org/10.1016/j.bbr.2020.112469.
    Published • 10.1016/j.bbr.2020.112469
  28. Bassi, Gabriel S.; Kanashiro, Alexandre; Coimbra, Norberto C.; Terrando, Niccolò; Maixner, William; Ulloa, Luis. "Anatomical and clinical implications of vagal modulation of the spleen". Neuroscience & Biobehavioral Reviews 112 (2020): 363-373. http://dx.doi.org/10.1016/j.neubiorev.2020.02.011.
    Published • 10.1016/j.neubiorev.2020.02.011
  29. Medeiros, Priscila; Freitas, Renato Leonardo; Boccella, Serena; Iannotta, Monica; Belardo, Carmela; Mazzitelli, Mariacristina; Romano, Rosaria; et al. "Characterization of the sensory, affective, cognitive, biochemical, and neuronal alterations in a modified chronic constriction injury model of neuropathic pain in mice". Journal of Neuroscience Research 98 2 (2020): 338-352. http://dx.doi.org/10.1002/jnr.24501.
    Published • 10.1002/jnr.24501
  30. Asmat Ullah Khan; Luiz Luciano Falconi-Sobrinho; Tayllon dos Anjos-Garcia; Maria de Fátima dos Santos Sampaio; José Alexandre de Souza Crippa; Leda Menescal-de-Oliveira; Norberto Cysne Coimbra. "Cannabidiol-induced panicolytic-like effects and fear-induced antinociception impairment: the role of the CB1 receptor in the ventromedial hypothalamus". Psychopharmacology 337 4 (2020): 1063-1079. https://doi.org/10.1007/s00213-019-05435-5.
    Published • 10.1007/s00213-019-05435-5
  31. dos Anjos-Garcia, Tayllon; Coimbra, Norberto Cysne. "Anandamide in the anterior hypothalamus diminishes defensive responses elicited in mice threatened by Epicrates cenchria constrictor serpents". Acta Neurobiologiae Experimentalis 80 2 (2020): 179-191. http://dx.doi.org/10.21307/ane-2020-017.
    Open access • Published • 10.21307/ane-2020-017
  32. P. Medeiros; I.R. dos Santos; A.C. Medeiros; J.A. da Silva; S.H. Ferreira; R.L. de Freitas; N.C. Coimbra. "Indomethacin attenuates mechanical allodynia during the organization but not the maintenance of the peripheral neuropathic pain induced by nervus ischiadicus chronic constriction injury". Brazilian Journal of Medical and Biological Research 53 5 (2020): e9255. https://doi.org/10.1590/1414-431x20209255.
    Open access • Published • 10.1590/1414-431x20209255
  33. Abad, Alberto; da Silva, Juliana Almeida; das Neves Braga, J.V.Z.; Medeiros, Priscila; de Freitas, Renato Leonardo; Coimbra, Norberto Cysne; da Silva, José Aparecido. "Preparing for the COVID-19 Mental Health Crisis in Latin America—Using Early Evidence from Countries that Experienced COVID-19 First". Advances in Infectious Diseases 10 03 (2020): 40-44. http://dx.doi.org/10.4236/aid.2020.103005.
    Open access • Published • 10.4236/aid.2020.103005
  34. Uribe-Mariño, Andrés; Castiblanco-Urbina, Maria Angélica; Falconi-Sobrinho, Luiz Luciano; dos Anjos-Garcia, Tayllon; de Oliveira, Rithiele Cristina; Mendes-Gomes, Joyce; da Silva Soares Jr., Raimundo; et al. "The alpha- and beta-noradrenergic receptors blockade in the dorsal raphe nucleus impairs the panic-like response elaborated by medial hypothalamus neurons". Brain Research 1725 (2019): 146468. http://dx.doi.org/10.1016/j.brainres.2019.146468.
    Published • 10.1016/j.brainres.2019.146468
  35. de Carvalho, Milene Cristina; Figueiredo, Rebeca Machado de; Coimbra, Norberto Cysne; Leite-Panissi, Christie Ramos Andrade; de Souza Silva, Maria Angélica; Huston, Joseph P; Mattern, Claudia; Brandão, Marcus Lira. "Intranasal dopamine attenuates fear responses induced by electric shock to the foot and by electrical stimulation of the dorsal periaqueductal gray matter". Journal of Psychopharmacology 33 12 (2019): 1524-1532. http://dx.doi.org/10.1177/0269881119862527.
    Published • 10.1177/0269881119862527
  36. da Silva Soares, Raimundo; Falconi-Sobrinho, Luiz Luciano; Almada, Rafael Carvalho; Coimbra, Norberto Cysne. "Dorsal raphe nucleus 5-Hydroxytryptamine 2A receptors are critical for the organisation of panic attack-like defensive behaviour and unconditioned fear-induced antinociception elicited by the chemical stimulation of superior colliculus neurons". European Neuropsychopharmacology 29 7 (2019): 858-870. http://dx.doi.org/10.1016/j.euroneuro.2019.05.007.
    Published • 10.1016/j.euroneuro.2019.05.007
  37. Medeiros, Priscila; Negrini-Ferrari, Sylmara Esther; Palazzo, Enza; Maione, Sabatino; Ferreira, Sérgio Henrique; de Freitas, Renato Leonardo; Coimbra, Norberto Cysne. "N-methyl-d-aspartate Receptors in the Prelimbic Cortex are Critical for the Maintenance of Neuropathic Pain". Neurochemical Research 44 9 (2019): 2068-2080. http://dx.doi.org/10.1007/s11064-019-02843-z.
    Published • 10.1007/s11064-019-02843-z
  38. Brandão, Marcus L.; Coimbra, Norberto C.. "Understanding the role of dopamine in conditioned and unconditioned fear". Reviews in the Neurosciences 30 3 (2019): 325-337. http://dx.doi.org/10.1515/revneuro-2018-0023.
    Published • 10.1515/revneuro-2018-0023
  39. Matias, Ivair; Elias-Filho, Daoud Hibrahim; Garcia, Camila Araújo Bernardino; Silva, Guilherme Henrique; Mejia, Jorge; Cabral, Francisco Romero; Miranda, Ana Cláudia Camargo; et al. "A new model of experimental hemispherotomy in young adult Rattus norvegicus: a neural tract tracing and SPECT in vivo study". Journal of Neurosurgery 130 4 (2019): 1210-1223. http://dx.doi.org/10.3171/2017.12.jns171150.
    Open access • Published • 10.3171/2017.12.jns171150
  40. Calvo, Fabrício; Almada, Rafael Carvalho; dos Anjos-Garcia, Tayllon; Falconi- Sobrinho, Luiz Luciano; Paschoalin-Maurin, Tatiana; Bazaglia-de-Sousa, Guilherme; Medeiros, Priscila; et al. "Panicolytic-like effect of µ1-opioid receptor blockade in the inferior colliculus of prey threatened by Crotalus durissus terrificus pit vipers". Journal of Psychopharmacology 33 5 (2019): 577-588. http://dx.doi.org/10.1177/0269881118822078.
    Published • 10.1177/0269881118822078
  41. da Silva Soares, Raimundo; Falconi-Sobrinho, Luiz Luciano; dos Anjos-Garcia, Tayllon; Coimbra, Norberto Cysne. "5-Hydroxytryptamine 2A receptors of the dorsal raphe nucleus modulate panic-like behaviours and mediate fear-induced antinociception elicited by neuronal activation in the central nucleus of the inferior colliculus". Behavioural Brain Research 357-358 (2019): 71-81. http://dx.doi.org/10.1016/j.bbr.2017.07.016.
    Published • 10.1016/j.bbr.2017.07.016
  42. dos Anjos-Garcia, Tayllon; Coimbra, Norberto Cysne. "Opposing roles of dorsomedial hypothalamic CB1 and TRPV1 receptors in anandamide signaling during the panic-like response elicited in mice by Brazilian rainbow Boidae snakes". Psychopharmacology 236 6 (2019): 1863-1874. http://dx.doi.org/10.1007/s00213-019-5170-2.
    Published • 10.1007/s00213-019-5170-2
  43. Calvo, Fabrício; Almada, Rafael Carvalho; da Silva, Juliana Almeida; Medeiros, Priscila; da Silva Soares Jr., Raimundo; de Paiva, Yara Bezerra; Roncon, Camila Marroni; Coimbra, Norberto Cysne. "The Blockade of µ1- and k-Opioid Receptors in the Inferior Colliculus Decreases the Expression of Panic Attack-Like Behaviours Induced by Chemical Stimulation of the Dorsal Midbrain". Neuropsychobiology 78 4 (2019): 218-228. http://dx.doi.org/10.1159/000502439.
