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Joana Carvalho holds a PhD in Biomedicine (Univ. Porto 2012). She was a Post-Doc at the ERiC group at Ipatimup (2013-2018), and a Junior Researcher at i3S (2019-2024). Presently, she is an Assistant Researcher at i3S. Joana graduated in Biochemistry from the University of Coimbra in 2006, after spending one year as an ERASMUS student in Bergen, Norway. After graduating, Joana was a scientific research fellow (BTI) at the Cancer Genetics group at Ipatimup. In 2008, Joana was awarded two short-term fellowships, sponsored by the European Molecular Biology Organization and the Gulbenkian Foundation, to work at the Tumor Profiling Unit at the VuMC, Amsterdam. All these fellowships awarded Joana extensive experience in molecular and cellular biology techniques and were pivotal to the development of her capacity to lead projects independently. During her Ph.D. (2009-2012), Joana worked at Ipatimup, VuMC, and the University of Aveiro under the supervision of Dr. Carla Oliveira and the co-supervision of Dr. Beatriz Carvalho and Dr. Manuel Santos. Joana's PhD thesis highlighted microRNA-mediated mechanisms regulating E-cadherin expression in Gastric Cancer and revealed the impact of somatic CDH1 alterations in the prognosis and survival of Gastric Cancer patients. From 2013 to 2018, as a Post-doc researcher, Joana was particularly devoted to the study of extracellular vesicles in biological processes underlying cancer progression and metastasis and their value as tools to identify molecular signatures to monitor tumor relapse and/or treatment response of Gastric Cancer patients. During this time, Joana became a Member of the management committee of the European Network on Microvesicles and Exosomes on Health and Disease (COST Action BM1202), published together with other members two highly cited review papers, and participated in a European project. Joana is also the co-first author and co-last and corresponding author of original/opinion works on the field of extracellular vesicles. Remarkably, one of her original works was awarded the prestigious Pulido Valente Science 2020 Prize. Joana has also established a collaboration with a cancer hospital (IPOFG-Coimbra) to develop prospective studies with longitudinal and cross-sectional molecular analyses of extracellular vesicles and cell-free circulating tumor DNA isolated from plasma of cancer patients (gastric and colorectal) collected from diagnosis to follow-up. Currently, Joana is interested in studying the crosstalk between cancer cells and the tumor microenvironment. In particular, she aims to dissect how oncogenic signaling affects such interactions, and how this crosstalk impacts disease progression and therapy resistance. To achieve this, she is mainly using organoid technology, animal models, and patient-derived material. During the last years, Joana has participated in twelve scientific projects, funded by distinct agencies and was the PI of one FCT-funded project (2023-2024). Joana supervised one MSc thesis and has been involved in the co-supervision of three PhD students (two ongoing and one completed), one MSc thesis, and several MSc, BSc students and MD trainees. Joana has also received several prizes in national and international conferences, participated as a jury examiner in several Master dissertations, and was a reviewer in peer-reviewed journals. Joana has an h-index of 19 and is a co-author of 32 peer-reviewed articles cited 6,417 times (Scopus total citations- February 2025) and four book chapters.
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Identification

Personal identification

Full name
Joana Teresa Lopes Carvalho

Citation names

  • Carvalho, Joana

Author identifiers

Ciência ID
5D11-3E77-E6AB
ORCID iD
0000-0001-9743-438X
Researcher Id
J-9476-2013
Scopus Author Id
56726810900

Email addresses

  • jcarvalho@i3s.up.pt (Professional)

Addresses

  • Instituto de Patologia e Imunologia Molecular da Universidade do Porto - IPATIMUP. Rua Júlio Amaral de Carvalho 45, 4200-135, Porto, Porto, Portugal (Professional)

Websites

Knowledge fields

  • Medical and Health Sciences - Basic Medicine

Languages

Language Speaking Reading Writing Listening Peer-review
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Spanish; Castilian Intermediate (B1) Intermediate (B1) Elementary (A2) Intermediate (B1)
French Intermediate (B1) Intermediate (B1) Elementary (A2) Intermediate (B1)
Education
Degree Classification
2018
Concluded
 Tissue Engineering Course: from stem cells to organoids (Outros)
Centre for Genomic Regulation, Spain
2016
Concluded
 Laboratory Animal Science – FELASA category C (Outros)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2013
Concluded
 Extracellular vesicles: implications in biomedicine (Outros)
Universidad Internacional Menéndez Pelayo, Spain
2012
Concluded
 Biomedicine (Doutoramento)
Universidade do Porto Faculdade de Medicina, Portugal
"The involvement of microRNAs in Gastric Cancer" (THESIS/DISSERTATION)
 Aprovada com Distinção
2008
Concluded
 mRNA profiling using DNA Microarrays - Molecular Genomics Advanced Course (Outros)
Universidade de Aveiro, Portugal
2006
Concluded
 Bioquímica (Licenciatura)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Analysis of zebrafish Six 3/6 family transcription factors: expression, developmental function and DNA-binding" Anders Fjose " (THESIS/DISSERTATION)
 15
Affiliation

