???global.info.a_carregar???
Joana Rodrigues. Completed the PhD in Genetics and Microbiology in 2017/08/30 by Newcastle University, Institute for Cell and Molecular Biosciences, the Masters in Molecular and Cellular Biology in 2012 by Universidade de Coimbra Faculdade de Ciencias e Tecnologia and a Degree in Biotechnology in 2009 by Instituto Politécnico de Coimbra Escola Superior Agrária de Coimbra.
Identification

Personal identification

Full name
Joana Rodrigues

Citation names

  • Rodrigues, Joana

Author identifiers

Ciência ID
571D-942F-D038
ORCID iD
0000-0002-3263-3887

Email addresses

  • joana.rodrigues@medicina.ulisboa.pt (Professional)

Knowledge fields

  • Natural sciences - Biological Sciences - Molecular Biology

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Advanced (C1) Proficiency (C2) Proficiency (C2) Proficiency (C2) Advanced (C1)
Education
Degree Classification
2013/05/01 - 2017/08/30
Concluded
 Genetics and Microbiology (Doutoramento)
Newcastle University Institute for Cell and Molecular Biosciences, United Kingdom
"YEAST GENOME-WIDE TELOMERE SCREENS AND INSIGHTS INTO CANCER" (THESIS/DISSERTATION)
2012
Concluded
 Masters in Molecular and Cellular Biology (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Pyruvate dehydrogenase and mitochondrial function in Huntington’s disease models – influence of histone deacetylase inhibitors" (THESIS/DISSERTATION)
 18
2009
Concluded
 Degree in Biotechnology (Licenciatura)
Instituto Politécnico de Coimbra Escola Superior Agrária de Coimbra, Portugal
"Controlo da forma celular em Bacillus subtilis: super-produção, purificação e análise dos domínios citoplasmático e extra-celular da proteína morfogénica RodZ" (THESIS/DISSERTATION)
 16
Affiliation

Science

Category
Host institution 		Employer
2018/11/01 - Current Postdoc (Research) Instituto de Medicina Molecular, Portugal
Instituto de Medicina Molecular, Portugal
2017/09/01 - 2018/03/31 Research Assistant (Research) Newcastle University Institute for Cell and Molecular Biosciences, United Kingdom
Newcastle University Institute for Cell and Molecular Biosciences, United Kingdom
2013/05/01 - 2017/08/30 Researcher (Research) Newcastle University Institute for Cell and Molecular Biosciences, United Kingdom
Newcastle University Institute for Cell and Molecular Biosciences, United Kingdom
2011/09/01 - 2012/07/31 Research Trainee (Research) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2009/06/01 - 2010/06/30 Research Trainee (Research) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
Projects

Grant

Designation Funders
2013/05/01 - 2016/05/30 The role of Chronic DNA damage in Ageing and Age-related pathology
info:eu-repo/grantAgreement/EC/FP7/316354/EU
PhD Student Fellow
Newcastle University, United Kingdom
 European Commission
Concluded
2010/01/15 - 2010/06/15 Estudo da oligomerização dos domínios citoplasmático e extra-celular da proteína morfogénica RodZ
082/BI/2009
Scientific Initiation Fellow
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded

Contract

Designation Funders
2018/10/01 - Current TERRA and telomerase­-mediated telomere elongation: unveiling novel molecular pathways towards the development of innovative therapeutic approaches for cancer treatment.  
C490695865-00081628
Post-doc Fellow
Instituto de Medicina Molecular, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2021/03/29 - 2024/06/30 Assembly and functions of the mammalian telomeric deoxyribo/ribonucleoprotein particle at chromosome ends and beyond
PTDC/BIA-MOL/6624/2020
Post-doc
Outputs

