Identification
Personal identification
- Full name
- Bárbara Beatriz Pinheiro Ribeiro de Sousa
Citation names
- Sousa, Bárbara
Author identifiers
- Ciência ID
- 5816-C95D-1E6F
- ORCID iD
- 0000-0002-0990-022X
- Researcher Id
- K-8854-2014
- Scopus Author Id
- 12777326600
Email addresses
- bsousa@ipatimup.pt (Professional)
- bbeatrizs@gmail.com (Personal)
Addresses
- Rua Alfredo Allen 208, , 4200-135 , Porto, Porto, Portugal (Professional)
Websites
- https://www.i3s.up.pt/content/people?id=173&idg=17 (Professional)
Knowledge fields
- Medical and Health Sciences - Basic Medicine
Languages
Language | Speaking | Reading | Writing | Listening | Peer-review |
---|---|---|---|---|---|
Portuguese (Mother tongue) | |||||
English | Advanced (C1) | Advanced (C1) | Advanced (C1) | Advanced (C1) | Advanced (C1) |
Education
Degree | Classification | |
---|---|---|
2023/06/13 - 2023/06/29
Ongoing
|
Research Project Management, 3rd edition (Outros)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
|
|
2015/01/01 - 2018/12/31
Concluded
|
P-cadherin breast cancer stem cell marker: an antioxidant for metabolic defects caused by loss of matrix attachment (Pós-doutoramento)
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
|
|
2018/09/10 - 2018/09/21
Concluded
|
Laboratory Animal Science-FELASA C (Outros)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
|
|
2010/01/01 - 2014/12/15
Concluded
|
Pathology and Molecular Genetics (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
"Underlying the role of P-cadherin expression in breast cancer cell metabolism" (THESIS/DISSERTATION)
|
|
2001/09/06 - 2007/07/28
Concluded
|
Bioquímica (Licenciatura)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Immunohistochemical characterization of a series of invasive breast carcinomas using Tissue Microarrays" (THESIS/DISSERTATION)
|
15/20 |
Affiliation
Science
Category Host institution |
Employer | |
---|---|---|
2019/01/01 - Current | Contracted Researcher (Research) | Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal |
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal | ||
2015/01/01 - 2018/12/31 | Postdoc (Research) | Fundação para a Ciência e a Tecnologia, Portugal |
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal | ||
2016/06/01 - 2016/08/05 | Visiting Researcher (Research) | Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal |
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal | ||
2013/06/01 - 2013/07/31 | Visiting Researcher (Research) | Biopark by Sanofi, France |
Biopark by Sanofi, France | ||
2012/10/01 - 2012/12/17 | Visiting Researcher (Research) | PICR (Paterson Institute for Cancer Research, University of Manchester, Manchester), United Kingdom |
PICR (Paterson Institute for Cancer Research, University of Manchester, Manchester), United Kingdom | ||
2008/01/01 - 2009/12/31 | Contracted Researcher (Research) | Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal |
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal | ||
2007/07/01 - 2007/12/31 | Research Trainee (Research) | Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal |
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal |
Others
Category Host institution |
Employer | |
---|---|---|
2010/01/01 - 2014/12/31 | PhD student | Fundação para a Ciência e a Tecnologia, Portugal |
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal |
Projects
Grant
Designation | Funders | |
---|---|---|
2008/09/01 - 2010/12/31 | P-cadherin Expression: its effect in breast cancer metastasis and angiogenesis using in vivo animal models
SANO-AV
Research Fellow
|
Concluded
|
Contract
Designation | Funders | |
---|---|---|
2022/09/01 - 2023/08/08 | Development of a workflow to capture circulating tumour cell (CTC) clusters from patients with metastatic breast cancer
CANCER METASTASIS
Researcher
Liga Portuguesa Contra o Cancro, Portugal
|
Ongoing
|
Other
Designation | Funders | |
---|---|---|
2018/06/01 - 2021/07/31 | HOXB genes function in breast cancer
POCI-01-0145-FEDER-030562
Researcher
|
|
2017/01/01 - 2019/12/31 | Tackling CANcer STEM CELls: a challenge and an opportunity to advance in anti-cancer therapy
SAICTPAC/0022/2015 - POCI-01-0145-FEDER-016390
Researcher
|
|