    Published • 10.1159/000502439
  44. Calvo, Fabrício; Lobão-Soares, Bruno; de Freitas, Renato Leonardo; Paschoalin-Maurin, Tatiana; dos Anjos-Garcia, Tayllon; Medeiros, Priscila; da Silva, Juliana Almeida; Lovick, Thelma Anderson; Coimbra, Norberto Cysne. "The endogenous opioid system modulates defensive behavior evoked by Crotalus durissus terrificus: Panicolytic-like effect of intracollicular non-selective opioid receptors blockade". Journal of Psychopharmacology 33 1 (2018): 51-61. http://dx.doi.org/10.1177/0269881118806301.
    Published • 10.1177/0269881118806301
  45. de Oliveira, Rithiele Cristina; de Oliveira, Ricardo; Falconi-Sobrinho, Luiz Luciano; Biagioni, Audrey Franceschi; Almada, Rafael Carvalho; dos Anjos-Garcia, Tayllon; Bazaglia-de-Sousa, Guilherme; Khan, Asmat Ullah; Coimbra, Norberto Cysne. "Neurotoxic lesions of the pedunculopontine tegmental nucleus impair the elaboration of postictal antinociception". Physiology & Behavior 194 (2018): 162-169. http://dx.doi.org/10.1016/j.physbeh.2018.05.011.
    Published • 10.1016/j.physbeh.2018.05.011
  46. Vieira-Rasteli, Eveline Bis; de Paula, Bruna Balbino; de Paiva, Yara Bezerra; Coimbra, Norberto Cysne; Leite-Panissi, Christie Ramos Andrade. "Restricted lesions of the ventrolateral or dorsal columns of the periaqueductal gray promotes distinct effects on tonic immobility and defensive analgesia in guinea pigs". Physiology & Behavior 194 (2018): 538-544. http://dx.doi.org/10.1016/j.physbeh.2018.07.003.
    Published • 10.1016/j.physbeh.2018.07.003
  47. da Silva, Juliana Almeida; Almada, Rafael Carvalho; de Figueiredo, Rebeca Machado; Coimbra, Norberto Cysne. "Blockade of synaptic activity in the neostriatum and activation of striatal efferent pathways produce opposite effects on panic attack-like defensive behaviours evoked by GABAergic disinhibition in the deep layers of the superior colliculus". Physiology & Behavior 196 (2018): 104-111. http://dx.doi.org/10.1016/j.physbeh.2018.07.021.
    Published • 10.1016/j.physbeh.2018.07.021
  48. Bassi, G.S.; Kanashiro, A.; Rodrigues, G.J.; Cunha, F.Q.; Coimbra, N.C.; Ulloa, L.. "Brain Stimulation Differentially Modulates Nociception and Inflammation in Aversive and Non-aversive Behavioral Conditions". Neuroscience 383 (2018): 191-204. http://dx.doi.org/10.1016/j.neuroscience.2018.05.008.
    Open access • Published • 10.1016/j.neuroscience.2018.05.008
  49. Falconi-Sobrinho, Luiz Luciano; Coimbra, Norberto Cysne. "The Nitric Oxide Donor SIN-1-Produced Panic-Like Behaviour And Fear-Induced Antinociception Are Modulated By NMDA Receptors In The Anterior Hypothalamus". Journal of Psychopharmacology 32 6 (2018): 711-722. http://dx.doi.org/10.1177/0269881118769061.
    Published • 10.1177/0269881118769061
  50. Almada, Rafael C.; Genewsky, Andreas J.; Heinz, Daniel E.; Kaplick, Paul M.; Coimbra, Norberto C.; Wotjak, Carsten T.. "Stimulation of the Nigrotectal Pathway at the Level of the Superior Colliculus Reduces Threat Recognition and Causes a Shift From Avoidance to Approach Behavior". Frontiers in Neural Circuits 12 36 (2018): 36. http://dx.doi.org/10.3389/fncir.2018.00036.
    Open access • Published • 10.3389/fncir.2018.00036
  51. Paschoalin-Maurin, Tatiana; dos Anjos-Garcia, Tayllon; Falconi-Sobrinho, Luiz Luciano; de Freitas, Renato Leonardo; Coimbra, Jade Pissamiglio Cysne; Laure, Carlos Júlio; Coimbra, Norberto Cysne. "The Rodent-versus-wild Snake Paradigm as a Model for Studying Anxiety- and Panic-like Behaviors: Face, Construct and Predictive Validities". Neuroscience 369 (2018): 336-349. http://dx.doi.org/10.1016/j.neuroscience.2017.11.031.
    Published • 10.1016/j.neuroscience.2017.11.031
  52. Falconi-Sobrinho, Luiz Luciano; dos Anjos-Garcia, Tayllon; de Oliveira, Ricardo; Coimbra, Norberto Cysne. "Decrease in NMDA receptor-signalling activity in the anterior cingulate cortex diminishes defensive behaviour and unconditioned fear-induced antinociception elicited by GABAergic tonic inhibition impairment in the posterior hypothalamus". European Neuropsychopharmacology 27 11 (2017): 1120-1131. http://dx.doi.org/10.1016/j.euroneuro.2017.09.002.
    Published • 10.1016/j.euroneuro.2017.09.002
  53. da Silva, Juliana Almeida; Biagioni, Audrey Franceschi; Almada, Rafael Carvalho; de Freitas, Renato Leonardo; Coimbra, Norberto Cysne. "Panicolytic-like effects caused by substantia nigra pars reticulata pretreatment with low doses of endomorphin-1 and high doses of CTOP or the NOP receptors antagonist JTC-801 in male Rattus norvegicus". Psychopharmacology 234 20 (2017): 3009-3025. http://dx.doi.org/10.1007/s00213-017-4678-6.
    Published • 10.1007/s00213-017-4678-6
  54. Coimbra, Norberto Cysne; Calvo, Fabrício; Almada, Rafael Carvalho; Freitas, Renato Leonardo; Paschoalin-Maurin, Tatiana; dos Anjos-Garcia, Tayllon; Elias-Filho, Daoud Hibrahim; et al. "Opioid neurotransmission modulates defensive behavior and fear-induced antinociception in dangerous environments". Neuroscience 354 (2017): 178-195. http://dx.doi.org/10.1016/j.neuroscience.2017.04.032.
    Published • 10.1016/j.neuroscience.2017.04.032
  55. Ullah, Farhad; dos Anjos-Garcia, Tayllon; Mendes-Gomes, Joyce; Elias-Filho, Daoud Hibrahim; Falconi-Sobrinho, Luiz Luciano; Freitas, Renato Leonardo de; Khan, Asmat Ullah; Oliveira, Ricardo de; Coimbra, Norberto Cysne. "Connexions between the dorsomedial division of the ventromedial hypothalamus and the dorsal periaqueductal grey matter are critical in the elaboration of hypothalamically mediated panic-like behaviour". Behavioural Brain Research 319 (2017): 135-147. http://dx.doi.org/10.1016/j.bbr.2016.11.026.
    Published • 10.1016/j.bbr.2016.11.026
  56. Coimbra, Norberto C.; Paschoalin-Maurin, Tatiana; Bassi, Gabriel S.; Kanashiro, Alexandre; Biagioni, Audrey F.; Felippotti, Tatiana T.; Elias-Filho, Daoud H.; et al. "Critical neuropsychobiological analysis of panic attack- and anticipatory anxiety-like behaviors in rodents confronted with snakes in polygonal arenas and complex labyrinths: a comparison to the elevated plus- and T-maze behavioral tests". Revista Brasileira de Psiquiatria 39 1 (2017): 72-83. http://dx.doi.org/10.1590/1516-4446-2015-1895.
    Open access • Published • 10.1590/1516-4446-2015-1895
  57. Falconi-Sobrinho, Luiz Luciano; dos Anjos-Garcia, Tayllon; Elias-Filho, Daoud Hibrahim; Coimbra, Norberto Cysne. "Unravelling cortico-hypothalamic pathways regulating unconditioned fear-induced antinociception and defensive behaviours". Neuropharmacology 113 (2017): 367-385. http://dx.doi.org/10.1016/j.neuropharm.2016.10.001.
    Published • 10.1016/j.neuropharm.2016.10.001
  58. Roncon, Camila Marroni; Yamashita, Paula Shimene de Melo; Frias, Alana Tercino; Audi, Elisabeth Aparecida; Graeff, Frederico Guilherme; Coimbra, Norberto Cysne; Zangrossi, Helio. "µ-Opioid and 5-HT1A receptors in the dorsomedial hypothalamus interact for the regulation of panic-related defensive responses". Journal of Psychopharmacology 31 6 (2017): 715-721. http://dx.doi.org/10.1177/0269881117693747.
