Identification
Personal identification
- Full name
- Sara Inês Ascensão Tavares Canato
Citation names
- Sara Canato
Author identifiers
- Ciência ID
- 5B1E-A46C-091C
- ORCID iD
- 0000-0002-1102-0192
Email addresses
- sara.canato@research.fchampalimaud.org (Professional)
Telephones
- Telephone
-
- (+351) 210480141 (Professional)
Addresses
- Champalimaud Center for the Unknown, Avenida Brasília , 1400-038, Lisboa, Lisboa, Portugal (Professional)
Websites
- https://quantocancer.fchampalimaud.org/meet-our-team (Professional)
- https://fchampalimaud.org/research/groups/sanchez-danes (Professional)
Knowledge fields
- Natural sciences - Biological Sciences - Molecular Biology
- Natural sciences - Biological Sciences - Biochemistry
- Exact Sciences - Computer and Information Sciences - Bioinformatics
- Natural sciences - Biological Sciences - Biology
- Medical and Health Sciences - Clinical Medicine - Oncology
Languages
Language | Speaking | Reading | Writing | Listening | Peer-review |
---|---|---|---|---|---|
English | Advanced (C1) | Proficiency (C2) | Advanced (C1) | Advanced (C1) | Advanced (C1) |
Portuguese (Mother tongue) |
Education
Degree | Classification | |
---|---|---|
2014/01/05 - 2018/05/08
Concluded
|
Biology (Doutoramento)
Major in Systems Biology
Universidade de Lisboa Faculdade de Ciências, Portugal
"The endoplasmic reticulum quality control: dissecting protein networks in Cystic Fibrosis" (THESIS/DISSERTATION)
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2014/01/05 - 2014/06/30
Concluded
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Ph.D. Curricular Programme in Biology: Systems Biology (Doutoramento)
Major in Systems Biology
Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal
|
17.85 |
2010/09/16 - 2012/10/23
Concluded
|
Molecular Biology and Genetics (Mestrado)
Major in Ciências Biológicas
Universidade de Lisboa Faculdade de Ciências, Portugal
"Role of Ubiquitin Ligases in Pathophysiology of Cystic Fibrosis" (THESIS/DISSERTATION)
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16 |
2007/10/15 - 2010/08/20
Concluded
|
Biology (Licenciatura)
Major in Biological Sciences
Universidade de Évora, Portugal
"Diuron causes a decrease of antioxidant response in the Saccharomyces chevalieri UEME1" (THESIS/DISSERTATION)
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15 |
Affiliation
Science
Category Host institution |
Employer | |
---|---|---|
2021/06/01 - Current | Postdoc (Research) | Fundação Champalimaud, Portugal |
Fundação Champalimaud, Portugal | ||
2018/06/01 - 2021/05/30 | Postdoc (Research) | Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal |
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal (...) |
||
2014/11/05 - 2018/05/08 | Researcher (Research) | Fundação para a Ciência e a Tecnologia, Portugal |
Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal | ||
2012/12/01 - 2013/12/31 | Researcher (Research) | Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal |
Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal | ||
2011/06/01 - 2012/10/23 | Research Trainee (Research) | Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal |
Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal | ||
2010/01/01 - 2010/07/20 | Research Trainee (Research) | Universidade de Évora Departamento de Química, Portugal |
Universidade de Évora Departamento de Química, Portugal |
Projects
Grant
Designation | Funders | |
---|---|---|
2023/01/01 - Current | Uncovering the mechanisms of resistance to cancer formation in the developing brain
Post-doc
Fundação Champalimaud, Portugal
|
Fundação para a Ciência e a Tecnologia
Ongoing
|
2020/01/01 - 2021/05/25 | CANCEL STEM "Tackling CANcer STEM CELls: a challenge and an opportunity to advance in anticancer therapy"
POCI-01-0145- FEDER-016390
Post-doc Fellow
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
Instituto Gulbenkian de Ciência, Portugal |
Fundação para a Ciência e a Tecnologia European Regional Development Fund Concluded
|
2018/06/01 - 2019/12/31 | CoMEDy "A Computational Modelling platform for Epithelial Dynamics to explore the role of epithelial- mesenchymal transition
and stemness acquisition in cancer recurrence"
PTDC/BEX-BCB/0772/2014
Post-doc Fellow
Instituto Gulbenkian de Ciência, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
2018/06 - 2019/12 | CoMEDy "A Computational Modelling platform for Epithelial Dynamics to explore the role of epithelial- mesenchymal transition
and stemness acquisition in cancer recurrence"
PTDC/BEX-BCB/0772/2014
|
Fundação para a Ciência e a Tecnologia |
2016 - 2018/05/31 | MIMED - Mining the Molecular Metric Space for Drug Design
PTDC/EEI-ESS/4923/2014
PhD Student Fellow
|
Fundação para a Ciência e a Tecnologia
Concluded
|
2014/01/14 - 2018/05/31 | The endoplasmic reticulum quality control: dissecting protein networks in Cystic Fibrosis
SFRH/BD/5249/2014
PhD Student Fellow
Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal
|
Concluded
|
2012/12/01 - 2013/12/31 | Elucidating the role of novel CFTR interactors - new mechanisms in membrane protein trafficking
EXPL/BIM-MEC/1451/2013
Research Fellow
Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
Contract
Designation | Funders | |
---|---|---|
2021/06/01 - Current | QuantOCancer - "Leveraging the unique organismic approach to health and disease of the Champalimaud Foundation through the
inception of a quantitative biomedicine research programme focused on cancer"
H2020-WIDESPREAD-03-2017-ERAChairs–810653–
Post-doc
Fundação Champalimaud, Portugal
|
Ongoing
|
2014/04/01 - 2015/12/31 | Dissecting the endoplasmic reticulum quality control - differential protein interactions as new therapeutic targets in Cystic Fibrosis | Fundação para a Ciência e a Tecnologia |
2012/12/01 - 2013/12/31 | Characterization of ER-quality control for the F508del-CFTR protein: potential therapeutic targets for cystic fibrosis
PTDC/BIA-BCM/122299/2010
Research Fellow
Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
2011 - 2013 | Identification of Novel Targets Rescuing of F508del-CFTR Traffic: Mechanism of Action
7207534
Research Fellow
Cystic Fibrosis Foundation, United States
|
Cystic Fibrosis Foundation |
Outputs
Publications
Conference abstract |
|
Conference poster |
|
Journal article |
|
Report |
|
Thesis / Dissertation |
|
Other
Other output |
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Activities
Oral presentation
Presentation title | Event name Host (Event location) |
|
---|---|---|
2022/10/20 | Uncovering the mechanisms leading to Basal Cell Carcinoma initiation | Champalimaud Research Symposium: Tumour Microenvironment from cancer initiation to metastasis
Champalimaud Foundation (Lisbon, Portugal)
|
2019/02/19 | Computational modelling and experimental approaches identify novel partners of Src-induced EMT | Oncobiology Club
i3S (Porto, Portugal)
|
2019/02/05 | Computational modelling and experimental approaches identify novel partners of Src-induced EMT | Dev Meeting
i3S (Porto, Portugal)
|
2017/09/08 | Modulation of protein traffic networks to rescue F508del-CFTR from the endoplasmic reticulum | 17th FEBS Young Scientists' Forum
FEBS Young Scientists' Forum (Jerusalem, Israel)
|
2017/02/09 | Modulation of protein traffic networks to rescue F508del-CFTR from the endoplasmic reticulum | Chem&Biochem Postgraduate Students Meeting 2017
Chem&Biochem Postgraduate Students Meeting (Lisboa, Portugal)
|
2016/11/03 | CFTR traffic protein network in CF to modulate F508del-CFTR rescued | 3rd Proteostasis Action Meeting - Proteostasis and its Biological Implications
Proteostasis Action Meeting (Lisboa, Portugal)
|
2016/11 | BioSys-BioISI Graduate Student Council - 1st Summer Retreat BioSys-BioISI evaluation |
Biosytems and Integrative Science Institute (Lisboa, Portugal)
|
2016/07/23 | Identification of factors that regulate CFTR trafficking through the endoplasmic reticulum. | 1st Summer Retreat BioSys-BioISI- Assortativity and Cohesion: Tackling complex biological problems in Health and Disease through
System Biology
BioISI (Santa Cruz, Portugal)
|
2013/06/13 | Effect of the Burkholderia cenocepacia exoproteome on CFTR protein expression in human Cystic Fibrosis lug epithelial cell models | 36th European Cystic Fibrosis Conference
European Cystic Fibrosis (Lisboa, Portugal)
|
2013/03/20 | Potential role of expression of E3 Ubiquitin Ligases in regulating the inflammatory phenotype of Cystic Fibrosis | 10th European Cystic Fibrosis Society (ECFS) Basic Science Conference – New Frontiers in Basic Science of Cystic Fibrosis
European Cystic Fibrosis Society (Malaga, Spain)
|
Supervision
Thesis Title Role |
Degree Subject (Type) Institution / Organization |
|
---|---|---|
2022/09/01 - 2023/12/05 | Developing a 3D in vitro models of Basal Cell Carcinoma
Co-supervisor
|
NOVA Biomedical Research (Master)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
|
2020/09 - 2021/12/13 | Exploring the role of the actin MRTFA-SRF signalling pathway downstream of P-cadherin in basal-like breast cancer cells
Co-supervisor of Lídia Faria
|
MSc in oncobiology (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal |
2020/09/01 - 2021/05/29 | Investigate the TGF-ß-induced distinct phenotypes on the EMT continuum - Research fellowship Project LISBOA-01-0145-FEDER-016390
Co-supervisor of Inês Saraiva
|
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
|
2020/07/01 - 2020/08/31 | Investigate the TGF-ß-induced distinct phenotypes on the EMT continuum - Research fellowship Project LISBOA-01-0145-FEDER-016390
Co-supervisor of Jéssica Machado
|
|
2019/07/11 - 2019/09/12 | Project “CoMEDy – A Computational Modelling platform for Epithelial Dynamics to explore the role of epitelial-mesenchymal
transition and stemness acquisition in cancer recurrence.
