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Associate Professor of Pharmaceutical Technology and Pharmaceutical Biotechnology and Researcher at FP-I3ID, FP-BHS, Faculty of Health Sciences, University Fernando Pessoa, Porto, Portugal. Senior Researcher at UCIBIO, Faculty of Pharmacy, University of Porto, Portugal. European PhD in Pharmaceutical Sciences with specialization in Pharmaceutical Technology from University of Porto. Graduation in Pharmaceutical Sciences from University Fernando Pessoa. Author of several works in the areas of Pharmaceutical Technology and Pharmaceutical Biotechnology (h-index of 26): >55 articles, 1 book, 6 book chapters, >50 posters, 15 oral communications; editor of 6 books; invited editor of 12 special issues. Included in the World's Top 2% Scientists List, in 2021, 2022, 2023 and 2024, by Stanford University, USA. Member of the editorial board of the Springer book series: Advances in Biochemical Engineering/Biotechnology; Dermatological Drug Delivery from Frontiers in Drug Delivery; Chinese Chemical Letters; Current Drug Metabolism; and Biochemistry & Pharmacology: Open Access. Referee for >10 international funding agencies and >50 journals. Supervisor of 6 FCT funded PhD students (2 completed), 6 MSc students (5 completed), and 37 undergraduate students (34 completed). Current research interests are focused on developing lipid-based nanosystems to improve drug delivery. In particular, nose-to-brain delivery and cutaneous delivery; the quality-by-design (QbD) approach to optimize formulations of lipid-based nanosystems; and the development of Biopharmaceuticals and Advanced Therapy Medicinal Products (ATMPs).
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Identification

Personal identification

Full name
Ana Catarina Silva

Citation names

  • Silva, A. C.

Author identifiers

Ciência ID
5C1D-ED22-0D64
ORCID iD
0000-0001-6923-0232

Websites

Knowledge fields

  • Medical and Health Sciences
  • Medical and Health Sciences - Medical Biotechnology - Health-Related Biotechnology
  • Medical and Health Sciences - Health Sciences

Languages

Language Speaking Reading Writing Listening Peer-review
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Portuguese Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Spanish; Castilian Advanced (C1) Advanced (C1) Intermediate (B1) Advanced (C1)
Affiliation

Science

Category
Host institution 		Employer
2012/10 - Current Researcher (Research) Faculdade de Farmácia, Universidade do Porto, Portugal
2012/09/01 - Current Researcher (Research) Universidade Fernando Pessoa Unidade de Investigação UFP em Energia Ambiente e Saúde, Portugal
2007/06 - 2012/08 Researcher (Research) Universidade do Porto, Portugal

Teaching in Higher Education

Category
Host institution 		Employer
2021/10/01 - Current Associate Professor (University Teacher) Faculdade de Ciências da Saúde, Universidade Fernando Pessoa, Portugal
2016/09 - 2021/09/30 Invited Assistant Professor (University Teacher) Faculdade de Farmácia, Universidade do Porto, Portugal
2012/09 - 2021/09/30 Assistant Professor (University Teacher) Faculdade de Ciências da Saúde, Universidade Fernando Pessoa, Portugal
2010/09 - 2012/09 Assistant (University Teacher) Faculdade de Farmácia, Universidade do Porto, Portugal
2009/09 - 2012/07 Assistant (University Teacher) Faculdade de Ciências da Saúde, Universidade Fernando Pessoa, Portugal

Other Careers

Category
Host institution 		Employer
2006/09 - 2007/08 Técnico Superior (Técnico Superior) Farmácia Campos, Portugal

Positions / Appointments

Category
Host institution 		Employer
2022/06 - Current Conselho para a Qualificação e Admissão (CQA) Ordem dos Farmaceuticos, Portugal
2022/02/22 - Current Primeira Secretária da Assembleia Regional Secção Regional do Norte da Ordem dos Farmacêuticos, Portugal
2019/03/06 - 2022/02/22 Primeira Secretária da Assembleia Regional Secção Regional do Norte da Ordem dos Farmacêuticos, Portugal
Outputs