    Published • 10.1177/0269881117693747
  59. Tayllon dos Anjos-Garcia; Farhad Ullah; Luiz Luciano Falconi-Sobrinho; Norberto Cysne Coimbra. "CB1 cannabinoid receptor-mediated anandamide signalling reduces the defensive behaviour evoked through GABAA receptor blockade in the dorsomedial division of the ventromedial hypothalamus". Neuropharmacology 113 PtA (2017): 156-166. https://doi.org/10.1016/j.neuropharm.2016.04.003.
    Published • 10.1016/j.neuropharm.2016.04.003
  60. de Oliveira, Ricardo; de Oliveira, Rithiele Cristina; Falconi-Sobrinho, Luiz Luciano; da Silva Soares, Raimundo; Coimbra, Norberto Cysne. "5-Hydroxytryptamine 2A/2C receptors of nucleus raphe magnus and gigantocellularis/paragigantocellularis pars a reticular nuclei modulate the unconditioned fear-induced antinociception evoked by electrical stimulation of deep layers of the superior colliculus and dorsal periaqueductal grey matter". Behavioural Brain Research 316 (2017): 294-304. http://dx.doi.org/10.1016/j.bbr.2016.09.016.
    Published • 10.1016/j.bbr.2016.09.016
  61. Medeiros, P.; de Freitas, R.L.; Silva, M.O.; Coimbra, N.C.; Melo-Thomas, L.. "CB1 cannabinoid receptor-mediated anandamide signaling mechanisms of the inferior colliculus modulate the haloperidol-induced catalepsy". Neuroscience 337 (2016): 17-26. http://dx.doi.org/10.1016/j.neuroscience.2016.08.047.
    Published • 10.1016/j.neuroscience.2016.08.047
  62. de Freitas, Renato Leonardo; Medeiros, Priscila; da Silva, Juliana Almeida; de Oliveira, Rithiele Cristina; de Oliveira, Ricardo; Ullah, Farhad; Khan, Asmat Ullah; Coimbra, Norberto Cysne. "The µ1-opioid receptor and 5-HT2A- and 5HT2C-serotonergic receptors of the locus coeruleus are critical in elaborating hypoalgesia induced by tonic and tonic–clonic seizures". Neuroscience 336 (2016): 133-145. http://dx.doi.org/10.1016/j.neuroscience.2016.08.040.
    Published • 10.1016/j.neuroscience.2016.08.040
  63. de Oliveira, Rithiele Cristina; de Oliveira, Ricardo; Biagioni, Audrey Franceschi; Falconi-Sobrinho, Luiz Luciano; dos Anjos-Garcia, Tayllon; Coimbra, Norberto Cysne. "Nicotinic and muscarinic cholinergic receptors are recruited by acetylcholine-mediated neurotransmission within the locus coeruleus during the organisation of post-ictal antinociception". Brain Research Bulletin 127 (2016): 74-83. http://dx.doi.org/10.1016/j.brainresbull.2016.08.011.
    Published • 10.1016/j.brainresbull.2016.08.011
  64. de Freitas, Renato Leonardo; Medeiros, Priscila; Khan, Asmat Ullah; Coimbra, Norberto Cysne. "µ1-Opioid receptors in the dorsomedial and ventrolateral columns of the periaqueductal grey matter are critical for the enhancement of post-ictal antinociception". Synapse 70 12 (2016): 519-530. http://dx.doi.org/10.1002/syn.21926.
    Published • 10.1002/syn.21926
  65. Biagioni, Audrey Franceschi; de Oliveira, Rithiele Cristina; de Oliveira, Ricardo; da Silva, Juliana Almeida; Anjos-Garcia, Tayllon dos; Roncon, Camila Marroni; Corrado, Alexandre Pinto; Zangrossi, Hélio; Coimbra, Norberto Cysne. "5-Hydroxytryptamine 1A receptors in the dorsomedial hypothalamus connected to dorsal raphe nucleus inputs modulate defensive behaviours and mediate innate fear-induced antinociception". European Neuropsychopharmacology 26 3 (2016): 532-545. http://dx.doi.org/10.1016/j.euroneuro.2015.12.032.
    Published • 10.1016/j.euroneuro.2015.12.032
  66. Biagioni, Audrey Francisco; Anjos-Garcia, Tayllon dos; Ullah, Farhad; Fisher, Isaac René; Falconi-Sobrinho, Luiz Luciano; Freitas, Renato Leonardo de; Felippotti, Tatiana Tocchini; Coimbra, Norberto Cysne. "Neuroethological validation of an experimental apparatus to evaluate oriented and non-oriented escape behaviours: Comparison between the polygonal arena with a burrow and the circular enclosure of an open-field test". Behavioural Brain Research 298 (2016): 65-77. http://dx.doi.org/10.1016/j.bbr.2015.10.059.
    Published • 10.1016/j.bbr.2015.10.059
  67. de Oliveira, Rithiele Cristina; de Oliveira, Ricardo; Biagioni, Audrey Francisco; Falconi-Sobrinho, Luiz Luciano; Coimbra, Norberto Cysne. "Dorsal raphe nucleus acetylcholine-mediated neurotransmission modulates post-ictal antinociception: The role of muscarinic and nicotinic cholinergic receptors". Brain Research 1631 (2016): 80-91. http://dx.doi.org/10.1016/j.brainres.2015.11.014.
    Published • 10.1016/j.brainres.2015.11.014
  68. Roncon, Camila Marroni; Almada, Rafael Carvalho; Maraschin, Jhonatan Christian; Audi, Elisabeth Aparecida; Zangrossi, Hélio; Graeff, Frederico Guilherme; Coimbra, Norberto Cysne. "Pharmacological evidence for the mediation of the panicolytic effect of fluoxetine by dorsal periaqueductal gray matter µ-opioid receptors". Neuropharmacology 99 (2015): 620-626. http://dx.doi.org/10.1016/j.neuropharm.2015.08.037.
    Published • 10.1016/j.neuropharm.2015.08.037
  69. Ullah, Farhad; dos Anjos-Garcia, Tayllon; dos Santos, Ieda Regina; Biagioni, Audrey Francisco; Coimbra, Norberto Cysne. "Relevance of dorsomedial hypothalamus, dorsomedial division of the ventromedial hypothalamus and the dorsal periaqueductal gray matter in the organization of freezing or oriented and non-oriented escape emotional behaviors". Behavioural Brain Research 293 (2015): 143-152. http://dx.doi.org/10.1016/j.bbr.2015.07.013.
    Published • 10.1016/j.bbr.2015.07.013
  70. Almada, R.C.; Roncon, C.M.; Elias-Filho, D.H.; Coimbra, N.C.. "Endocannabinoid signaling mechanisms in the substantia nigra pars reticulata modulate GABAergic nigrotectal pathways in mice threatened by urutu-cruzeiro venomous pit viper". Neuroscience 303 (2015): 503-514. http://dx.doi.org/10.1016/j.neuroscience.2015.06.048.
    Published • 10.1016/j.neuroscience.2015.06.048
  71. da Silva, Juliana Almeida; Biagioni, Audrey Francisco; Almada, Rafael Carvalho; de Souza Crippa, José Alexandre; Cecílio Hallak, Jaime Eduardo; Zuardi, Antônio Waldo; Coimbra, Norberto Cysne. "Dissociation between the panicolytic effect of cannabidiol microinjected into the substantia nigra, pars reticulata, and fear-induced antinociception elicited by bicuculline administration in deep layers of the superior colliculus: The role of CB1-cannabinoid receptor in the ventral mesencephalon". European Journal of Pharmacology 758 (2015): 153-163. http://dx.doi.org/10.1016/j.ejphar.2015.03.051.
    Published • 10.1016/j.ejphar.2015.03.051
  72. Almada, Rafael Carvalho; Coimbra, Norberto Cysne. "Recruitment of striatonigral disinhibitory and nigrotectal inhibitory GABAergic pathways during the organization of defensive behavior by mice in a dangerous environment with the venomous snakeBothrops alternatus(Reptilia,Viperidae)". Synapse 69 6 (2015): 299-313. http://dx.doi.org/10.1002/syn.21814.
    Published • 10.1002/syn.21814
  73. Twardowschy, André; Cysne Coimbra, Norberto. "µ- and ¿-Opioid receptor activation in the dorsal periaqueductal grey matter differentially modulates panic-like behaviours induced by electrical and chemical stimulation of the inferior colliculus". Brain Research 1597 (2015): 168-179. http://dx.doi.org/10.1016/j.brainres.2014.11.062.
