João Ricardo Araújo completed his PhD in Metabolism - Clinical and Experimentation on 12/18/2013 on the University of Porto, Faculty of Medicine, and the Bachelor in Nutrition Sciences on 09/19/2007 on the University of Porto, Faculty of Nutrition and Food Sciences. He is an Invited Assistant Professor at Universidade Nova de Lisboa, Faculty of Medical Sciences. He published 41 articles in specialized journals and wrote 3 book chapters. He supervised 2 master's thesis. He has received four awards. Participated as PhD Fellow in 1 project, as a Resarch Fellow in 2 projects, and as Postdoctoral Fellow in 1 project. He works in the areas of Biological Sciences with emphasis on Microbiology, Cell Biology, and Pharmacology. In his curriculum vitae the most frequent terms in the contextualization of his scientific production are: Folic Acid; Glucose; Gestational diabetes; Placenta; Nutrients; Fetal programming; Metabolism; Colorectal Cancer; Intestine; Microbiota; and Short-chain fatty acids.
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Personal identification

Full name
Joao Araujo
Date of birth
1984/02/27
Gender
Male

Citation names

  • Araujo, JR
  • Araujo J

Author identifiers

Ciência ID
5914-2B4F-6D01
Researcher Id
0000-0003-2491-1047

Email addresses

  • joaoricardo.araujo@nms.unl.pt (Professional)

Addresses

  • Nova Medical School, Faculdade de Ciências Médicas, Campo Mártires Pátria 130, Lisboa, 1169-056 , Lisboa, Lisboa, Portugal (Professional)

Knowledge fields

  • Natural sciences - Biological Sciences - Microbiology
  • Natural sciences - Biological Sciences - Cell Biology
  • Medical and Health Sciences - Basic Medicine - Pharmacology and pharmacy

Languages

Language Speaking Reading Writing Listening Peer-review
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Portuguese (Mother tongue)
French Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Degree Classification
2011
Concluded
 Metabolismo - Clínica e Experimentação (Doutoramento)
Major in Sem especialidade
Universidade do Porto Faculdade de Medicina, Portugal
"Impact of gestational diabetes mellitus in the maternal-to-fetal transport of nutrients and in placental development." (THESIS/DISSERTATION)
2002/09/19 - 2007/09/19
Concluded
 Ciências da Nutrição (Licenciatura)
Major in sem especialização
Universidade do Porto Faculdade de Ciências da Nutrição e Alimentação, Portugal
"Efeito de compostos presentes na dieta e de drogas de abuso na captação de glicose numa linha celular de trofobastos humanos (células BeWo) " (THESIS/DISSERTATION)
 15

Science

Category
Host institution 		Employer
2014/10/01 - 2019/10/15 Postdoc (Research) Institut Pasteur, France
Institut Pasteur Département Biologie cellulaire et Infection, France
2010/01/02 - 2013/12/18 Researcher (Research) Universidade do Porto Faculdade de Medicina, Portugal
Universidade do Porto Centro de Farmacologia e Biopatologia Química, Portugal
2007/09/20 - 2009/12/31 Researcher (Research) Universidade do Porto Faculdade de Medicina, Portugal
Universidade do Porto Centro de Farmacologia e Biopatologia Química, Portugal

Teaching in Higher Education

Category
Host institution 		Employer
2019/10/16 - Current Invited Assistant Professor (University Teacher) Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal

Others

Category
Host institution 		Employer
2002/09/19 - 2007/09/19 estudante de pré-graduação Universidade do Porto Faculdade de Ciências da Nutrição e Alimentação, Portugal
Universidade do Porto Faculdade de Ciências da Nutrição e Alimentação, Portugal

Grant

Designation Funders
2020/04/01 - 2020/06/30 Gut microbiota, "Spark and Flame" of COVID-19 disease
Research 4 COVID 19, FACC 20/7/107
Researcher
Universidade Nova de Lisboa, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded

Contract

Designation Funders
2021/03/01 - Current MONET: Unravelling Microbiota-gut-brain axis paintings in obesity-associated Neuroinflammation: the blackbErry signaTure study
PTDC/BAA-AGR/7419/2020
Co-PI
Universidade Nova de Lisboa, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2023/01/01 - 2026/12/31 Unravelling the potential of the wheat microbiome for the development of healthier, more sustainable and resilient wheat-derived food & feed products
Grant agreement ID: 101084344
Researcher
REQUIMTE LAQV Porto, Portugal

Universidade Nova de Lisboa, Portugal
European Commission Third Framework Programme
Ongoing
2013/09/01 - 2018/08/31 Targeting novel lipid pathways for treatment of cardiovascular disease
info:eu-repo/grantAgreement/EC/FP7/602222/EU
Post-doc Fellow
Institut Pasteur, France
 European Commission
Concluded
2010/01/01 - 2013/12/31 EFEITO DA DIABETES MELLITUS GESTACIONAL NO TRANSPORTE MATERNO-FETAL DE NUTRIENTES E NO DESENVOLVIMEN-TO PLACENTÁRIO
SFRH/BD/63086/2009
 Fundação para a Ciência e a Tecnologia
Concluded
2010/01/01 - 2012/12/31 Diabetes and placental function: the role of hyperglycaemia, oxidative stress and inflammation
info:eu-repo/grantAgreement/FCT/5876-PPCDTI/102239/PT
PhD Student Fellow
Universidade do Porto Centro de Farmacologia e Biopatologia Química, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2010/01/01 - 2012/12/31 A função placentária na diabetes: o papel da hiperglicemia, stresse oxidativo e inflamação
PTDC/SAU-OSM/102239/2008
Universidade do Porto Faculdade de Medicina, Portugal

Universidade do Porto Centro de Farmacologia e Biopatologia Química, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2007/07/01 - 2010/12/31 O transporte intestinal de componentes da dieta e protecção do cancro colo-rectal
PTDC/SAU-FCF/67805/2006
Universidade do Porto Faculdade de Medicina, Portugal

