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Teresa Sousa (PharmD, PhD) is an experienced pharmacologist, having worked for more than 18 years in basic and clinical research projects, as well as a pharmacology teacher, following her PhD in Pharmacology (2006,U.Porto), developed at the Institute of Pharmacology and Therapeutics, Faculty of Medicine, U.Porto (FMUP) and at the Toxicology Lab, Faculty of Pharmacy, U.Porto (FFUP). Currently, she is an Assistant Investigator (Research Career, University of Porto) and Lecturer at the Department of Biomedicine – Unit of Pharmacology and Therapeutics, FMUP. She is the Module Director of “Pharmacology of Synaptic Transmission” (Doctoral Programme in Neurosciences) and “Neuronal Excitability and Neurotransmission” (Master in Neurobiology), also participating in teaching activities in other Doctoral Programmes and Masters at FMUP, related to Pharmacology and Metabolism. She is also an Effective Member of the Portuguese Societies of Pharmacology and Neurosciences. She began her career by studying the interrelationship between the purinergic system, the renin-angiotensin-aldosterone system (RAAS), the sympathetic nervous system and oxidative stress responses in animal models of arterial hypertension. After her PhD, she had the opportunity to collaborate in clinical studies in the fields of heart failure and childhood obesity. Additionally, she has also collaborated in experimental studies of inflammatory bowel disease. In 2009, while studying the protective effects of low-dose aspirin in cardiovascular diseases, she became deeply interested in the field of resolution of inflammation/resolution pharmacology, still poorly explored. Since then, she has been intensively dedicated to the study of INFLAMMATION AND RESOLUTION PHARMACOLOGY in human diseases (chonic and acute heart failure, cardiogenic shock, septic shock and COVID-19) and in animal models (animal model of arterial hypertension; animal model of neuropathic pain). These projects were funded by FEDER/POCI and FCT in competitive calls and received awards/prizes by the European Society of Hypertension (ESH) (2013), Grünenthal Foundation (2018), European Society for Clinical Investigation (2020) and YES Meeting (2019, 2023). Recently, she was Editor of the Research Topic: “Specialized proresolving mediators: benefits within and beyond inflammation resolution in cardiometabolic, neurological and psychiatric disorders”, published in Frontiers of Physiology, 2023, and was also invited to participate in a COST Action related to Resolution Biology & Pharmacology.
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Identification

Personal identification

Full name
Teresa Sousa

Citation names

  • Sousa, Teresa

Author identifiers

Ciência ID
5C11-68F9-76AD
ORCID iD
0000-0001-7230-5020
Scopus Author Id
6603380101

Knowledge fields

  • Medical and Health Sciences - Basic Medicine - Pharmacology and pharmacy
  • Medical and Health Sciences - Basic Medicine - Neurosciences
  • Medical and Health Sciences - Clinical Medicine - Cardiac and Cardiovascular Systems
  • Medical and Health Sciences - Clinical Medicine - Paediatrics

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English
French
Education
Degree Classification
2006/05/05
Concluded
 Farmacologia (Doutoramento)
Major in Sem especialidade
Universidade do Porto Faculdade de Farmácia, Portugal
"A Hipertensão Causada por um Bloqueador dos Receptores da Adenosina. Papel do Stress Oxidativo/ Hypertension induced by an antagonist of adenosine receptors. Role of oxidative stress." (THESIS/DISSERTATION)
 Approved by unanimity
1999/07/13
Concluded
 Ciências Farmacêuticas (Licenciatura)
Major in Não Aplicável
Universidade do Porto Faculdade de Farmácia, Portugal
Affiliation

Science

Category
Host institution 		Employer
2020/09/01 - Current Auxiliary Researcher (Research) Universidade do Porto Faculdade de Medicina, Portugal
Universidade do Porto Faculdade de Medicina, Portugal
2014 - Current Researcher (Research) Universidade do Porto Centro de Investigação Farmacológica e Inovação Medicamentosa, Portugal
Universidade do Porto Centro de Investigação Farmacológica e Inovação Medicamentosa, Portugal
2019/01/01 - 2020/08/31 Contracted Researcher (Research) Universidade do Porto Faculdade de Medicina, Portugal
Universidade do Porto Faculdade de Medicina, Portugal
2015/10/01 - 2018/12/31 Postdoc (Research) Fundação para a Ciência e a Tecnologia, Portugal
Universidade do Porto Faculdade de Medicina, Portugal
2009/07/01 - 2014/06/30 Contracted Researcher (Research) Universidade do Porto Faculdade de Medicina, Portugal
Universidade do Porto Faculdade de Medicina, Portugal
2006/06/01 - 2009/06/30 Postdoc (Research) Fundação para a Ciência e a Tecnologia, Portugal
Universidade do Porto Faculdade de Medicina, Portugal
2002/01/01 - 2006/05/05 Researcher (Research) Fundação para a Ciência e a Tecnologia, Portugal
Universidade do Porto Faculdade de Medicina, Portugal
(...)
2000/01/01 - 2001/12/31 Research Trainee (Research) Universidade do Porto Faculdade de Medicina, Portugal
Universidade do Porto Faculdade de Medicina, Portugal
1999/01 - 1999/12 Research Trainee (Research) Universidade do Porto Faculdade de Medicina, Portugal
Universidade do Porto Faculdade de Medicina, Portugal

Teaching in Higher Education

Category
Host institution 		Employer
2020/02/10 - Current Lecturer (University Teacher) Universidade do Porto Faculdade de Medicina, Portugal
Universidade do Porto Faculdade de Medicina, Portugal
2017/09/01 - 2020/02/09 Invited Assistant Professor (University Teacher) Universidade do Porto Faculdade de Medicina, Portugal
2015/09/30 - 2017/08/31 Invited Assistant Professor (University Teacher) Universidade do Porto Faculdade de Medicina, Portugal
2008/10/27 - 2015/09/13 Tutor (University Teacher) Universidade do Porto Faculdade de Medicina, Portugal
Universidade do Porto Faculdade de Medicina, Portugal
2006/10/17 - 2012/10/06 Invited Assistant (University Teacher) Universidade do Porto Faculdade de Farmácia, Portugal
2002 - 2004 Invited Assistant (University Teacher) Instituto Universitário de Ciências da Saúde, Portugal
Instituto Universitário de Ciências da Saúde, Portugal
Projects

Grant

Designation Funders
2015 - 2018 Resolving inflammation in heart failure: lipoxins as new therapeutic targets.
SFRH/BPD/112005/2015
Post-doc Fellow
Universidade do Porto Faculdade de Medicina, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2006 - 2009 Role of angiotensin II-induced oxidative stress in the pathogenesis of arterial hypertension.
SFRH/BPD/21863/2005
Post-doc Fellow
Universidade do Porto Faculdade de Medicina, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2002 - 2006 Hypertension induced by an antagonist of adenosine receptors. Role of oxidative stress.
SFRH/BD/7055/2001
PhD Student Fellow
Universidade do Porto Faculdade de Farmácia, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded

Contract

Designation Funders
2018/07/15 - 2022/07/14 Resolution of inflammation: a missing key to improve acute heart failure treatment and prognosis?
PTDC/MEC-CAR/32188/2017
POCI-01-0145-FEDER- 032188
Principal investigator
Universidade do Porto Faculdade de Medicina, Portugal
 Fundação para a Ciência e a Tecnologia

European Regional Development Fund
Concluded
2020/07/09 - 2021/07/08 Unresolved inflammation and endothelitis in severe COVID-19 patients: identification of risk stratification biomarkers and therapeutic targets
613690173
Researcher
Universidade do Porto Faculdade de Medicina, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2014/04 - 2015/08 RES4MED: learning medicine through research
Provided by PTCRIS: 134327
EXPL/IVC-PEC/1302/2013
Researcher
Universidade do Porto Faculdade de Medicina, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2013/05 - 2015/04 Childhood obesity-related inflammation and vascular injury - Impact on the kidney
Provided by PTCRIS: 124426
PTDC/DTP-PIC/0239/2012
Researcher
Universidade do Porto Instituto de Saúde Pública, Portugal
 Fundação para a Ciência e a Tecnologia

European Regional Development Fund
Concluded
2011/04 - 2014/09 Interaction of aspirin with antihypertensive drugs - impact on renal oxidative stress, inflammation, local renin-angiotensin system activation and blood pressure control
Provided by PTCRIS: 114166
PTDC/SAU-TOX/114166/2009
Principal investigator
Universidade do Porto Faculdade de Medicina, Portugal
 Fundação para a Ciência e a Tecnologia

European Regional Development Fund
Concluded
2009 - 2010 Evaluation of intrarenal renin-angiotensin system activation and oxidative stress in chronic heart failure.
PP-IJUP2009-119
Principal investigator
Universidade do Porto Faculdade de Medicina, Portugal
 Universidade do Porto

Banco Santander Totta
Concluded
2000/01/01 - 2001/12/31 Crosstalk between bradykinin and an unknown agent (angiotensin II?) on the endothelial control of heart function and arterial vasomotricity
Praxis/C/SAU/14294/1998
Research Fellow
Universidade do Porto Faculdade de Medicina, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded

Other

Designation Funders
2019 - 2020 Redox dysfunction as a therapeutic target in neuropathic pain: specific inhibition of NADPH oxidase isoform 2 (NOX2)
s/ref
Researcher
Universidade do Porto Faculdade de Medicina, Portugal

Universidade do Porto Centro de Investigação Farmacológica e Inovação Medicamentosa, Portugal
Fundação Grünenthal
Concluded
2018 - 2019 Oxidative dysfunction and neuroinflammation as targets in neuropathic pain: mediators of pro-resolving inflammation.
s/ref
Researcher
Universidade do Porto Faculdade de Medicina, Portugal
 Fundação Grünenthal
Concluded
2002 - 2003 Role of renin-angiotensin system activation in vascular redox dysfunction.
s/ref
Researcher
Universidade do Porto Faculdade de Medicina, Portugal
 Fundação Calouste Gulbenkian
Concluded
Outputs