2016/05/01 - 2019/04/30 | P-cadherin breast cancer stem cell marker: an anti-oxidant for metabolic defects caused by loss of matrix attachment
NORTE-01-0145-FEDER-00029
Researcher
|
Fundação para a Ciência e a Tecnologia
Ongoing
|
2014/06/01 - 2015/05/05 | Dasatinib as an option to treat P-cadherin-overexpressing poor prognosis breast cancer
Laço
Researcher
|
Concluded
|
2012/03/01 - 2015/02/28 | ADHESION, DIFFERENTIATION AND INVASION: DIFFERENT PROCESSES, COMMON CADHERIN PLAYERS
info:eu-repo/grantAgreement/FCT/SFRH/SFRH2%FBPD2%F757052%F2011/PT
Researcher
|
Fundação para a Ciência e a Tecnologia
Concluded
|
Outputs
Publications
Book chapter |
|
Conference poster |
|
Journal article |
|
Thesis / Dissertation |
|
Activities
Oral presentation
Presentation title | Event name Host (Event location) |
|
---|---|---|
2023/05/10 | P-cadherin-mediated cell-cell adhesion: its role on immune evasion in metastatic breast cancer (co-supervision) | IJUP Edition, Encontro de Investigação Jovem, Porto, Portugal
(Porto, Portugal)
|
2022/05/04 | P-cadherin as a phenotypic stability factor of the Hybrid Epithelial / Mesenchymal phenotype in Breast Cancer (co-supervision) | 15th Encontro de Investigação Jovem da Universidade do Porto
(Porto, Portugal)
|
2021/11/19 | P-cadherin as a phenotypic stability factor of the hybrid epithelial/mesenchymal phenotype in breast cancer (co-supervision) | 18th National Congress on Oncology, November
Sociedade Portuguesa de Oncologia
|
2019/11 | The anti-oxidant activity of P-cadherin promotes metastasis and therapy resistance in breast cancer | 8th i3S Annual Meeting
(Povoa de Varzim, Portugal)
|
2019/09 | P-cadherin induces anoikis resistance in breast cancer stem cells by rewiring the metabolic flux and activating of antioxidant systems | Oncometabolism: From Conceptual Knowledge to Clinical Applications
(Luso, Portugal)
|
2019/09 | The anti-oxidant activity of P-cadherin promotes metastasis and doxorubicin resistance in breast cancer | MAC’19- 6th Biannual Meeting on Mitochondria, Apoptosis & Cancer
(Praga, Czech Republic)
|
2019/01 | Circulating CSCs: how to survive upon metabolic alterations caused by matrix detachment | CANCEL STEM Consortium Meeting
UC-Biotech, Cantanhede, Portugal (Cantanhede, Portugal)
|
2018/10 | P-cadherin promotes anoikis resistance in breast cancer stem cells by stimulating the glycolytic behavior and lowering the oxidative stress | ISCaM 5th annual Meeting- Metabolic Adaptations and targets in Cancer, from International Society of Cancer Metabolism
(Bratislava, Slovakia)
|
2017/10 | P-cadherin expression: its role in the regulation of metabolic properties of breast cancer stem cells | 10th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies (SPCE-TC)
(Covilhã, Portugal)
|
2017/07 | P-cadherin expression: its role in the regulation of metabolic properties of breast cancer stem cells | FEBS ADVANCED LECTURE COURSE ON ONCOMETABOLISM: From Conceptual Knowledge to Clinical Applications
(Figueira da Foz, Portugal)
|
2016/11 | P-cadherin: an antioxidant for metabolic defects in breast cancer stem cells | 5th I3S Scientific Retreat, IBMC/INEB/IPATIMUP
(Povoa de Varzim, Portugal)
|
2015/10 | P-cadherin expression: its role in the regulation of metabolic properties of breast cancer stem cells | 7th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies (SPCE-TC)
(Lisboa, Portugal)
|
2014/05 | E-cadherin and P-cadherin: their crosstalk in breast cancer cells | 5th French Cell Adhesion Club Symposium
(Marselha, France)
|
Supervision
Thesis Title Role |
Degree Subject (Type) Institution / Organization |
|
---|---|---|
2023/01/01 - Current | P-cadherin-mediated cell-cell adhesion: its role in hybrid E/M phenotype and immune evasion in metastatic breast cancer (co-supervision)
Co-supervisor
|
Patologia e Genética Molecular (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
|
2020 - Current | The role of cell-cell adhesion in the survival of inflammatory breast cancer tumor emboli (co-supervision)
Co-supervisor
|
Patologia e Genética Molecular (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
|
2022/09/01 - 2023/09/30 | P-cadherin-mediated cell-cell adhesion: its role on immune evasion in metastatic breast cancer (co-supervision)
Co-supervisor
|