Universidade do Porto Centro de Farmacologia e Biopatologia Química, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2009/01/01 - 2009/12/31 Antioxidant and antiradical characterization of polyphenolic compounds; bioavailability, biological properties and cell signalling.
info:eu-repo/grantAgreement/FCT/5876-PPCDTI/65501/PT
Research Fellow
Universidade do Porto Centro de Farmacologia e Biopatologia Química, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2007/07/01 - 2008/12/31 Intestinal transport of diet components and protection against colorectal cancer
info:eu-repo/grantAgreement/FCT/5876-PPCDTI/67805/PT
Integration into Research Grant Fellow
Universidade do Porto Centro de Farmacologia e Biopatologia Química, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded

Publications

Book chapter
  1. Araujo, JR; Keating, Elisa; Martel, Fátima. "Polyunsaturated Fatty Acids and Gestational Diabetes". In Nutrition and Diet in Maternal Diabetes, edited by Patel VB, Preedy VR, Rajendram R., 451-463. New York: Springer International Publishing, 2017.
    Published • 10.1007/978-3-319-56440-1_34
  2. Keating, Elisa; Araujo, JR; Martel, Fátima. "Folic Acid Uptake and Its Regulation in the Placenta". In Human Placental Trophoblasts, edited by Duttaroy AK and Basak S, 173-190. United States: CRC Press, 2015.
    Published • 10.1201/b19151-16
  3. Goncalves, Pedro; Araujo, JR; Martel, Fátima. "Effect of polyunsaturated fatty acids and bile salts on butyrate uptake by intestinal epithelial cells". In CACO-2 Cells and Their Uses (Cell Biology Research Progress), edited by Megan A. Schultz, 89-99. New York, United States: Nova Science Publishers Inc, 2011.
    Published
Conference abstract
  1. Araujo, JR; Rodrigues, Catarina. "Interaction between food and intestinal microbiota - metabolic processes". Paper presented in XXI Portuguese Congress of Nutrition, Lisboa, 2022.
    Published
  2. Araujo, JR. "Folatos e envelhecimento: papel na função cognitiva, demência e depressão". Paper presented in XIII Portuguese Congress of Nutrition, Porto, 2014.
    Published
  3. Correia-Branco, Ana; Azevedo CF; Araujo, JR; Guimarães, João Tiago; Faria, Ana. "The polyphenol xantohumol inhibits the uptake of essential nutrients in human first trimester trophoblast and impacts placentation – a putative relationship with fetal programming of metabolic syndrome". Paper presented in 6th Symposium of Metabolism - markers in Metabolic Syndrome, Porto, 2014.
    Published
  4. Araujo, JR; Ramalho, Carla; Correia-Branco, Ana; Faria, Ana; Ferraz, Tiago.; Keating, Elisa; Martel, Fatima. "Type 1, but not gestational diabetes, is associated with an increase in placental oxidative stress and antioxidant capacity". Paper presented in 5th Symposium of Metabolism ¿metabolism throughout life, Porto, 2013.
    Published
  5. Correia-Branco, Ana; Azevedo, Cláudia; Araujo, JR; Guimarães, João Tiago; Elisa Keating; Martel, Fátima. "The polyphenol xantohumol reduces glucose uptake and affects viability, proliferation and migration of a first trimester trophoblast cell line (htr8/svneo cells)". Paper presented in 5th Symposium of Metabolism ¿metabolism throughout life, Porto, 2013.
    Published
  6. Azevedo CF; Correia-Branco, Ana; Araujo, JR; Guimarães, João Tiago; Elisa Keating; Martel, Fátima. "Kaempferol inhibits glucose uptake in a human breast cancer cell line: relationship to its anticarcinogenic effect". Paper presented in 5th Symposium of Metabolism ¿metabolism throughout life, Porto, 2013.
    Published
  7. Araujo, JR; Pereira, Ana Cláudia; Correia-Branco, Ana; Ferraz, Tiago; Keating, Elisa; Martel, Fátima. "Placental transport of glucose and amino acids is reduced by oxidative stress". Paper presented in 17th World Congress on Controversies in Obstetrics, Gynecology and Infertility (COGI), Lisboa, 2012.
    Published
  8. Araujo, JR; Correia-Branco, Ana; Ramalho, Carla; Martel, Fátima; Keating, Elisa. "Gestational diabetes reduces placental uptake of arachidonic and docosahexaenoic acids and interferes with trophoblast development". Paper presented in 22nd International Union of Biochemistry and Molecular Biology (IUBMB) and 37th Federation of European Biochemical Societies (FEBS) Congress, 2012, Sevilla, 2012.
    Published
  9. Araujo, JR; Pereira, Ana Cláudia; Correia-Branco, Ana; Keating, Elisa; Meireles, Manuela; Martel, Fatima. "Oxidative Stress decreases glucose uptake in a human placental cell line (BeWo cells)". Paper presented in 16th Biennial Meeting of the Society for Free Radical Research International (SFRRI), London, 2012.
    Published
  10. Araujo, JR; Correia-Branco, Ana; Ramalho, Carla; Keating, Elisa; Martel, Fatima. "Gestational diabetes mellitus reduces placental uptake of arachidonic long-chain polyunsaturated fatty acids and interferes with trophoblast development". Paper presented in Meeting of the International-Federation-of-Placenta-Associations (IFPA) 2012, Hiroshima, 2012.
  11. Goncalves, Pedro; Gregório, Inês; Araujo, JR; Martel, Fátima. "Studies on the anticarcinogenic effect of clotrimazole at the intestinal epithelial level and putative effect in energy substrate uptake". Paper presented in 24th Meeting of European Intestinal Transport Group, Oxford, 2012.
    Published
  12. Correia-Branco, Ana; Araujo, JR; Moreira, Liliana; Ramalho, Carla; Martel, Fátima; Elisa Keating. "Gestational diabetes, TNF-a and leptin affect folic acid uptake by the human syncytiotrophoblast: evidence for JAK/STAT signaling involvement". Paper presented in Meeting of the International-Federation-of-Placenta-Associations (IFPA) 2012, Hiroshima, 2012.
    Published