The goal of this research project was to demonstrate that the synergistic effect between ECM stiffness and SRC, prevent
the acquisition of a full mesenchymal phenotype and is not depend of the epithelial cell type but are universal mechanisms
required for EMT.
Supervisor of Marta Mikonska
|
Animal Bioengineering - Erasmus traineeship (Other)
Szkola Glowna Gospodarstwa Wiejskiego, Poland
|
Event organisation
Event name Type of event (Role) |
Institution / Organization | |
---|---|---|
2016/02/01 - 2016/07/24 | Organization and coordenation of the Scientific Meeting - "Annual 1st Summer Retreat BioSys-BioISI- Assortativity and Cohesion:
Tackling complex biological problems in Health and Disease through System Biology". (2016/07/23 - 2016/07/23)
Conference (President of the Organising Committee)
|
Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal |
Event participation
Activity description Type of event |
Event name Institution / Organization |
|
---|---|---|
2021/06/14 - Current | Moderator of the CISS webinar session "A Response to the Coronavirus Pandemic: different flavors of T cell responses against
SARS-Cov-2" presented by Carolina Gorgulho, Maeurer Lab
Meeting
|
CISS Webinar
Fundação Champalimaud, Portugal
|
2024/02/06 - 2024/02/06 | Career Development - Workshop Effective Networking for Career Progression
Workshop
|
Postdoc day
Fundação Champalimaud, Portugal
|
2022/11/18 - 2022/11/18 | Workshop conflict management and effective communication in the Lab. COLife Postdoc day
Workshop
|
COLife Postdoc day
Fundação Champalimaud, Portugal
Instituto Gulbenkian de Ciência, Portugal Universidade de Lisboa Instituto de Medicina Molecular, Portugal |
2022/10/20 - 2022/10/21 | Champalimaud Research Symposium: Tumour Microenvironment from cancer initiation to metastasis. Uncovering the mechanisms leading
to Basal Cell Carcinoma initiation. Sara Canato*, Rahul Sarate, Raquel Soares, Yura Song, Mélanie Liagre, Sofia Marques,
Cédric Blanpain* & Adriana Sánchez-Danés. (Postdoc research). *Presentation
Symposium
|
Champalimaud Research Symposium: Tumour Microenvironment from cancer initiation to metastasis
Fundação Champalimaud, Portugal
|
2022 - 2022 | CR Research night
Other
|
CR Research night
Fundação Champalimaud, Portugal
|
2020/12/18 - 2020/12/18 | Workshop of the Portuguese Network on Extracellular Vesicles
Workshop
|
Workshop of the Portuguese Network on Extracellular Vesicles, online event
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
|
2019/11/28 - 2019/11/29 | Poster presentation of the Postdoctoral research
Meeting
|
i3S Annual Meeting. Póvoa de Varzim, Portugal.
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
|
2019/01/16 - 2019/01/16 | CANCEL STEM Consortium Meeting
Meeting
|
CANCEL STEM Consortium Meeting
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Biocant Associação de Transferência de Tecnologia, Portugal |
2018/11/29 - 2018/11/30 | Poster presentation of the Postdoctoral research
Meeting
|
i3S Annual Meeting 2018. Póvoa de Varzim, Portugal.