Others

Category
Host institution 		Employer
2025/01/01 - Current Assistant Researcher (2023.08116.CEECIND) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2019/01/01 - 2024/12/31 Junior Researcher (10.54499/DL57/2016/CP1363/CT0012) Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
(...)
2016/08/01 - 2018/12/31 Post-doc fellow [FCT SFRH/BPD/86543/2012] "Circulating Exosomes: a tool to follow gastric tumour dynamics and therapy response" supervised by Carla Oliveira Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2013/03/01 - 2016/07/31 Post-doc fellow [FCT SFRH/BPD/86543/2012] "Study of secreted cell vesicles during epithelial-mesenchymal-epithelial transitions and their role in the cancer metastasis" supervised by Carla Oliveira Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
2009/02/01 - 2012/12/07 PhD student [FCT - SFRH/BD/44074/2008] "The involvement of microRNAs in Gastric Cancer" supervised by Carla Oliveira, Beatriz Carvalho, Manuel A. Santos Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
(...)
2008/11/01 - 2009/01/31 Short term fellowship awarded by European Molecular Biology Organization (EMBO- ASTF 338-2008) VU Medical Center- Tumor Profiling Unit , Netherlands
2008/06/01 - 2008/08/31 Short term fellowship awarded by Fundação Calouste Gulbenkian VU Medical Center- Tumor Profiling Unit , Netherlands
2006/12/01 - 2008/05/31 Research fellow [FCT - POCI/SAL/-OBS/56921/2004] "In mismatch repair deficiency colorectal cancer are BRAF and KRAS new prognostic and therapeutic tools? supervised by Raquel Seruca&Carla Oliveira Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
2005/09/01 - 2006/06/30 Undergraduate research student "Analysis of zebrafish Six 3/6 family transcription factors: expression, developmental function and DNA-binding" supervised by Prof. Anders Jose University of Bergen - Department of Molecular Biology, Norway
Projects

Grant

Designation Funders
2023/01/01 - 2024/12/30 Deconstructing the Cell Communication Routes of mutant KRAS Colorectal Liver to Lung Metastasis: improving patient survival
DOI: 10.54499/2022.05346.PTDC
DOI: 10.54499/2022.05346.PTDC
2022.05346.PTDC
Principal investigator
Fundação para a Ciência e a Tecnologia
Ongoing
2018 - 2022 Solving the unsolved rare diseases: Hereditary Diffuse Gastric Cancer-SolveRD
779257
Researcher
Horizon 2020
Concluded
2018 - 2021 Stroke in translation: Biomarkers for diagnosis and management of acute ischemic stroke
PTDC/MEC-NEU/31674/2017
Post-doc
Fundação para a Ciência e a Tecnologia
Concluded
2018 - 2021 MIStranslation: A novel trigger of genome instability in cancer-MISTIC
PTDC/MED-ONC/28834/2017
Post-doc
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2018 - 2021 Solving the 3D chromatin structure of CDH1 locus to identify disease-associated mechanisms
PTDC/BTM-TEC/30164/2017
Post-doc
Fundação para a Ciência e a Tecnologia
2017 - 2021 Tackling CANcer STEM CELls: a challenge and an opportunity to advance in anti-cancer therapy
POCI-01-0145-FEDER-016390
Post-doc
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2016 - 2019 Advancing cancer research: From Basic knowledge to application - WP3 Tumour secreted factors in EMT/Non-EMT cells for invasion and metastization
NORTE-01- 0145-FEDER-000029
Post-doc
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
Concluded
2016 - 2018 The role of gastric cancer cell-derived extracellular vesicles
GCEV
Co-Principal Investigator (Co-PI)
Universidade do Porto Instituto de Patologia e Imunologia Molecular
Concluded
2015 - 2015 The role of exosomes in EMT/MET and gastric cancer progression
NA
Co-Principal Investigator (Co-PI)
Universidade do Porto Instituto de Patologia e Imunologia Molecular
Concluded
2012/02/01 - 2015 ADHESION, DIFFERENTIATION AND INVASION: DIFFERENT PROCESSES, COMMON CADHERIN PLAYERS
PTDC/SAU-GMG/120049/2010
Post-doc
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2005/07/01 - 2008 In mismatch repair deficiency colorectal cancer are BRAF and KRAS new prognostic and therapeutic tools?
POCI/SAL/-OBS/56921/2004
Research Fellow
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded

Contract

Designation Funders
2017 - 2022 Training in extracelular vesicles: For benefit in health & disease-TRAIN-EV
722148
Post-doc
EU Framework Programme for Research and Innovation Marie Sklodowska-Curie Actions
Concluded
2013 - 2016 Using NGS to uncover structural and regulatory variation in gastric cancer
NGSGC_2013
Post-doc
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
 Coimbra Genomics