  13. Araujo, JR; Correia-Branco, Ana; Ramalho, Carla; Keating, Elisa. "Uptake of L-Methionine by BeWo cells: characterization and modulation by diabetes-associated conditions". Paper presented in 14th European Placenta Group Meeting, 2011.
    Published
  14. Elisa Keating; Araujo, JR; Correia-Branco, Ana; Ramalho, Carla; Martel, Fátima. "L-methionine transport in human cytotrophoblasts isolated from diabetic pregnancies". Paper presented in International Federation of Placenta Associations Meeting 2011, Geilo, 2011.
    Published
  15. Araujo, JR; Martel, Fátima. "Uptake of folic acid and methyltetrahydrofolic acid by rat and human blood-brain barrier endothelial cell lines". Paper presented in 16th World Congress on Basic and Clinical Pharmacology, Copenhagen, 2010.
    Published
  16. Goncalves, Pedro; Araujo, JR; Martel, Fátima. "Butyrate uptake and effect on proliferation, differentiation, viability and apoptosis of Caco-2 cells: influence of polyphenols". Paper presented in Experimental Biology 2010, Anaheim, 2010.
    Published
  17. Araujo, JR; Goncalves, Pedro; Martel, Fátima. "Uptake of folates by rat and human brain endothelial cell lines". Paper presented in Experimental Biology 2010, Anaheim, 2010.
    Published
  18. Almeida, Cidália; Araujo, JR; Monteiro, Rosário; Severo, Milton; Guimarães, João Tiago; Azevedo, Isabel; Martins, MJ. "Chronic ingestion of a hypersaline sodium-rich carbonated natural mineral water on an animal model of the metabolic syndrome - effects on blood pressure and plasma metabolic profile". Paper presented in 37th World Congress of the International Society of Medical Hydrology and Climatology: Medical Hydrology and Balneology: from molecules to society., Paris, 2010.
    Published
  19. Goncalves, Pedro; Araujo, JR; Martel, Fátima. "Comparison of butyrate uptake by two non-transformed intestinal epithelial cell lines". Paper presented in 23rd Meeting of European Intestinal Transport Group, Salerno, 2010.
    Published
  20. Tavares, Sandra; Pereira-Sousa, Joana; Pinho, Maria João; Araujo, JR; Martel, Fátima. "The effect of folate status on the uptake of physiologically relevant compounds by Caco-2 cells". Paper presented in 23rd Meeting of European Intestinal Transport Group, Salerno, 2010.
    Published
  21. Goncalves, Pedro; Araujo, JR; Pinho, Maria João; Martel, Fátima. "Influence of polyphenols in a colon tumoral cell line: effect on butyrate uptake and on proliferation, differentiation, viability and apoptosis". Paper presented in 16th World Congress of Basic and Clinical Pharmacology, WorldPharma2010, Copenhaga, 2010.
    Published
  22. Almeida, Cidália; Araujo, JR; Gonçalves, MC; Severo, Milton; Guimarães, João Tiago; Monteiro, Rosário; Martins, MJ. "Effects of mineral supplementation on a wide spectrum of Metabolic Syndrome features. Study performed on a fructose-fed animal model". Paper presented in II World Congress of Public Health Nutrition and I Latin American Congress of Community Nutrition, Porto, 2010.
    Published
  23. Araujo, JR; Goncalves, Pedro; Martel, Fatima. "Modulation of folic acid uptake into BeWo cells by cannabinoids". Paper presented in Experimental Biology 2009, New Orleans, 2009.
    Published
  24. Goncalves, Pedro; Araujo, JR; Martel, Fátima. "Modulation of butyrate uptake by Caco-2 cells". Paper presented in Experimental Biology 2009, 2009.
    Published
  25. Goncalves, Pedro; Araujo, JR; Martel, Fátima. "Effect of some natural mineral waters upon butyrate and glucose uptake by Caco-2 cells". Paper presented in 34th Federation of European Biochemical Societies (FEBS) Congress, 2009, Praga, 2009.
    Published
  26. Martel, Fátima; Araujo, JR; Goncalves, Pedro. "Modulation of folic acid in BeWo cells by cannabinoids". Paper presented in 34th Federation of European Biochemical Societies (FEBS) Congress, 2009, Praga, 2009.
  27. Ribeiro, Laura; Bastos, Pedro; Araujo, JR; Martins, MJ. "Modulation of COMT activity and expression by mineral nutrients". Paper presented in 34th Federation of European Biochemical Societies (FEBS) Congress, 2009, Praga, 2009.
    Published
  28. Goncalves, Pedro; Araujo, JR; Azevedo, Isabel; Martel, Fátima. "The effect of cannabinoids on the uptake of 2-deoxy-D-glucose by Caco-2 cells". Paper presented in Experimental Biology 2008, San Diego, 2008.
    Published
  29. Santos, Alejandro; Goncalves, Pedro; Araujo, JR; Martel, Fátima. "Effect of gadopentetate dimeglumine administration on intestinal permeability to glucose after traumatic brain injury.". Paper presented in Experimental Biology 2008, San Diego, 2008.
    Published
  30. Araujo, JR; Martel, Fatima. "Nutritional modulation of 3H-deoxy-glucose uptake by placental BeWo cells". Paper presented in International Proceedings of the Join Meeting of the Slovak Physiological Society and Physiological Society and Federation of European Physiological Societies, Bratislava, 2007.
    Published
  31. Araujo, JR; Goncalves, Pedro; Azevedo, Isabel; Martel, Fatima. "Nutritional modulation of glucose uptake by BeWo cells". Paper presented in 13th International Federation of Placenta Associations (IFPA)/2nd Placenta Association of the Americas (PAA) Conference “Placenta-Platform for Life”, Kingston, 2007.
    Published
  32. Araujo, JR; Martel, Fátima. "Nutritional modulation of 3H-Deoxy-Glucose uptake by placental BeWo cells". Paper presented in Join Meeting of the Slovak Physiological Society and Physiological Society and Federation of European Physiological Societies, Bratislava, 2007.
    Published
Journal article
  1. Barreiros-Mota, Inês; R. Araújo, João; Marques, Cláudia; Sousa, Laura; Morais, Juliana; Castela, Inês; Faria, Ana; et al. "Changes in Microbiota Profile in the Proximal Remnant Intestine in Infants Undergoing Surgery Requiring Enterostomy". Microorganisms 11 10 (2023): 2482. http://dx.doi.org/10.3390/microorganisms11102482.