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
|
2017/10/06 - 2017/10/07 | Poster presentation of the Ph.D. work
Chair session IV -Bioinformatic approaches for Biomedicine
Meeting
|
2nd Summer Retreat BioSys-BioISI - Systems approach for biological problems. Beja, Portugal.
Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal
|
2017/09/10 - 2017/09/14 | Poster presentaion of the Ph.D. work
Conference
|
42nd FEBS Congress – From molecules to cell and back. Jerusalem, Israel.
Federation of European Biochemical Societies, United Kingdom
|
2017/09/10 - 2017/09/14 | Oral and poster presentation of the Ph.D. work
Conference
|
17th FEBS Young Scientists' Forum. Jerusalem, Israel.
Federation of European Biochemical Societies, United Kingdom
|
2017/02/09 - 2017/02/09 | Oral presentation of the Ph.D. work
Meeting
|
Chem&Biochem Postgraduate Students Meeting. Lisbon, Portugal
Universidade de Lisboa Faculdade de Ciências, Portugal
|
2017 - 2017 | Experimental demonstrations of the research work in Cystic Fibrosis disease for schools and general people
Other
|
Science Faculty of Lisbon University open day
Universidade de Lisboa Faculdade de Ciências, Portugal
|
2016/11/02 - 2016/11/05 | Oral presentation of the Ph.D. work
Meeting
|
3rd Proteostasis Action Meeting - Proteostasis and its Biological Implications
Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas, Portugal
|
2016/07/23 - 2016/07/24 | Oral presentation and Poster of the PhD work
Meeting
|
1st Summer Retreat BioSys-BioISI- Assortativity and Cohesion: Tackling complex biological problems in Health and Disease through
System Biology. Santa Cruz, Portugal.
Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal
|
2016/07/04 - 2016/07/06 | Poster presentation of the Ph.D. work
Meeting
|
Ciência 2016 – Science and Technology in Portugal Meeting. Lisbon, Portugal.
Presidência da República Portuguesa, Portugal
|
2016/04/26 - 2016/04/27 | Workshop Effective Scientific Writing
Workshop
|
Workshop Effective Scientific Writing
Universidade de Lisboa Faculdade de Ciências, Portugal
|
2016/03/30 - 2016/04/02 | Poster presentation of the PhD work
Conference
|
13th European Cystic Fibrosis Society (ECFS) Basic Science Conference – New Frontiers in Basic Science of Cystic Fibrosis.
Pisa, Italy.
European Cystic Fibrosis Society, Denmark
|
2016 - 2016 | Experimental demonstrations of the research work in Cystic Fibrosis disease for the general people
Other
|
European researcher’s night. Lisbon
Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal
|
2016 - 2016 | European researcher’s night
Other
|
European researcher’s night
Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal
|
2015 - 2015 | Experimental demonstrations of the research work in Cystic Fibrosis disease for the general people
Other
|
European researcher’s night. Lisbon
Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal
|
2015 - 2015 | European researcher’s night
Other
|
European researcher’s night
Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal
|
2014/03/26 - 2014/03/29 | Poster presentation of the Research Assistant in Biochemistry
Conference
|
11th European Cystic Fibrosis Society (ECFS) Basic Science Conference – New Frontiers in Basic Science of Cystic Fibrosis.
Malta.
European Cystic Fibrosis Society, Denmark
|
2013/07/18 - 2013/07/18 | Poster presentation of the M.Sc. work
Meeting
|
Molecular Biology in Portugal and EMBL and EMBL Alumni Meeting. Lisbon, Portugal.
European Molecular Biology Laboratory, France
|
2013/07/15 - 2013/07/16 | Poster presentation of the M.Sc. work
Meeting
|
EMBO Young Scientists’ Forum. Lisbon, Portugal.
European Molecular Biology Organization -EMBO, Germany
|
2013/06/12 - 2013/06/15 | Oral presentation M.Sc. work
Conference
|
36th European Cystic Fibrosis Conference. Lisbon, Portugal
European Cystic Fibrosis Society, Denmark
|
2013/03/20 - 2013/03/23 | Oral and Poster presentation of the M.Sc. work
Conference
|
10th European Cystic Fibrosis Society (ECFS) Basic Science Conference – New Frontiers in Basic Science of Cystic Fibrosis.
Malaga, Spain.