BGI Group
Concluded
Outputs

Publications

Book chapter
  1. Mendes, N.; Dias Carvalho, P.; Martins, F.; Mendonça, S.; Malheiro, A. R.; Ribeiro, A.; Carvalho, J.; Velho, S.. "Animal Models to Study Cancer and Its Microenvironment". In Advances in Experimental Medicine and Biology, 389-401. Springer International Publishing, 2020.
    Published • 10.1007/978-3-030-34025-4_20
  2. Leite, M.; Corso, G.; Sousa, S.; Carvalho, J.; Roviello, F.; Oliveira, C.; Figueiredo, C.; Seruca, R.. "Non- CDH1 -associated familial gastric cancer and epigenetics factors". 2013.
    10.1007/978-94-007-6570-2_10
  3. Carvalho, J.; Pinheiro, H.; Oliveira, C.. "Alternative mechanisms to germline CDH1 mutations in hereditary diffuse gastric cancer". 2013.
    10.1007/978-94-007-6570-2_8
  4. Carvalho, J.; Pinheiro, H.; Oliveira, C.. "E-Cadherin germline mutations". 2013.
    10.1007/978-94-007-6570-2_5
Conference abstract
  1. Carvalho, Joana. "P12.089A High level of co-occurrence of moderate risk alleles in the germline of familial intestinal gastric cancer syndrome". Paper presented in 50th European Society of Human Genetics Conference, Copenhagen, 2018.
    Published
  2. Carvalho, Joana. "P17.20D Dies1/VISTA expression loss is a recurrent event in gastric cancer due to epigenetic regulation". Paper presented in 50th European Society of Human Genetics Conference, Copenhagen, 2018.
    Published • 10.1038/s41431-018-0247-7
  3. Carvalho, J; Oliveira, P; Saraiva, N; Rocha, S; Bonito, N; Oliveira, C. "PO-523 Unveiling the microrna signature of gastric cancer exosomes: longitudinal and cross-sectional perspectives". Paper presented in The 25th Biennial Congress of the European Association for Cancer Research, Amsterdam, 2018.
    Published • 10.1136/esmoopen-2018-eacr25.1024
  4. Carvalho, Joana. "OS20.05 The impact of 3D cellular architecture in the microRNA and protein content of extracellular vesicles". Paper presented in International Society of Extracellular Vesicles 2018, Barcelona, 2018.
    Published
  5. Ko, Song Yi; Naora, Honami. "OPW3.2=PF4.01 Gastric cancer cell-derived extracellular vesicles modulate E-cadherin expression, invasion and migration of normal cells from the tumour microenvironment". Paper presented in The Fifth International Meeting of ISEV, ISEV2016, Rotterdam, 2016.
    Published • 10.1158/1538-7445.am2017-783
  6. Carvalho, Joana. "C04.6 Through the looking glass: the reversion of EMT". Paper presented in European Human Genetics Conference 2015, Glasgow, 2015.
    Published
  7. Carvalho, Joana. "P11.121 Somatic alterations of the E-Cadherin gene predict survival of gastric cancer patients mainly those presenting with familial history". Paper presented in European Human Genetics Conference 2013, Paris, 2013.
    Published
  8. Carvalho, Joana. "P11.070 Large rearrangements involving intron 2 of CDH1 and breast cancer susceptibility". Paper presented in European Human Genetics Conference 2013, Paris, 2013.
    Published
  9. Carvalho, Joana. "P06.090** microRNA-101 modulates E-cadherin expression and function through EZH2 up-regulation in gastric cancer". Paper presented in European Human Genetics Conference 2011, Amsterdam, 2011.
    Published
  10. Carvalho, Joana. "P06.071 A novel CDH1 transcript increases gastric cancer cell invasion and angiogenic potential". Paper presented in European Human Genetics Conference 2011, Amsterdam, 2011.
    Published
Conference poster
  1. Carvalho, Joana. "Exploring the role of mutant KRAS in mediating the crosstalk between colorectal cancer cells and fibroblasts: implications for invasion and metastatic potential". Paper presented in III ASPIC-ASEICA International Meeting, 2023.
  2. Carvalho, Joana. "Exploring the role of mutant KRAS in mediating the crosstalk between colorectal cancer cells and fibroblasts: implications for invasion and metastatic potential". Paper presented in Targeting RAS – New Avenues and Challenges, 2023.
  3. Carvalho, Joana. "High level of co-occurrence of moderate risk alleles in the germline of familial intestinal gastric cancer syndrome". Paper presented in 50th European Society of Human Genetics Conference, 2018.
  4. Carvalho, Joana. "Unveiling the microrna signature of gastric cancer exosomes: longitudinal and cross-sectional perspectives". Paper presented in The 25th Biennial Congress of the European Association for Cancer Research, 2018.