    10.3390/microorganisms11102482
  2. Rodrigues, Tânia; Rodrigues Fialho, Sofia; Araújo, João Ricardo; Rocha, Rita; Moreira-Rosário, André. "Procedures in Fecal Microbiota Transplantation for Treating Irritable Bowel Syndrome: Systematic Review and Meta-Analysis". Journal of Clinical Medicine 12 5 (2023): 1725. http://dx.doi.org/10.3390/jcm12051725.
    10.3390/jcm12051725
  3. Castela, Inês; Morais, Juliana; Barreiros-Mota, Inês; Silvestre, Marta P.; Marques, Cláudia; Rodrigues, Catarina; Ismael, Shámila; et al. "Decreased adiponectin/leptin ratio relates to insulin resistance in adults with obesity". American Journal of Physiology-Endocrinology and Metabolism 324 2 (2023): E115-E119. http://dx.doi.org/10.1152/ajpendo.00273.2022.
    10.1152/ajpendo.00273.2022
  4. Ismael, Shámila; Rodrigues, Catarina; Santos, Gilberto Maia; Castela, Inês; Barreiros-Mota, Inês; Almeida, Maria João; Calhau, Conceição; Faria, Ana; Araújo, João Ricardo. "IPA and its precursors differently modulate the proliferation, differentiation, and integrity of intestinal epithelial cells". Nutrition Research and Practice 17 4 (2023): 616. http://dx.doi.org/10.4162/nrp.2023.17.4.616.
    10.4162/nrp.2023.17.4.616
  5. Araújo, João R.; Serafim, Thainá; Ismael, Shámila; Calhau, Conceição; Faria, Ana; Teixeira, Diana. "Intestinal Alkaline Phosphatase Activity and Efficiency Are Altered in Severe COVID-19 Patients". Gastro Hep Advances 2 7 (2023): 911-917. http://dx.doi.org/10.1016/j.gastha.2023.07.003.
    10.1016/j.gastha.2023.07.003
  6. Vonaesch, Pascale; Araújo, João R.; Gody, Jean-Chrysostome; Mbecko, Jean-Robert; Sanke, Hugues; Andrianonimiadana, Lova; Naharimanananirina, Tanteliniaina; et al. "Stunted children display ectopic small intestinal colonization by oral bacteria, which cause lipid malabsorption in experimental models". Proceedings of the National Academy of Sciences 119 41 (2022): http://dx.doi.org/10.1073/pnas.2209589119.
    10.1073/pnas.2209589119
  7. Castela, Inês; Rodrigues, Catarina; Ismael, Shámila; Barreiros-Mota, Inês; Morais, Juliana; Araújo, João R.; Marques, Cláudia; et al. "Intermittent energy restriction ameliorates adipose tissue-associated inflammation in adults with obesity: A randomised controlled trial". Clinical Nutrition 41 8 (2022): 1660-1666. http://dx.doi.org/10.1016/j.clnu.2022.06.021.
    Open access • Published • 10.1016/j.clnu.2022.06.021
  8. Santos, Gilberto Maia; Ismael, Shámila; Morais, Juliana; Araújo, João R.; Faria, Ana; Calhau, Conceição; Marques, Cláudia. "Intestinal Alkaline Phosphatase: A Review of This Enzyme Role in the Intestinal Barrier Function". Microorganisms 10 4 (2022): 746. http://dx.doi.org/10.3390/microorganisms10040746.
    Open access • Published • 10.3390/microorganisms10040746
  9. Moreira-Rosário, André; Marques, Cláudia; Pinheiro, Hélder; Araújo, João Ricardo; Ribeiro, Pedro; Rocha, Rita; Mota, Inês; et al. "Gut Microbiota Diversity and C-Reactive Protein Are Predictors of Disease Severity in COVID-19 Patients". Frontiers in Microbiology 12 (2021): http://dx.doi.org/10.3389/fmicb.2021.705020.
    Open access • Published • 10.3389/fmicb.2021.705020
  10. Morais, Juliana; Marques, Cláudia; Faria, Ana; Teixeira, Diana; Barreiros-Mota, Inês; Durão, Catarina; Araújo, João; et al. "Influence of Human Milk on Very Preterms’ Gut Microbiota and Alkaline Phosphatase Activity". Nutrients 13 5 (2021): 1564. http://dx.doi.org/10.3390/nu13051564.
    Open access • Published • 10.3390/nu13051564
  11. Ismael, Shámila; Silvestre, Marta P.; Vasques, Miguel; Araújo, João R.; Morais, Juliana; Duarte, Maria Inês; Pestana, Diogo; et al. "A Pilot Study on the Metabolic Impact of Mediterranean Diet in Type 2 Diabetes: Is Gut Microbiota the Key?". Nutrients 13 4 (2021): 1228. http://dx.doi.org/10.3390/nu13041228.
    Published • 10.3390/nu13041228
  12. Lema, Ingrid; Araújo, João Ricardo; Rolhion, Nathalie; Demignot, Sylvie. "Jejunum: The understudied meeting place of dietary lipids and the microbiota". Biochimie 178 (2020): 124-136. http://dx.doi.org/10.1016/j.biochi.2020.09.007.
    Published • 10.1016/j.biochi.2020.09.007
  13. Araújo, João R.; Tazi, Asmaa; Burlen-Defranoux, Odile; Vichier-Guerre, Sophie; Nigro, Giulia; Licandro, Hélène; Demignot, Sylvie; Sansonetti, Philippe J.. "Fermentation Products of Commensal Bacteria Alter Enterocyte Lipid Metabolism". Cell Host & Microbe (2020): http://dx.doi.org/10.1016/j.chom.2020.01.028.
    Published • 10.1016/j.chom.2020.01.028
  14. Tazi, Asmaa; Araujo, JR; Mulet, Céline; Arena, Ellen T.; Nigro, Giulia; Pédron, Thierry; Sansonetti, Philippe J.. "Disentangling Host-Microbiota Regulation of Lipid Secretion by Enterocytes: Insights from Commensals Lactobacillus paracasei and Escherichia coli". mBio 9 5 (2018): http://dx.doi.org/10.1128/mbio.01493-18.
    Published • 10.1128/mbio.01493-18
  15. Gonçalves, Pedro; Araujo, JR; Di Santo, James P. "A Cross-Talk Between Microbiota-Derived Short-Chain Fatty Acids and the Host Mucosal Immune System Regulates Intestinal Homeostasis and Inflammatory Bowel Disease". Inflammatory Bowel Diseases 24 3 (2018): 558-572. http://dx.doi.org/10.1093/ibd/izx029.
    Published • 10.1093/ibd/izx029
  16. Araujo, JR; Tomas, Julie; Brenner, Christiane; Sansonetti, Philippe J.. "Impact of high-fat diet on the intestinal microbiota and small intestinal physiology before and after the onset of obesity". Biochimie 141 (2017): 97-106. http://dx.doi.org/10.1016/j.biochi.2017.05.019.
    Published • 10.1016/j.biochi.2017.05.019