    Published • 10.1016/j.brainres.2014.11.062
  74. Almada, R.C.; Coimbra, N.C.; Brandão, M.L.. "Medial prefrontal cortex serotonergic and GABAergic mechanisms modulate the expression of contextual fear: Intratelencephalic pathways and differential involvement of cortical subregions". Neuroscience 284 (2015): 988-997. http://dx.doi.org/10.1016/j.neuroscience.2014.11.001.
    Published • 10.1016/j.neuroscience.2014.11.001
  75. Linares, I.M.P.; Jackowski, A.P.; Trzesniak, C.M.F.; Arrais, K.C.; Chagas, M.H.N.; Sato, J.R.; Santos, A.C.; et al. "Cortical thinning of the right anterior cingulate cortex in spider phobia: A magnetic resonance imaging and spectroscopy study". Brain Research 1576 (2014): 35-42. http://dx.doi.org/10.1016/j.brainres.2014.05.040.
    Published • 10.1016/j.brainres.2014.05.040
  76. Mazzei-Silva, Elaine Cristina; de Oliveira, Rithiele Cristina; Garcia, Tayllon Dos Anjos; Falconi-Sobrinho, Luiz Luciano; Almada, Rafael Carvalho; Coimbra, Norberto Cysne. "Intrinsic connections within the pedunculopontine tegmental nucleus are critical to the elaboration of post-ictal antinociception". Synapse 68 8 (2014): 369-377. http://dx.doi.org/10.1002/syn.21749.
    Published • 10.1002/syn.21749
  77. de Freitas, Renato Leonardo; de Oliveira, Rithiele Cristina; de Oliveira, Ricardo; Paschoalin-Maurin, Tatiana; de Aguiar Corrêa, Fernando Morgan; Coimbra, Norberto Cysne. "The role of dorsomedial and ventrolateral columns of the periaqueductal gray matter and in situ 5-HT2Aand 5-HT2Cserotonergic receptors in post-ictal antinociception". Synapse 68 1 (2013): 16-30. http://dx.doi.org/10.1002/syn.21697.
    Published • 10.1002/syn.21697
  78. de Freitas, Renato Leonardo; Salgado-Rohner, Carlos José; Hallak, Jaime Eduardo Cecílio; de Souza Crippa, José Alexandre; Coimbra, Norberto Cysne. "Involvement of prelimbic medial prefrontal cortex in panic-like elaborated defensive behaviour and innate fear-induced antinociception elicited by GABAA receptor blockade in the dorsomedial and ventromedial hypothalamic nuclei: role of the endocannabinoid CB1 receptor". International Journal of Neuropsychopharmacology 16 8 (2013): 1781-1798. http://dx.doi.org/10.1017/s1461145713000163.
    Open access • Published • 10.1017/s1461145713000163
  79. Twardowschy, André; Castiblanco-Urbina, Maria Angélica; Uribe-Mariño, Andres; Biagioni, Audrey Francisco; Salgado-Rohner, Carlos José; Crippa, José Alexandre de Souza; Coimbra, Norberto Cysne. "The role of 5-HT1A receptors in the anti-aversive effects of cannabidiol on panic attack-like behaviors evoked in the presence of the wild snake Epicrates cenchria crassus (Reptilia, Boidae)". Journal of Psychopharmacology 27 12 (2013): 1149-1159. http://dx.doi.org/10.1177/0269881113493363.
    Published • 10.1177/0269881113493363
  80. Roncon, Camila M; Biesdorf, Carla; Coimbra, Norberto C; Audi, Elisabeth A; Zangrossi, Hélio; Graeff, Frederico G. "Cooperative regulation of anxiety and panic-related defensive behaviors in the rat periaqueductal grey matter by 5-HT1A and µ-receptors". Journal of Psychopharmacology 27 12 (2013): 1141-1148. http://dx.doi.org/10.1177/0269881113485144.
    Published • 10.1177/0269881113485144
  81. de Freitas, Renato Leonardo; Bolognesi, Luana Iacovelo; Twardowschy, André; Corrêa, Fernando Morgan Aguiar; Sibson, Nicola R.; Coimbra, Norberto Cysne. "Neuroanatomical and neuropharmacological approaches to postictal antinociception-related prosencephalic neurons: the role of muscarinic and nicotinic cholinergic receptors". Brain and Behavior 3 3 (2013): 286-301. http://dx.doi.org/10.1002/brb3.105.
    Open access • Published • 10.1002/brb3.105
  82. Biagioni, Audrey Francisco; de Freitas, Renato Leonardo; da Silva, Juliana Almeida; de Oliveira, Rithiele Cristina; de Oliveira, Ricardo; Alves, Vani Maria; Coimbra, Norberto Cysne. "Serotonergic neural links from the dorsal raphe nucleus modulate defensive behaviours organised by the dorsomedial hypothalamus and the elaboration of fear-induced antinociception via locus coeruleus pathways". Neuropharmacology 67 (2013): 379-394. http://dx.doi.org/10.1016/j.neuropharm.2012.10.024.
    Published • 10.1016/j.neuropharm.2012.10.024
  83. da Silva, Luis Felipe Souza; Coimbra, Norberto Cysne; Menescal-de-Oliveira, Leda. "Rostral ventromedial medulla connections in Cavia porcellus and their relation with tonic immobility defensive behavior: A biotinylated dextran amine neurotracing study". Neuroscience Letters 535 (2013): 116-121. http://dx.doi.org/10.1016/j.neulet.2012.12.031.
    Published • 10.1016/j.neulet.2012.12.031
  84. de Freitas, R. L.; Salgado-Rohner, C. J.; Biagioni, A. F.; Medeiros, P.; Hallak, J. E. C.; Crippa, J. A. S.; Coimbra, N. C.. "NMDA and AMPA/Kainate Glutamatergic Receptors in the Prelimbic Medial Prefrontal Cortex Modulate the Elaborated Defensive Behavior and Innate Fear-Induced Antinociception Elicited by GABAA Receptor Blockade in the Medial Hypothalamus". Cerebral Cortex 24 6 (2013): 1518-1528. http://dx.doi.org/10.1093/cercor/bht001.
    Published • 10.1093/cercor/bht001
  85. da Silva, Juliana Almeida; de Freitas, Renato Leonardo; Eichenberger, Gustavo Cavalcanti Dutra; Maria Padovan, Cláudia; Cysne Coimbra, Norberto. "Chemical neuroanatomical and psychopharmacological evidence that ¿ receptor-mediated endogenous opioid peptide neurotransmission in the dorsal and ventral mesencephalon modulates panic-like behaviour". European Journal of Pharmacology 698 1-3 (2013): 235-245. http://dx.doi.org/10.1016/j.ejphar.2012.07.038.
    Open access • Published • 10.1016/j.ejphar.2012.07.038
  86. Spiacci, A.; Coimbra, N.C.; Zangrossi, H.. "Differential involvement of dorsal raphe subnuclei in the regulation of anxiety- and panic-related defensive behaviors". Neuroscience 227 (2012): 350-360. http://dx.doi.org/10.1016/j.neuroscience.2012.09.061.
    Published • 10.1016/j.neuroscience.2012.09.061
  87. da Silva, Luis Felipe Souza; Coimbra, Norberto Cysne; Menescal-de-Oliveira, Leda. "Rostral ventromedial medulla modulates nociception and tonic immobility behavior through connections with the A7 catecholaminergic region". Behavioural Brain Research 233 2 (2012): 422-427. http://dx.doi.org/10.1016/j.bbr.2012.05.020.
    Published • 10.1016/j.bbr.2012.05.020
  88. Lopes, Luana T.; Patrone, Luis G. A.; Bícego, Kênia C.; Coimbra, Norberto C.; Gargaglioni, Luciane H.. "Periaqueductal gray matter modulates the hypercapnic ventilatory response". Pflügers Archiv - European Journal of Physiology 464 2 (2012): 155-166. http://dx.doi.org/10.1007/s00424-012-1119-6.
    Published • 10.1007/s00424-012-1119-6
  89. Biagioni, A.F.; Silva, J.A.; Coimbra, N.C.. "Panic-like defensive behavior but not fear-induced antinociception is differently organized by dorsomedial and posterior hypothalamic nuclei of Rattus norvegicus (Rodentia, Muridae)". Brazilian Journal of Medical and Biological Research 45 4 (2012): 328-336. http://dx.doi.org/10.1590/s0100-879x2012007500037.
    Open access • Published • 10.1590/s0100-879x2012007500037
  90. de Freitas, Renato Leonardo; Kübler, João Marcus Lopes; Elias-Filho, Daoud Hibraim; Coimbra, Norberto Cysne. "Antinociception induced by acute oral administration of sweet substance in young and adult rodents: The role of endogenous opioid peptides chemical mediators and µ1-opioid receptors". Pharmacology Biochemistry and Behavior 101 2 (2012): 265-270. http://dx.doi.org/10.1016/j.pbb.2011.12.005.