  5. Carvalho, Joana. "Gastric Tumour Dynamics and Therapy Response followed by a microRNA Signature of Circulating Exosomes". Paper presented in 3rd ASPIC International Congress, 2018.
  6. Carvalho, Joana. "Co-occurrence of Moderate Risk Alleles in the Germline of Familial Intestinal Gastric Cancer Syndrome". Paper presented in 25th United European Gastroenterology (UEG) Week, 2017.
  7. Carvalho, Joana. "Dissecting the (epi)genetic landscapes of Gastric Cancer: on the road to liquid biopsy". Paper presented in National Symposium of the Portuguese Oncology Society, 2016.
  8. Carvalho, Joana. "Gastric Cancer cell-derived extracellular vesicles modulate E-cadherin expression, invasion and migration of normal cells from the tumor microenvironment". Paper presented in International Society of Extracellular Vesicles 2016, 2016.
  9. Carvalho, Joana. "Extracellular vesicles - shuttles of epithelial and mesenchymal properties". Paper presented in 1st International Congress ASPIC, 2014.
  10. Carvalho, Joana. "Extracellular vesicles - shuttles of epithelial to mesenchymal to epithelial transitions". Paper presented in II GEIVEX SYMPOSIUM, 2014.
  11. Carvalho, Joana. "Extracellular vesicles - shuttles of epithelial to mesenchymal to epithelial transitions". Paper presented in 4th I3S Annual Meeting, 2014.
  12. Carvalho, Joana. "Somatic alterations of the E-Cadherin Gene Predict Survival of Gastric Cancer Patients mainly those presenting with familial history". Paper presented in European Human Genetics Conference 2013, 2013.
  13. Carvalho, Joana. "Somatic alterations of the E-Cadherin gene predict survival of gastric cancer patients mainly those presenting with familial history". Paper presented in European Human Genetics Conference 2013, 2013.
  14. Carvalho, Joana. "Lack of microRNA-101 causes E-cadherin functional deregulation through EZH2 up-regulation in intestinal gastric cancer". Paper presented in 22nd Biennial Congress of the European Association for Cancer Research, 2012.
  15. Carvalho, Joana. "Somatic mutations and deletions of the E-Cadherin Gene Predict Poor Survival of Patients with Gastric Cancer". Paper presented in One Day Symposium with Keynote Speaker Carlos Caldas, EACR, 2012.
  16. Carvalho, Joana. "Regulation of the E-cadherin-Catenin Complex by MicroRNAs in Gastric Cancer". Paper presented in I3S Scientific Retreat, 2011.
  17. Carvalho, Joana. "MicroRNA-101 Modulates E-cadherin Expression and Function Through EZH2 Up-regulation in Gastric Cancer". Paper presented in European Human Genetics Conference 2011, 2011.
  18. Carvalho, Joana. "MicroRNA-101 Modulates E-cadherin Expression and Function Through EZH2 Up-regulation in Gastric Cancer". Paper presented in Mechanism and Biology of Silencing (C7) – Keystone Symposia, 2011.
  19. Carvalho, Joana. "microRNA-101 modulates E-cadherin expression and function through EZH2 up-regulation in gastric cancer". Paper presented in European Human Genetics Conference 2011, 2011.
  20. Carvalho, Joana. "MicroRNA-101 is a modulator of E-cadherin impairment in Gastric Cancer". Paper presented in XIX Porto Cancer Meeting, 2010.
  21. Carvalho, Joana. "MicroRNA-101 is a modulator of E-cadherin impairment in Gastric Cancer". Paper presented in I3S Scientific Retreat, 2010.
  22. Carvalho, Joana. "The NMD mRNA surveillance pathway downregulates aberrant E-cadherin transcripts in gastric cancer cells and in CDH1 mutation carriers". Paper presented in IV National RNA Meeting, 2007.
  23. Carvalho, Joana. "The NMD mRNA surveillance pathway downregulates aberrant E-cadherin transcripts in gastric cancer cells and in CDH1 mutation carriers". Paper presented in XI Meeting of the Portuguese Society of Human Genetics, 2007.
Journal article
  1. Susana Mendonça Oliveira; Patrícia Dias Carvalho; André Serra-Roma; Patrícia Oliveira; Andreia Ribeiro; Joana Carvalho; Flávia Martins; et al. "Fibroblasts Promote Resistance to KRAS Silencing in Colorectal Cancer Cells". Cancers (2024): https://doi.org/10.3390/cancers16142595.
    10.3390/cancers16142595
  2. Maqueda, Joaquín J.; Giovanazzi, Alberta; Rocha, Ana Mafalda; Rocha, Sara; Silva, Isabel; Saraiva, Nadine; Bonito, Nuno; et al. "Adapter dimer contamination in sRNA-sequencing datasets predicts sequencing failure and batch effects and hampers extracellular vesicle-sRNA analysis". Journal of Extracellular Biology 2 6 (2023): http://dx.doi.org/10.1002/jex2.91.