  17. Andrade, Nelson; Araujo, JR; Correia-Branco, Ana; Carletti, Jaqueline V.; Martel, Fátima. "Effect of dietary polyphenols on fructose uptake by human intestinal epithelial (Caco-2) cells". Journal of Functional Foods 36 (2017): 429-439. http://dx.doi.org/10.1016/j.jff.2017.07.032.
    Published • 10.1016/j.jff.2017.07.032
  18. Silva, Cláudia; Nunes, Catarina; Correia-Branco, Ana; Araujo, JR; Martel, Fátima. "Insulin Exhibits an Antiproliferative and Hypertrophic Effect in First Trimester Human Extravillous Trophoblasts". Reproductive Sciences 24 4 (2016): 582-594. http://dx.doi.org/10.1177/1933719116667220.
    Published • 10.1177/1933719116667220
  19. Guedes, Marta; Araujo, JR; Correia-Branco, Ana; Gregório, Inês; Martel, Fátima; Keating, Elisa. "Modulation of the uptake of critical nutrients by breast cancer cells by lactate: Impact on cell survival, proliferation and migration". Experimental Cell Research 341 2 (2016): 111-122. http://dx.doi.org/10.1016/j.yexcr.2016.01.008.
    Published • 10.1016/j.yexcr.2016.01.008
  20. Correia-Branco, Ana; Azevedo, Cláudia F.; Araujo, JR; Guimarães, João T.; Faria, Ana; Keating, Elisa; Martel, Fátima. "Xanthohumol impairs glucose uptake by a human first-trimester extravillous trophoblast cell line (HTR-8/SVneo cells) and impacts the process of placentation". Molecular Human Reproduction 21 10 (2015): 803-815. http://dx.doi.org/10.1093/molehr/gav043.
    Published • 10.1093/molehr/gav043
  21. Araujo, JR; Martel, Fátima; Borges, Nuno; Araújo, João Manuel; Keating, Elisa. "Folates and aging: Role in mild cognitive impairment, dementia and depression". Ageing Research Reviews 22 (2015): 9-19. http://dx.doi.org/10.1016/j.arr.2015.04.005.
    Published • 10.1016/j.arr.2015.04.005
  22. Gomes, Andreia; Correia, Gustavo; Coelho, Marisa; Araujo, JR; Pinho, Maria João; Teixeira, Ana Luisa; Medeiros, Rui; Ribeiro, Laura. "Dietary unsaturated fatty acids differently affect catecholamine handling by adrenal chromaffin cells". The Journal of Nutritional Biochemistry 26 5 (2015): 563-570. http://dx.doi.org/10.1016/j.jnutbio.2014.12.009.
    Published • 10.1016/j.jnutbio.2014.12.009
  23. Keating, Elisa; Correia-Branco, Ana; Araujo, JR; Meireles, Manuela; Fernandes, Rita; Guardão, Luísa; Guimarães, João T; Martel, Fátima; Calhau, Conceição. "Excess perigestational folic acid exposure induces metabolic dysfunction in post-natal life". Journal of Endocrinology 224 3 (2015): 245-259. http://dx.doi.org/10.1530/joe-14-0448.
    Published • 10.1530/joe-14-0448
  24. Azevedo, Cláudia; Correia-Branco, Ana; Araujo, JR; Guimarães, João T.; Keating, Elisa; Martel, Fátima. "The Chemopreventive Effect of the Dietary Compound Kaempferol on the MCF-7 Human Breast Cancer Cell Line Is Dependent on Inhibition of Glucose Cellular Uptake". Nutrition and Cancer 67 3 (2015): 504-513. http://dx.doi.org/10.1080/01635581.2015.1002625.
    Published • 10.1080/01635581.2015.1002625
  25. Araujo, JR; Keating, Elisa; Martel, Fátima. "Impact of Gestational Diabetes Mellitus in the Maternal-to-Fetal Transport of Nutrients". Current Diabetes Reports 15 2 (2015): http://dx.doi.org/10.1007/s11892-014-0569-y.
    Published • 10.1007/s11892-014-0569-y
  26. Gonçalves, Pedro; Araujo, JR; Martel, Fátima. "Antipsychotics-induced metabolic alterations: Focus on adipose tissue and molecular mechanisms". European Neuropsychopharmacology 25 1 (2015): 1-16. http://dx.doi.org/10.1016/j.euroneuro.2014.11.008.
    Published • 10.1016/j.euroneuro.2014.11.008
  27. Araujo, JR; Martel, Fátima; Keating, Elisa. "Exposure to non-nutritive sweeteners during pregnancy and lactation: Impact in programming of metabolic diseases in the progeny later in life". Reproductive Toxicology 49 (2014): 196-201. http://dx.doi.org/10.1016/j.reprotox.2014.09.007.
    Published • 10.1016/j.reprotox.2014.09.007
  28. Bastos, Pedro; Araujo, JR; Azevedo, Isabel; Martins, Maria João; Ribeiro, Laura. "Effect of a natural mineral-rich water on catechol-O-methyltransferase function". Magnesium Research 27 3 (2014): 131-141. http://dx.doi.org/10.1684/mrh.2014.0369.
    Published • 10.1684/mrh.2014.0369
  29. Pereira, Cidália Dionísio; Severo, Milton; Araujo, JR; Guimarães, João Tiago; Pestana, Diogo; Santos, Alejandro; Ferreira, Rita; et al. "Relevance of a Hypersaline Sodium-Rich Naturally Sparkling Mineral Water to the Protection against Metabolic Syndrome Induction in Fructose-Fed Sprague-Dawley Rats: A Biochemical, Metabolic, and Redox Approach". International Journal of Endocrinology 2014 (2014): 1-17. http://dx.doi.org/10.1155/2014/384583.
    Published • 10.1155/2014/384583
  30. Araujo, JR; Ramalho, C.; Correia-Branco, A.; Faria, Ana.; Ferraz, Tiago.; Keating, Elisa.; Martel, Fatima.. "A parallel increase in placental oxidative stress and antioxidant defenses occurs in pre-gestational type 1 but not gestational diabetes". Placenta 34 11 (2013): 1095-1098. http://dx.doi.org/10.1016/j.placenta.2013.09.001.
    Published • 10.1016/j.placenta.2013.09.001
  31. Araujo, JR; Pereira, Ana C.; Correia-Branco, Ana; Keating, Elisa; Martel, Fátima. "Oxidative stress induced by tert-butylhydroperoxide interferes with the placental transport of glucose: in vitro studies with BeWo cells". European Journal of Pharmacology 720 1-3 (2013): 218-226. http://dx.doi.org/10.1016/j.ejphar.2013.10.023.
    Published • 10.1016/j.ejphar.2013.10.023
  32. Araujo, JR; Correia-Branco, Ana; Ramalho, Carla; Keating, Elisa; Martel, Fátima. "Gestational diabetes mellitus decreases placental uptake of long-chain polyunsaturated fatty acids: involvement of long-chain acyl-CoA synthetase". The Journal of Nutritional Biochemistry 24 10 (2013): 1741-1750. http://dx.doi.org/10.1016/j.jnutbio.2013.03.003.
    Published • 10.1016/j.jnutbio.2013.03.003