Publications

Book chapter
  1. Sousa, Teresa; Reina-Couto, Marta; Gomes, Pedro. "Role of Oxidative Stress in the Pathophysiology of Arterial Hypertension and Heart Failure". In Oxidative Stress in Heart Diseases, edited by Chakraborti S;; Dhalla NS;; Ganguly N;; Dikshit M;, 509-537. Springer Singapore, 2019.
    Published • 10.1007/978-981-13-8273-4_23
  2. Morato, Manuela; Reina-Couto, Marta; Pinho, Dora; Albino-Teixeira, António; Sousa, Teresa. "Regulation of the Renin-Angiotensin-Aldosterone System by Reactive Oxygen Species". In Renin-Angiotensin System - Past, Present and Future, edited by Anna Tolekova;, 119-157. InTech, 2017.
    Published • 10.5772/67016
  3. Sousa, Teresa; Afonso, Joana; Carvalho, Félix; Albino-Teixeira, António. "Lipid Peroxidation and Antioxidants in Arterial Hypertension". In Lipid Peroxidation, edited by Dr. Angel Catala, 345-392. InTech, 2012.
    Published • 10.5772/50346
Conference abstract
  1. Reina-Couto, M.; Pereira-Terra, Patricia; Silva-Pereira, Carolina; Quelhas-Santos Janete; Martins, Sandra; Teixeira-Santos, Luísa; Pinho, Dora; et al. Corresponding author: Reina-Couto, M.. "Lipoxins receptor is associated with prognosis and endothelitis in icu patients with acute heart failure but not in those with cardiogenic shock. Intensive Care Medicine Experimental 2023, 11 (Suppl 1): 001280". Paper presented in 36th Annual Congress of the European Society of Intensive Care Medicine, ESICM Lives 2023, Milan, 2023.
    Published
  2. Silva-Pereira, Carolina; Reina-Couto, M.; Alves, David; Pereira-Terra, Patricia; Martins, S; Teixeira-Santos, Luísa; Pinho, Dora; et al. "Proinflammatory and endothelial activation profiles in hospitalized COVID-19 patients: impact of arterial hypertension and previous treatment with renin-angiotensin-aldosterone inhibitors. Br J Pharmacol 2023; 180(S1):198-199 [P0895]". Paper presented in World Congress of Basic and Clinical Pharmacology 2023, Glasgow, 2023.
    Published
  3. Reina-Couto, M.; Pereira-Terra, Patricia; Silva-Pereira, Carolina; Quelhas-Santos Janete; Martins, S; Teixeira-Santos, Luísa; Pinho, Dora; et al. "Lipoxins profile and FPR2/ALX receptor expression in human acute heart failure and cardiogenic shock. Br J Pharmacol 2023; 180(S1):813-814 [P1023]". Paper presented in World Congress of Basic and Clinical Pharmacology 2023, Glasgow, 2023.
    Published
  4. Reina-Couto, M.; Silva-Pereira, Carolina; Pereira-Terra, Patricia; Quelhas-Santos Janete; Martins S; Teixeira-Santos, Luísa; Pinho, Dora; et al. "Inflammatory versus resolutive responses and endothelial dysfunction in critically ill patients: differences in cardiogenic shock, septic shock and critical COVID-19 profiles. Intensive Care Med Exp 2022; 10(Suppl 2):39 [001434]". Paper presented in 35th Annual Congress of the European Society of Intensive Care Medicine, ESICM Lives 2022, 2022.
    Published
  5. Reina-Couto, M.; Pereira-Terra, Patrícia; Silva-Pereira, Carolina; Quelhas-Santos, Janete; Serrão, Paula; Afonso, Joana; Martins, Sandra; et al. "Venoarterial extracorporeal membrane oxygenation appears to induce higher neutrophil-derived inflammation and oxidative stress at the end of the first week of hospitalization. Intensive Care Med Exp. 2021, 9 (Suppl 1): 51 [001064]". Paper presented in 34th Annual Congress of the European Society of Intensive Care Medicine - ESICM Lives 2021, Digital, 2021., 2021.
    Published • https://doi.org/10.1186/s40635-021-00413-8
  6. Reina-Couto, M.; Silva-Pereira, Carolina; Pereira-Terra, Patrícia; Quelhas-Santos Janete; Bessa, João; Marques, C; Serrão, Paula; et al. "Endocan - a potential new biomarker of inflammation-driven "endothelitis" in human acute heart failure and cardiogenic shock. Rev Port Cardiol. 2021; 40(Espec Congr):75-76.". Paper presented in Congresso Português de Cardiologia 2021 (CPC 2021), 2021.
    Published
  7. Reina-Couto, Marta; Silva-Pereira, Carolina; Terra, Patrícia; Quelhas-Santos, Janete; Pinho, Dora; Martins, Sandra; Serrão, Paula; et al. "Proinflammatory cytokines and endothelial cell activation in human acute heart failure versus septic shock. Intensive Care Med Exp. 2020, 8(2): 73 [001521]". Paper presented in 33rd Annual Congress of the European Society of Intensive Care Medicine, ESICM Lives 2020, Digital, 2020.
    Published • https://doi.org/10.1186/s40635-020-00354-8
  8. Silva-Pereira, Carolina; Reina-Couto, Marta; Quelhas-Santos, Janete; Sousa-Oliveira, Ana; Duarte, Álvaro; Pinho, Dora (6B14-8877-6AD9); Serrão, Paula; et al. "Lipoxin profiles in human acute heart failure and cardiogenic shock and their modulation by aspirin or statin therapy. Eur J Clin Invest. 2020, 50(Suppl. 1):43. [54ASM-0234]". Paper presented in European Society for Clinical Investigation (ESCI) Virtual Meeting 2020 - COVID Edition, 2020.
    Published
  9. Couto, Marta; Silva-Pereira, Carolina; Quelhas-Santos, Janete; Pinho, Dora (6B14-8877-6AD9); Martins, Sandra; Serrão, Paula; Afonso, Joana; et al. "Proinflammatory cytokines and endothelial cell activation in human acute heart failure and cardiogenic shock. Eur J Clin Invest. 2020; 50(Suppl. 1):44-45. [54ASM-0267]". Paper presented in European Society for Clinical Investigation (ESCI) Virtual Meeting 2020 - COVID Edition, 2020.
    Published • http://doi.org/10.1111/eci.13369
  10. Reina-Couto, Marta; Silva-Pereira, Carolina; Bessa, João; Oliveira-Santos, Marisa; Serrão, Paula; Afonso, Joana; Roncon-Albuquerque, Roberto; Paiva, José Artur; Sousa, Teresa. "Inflammation and resolution of inflammation in human acute heart failure. Intensive Care Med Exp. 2019, 7(Suppl 3):001499.". Paper presented in 32nd Annual Congress of the European Society of Intensive Care Medicine (ESICM Lives 2019), Berlin, 2019.
    Published • 10.1016/s1567-4215(05)80373-x
  11. Reina-Couto, Marta; Bessa, João Pedro; Oliveira-Santos, Marisa; Serrão, Paula; Afonso, Joana; Roncon-Albuquerque, Roberto; Paiva, José Artur; Albino-Teixeira, António; Sousa, Teresa. "Resolvins in human acute heart failure. Eur J Clin Invest. 2019, 49(Suppl. 1):204-205.[083-F]". Paper presented in 53rd Annual Scientific Meeting of the European Society for Clinical Investigation (ESCI), “The Clocks of Metabolism and Disease”, 2019, Coimbra, 2019.
    Published • http://dx.doi.org/10.1111/eci.13109
  12. Reina-Couto, Marta; Bessa, João Pedro; Oliveira-Santos, Marisa; Serrão, Paula; Afonso, Joana; Roncon-Albuquerque, Roberto; Paiva, José Artur; Albino-Teixeira, António; Sousa, Teresa. "Endocan and resolvin-D1 association with ventricular dysfunction, lactic acidosis and prognostic scores in human acute heart failure. Eur J Heart Failure 2019, 21 (Suppl. S1): 114 [P476]". Paper presented in Heart Failure 2019, Athens, 2019.
    Published • https://doi.org/10.1002/ejhf.1488
  13. Reina-Couto, Marta; Bessa, João; Serrão, Paula; Afonso, Joana; Roncon-Albuquerque, Roberto; Paiva, José Artur; Albino-Teixeira, António; Sousa, Teresa. "Endocan and resolvin D1: two novel biomarkers for the management of acute heart failure? Intensive Care Med Exp. 2018, 6 (Suppl. 2): 1001.". Paper presented in 31st Annual Congress of the European Society of Intensive Care Medicine, ESICM Lives 2018, Paris, 2018.
    Published • https://doi.org/10.1186/s40635-018-0201-6
  14. Reina-Couto, M.; Bessa, J.P.; Serrão, P.; Afonso, J.; Roncon-Albuquerque, R.; Paiva, J. Artur; Albino-Teixeira, A.; Sousa, T.. "Inflammation resolution mediators in acute heart failure. J Hypertens. 2018, 36 (e-Supplement 1): e211.". Paper presented in 28th European Meeting on Hypertension and Cardiovascular Protection, Barcelona, 2018.
    Published • http://doi.org/10.1097/01.hjh.0000539595.60360.5f
  15. Reina-Couto, Marta; Bessa, João; Serrão, Paula; Afonso, Joana; Roncon-Albuquerque, Roberto; Paiva, José Artur; Albino-Teixeira, António; Sousa, Teresa. "Endocan as a new biomarker of severity in acute heart failure. Eur J Heart Failure 2018, 20 (Suppl. S1): 113 [P459].". Paper presented in Heart Failure 2018 and Word Congress on Acute Heart Failure, Vienna, 2018.
    Published
  16. Reina-Couto, Marta; Sousa, Teresa; Morato, Manuela; Afonso, Joana; Carvalho, Jorge; Fernandes, FB; Leite, VP; et al. "Interrelationship between renin-angiotensin-aldosterone system and oxidative stress in chronic heart failure patients with impaired renal function. Eur J Heart Failure 2017, 19 (Suppl. S1): 570 [P2219].". Paper presented in Heart Failure 2017 and 4th World Congress on Acute Heart Failure, Paris, 2017.
    Published
  17. Reina-Couto, Marta; Sousa, Teresa; Morato, Manuela; Carvalho, Jorge; Afonso, Joana; Bettencourt, Paulo; Albino-Teixeira, António. "Higher urinary hydrogen peroxide levels are associated with increased plasma renin activity and aldosterone concentration in patients with chronic heart failure. Eur J Heart Fail 2016, 18 (Suppl. 1): 495 [P2030].". Paper presented in Heart Failure 2016, Florence, 2016.
    Published
Conference paper
  1. Sousa, Teresa; Morato, Manuela; Pinho, Dora; Fernandes, Eduarda; Carvalho, Félix; Albino-Teixeira, António. "Increased oxidative stress in the mesenteric artery from hypertensive rats with activation of the renin-angiotensin system. In: Martins e Silva J, Saldanha C, Oliveira V, Prie A, Shore A (eds). Proceedings of the 23rd Conference of Microcirculation, Medimond Publishing CO, pp 137-140. ISBN: 88-7587-078-0.". Paper presented in 23rd Conference of Microcirculation, 2004.
    Published
  2. Sousa, Teresa; Fernandes, Eduarda; Morato, Manuela; Carvalho, Félix; Albino-Teixeira, António. "Antioxidant enzyme activity in mesenteric artery from DPSPX (1,3-dipropyl-8-sulfophenylxanthine)-hypertensive rats. In: Tooke J, Shore A, Whatmore J (Eds). The Microcirculation and Vascular Biology, Proceedings of the 22nd Meeting of the European Society for Microcirculation. Medimond SRL, pp 267-270. ISBN: 88-323-2828-3.". Paper presented in 22nd Meeting of the European Society for Microcirculation, 2002.
    Published
Conference poster
  1. Reina-Couto, Marta; Pereira-Terra, Patricia; Silva-Pereira, Carolina; Quelhas-Santos, Janete; Martins, Sandra; Teixeira-Santos, Luísa; Pinho, Dora; et al. "The lipoxin receptor FPR2/ALX is associated with lower inflammation and better prognosis in human acute heart failure". Paper presented in 9th European Workshop on Lipid Mediators, 2024.
  2. Silva-Pereira, Carolina; Reina-Couto, Marta; Teixeira-Santos, Luísa; Pereira-Terra, Patricia; Martins, Sandra; Pinho, Dora; Soares, Miguel Luz ; et al. "Dysregulation of Resolvin E1-Chemerin1 axis in critical COVID-19 patients". Paper presented in 9th European Workshop on Lipid Mediators, 2024.
  3. Teixeira-Santos, Luísa; Veríssimo, Eduardo; Martins, Sandra; Guimarães, João Tiago; Sousa, Teresa; Albino-Teixeira, António (591E-E938-3FF8); Pinho, Dora. "NADPH oxidase isoform-2 inhibitor GSK2795039 attenuates mechanical allodynia and transiently decreases microglial activation in a mouse model of peripheral nerve injury.". 2022.
  4. Teixeira-Santos, Luísa; Sousa, Teresa; Albino-Teixeira, A; Pinho, Dora. "Oral treatment with the pro-resolution mediator maresin1 ameliorates mechanical allodynia and reduces glial activation in a neuropathic pain mouse model. [ID:150]". Paper presented in 8th European Virtual Congress of Pharmacology (EPHAR 2021), 2021.
  5. Teixeira-Santos, Luísa; Pinho, Dora; Reina-Couto, Marta; Silva-Pereira, Carolina; Pereira-Terra, Patrícia; Dias, Andreia; Cordeiro, Gonçalo ; et al. "Increased urinary isoprostanes are associated with severity and mortality in COVID-19 patients. [ID:505]". Paper presented in 8th European Virtual Congress of Pharmacology (EPHAR 2021), 2021.
  6. Ferreira-Duarte, Mariana; Reina-Couto, Marta; Silva-Pereira, Carolina; Pereira-Terra, Patrícia; Teixeira-Santos, Luísa; Pinho, Dora; Sarmento, António; et al. "Angiotensin-converting enzyme 2 (ACE2) activity in COVID-19 patients: a study throughout hospitalization in different stages of disease severity. [ID:514]". Paper presented in 8th European Virtual Congress of Pharmacology (EPHAR 2021), 2021.
  7. Teixeira-Santos, Luísa; Veríssimo, Eduardo; Sousa, Teresa; Albino-Teixeira, António (591E-E938-3FF8); Pinho, Dora. "Therapeutic effect of NADPH oxidase isoform-2 inhibition in spared nerve injury-induced neuropathic pain: assaying behavioural approaches for assessment of spontaneous pain responses in C57BL/6 mice. [NCB-28]". 2021.
  8. Teixeira-Santos, Luísa; Veríssimo, Eduardo; Sousa, Teresa; Albino-Teixeira, Antonio; Pinho, Dora. "NADPH oxidase isoform-2 inhibition differentially affects pain responses in male and female mice with neuropathic pain. [ID: 1038062]". 2021.
  9. Teixeira-Santos, Luísa; Sousa, Teresa; Albino-Teixeira, António (591E-E938-3FF8); Pinho, Dora. "Voluntary oral intake of the pro-resolution mediator maresin 1 attenuates mechanical allodynia in the spared nerve injury model of neuropathic pain. [P408]". 2019.
Journal article