    10.1002/jex2.91
  3. Maqueda, Joaquín J.; Santos, Mafalda; Ferreira, Marta; Marinho, Sérgio; Rocha, Sara; Rocha, Mafalda; Saraiva, Nadine; et al. "NGS Data Repurposing Allows Detection of tRNA Fragments as Gastric Cancer Biomarkers in Patient-Derived Extracellular Vesicles". International Journal of Molecular Sciences 24 10 (2023): 8961. http://dx.doi.org/10.3390/ijms24108961.
    10.3390/ijms24108961
  4. Dias Carvalho, Patrícia; Martins, Flávia; Mendonça, Susana; Ribeiro, Andreia; Machado, Ana Luísa; Carvalho, Joana; Oliveira, Maria José; Velho, Sérgia. "Mutant KRAS modulates colorectal cancer cells invasive response to fibroblast-secreted factors through the HGF /C-MET axis". International Journal of Cancer [IF: 7.316 Q1 Oncology] (2022): http://dx.doi.org/10.1002/ijc.34225.
    10.1002/ijc.34225
  5. Mafalda Santos; Marta Ferreira; Patrícia Oliveira; Nuno Mendes; Ana André; André F. Vieira; Joana B. Nunes; et al. "Epithelial-Mesenchymal Plasticity Induced by Discontinuous Exposure to TGFß1 Promotes Tumour Growth". Biology [IF: 5.168 Q1 Biology] (2022): https://doi.org/10.3390/biology11071046.
    10.3390/biology11071046
  6. Patrícia Dias Carvalho; Flávia Martins; Joana Carvalho; Maria José Oliveira; Sérgia Velho. "Mutant KRAS-Associated Proteome Is Mainly Controlled by Exogenous Factors". Cells [IF: 7.666 Q2 Cell Biology] 11 13 (2022): 1988-1988. https://doi.org/10.3390/cells11131988.
    10.3390/cells11131988
  7. Rocha, Sara; Basto, Afonso P; Ijsselsteijn, Marieke E; Teles, Sara P; Azevedo, Maria M; Gonçalves, Gilza; Gullo, Irene; et al. "Immunophenotype of Gastric Tumors Unveils a Pleiotropic Role of Regulatory T Cells in Tumor Development". Cancers [IF:6.575 Q1 Oncology] 13 3 (2021): 421. http://dx.doi.org/10.3390/cancers13030421.
    10.3390/cancers13030421
  8. Carvalho, Joana; Oliveira, Patricia; Senz, Janine; São José, Celina; Hansford, Samantha; Teles, Sara Pinto; Ferreira, Marta; et al. "Redefinition of familial intestinal gastric cancer: clinical and genetic perspectives". Journal of Medical Genetics [IF: 5.945; Q1 Genetics & Heredity] (2020): jmedgenet-2019. http://dx.doi.org/10.1136/jmedgenet-2019-106346.
    Published • 10.1136/jmedgenet-2019-106346
  9. Teles, Sara Pinto; Oliveira, Patrícia; Ferreira, Marta; Carvalho, Joana; Ferreira, Pedro; Oliveira, Carla. "Integrated Analysis of Structural Variation and RNA Expression of FGFR2 and Its Splicing Modulator ESRP1 Highlight the ESRP1amp-FGFR2norm-FGFR2-IIIchigh Axis in Diffuse Gastric Cancer". Cancers (IF: 6.575; Q1 Oncology) 12 1 (2019): 70. http://dx.doi.org/10.3390/cancers12010070.
    Published • 10.3390/cancers12010070
  10. Rocha, Sara; Teles, Sara Pinto; Azevedo, Mafalda; Oliveira, Patrícia; Carvalho, Joana; Oliveira, Carla. "Gastric Cancer Extracellular Vesicles Tune the Migration and Invasion of Epithelial and Mesenchymal Cells in a Histotype-Dependent Manner". International Journal of Molecular Sciences [IF: 6.208 Q1 Biochemistry & Molecular Biology] 20 11 (2019): 2608. http://dx.doi.org/10.3390/ijms20112608.
    10.3390/ijms20112608
  11. Bustos-Carpinteyro, Andrea Rebeca; Oliveira, Carla; Sousa, Abel; Oliveira, Patricia; Pinheiro, Hugo; Carvalho, Joana; Magaña-Torres, María Teresa; et al. "CDH1 somatic alterations in Mexican patients with diffuse and mixed sporadic gastric cancer". BMC Cancer [IF: 4.638; Q2 Oncology] 19 1 (2019): http://dx.doi.org/10.1186/s12885-019-5294-0.
    Published • 10.1186/s12885-019-5294-0
  12. Rocha, Sara; Carvalho, Joana; Oliveira, Patrícia; Voglstaetter, Maren; Schvartz, Domitille; Thomsen, Andreas R.; Walter, Nadia; et al. "3D Cellular Architecture Affects MicroRNA and Protein Cargo of Extracellular Vesicles". Advanced Science [IF: 17.521; Q1 Materials Science, Multidisciplinary] 6 4 (2018): 1800948. http://dx.doi.org/10.1002/advs.201800948.
    Published • 10.1002/advs.201800948
  13. Gullo, Irene; Carvalho, Joana; Martins, Diana; Lemos, Diana; Monteiro, Ana; Ferreira, Marta; Das, Kakoli; et al. "The Transcriptomic Landscape of Gastric Cancer: Insights into Epstein-Barr Virus Infected and Microsatellite Unstable Tumors". International Journal of Molecular Sciences [IF: 6.208; Q1 Biochemistry & Molecular Biology] 19 7 (2018): 2079. http://dx.doi.org/10.3390/ijms19072079.