  33. Araujo, JR; Correia-Branco, Ana; Pereira, Ana Cláudia; Pinho, Maria João; Keating, Elisa; Martel, Fátima. "Oxidative stress decreases uptake of neutral amino acids in a human placental cell line (BeWo cells)". Reproductive Toxicology 40 (2013): 76-81. http://dx.doi.org/10.1016/j.reprotox.2013.06.073.
    Published • 10.1016/j.reprotox.2013.06.073
  34. Meireles, Manuela; Martel, Fátima; Araujo, JR; Santos-Buelga, Celestino; Gonzalez-Manzano, Susana; Dueñas, Montserrat; de Freitas, Victor; et al. "Characterization and Modulation of Glucose Uptake in a Human Blood–Brain Barrier Model". The Journal of Membrane Biology 246 9 (2013): 669-677. http://dx.doi.org/10.1007/s00232-013-9583-2.
    Published • 10.1007/s00232-013-9583-2
  35. Araujo, JR; Correia-Branco, Ana; Ramalho, Carla; Gonçalves, Pedro; Pinho, Maria J.; Keating, Elisa; Martel, Fátima. "l-Methionine Placental Uptake: characterization and modulation in gestational diabetes mellitus.". Reproductive Sciences 20 12 (2013): 1492-1507. http://dx.doi.org/10.1177/1933719113488442.
    Published • 10.1177/1933719113488442
  36. Araujo, JR; Correia-Branco, Ana; Moreira, Liliana; Ramalho, Carla; Martel, Fátima; Keating, Elisa. "Folic acid uptake by the human syncytiotrophoblast is affected by gestational diabetes, hyperleptinemia, and TNF-a". Pediatric Research 73 1-4 (2013): 388-394. http://dx.doi.org/10.1038/pr.2013.14.
    Published • 10.1038/pr.2013.14
  37. Couto, Mafalda R.; Gonçalves, Pedro; Catarino, Telmo; Araujo, JR; Correia-Branco, Ana; Martel, Fátima. "The effect of oxidative stress upon the intestinal uptake of folic acid: in vitro studies with Caco-2 cells". Cell Biology and Toxicology 28 6 (2012): 369-381. http://dx.doi.org/10.1007/s10565-012-9228-8.
    Published • 10.1007/s10565-012-9228-8
  38. Araujo, JR; Martel, Fatima. "Sibutramine Effects on Central Mechanisms Regulating Energy Homeostasis". Current Neuropharmacology 10 1 (2012): 49-52. http://dx.doi.org/10.2174/157015912799362788.
    Published • 10.2174/157015912799362788
  39. Gonçalves, Pedro; Gregório, Inês; Araujo, JR; Martel, Fátima. "The effect of clotrimazole on energy substrate uptake and carcinogenesis in intestinal epithelial cells". Anti-Cancer Drugs 23 2 (2012): 220-229. http://dx.doi.org/10.1097/cad.0b013e32834d9ad2.
    Published • 10.1097/cad.0b013e32834d9ad2
  40. Gonçalves, Pedro; Araujo, JR; Martel, Fátima. "Characterization of Butyrate Uptake by Nontransformed Intestinal Epithelial Cell Lines". The Journal of Membrane Biology 240 1 (2011): 35-46. http://dx.doi.org/10.1007/s00232-011-9340-3.
    Published • 10.1007/s00232-011-9340-3
  41. Araujo, JR; Gonçalves, Pedro; Martel, Fátima. "Chemopreventive effect of dietary polyphenols in colorectal cancer cell lines". Nutrition Research 31 2 (2011): 77-87. http://dx.doi.org/10.1016/j.nutres.2011.01.006.
    Published • 10.1016/j.nutres.2011.01.006
  42. Goncalves, Pedro; Araujo, JR; Pinho, M. Joao; Martel, Fatima. "In Vitro Studies on the Inhibition of Colon Cancer by Butyrate and Polyphenolic Compounds". Nutrition and Cancer 63 2 (2011): 282-294. http://dx.doi.org/10.1080/01635581.2011.523166.
    Published • 10.1080/01635581.2011.523166
  43. Tavares, Sandra; Sousa, Joana; Gonçalves, Pedro; Araujo, JR; Martel, Fátima. "The effect of folate status on the uptake of physiologically relevant compounds by Caco-2 cells". European Journal of Pharmacology 640 1-3 (2010): 29-37. http://dx.doi.org/10.1016/j.ejphar.2010.04.056.
    Published • 10.1016/j.ejphar.2010.04.056
  44. Gonçalves, Pedro; Araujo, JR; Martel, Fátima. "Effect of Some Natural Mineral Waters in Nutrient Uptake by Caco-2 Cells". International Journal for Vitamin and Nutrition Research 80 2 (2010): 131-143. http://dx.doi.org/10.1024/0300-9831/a000013.
    Published • 10.1024/0300-9831/a000013
  45. Araújo, João R.; Gonçalves, Pedro; Martel, Fátima. "Characterization of uptake of folates by rat and human blood-brain barrier endothelial cells". BioFactors 36 3 (2010): 201-209. http://dx.doi.org/10.1002/biof.82.
    Published • 10.1002/biof.82
  46. Araujo, JR; Gonçalves, Pedro; Martel, Fátima. "Effect of Cannabinoids upon the Uptake of Folic Acid by BeWo Cells". Pharmacology 83 3 (2009): 170-176. http://dx.doi.org/10.1159/000192587.
    Published • 10.1159/000192587
  47. Gonçalves, Pedro; Araujo, JR; Martel, Fátima. "The effect of high glucose on SERT, the human plasmalemmal serotonin transporter". Nutritional Neuroscience 11 6 (2008): 244-250. http://dx.doi.org/10.1179/147683008x344156.
    Published • 10.1179/147683008x344156
  48. Gonçalves, Pedro; Araujo, JR; Pinho, Maria João; Martel, Fátima. "Modulation of butyrate transport in Caco-2 cells". Naunyn-Schmiedeberg's Archives of Pharmacology 379 4 (2008): 325-336. http://dx.doi.org/10.1007/s00210-008-0372-x.
    Published • 10.1007/s00210-008-0372-x
  49. Santos, Alejandro; Gonçalves, Pedro; Araujo, JR; Martel, Fátima. "Intestinal Permeability to Glucose after Experimental Traumatic Brain Injury: Effect of Gadopentetate Dimeglumine Administration". Basic & Clinical Pharmacology & Toxicology 103 3 (2008): 247-254. http://dx.doi.org/10.1111/j.1742-7843.2008.00272.x.
    Published • 10.1111/j.1742-7843.2008.00272.x
  50. Araujo, JR; Goncalves, Pedro; Martel, Fatima. "Modulation of Glucose Uptake in a Human Choriocarcinoma Cell Line (BeWo) by Dietary Bioactive Compounds and Drugs of Abuse". Journal of Biochemistry 144 2 (2008): 177-186. http://dx.doi.org/10.1093/jb/mvn054.
    Published • 10.1093/jb/mvn054
  51. Goncalves, Pedro; Araujo, JR; Azevedo, Isabel; Martel, Fatima. "Lack of a Significant Effect of Cannabinoids upon the Uptake of 2-Deoxy-D-Glucose by Caco-2 Cells". Pharmacology 82 1 (2008): 30-37. http://dx.doi.org/10.1159/000127408.
    Published • 10.1159/000127408