Publications

Book
  1. Ana Catarina Silva. Biotechnology for Pharmaceutical Sciences. 2024.
    10.1007/978-3-031-60061-6
Book chapter
  1. Silva, A. C.. "Hematopoietic Growth Factors". 2020.
    10.1007/978-3-030-21573-6_72-1
  2. Silva, A. C.. "Hormones, Blood Products, and Therapeutic Enzymes". 2019.
    10_2019_111
  3. Silva, A. C.. "Cytokines and Growth Factors". 2019.
    10.1007/10_2019_105
  4. Silva, A. C.. "Insights on the Formulation of Recombinant Proteins". 2019.
    10.1007/10_2019_119
  5. Silva, A. C.. "Nanopartículas Lipídicas". 2011.
  6. Silva, A. C.. "Advances in Nanoparticulate Carriers for Oral Peptides and Proteins: Polymeric vs. Lipid Nanoparticles". 2011.
Conference abstract
  1. A.C. Correia; I. Costa; R. Silva; J.N. Moreira; J.M. Sousa Lobo; A.C. Silva. "Brain targeting: optimisation and biocompatibility of valproic acid-loaded nanostructured lipid carriers (VPA-NLC) for nose-to-brain delivery". 2023.
    Published
  2. A.C. Correia; J.M. Sousa Lobo; J.N. Moreira; A.C. Silva. "Influence of materials and process parameters on the development of lipid nanoparticles formulations for nose-to-brain drug delivery". Paper presented in 2nd Symposium on Alzheimer’s Disease: An Update on Pathology and Therapeutics, Porto, 2023.
    Published
  3. Torres, Joana; Pereira, José Miguel; Silva, Renata; Oliveira, Rita Marques; Peixoto, Andreia Filipa; Lobo, José Manuel Sousa; Silva, Ana Catarina. "Potential of Antioxidant-Loaded Solid Lipid Nanoparticles (SLN) and Nanostructured Lipid Carriers (NLC) for the Management of Neurodegenerative Diseases". Paper presented in The 8th International Electronic Conference on Medicinal Chemistry, 2022.
    Published • 10.3390/ecmc2022-13417
  4. Pereira, J.M.; Lascasas, I.; Torres, J.; Marques-Oliveira, R.; Peixoto, A.F.; Remião, F.; Sousa Lobo, J.M.; Silva, A. C.; Silva, R.. "Potential neuroprotective effects of astaxanthin-loaded solid lipid nanoparticles (SLN) against oxidative stress". Paper presented in Investigação Jovem na Universidade do Porto (IJUP), 2022.
    Published
  5. Torres, J.; Pereira, J.M.; Silva, R.; Peixoto, A.F.; Sousa Lobo, J.M.; Silva, A. C.. "Potential of astaxanthin-loaded nanostructured lipid carriers (NLC) for the management of neurological diseases,". Paper presented in Investigação Jovem na Universidade do Porto (IJUP), 2022.
    Published
  6. "Development of intranasal carbamazepine-loaded nanostructured lipid carriers (NLC) to improve the treatment of epilepsy". Paper presented in Investigação Jovem na Universidade do Porto (IJUP), 2021.
  7. "Optimization of carbamazepine-loaded nanoemulsions for nose-to-brain delivery". Paper presented in Investigação Jovem na Universidade do Porto (IJUP), 2021.
  8. "Using nanotechnology to prevent skin aging". Paper presented in Investigação Jovem na Universidade do Porto (IJUP), 2021.
  9. "The use of solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) to improve the efficacy of antioxidant molecules in the skin care". Paper presented in Investigação Jovem na Universidade do Porto (IJUP), 2021.
  10. Cunha, Sara; Forbes, Ben; Lobo, José Manuel Sousa; Silva, Ana Catarina. "Thermosensitive Nasal In Situ Gels of Lipid-Based Nanosystems to Improve the Treatment of Alzheimer’s Disease". 2020.
    10.3390/iecp2020-08648
  11. Costa, Cláudia Pina; Cunha, Sara; Peixoto, Andreia F.; Moreira, João Nuno; Lobo, José Manuel Sousa; Silva, Ana Catarina. "Application of the Quality-by-Design (QbD) Approach to Improve the Nose-to-Brain Delivery of Diazepam-Loaded Nanostructured Lipid Carriers (NLCs)". 2020.
    10.3390/iecp2020-08658
  12. Silva, A. C.. "Pessaries containing lipid nanoparticles for vaginal progesterone administration". Paper presented in Investigação Jovem na Universidade do Porto (IJUP), Porto, 2020.
    Published
  13. Oliveira, N.A.; Silva, A. C.; Sousa Lobo, José M.; Amaral, M.H.. "Study of the influence of sterilization and isotonic agents addition on the physicochemical properties of hydrogels sensitive to external stimuli". Paper presented in Investigação Jovem na Universidade do Porto (IJUP), Porto, 2019.
    Published
  14. Cunha, S.; Costa, C.; Amaral, M.H.; Lobo, J.M. Sousa; Silva, A. C.. "Development of nanostructured lipid carriers (NLC) for nose-to-brain delivery by simple quality by design (QbD) approach". Paper presented in XII Spanish-Portuguese Conference on Controlled Drug Delivery, Coimbra, 2018.
    Published
  15. Xavier, C.; Oliveira, N.; Silva, A. C.; Lobo, J.M. Sousa; Amaral, M.H.. "Evaluation of the rheological and texture characteristics of hydrogels composed of stimuli-responsive polymers,". Paper presented in Investigação Jovem na Universidade do Porto (IJUP), Porto, 2018.
    Published
  16. Silva, A. C.; Amaral, M.H.; Eiras, F.; Cunha, S.; Martins, E.; Silva, R.; Sousa Lobo, J.M.. "Biocompatibility of cutaneous formulations containing lipid nanoparticles". Paper presented in 6th FIP Pharmaceutical Sciences World Congress 2017, Stockholm, 2017.
    Published
  17. Cunha, S.; Silva, A. C.. "Novos sistemas terapêuticos para a administração de fármacos utilizados no tratamento de doenças neurodegenerativas: Alzheimer e Parkinson". Paper presented in Dias da investigação na UFP, Porto, 2017.
    Published
  18. Garcês, A.; Lopes, C.M.; Silva, A. C.. "Sistemas semissólidos à base de nanopartículas lipídicas". Paper presented in Dias da investigação na UFP, Porto, 2017.
    Published
  19. Lopes, C.M.; Garcês, A.; Teixeira, M.I.; Catita, J.A.; Silva, A. C.. "Suitability of Semisolid Formulations to Increase Lipid Nanoparticles Consistency for Topical Application". Paper presented in 4th Congress on Innovation in Drug Delivery, Antibes-Juan-les-Pins, 2016.
    Published
  20. Mendes, A.I.; Silva, A. C.; Catita, J.A.; Cerqueira, F.; Lopes, C.M.. "Evaluation of antifungal activity of miconazole-loaded nanostructured lipid carriers (NLC) formulations for oral mucosal administration". Paper presented in Nanoscience and Nanotechnology International Conference, Porto, 2013.
    Published
  21. Sá, A.; Ferreira, D.; Sousa-Lobo, J.M.; Silva, A. C.. "Solid lipid nanoparticles (SLN) for Miconazole encapsulation: preparation, in vitro release and long-term stability studies". Paper presented in Investigação Jovem na Universidade do Porto (IJUP), Porto, 2012.
    Published
  22. Silva, A. C.; Lopes, C.M.; González-Mira, E.; García, M.L.; Egea, M.A.; Santos, D.; Ferreira, D.. "Long-term stability of poor water-soluble drug-loaded solid lipid nanoparticles (SLN)". Paper presented in Colloids and Nanomedicine, Amsterdam, 2012.
    Published
  23. Silva, A. C.; Lopes, C.M.; Santos, D.; Ferreira, D.; Kumar, A.; Wild, W.; Forbes, B.. "Solid lipid nanoparticles (SLN) for oral delivery of poorly water soluble drugs: modeling release profile and drug uptake studies". Paper presented in AAPS Annual Meeting and Exposition, Chicago, 2012.
    Published
  24. Fonseca, J.; Vilas Boas, V.; Sousa-Lobo, J.M.; Ferreira, D.; Silva, A. C.. "Biocompatibility of antipsychotic loaded solid lipid nanoparticles (SLN) for oral delivery". Paper presented in Investigação Jovem na Universidade do Porto (IJUP), Porto, 2011.
    Published
  25. Gomes, C.; Sousa-Lobo, J.M.; Ferreira, D.; Silva, A. C.. "Incorporation of colloidal lipid carriers in semi-solid formulations for topical drug delivery". Paper presented in Investigação Jovem na Universidade do Porto (IJUP), Porto, 2011.
    Published
  26. Silva, A. C.; Lopes, C.M.; Santos, D.; Souto, E.B.; Ferreira, D.. "Antipsychotic-loaded solid lipid nanoparticles (SLN) for oral delivery: modeling release profile". Paper presented in 3rd PharmSciFair, Prague, 2011.
    Published
  27. Silva, A. C.; González-Mira, E.; Egea, M.A.; García, M.L.; Santos, D.; Ferreira, D.; Souto, E.B.. "Preparation of antipsychotic-loaded Solid Lipid Nanoparticles (SLN): high pressure homogenization versus ultrasounds". Paper presented in 7th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Valletta, 2010.
    Published