    Published • 10.1016/j.pbb.2011.12.005
  91. Felippotti, Tatiana Tocchini; Freitas, Renato Leonardo de; Coimbra, Norberto Cysne. "Endogenous opioid peptide-mediated neurotransmission in central and pericentral nuclei of the inferior colliculus recruits µ1-opioid receptor to modulate post-ictal antinociception". Neuropeptides 46 1 (2012): 39-47. http://dx.doi.org/10.1016/j.npep.2011.10.001.
    Published • 10.1016/j.npep.2011.10.001
  92. de Araujo, Fernanda Lopes Buiatti; Bertolino, Guilherme; Gonçalves, Renata Batagini; Marini, Luana de Castro; Coimbra, Norberto Cysne; de Araujo, João Eduardo; Souza, Hugo Celso Dutra. "Neuropathology and behavioral impairments after three types of global ischemia surgery in Meriones unguiculatus: Evidence in motor cortex, hippocampal CA1 region and the neostriatum". Journal of the Neurological Sciences 312 1-2 (2012): 73-78. http://dx.doi.org/10.1016/j.jns.2011.08.019.
    Published • 10.1016/j.jns.2011.08.019
  93. Bassi, Gabriel S.; Kanashiro, Alexandre; Santin, Francele M.; de Souza, Glória E. P.; Nobre, Manoel J.; Coimbra, Norberto C.. "Lipopolysaccharide-Induced Sickness Behaviour Evaluated in Different Models of Anxiety and Innate Fear in Rats". Basic & Clinical Pharmacology & Toxicology 110 4 (2011): 359-369. http://dx.doi.org/10.1111/j.1742-7843.2011.00824.x.
    Published • 10.1111/j.1742-7843.2011.00824.x
  94. Felippotti, Tatiana Tocchini; Ribeiro do Carmo, Devaney; Paim, Leonardo Lataro; Stradiotto, Nelson Ramos; Bicalho, Urquisa de Oliveira; Parada, Carlos Amílcar; Grillo, Renato; Fraceto, Leonardo Fernandes; Coimbra, Norberto Cysne. "Effect of a nanostructured dendrimer-naloxonazine complex on endogenous opioid peptides µ1 receptor-mediated post-ictal antinociception". Nanomedicine: Nanotechnology, Biology and Medicine 7 6 (2011): 871-880. http://dx.doi.org/10.1016/j.nano.2011.02.005.
    10.1016/j.nano.2011.02.005
  95. de Oliveira, Rithiele Cristina; de Oliveira, Ricardo; Zanandréa, Priscila Cabrera; Paschoalin-Maurin, Tatiana; Coimbra, Norberto Cysne. "Acetylcholine-mediated neurotransmission within the nucleus raphe magnus exerts a key role in the organization of both interictal and postictal antinociception". Epilepsy & Behavior 22 2 (2011): 178-185. http://dx.doi.org/10.1016/j.yebeh.2011.06.029.
    Open access • Published • 10.1016/j.yebeh.2011.06.029
  96. Felippotti, Tatiana Tocchini; dos Reis Ferreira, Célio Marcos; de Freitas, Renato Leonardo; de Oliveira, Rithiele Cristina; de Oliveira, Ricardo; Paschoalin-Maurin, Tatiana; Coimbra, Norberto Cysne. "Paradoxical effect of noradrenaline-mediated neurotransmission in the antinociceptive phenomenon that accompanies tonic–clonic seizures: Role of locus coeruleus neurons and a2- and ß-noradrenergic receptors". Epilepsy & Behavior 22 2 (2011): 165-177. http://dx.doi.org/10.1016/j.yebeh.2011.06.028.
    Published • 10.1016/j.yebeh.2011.06.028
  97. Uribe-Mariño, Andrés; Francisco, Audrey; Castiblanco-Urbina, Maria Angélica; Twardowschy, André; Salgado-Rohner, Carlos José; Crippa, José Alexandre S; Hallak, Jaime Eduardo Cecílio; Zuardi, Antônio Waldo; Coimbra, Norberto Cysne. "Anti-Aversive Effects of Cannabidiol on Innate Fear-Induced Behaviors Evoked by an Ethological Model of Panic Attacks Based on a Prey vs the Wild Snake Epicrates cenchria crassus Confrontation Paradigm". Neuropsychopharmacology 37 2 (2011): 412-421. http://dx.doi.org/10.1038/npp.2011.188.
    Open access • Published • 10.1038/npp.2011.188
  98. Melo, L.L.; Santos, P.; Medeiros, P.; Mello, R.O.; Ferrari, E.A.M.; Brandão, M.L.; Maisonnette, S.S.; Francisco, A.; Coimbra, N.C.. "Glutamatergic neurotransmission mediated by NMDA receptors in the inferior colliculus can modulate haloperidol-induced catalepsy". Brain Research 1349 (2010): 41-47. http://dx.doi.org/10.1016/j.brainres.2010.06.020.
    Published • 10.1016/j.brainres.2010.06.020
  99. dos Reis Ferreira, Célio Marcos; CARDOSO, V.R.; VASCONCELLOS, T.H.F.; TEIXEIRA, D.G.; COIMBRA, N.C.; COUTO, L.B. . Corresponding author: dos Reis Ferreira, Célio Marcos. "Efeitos do Ultrassom Associado ao Stryphnodendron polyphylum M. em Lesão Cirúrgica em Ratos". Revista Mineira de Ciências da Saúde 2 (2010): 11-20.
    Published
  100. Freitas, Renato Leonardo; Uribe-Mariño, Andrés; Castiblanco-Urbina, Maria Angélica; Elias-Filho, Daoud Hibraim; Coimbra, Norberto Cysne. "GABAA receptor blockade in dorsomedial and ventromedial nuclei of the hypothalamus evokes panic-like elaborated defensive behaviour followed by innate fear-induced antinociception". Brain Research 1305 (2009): 118-131. http://dx.doi.org/10.1016/j.brainres.2009.09.096.
    Published • 10.1016/j.brainres.2009.09.096
  101. Freitas, Renato Leonardo; Ferreira, Célio Marcos dos Reis; Urbina, Maria Angélica Castiblanco; Mariño, Andrés Uribe; Carvalho, Andressa Daiane; Butera, Giuseppe; de Oliveira, Ana Maria; Coimbra, Norberto Cysne. "5-HT1A/1B, 5-HT6, and 5-HT7 serotonergic receptors recruitment in tonic-clonic seizure-induced antinociception: Role of dorsal raphe nucleus". Experimental Neurology 217 1 (2009): 16-24. http://dx.doi.org/10.1016/j.expneurol.2009.01.003.
    Published • 10.1016/j.expneurol.2009.01.003
  102. Melo, Liana L.; Pereira, Ellen C.H.M.; Pagini, Cássia H.; Coimbra, Norberto C.; Brandão, Marcus L.; Ferrari, Elenice A.M.. "Effects of microinjections of apomorphine and haloperidol into the inferior colliculus on the latent inhibition of the conditioned emotional response". Experimental Neurology 216 1 (2009): 16-21. http://dx.doi.org/10.1016/j.expneurol.2008.10.020.
    Published • 10.1016/j.expneurol.2008.10.020
  103. Lobão-Soares, Bruno; Walz, Roger; Prediger, Rui Daniel Schröder; Freitas, Renato Leonardo; Calvo, Fabrício; Bianchin, Marino Muxfeldt; Leite, João Pereira; Landemberger, Michele Christine; Coimbra, Norberto Cysne. "Cellular prion protein modulates defensive attention and innate fear-induced behaviour evoked in transgenic mice submitted to an agonistic encounter with the tropical coral snake Oxyrhopus guibei". Behavioural Brain Research 194 2 (2008): 129-137. http://dx.doi.org/10.1016/j.bbr.2008.06.006.
    Published • 10.1016/j.bbr.2008.06.006
  104. Freitas, Renato Leonardo; Bassi, Gabriel Shimizu; de Oliveira, Ana Maria; Coimbra, Norberto Cysne. "Serotonergic neurotransmission in the dorsal raphe nucleus recruits in situ 5-HT2A/2C receptors to modulate the post-ictal antinociception". Experimental Neurology 213 2 (2008): 410-418. http://dx.doi.org/10.1016/j.expneurol.2008.07.003.
    Published • 10.1016/j.expneurol.2008.07.003
  105. de Araujo, Fernanda Lopes Buiatti; Bertolino, Guilherme; Funayama, Carolina Araújo Rodrigues; Coimbra, Norberto Cysne; de Araujo, João Eduardo. "Influence of treadmill training on motor performance and organization of exploratory behavior in Meriones unguiculatus with unilateral ischemic stroke: Histological correlates in hippocampal CA1 region and the neostriatum". Neuroscience Letters 431 2 (2008): 179-183. http://dx.doi.org/10.1016/j.neulet.2007.11.038.