Oral presentation

Presentation title Event name
Host (Event location)
2023/05/03 Food and gut microbiota-derived metabolites: key actors in metabolic aging and disease Longevity Med Summit
(Cascais, Portugal)
2022/05/26 Interaction between food and intestinal microbiota – metabolic processes XXI Congresso Nutrição e Alimentação
Associação Portuguesa de Nutrição (Lisboa, Portugal)
2021/10/21 Interplay between intestinal microbiota and host metabolism IV International Conference NOVAhealth Chronic Disease and Infection com o tema Microbiota and Health
NOVAhealth Chronic Disease and Infection (Lisboa, Portugal)
2018/06/19 Deciphering the mechanisms by which E. coli and L. casei commensal strains modulate intestinal lipid metabolism Final Meeting of the Athero-Flux Consortium
Athero-Flux Consortium (Eretria, Greece)
2018/01/20 Deciphering the mechanisms by which E. coli and L. casei commensal strains modulate intestinal lipid metabolism Annual Meeting of the Athero-Flux Consortium
Athero-Flux Consortium (Rehovot, Israel)
2016/12/01 Modulation of intestinal lipid metabolism by commensal bacteria Cell Biology & Infection Day
Institut Pasteur Paris (Paris, France)
2016/11/07 Bacteria and Lipids Annual Meeting of the Athero-Flux Consortium
Athero-Flux Consortium (Asnière-sur-Oise, France)
2015/11/03 Microbiome and intestinal metabolism: fat(al) attraction Annual Meeting of the Athero-Flux Consortium
Athero-Flux Consortium (Athens, Greece)
2014/05/22 Folates and Ageing: role in cognitive decline, dementia and depression XIII Portuguese Congress of Nutrition
Associação Portuguesa de Nutricionistas (Porto, Portugal)
2011/05/12 Nutrition and Pregnancy: molecular studies concerning the maternal-to-fetal transport of glucose and folic acid X Portuguese Congress of Nutrition and II Ibero-American Congress of Nutrition
Associação Portuguesa de Nutricionistas (Lisboa, Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2022/10 - 2024/02/01 In vitro effect of intestinal microbiota-derived tryptophan metabolites on mechanisms of insulin resistance in adipocytes
Supervisor
 Microbiologia Médica (Master)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica António Xavier, Portugal
2021/09 - 2022/09 The efficacy of Fecal Microbiota Transplantation for the treatment of Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis
Supervisor
 Nutrição Humana e Metabolismo (Master)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2020/09 - 2021/11 Perfil do microbiota intestinal de recém-nascidos sujeitos a enterostomia
Supervisor of Laura da Conceição Costa Sousa
 Microbiologia Médica (Master)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2020/10 - 2021/07 A redução da atividade da fosfatase alcalina intestinal está associada à severidade da COVID-19
Supervisor
 Nutrição Humana e Metabolismo (Master)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2022/07/27 Portuguese shrimps: nutritional added value and contaminants evaluation. Risk-benefit
(Thesis) Main arguer
 Maria da Luz Galante Maia (PhD)
Universidade do Porto Departamento de Química e Bioquímica, Portugal