  28. Gomes, C.; Sousa-Lobo, J.M.; Ferreira, D.; Silva, A. C.. "Solid Lipid Nanoparticles (SLN) – based hydrogel for oral delivery of drugs". Paper presented in 2nd Conference Innovation in Drug Delivery, From preformulation to development through innovative evaluation process, Aix-en-Provence, 2010.
    Published
  29. Silva, A. C.; Lopes, C.M.; Santos, D.; Ferreira, D.; Souto, E.B.. "Nanostructured lipid carriers (NLC)-based hydrogel formulation for topical delivery of minoxidil". Paper presented in Skin and Formulation, 3rd Symposium and Skin Forum, 10th Annual Meeting, Versailles, 2009.
    Published
  30. Silva, A. C.; González-Mira, E.; Egea, M.A.; García, M.L.; Santos, D.; Ferreira, D.; Souto, E.B.. "Phospholipid-coated solid lipid nanoparticles (SLN): Novel approach in Risperidone oral delivery". Paper presented in Symposium on Phospholipids in Pharmaceutical Research, Heidelberg, 2009.
    Published
  31. Silva, A. C.; González-Mira, E.; Egea, M.A.; García, M.L.; Santos, D.; Ferreira, D.; Souto, E.B.. "Characterization of antipsychotic-loaded Solid Lipid Nanoparticles (SLN) prepared by ultrasound technique". Paper presented in AAPS Annual Meeting and Exposition, Los Angeles, California, 2009.
    Published
  32. Silva, A. C.; Gonzalez-Mira, E.; Egea M. A.; Garcia M. L.; Santos, D.; Ferreira, D. C.; Souto, E.B.. "Phospholipid-coated SLN: Novel approach in Risperidone oral delivery". Paper presented in Symposium on Phospholipids in Pharmaceutical Research, Heidelberg, 2009.
    Published
  33. Silva, A. C.; Gonzalez-Mira, E.; Egea M. A.; Garcia M. L.; Pontes, A.; Santos, D.; Ferreira, D. C.; Souto, Eliana Maria Barbosa. "Characterization of Risperidone-loaded Solid Lipid Nanoparticles (SLN) prepared by ultrassound technique". Los Angeles, California, 2009.
  34. Silva, A. C.; Santos, D.; Ferreira, D.; Souto, E.B.; Silva, A. C.. "Assessment of suitability of solid lipid nanoparticles (SLN) for incorporation of Miconazole". Paper presented in CRS, Nova York, 2008.
    Published
  35. Silva, A. C.; Santos, D.; Ferreira, D.; Souto, E.B.. "Preparation of minoxidil-loaded nanostructured lipid carriers (NLC)". Paper presented in 7th Conference and Workshop on Biological Barriers and Nanomedicine – Advanced Drug Delivery and Predictive non vivo Testing Technologies, Saarbrücken, 2008.
    Published
  36. Silva, A. C.; Santos, D.; Ferreira, D.; Souto, E.B.. "Solid lipid nanoparticles as carriers for oral delivery of peptides and proteins - State of the Art". Paper presented in 4th International Intensive course and workshop: Nanomedicines - Nanoparticulates for Drug Delivery, Patras, 2008.
    Published
  37. Silva, A. C.; Santos, D.; Ferreira, D.; Souto, E.B.. "Solid lipid nanoparticles (SLN) – based hydrogel formulation for topical delivery of ibuprofen". Paper presented in 3rd Pharmaceutical Sciences World Congress (PSWC), Amsterdam, 2007.
    Published
  38. Silva, A. C.; Santos, D.; Ferreira, D.; Souto, E.B.. "Incorporation of poorly soluble drugs in bioadhesive lipid nanoparticles". Paper presented in 8th Advanced Summer Course in Cell-Materials Interactions - inflammation in tissue repair and regeneration, Porto, 2007.
    Published
  39. Silva, A. C.; Martins, S.; Ferreira, D.; Souto, E.B.; Sarmento, B.. "Characterization of Calcitonin loaded Solid Lipid Nanoparticles produced by a novel w/o/w emulsion procedure". Paper presented in 13th European Congress on Biotechnology, Barcelona, 2007.
    Published
  40. Souto, E.B.; Silva, A. C.; Santos, D.; Ferreira, D.. "Rheological dynamic experiments performed on lipid-based colloidal carriers for topical pharmaceutics". Paper presented in AAPS Annual Meeting and Exposition, San Diego, California, 2007.
    Published
  41. Silva, A. C.; Santos, D.; Ferreira, D.; Souto, E.B.. "Semi-solid formulations composed of hydroalcoholic gels for topical drug delivery by means of colloidal lipid carriers". Paper presented in AAPS Annual Meeting and Exposition, Santo Antonio, Texas, 2006.
    Published
Conference paper
  1. Costa, C.P.; Nodilo, L.N.; Kalogjera, L; Moreira, J.N.; Sousa Lobo, J.M.; Hafner, A.; Silva, A.C.. "Evaluation of the deposition of an in situ hydrogel containing diazepam loaded nanostructured lipid carriers (NLC) in a 3D nasal cavity model". Paper presented in 13th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Roterdão, 2022.
    Published
  2. Silva, A. C.. "Lipid nanoparticles for vaginal delivery of progesterone". Paper presented in 12th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Vienna, 2021.
    Published
  3. Silva, A. C.. "Optimization of lipid nanoparticles formulation for nose-to-brain delivery using the quality by design (QbD) approach". Paper presented in 12th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Vienna, 2021.
    Published
  4. Silva, A. C.. "Application of the quality-by-design (QbD) approach to improve the nose-to-brain delivery of diazepam-loaded nanostructured lipid carriers (NLC)". Paper presented in 1st International Electronic Conference on Pharmaceutics, 2020.
    Published
  5. Cunha, Sara; Forbes, Ben; Sousa Lobo, José; Silva, Ana. "Thermosensitive nasal in situ gels of lipid-based nanosystems to improve the treatment of Alzheimer's disease". Paper presented in 1st International Electronic Conference on Pharmaceutics, 2020.
    10.3390/iecp2020-08648
  6. Martins, A.C.; Amaral, M.H.; Silva, A. C.; Sousa-Lobo, J.M.. "Estudo comparativo da eficácia hidratante de hidrogéis contendo vectores lipídicos nanoestruturados com esqualeno e óleo de argão". Paper presented in IV Congreso Iberoamericano de Peloides, Caldes de Boi, 2015.
    Published
  7. Silva, A. C.; Tichota, D.; Sousa-Lobo, J.M.; Amaral, M.H.. "Argan oil loaded nanostructured lipid carriers (NLC) for improve skin hydration". Paper presented in 9th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Lisboa, 2014.
    Published
  8. Silva, A. C.; Amaral, M.H.; González-Mira, E.; Santos, D.; Ferreira, D.. "Solid Lipid Nanoparticles (SLN) - based hydrogels for transmucosal delivery of antypsichotics". Paper presented in 8th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Istanbul, 2012.
    Published
  9. Calpena, A.C.; Silva, A. C.; González-Mira, E.; Fernández, F.; Fernández, M.; Flórez, P.; Nikolic, S.. "Solid Lipid Nanoparticles (SLN) for transmucosal sublingual delivery of antipsychotic drug". Paper presented in 8th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Istanbul, 2012.
    Published
  10. González-Mira, E.; Silva, A. C.; Egea, M.A.; García, M.L.; Calpena, A.C.. "Improved skin delivery of flurbiprofen by NLC and NLC-based hydrogels". Paper presented in 8th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Istanbul, 2012.
    Published
  11. Silva, A. C.; Santos, D.; Souto, E.B.; Ferreira, D.. "Phospholipid-coated antipsychotic-loaded Solid Lipid Nanoparticles (SLN) for oral delivery". Paper presented in 9th Spanish-Portuguese Conference on Controlled Drug Delivery and 3rd Congress of the Portuguese Society of Pharmaceutical Sciences, Porto, 2011.
    Published
  12. Silva, A. C.; Lopes, C.M.; González-Mira, E.; Egea, M.A.; García, M.L.; Santos, D.; Ferreira, D.; Souto, E.B.. "Phospholipid-coated solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) for drug delivery". Paper presented in 15th International Pharmaceutical Technology Symposium, Antalya, 2010.
    Published
  13. Silva, A. C.; Amaral, M.H.; Gomes, C.; Santos, D.; Ferreira, D.; Souto, E.B.. "Hydrogel-based solid lipid nanoparticles (SLN) for oral delivery of drugs". Paper presented in 18th International Conference on Bioencapsulation, Porto, 2010.
    Published
  14. Silva, A. C.; González-Mira, E.; Egea, M.A.; García, M.L.; Santos, D.; Ferreira, D.; Souto, E.B.. "Ultrasound preparation of antipsychotic-loaded Solid Lipid Nanoparticles (SLN)". Paper presented in 17th International Conference on Bioencapsulation, Groningen, 2009.
    Published
  15. Silva, A. C.; Santos, D.; Ferreira, D.; Souto, E.B.. "Nanostructured lipid carriers (NLC) as potential carriers for topical delivery of minoxidil". Paper presented in 15th International Workshop on Bioencapsulation & COST 865 meeting, Viena, 2007.