    Published • 10.1016/j.neulet.2007.11.038
  106. Silva, Manoel Nunes da; Colli, Benedicto Oscar; Coimbra, Norberto Cysne; Coutinho Netto, Joaquim. "Evaluation of the neuroprotective effect of ketoprofen on rats submitted to permanent focal brain ischemia". Arquivos de Neuro-Psiquiatria 65 4a (2007): 978-984. http://dx.doi.org/10.1590/s0004-282x2007000600011.
    Open access • Published • 10.1590/s0004-282x2007000600011
  107. LOBAOSOARES, B; WALZ, R; CARLOTTIJR, C; SAKAMOTO, A; CALVO, F; TERZIAN, A; SILVA, J; et al. "Cellular prion protein regulates the motor behaviour performance and anxiety-induced responses in genetically modified mice". Behavioural Brain Research 183 1 (2007): 87-94. http://dx.doi.org/10.1016/j.bbr.2007.05.027.
    Published • 10.1016/j.bbr.2007.05.027
  108. Guimarães-Costa, Raquel; Guimarães-Costa, Maria Beatriz; Pippa-Gadioli, Leonardo; Weltson, Alfredo; Ubiali, Walter Adriano; Paschoalin-Maurin, Tatiana; Felippotti, Tatiana Tocchini; et al. "Innate defensive behaviour and panic-like reactions evoked by rodents during aggressive encounters with Brazilian constrictor snakes in a complex labyrinth: Behavioural validation of a new model to study affective and agonistic reactions in a prey versus predator paradigm". Journal of Neuroscience Methods 165 1 (2007): 25-37. http://dx.doi.org/10.1016/j.jneumeth.2007.05.023.
    Published • 10.1016/j.jneumeth.2007.05.023
  109. Mortari, M R; Cunha, A O S; Carolino, R O G; Coutinho-Netto, J; Tomaz, J C; Lopes, N P; Coimbra, N C; dos Santos, W F. "Inhibition of acute nociceptive responses in rats after i.c.v. injection of Thr6 -bradykinin, isolated from the venom of the social wasp, Polybia occidentalis". British Journal of Pharmacology 151 6 (2007): 860-869. http://dx.doi.org/10.1038/sj.bjp.0707275.
    Open access • Published • 10.1038/sj.bjp.0707275
  110. de Oliveira, Rithiele Cristina; de Oliveira, Ricardo; Ferreira, Célio Marcos dos Reis; Coimbra, Norberto Cysne. "Involvement of 5-HT2 serotonergic receptors of the nucleus raphe magnus and nucleus reticularis gigantocellularis/paragigantocellularis complex neural networks in the antinociceptive phenomenon that follows the post-ictal immobility syndrome". Experimental Neurology 201 1 (2006): 144-153. http://dx.doi.org/10.1016/j.expneurol.2006.03.033.
    Published • 10.1016/j.expneurol.2006.03.033
  111. Castellan-Baldan, Lissandra; da Costa Kawasaki, Mateus; Ribeiro, Sandro José; Calvo, Fabrício; Corrêa, Vani Maria Alves; Coimbra, Norberto Cysne. "Topographic and functional neuroanatomical study of GABAergic disinhibitory striatum–nigral inputs and inhibitory nigrocollicular pathways: Neural hodology recruiting the substantia nigra, pars reticulata, for the modulation of the neural activity in the inferior colliculus involved with panic-like emotions". Journal of Chemical Neuroanatomy 32 1 (2006): 1-27. http://dx.doi.org/10.1016/j.jchemneu.2006.05.002.
    Published • 10.1016/j.jchemneu.2006.05.002
  112. Calvo, Fabrício; Coimbra, Norberto Cysne. "Interactions between opioid-peptides-containing pathways and GABAA-receptors-mediated systems modulate panic-like-induced behaviors elicited by electric and chemical stimulation of the inferior colliculus". Brain Research 1104 1 (2006): 92-102. http://dx.doi.org/10.1016/j.brainres.2006.05.056.
    Published • 10.1016/j.brainres.2006.05.056
  113. Couto, Lucélio Bernardes; Moroni, Cristian Rogério; Ferreira, Célio Marcos dos Reis; Elias-Filho, Daoud Hibrahim; Parada, Carlos Amílcar; Pelá, Irene Rosemir; Coimbra, Norberto Cysne. "Descriptive and functional neuroanatomy of locus coeruleus-noradrenaline-containing neurons involvement in bradykinin-induced antinociception on principal sensory trigeminal nucleus". Journal of Chemical Neuroanatomy 32 1 (2006): 28-45. http://dx.doi.org/10.1016/j.jchemneu.2006.03.003.
    Published • 10.1016/j.jchemneu.2006.03.003
  114. de Oliveira, Luciana; Cunha, Alexandra Olímpio Siqueira; Mortari, Márcia Renata; Coimbra, Norberto Cysne; Dos Santos, Wagner Ferreira. "Cataleptic activity of the denatured venom of the social wasp Agelaia vicina (Hymenoptera, Vespidae) in Rattus norvegicus (Rodentia, Muridae)". Progress in Neuro-Psychopharmacology and Biological Psychiatry 30 2 (2006): 198-203. http://dx.doi.org/10.1016/j.pnpbp.2005.10.016.
    Published • 10.1016/j.pnpbp.2005.10.016
  115. Kishi, Renato; Bongiovanni, Renata; de Nadai, Tales Rubens; Freitas, Renato Leonardo; de Oliveira, Ricardo; Ferreira, Célio Marcos dos Reis; Coimbra, Norberto Cysne. "Dorsal raphe nucleus and locus coeruleus neural networks and the elaboration of the sweet-substance-induced antinociception". Neuroscience Letters 395 1 (2006): 12-17. http://dx.doi.org/10.1016/j.neulet.2005.10.046.
    Published • 10.1016/j.neulet.2005.10.046
  116. Coimbra, N.C.; De Oliveira, R.; Freitas, R.L.; Ribeiro, S.J.; Borelli, K.G.; Pacagnella, R.C.; Moreira, J.E.; et al. "Neuroanatomical approaches of the tectum-reticular pathways and immunohistochemical evidence for serotonin-positive perikarya on neuronal substrates of the superior colliculus and periaqueductal gray matter involved in the elaboration of the defensive behavior and fear-induced analgesia". Experimental Neurology 197 1 (2006): 93-112. http://dx.doi.org/10.1016/j.expneurol.2005.08.022.
    Published • 10.1016/j.expneurol.2005.08.022
  117. Ribeiro, S.J.; Ciscato, J.G.; de Oliveira, R.; de Oliveira, R.C.; D’Ângelo-Dias, R.; Carvalho, A.D.; Felippotti, T.T.; et al. "Functional and ultrastructural neuroanatomy of interactive intratectal/tectonigral mesencephalic opioid inhibitory links and nigrotectal GABAergic pathways: Involvement of GABAA and µ1-opioid receptors in the modulation of panic-like reactions elicited by electrical stimulation of the dorsal midbrain". Journal of Chemical Neuroanatomy 30 4 (2005): 184-200. http://dx.doi.org/10.1016/j.jchemneu.2005.07.004.
    Published • 10.1016/j.jchemneu.2005.07.004
  118. Borelli, Karina Genaro; Ferreira-Netto, Cristina; Coimbra, Norberto Cysne; Brandão, Marcus Lira. "Fos-like immunoreactivity in the brain associated with freezing or escape induced by inhibition of either glutamic acid decarboxylase or GABAA receptors in the dorsal periaqueductal gray". Brain Research 1051 1-2 (2005): 100-111. http://dx.doi.org/10.1016/j.brainres.2005.05.068.
    Published • 10.1016/j.brainres.2005.05.068
  119. Miyase, Cátia Isumi; Kishi, Renato; de Freitas, Renato Leonardo; Paz, Denise Amorim; Coimbra, Norberto Cysne. "Involvement of pre- and post-synaptic serotonergic receptors of dorsal raphe nucleus neural network in the control of the sweet-substance-induced analgesia in adult Rattus norvegicus (Rodentia, Muridae)". Neuroscience Letters 379 3 (2005): 169-173. http://dx.doi.org/10.1016/j.neulet.2004.12.058.