  1. Ferreira-Duarte, Mariana; Oliveira, Lilian Caroline Gonçalves; Quintas, Clara; Dias-Pereira, Patricia; Sousa, Teresa; Magro, Fernando; Casarini, Dulce Elena; Duarte-Araújo, Margarida; Morato, Manuela. "Angiotensin-converting enzymes 1 and 2 in the feces: presence and catalytic activity in the rat 2,4,6-trinitrobenzene sulfonic acid-induced model of colitis". Journal of Gastroenterology and Hepatology 39 9 (2024): 1885-1894. http://dx.doi.org/10.1111/jgh.16541.
    10.1111/jgh.16541
  2. Godinho, Nelson; Morato, Manuela; Albino-Teixeira, António; Caldas Afonso, Alberto; Sousa, Teresa; Correia-Costa, Liane. "Gender-related differences in cardiometabolic risk factors and oxidative stress among prepubertal children with obesity". Journal of Pediatric Endocrinology and Metabolism 37 1 (2023): 42-51. http://dx.doi.org/10.1515/jpem-2023-0286.
    Published • 10.1515/jpem-2023-0286
  3. Teixeira-Santos, Luísa; Martins, Sandra; Sousa, Teresa; Albino-Teixeira, António; Pinho, Dora. "The pro-resolving lipid mediator Maresin 1 ameliorates pain responses and neuroinflammation in the spared nerve injury-induced neuropathic pain: A study in male and female mice". PLOS ONE 18 6 (2023): e0287392. http://dx.doi.org/10.1371/journal.pone.0287392.
    Open access • Published • 10.1371/journal.pone.0287392
  4. Ferreira-Duarte, Mariana; Oliveira, Lilian Caroline Gonçalves; Quintas, Clara; Esteves-Monteiro, Marisa; Duarte-Araújo, Margarida; Sousa, Teresa; Casarini, Dulce Elena; Morato, Manuela. "ACE and ACE2 catalytic activity in the fecal content along the gut". Neurogastroenterology & Motility 35 9 (2023): http://dx.doi.org/10.1111/nmo.14598.
    Published • 10.1111/nmo.14598
  5. Sousa, Teresa; Pinho, Dora; Recchiuti, Antonio; Isopi, Elisa; Verri, Waldiceu A.. "Editorial: Specialized proresolving mediators: Benefits within and beyond inflammation resolution in cardiometabolic, neurological and psychiatric disorders". Frontiers in Physiology 14 (2023): http://dx.doi.org/10.3389/fphys.2023.1176700.
    Open access • 10.3389/fphys.2023.1176700
  6. Teixeira-Santos, Luísa; Veríssimo, Eduardo; Martins, Sandra; Sousa, Teresa; Albino-Teixeira, António; Pinho, Dora. "Effects of NADPH Oxidase Isoform-2 (NOX2) Inhibition on Behavioral Responses and Neuroinflammation in a Mouse Model of Neuropathic Pain". Biomedicines 11 2 (2023): 416. http://dx.doi.org/10.3390/biomedicines11020416.
    Published • 10.3390/biomedicines11020416
  7. Gaspar, Ana R.; Andrade, Beatriz; Mosca, Sara; Ferreira-Duarte, Mariana; Teixeira, Ana; Cosme, Dina; Albino-Teixeira, António; et al. "Association between blood pressure and angiotensin-converting enzymes activity in prepubertal children*". Journal of Hypertension 41 4 (2023): 545-553. http://dx.doi.org/10.1097/hjh.0000000000003345.
    Published • 10.1097/hjh.0000000000003345
  8. Reina-Couto, Marta; Roboredo-Madeira, Mariana; Pereira-Terra, Patrícia; Silva-Pereira, Carolina; Martins, Sandra; Teixeira-Santos, Luísa; Pinho, Dora; et al. "Evaluation of urinary cysteinyl leukotrienes as biomarkers of severity and putative therapeutic targets in COVID-19 patients". Inflammation Research 72 3 (2023): 475-491. http://dx.doi.org/10.1007/s00011-022-01682-z.
    Open access • 10.1007/s00011-022-01682-z
  9. Reina-Couto, Marta; Santos-Oliveira, Marisa; Pereira-Terra, Patrícia; Silva-Pereira, Carolina; Quelhas-Santos, Janete; Duarte, Álvaro; Martins, Sandra; et al. "Urinary Cysteinyl Leukotrienes as Biomarkers of Endothelial Activation, Inflammation and Oxidative Stress and Their Relationship with Organ Dysfunction in Human Septic Shock". Biomedicines 10 11 (2022): 2845. http://dx.doi.org/10.3390/biomedicines10112845.
    Open access • Published • 10.3390/biomedicines10112845
  10. Reina-Couto, Marta; Silva-Pereira, Carolina; Pereira-Terra, Patrícia; Quelhas-Santos, Janete; Bessa, João; Serrão, Paula; Afonso, Joana; et al. "Endothelitis profile in acute heart failure and cardiogenic shock patients: Endocan as a potential novel biomarker and putative therapeutic target". Frontiers in Physiology 13 (2022): 965611. http://dx.doi.org/10.3389/fphys.2022.965611.
    Open access • Published • 10.3389/fphys.2022.965611
  11. Reina-Couto, Marta; Pereira-Terra, Patrícia; Quelhas-Santos Janete; Silva-Pereira, Carolina; Albino-Teixeira, Antonio; Sousa, Teresa. "Inflammation in Human Heart Failure: Major Mediators and Therapeutic Targets". Frontiers in Physiology 12 (2021): http://dx.doi.org/10.3389/fphys.2021.746494.
    Published • 10.3389/fphys.2021.746494
  12. Ferreira-Duarte M; Rodrigues-Pinto T; Sousa T; Faria MA; Rocha MS; Menezes-Pinto D; Esteves-Monteiro M; et al. "Interaction between the Renin-Angiotensin System and Enteric Neurotransmission Contributes to Colonic Dysmotility in the TNBS-Induced Model of Colitis.". International journal of molecular sciences (2021): http://europepmc.org/abstract/med/34063607.
    10.3390/ijms22094836
  13. Leite-Almeida, Laura; Morato, Manuela; Cosme, Dina; Afonso, Joana; Areias, José C.; Guerra, António; Caldas Afonso, Alberto; et al. "Impact of physical activity on redox status and nitric oxide bioavailability in nonoverweight and overweight/obese prepubertal children". Free Radical Biology and Medicine 163 (2021): 116-124. http://dx.doi.org/10.1016/j.freeradbiomed.2020.12.005.
    10.1016/j.freeradbiomed.2020.12.005
  14. Reina-Couto, Marta; Afonso, Joana; Carvalho, Jorge; Morgado, Luís; Ronchi, Fernanda Aparecida; de Oliveira Leite, Ana Paula; Dias, Cláudia Camila; et al. "Interrelationship between renin-angiotensin-aldosterone system and oxidative stress in chronic heart failure patients with or without renal impairment". Biomedicine & Pharmacotherapy 133 (2021): 110938. http://dx.doi.org/10.1016/j.biopha.2020.110938.
    10.1016/j.biopha.2020.110938
  15. Patinha, Daniela; Abreu, Carla; Carvalho, Carla; Cunha, Olga Mariana; Mota, Mariana; Afonso, Joana; Sousa, Teresa; et al. "Adenosine A2A and A3 Receptors as Targets for the Treatment of Hypertensive-Diabetic Nephropathy". Biomedicines 8 11 (2020): 529. http://dx.doi.org/10.3390/biomedicines8110529.
    10.3390/biomedicines8110529
  16. Bessa, João; Albino-Teixeira, António; Reina-Couto, Marta; Sousa, Teresa. "Endocan: A novel biomarker for risk stratification, prognosis and therapeutic monitoring in human cardiovascular and renal diseases". Clinica Chimica Acta 509 (2020): 310-335. http://dx.doi.org/10.1016/j.cca.2020.07.041.
    10.1016/j.cca.2020.07.041
  17. Ferreira-Duarte, Mariana; Sousa, Joana Beatriz; Diniz, Carmen; Sousa, Teresa; Duarte-Araújo, Margarida; Morato, Manuela. "Experimental and Clinical Evidence of Endothelial Dysfunction in Inflammatory Bowel Disease". Current Pharmaceutical Design 26 30 (2020): 3733-3747. http://dx.doi.org/10.2174/1381612826666200701212414.
    Published • 10.2174/1381612826666200701212414
  18. Leal, Joana; Teixeira-Santos, Luísa; Pinho, Dora; Afonso, Joana; Carvalho, Jorge; de Lourdes Bastos, Maria; Albino-Teixeira, António; Fraga, Sónia; Sousa, Teresa. "l-proline supplementation improves nitric oxide bioavailability and counteracts the blood pressure rise induced by angiotensin II in rats". Nitric Oxide 82 (2019): 1-11. http://dx.doi.org/10.1016/j.niox.2018.10.007.
    Published • 10.1016/j.niox.2018.10.007
  19. Adlbrecht, Christopher; Blanco-Verea, Alejandro; Bouzas-Mosquera, María C.; Brion, María; Burtscher, Martin; Carbone, Federico; Chang, Ting-Ting; et al. "Research update for articles published in EJCI in 2016". European Journal of Clinical Investigation 48 10 (2018): e13016. http://dx.doi.org/10.1111/eci.13016.
    Published • 10.1111/eci.13016
  20. Costa, Ana Catarina; Reina-Couto, Marta; Albino-Teixeira, António; Sousa, Teresa. "Aspirin and blood pressure: Effects when used alone or in combination with antihypertensive drugs". Revista Portuguesa de Cardiologia 36 7-8 (2017): 551-567. http://dx.doi.org/10.1016/j.repc.2017.05.008.
    Published • 10.1016/j.repc.2017.05.008
  21. Morato, Manuela; Correia-Costa, Liane; Sousa, Teresa; Cosme, Dina; Schaefer, Franz; Areias, José Carlos; Guerra, António; et al. "Longer duration of obesity is associated with a reduction in urinary angiotensinogen in prepubertal children". Pediatric Nephrology 32 8 (2017): 1411-1422. http://dx.doi.org/10.1007/s00467-017-3639-y.
    Published • 10.1007/s00467-017-3639-y
  22. Agra, Rosa María; Al-Daghri, Nasser M.; Badimon, Lina; Bodi, Vicente; Carbone, Federico; Chen, Mao; Cubedo, Judit; et al. "Research update for articles published in EJCI in 2014". European Journal of Clinical Investigation 46 10 (2016): 880-894. http://dx.doi.org/10.1111/eci.12671.
    Published • 10.1111/eci.12671
  23. Correia-Costa, Liane; Sousa, Teresa; Morato, Manuela; Cosme, Dina; Afonso, Joana; Areias, José C.; Schaefer, Franz; et al. "Oxidative stress and nitric oxide are increased in obese children and correlate with cardiometabolic risk and renal function". British Journal of Nutrition 116 5 (2016): 805-815. http://dx.doi.org/10.1017/s0007114516002804.
    Published • 10.1017/s0007114516002804
  24. Reina-Couto, Marta; Vale, Luís; Carvalho, Jorge; Bettencourt, Paulo; Albino-Teixeira, António; Sousa, Teresa. "Resolving Inflammation in Heart Failure: Novel Protective Lipid Mediators". Current Drug Targets 17 10 (2016): 1206-1223. http://dx.doi.org/10.2174/1389450117666160101121135.
    Published • 10.2174/1389450117666160101121135
  25. Costa, Sónia; Reina-Couto, Marta; Albino-Teixeira, António; Sousa, Teresa. "Statins and oxidative stress in chronic heart failure". Revista Portuguesa de Cardiologia 35 1 (2016): 41-57. http://dx.doi.org/10.1016/j.repc.2015.09.006.
    Published • 10.1016/j.repc.2015.09.006
  26. Correia-Costa, Liane; Sousa, Teresa; Morato, Manuela; Cosme, Dina; Afonso, Joana; Moura, Cláudia; Mota, Cláudia; et al. "Association of myeloperoxidase levels with cardiometabolic factors and renal function in prepubertal children". European Journal of Clinical Investigation 46 1 (2015): 50-59. http://dx.doi.org/10.1111/eci.12564.
    Published • 10.1111/eci.12564
  27. Correia-Costa, Liane; Morato, Manuela; Sousa, Teresa; Cosme, Dina; Guimarães, João Tiago; Guerra, António; Schaefer, Franz; et al. "Urinary fibrogenic cytokines ET-1 and TGF-ß1 are associated with urinary angiotensinogen levels in obese children". Pediatric Nephrology 31 3 (2015): 455-464. http://dx.doi.org/10.1007/s00467-015-3232-1.
    Published • 10.1007/s00467-015-3232-1
  28. Correia-Costa, Liane; Cosme, Dina; Nogueira-Silva, Luís; Morato, Manuela; Sousa, Teresa; Moura, Cláudia; Mota, Cláudia; et al. "Gender and obesity modify the impact of salt intake on blood pressure in children". Pediatric Nephrology 31 2 (2015): 279-288. http://dx.doi.org/10.1007/s00467-015-3210-7.
    Published • 10.1007/s00467-015-3210-7
  29. Patinha, Daniela; Afonso, Joana; Sousa, Teresa; Morato, Manuela; Albino-Teixeira, António. "Diabetes-induced increase of renal medullary hydrogen peroxide and urinary angiotensinogen is similar in normotensive and hypertensive rats". Life Sciences 108 2 (2014): 71-79. http://dx.doi.org/10.1016/j.lfs.2014.05.011.
    Published • 10.1016/j.lfs.2014.05.011
  30. Reina-Couto, Marta; Carvalho, Jorge; Valente, Maria João; Vale, Luís; Afonso, Joana; Carvalho, Félix; Bettencourt, Paulo; Sousa, Teresa; Albino-Teixeira, António. "Impaired resolution of inflammation in human chronic heart failure". European Journal of Clinical Investigation 44 6 (2014): 527-538. http://dx.doi.org/10.1111/eci.12265.
    Published • 10.1111/eci.12265
  31. Patinha, Daniela; Afonso, Joana; Sousa, Teresa; Morato, Manuela; Albino-Teixeira, António. "Activation of adenosine receptors improves renal antioxidant status in diabetic Wistar but not SHR rats". Upsala Journal of Medical Sciences 119 1 (2013): 10-18. http://dx.doi.org/10.3109/03009734.2013.851748.
    Published • 10.3109/03009734.2013.851748
  32. Sousa, T; Oliveira, S; Afonso, J; Morato, M; Patinha, D; Fraga, S; Carvalho, F; Albino-Teixeira, A. "Role of H2O2 in hypertension, renin-angiotensin system activation and renal medullary disfunction caused by angiotensin II". British Journal of Pharmacology 166 8 (2012): 2386-2401. http://dx.doi.org/10.1111/j.1476-5381.2012.01957.x.
    Published • 10.1111/j.1476-5381.2012.01957.x
  33. Sousa, Teresa; Pinho, Dora; Morato, Manuela; Marques-Lopes, José; Fernandes, Eduarda; Afonso, Joana; Oliveira, Sofia; Carvalho, Félix; Albino-Teixeira, António. "Role of superoxide and hydrogen peroxide in hypertension induced by an antagonist of adenosine receptors". European Journal of Pharmacology 588 2-3 (2008): 267-276. http://dx.doi.org/10.1016/j.ejphar.2008.04.044.
    Published • 10.1016/j.ejphar.2008.04.044
  34. Morato, Manuela; Sousa, Teresa; Albino-Teixeira, António. "Purinergic receptors in the splanchnic circulation". Purinergic Signalling 4 3 (2008): 267-285. http://dx.doi.org/10.1007/s11302-008-9096-0.
    Published • 10.1007/s11302-008-9096-0
  35. Pinho, Dora; Morato, Manuela; Sousa, Teresa; Marques-Lopes, José; Tavares, Isaura; Albino-Teixeira, António. "Hipertensão e hipoalgesia: papel do bolbo raquidiano ventrolateral caudal e do sistema GABAérgico espinhal.". Revista Dor 15 2 (2007): 13-21. https://repositorio-aberto.up.pt/handle/10216/94725.