Mestrado em Bioquímica Clínica (Master)
Universidade de Aveiro, Portugal
|
2019/01/01 - 2019/06/30 | Evaluate the role of P-cadherin in the doxorubicin resistance of breast cancer stem cells
Co-supervisor
|
Bio-Medical Laboratory Technology bachelor (Degree)
Universiteit Gent, Belgium
|
2016/09 - 2017/09 | Targeting anoikis-resistant P-cadherin-enriched Breast Cancer Cells by in vitro Metabolic Reprograming
Co-supervisor
|
Bioquímica (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
|
Event participation
Activity description Type of event |
Event name Institution / Organization |
|
---|---|---|
2024/01/13 - Current | Ciencia et al- i3s Educational Program
Workshop
|
A Herança dos Maias
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
|
2023/10/01 - Current | Science Ambassador at i3S Educational Program: Circulating Tumor Cells and Breast Cancer
Exhibition
|
Ciencia et al
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
|
2023 - Current | Exposição coletiva de Fotografias “O CANCRO VISTO AO MICROSCÓPIO”
Exhibition
|
Exposição coletiva de Fotografias “O CANCRO VISTO AO MICROSCÓPIO”
Universidade de Aveiro, Portugal
|
2007 - Current | Participation in "Ciência Viva" exhibitions |
Ciência Viva, Portugal
|
2007 - Current | Dissemination of scientific research within an exhibition promoted by University of Porto targeting high school students: MOSTRA UP | MOSTRA UP
Universidade do Porto, Portugal
|
2014/11/14 - 2014/11/15 | Ipatimup - 2 Dias Abertos
Exhibition
|
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
|
2014/05/05 - 2014/05/12 | Exposição: Cancro, Ciência e Cidade: Os Passos da Ciência nos Paços do Concelho
Meeting
|
Exposição: Cancro, Ciência e Cidade: Os Passos da Ciência nos Paços do Concelho
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
Câmara Municipal do Porto, Portugal |
Jury of academic degree
Topic Role |
Candidate name (Type of degree) Institution / Organization |
|
---|---|---|
2023/11/30 | Tumor spheroids as 3D models to evaluate the efficacy of Azurin-expressing Mesenchymal Stromal Cells-secretome as a potential
anticancer therapy
(Thesis) Main arguer
|
Alexandra Amaral Barbosa (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
|
Course / Discipline taught
Academic session | Degree Subject (Type) | Institution / Organization | |
---|---|---|---|
2019 - 2020 | Participation in Invasion and Mestatasis module | Medicina (Mestrado integrado) | Universidade do Porto Faculdade de Medicina, Portugal |
2018 - 2019 | Participation in Invasion and Mestatasis module | Medicina (Mestrado integrado) | Universidade do Porto Faculdade de Medicina, Portugal |
2018 - 2019 | Participation in Oncometabolism module at BEB PhD programme | Biologia Experimental e Biomedicina (Doutoramento) | Universidade de Coimbra, Portugal |
2017 - 2018 | Participation in Oncobiology module in the lesson: Cancer stemness and differentiation | 20th GABBA Edition (Curso de doutoramento (conclusão de unidades curriculares)) | Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal |
2017 - 2018 | Participation in Invasion and Mestatasis module | Medicina (Mestrado integrado) | Universidade do Porto Faculdade de Medicina, Portugal |
Evaluation committee
Activity description Role |
Institution / Organization | Funding entity | |
---|---|---|---|
2018/02 - 2018/02 | Avaliador/Moderador de sessão de comunicações orais no 11º Encontro de Jovens Investigadores da U.PORTO
Evaluator
|
Distinctions
Award
2023 | Fulbright award: "Studying the impact of cell-cell adhesion on the metastatic process of Inflammatory Breast Cancer" (co-supervision)
Fulbright Portugal, Portugal
|
2022 | Bolsa de Investigação em Oncologia LPCC-NRS 2022 (co-supervision)
Liga Portuguesa Contra o Cancro, Portugal
|
2022 | Best Oral Communication at 15th Encontro de Investigação Jovem da Universidade do Porto 2022 (co-supervision) |
2021 | Best Oral Communication at 18th National Congress on Oncology 2021 (co-supervision) |
2012 | 3rd Award of Oncology poster session in 3rd I3S Scientific Retreat – IBMC/INEB/IPATIMUP, Póvoa de Varzim, Portugal. |
2012 | Best Poster Award - mTOR expression in basal-like breast cancer and the ability of Everolimus to inhibit the invasion cancer cell capacity (co-author) |