    Published • 10.1016/j.neulet.2004.12.058
  120. Segato, E.N.; Rebouças, E.C.C.; Freitas, R.L.; Caires, M.P.T.; Cardoso, A.V.; Resende, G.C.C.; Shimizu-Bassi, G.; Elias-Filho, D.H.; Coimbra, N.C.. "Effect of chronic intake of sweet substance on nociceptive thresholds and feeding behavior of Rattus norvegicus (Rodentia, Muridae)". Nutritional Neuroscience 8 2 (2005): 129-140. http://dx.doi.org/10.1080/10284150500069413.
    Published • 10.1080/10284150500069413
  121. FREITAS, R; FERREIRA, C; RIBEIRO, S; CARVALHO, A; ELIASFILHO, D; GARCIACAIRASCO, N; COIMBRA, N. "Intrinsic neural circuits between dorsal midbrain neurons that control fear-induced responses and seizure activity and nuclei of the pain inhibitory system elaborating postictal antinociceptive processes: a functional neuroanatomical and neuropharmacological study". Experimental Neurology 191 2 (2005): 225-242. http://dx.doi.org/10.1016/j.expneurol.2004.10.009.
    Published • 10.1016/j.expneurol.2004.10.009
  122. de Oliveira, Luciana; Cunha, Alexandra Olimpio Siqueira; Mortari, Márcia Renata; Pizzo, Andréa Baldocchi; Miranda, Antonio; Coimbra, Norberto Cysne; dos Santos, Wagner Ferreira. "Effects of microinjections of neurotoxin AvTx8, isolated from the social wasp Agelaia vicina (Hymenoptera, Vespidae) venom, on GABAergic nigrotectal pathways". Brain Research 1031 1 (2005): 74-81. http://dx.doi.org/10.1016/j.brainres.2004.10.027.
    Published • 10.1016/j.brainres.2004.10.027
  123. Rebou¿as, E. C. C.; Segato, E. N.; Kishi, R.; Freitas, R. L.; Savoldi, M.; Morato, S.; Coimbra, N. C.. "Effect of the blockade of ?1-opioid and 5HT2A-serotonergic/?1-noradrenergic receptors on sweet-substance-induced analgesia". Psychopharmacology 179 2 (2004): 349-355. http://dx.doi.org/10.1007/s00213-004-2045-x.
    Published • 10.1007/s00213-004-2045-x
  124. Beleboni, Renê Oliveira; Carolino, Ruither Oliveira Gomes; Pizzo, Andrea Baldocchi; Castellan-Baldan, Lissandra; Coutinho-Netto, Joaquim; dos Santos, Wagner Ferreira; Coimbra, Norberto Cysne. "Pharmacological and Biochemical Aspects of GABAergic Neurotransmission: Pathological and Neuropsychobiological Relationships". Cellular and Molecular Neurobiology 24 6 (2004): 707-728. http://dx.doi.org/10.1007/s10571-004-6913-z.
    Published • 10.1007/s10571-004-6913-z
  125. de Freitas, Renato Leonardo; de Oliveira, Rithiele Cristina; de Carvalho, Andressa Daiane; Felippotti, Tatiana Tocchini; Bassi, Gabriel Shimizu; Elias-Filho, Daoud Hibrahim; Coimbra, Norberto Cysne. "Role of muscarinic and nicotinic cholinergic receptors in an experimental model of epilepsy-induced analgesia". Pharmacology Biochemistry and Behavior 79 2 (2004): 367-376. http://dx.doi.org/10.1016/j.pbb.2004.08.007.
    Published • 10.1016/j.pbb.2004.08.007
  126. Almeida, Maria C.; Steiner, Alexandre A.; Coimbra, Norberto C.; Branco, Luiz G. S.. "Thermoeffector neuronal pathways in fever: a study in rats showing a new role of the locus coeruleus". The Journal of Physiology 558 1 (2004): 283-294. http://dx.doi.org/10.1113/jphysiol.2004.066654.
    Open access • Published • 10.1113/jphysiol.2004.066654
  127. Borelli, Karina Genaro; Nobre, Manoel Jorge; Brandão, Marcus Lira; Coimbra, Norberto Cysne. "Effects of acute and chronic fluoxetine and diazepam on freezing behavior induced by electrical stimulation of dorsolateral and lateral columns of the periaqueductal gray matter". Pharmacology Biochemistry and Behavior 77 3 (2004): 557-566. http://dx.doi.org/10.1016/j.pbb.2003.12.009.
    Published • 10.1016/j.pbb.2003.12.009
  128. Osaki, M.Y; Castellan-Baldan, L; Calvo, F; Carvalho, A.D; Felippotti, T.T; de Oliveira, R; Ubiali, W.A; et al. "Neuroanatomical and neuropharmacological study of opioid pathways in the mesencephalic tectum: effect of µ1- and ¿-opioid receptor blockade on escape behavior induced by electrical stimulation of the inferior colliculus". Brain Research 992 2 (2003): 179-192. http://dx.doi.org/10.1016/j.brainres.2003.08.040.
    Published • 10.1016/j.brainres.2003.08.040
  129. Fontana, Andréia Cristina Karklin; Guizzo, Renato; Beleboni, Renê de Oliveira; Meirelles e Silva, Antonio Renato; Coimbra, Norberto Cysne; Amara, Susan G; Santos, Wagner Ferreira dos; Coutinho-Netto, Joaquim. "Purification of a neuroprotective component ofParawixia bistriataspider venom that enhances glutamate uptake". British Journal of Pharmacology 139 7 (2003): 1297-1309. http://dx.doi.org/10.1038/sj.bjp.0705352.
    Published • 10.1038/sj.bjp.0705352
  130. Gargaglioni, Luciane H; Coimbra, Norberto C; Branco, Luiz G.S. "The nucleus raphe magnus modulates hypoxia-induced hyperventilation but not anapyrexia in rats". Neuroscience Letters 347 2 (2003): 121-125. http://dx.doi.org/10.1016/s0304-3940(03)00671-2.
    Published • 10.1016/s0304-3940(03)00671-2
  131. Leite-Panissi, Christie Ramos Andrade; Coimbra, Norberto Cysne; Menescal-de-Oliveira, Leda. "The cholinergic stimulation of the central amygdala modifying the tonic immobility response and antinociception in guinea pigs depends on the ventrolateral periaqueductal gray". Brain Research Bulletin 60 1-2 (2003): 167-178. http://dx.doi.org/10.1016/s0361-9230(03)00031-5.
    Published • 10.1016/s0361-9230(03)00031-5
  132. Strauss, C. "Effects of N-methyl-?-aspartate-induced amygdala lesion in rats submitted to the elevated T-maze test of anxiety". Physiology & Behavior 78 1 (2003): 157-163. http://dx.doi.org/10.1016/s0031-9384(02)00960-5.
    Published • 10.1016/s0031-9384(02)00960-5
  133. Netto, Sueli Mendonça; Silveira, Rodolfo; Coimbra, Norberto Cysne; Joca, Sâmia Regiane Lourenço; Guimarães, Francisco Silveira. "Anxiogenic effect of median raphe nucleus lesion in stressed rats". Progress in Neuro-Psychopharmacology and Biological Psychiatry 26 6 (2002): 1135-1141. http://dx.doi.org/10.1016/s0278-5846(02)00248-8.
    Published • 10.1016/s0278-5846(02)00248-8
  134. Gargaglioni, Luciane H; Coimbra, Norberto C; Branco, L.G.S. "Chemical lesions of the nucleus isthmi increase the hypoxic and hypercarbic drive to breathing of toads". Respiratory Physiology & Neurobiology 132 3 (2002): 289-299. http://dx.doi.org/10.1016/s1569-9048(02)00116-7.
    Published • 10.1016/s1569-9048(02)00116-7
  135. Eichenberger, G.C.D; Ribeiro, S.J; Osaki, M.Y; Maruoka, R.Y; Resende, G.C.C; Castellan-Baldan, L; Corrêa, S.A.L; Da Silva, L.A; Coimbra, N.C. "Neuroanatomical and psychopharmacological evidence for interaction between opioid and GABAergic neural pathways in the modulation of fear and defense elicited by electrical and chemical stimulation of the deep layers of the superior colliculus and dorsal periaqueductal gray matter". Neuropharmacology 42 1 (2002): 48-59. http://dx.doi.org/10.1016/s0028-3908(01)00155-1.
    Published • 10.1016/s0028-3908(01)00155-1
  136. Coimbra, N.C.; Freitas, R.L.; Savoldi, M.; Castro-Souza, C.; Segato, E.N.; Kishi, R.; Weltson, A.; Resende, G.C.C.. "Opioid neurotransmission in the post-ictal analgesia: Involvement of µ1-opioid receptor". Brain Research 903 1-2 (2001): 216-221. http://dx.doi.org/10.1016/s0006-8993(01)02366-6.