    Published
  36. Pinho, Dora; Sousa, Teresa; Morato, Manuela; Tavares, Isaura; Albino-Teixeira, António. "Lesion of the caudal ventrolateral medulla prevents the induction of hypertension by adenosine receptor blockade in rats". Brain Research 1073-1074 (2006): 374-382. http://dx.doi.org/10.1016/j.brainres.2005.12.098.
    Published • 10.1016/j.brainres.2005.12.098
  37. Morato, Manuela; Pinho, Dora; Sousa, Teresa; Guimarães, Serafim; Moura, Daniel; Albino-Teixeira, António. "Pre- and postjunctional effects of angiotensin II in hypertension due to adenosine receptor blockade". European Journal of Pharmacology 531 1-3 (2006): 209-216. http://dx.doi.org/10.1016/j.ejphar.2005.12.009.
    Published • 10.1016/j.ejphar.2005.12.009
  38. Morato, Manuela; Pinho, Dora; Sousa, Teresa; Tavares, Isaura; Albino-Teixeira, António. "Inhibition of nociceptive responses of spinal cord neurones during hypertension involves the spinal GABAergic system and a pain modulatory center located at the caudal ventrolateral medulla". Journal of Neuroscience Research 83 4 (2006): 647-655. http://dx.doi.org/10.1002/jnr.20770.
    Published • 10.1002/jnr.20770
  39. Sousa, Teresa; Fernandes, Eduarda; Nunes, Carla; Laranjinha, João; Carvalho, Félix; Pinho, Dora; Morato, Manuela; Albino-Teixeira, António. "Scavenging of nitric oxide by an antagonist of adenosine receptors". Journal of Pharmacy and Pharmacology 57 3 (2005): 399-404. http://dx.doi.org/10.1211/0022357055614.
    Published • 10.1211/0022357055614
  40. Sousa, Teresa; Morato, Manuela; Fernandes, Eduarda; Carvalho, Félix; Albino-Teixeira, António. "Xanthine Oxidase Inhibition by 1,3-dipropyl-8-sulfophenyl-xanthine (DPSPX), an Antagonist of Adenosine Receptors". Journal of Enzyme Inhibition and Medicinal Chemistry 19 1 (2004): 11-15. http://dx.doi.org/10.1080/14756360310001634910.
    Published • 10.1080/14756360310001634910
  41. Guimaraes, Serafim; Morato, Manuela; Sousa, Teresa; Albino-Teixeira, Antonio. "Hypertension Due to Blockade of Adenosine Receptors". Pharmacology and Toxicology 92 4 (2003): 160-162. http://dx.doi.org/10.1034/j.1600-0773.2003.920404.x.
    Published • 10.1034/j.1600-0773.2003.920404.x
  42. Morato, M.; Sousa, T.; Guimaraes, S.; Moura, D.; Albino-Teixeira, A.. "Losartan and atenolol on hypertension induced by adenosine receptor blockade". Autonomic and Autacoid Pharmacology 23 2 (2003): 133-140. http://dx.doi.org/10.1046/j.1474-8673.2003.00287.x.
    Published • 10.1046/j.1474-8673.2003.00287.x
  43. Morato, Manuela; Sousa, Teresa; Guimarães, Serafim; Moura, Daniel; Albino-Teixeira, António. "The role of angiotensin II in hypertension due to adenosine receptors blockade". European Journal of Pharmacology 455 2-3 (2002): 135-141. http://dx.doi.org/10.1016/s0014-2999(02)02587-6.
    Published • 10.1016/s0014-2999(02)02587-6
  44. Sousa, Teresa; Morato, Manuela; Albino-Teixeira, António. "Angiotensin converting enzyme inhibition prevents trophic and hypertensive effects of an antagonist of adenosine receptors". European Journal of Pharmacology 441 1-2 (2002): 99-104. http://dx.doi.org/10.1016/s0014-2999(02)01488-7.
    Published • 10.1016/s0014-2999(02)01488-7
Newsletter article
  1. Reina-Couto, Marta; Vale, Luís; Carvalho, Jorge; Sousa, Teresa; Bettencourt, Paulo; Albino-Teixeira, António. "Resolution of inflammation: The missing key to improve heart failure prognosis?", EurekAlert! , 2016, https://www.eurekalert.org/pub_releases/2016-09/bsp-roi090516.php.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2024/02/08 ACE and ACE2 activities in the feces of patients with inflammatory bowel disease on biological treatment 54th Meeting of the Portuguese Society of Pharmacology
Portuguese Society of Pharmacology (Lisbon, Portugal)
2024/02/08 Resolvin E1 is a major mediator of the inflammatory response in hospitalized COVID-19 patients 54th Meeting of the Portuguese Society of Pharmacology
Portuguese Society of Pharmacology (Lisbon, Portugal)
2023/09/25 Renin-angiotensin-aldosterone system in acute heart failure and cardiogenic shock. Seminar "Renin-angiotensin-aldosterone system in health and disease: new insights into a classic system."
Faculdade de Farmácia da Universidade do Porto (Portugal)
2023/09/25 Impact of hypertension and previous treatment with RAAS inhibitors in endothelial dysfunction in hospitalized COVID-19 patients. Seminar "Renin-angiotensin-aldosterone system in health and disease: new insights into a classic system."
Faculdade de Farmácia da Universidade do Porto (Porto, Portugal)
2023/09/25 Activity of angiotensin-converting enzymes (ACE and ACE2) in patients with COVID-19 of different severity. Seminar "Renin-angiotensin-aldosterone system in health and disease: new insights into a classic system."
Faculdade de Farmácia da Universidade do Porto (Porto, Portugal)
2023/09/25 ACE/ACE2 balance in the healthy and inflamed gut Seminar "Renin-angiotensin-aldosterone system in health and disease: new insights into a classic system."
Faculdade de Farmácia da Universidade do Porto (Porto, Portugal)
2023/09 Endothelial dysfunction in different stages of disease severity of COVID-19: focus on endocan and arterial hypertension. 18th YES Meeting 2023
(Porto, Portugal)
2023/02 Evaluation of urinary cysteinyl leukotrienes as biomarkers of severity and putative therapeutic targets in COVID-19 patients LIII Reunião Anual da Sociedade Portuguesa de Farmacologia
(Coimbra, Portugal)
2023/02 Oxidative stress association with COVID-19 severity and mortality: focus on urinary isoprostanes LIII Reunião Anual da Sociedade Portuguesa de Farmacologia
(Coimbra, Portugal)
2023/02 Endothelial dysfunction in different stages of COVID-19 severity. LIII Reunião Anual da Sociedade Portuguesa de Farmacologia
(Coimbra, Portugal)
2022/06 Resolution of inflammation versus proinflammatory status in human acute heart failure and cardiogenic shock 15th World Congress on Inflammation (WCI2022)
(Rome, Italy)
2022/05/17 Unresolved inflammation and endothelitis in severe and critically ill COVID-19 EUGLOHRIA Seeding Conference
EUGLOHRIA
2022/02/11 Effects of NADPH oxidase isoform-2 inhibition on behavioral responses and neuroinflammatory markers in a mouse model of neuropathic pain. LII Reunião da Sociedade Portuguesa de Farmacologia (SPF 2022)
Sociedade Portuguesa de Farmacologia (SPF) (Portugal)
2022/02/11 ACE2 in experimental colitis. LII Reunião da Sociedade Portuguesa de Farmacologia (SPF 2022)
Sociedade Portuguesa de Farmacologia (SPF) (Portugal)
2022/02/11 ACE2/ACE balance in COVID-19 patients with different disease severity. LII Reunião da Sociedade Portuguesa de Farmacologia (SPF 2022)
Sociedade Portuguesa de Farmacologia (SPF) (Portugal)
2022/02/09 Inflammatory cytokine response in moderate and severe COVID-19 patients and its relationship to prognosis. LII Reunião da Sociedade Portuguesa de Farmacologia (SPF 2022)
Sociedade Portuguesa de Farmacologia (SPF) (Portugal)
2022/02/09 Arachidonic acid derived proresolving or proinflammatory mediators and lipoxin receptor expression in human acute heart failure and cardiogenic shock LII Reunião da Sociedade Portuguesa de Farmacologia (SPF 2022)
Sociedade Portuguesa de Farmacologia (SPF) (Portugal)
2022/02/09 Impact of previous ß-blocker treatment on inflammatory status of acute heart failure and cardiogenic shock patients. LII Reunião da Sociedade Portuguesa de Farmacologia (SPF 2022)
Sociedade Portuguesa de Farmacologia (SPF) (Portugal)
2021/12/08 Comparison of endothelial activation profiles in critically ill patients with cardiogenic shock, septic shock and severe COVID-19. 8th European Virtual Congress of Pharmacology (EPHAR 2021)
EPHAR (Czech Republic)
2021/12/08 Inflammatory and resolution of inflammation responses in critically ill patients with cardiogenic shock, septic shock and severe COVID-19. 8th European Virtual Congress of Pharmacology (EPHAR 2021)
EPHAR (Czech Republic)
2021/12/08 Evaluation of serum and urinary lipoxin profiles and FPR2/ALX receptor expression in human acute heart failure, cardiogenic shock and septic shock. 8th European Virtual Congress of Pharmacology (EPHAR 2021)
EPHAR (Czech Republic)
2021/05 Endocan - a potential new biomarker of inflammation-driven "endothelitis" in human acute heart failure and cardiogenic shock. Congresso Português de Cardiologia 2021 (CPC 2021)
(Portugal)
2021/02/19 Urinary biomarkers of oxidative stress, inflammation and vascular dysfunction in septic shock patients and their relationship with organ dysfunction and prognosis. LI Reunião da Sociedade Portuguesa de Farmacologia
Universidade de Lisboa Faculdade de Farmácia (Portugal)
2021/02/18 Endothelial cell activation and proinflammatory status decrease during hospitalization in septic shock but not in cardiogenic shock. LI Reunião da Sociedade Portuguesa de Farmacologia
Universidade de Lisboa Faculdade de Farmácia (Portugal)
2021/02/18 Behavioral responses in a mouse model of neuropathic pain after systemic inhibition of NADPH oxidase isoform-2 (Nox2). LI Reunião da Sociedade Portuguesa de Farmacologia
Universidade de Lisboa Faculdade de Farmácia (Portugal)
2021/02/17 Resolution of inflammation in human acute heart failure and cardiogenic shock: role of resolvin D1 and E1. LI Reunião da Sociedade Portuguesa de Farmacologia
Universidade de Lisboa Faculdade de Farmácia
2020/09 Lipoxin profiles in human acute heart failure and cardiogenic shock and their modulation by aspirin or statin therapy. ESCI Virtual - COVID Edition 2020
2020/09 Proinflammatory cytokines and endothelial cell activation in human acute heart failure and cardiogenic shock. ESCI Virtual - COVID Edition 2020
2020/02 Serum and urinary lipoxins profiles in patients with acute heart failure and cardiogenic shock. L Reunião da Sociedade Portuguesa de Farmacologia
Sociedade Portuguesa de Farmacologia (Coimbra, Portugal)
2020/02 Comparison of the inflammatory profile in patients with cardiogenic shock or septic shock. L Reunião da Sociedade Portuguesa de Farmacologia
Sociedade Portuguesa de Farmacologia (Coimbra, Portugal)
2019/09 Endocan, a novel endothelial dysfunction biomarker, is associated with ventricular dysfunction, inflammation and worse hemodynamics in human acute heart failure. YES Meeting 2019
Universidade do Porto Faculdade de Medicina (Porto, Portugal)
2019 Endothelial dysfunction and inflammation resolving mediators in human acute heart failure. XLIX Reunião da Sociedade Portuguesa de Farmacologia
Sociedade Portuguesa de Farmacologia (Porto, Portugal)
2019 Specialized proresolving mediators (SPMs) in human acute heart failure (AHF). 1ª Reunião do Programa Doutoral em Farmacologia e Toxicologia Experimental e Clínica
Universidade do Porto Faculdade de Medicina (Porto, Portugal)
2018 Endocan and resolvin D1: two novel biomarkers for the management of acute heart failure? 31st Annual Congress of the European Society of Intensive Care Medicine – ESICM LIVES 2018
European Society of Intensive Care Medicine (Paris, France)
2016 The attenuation of the hypertensive effect of angiotensin II by L-proline is probably linked to its ability to decrease asymmetric dimethylarginine. XLVI Reunião da Sociedade Portuguesa de Farmacologia
Sociedade Portuguesa de Farmacologia (Porto, Portugal)
2015 L-proline supplementation attenuates the development of arterial hypertension induced by angiotensin II. XLV Reunião da Sociedade Portuguesa de Farmacologia
Sociedade Portuguesa de Farmacologia (Lisboa, Portugal)
2014/06 Low-dose aspirin improves renal function and antihypertensive efficacy in hypertensive rats treated with losartan. 3rd International Conference on Nephrology & Therapeutics
OMICS International (Valencia, Spain)
2013 Anti-inflammatory lipoxins in patients with chronic heart failure and their modulation by low-dose acetylsalicylic acid. 47th Annual Scientific Meeting of the European Society for Clinical Investigation
European Society for Clinical Investigation (Albufeira, Portugal)
2013 Anti-inflammatory lipid mediators in cardiovascular diseases: impact of aspirin. Seminários FMUP
Universidade do Porto Faculdade de Medicina (Porto, Portugal)
2012 Hydrogen peroxide regulates renal production of renin and angiotensinogen in angiotensin II-hypertensive rats. XLII Reunião da Sociedade Portuguesa de Farmacologia
Reunião da Sociedade Portuguesa de Farmacologia (Lisboa, Portugal)
2011 Polyethylene glycol catalase reduces the renal medullary expression of Nox4 and AT1 receptor but markedly increases systemic angiotensinogen levels in angiotensin II-infused rats. 21st European Meeting on Hypertension and Cardiovascular Prevention
European Society of Hypertension (Milan, Italy)
2011 Counterregulatory mechanisms involved in the blunted antihypertensive response to polyethyleneglycol catalase in angiotensin II-infused rats. XLI Reunião Anual da Sociedade Portuguesa de Farmacologia
Sociedade Portuguesa de Farmacologia (Coimbra, Portugal)