    Published • 10.3390/ijms19072079
  14. Lima, Joana Filipa; Carvalho, Joana; Pinto-Ribeiro, Inês; Almeida, Carina; Wengel, Jesper; Cerqueira, Laura; Figueiredo, Céu; Oliveira, Carla; Azevedo, Nuno Filipe. "Targeting miR-9 in gastric cancer cells using locked nucleic acid oligonucleotides". BMC Molecular Biology [IF: 4.619; Q2 Biochemistry & Molecular Biology] 19 1 (2018): http://dx.doi.org/10.1186/s12867-018-0107-6.
    Published • 10.1186/s12867-018-0107-6
  15. Santos, Mafalda; Pereira, Patricia M.; Varanda, A. Sofia; Carvalho, Joana; Azevedo, Mafalda; Mateus, Denisa D.; Mendes, Nuno; et al. "Codon misreading tRNAs promote tumor growth in mice". RNA Biology [IF: 4.766; Q2 Biochemistry & Molecular Biology] (2018): 1-14. http://dx.doi.org/10.1080/15476286.2018.1454244.
    10.1080/15476286.2018.1454244
  16. Gullo, Irene; Oliveira, Patrícia; Athelogou, Maria; Gonçalves, Gilza; Pinto, Marta L.; Carvalho, Joana; Valente, Ana; et al. "New insights into the inflamed tumor immune microenvironment of gastric cancer with lymphoid stroma: from morphology and digital analysis to gene expression". Gastric Cancer [IF: 7.701; Q1 Gastroenterology & Hepatology] 22 1 (2018): 77-90. http://dx.doi.org/10.1007/s10120-018-0836-8.
    Published • 10.1007/s10120-018-0836-8
  17. Fais, S.; O'Driscoll, L.; Borras, F.E.; Buzas, E.; Camussi, G.; Cappello, F.; Carvalho, J.; et al. "Evidence-Based Clinical Use of Nanoscale Extracellular Vesicles in Nanomedicine". ACS Nano [IF: 18.027; Q1 Nanoscience & Nanotechnology] 10 4 (2016): 3886-3899. http://www.scopus.com/inward/record.url?eid=2-s2.0-84968866526&partnerID=MN8TOARS.
    10.1021/acsnano.5b08015
  18. Oliveira, P.; Carvalho, J.; Rocha, S.; Azevedo, M.; Reis, I.; Camilo, V.; Sousa, B.; et al. "Dies1/VISTA expression loss is a recurrent event in gastric cancer due to epigenetic regulation". Scientific Reports (IF: 4.997; Q1 Multidisciplinary Sciences) 6 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84990946691&partnerID=MN8TOARS.
    10.1038/srep34860
  19. Queirós, P.; Pinheiro, H.; Carvalho, J.; Oliveira, P.; Gullo, I.; Carneiro, F.; Almeida, G.M.; Oliveira, C.. "KRAS mutations in microsatellite instable gastric tumours: impact of targeted treatment and intratumoural heterogeneity". Virchows Archiv [IF: 4.548; Q2 Pathology] 467 4 (2015): 383-392. http://www.scopus.com/inward/record.url?eid=2-s2.0-84944513629&partnerID=MN8TOARS.
    10.1007/s00428-015-1823-7
  20. Hansford, S.; Kaurah, P.; Li-Chang, H.; Woo, M.; Senz, J.; Pinheiro, H.; Schrader, K.A.; et al. "Hereditary diffuse gastric cancer syndrome: CDH1 mutations and beyond". JAMA Oncology [IF: 33.012; Q1 Oncology] 1 1 (2015): 23-32. http://www.scopus.com/inward/record.url?eid=2-s2.0-84989787164&partnerID=MN8TOARS.
    10.1001/jamaoncol.2014.168
  21. Carvalho, J.; Oliveira, C.. "Extracellular Vesicles - Powerful markers of cancer EVolution". Frontiers in Immunology [IF: 7.787; Q1 Immunology] 6 JAN (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84926638210&partnerID=MN8TOARS.
    10.3389/fimmu.2014.00685
  22. Yáñez-Mó, M.; Siljander, P.R.-M.; Andreu, Z.; Zavec, A.B.; Borràs, F.E.; Buzas, E.I.; Buzas, K.; et al. "Biological properties of extracellular vesicles and their physiological functions". Journal of Extracellular Vesicles [IF: 17.367; Q1 Cell Biology] 4 2015 (2015): 1-60. http://www.scopus.com/inward/record.url?eid=2-s2.0-85014619748&partnerID=MN8TOARS.
    10.3402/jev.v4.27066
  23. Corso, G.; Carvalho, J.; Marrelli, D.; Vindigni, C.; Carvalho, B.; Seruca, R.; Roviello, F.; Oliveira, C.. "Somatic mutations and deletions of the E-cadherin gene predict poor survival of patients with gastric cancer". Journal of Clinical Oncology [IF: 50.739; Q1 Oncology] 31 7 (2013): 868-875. http://www.scopus.com/inward/record.url?eid=2-s2.0-84875753760&partnerID=MN8TOARS.
    10.1200/JCO.2012.44.4612
  24. Carneiro, P.; Figueiredo, J.; Bordeira-Carriço, R.; Fernandes, M.S.; Carvalho, J.; Oliveira, C.; Seruca, R.. "Therapeutic targets associated to E-cadherin dysfunction in gastric cancer". Expert Opinion on Therapeutic Targets (IF: 6.797; Q1 Pharmacology & Pharmacy) 17 10 (2013): 1187-1201. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884582960&partnerID=MN8TOARS.
    10.1517/14728222.2013.827174