    Published
  16. Silva, A. C.; Ferreira, D.; Souto, E.B.. "Oral delivery of drugs by means of lipid nanoparticles". Paper presented in 14th International Workshop on Bioencapsulation & COST 865 meeting, Lausanne, 2006.
    Published
Conference poster
  1. Torres, J.; Pereira, J.M.; Marques-Oliveira, R.; Correia, C.; Silva, R.; Lobo, J.M. Sousa; Silva, A.C.. "Astaxanthin-loaded nanostructured lipid carriers (NLC) for nose-to-brain delivery in the management of neurodegenerative diseases". Paper presented in 4th European Conference on Pharmaceutics, 2023.
  2. Correia, A.C.; Monteiro, A.R.; Silva, R.; Moreira, J.N.; Lobo, José Manuel Sousa; Silva, A.C.. "Lipid nanoparticles as vehicles for nose-to-brain drug delivery: a strategy to modify pharmacokinetics of drugs targeted to the central nervous system". Paper presented in 4th European Conference on Pharmaceutics, 2023.
  3. Torres, J.; Pereira, J.M.; Costa, I.; Marques-Oveira, R.; Silva, R.; Peixoto, A.F.; Lobo, J.M. Sousa; Silva, A.C.. "Astaxanthin-loaded lipid nanoparticles for nose-to-brain delivery: potential in the management of neurodegenerative diseases". Paper presented in 2nd Symposium on Alzheimer’s Disease: An Update on Pathology and Therapeutics, 2023.
  4. A.C. Correia; J.N. Moreira; J.M. Sousa Lobo; A.C. Silva. "Influence of materials and process parameters on the development of lipid nanoparticles formulations for nose-to-brain drug delivery". 2023.
  5. Torres, J.; Peixoto, A.F.; Silva, R.; Lobo, J.M. Sousa; Silva, A. C.. "Preliminary studies on scaling up the production of lipid nanoparticles by ultrasonication technique". Paper presented in 4th SPLC-CRS Young Scientists Meeting, 2023.
  6. Correia, A.C.; Lobo, J.M. Sousa; Moreia, J.N.; Silva, A.C.. "Pre-formulation studies on the development of valproic acid (VPA)-loaded nanostructured lipid carriers (NLC)". Paper presented in 4th SPLC-CRS Young Scientists Meeting, 2023.
  7. Torres, J.; Pereira, J.M.; Silva, R.; Peixoto, A.F.; Sousa Lobo, J.M.; Silva, A. C.. Corresponding author: Silva, A. C.. "Potential of antioxidant-loaded solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) for the management of neurodegenerative diseases". Paper presented in 8th International Electronic Conference on Medicinal Chemistry, 2022.
  8. Pereira, J.M.; Lascasas, I.; Torres, J.; Marques-Oliveira, R.; Peixoto, AF.; Remião, F.; Sousa Lobo, J.M.; Silva, A. C.; Silva, R.. "Potential neuroprotective effects of astaxanthin-loaded solid lipid nanoparticles (SLN) against oxidative stress". Paper presented in Investigação Jovem na Universidade do Porto (IJUP), 2022.
  9. Costa, C.P.; Nodilo, L.N.; Kalogjera, L.; Moreira, J.N.; Sousa Lobo, J.M.; Hafner, A.; Silva, A. C.. "Evaluation of the deposition of an in situ hydrogel containing diazepam loaded nanostructured lipid carriers (NLC) in a 3D nasal cavity model". Paper presented in 13th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 2022.
  10. "Development of intranasal carbamazepine-loaded nanostructured lipid carriers (NLC) to improve the treatment of epilepsy". Paper presented in Investigação Jovem na Universidade do Porto (IJUP), 2021.
  11. "Optimization of lipid nanoparticles formulation for nose-to-brain delivery using the quality by design (QbD) approach". Paper presented in 12th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 2021.
  12. Correia A.; Costa, C.P.; Silva, R.; Silva, V.; Sousa Lobo, J.M.; Silva, A. C.. "Lipid nanoparticles for vaginal delivery of progesterone". Paper presented in 12th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 2021.
  13. "Optimization of carbamazepine-loaded nanoemulsions for nose-to-brain delivery". Paper presented in Investigação Jovem na Universidade do Porto (IJUP), 2021.
  14. Silva, A. C.. "Thermosensitive nasal in situ hydrogel of nanostructured lipid carriers (NLC) to improve the treatment of Alzheimer's Disease". Paper presented in 3rd SPLC-CRS Young Scientists Meeting, 2021.
  15. Silva, A. C.. "Using the Quality-by-Design (QbD) approach for the optimization of critical process parameters (CPPs) of diazepam-loaded nanostructured lipid carriers (NLC)". Paper presented in 3rd SPLC-CRS Young Scientists Meeting, 2021.
  16. Silva, A. C.. "Pessaries with progesterone-loaded nanostructured lipid carriers (NLC) for prolonged release". Paper presented in Virtual Vancouver Nanomedicine Day, 2020.
  17. Silva, A. C.. "Optimization of diazepam-loaded nanostructured lipid carriers (NLC) for nose-to-brain delivery using the quality by design (QbD) approach". Paper presented in Virtual Vancouver Nanomedicine Day, 2020.
  18. Silva, A. C.. "Hydrogel formulations containing nanostructured lipid carriers (NLC) and nanoemulsions (NE) for intranasal delivery of carbamazepine". Paper presented in 1st Annual Meeting in Pharmaceutical Sciences, 2019.
  19. Silva, A. C.. "Characterization and biometric evaluation of an o/w emulsion containing nanostructured lipid carriers: A pilot study". Paper presented in International Federation of Societies of Cosmetic Chemists, 2019.
  20. Silva, A. C.. "In vitro and human in vivo evaluation of the skin hydration potential of vitamin E-loaded lipid nanosystems formulations". Paper presented in Controlled Release Society Annual Meeting & Exposition, 2019.
  21. Silva, A. C.. "Development of a semi-solid formulation for the intranasal delivery of carbamazepine by means of lipid-based nanosystems". Paper presented in Controlled Release Society Annual Meeting & Exposition, 2019.
  22. Silva, A. C.. "Optimization of nanostructured lipid carriers (NLC) for nose-to-brain delivery using Quality by Design (QbD) approach". Paper presented in Controlled Release Society Annual Meeting & Exposition, 2019.
  23. Silva, A. C.. "Study of the influence of sterilization and isotonic agents addition on the physicochemical properties of hydrogels sensitive to external stimuli". Paper presented in Investigação Jovem na Universidade do Porto (IJUP), 2019.
  24. Vaz, S.; Silva, R.; Amaral, M.H.; Martins, E.; Sousa Lobo, José M.; Silva, A. C.. "Biocompatibility and skin hydration potential of vitamin E-loaded lipid nanosystems formulations". Paper presented in Investigação Jovem na Universidade do Porto (IJUP), 2019.
  25. Silva, A. C.. "Evaluation of the rheological and texture characteristics of hydrogels composed of stimuli-responsive polymers". Paper presented in Investigação Jovem na Universidade do Porto (IJUP), 2018.
  26. Silva, A. C.. "Development of nanostructured lipid carriers (NLC) for nose-to-brain delivery by simple quality by design (QbD) approach". Paper presented in XII Spanish-Portuguese Conference on Controlled Drug Delivery, 2018.
  27. Silva, A. C.. "Biocompatibility of cutaneous formulations containing lipid nanoparticles". Paper presented in 6th FIP Pharmaceutical Sciences World Congress, 2017.
  28. Silva, A. C.. "Suitability of Semisolid Formulations to Increase Lipid Nanoparticles Consistency for Topical Application". Paper presented in 4th Congress on Innovation in Drug Delivery, 2016.
  29. Silva, A. C.. "Estudo comparativo da eficácia hidratante de hidrogéis contendo vectores lipídicos nanoestruturados com esqualeno e óleo de argão". Paper presented in IV Congresso Iberoamericano de Peloides (CIPAB), 2015.
  30. Silva, A. C.. "Evaluation of antifungal activity of miconazole-loaded nanostructured lipid carriers (NLC) formulations for oral mucosal administration". Paper presented in Nanoscience and Nanotechnology International Conference, 2013.
  31. Silva, A. C.. "Solid lipid nanoparticles (SLN) for oral delivery of poorly water soluble drugs: modeling release profile and drug uptake studies". Paper presented in AAPS Annual Meeting and Exposition, 2012.
  32. Silva, A. C.. "Long-term stability of poor water-soluble drug-loaded solid lipid nanoparticles (SLN)". Paper presented in Colloids and Nanomedicine, 2012.