European Cystic Fibrosis Society, Denmark
|
2013 - 2013 | Learn electron microscopy applications
Workshop
|
Application of Electron Microscopy to Biomedicine
Instituto Superior de Ciências da Saúde Egas Moniz, Portugal
|
2011/09/21 - 2011/09/25 | Bioinformatics and systems modelling
Workshop
|
Bioinformatics and systems modelling
Universidade de Lisboa Faculdade de Ciências, Portugal
|
2011 - 2011 | Learn bioinformatics approaches and computational modelling
Workshop
|
Workshop Bioinformatics and System Modelling
Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal
|
2011 - 2011 | Learn theoretical and piratical techniques of epithelial cell differentiation
Workshop
|
Workshop Epithelial cell differentiation, cilia & physiology
Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal
|
2011 - 2011 | Learn PCR techniques
Workshop
|
PCR practice
We Value, Portugal
|
2009 - 2009 | Learn experimental techniques of microbiology
Workshop
|
Techniques of Microbiology and Laboratorial Chemistry
ECC laboratory, Lda, Portugal
|
Jury of academic degree
Topic Role |
Candidate name (Type of degree) Institution / Organization |
|
---|---|---|
2022/11/15 | Investigating the functional relevance of FOXM1 isoforms and truncated forms in breast cancer cell tumorigenesis
(Thesis) Arguer
|
Komal Khalil (Master)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal |
Association member
Society Organization name | Role | |
---|---|---|
2016/03/11 - Current | Sociedade Portuguesa de Bioquímica |
Course / Discipline taught
Academic session | Degree Subject (Type) | Institution / Organization | |
---|---|---|---|
2022/10/03 - 2022/10/07 | Single-Cell RNA-seq analysis using R | European Bioinformatics Institute, United Kingdom | |
2021/01/07 - 2021/03/10 | 104th training of trainers, accredited by Instituto do Emprego e Formação Professional (IEFP) | Professional Certification of Trainers’ Pedagogical Competences - CCP (Outros) | Instituto CRIAP, Portugal |
2020/09/07 - 2020/10/08 | LABORATORY ANIMAL SCIENCE COURSE FUNCTIONS [A], [B] AND [D] ACCORDING DIRECTIVE 2010/63/EU, Species specific MOUSE; RAT, ZEBRAFISH and FISH FELASA accredited course | Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal |
Evaluation committee
Activity description Role |
Institution / Organization | Funding entity | |
---|---|---|---|
2017/10/07 - 2017/10/07 | Chair of session IV - Bioinformatic approaches for Biomedicine in the scientific meeting "2nd Summer Retreat BioSys-BioISI
- Systems approach for biological problems".
Evaluator
|
Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal |
Journal scientific committee
Journal title (ISSN) | Publisher | |
---|---|---|
2019/06/01 - Current | JoLS, Journal of Life Sciences (2688-1020) |
Mentoring / Tutoring
Topic | Student name | |
---|---|---|
2021/09/01 - 2022/08/31 | Master student Lab teaching and support | Andrea Castaneda, Biopharmaceutical Sciences, FFUL |
2016/09/12 - 2017/09/01 | Master student Lab teaching and support | Sofias Ramalho; Department of Biochemistry, FCUL. |
2016/09/12 - 2017/09/01 | Master student Lab teaching and support | Iris Lameiro; Department of Biochemistry, FCUL. |
2015/01/03 - 2016/12/31 | Ph.D. student lab teaching and support | João Santos; 2nd edition BioSys PhD program, FCUL |
2013/01/01 - 2014/12/31 | Master student Lab teaching and support | Onofrio Laselva; Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari |
2012/06/01 - 2013/07/12 | Undergraduated student Lab teaching | Margarida Quaresma, Department of Biochemistry, FCUL. |
Distinctions
Award
2021 | Fellowship in Oncology LPCC-NRN-2021 - Liga Portuguesa Contra Cancro
Liga Portuguesa Contra o Cancro, Portugal
|
2017 | Young Scientists Fellowship
Federation of European Biochemical Societies, United Kingdom
|
Other distinction
2018 | Postdoctoral Fellowship
Fundação para a Ciência e a Tecnologia, Portugal
|
2016 | Travel Grant
European Cystic Fibrosis Society, Denmark
|
2014 | Travel Grant
European Cystic Fibrosis Society, Denmark
|
2014 | PhD Student Fellowship
Fundação para a Ciência e a Tecnologia, Portugal
|
2014 | Research Fellowship
Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal
|
2013 | Travel Grant
European Cystic Fibrosis Society, Denmark
|