  25. Pinheiro, H.; Carvalho, J.; Oliveira, P.; Ferreira, D.; Pinto, M.T.; Osoquot;rio, H.; Licastro, D.; et al. "Transcription initiation arising from E-cadherin/CDH1 intron2: A novel protein isoform that increases gastric cancer cell invasion and angiogenesis". Human Molecular Genetics [IF: 5.121; Q1 Genetics & Heredity] 21 19 (2012): 4253-4269. http://www.scopus.com/inward/record.url?eid=2-s2.0-84866408689&partnerID=MN8TOARS.
    10.1093/hmg/dds248
  26. Carneiro, P.; Fernandes, M.S.; Figueiredo, J.; Caldeira, J.; Carvalho, J.; Pinheiro, H.; Leite, M.; et al. "E-cadherin dysfunction in gastric cancer - Cellular consequences, clinical applications and open questions". FEBS Letters [IF: 3.864; Q2 Biophysics] 586 18 (2012): 2981-2989. http://www.scopus.com/inward/record.url?eid=2-s2.0-84864922992&partnerID=MN8TOARS.
    10.1016/j.febslet.2012.07.045
  27. Lopes, N.; Carvalho, J.; Durães, C.; Sousa, B.; Gomes, M.; Costa, J.L.; Oliveira, C.; Paredes, J.; Schmitt, F.. "1Alpha,25-dihydroxyvitamin D3 induces de novo E-cadherin expression in triple-negative breast cancer cells by CDH1-promoter demethylation". Anticancer Research [IF: 2.435; Q3 Oncology] 32 1 PART 2 (2012): 249-257. http://www.scopus.com/inward/record.url?eid=2-s2.0-84856024024&partnerID=MN8TOARS.
  28. Carvalho, J.; Van Grieken, N.C.; Pereira, P.M.; Sousa, S.; Tijssen, M.; Buffart, T.E.; Diosdado, B.; et al. "Lack of microRNA-101 causes E-cadherin functional deregulation through EZH2 up-regulation in intestinal gastric cancer". Journal of Pathology (IF: 9.883; Q1 Oncology) 228 1 (2012): 31-44. http://www.scopus.com/inward/record.url?eid=2-s2.0-84864749110&partnerID=MN8TOARS.
    10.1002/path.4032
  29. Paredes, J.; Figueiredo, J.; Albergaria, A.; Oliveira, P.; Carvalho, J.; Ribeiro, A.S.; Caldeira, J.; et al. "Epithelial E- and P-cadherins: Role and clinical significance in cancer". Biochimica et Biophysica Acta - Reviews on Cancer [IF: 11.414; Q1 Biochemistry & Molecular Biology] 1826 2 (2012): 297-311. http://www.scopus.com/inward/record.url?eid=2-s2.0-84861800037&partnerID=MN8TOARS.
    10.1016/j.bbcan.2012.05.002
  30. Pinheiro, H.; Bordeira-Carriço, R.; Seixas, S.; Carvalho, J.; Senz, J.; Oliveira, P.; Inácio, P.; et al. "Allele-specific CDH1 downregulation and hereditary diffuse gastric cancer". Human Molecular Genetics [IF: 5.121; Q1 Genetics & Heredity] 19 5 (2010): 943-952. http://www.scopus.com/inward/record.url?eid=2-s2.0-77950533734&partnerID=MN8TOARS.
    10.1093/hmg/ddp537
  31. Oliveira, C.; Sousa, S.; Pinheiro, H.; Karam, R.; Bordeira-Carriço, R.; Senz, J.; Kaurah, P.; et al. "Quantification of Epigenetic and Genetic 2nd Hits in CDH1 During Hereditary Diffuse Gastric Cancer Syndrome Progression". Gastroenterology [IF: 33.883; Q1 Gastroenterology & Hepatology] 136 7 (2009): 2137-2148. http://www.scopus.com/inward/record.url?eid=2-s2.0-66149108352&partnerID=MN8TOARS.
    10.1053/j.gastro.2009.02.065
  32. Karam, R.; Carvalho, J.; Bruno, I.; Graziadio, C.; Senz, J.; Huntsman, D.; Carneiro, F.; et al. "The NMD mRNA surveillance pathway downregulates aberrant E-cadherin transcripts in gastric cancer cells and in CDH1 mutation carriers". Oncogene (IF: 8.756; Q1 Genetics & Heredity) 27 30 (2008): 4255-4260. http://www.scopus.com/inward/record.url?eid=2-s2.0-47049115051&partnerID=MN8TOARS.
    10.1038/onc.2008.62
Preprint
  1. Martins, Flávia; Machado, Ana Luísa; Ribeiro, Andreia; Oliveira, Susana Mendonça; Carvalho, Joana; Matthiesen, Rune; Backman, Vadim; Velho, Sérgia. "KRAS silencing impacts chromatin organization and transcriptional activity in colorectal cancer cells". 2024. http://dx.doi.org/10.21203/rs.3.rs-3752760/v2.
    10.21203/rs.3.rs-3752760/v2
  2. Susana Mendonça Oliveira; Patrícia Dias Carvalho; André Roma; Patrícia Oliveira; Andreia Ribeiro; Joana Carvalho; Flávia Martins; et al. "Unveiling the Mechanisms to Bypass KRAS Inhibition:In VitroInsights into the Influence of Fibroblast-Secretome". 2024. https://doi.org/10.1101/2024.04.19.590324.
    10.1101/2024.04.19.590324
  3. Patrícia Dias Carvalho; Flávia Martins; Joana Carvalho; Maria José Oliveira; Sérgia Velho. "Mutant KRAS-associated proteome is mainly controlled by exogenous factors". 2022. https://doi.org/10.1101/2022.01.05.475056.
    10.1101/2022.01.05.475056
Thesis / Dissertation
  1. Carvalho, Joana. "The involvement of microRNAs in Gastric Cancer". PhD, Universidade do Porto Faculdade de Medicina, 2012.