Publications

Journal article
  1. Joana Rodrigues; Peter Banks; David Lydall. "Vps74 Connects the Golgi Apparatus and Telomeres in Saccharomyces cerevisiae". G3: Genes|Genomes|Genetics 8 5 (2018): 1807-1816. https://doi.org/10.1534/g3.118.200172.
    10.1534/g3.118.200172
  2. Rodrigues J; Lydall D. "Cis and trans interactions between genes encoding PAF1 complex and ESCRT machinery components in yeast.". Current genetics (2018): http://europepmc.org/abstract/med/29564528.
    10.1007/s00294-018-0828-6
  3. Rodrigues J; Lydall D. "Paf1 and Ctr9, core components of the PAF1 complex, maintain low levels of telomeric repeat containing RNA.". Nucleic acids research (2018): http://europepmc.org/abstract/med/29145644.
    10.1093/nar/gkx1131
  4. Luana Naia; Teresa Cunha-Oliveira; Joana Rodrigues; Tatiana R. Rosenstock; Ana Oliveira; Márcio Ribeiro; Catarina Carmo; et al. "Histone Deacetylase Inhibitors Protect Against Pyruvate Dehydrogenase Dysfunction in Huntington's Disease". The Journal of Neuroscience 37 10 (2017): 2776-2794. https://doi.org/10.1523%2Fjneurosci.2006-14.2016.
    10.1523/JNEUROSCI.2006-14.2016
  5. Naia L; Ribeiro M; Rodrigues J; Duarte AI; Lopes C; Rosenstock TR; Hayden MR; Rego AC. "Insulin and IGF-1 regularize energy metabolites in neural cells expressing full-length mutant huntingtin.". (2016): http://europepmc.org/abstract/med/26876526.
    10.1016/j.npep.2016.01.009
  6. Silva A; Naia L; Dominguez A; Ribeiro M; Rodrigues J; Vieira OV; Lessmann V; Rego AC. "Overexpression of BDNF and Full-Length TrkB Receptor Ameliorate Striatal Neural Survival in Huntington's Disease.". (2015): http://europepmc.org/abstract/med/25896770.
    10.1159/000375447
  7. Ribeiro M; Silva AC; Rodrigues J; Naia L; Rego AC. "Oxidizing effects of exogenous stressors in Huntington's disease knock-in striatal cells--protective effect of cystamine and creatine.". (2013): http://europepmc.org/abstract/med/24008831.
    10.1093/toxsci/kft199
Preprint
  1. Joana Rodrigues; Roberta Alfieri; Silvia Bione; Claus M. Azzalin. "TERRA ONTseq: a long read-based sequencing pipeline to study the human telomeric transcriptome". 2023. https://doi.org/10.1101/2023.11.30.569384.
    10.1101/2023.11.30.569384
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2023/09/19 TERRA ONTseq: a long read-based sequencing pipeline to study the human telomeric transcriptome iMM Scientific Retreat
2016/05/17 PAF1 complex components regulate TERRA and telomere function in budding yeast Cell Division Biology Symposium
2016/03/04 Distinct roles for the PAF1 complex in TERRA and telomere function ICaMB Postgraduate Research Symposium, Newcastle.
2015/09/21 Telomeres and Ageging: From Yeast Genome wide screens to insights into cancer 3rd Joint CodeAge/ aDDRess/ Marriage Training Workshop on Genetic Model Organisms in Ageing Research
2015/03/26 Is there an adjacent gene effect between VPS36 and CDC73? The British Yeast Group Meeting
Manchester Institute of Biotechnology (MIB) (Manchester, United Kingdom)
2014/06/09 Cell Division - From Yeast Genome wide screens to insights into cancer 2nd CodeAge Training Workshop on "Regulation of the (Epi) Genome during Ageing"
(Crete, Greece)
2013/11/22 Cell Division: From Yeast Genome wide screens to insights into cancer 1st CodeAge Annual Meeting and Workshop on DNA damage, chromatin and aging
(Milan, Italy)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2017/06/12 - 2017/08/04 Investigation of the role of Vps74 in telomere biology
Co-supervisor
2016/01/04 - 2016/03/11 Mechanisms that affect fitness of cells with telomere defects
Co-supervisor
2015/01/05 - 2015/03/03 Investigating the role of UBP6 and CKA2 genes at uncapped telomeres in Saccharomyces cerevisiae
Co-supervisor

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2023/01/26 - 2023/01/27 Poster presentation
Conference
 IX ptRNA joint meeting
2022/09/26 - 2022/09/29 Poster presentation
Workshop
 EMBO workshop ‘Telomere function and evolution in health and disease’
2022/07/12 - 2022/07/12 Poster presentation
Conference
 RiboMed Satellite Conference on RNA in Disease
2017/05/02 - 2017/05/06 Poster presentation
Meeting
 Cold Spring Harbor meeting on Telomeres & Telomerase
2016/04/03 - 2016/04/05 Poster presentation
Conference
 2nd Cologne Ageing Conference
2015/12/07 - 2015/12/10 Poster presentation
Workshop
 Telomeric chromatin and telomere fragility
2015/09/23 - 2015/09/23 Attendee
Workshop
 CodeAge Complementary Skills Workshop on Scholarly Publishing & Writing
2013/10/11 - 2013/10/11 Attendee
Round table
 North East Fungal Forum
2012/03/10 - 2012/03/10 Poster presentation
Meeting
 26a Reunião do Grupo de Estudo de Envelhecimento Cerebral e Demências
2012/01/14 - 2012/01/14 Poster presentation
Workshop
 V Workshop Bioquímica

Mentoring / Tutoring

Topic Student name
2024/01/04 - 2024/01/26 Generation of novel tools to increase telomere transcription Anna Badalamenti
2022/09/01 - 2023/10/23 TERRA-mediated recruitment of SMARCAL1 in response to Telomeric Replication Stress João Pedro Pina Rebelo
2020/01/27 - 2021/09/30 TERRA Transcription Profiles in Human Cancer Cells Miguel Alves
Distinctions

Award

2006 Award of Merit
2005 Award of Merit