  33. Silva, A. C.. "Solid lipid nanoparticles (SLN) for Miconazole encapsulation: preparation, in vitro release and long-term stability studies". Paper presented in Investigação Jovem na Universidade do Porto (IJUP), 2012.
  34. Silva, A. C.. "Antipsychotic-loaded solid lipid nanoparticles (SLN) for oral delivery: modelling release profile". Paper presented in 3rd PharmSciFair, 2011.
  35. Silva, A. C.. "Incorporation of colloidal lipid carriers in semi-solid formulations for topical drug delivery". Paper presented in Investigação Jovem na Universidade do Porto (IJUP), 2011.
  36. Silva, A. C.. "Biocompatibility of antipsychotic loaded solid lipid nanoparticles (SLN) for oral delivery". Paper presented in Investigação Jovem na Universidade do Porto (IJUP), 2011.
  37. Silva, A. C.. "Solid Lipid Nanoparticles (SLN) – based hydrogel for oral delivery of drugs". Paper presented in 2nd Conference Innovation in Drug Delivery, From preformulation to development through innovative evaluation process, 2010.
  38. Silva, A. C.. "Characterization of antipsychotic-loaded Solid Lipid Nanoparticles (SLN) prepared by ultrasound technique". Paper presented in AAPS Annual Meeting and Exposition, 2009.
  39. Silva, A. C.. "Phospholipid-coated solid lipid nanoparticles (SLN): Novel approach in Risperidone oral delivery". Paper presented in 1st Symposium on Phospholipids in Pharmaceutical Research, 2009.
  40. Silva, A. C.. "Nanostructured lipid carriers (NLC)-based hydrogel formulation for topical delivery of minoxidil". Paper presented in Skin and Formulation, 3rd Symposium and Skin Forum, 10th Annual Meeting, 2009.
  41. Silva, A. C.. "Solid lipid nanoparticles as carriers for oral delivery of peptides and proteins - State of the Art". Paper presented in 4th International Intensive course and workshop: Nanomedicines - Nanoparticulates for Drug Delivery, 2008.
  42. Silva, A. C.. "Preparation of minoxidil-loaded nanostructured lipid carriers (NLC)". Paper presented in 7th Conference and Workshop on Biological Barriers and Nanomedicine – Advanced Drug Delivery and Predictive non vivo Testing Technologies, 2008.
  43. Silva, A. C.. "Rheological dynamic experiments performed on lipid-based colloidal carriers for topical pharmaceutics". Paper presented in AAPS Annual Meeting and Exposition, 2007.
  44. Silva, A. C.. "Effectiveness of oral insulin delivery by means of solid lipid nanoparticles". Paper presented in 43rd EASD Annual Meeting, 2007.
  45. Silva, A. C.. "Characterization of Calcitonin loaded Solid Lipid Nanoparticles produced by a novel w/o/w emulsion procedure". Paper presented in 13th European Congress on Biotechnology, 2007.
  46. Silva, A. C.. "Characterization of ibuprofen loaded solid lipid nanoparticles dispersed in semi-solid Carbopol gels". Paper presented in 13th European Congress on Biotechnology, 2007.
  47. Silva, A. C.. "Incorporation of poorly soluble drugs in bioadhesive lipid nanoparticles". Paper presented in 8th Advanced Summer Course in Cell-Materials Interactions - inflammation in tissue repair and regeneration, 2007.
  48. Silva, A. C.. "Solid lipid nanoparticles (SLN) – based hydrogel formulation for topical delivery of ibuprofen". Paper presented in 3rd Pharmaceutical Sciences World Congress (PSWC), 2007.
  49. Silva, A. C.. "Semi-solid formulations composed of hydroalcoholic gels for topical drug delivery by means of colloidal lipid carriers". Paper presented in AAPS Annual Meeting and Exposition, 2006.
Edited book
  1. A.C. Silva. Springer Handbook of Medical Biotechnology. Springer Nature. 2024.
    Accepted • Editor
  2. A.C. Silva; J.M. Sousa Lobo; D. Ferreira. Part I - Biologicals, in: Springer Handbook of Biomedical Biotechnology. Springer Nature. 2024.
    Accepted • Editor
  3. A.C. Silva; J.N. Moreira; F. Andon. Part II - Innovative Therapies, in: Springer Handbook of Biomedical Biotechnology. Springer Nature. 2024.
    Accepted • Editor
  4. Silva, A. C.; Moreira, J.N.; Sousa Lobo, J.M.. Current Insights on Lipid-Based Nanosystems. MDPI. 2023.
    Published • 10.3390/books978-3-0365-6165-3
  5. Almeida, H.; Silva, A.C.. Nanoparticles in Ocular Drug Delivery Systems. 2023.
    Published
  6. A.C. Silva; J.N. Moreira; J.M. Sousa Lobo. Current Insights on Lipid-Based Nanosystems 2023. MDPI. 2023.
    Published • 10.3390/books978-3-0365-9805-5
  7. Silva, A. C.; Sousa Lobo, J.M.. Preclinical Evaluation of Lipid-Based Nanosystems. MDPI. 2021.
    10.3390/books978-3-0365-1549-6
  8. Silva, A. C.. Current Applications of Pharmaceutical Biotechnology. 2020.
    10.1007/978-3-030-40464-2
Journal article
  1. Silva, Ana Catarina; Moreira, João Nuno; Sousa Lobo, José Manuel. "Current Insights on Lipid-Based Nanosystems 2023". Pharmaceuticals 16 12 (2023): 1700. http://dx.doi.org/10.3390/ph16121700.
    Published • 10.3390/ph16121700
  2. Correia, A.C.; Moreira, J.N.; Sousa Lobo, J.M.; Silva, A.C.. "Design of experiment (DoE) as a quality by design (QbD) tool to optimise formulations of lipid nanoparticles for nose-to-brain drug delivery". Expert Opinion on Drug Delivery 20 12 (2023): 1731-1748. http://dx.doi.org/10.1080/17425247.2023.2274902.
    10.1080/17425247.2023.2274902
  3. Pina Costa, Cláudia; Nižic Nodilo, Laura; Silva, Renata; Martins, Eva; Zadravec, Dijana; Kalogjera, Livije; Nuno Moreira, João; et al. "In situ hydrogel containing diazepam-loaded nanostructured lipid carriers (DZP-NLC) for nose-to-brain delivery: development, characterization and deposition studies in a 3D-printed human nasal cavity model". International Journal of Pharmaceutics 644 (2023): 123345. http://dx.doi.org/10.1016/j.ijpharm.2023.123345.
    10.1016/j.ijpharm.2023.123345
  4. Torres, J.; Peixoto, A.F.; Silva, R.; Lobo, J.M. Sousa; Silva, A.C.. Corresponding author: Silva, A.C.. "Uso intranasal de nanopartículas lipídicas contendo compostos antioxidantes provenientes de bio-resíduos marinhos e o seu potencial no tratamento de doenças neurodegenerativas". Acta Farmacêutica Portuguesa 12 1 (2023): 16-50. https://actafarmaceuticaportuguesa.com/index.php/afp/article/view/358.
    Published
  5. Almeida, Hugo; Silva, Ana Catarina. "Nanoparticles in Ocular Drug Delivery Systems". Pharmaceutics 15 6 (2023): 1675. http://dx.doi.org/10.3390/pharmaceutics15061675.
    10.3390/pharmaceutics15061675
  6. Torres, Joana; Pereira, José Miguel; Marques-Oliveira, Rita; Costa, Inês; Gil-Martins, Eva; Silva, Renata; Remião, Fernando; et al. "An In Vitro Evaluation of the Potential Neuroprotective Effects of Intranasal Lipid Nanoparticles Containing Astaxanthin Obtained from Different Sources: Comparative Studies". Pharmaceutics 15 4 (2023): 1035. http://dx.doi.org/10.3390/pharmaceutics15041035.
    10.3390/pharmaceutics15041035
  7. Torres, Joana; Costa, Inês; Peixoto, Andreia F.; Silva, Renata; Sousa Lobo, José Manuel; Silva, Ana Catarina. "Intranasal Lipid Nanoparticles Containing Bioactive Compounds Obtained from Marine Sources to Manage Neurodegenerative Diseases". Pharmaceuticals 16 2 (2023): 311. http://dx.doi.org/10.3390/ph16020311.
    10.3390/ph16020311
  8. Shastri, Divyesh H.; Silva, Ana Catarina; Almeida, Hugo. "Ocular Delivery of Therapeutic Proteins: A Review". Pharmaceutics 15 1 (2023): 205. http://dx.doi.org/10.3390/pharmaceutics15010205.
    10.3390/pharmaceutics15010205
  9. Ana Catarina Silva. "Editorial—Current Insights on Lipid-Based Nanosystems". Pharmaceuticals 15 10 (2022): 1267-1267. http://dx.doi.org/10.3390/ph15101267.
    10.3390/ph15101267
  10. Ana Catarina Silva. "Lipid nanoparticles strategies to modify pharmacokinetics of central nervous system targeting drugs: Crossing or circumventing the blood–brain barrier (BBB) to manage neurological disorders". Advanced Drug Delivery Reviews 189 (2022): 114485-114485. http://dx.doi.org/10.1016/j.addr.2022.114485.
    10.1016/j.addr.2022.114485
  11. Cunha, S.; Swedrowska, M.; Bellahnid, Y.; Xu, Z.; Sousa Lobo, J.M.; Forbes, Ben; Silva, A.C.. "Thermosensitive in situ hydrogels of rivastigmine-loaded lipid-based nanosystems for nose-to-brain delivery: characterisation, biocompatibility, and drug deposition studies". International Journal of Pharmaceutics 620 (2022): 121720. http://dx.doi.org/10.1016/j.ijpharm.2022.121720.