Conference scientific committee

Conference name Conference host
2014/02 - Current 7th Meeting of Young Researchers of University of Porto, Portugal. Porto, Portugal

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2022 - Current Nutrição, Microbiota Intestinal e Saúde Ciências da Nutrição (Licenciatura) Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2022 - Current Microbiota Intestinal. Implicações para a prática clínica Microbiota Intestinal. Implicações para a prática clínica (Pós-Graduação) Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2022 - Current Nutrição, Microbiota Intestinal e Saúde Medicina (Mestrado integrado) Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2021/10 - Current Tecnologia Alimentar e Novos Produtos Ciências da Nutrição (Licenciatura) Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2021/03 - Current Nutrição e Metabolismo Medicina (Mestrado integrado) Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2021 - Current Investigação Clínica em Nutrição Gestão da Investigação Clínica (Mestrado) Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2020/10 - Current Quimica dos Alimentos Ciências da Nutrição (Licenciatura) Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2020/03 - Current Metadologias de Investigação em Nutrição Nutrição Humana e Metabolismo (Mestrado integrado) Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2020/03 - Current O Papel do Microbioma na Saúde e na Doença Microbiologia Médica (Mestrado) Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2020/02 - Current Microbiologia Alimentar Ciências da Nutrição (Licenciatura) Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2020 - Current Metodologias de Investigação em Nutrição Ciências da Nutrição (Licenciatura) Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2020 - Current Nutrição e Metabolismo II Ciências da Nutrição (Licenciatura) Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2019/02 - Current Integração do Metabolismo e Nutrição Nutrição Humana e Metabolismo (Mestrado integrado) Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2019/01 - Current Fundamentos de Nutrição Molecular, Bioquimica e Fisiologia Nutrição Humana e Metabolismo (Mestrado integrado) Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2021 - 2021 Dietoterapia I Ciências da Nutrição (Licenciatura) Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2019/09 - 2020/01 Nutrição e Metabolismo Ciências da Nutrição (Licenciatura) Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2008 - 2013 Cultura de Células Animais Medicina (Doutoramento) Universidade do Porto Faculdade de Medicina, Portugal
2007/10 - 2012/07 Bioquímica I e II Medicina (Mestrado integrado) Universidade do Porto Faculdade de Medicina, Portugal

Evaluation committee

Activity description
Role 		Institution / Organization Funding entity
2015/06 - Current Evaluation of research projects with the reference to the Italian Call for Grant 2013 and 2019 (Italian Ministry of Health)
Evaluator
 Ministero della Salute, Italy Ministero della Salute
2018/06 - 2018/06 Evaluation of research projects with the reference to the “Fondo di Sviluppo e Coesione 2014-2020 - Regione Autonoma Della Sardegna 2017“ (Sardegna, Italy).
Evaluator
 Regione Autonoma della Sardegna, Italy Regione Autonoma della Sardegna

Journal scientific committee

Journal title (ISSN) Publisher
2019/07 - Current The Journal of Nutritional Biochemistry (0955-2863) Elsevier
2019/01 - Current Scientific Reports (2045-2322) Springer Science and Business Media LLC
2018/12 - Current Ageing Research Reviews (1568-1637) Elsevier
2018/09 - Current Journal of Clinical Medicine (2077-0383) MDPI AG
2018/03 - Current Frontiers in Genetics (1664-8021) Frontiers Media SA
2018/01 - Current Journal of the American College of Nutrition (1541-1087) Informa UK (Taylor & Francis)
2017/11 - Current Journal of Affective Disorders (0165-0327) Elsevier
2017/10 - Current Journal of Functional Foods (1756-4646) Elsevier
2017 - Current Acta Portuguesa de Nutrição (2183-5985) Portuguese Association of Nutritionists
2016/10 - Current European Journal of Clinical Nutrition (0954-3007) Springer Science and Business Media LLC
2016/08 - Current Nutrients (2072-6643) MDPI AG
2016/03 - Current Toxicology Letters (0378-4274) Elsevier
2015/03 - Current Clinical Nutrition (0261-5614) Elsevier
2014/11 - Current Reproductive Biology and Endocrinology (1477-7827) Springer (Biomed Central Ltd.)
2014/09 - Current Reproduction Fertility and Development (1031-3613) CSIRO Publishing
2014/08 - Current Cytokine (1096-0023) Elsevier
2014/03 - Current Nutrition Research (0271-5317) Elsevier
2013/10 - Current Journal of Cancer Therapy (2151-1942) "Scientific Research Publishing, Inc."
2013/08 - Current Reproductive Toxicology (0890-6238) Elsevier