2010 Lack of sustained antihypertensive effect of polyethylene glycol catalase treatment in angiotensin II-hypertensive rats. 20th European Meeting on Hypertension
European Society of Hypertension (Oslo, Norway)
2010 Oxidative stress and disease. VI Dia de Biologia Marinha e Biotecnologia
Escola Superior de Turismo e Tecnologia do Mar, Instituto Politécnico de Leiria (Peniche, Portugal)
2009 The renal medulla is a major target for redox dysfunction and altered nuclear signalling in angiotensin II (Ang II)-dependent hypertension. 19th European Meeting on Hypertension
European Society of Hypertension (Milan, Italy)
2009 A hipertensão arterial causada pela angiotensina II está associada a um aumento da produção de H2O2 e a alterações da sinalização celular na medula renal. 3º Congresso Português de Hipertensão
Sociedade Portuguesa de Hipertensão (Vilamoura, Portugal)
2009 Short-term antihypertensive effectiveness of polyethylene glycol catalase treatment in angiotensin II-hypertensive rats. XL Reunião Anual da Sociedade Portuguesa de Farmacologia
Sociedade Portuguesa de Farmacologia (Porto, Portugal)
2008 Increased H2O2 production in the renal medulla of angiotensin II-hypertensive rats, through a NADPH oxidase mediated pathway. XXXIX Reunião Anual da Sociedade Portuguesa de Farmacologia
Sociedade Portuguesa de Farmacologia (Lisboa, Portugal)
2007 Produção de peróxido de hidrogénio (H2O2) em dois modelos de hipertensão arterial com aumento da angiotensina II. 1º Congresso Português de Hipertensão
Sociedade Portuguesa de Hipertensão (Vilamoura, Portugal)
2007 Apocynin, but not tempol, prevents the rise in vascular and urinary levels of H2O2 induced by chronic infusion of 1,3-dipropyl-8-sulfophenylxanthine (DPSPX). XXXVIII Reunião Anual da Sociedade Portuguesa de Farmacologia
Sociedade Portuguesa de Farmacologia (Coimbra, Portugal)
2006 Vascular and systemic redox dysfunction in hypertension due to blockade of adenosine receptors. Xth Workshop of the ESH Young Investigator Initiative Group, 16th European Meeting of Hypertension
European Society of Hypertension (Madrid, Spain)
2005 Apocynin, but not tempol, attenuates the hypertension and increases vascular antioxidant defenses in rats with activation of the renin-angiotensin system. Young Investigators Initiative, 15th European Meeting of Hypertension
European Society of Hypertension (Milan, Italy)
2005 Increased oxidative stress in a model of hypertension with activation of the renin-angiotensin system. XXXVI Reunião Anual da Sociedade Portuguesa de Farmacologia
Sociedade Portuguesa de Farmacologia (Lisboa, Portugal)
2005 NADPH oxidase and hydrogen peroxide mediate vascular hyperplasia and hypertension in rats with activation of the renin-angiotensin system. XXXVI Reunião Anual da Sociedade Portuguesa de Farmacologia
Sociedade Portuguesa de Farmacologia (Lisboa, Portugal)
2004 Antioxidant enzyme activity in resistance and conduit vessels from hypertensive rats with activation of the renin-angiotensin system. EPHAR 2004
EPHAR/Sociedade Portuguesa de Farmacologia (Porto, Portugal)
2003 Vascular antioxidant enzyme activity in renovascular hypertensive rats. Young Investigators Initiative, 13th European Meeting on Hypertension
European Society of Hypertension (Milan, Italy)
2003 Comparison of vascular glutathione peroxidase activity in 1,3-dipropyl-8-sulphophenylxanthine hypertensive rats and in renovascular hypertension. 11th Porto Meeting on Adrenergic Mechanisms
Universidade do Porto Faculdade de Medicina (Porto, Portugal)
2003 Papel da activação do sistema renina-angiotensina na disfunção redox vascular. [Apresentação do projecto premiado. ] Prémio Jovem Investigador – Programa Gulbenkian de Estímulo à Investigação 2002
Fundação Calouste Gulbenkian (Lisboa, Portugal)
2003 Actividade antioxidante na artéria mesentérica e na aorta num modelo de hipertensão com activação do sistema renina-angiotensina. IX Reunião da Associação Portuguesa de Hipertensão
Associação Portuguesa de Hipertensão (Sintra, Portugal)
2003 Comparison of antioxidant enzyme activity in arteries and veins from renovascular hypertensive rats. XXXIV Reunião da Sociedade Portuguesa de Farmacologia
Reunião da Sociedade Portuguesa de Farmacologia (Coimbra, Portugal)
2002 Estudo do efeito de alguns derivados xantínicos sobre o monóxido de azoto. VIII Reunião da Associação Portuguesa de Hipertensão
Associação Portuguesa de Hipertensão (Vidago, Portugal)
2002 Vascular antioxidant enzyme activity in hypertension caused by blockade of adenosine receptors. XXXIII Reunião da Sociedade Portuguesa de Farmacologia
Reunião da Sociedade Portuguesa de Farmacologia. (Lisboa, Portugal)
2001 Prevention of 1,3-dipropyl-8-sulfophenylxanthine-induced hypertension by losartan and atenolol. Fifth WorkShop of the Young Investigator Initiative Group, Eleventh European Meeting on Hypertension
European Society of Hypertension (Milan, Italy)
2001 Scavenging effect of DPSPX (1,3-dipropyl-8-sulfophenylxanthine) on nitric oxide. XXXII Reunião da Sociedade Portuguesa de Farmacologia
Sociedade Portuguesa de Farmacologia (Coimbra, Portugal)
2000 Effects of losartan and atenolol in DPSPX (1,3-dipropyl-8-sulfophenylxanthine)-induced hypertension. 10th Porto Meeting on Adrenergic Mechanisms
Universidade do Porto Faculdade de Medicina (Porto, Portugal)
2000 Antihypertensive effects of losartan and atenolol in 1,3-dipropyl-8-sulfophenylxanthine (DPSPX)-induced hypertension. XXXI Reunião da Sociedade Portuguesa de Farmacologia
Sociedade Portuguesa de Farmacologia (Porto, Portugal)
1999 Radiofármacos - Características e Boas Práticas de Manipulação. 2as Jornadas Transmontanas de Farmácia
2as Jornadas Transmontanas de Farmácia (Chaves, Portugal)
1999 Losartan prevents 1,3-dipropyl-8-sulfophenylxanthine (DPSPX)-induced hypertension. XXX Reunião da Sociedade Portuguesa de Farmacologia
Sociedade Portuguesa de Farmacologia (Lisboa, Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2020/10/01 - Current Adrenergic regulation of resolution of inflammation and endothelial function in human acute heart failure and cardiogenic shock
Supervisor of Carolina Isabel Ribeiro da Silva Pereira
 Programa Doutoral em Farmacologia e Toxicologia Experimental e Clínicas (PhD)
Universidade do Porto Faculdade de Medicina, Portugal
2016 - Current Resolution of inflammation in acute heart failure.
Co-supervisor of Marta Fernanda Reina Couto
 Programa Doutoral em Farmacologia e Toxicologia Experimentais e Clínicas (PhD)
Universidade do Porto Faculdade de Medicina, Portugal
2021/09/01 - 2022/07/01 Evaluation of urinary 11-dehydrothromboxane B2 as a biomarker of severity and putative therapeutic target in human acute heart failure.
Supervisor of Ana Isabel Sousa Oliveira
 Medicina (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2021/09/01 - 2022/06/17 Evolution of endocan and other endothelial dysfunction markers in COVID-19 patients with different stages of disease severity.
Supervisor of David André Rosário Alves
 Medicina (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2021/09/01 - 2022/05/26 Evaluation of urinary cysteinyl leukotrienes as biomarkers of severity and putative therapeutic targets in COVID-19 patients.
Supervisor of Mariana Simões de Carvalho Roboredo Madeira
 Medicina (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2020/09/01 - 2021/06/22 Urinary cysteinyl leukotrienes as biomarkers of endothelial activation, inflammation and oxidative stress and their relationship with organ dysfunction in human septic shock.
Supervisor of Marisa Oliveira Santos
 Medicina (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2020/09/01 - 2021/05/28 Renal renin-angiotensin system activation in acute heart failure and its association with endothelial dysfunction, inflammation and oxidative stress.
Supervisor of Álvaro Alexandre Ferreira Duarte
 Medicina (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2019/08 - 2020/08 Endocan: a novel biomarker for risk stratification, prognosis, and therapeutic monitoring in human cardiovascular and renal diseases.
Supervisor of João Pedro Peixoto de Bessa e Silva
 Medicina (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2018 - 2019 Gender-related differences in cardiometabolic risk factors and oxidative stress among prepubertal children with obesity
Co-supervisor of Nelson André Oliveira Godinho
 Mestrado Integrado em Medicina (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2016 - 2017 Aspirin and blood pressure: effects when used alone or in combination with antihypertensive drugs.
Supervisor of Ana Catarina Gonçalves da Costa
 Medicina (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2014 - 2015 Statins and oxidative stress in chronic heart failure.
Co-supervisor of Sónia Cristina Torres da Costa
 Medicina (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2013 - 2014/07 Role of semicarbazide-sensitive amine oxidases (SSAO) in the regulation of blood pressure and vascular and renal oxidative stress.
Supervisor of Sofia de Magalhães Lima e Oliveira de Freitas
 Medicina (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2013 - 2014 Resolution of inflammation in heart failure: novel lipid mediators.
Supervisor of Luís Manuel Pedrosa do Vale
 Medicina (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2013 - 2014 Effect of proline supplementation on the development of arterial hypertension and on the production and elimination of hydrogen peroxide - studies in angiotensin II-treated rats
Supervisor of Joana dos Santos Pinto Martins Leal
 Toxicologia Analítica Clínica e Forense (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2012 - 2013 Interaction of aspirin with losartan: impact on inflammation, oxidative stress and lipoxin production in an experimental model of arterial hypertension.
Supervisor of Liliana Raquel Ferraz de Almeida
 Licenciatura em Bioquímica (Degree)
Universidade do Porto Faculdade de Ciências, Portugal
2011/09 - 2012/07 Evaluation of lipoxins in heart failure.
Supervisor of Jorge Daniel Moreira da Silva de Carvalho
 Mestrado em Bioquímica (Master)
Universidade do Porto Faculdade de Ciências, Portugal
2011 - 2012/06 Oxidative stress in heart failure: therapeutic implications.
Co-supervisor of Marco Frederico Oliveira Marques
 Mestrado Integrado em Medicina (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2010 - 2011 Evaluation of NADPH oxidases expression in heart failure.
Supervisor of Isabel Helena da Silva Ribeiro
 Licenciatura em Bioquímica (Degree)
Universidade do Porto Faculdade de Ciências, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2016 - 2016 Member of the Organising Committee of XLVI Reunião da Sociedade Portuguesa de Farmacologia, 2016, FMUP, Porto, Portugal. (2016 - 2016)
Congress (Member of the Organising Committee)
 Universidade do Porto Faculdade de Medicina, Portugal
1997 - 1997 Member of the Organising Committee of the Congress Depressão e antidepressivos - Uma questão de nervos, 1997, Seminário de Vilar, Porto, Portugal. (1997 - 1997)
Congress (Member of the Organising Committee)
 Universidade do Porto Faculdade de Farmácia, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2023/09/25 - 2023/09/25 Chair, Seminar "Renin-angiotensin-aldosterone system in health and disease: new insights into a classic system"
Seminar
 Seminar "Renin-angiotensin-aldosterone system in health and disease: new insights into a classic system"
Universidade do Porto Faculdade de Farmácia, Portugal
2023/04 - 2023/04 Science communication - Presentation entitled: ""Medical doctor scientists @FMUP: the experience of medical students in the research of new therapeutic targets in cardiovascular and infectious diseases"
Exhibition
 20ª Mostra da Universidade do Porto
Universidade do Porto, Portugal
2023/02 - 2023/02 Chair, Session 19 - Cardiovascular Pharmacology, LIII Meeting of the Portuguese Society of Pharmacology
Congress
Sociedade Portuguesa de Farmacologia, Portugal
2022/02 - 2022/02 Chair, Session 4 - Cardiovascular Pharmacology, LII Meeting of the Portuguese Society of Pharmacology
Congress
 LII Meeting of the Portuguese Society of Pharmacology
Sociedade Portuguesa de Farmacologia, Portugal
2021/02 - 2021/02 Chair, Session Clinical Pharmacology III, LI Meeting of the Portuguese Society of Pharmacology
Congress
Sociedade Portuguesa de Farmacologia, Portugal
2016/05 - 2016/05 Speaker, Round Table: "Evaluation of the Doctoral Programmes of the Faculty of Medicine, University of Porto (FMUP)", 5th Meeting of PhD Students from FMUP
Meeting
 5th Meeting of PhD Students from FMUP
Universidade do Porto Faculdade de Medicina, Portugal
2016/02 - 2016/02 Chair, Session 8 - Endocrine Pharmacology, XLVI Meeting of the Portuguese Society of Pharmacology
Congress
Sociedade Portuguesa de Farmacologia, Portugal
2011/02 - 2011/02 Chair, Toxicology Session, XLI Meeting of the Portuguese Society of Pharmacology
Congress
Sociedade Portuguesa de Farmacologia, Portugal
2010/09 - 2010/09 Chair, 3rd Panel, 6th Edition of the School of Life and Health Sciences (ECVS), Junior University, University of Porto
Congress
Universidade do Porto, Portugal