    10.1016/j.ijpharm.2022.121720
  12. Pereira, Adriana; Ramalho, Maria João; Silva, Renata; Silva, Vera; Marques-Oliveira, Rita; Silva, Ana Catarina; Pereira, Maria Carmo; Loureiro, Joana A.. "Vine Cane Compounds to Prevent Skin Cells Aging through Solid Lipid Nanoparticles". Pharmaceutics 14 2 (2022): 240. http://dx.doi.org/10.3390/pharmaceutics14020240.
    Open access • Published • 10.3390/pharmaceutics14020240
  13. Catarina Gonçalves; Maria João Ramalho; Renata Silva; Vera Silva; Rita Marques-Oliveira; Ana Catarina Silva; Maria Carmo Pereira; Joana A. Loureiro. "Lipid Nanoparticles Containing Mixtures of Antioxidants to Improve Skin Care and Cancer Prevention". Pharmaceutics (2021): https://doi.org/10.3390/pharmaceutics13122042.
    10.3390/pharmaceutics13122042
  14. Cláudia Pina Costa; Sandra Barreiro; João Nuno Moreira; Renata Silva; Hugo Almeida; José Manuel Sousa Lobo; Ana Catarina Silva. "In Vitro Studies on Nasal Formulations of Nanostructured Lipid Carriers (NLC) and Solid Lipid Nanoparticles (SLN)". Pharmaceuticals 14 8 (2021): 711-711. https://doi.org/10.3390/ph14080711.
    10.3390/ph14080711
  15. H. Almeida; A.C. Silva; M.H. Amaral; P. Lobao; J.M. Sousa Lobo. "Preparações oftálmicas: novas estratégias para a promoção da biodisponibilidade". Acta Pharmaceutica Portuguesa 10 1 (2021): 44-83. https://www.actafarmaceuticaportuguesa.com/index.php/afp/article/view/237/220.
    Published
  16. Silva, A. C.. "Quality by design (QbD) optimization of diazepam-loaded nanostructured lipid carriers (NLC) for nose-to-brain delivery: toxicological effect of surface charge on human neuronal cells". International Journal of Pharmaceutics (2021): 120933-120933. http://dx.doi.org/10.1016/j.ijpharm.2021.120933.
    10.1016/j.ijpharm.2021.120933
  17. Sara Cunha; Ben Forbes; José Manuel Sousa Lobo; Ana Catarina Silva. "Improving Drug Delivery for Alzheimer’s Disease Through Nose-to-Brain Delivery Using Nanoemulsions, Nanostructured Lipid Carriers (NLC) and in situ Hydrogels". International Journal of Nanomedicine (2021): https://doi.org/10.2147/IJN.S305851.
    10.2147/IJN.S305851
  18. Ana Catarina Silva; José Manuel Sousa Lobo. "Preclinical Evaluation of Lipid-Based Nanosystems". Pharmaceutics 13 5 (2021): 708-708. https://doi.org/10.3390/pharmaceutics13050708.
    10.3390/pharmaceutics13050708
  19. Silva, A. C.. "Intranasal delivery of nanostructured lipid carriers, solid lipid nanoparticles and nanoemulsions: A current overview of in vivo studies". Acta Pharmaceutica Sinica B (2021): https://authors.elsevier.com/tracking/article/details.do?aid=1010&jid=APSB&surname=Silva.
    Published • 10.1016/j.apsb.2021.02.012
  20. Silva, A. C.. "Medicamentos biológicos - Exemplos aprovados em Portugal". Acta Farmacêutica Portuguesa 9 2 (2020): 36-62. https://www.actafarmaceuticaportuguesa.com/index.php/afp/article/view/221/213.
    Published
  21. Sara Cunha; Ben Forbes; José Manuel Sousa Lobo; Ana Catarina Silva. "Thermosensitive Nasal In Situ Gels of Lipid-Based Nanosystems to Improve the Treatment of Alzheimer’s Disease". Proceedings (2020): https://doi.org/10.3390/IECP2020-08648.
    10.3390/IECP2020-08648
  22. Cláudia Pina Costa; Sara Cunha; Andreia F. Peixoto; João Nuno Moreira; José Manuel Sousa Lobo; Ana Catarina Silva. "Application of the Quality-by-Design (QbD) Approach to Improve the Nose-to-Brain Delivery of Diazepam-Loaded Nanostructured Lipid Carriers (NLCs)". Proceedings (2020): https://doi.org/10.3390/IECP2020-08658.
    10.3390/IECP2020-08658
  23. Silva, A. C.. "Preparações Vaginais: Ontem, Hoje e Amanhã". Revista Portuguesa de Farmacoterapia (2020): http://revista.farmacoterapia.pt/index.php/rpf/article/view/299/266.
    10.25756/rpf.v12i3.249
  24. A. Correia; C.P. Costa; V. Silva; R. Silva; J.M. Sousa Lobo; A.C. Silva. "Pessaries containing nanostructured lipid carriers (NLC) for prolonged vaginal delivery of progesterone". European Journal of Pharmaceutical Sciences 153 (2020): 105475-105475. https://doi.org/10.1016/j.ejps.2020.105475.
    10.1016/j.ejps.2020.105475
  25. Sara Cunha; Cláudia Pina Costa; Joana A. Loureiro; Jorge Alves; Andreia F. Peixoto; Ben Forbes; José Manuel Sousa Lobo; Ana Catarina Silva. "Double Optimization of Rivastigmine-Loaded Nanostructured Lipid Carriers (NLC) for Nose-to-Brain Delivery Using the Quality by Design (QbD) Approach: Formulation Variables and Instrumental Parameters". Pharmaceutics 12 7 (2020): 599-599. https://doi.org/10.3390/pharmaceutics12070599.
    10.3390/pharmaceutics12070599
  26. Cátia Gomes; Ana Catarina Silva; Ana Camila Marques; José Sousa Lobo; Maria Helena Amaral. "Biotechnology Applied to Cosmetics and Aesthetic Medicines". Cosmetics 7 2 (2020): 33-33. https://doi.org/10.3390/cosmetics7020033.
    10.3390/cosmetics7020033
  27. Silva, A. C.. "Using the quality by design (QbD) approach to optimize formulations of lipid nanoparticles and nanoemulsions: A review". Nanomedicine: Nanotechnology, Biology and Medicine (2020):
    https://doi.org/10.1016/j.nano.2020.102206
  28. Silva, A. C.. "Corrigendum to “Evaluation of the biocompatibility and skin hydration potential of vitamin E-loaded lipid nanosystems formulations: In vitro and human in vivo studies” [Colloid Surfaces B: Biointerfaces 179 (2019) 242–249]". Colloids and Surfaces B: Biointerfaces (2020):
    10.1016/j.colsurfb.2019.110593
  29. Silva, Ana Catarina; Moreira, Joao Nuno; Sousa Lobo, Jose Manuel; Almeida, Hugo. "Current Applications of Pharmaceutical Biotechnology Preface". Advances in Biochemical Engineering/Biotechnology (2020): https://publons.com/wos-op/publon/55327523/.
  30. Silva, A. C.. "Células estaminais na regeneração da pele: aplicações terapêuticas e cosméticas". Acta Farmacêutica Portuguesa (2019):
    Accepted
  31. Silva, A. C.. "Evaluation of the biocompatibility and skin hydration potential of vitamin E-loaded lipid nanosystems formulations: In vitro and human in vivo studies". (2019): http://dx.doi.org/10.1016/j.colsurfb.2019.03.036.
    10.1016/j.colsurfb.2019.03.036
  32. C. Costa; J.N. Moreira; M.H. Amaral; J.M. Sousa Lobo; A.C. Silva. "Nose-to-brain delivery of lipid-based nanosystems for epileptic seizures and anxiety crisis". Journal of Controlled Release 295 (2019): 187-200. https://doi.org/10.1016/j.jconrel.2018.12.049.
    10.1016/j.jconrel.2018.12.049
  33. Silva, Ana Catarina; Amaral, Maria Helena; Sousa Lobo, Jose Manuel; Almeida, Hugo. "Editorial: Applications of Solid Lipid Nanoparticles (SLN) and Nanostructured Lipid Carriers (NLC): State of the Art". Current Pharmaceutical Design 23 43 (2018): 6551-6552. http://dx.doi.org/10.2174/138161282343180215151302.
    10.2174/138161282343180215151302
  34. Garcês, A.; Amaral, M.H.; Lobo, J.M. Sousa; Silva, A. C.. "Formulations based on solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) for cutaneous use: A review". European Journal of Pharmaceutical Sciences 112 (2018): 159-167.
    Published • 10.1016/j.ejps.2017.11.023
  35. Santos, S.; Silva, A. C.. "Medicamentos biossimilares - aplicação no tratamento do cancro". Acta Farmacêutica Portuguesa 7 1 (2018): 3-22.
    Published
  36. Santos, Sofia B.; Sousa Lobo, José M.; Silva, Ana C.. "Biosimilar medicines used for cancer therapy in Europe: a review". Drug Discovery Today 0 (2018): 0-0.
    Published • 10.1016/j.drudis.2018.09.011
  37. Eiras, F.; Amaral, M.H.; Silva, R.; Martins, E.; Lobo, J.M. Sousa; Silva, A.C.. "Characterization and biocompatibility evaluation of cutaneous formulations containing lipid nanoparticles". International Journal of Pharmaceutics 519 1-2 (2017): 373-380.
    Published • 10.1016/j.ijpharm.2017.01.045
  38. Cunha, S.; Almeida, H.; Amaral, M.H.; Lobo, J.M. Sousa; Silva, A. C.. "Intranasal lipid nanoparticles for the treatment of neurodegenerative diseases". Current Pharmaceutical Design 23 (2017): 1-10.
    Published • 10.2174/1381612824666171128105305