    Published • 10.1016/s0006-8993(01)02366-6
  137. Irusta, A.E.C; Savoldi, M; Kishi, R; Resende, G.C.C; Freitas, R.L; Carvalho, A.D; Coimbra, N.C. "Psychopharmacological evidences for the involvement of muscarinic and nicotinic cholinergic receptors on sweet substance-induced analgesia in Rattus norvegicus". Neuroscience Letters 305 2 (2001): 115-118. http://dx.doi.org/10.1016/s0304-3940(01)01824-9.
    Published • 10.1016/s0304-3940(01)01824-9
  138. Brandão, Marcus Lira; Coimbra, Norberto C; Osaki, Mário Yukio. "Changes in the auditory-evoked potentials induced by fear-evoking stimulations". Physiology & Behavior 72 3 (2001): 365-372. http://dx.doi.org/10.1016/s0031-9384(00)00418-2.
    Published • 10.1016/s0031-9384(00)00418-2
  139. Coimbra, N.C; Castro-Souza, C; Segato, E.N; Nora, J.E.P; Herrero, C.F.P.S; Tedeschi-Filho, W; Garcia-Cairasco, N. "Post-ictal analgesia: involvement of opioid, serotoninergic and cholinergic mechanisms". Brain Research 888 2 (2001): 314-320. http://dx.doi.org/10.1016/s0006-8993(00)03103-6.
    Published • 10.1016/s0006-8993(00)03103-6
  140. Coimbra, N.C.; Osaki, M.Y.; Eichenberger, G.C.D.; Ciscato Jr, J.G.; Jucá, C.E.B.; Biojone, C.R.. "Effects of opioid receptor blockade on defensive behavior elicited by electrical stimulation of the aversive substrates of the inferior colliculus in Rattus norvegicus ( Rodentia , Muridae )". Psychopharmacology 152 4 (2000): 422-430. http://dx.doi.org/10.1007/s002130000544.
    Published • 10.1007/s002130000544
  141. Anseloni, Vanessa C. Z.; Coimbra, Norberto C.; Morato, S.; Brandão, M. L.. "A comparative study of the effects of morphine in the dorsal periaqueductal gray and nucleus accumbens of rats submitted to the elevated plus-maze test". Experimental Brain Research 129 2 (1999): 260-268. http://dx.doi.org/10.1007/s002210050896.
    Published • 10.1007/s002210050896
  142. Mamede Rosa, Maria Luiza N; Oliveira, Marina A; Valente, Rodrigo B; Coimbra, Norberto C; Prado, Wiliam A. "Pharmacological and neuroanatomical evidence for the involvement of the anterior pretectal nucleus in the antinociception induced by stimulation of the dorsal raphe nucleus in rats". Pain 74 2 (1998): 171-179. http://dx.doi.org/10.1016/s0304-3959(97)00175-9.
    Published • 10.1016/s0304-3959(97)00175-9
  143. Segato, F.N.; Castro-Souza, C.; Segato, E.N.; Morato, S.; Coimbra, N.C.. "Sucrose ingestion causes opioid analgesia". Brazilian Journal of Medical and Biological Research 30 8 (1997): 981-984. http://dx.doi.org/10.1590/s0100-879x1997000800011.
    Open access • Published • 10.1590/s0100-879x1997000800011
  144. Coimbra, N.C; Brandão, M.L. "Effects of 5-HT2 receptors blockade on fear-induced analgesia elicited by electrical stimulation of the deep layers of the superior colliculus and dorsal periaqueductal gray". Behavioural Brain Research 87 1 (1997): 97-103. http://dx.doi.org/10.1016/s0166-4328(96)02267-x.
    Published • 10.1016/s0166-4328(96)02267-x
  145. Coimbra, N.C.; Eichenberger, G.C.D.; Gorchinski, R.T.; Maisonnette, S.. "Effects of the blockade of opioid receptor on defensive reactions elicited by electrical stimulation within the deep layers of the superior colliculus and DPAG". Brain Research 736 1-2 (1996): 348-352. http://dx.doi.org/10.1016/0006-8993(96)00928-6.
    Published • 10.1016/0006-8993(96)00928-6
  146. Maisonnette, Silvia S.; Kawasaki, Mateus C.; Coimbra, Norberto C.; Brandao, Marcus L.. "Effects of lesions of amygdaloid nuclei and substantia nigra on aversive responses induced by electrical stimulation of the inferior colliculus". Brain Research Bulletin 40 2 (1996): 93-98. http://dx.doi.org/10.1016/0361-9230(95)02136-1.
    Published • 10.1016/0361-9230(95)02136-1
  147. Eichenberger, Gustavo Cavalvcanti Dutra; da Silva, Luís Antônio; Chiericato Jr., Glaico; Coimbra, Norberto Cysne. "Analysis of the performance of microelectrodes by cyclic and differential pulse voltammetry tecniques". Bioelectrochemistry and Bioenergetics 38 2 (1995): 315-319.
    Published
  148. Brandão, M.L.; Cardoso, S.H.; Melo, L.L.; Motta, V.; Coimbra, N.C.. "Neural substrate of defensive behavior in the midbrain tectum". Neuroscience & Biobehavioral Reviews 18 3 (1994): 339-346. http://dx.doi.org/10.1016/0149-7634(94)90047-7.
    Published • 10.1016/0149-7634(94)90047-7
  149. Cardoso, Silvia Helena; Coimbra, Norberto Cysne; Brandão, Marcus Lira. "Defensive reactions evoked by activation of NMDA receptors in distinct sites of the inferior colliculus". Behavioural Brain Research 63 1 (1994): 17-24. http://dx.doi.org/10.1016/0166-4328(94)90046-9.
    Published • 10.1016/0166-4328(94)90046-9
  150. Coimbra, Norberto Cysne; Brandão, Marcus Lira. "GABAergic nigro-collicular pathways modulate the defensive behaviour elicited by midbrain tectum stimulation". Behavioural Brain Research 59 1-2 (1993): 131-139. http://dx.doi.org/10.1016/0166-4328(93)90159-n.
    Published • 10.1016/0166-4328(93)90159-n
  151. "Opposite effects of low and high doses of morphine on neural substrates of aversion in the inferior colliculus". Behavioural Pharmacology 3 5 (1992): 489-495.
    Published
  152. Brandao, M.L.; Coimbra, N.C.; Borges, P.C. Leao. "Effects of morphine and midazolam on reactivity to peripheral noxious and central aversive stimuli". Neuroscience & Biobehavioral Reviews 14 4 (1990): 495-499. http://dx.doi.org/10.1016/s0149-7634(05)80073-9.
    Published • 10.1016/s0149-7634(05)80073-9
  153. "GABAergic fibers from substantia nigra pars reticulata modulate escape behavior induced by midbrain central gray stimulation". Brazilian Journal of Medical and Biological Research 22 1 (1989): 111-114.
    Open access • Published
  154. Brandão, M.L.; Tomaz, C.; Leão Borges, P.C.; Coimbra, N.C.; Bagri, A.. "Defense reaction induced by microinjections of bicuculline into the inferior colliculus". Physiology & Behavior 44 3 (1988): 361-365. http://dx.doi.org/10.1016/0031-9384(88)90038-8.
    Published • 10.1016/0031-9384(88)90038-8
  155. "Independence of aversive and pain mechanisms in the dorsal periaqueductal gray matter of the rat". Brazilian Journal of Medical and Biological Research 21 5 (1988): 1027-1031.
    Published

Other

Other output
  1. Role of education after the COVID-19 pandemic fear: a multidisciplinary and scientific perspective. 2020. Monica Naves-Barcelos; Priscila Medeiros; Carla Benedita da Silva Tostes; Juliana Almeida da Silva; Josie Resende Torres da Silva; Jorge Gelvane Tostes; José Aparecido da Silva; et al. https://doi.org/10.1590/SciELOPreprints.710.
    10.1590/SciELOPreprints.710
  2. Preparing for the COVID-19 Mental Health Crisis in Latin America – Using Early Evidence From Countries That Experienced COVID-19 First. 2020. Alberto Abad; Juliana Almeida Da Silva; João Vitor Zamana das Neves Braga; Priscila Medeiros; Renato Leonardo De Freitas; Norberto Cysne Coimbra; José Aparecido Da Silva. https://doi.org/10.20944/preprints202005.0018.v1.
    10.20944/preprints202005.0018.v1
Distinctions

Title

1995 Scientiae Doctor (Morfologia-Biologia Celular)
Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo, Brazil
1991 Magister Scientiae cum laude (Psicobiologia)
Faculdade de Filosofia, Ciências e Letras da Universidade de São Paulo , Brazil

Other distinction

2006 Pós-Doutorado
University of Oxford, United Kingdom