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2023/10/09 Efficacy of Deep Brain Stimulation (DBS) for the Treatment of Dystonia in Cerebral Palsy Patients - A Metanalysis.
(Thesis) Arguer
 Nicole Pedroarena Leal (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2023/03/24 Hydroxytyrosol and hypertension associated with chronic intermittent hypoxia: impact and contribution of AhR alternative pathway
(Thesis) Main arguer
 Maria João Andrade Correia (PhD)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2021/05/25 Sodium-Glucose Cotransporter 2 Inhibitors in Heart Failure - a review.
President of the jury
 Diogo Antunes da Silva Marques (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2021/05/13 Improving Medication Adherence In Hypertensive Patients: A Scoping Review.
President of the jury
 Simão Alves Pinho (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2020/05/25 O papel da reserva cognitiva na infeção pelo VIH.
President of the jury
 Ana Isabel Pestana Lopes (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2020/05/25 FGF23 effects within the vasculature: more insights into Atherosclerosis?
President of the jury
 Maria Inês Coelho Fernandes (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2019/12 Estrategias de tratamiento del paciente com insuficiencia cardiaca sistólica agudamente descompensada: Efectos de frequentes dosis de furosemida sobre los noveles séricos de urea y sobre el cociente urea/creatinina.
(Thesis) Arguer
 Rafael Ramón Villegas Mendez (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2019/03/08 Investigating the role of the mercapturate pathway in kidney function for the identification of an early indicator tubular dysfunction
(Thesis) Main arguer
 CLARA LÚCIA GONÇALVES DIAS (PhD)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2019 Effect of tetrahydrocannabinol on COMT activity in mice prefrontal cortex
(Thesis) Main arguer
 Ana Catarina Relvas do Novo (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2012 Aliscireno: Farmacologia e Interesse Terapêutico.
(Thesis) Main arguer
 Bruno Filipe Leite Pinheiro (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2011/05 The effect of oxidative stress in the intestinal absorption of folic acid: in vitro studies with Caco-2 cells.
(Thesis) Main arguer
 Mafalda Raquel dos Santos Couto (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2011 Osteoporose - Bifosfonatos.
(Thesis) Main arguer
 Paula Joana Fernandes Gomes (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2011 Vitamina D: o lado mais benéfico da exposição à radiação UV.
(Thesis) Main arguer
 Cláudia Fernandes Domingues (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2011 Utilização de bifosfonatos no tratamento da osteoporose pós-menopáusica.
(Thesis) Main arguer
 Carla Sofia Fernandes Correia (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2011 Fatores de risco cardiovascular: Hipertensão Arterial.
(Thesis) Main arguer
 Tânia Isabel Gonçalves Matos (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2011 Perturbação de Hiperatividade com Défice de Atenção.
(Thesis) Main arguer
 Magali Correia do Lago (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2010 Asma: Intervenção Farmacêutica.
(Thesis) Main arguer
 Cristina Magalhães Dias (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2010 Tratamento da artrite reumatóide em adultos.
(Thesis) Main arguer
 Sandra Maria Pinto de Brito Novo (Master)
Universidade do Porto Faculdade de Farmácia, Portugal