  39. Silva, A. C.; Cunha, Sara; Amaral, Maria Helena; Sousa Lobo, José Manuel; Silva, Ana. "Lipid nanoparticles for nasal/intranasal drug delivery". Critical Reviews in Therapeutic Drug Carrier Systems 34 (2017): 257-282. http://dl.begellhouse.com/journals/3667c4ae6e8fd136,forthcoming,18693.html.
    Published • doi: 10.1615/CritRevTherDrugCarrierSyst.2017018693
  40. Silva, Ana Catarina; Amaral, Maria Helena; Sousa Lobo, Jose Manuel; Almeida, Hugo. "Applications of Solid Lipid Nanoparticles (SLN) and Nanostructured Lipid Carriers (NLC): State of the Art". Current Pharmaceutical Design (2017): https://publons.com/wos-op/publon/16993120/.
    10.2174/138161282343180215151302
  41. Cunha, S.; Amaral, M.H.; Sousa Lobo, J.M.; Silva, A.C.. "Therapeutic strategies for Alzheimer's and Parkinson's diseases by means of drug delivery systems". Current Medicinal Chemistry 23 31 (2016): 3618-3631.
    Published • 10.2174/0929867323666160824162401
  42. Moreno, M.; Amaral, M.H.; Sousa Lobo, J.M.; Silva, A.C.. "Scaffolds for bone regeneration: State of the art". Current Pharmaceutical Design 22 18 (2016): 2726-2736. http://www.scopus.com/inward/record.url?eid=2-s2.0-84974686116&partnerID=MN8TOARS.
  43. Silva, Ana; Lopes, Carla; Lobo, Jose; Amaral, Maria. "EDITORIAL (Thematic Issue: Advances in Pharmaceutical Biotechnology)". Current Pharmaceutical Biotechnology 16 11 (2015): 938-939. http://dx.doi.org/10.2174/1389201016999150827103855.
    10.2174/1389201016999150827103855
  44. Silva, A.C.; Lopes, C.M.; Lobo, J.M.S.; Amaral, M.H.. "Delivery systems for biopharmaceuticals. part I: Nanoparticles and microparticles". Current Pharmaceutical Biotechnology 16 11 (2015): 940-954. http://www.scopus.com/inward/record.url?eid=2-s2.0-84942155383&partnerID=MN8TOARS.
  45. Silva, A.C.; Lopes, C.M.; Lobo, J.M.S.; Amaral, M.H.. "Nucleic acids delivery systems: A challenge for pharmaceutical technologists". Current Drug Metabolism 16 1 (2015): 3-16. http://www.scopus.com/inward/record.url?eid=2-s2.0-84937131381&partnerID=MN8TOARS.
  46. Silva, A.C.; Amaral, M.H.; Lobo, J.M.; Lopes, C.M.. "Lipid nanoparticles for the delivery of biopharmaceuticals". Current Pharmaceutical Biotechnology 16 4 (2015): 291-302. http://www.scopus.com/inward/record.url?eid=2-s2.0-84930972194&partnerID=MN8TOARS.
  47. Silva, A.C.; Lopes, C.M.; Lobo, J.M.S.; Amaral, M.H.. "Delivery systems for biopharmaceuticals. part II: Liposomes, micelles, microemulsions and dendrimers". Current Pharmaceutical Biotechnology 16 11 (2015): 955-965. http://www.scopus.com/inward/record.url?eid=2-s2.0-84942096153&partnerID=MN8TOARS.
  48. Almeida, H.; Amaral, M.H.; Lobão, P.; Silva, A.C.; Lobo, J.M.S.. "Applications of polymeric and lipid nanoparticles in ophthalmic pharmaceutical formulations: Present and future considerations". Journal of Pharmacy and Pharmaceutical Sciences 17 3 (2014): 278-293. http://www.scopus.com/inward/record.url?eid=2-s2.0-84904559612&partnerID=MN8TOARS.
  49. Silva, A. C.. "Design, characterization, and clinical evaluation of argan oil nanostructured lipid carriers (NLC) to improve skin hydration". International Journal of Nanomedicine (2014): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000340170500001&KeyUID=WOS:000340170500001.
    10.2147/IJN.S64008
  50. Lopes, Carla; Silva, Ana. "Editorial (Thematic Issue: Therapeutic Applications of Advanced Drug Delivery Systems)". Current Pharmaceutical Design 19 41 (2013): 7167-7168. http://dx.doi.org/10.2174/138161281941131219122506.
    10.2174/138161281941131219122506
  51. Lopes, Carla; Silva, Ana. "Editorial (Thematic Issue: Therapeutic Applications of Advanced Drug Delivery Systems)". Current Pharmaceutical Design 19 41 (2013): 7167-7168. http://dx.doi.org/10.2174/138161281941131219122506.
    10.2174/138161281941131219122506
  52. Mendes, A.I.; Silva, A.C.; Catita, J.A.M.; Cerqueira, F.; Gabriel, C.; Lopes, C.M.. "Miconazole-loaded nanostructured lipid carriers (NLC) for local delivery to the oral mucosa: Improving antifungal activity". Colloids and Surfaces B: Biointerfaces 111 1 (2013): 755-763.
    Published • 10.1016/j.colsurfb.2013.05.041
  53. Silva, A. C.. "Current progresses on nanodelivery systems for the treatment of neuropsychiatric diseases: Alzheimer’s and Schizophrenia". Current Pharmaceutical Design (2013): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000328896700003&KeyUID=WOS:000328896700003.
    10.2174/138161281941131219123329
  54. Silva, A.C.; Kumar, A.; Wild, W.; Ferreira, D.; Santos, D.; Forbes, B.. "Long-term stability, biocompatibility and oral delivery potential of risperidone-loaded solid lipid nanoparticles". International Journal of Pharmaceutics 436 1-2 (2012): 798-805.
    Published • 10.1016/j.ijpharm.2012.07.058
  55. Silva, A.C.; Lopes, C.M.; Fonseca, J.; Soares, M.E.; Santos, D.; Souto, E.B.; Ferreira, D.. "Risperidone Release from Solid Lipid Nanoparticles (SLN): Validated HPLC Method and Modelling Kinetic Profile". Current Pharmaceutical Analysis 8 4 (2012): 307-316.
    Published • 10.2174/157341212803341663
  56. Silva, A.C.; Amaral, M.H.; González-Mira, E.; Santos, D.; Ferreira, D.. "Solid lipid nanoparticles (SLN) - based hydrogels as potential carriers for oral transmucosal delivery of Risperidone: Preparation and characterization studies". Colloids and Surfaces B: Biointerfaces 93 1 (2012): 241-248.
    Published • 10.1016/j.colsurfb.2012.01.014
  57. Silva, A.C.; Santos, D.; Ferreira, D.; Lopes, C.M.. "Lipid-based nanocarriers as an alternative for oral delivery of poorly water-soluble drugs: Peroral and mucosal routes". Current Medicinal Chemistry 19 26 (2012): 4495-4510. http://www.scopus.com/inward/record.url?eid=2-s2.0-84865758788&partnerID=MN8TOARS.
    10.2174/092986712803251584
  58. Silva, A.C.; González-Mira, E.; García, M.L.; Egea, M.A.; Fonseca, J.; Silva, R.; Santos, D.; Souto, E.B.; Ferreira, D.. "Preparation, characterization and biocompatibility studies on risperidone-loaded solid lipid nanoparticles (SLN): High pressure homogenization versus ultrasound". Colloids and Surfaces B: Biointerfaces 86 1 (2011): 158-165.
    Published • 10.1016/j.colsurfb.2011.03.035
  59. Lopes, C.M.; Oliveira, R.; Silva, A.C.. "Pharmaceutical approaches for optimizing oral anti-inflammatory delivery systems". Anti-Inflammatory and Anti-Allergy Agents in Medicinal Chemistry 10 3 (2011): 154-165. http://www.scopus.com/inward/record.url?eid=2-s2.0-79960600852&partnerID=MN8TOARS.
  60. Silva, A. C.. "Phospholipid-coated antipsychotic-loaded Solid Lipid Nanoparticles (SLN) for oral delivery". Revista Portuguesa de Farmácia (2011):
  61. Silva, A. C.; Teixeira, V.; Silva, A. C.; Lopes, C.M.. "The Role of Nanotechnology in Cancer Treatment and Diagnosis". Revista da Faculdade de Ciências da Saúde - Universidade Fernando Pessoa, 7 (2010): 216-224. http://bdigital.ufp.pt/handle/10284/2974.
    Published
  62. Silva, A. C.. "Minoxidil-loaded nanostructured lipid carriers (NLC): characterization and rheological behaviour of topical formulations". Pharmazie (2009): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000264277700006&KeyUID=WOS:000264277700006.
    10.1691/ph.2009.8232
  63. Silva, A. C.; Martins, S.; Silva, A. C.; Ferreira, D.; Souto, E.B.. "Improving oral absorption of Salmon calcitonin by trimyristin lipid nanoparticles". Journal of Biomedical Nanotechnology 5 (2009): 76-83. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000263689500008&KeyUID=WOS:000263689500008.
    Published • 10.1166/jbn.2009.443
  64. Silva, A. C.. "Abstracts 2007: Effectiveness of oral insulin delivery by means of solid lipid nanoparticles". Diabetologia 50 S1 (2007): 1-538. http://dx.doi.org/10.1007/s00125-007-0809-7.
    Published • 10.1007/s00125-007-0809-7
  65. Silva, A. C.; Silva, A. C.; Santos, D.; Ferreira, D.; Souto, E.B.. "Characterization of ibuprofen loaded solid lipid nanoparticles dispersed in semi-solid Carbopol gels". Journal of Biotechnology (2007): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000249687100109&KeyUID=WOS:000249687100109.
    Published • 10.1016/j.jbiotec.2007.07.117
  66. Silva, A.C.; Santos, D.; Ferreira, D.C.; Souto, E.B.. "Oral delivery of drugs by means of solid lipid nanoparticles". Minerva Biotecnologica 19 1 (2007): 1-5. http://www.scopus.com/inward/record.url?eid=2-s2.0-34547879217&partnerID=MN8TOARS.
  67. Sarmento, Bruno; Martins, Susana; Ferreira, Domingos; Souto, Eliana B.; Silva, A. C.; Santos, D.; Ferreira, D. C.; Souto, E. B.. "Oral insulin delivery by means of solid lipid nanoparticles". International Journal of Nanomedicine (2007): https://publons.com/wos-op/publon/13056635/.
Journal issue
  1. Silva, A. C.; Almeida, H.; Barros, A.. "New Challenges in the Cosmetics and Medical Device Industry". Pharmaceutics; Pharmaceuticals; Antioxidants; Nanomaterials; Journal of Functional Biomaterials; Cosmetics (2024): https://www.mdpi.com/topics/1RAC67W74N.
    Accepted • Invited editor
  2. Almeida, H.; Silva, A. C.. "Nanoparticles in Ocular Drug Delivery Systems". Pharmaceutics (2023): https://www.mdpi.com/journal/pharmaceutics/special_issues/ocular_dds.
    Accepted
  3. Ferraz, M.P.; Silva, A. C.. "Feature Review Papers in Materials Science and Engineering". (2023): https://www.mdpi.com/journal/applsci/special_issues/materials_review.
    Accepted
  4. Silva, A. C.; Sousa Lobo, J.M.. "Formulation of Biopharmaceuticals and Advanced Therapy Medicinal Products (ATMPs)". Pharmaceutics (2023): https://www.mdpi.com/journal/pharmaceutics/special_issues/ATMPs.
    Accepted
  5. Silva, A.C.; Moreira, J.N.; Sousa Lobo, J.M.. "Current Insights on Lipid-Based Nanosystems 2023". Pharmaceuticals (2023): https://www.mdpi.com/journal/pharmaceuticals/special_issues/NLC4Y2M84S.
  6. Silva, A. C.. "Current insights on lipid-based nanosystems". Pharmaceuticals (2022): https://www.mdpi.com/journal/pharmaceuticals/special_issues/lipid_based_nanosystems.
    Published • Invited editor
  7. Silva, A. C.; Sousa Lobo, J.M.. "Preclinical Evaluation of Lipid-Based Nanosystems (Volume II)". (2022): https://www.mdpi.com/journal/pharmaceutics/special_issues/preclinical_lipid_nano_II.
    Published
  8. Silva, A. C.. "Preclinical Evaluation of Lipid-Based Nanosystems". MDPI (2021): https://www.mdpi.com/journal/pharmaceutics/special_issues/preclinical_lipid_nano.
    Published • 10.3390/pharmaceutics13050708 • Invited editor
  9. Loureiro J.; Pereira M.C.; Moreno-Gonzalez I.; Silva, A. C.. "Nano-Based Improvements of Bioactive Compound Pharmacological Properties for the Treatment of Alzheimer's Disease and Parkinson's Disease". Frontiers in Bioengineering and Biotechnology (2020):
    Published
  10. Silva, A. C.; Amaral, M.H.; Sousa Lobo, J.M.; Almeida, H.. "Applications of solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC): State of the art". Current Pharmaceutical Design (2018):
    Published • 10.2174/1381612824666171214102607 • Invited editor
  11. Silva, A.C.; Lopes, C.M.; Lobo, J.M.S.; Amaral, M.H.. "Advances in pharmaceutical biotechnology". Current Pharmaceutical Biotechnology 16 11 (2015): https://www.eurekaselect.com/134407/article.
    Published • Invited editor
  12. Silva, A. C.; Lopes, C.M.. "Therapeutic Applications of Advanced Drug Delivery Systems". Current Pharmaceutical Design (2013): https://www.eurekaselect.com/119059.
    Published • 10.2174/138161281941131219122506 • Invited editor
Manual
  1. Silva, A. C.. Farmácia Galénica - Manual de Apoio às Aulas Teóricas. 2022.
    Published
  2. Silva, A. C.. Biotecnologia Industrial Farmacêutica - Manual de Apoio às Aulas Laboratoriais. 2021.
    Published
  3. Silva, A. C.. Biotecnologia Industrial Farmacêutica - Manual de Apoio às Aulas Teóricas. 2021.
    Published
  4. Silva, A. C.. Novos Sistemas Terapêuticos - Manual de Apoio às Aulas Laboratoriais. 2021.
    Published
  5. Silva, A. C.. Novos Sistemas Terapêuticos - Manual de Apoio às Aulas Teóricas. 2021.
    Published
  6. Silva, A. C.. Biotecnologia Industrial Farmacêutica - Manual de Apoio às Aulas Laboratoriais. Portugal. 2020.
    Published
  7. Silva, A. C.. Biotecnologia Industrial Farmacêutica - Manual de Apoio às Aulas Teóricas. Portugal. 2020.
    Published
  8. Silva, A. C.. Novos Sistemas Terapêuticos - Manual de Apoio às Aulas Laboratoriais. Portugal. 2020.
    Published
  9. Silva, A. C.. Novos Sistemas Terapêuticos - Manual de Apoio às Aulas Teóricas. Portugal. 2020.
    Published
  10. Silva, A. C.. Biotecnologia Industrial Farmacêutica - Manual de Apoio às Aulas Laboratoriais. Portugal. 2019.
  11. Silva, A. C.. Biotecnologia Industrial Farmacêutica - Manual de Apoio às Aulas Teóricas. Portugal. 2019.
  12. Silva, A. C.. Novos Sistemas Terapêuticos - Manual de Apoio às Aulas Laboratoriais. Portugal. 2019.
  13. Silva, A. C.. Novos Sistemas Terapêuticos - Manual de Apoio às Aulas Teóricas. Portugal. 2019.
  14. Silva, A. C.. Biotecnologia Industrial Farmacêutica - Manual de Apoio às Aulas Laboratoriais. Portugal. 2018.
  15. Silva, A. C.. Biotecnologia Industrial Farmacêutica - Manual de Apoio às Aulas Teóricas. Portugal. 2018.
  16. Silva, A. C.. Novos Sistemas Terapêuticos - Manual de Apoio às Aulas Laboratoriais. Portugal. 2018.
  17. Silva, A. C.. Biotecnologia Industrial Farmacêutica - Manual de Apoio às Aulas Laboratoriais. 2017.
  18. Silva, A. C.. Biotecnologia Industrial Farmacêutica - Manual de Apoio às Aulas Teóricas. 2017.
  19. Silva, A. C.. Novos Sistemas Terapêuticos - Manual de Apoio às Aulas Laboratoriais. 2017.
  20. Silva, A. C.; Barreira, S.. Biotecnologia Industrial Farmacêutica - Manual de Apoio às Aulas Laboratoriais. Portugal. 2016.
  21. Silva, A. C.. Biotecnologia Industrial Farmacêutica - Manual de Apoio às Aulas Teóricas. Portugal. 2016.
  22. Silva, A. C.. Novos Sistemas Terapêuticos - Manual de Apoio às Aulas Laboratoriais. Portugal. 2016.
  23. Silva, A. C.. Biotecnologia Industrial Farmacêutica - Manual de Apoio às Aulas Teóricas. Portugal. 2015.
  24. Silva, A. C.; Barreira, S.. Biotecnologia Industrial Farmacêutica - Manual de Apoio às Aulas Laboratoriais. Portugal. 2015.
  25. Silva, A. C.; Barreira, S.. Biotecnologia Industrial Farmacêutica - Manual de Apoio às Aulas Laboratoriais. Portugal. 2014.
  26. Silva, A. C.. Biotecnologia Industrial Farmacêutica - Manual de Apoio às Aulas Teóricas. Portugal. 2014.
  27. Lopes, C.M.; Silva, A. C.. Tecnologia dos Injectáveis e Colírios - Manual das Aulas Laboratoriais. Portugal. 2013.
  28. Silva, A. C.; Barreira, S.. Biotecnologia Industrial Farmacêutica - Manual de Apoio às Aulas Laboratoriais. Portugal. 2013.
  29. Silva, A. C.. Biotecnologia Industrial Farmacêutica - Manual de Apoio às Aulas Teóricas. Portugal. 2013.
  30. Costa, P.; Amaral, M.H.; Silva, A. C.; Martins, S.. Tecnologia Farmacêutica III - Manual de Apoio às Aulas Laboratoriais. Portugal. 2012.
  31. Silva, A. C.; Martins, S.; Bahia, F.; Lobão, P.. O Design do Medicamento. Portugal. 2009.
Preface / Postscript
  1. Silva, A. C.; Moreira, J.N.; Sousa Lobo, J.M.; Almeida H.. Corresponding author: Silva, A. C.. "Current Applications of Pharmaceutical Biotechnology". Preface to Advances in Biochemical Engineering/Biotechnology. Springer Netherlands. 2020.
    Published

Other

Other output
  1. Solid Lipid Nanoparticles (SLN) for Oral Delivery of Risperidone. 2012. Silva, A. C..
  2. Promotores de Absorção Cutânea. 2006. Silva, A. C..
Distinctions

Other distinction

2023 World's Top 2% Scientists list
Stanford University, United States
2022 World's Top 2% Scientists list
Stanford University, United States
2021 World's Top 2% Scientists list
Stanford University, United States
2009 Bolsa
Fundação Calouste Gulbenkian - Portugal, Portugal
2009 Bolsa
COST865 2009 Summer School Early Stage Researcher Training on Bioencapsulation - Anzère, Suíça, Portugal
2008 Bolsa
7th Conference and Workshop on Biological Barriers and Nanomedicine – Saarbrücken, Alemanha, Portugal
2008 Bolsa
4th International intensive course: Nanomedicines-Nanoparticulates for drug delivery- Patras, Grécia, Portugal
2007 Bolsa de Doutoramento
Fundação para a Ciência e a Tecnologia (FCT), Portugal
2006 Melhor aluna da licenciatura
Universidade Fernando Pessoa, Portugal