Ad Hoc journal article review

Journal title (ISSN) Publisher
2024/05 - 2024/09 Frontiers in Immunology (1664-3224 (Online)) FRONTIERS MEDIA SA
2023 - 2023 Frontiers in Nutrition (2296-861X) FRONTIERS MEDIA SA
2021 - 2021 Frontiers in Pharmacology FRONTIERS MEDIA SA
2018 - 2021 Life Sciences (0024-3205) PERGAMON-ELSEVIER SCIENCE LTD
2019 - 2019 Nitric Oxide-Biology and Chemistry (1089-8603) ACADEMIC PRESS INC ELSEVIER SCIENCE
2019 - 2019 Acta Reumatologica Portuguesa (0303-464X) PUBLISAUDE-EDICOES MEDICAS LDA
2016 - 2019 Cardiology Journal (1897-5593) VIA MEDICA
2018 - 2018 Pediatric Nephrology (0931-041X) SPRINGER
2016 - 2016 PeerJ (2167-8359) PEERJ INC
2013 - 2013 International Journal of Nanomedicine (1178-2013) DOVE MEDICAL PRESS LTD
2007 - 2008 Journal of Enzyme Inhibition and Medicinal Chemistry (1475-6366) TAYLOR & FRANCIS LTD

Association member

Society Organization name Role
2022/05 - Current Ordem dos Farmacêuticos Member
2002 - Current Sociedade Portuguesa de Farmacologia Effective Member
2000 - Current Sociedade Portuguesa de Neurociências Effective Member

Committee member

Activity description
Role 		Institution / Organization
2017/02 - 2019/02 Secretary of the General Assembly of the Portuguese Society of Pharmacology
Other
 Sociedade Portuguesa de Farmacologia, Portugal

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2021/09/01 - Current Neuronal Excitability and Neurotransmission [Module Director] Neurobiologia Universidade do Porto Faculdade de Medicina, Portugal
2021/09 - Current Pharmacology of Synaptic Transmission [Module Director] Neurociências Universidade do Porto Faculdade de Medicina, Portugal
2021/05 - Current Redox state: diet, metabolic regulation and aging. "Oxidative stress: implications for blood pressure". Metabolismo ¿ Biopatologia e Experimentação Universidade do Porto Faculdade de Medicina, Portugal
2020/02 - Current Methods in Neurosciences: Pharmacological approaches. Neurociências Universidade do Porto Faculdade de Medicina, Portugal
2020/02 - Current In vivo methods in Pharmacology: "Animal models of cardiovascular disease" Farmacologia e Toxicologia Experimentais e Clínicas Universidade do Porto Faculdade de Medicina, Portugal
2019 - Current Neuronal Excitability and Neurotransmission: "General Pharmacology I: Pharmacodynamics and general mechanisms of drug action. Types of receptors: GPCRs and signalling pathways." Neurobiologia (Mestrado) Universidade do Porto Faculdade de Medicina, Portugal
2017 - Current Pharmacology of Synaptic Transmission: "Neurotransmission and neuromodulation. Adrenergic transmission." Neurociências (Doutoramento) Universidade do Porto Faculdade de Medicina, Portugal
2017 - Current Neuronal Excitability and Neuromodulation: "Neurotransmission and neuromodulation. Adrenergic transmission." Neurobiologia (Mestrado integrado) Universidade do Porto Faculdade de Medicina, Portugal
2015 - Current In vivo methods in Pharmacology: "Animal models of cardiovascular disease" Farmacologia e Toxicologia Experimentais e Clínicas (Doutoramento) Universidade do Porto Faculdade de Medicina, Portugal
2013 - Current Methods in Neurosciences: Pharmacological Approaches Neurociências (Doutoramento) Universidade do Porto Faculdade de Medicina, Portugal
2010 - Current Free Radicals, Oxidative stress and Antioxidants: Oxidative Stress and Arterial Hypertension. Metabolismo - Clínica e Experimentação (Doutoramento) Universidade do Porto Faculdade de Medicina, Portugal
2008 - 2020 Pharmacology I Medicina (Mestrado integrado) Universidade do Porto Faculdade de Medicina, Portugal
2008 - 2020 Pharmacology II Medicina (Mestrado integrado) Universidade do Porto Faculdade de Medicina, Portugal
2012 - 2012 Postgraduate Course in Pharmaceutical Care: Osteoporosis Curso de pós-graduação em Cuidados Farmacêuticos (Pós-Graduação) Ordem dos Farmaceuticos, Portugal
2008 - 2012 Pharmacology II Ciências Farmacêuticas (Mestrado integrado) Universidade do Porto Faculdade de Farmácia, Portugal
2010 - 2011 Pharmacology I Ciências Farmacêuticas (Mestrado integrado) Universidade do Porto Faculdade de Farmácia, Portugal
2007 - 2008 Pathophysiology and Pharmacotherapy I Ciências Farmacêuticas (Mestrado integrado) Universidade do Porto Faculdade de Farmácia, Portugal
2006 - 2007 Pharmacology I Ciências Farmacêuticas (Licenciatura) Universidade do Porto Faculdade de Farmácia, Portugal
2006 - 2007 Pathophysiology and Pharmacotherapy II Ciências Farmacêuticas (Licenciatura) Universidade do Porto Faculdade de Farmácia, Portugal
2003 - 2004 Pharmacology Ciências Farmacêuticas (Licenciatura) Instituto Universitário de Ciências da Saúde, Portugal
2002 - 2004 Pharmacology Medicina Dentária (Licenciatura) Instituto Universitário de Ciências da Saúde, Portugal

Evaluation committee

Activity description
Role 		Institution / Organization Funding entity
2022/03/01 - 2022/03/31 External Reviewer - Research Grant Proposal - Medical Research Council (MRC)-UK Research and Innovation (UKRI)
Evaluator
 UK Research and Innovation, United Kingdom UK Research and Innovation
2015 - 2015 External reviewer for the 2nd Call for Proposals of the International Fellowship Programme WHRI-ACADEMY (FP7 Marie Curie COFUND scheme)
Evaluator
 Barts and The London School of Medicine and Dentistry William Harvey Research Institute, United Kingdom European Commission Seventh Framework Programme for Research and Technological Development People

Mentoring / Tutoring

Topic Student name
2023/07/03 - 2023/07/28 IFMSA SCORE Research Exchange of International Medical Students - project: "Urinary hydrogen peroxide and its relation to the activity of proinflammatory/prooxidant or antioxidant enzyme activities in intensive care patients: focus on COVID-19 patients. Vesna Bukovec
2023/07/03 - 2023/07/28 IFMSA SCORE Research Exchange of International Medical Students - project: "Urinary hydrogen peroxide and its relation to the activity of proinflammatory/prooxidant or antioxidant enzyme activities in intensive care patients: focus on COVID-19 patients. Alifya Tarwandi
2020/04 - 2022/06 Doctorate Researcher - project RIFF-HEART (PTDC/MEC-CAR/32188/2017) Patrícia Daniela Pereira Terra
2021/08 - 2021/11 Research fellowship (BI) - project RIFF-HEART (PTDC/MEC-CAR/32188/2017) Luísa Alexandra Teixeira Santos
2019/03 - 2020/09 Research fellowship (BI) - project RIFF-HEART (PTDC/MEC-CAR/32188/2017) Carolina Isabel Ribeiro Silva Pereira
2019/06 - 2019/09 Doctorate Researcher - project RIFF-HEART (PTDC/MEC-CAR/32188/2017) Janete Maria Quelhas dos Santos
2017 - 2018 Project I - Urinary excretion of angiotensinogen and hydrogen peroxide in human acute heart failure Rita Pereira Rodrigues da Cruz
2013 - 2015 Research Fellowship (BI) - project OBIKID (PTDC/DTP-PIC/0239/2012) Dina Alexandra Cosme Figueiredo
2012 - 2014 Research fellowship (BI) - project: PTDC/SAU-TOX/114166/2009 Jorge Daniel Moreira da Silva de Carvalho
2011/04 - 2012 Research fellowship (BI) - project: PTDC/SAU-TOX/114166/2009 Maria João Portugal Couto Valente

Other jury / evaluation

Activity description Institution / Organization
2023/05 - 2023/05 Jury, Health Sciences Poster Session, IJUP 2023 (Meeting of Young Researchers of Universidade do Porto, 2023), Universidade do Porto, 2023 Universidade do Porto, Portugal
2022/09/12 - 2022/09/12 Interview meeting - PhD Student: Mariana Ferreira Duarte - Project "Exploring The Ras-Independent Roles of ACE2 as New Biomarkers in Inflammatory Bowel Disease", Doctoral Programme in Experimental and Clinical Pharmacology and Toxicology Universidade do Porto Faculdade de Medicina, Portugal
2021/06 - 2021/06 President of the jury of the call for the attribution of a Research Fellowship (BI) within the scope of the research project "Resolving inflammation: a key to improving the treatment and prognosis of acute heart failure? (RIFF-HEART)" (PTDC/MEC-CAR/32188/2017), funded by FEDER funds via COMPETE (Portugal 2020) and national funds by the FCT. Universidade do Porto Faculdade de Medicina, Portugal
2021/05/05 - 2021/05/07 Jury, Health Sciences e-Poster Session, IJUP 2021 (Meeting of Young Researchers of Universidade do Porto, 2021), Virtual Session, Universidade do Porto, 2021 Universidade do Porto, Portugal
2019/12 - 2020/01 President of the jury of the call for recruitment of a Doctorate Researcher within the scope of the research project "Resolving inflammation: a key to improving the treatment and prognosis of acute heart failure? (RIFF-HEART)" (PTDC/MEC-CAR/32188/2017), funded by FEDER funds via COMPETE (Portugal 2020) and national funds by the FCT. Universidade do Porto Faculdade de Medicina, Portugal
2019/03 - 2019/04 President of the jury of the call for the recruiment of a Doctorate Researcher within the scope of the research project "Resolving inflammation: a key to improving the treatment and prognosis of acute heart failure? (RIFF-HEART)" (PTDC/MEC-CAR/32188/2017), funded by FEDER funds via COMPETE (Portugal 2020) and national funds by the FCT. Universidade do Porto Faculdade de Medicina, Portugal
2018/11 - 2019/02 President of the jury of the call for the attribution of a Research Fellowship (BI) within the scope of the research project "Resolving inflammation: a key to improving the treatment and prognosis of acute heart failure? (RIFF-HEART)" (PTDC/MEC-CAR/32188/2017), funded by FEDER funds via COMPETE (Portugal 2020) and national funds by the FCT. Universidade do Porto Faculdade de Medicina, Portugal
2019 - 2019 Jury, Poster session, IJUP 2019 (Meeting of Young Researchers of Universidade do Porto, 2019), Reitoria da Universidade do Porto, Porto, Portugal. Universidade do Porto, Portugal
2019 - 2019 Jury, Poster session, 11th Symposium on Metabolism - Ageing & Metabolism, FMUP, Porto, Portugal. Universidade do Porto Faculdade de Medicina, Portugal
2018 - 2018 Evaluator of the Final Report entitled "Reactivity of the mesenteric artery to angiotensin II and hydrogen peroxide in an experimental model of inflammatory bowel disease", developed within the scope of the discipline Project I by the student Melani Adão Sousa, Integrated Master in Pharmaceutical Sciences, FFUP. Universidade do Porto Faculdade de Farmácia, Portugal
2017 - 2017 Jury, Poster session, IJUP 2017 (Meeting of Young Researchers of Universidade do Porto, 2017), FMUP, Porto, Portugal. Universidade do Porto Faculdade de Medicina, Portugal
2017 - 2017 Evaluator of the Final Report entitled "Effect of the perivascular adipose tissue on mesenteric artery response to hydrogen peroxide", developed within the scope of the discipline Project I, by the student Paula Cristina de Jesus Gomes, Integrated Master in Pharmaceutical Sciences, FFUP. Universidade do Porto Faculdade de Farmácia, Portugal
2016 - 2016 Evaluator of the Final Report entitled "Vascular reactivity of the mesenteric artery and vein to vasoconstrictors and vasodilators: influence of gender", developed within the scope of the discipline Project I by the student Marta Sofia Gonçalves da Silva, Integrated Master in Pharmaceutical Sciences, FFUP. Universidade do Porto Faculdade de Farmácia, Portugal
2013 - 2013 President of the jury of the call for the attribution of a Research Fellowship (BI) within the scope of the project "Interaction of aspirin with antihypertensive drugs: impact on blood pressure control and oxidative stress, inflammation and activation of the renal renin-angiotensin system" (PTDC/SAU-TOX/114166/2009), funded by FEDER via COMPETE and national funds by FCT. Universidade do Porto Faculdade de Medicina, Portugal
2013 - 2013 Member of the jury of the call for the attribution of a Research fellowship (BI) within the scope of the project "Inflammation and vascular injury in childhood obesity" (PTDC/DTP-PIC/0239/2012), funded by FEDER funds via COMPETE and by national funds by the FCT. Universidade do Porto Faculdade de Medicina, Portugal
2011 - 2011 Member of the jury of the call for the attribution of a Research Fellowship (BI) within the scope of the project "Hypertension and painful neuropathy in diabetes. Role of angiotensin II and oxidative stress in central nervous system" (PTDC/SAU-NEU/101090/2008), funded by FEDER funds via COMPETE and national funds by FCT. Universidade do Porto Faculdade de Medicina, Portugal
2011 - 2011 President of the jury of the call for the attribution of a Research Fellowship (BI) within the scope of the project "Interaction of aspirin with antihypertensive drugs: impact on blood pressure control and oxidative stress, inflammation and activation of the renal renin-angiotensin system" (PTDC/SAU-TOX/114166/2009), funded by FEDER funds via COMPETE and national funds by FCT. Universidade do Porto Faculdade de Medicina, Portugal
2009 - 2009 Member of the jury of the call for the attribution of a Research Fellowship (BI) within the scope of the project "Adenosine-angiotensin II interactions and glomerular injury in Diabetes associated with Hypertension: a new target with therapeutic interest?" (PTDC/SAL/FCF-67764 /2006), funded by FEDER funds via COMPETE and national funds by the FCT. Universidade do Porto Faculdade de Medicina, Portugal
2009 - 2009 Evaluator of the Final Report entitled "Isolation and culture of glomerular mesangial cells and their morphological characterization", developed within the scope of the discipline Project I by the student Catarina Alexandra da Silva Chaves, Integrated Master in Pharmaceutical Sciences, FFUP. Universidade do Porto Faculdade de Farmácia, Portugal
2007 - 2007 Member of the jury of the call for the attribution of a Research Fellowship (BI) within the scope of the project "Adenosine-angiotensin II interactions and glomerular injury in Diabetes associated with Hypertension: a new target with therapeutic interest?" (PTDC/SAL/FCF-67764 /2006), funded by FEDER funds via COMPETE and national funds by FCT. Universidade do Porto Faculdade de Medicina, Portugal
Distinctions

Award

2024 Ambiotis Poster Award (9th European Workshop on Lipid Mediators)
Ambiotis, France
2023 Molecular Biology & Physiology Parallel Oral Session First Prize (18th YES Meeting)
Fundação Professor Ernesto Morais, Portugal
2020 ESCI Short Presentation Award (European Society of Clinical Investigation)
European Society of Clinical Investigation, Netherlands
2019 3rd Prize - Oral Presentation - Plenary Session (14th YES Meeting Scientific Committee)
Fundação AstraZeneca, Portugal
2018 Grant for Young Investigators in Pain -2018 (Fundação Grünenthal)
Fundação Grünenthal, Portugal
2015 Pediatrics Award for studies in other pediatric specialties (Sociedade Portuguesa de Pediatria)
Sociedade Portuguesa de Pediatria, Portugal
2013 Alberto Ferrari Poster Prize (European Society of Hypertension)
European Society of Hypertension, Italy
2007 Young Investigator Prize - Portuguese Society of Hypertension
Sociedade Portuguesa de Hipertensão, Portugal
2002 Lars-Erik Gelin Conference Travel Award (European Society for Microcirculation)
European Society for Microcirculation, United Kingdom
2002 Young Investigator Prize - Gulbenkian Research Stimulus Programme
Fundação Calouste Gulbenkian, Portugal
2001 Poster Award (EPHAR)
3rd Meeting of the Federation of European Pharmacological Societies (EPHAR), France