Other

Other output
  1. Mutant KRAS modulates colorectal cancer cells invasive response to fibroblast-secreted factors through the HGF/C-MET axis. 2021. Patrícia Dias Carvalho; Flávia Martins; Susana Mendonça; Andreia Ribeiro; Ana Luísa Machado; Joana Carvalho; Maria José Oliveira; Sérgia Velho. https://doi.org/10.1101/2021.11.16.468815.
    10.1101/2021.11.16.468815
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2018/06/12 Extracellular Vesicles - (fine) tuning the Gastric Cancer microenvironment The international Cancer Microenvironment Society 2018 Meeting
International Cancer Microenvironment Society (Lisbon, Portugal)
2016 Familial Intestinal Gastric Cancer: search for a germline and somatic cause 20th Meeting of the Portuguese Society of Human Genetics
Sociedade Portuguesa de Genética Humana (Coimbra, Portugal)
2016 Dissecting the (epi)genetic landscapes of Gastric Cancer: on the road to liquid biopsy National Symposium of the Portuguese Oncology Society
Sociedade Portuguesa de Oncologia (Figueira da Foz, Portugal)
2016 Extracellular Vesicles - playing around with the Gastric Cancer microenvironment Third Geivex Symposium
Grupo Español de investigacion en Vesiculas Extracelulares (San Sebastian, Spain)
2013 Extracellular Vesicles: shuttles of Epithelial and Mesenchymal transitions and Cancer Metastasis ME-HAD Cost Meeting
European Network on Microvesicles and Exosomes in Health and Disease (Budapest, Hungary)
2012 Modulating the expression and function of E-cadherin in Gastric cancer: classical and alternative mechanisms 2º Encontro de Doutorandos da FMUP
Faculdade Medicina Universidade do Porto (Porto, Portugal)
2012 Can microRNAs regulate the E-cadherin-Catenin Complex in Gastric Cancer? Portuguese RNA meeting 2012
(Lisboa, Portugal)
2009 miR-101 - EZH2 - CDH1: Do they fit together in the context of Gastric Cancer? 6th International Medical Postgraduate Conference
(Hradec Kralove, Czech Republic)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2022/12/01 - Current Canine gastric cancer: CDH1 genetics and proteome approach
Co-supervisor
 Ciências Veterinárias (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2020/01/01 - Current Identification of therapeutic targets and disease biomarkers for mutant KRAS cancer patients: fulfilling an unmet clinical need
Co-supervisor
 Biomedicina (PhD)
Universidade do Porto Faculdade de Medicina, Portugal
2022/09/01 - 2023/10/31 Understanding the role of EVs derived from KRAS mutated cancer cells on T-cell exhaustion
Supervisor
 Investigação Biomédica (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2016/01/01 - 2020/07/17 Deconstructing Gastric Cancer Colonization: the interplay between immune cells, gastric cancer cells and extracellular vesicles
Co-supervisor
 Biotecnologia Molecular e Celular Aplicada às Ciências da Saúde (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2020/02/12 - 2020/07/14 TGFß1 functional polymorphisms as predictive biomarkers of response to immunotherapy
Co-supervisor
 Bioquímica (Degree)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2016/09/01 - 2017/11/30 The Germline and Somatic landscape of Familial Intestinal Gastric Cancer: search for a cause
Co-supervisor
 Oncologia (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2015/09/30 - 2015/09/30 Co-organization of the First Iberian Meeting on Extracellular Vesicles (2015/09/30 - 2015/09/30)
Meeting (Member of the Organising Committee)
 Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2023 - Current Science Ambassador at i3S Educational Program
Other
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2007 - 2018 Participation in programs organized by "Ciência Viva"
Other
 Ciência Viva no Laboratório - Ocupação Científica de Jovens nas Férias
Ciência Viva, Portugal

Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
2017/04 - 2017/04 Moderator of the Cancer Genetics and Epigenetics session in the 1st Symposium of the Master Course in Oncology
Symposium
 1st Symposium of the Master Course in Oncology -Porto
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
2014/11/14 - 2014/11/15 Dissemination to general public information about gastric cancer aetiology, prevention and early detection.
Exhibition
 Ipatimup - 2 Dias Abertos
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
2014/05/05 - 2014/05/12 Exhibition for the general public in order to increase people's literacy regarding health and cancer problems, aiming to stimulate prevention and early diagnosis of the disease
Exhibition
 Cancro, Ciência e Cidade: Os Passos da Ciência nos Paços do Concelho
Câmara Municipal do Porto, Portugal

Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2021/11/16 Impacto das diferentes variáveis pré-analíticas e analíticas na análise de amostras de sangue utilizando a impressão digital ótica
(Thesis) Main arguer
 Gabrielle Cabral de Lacerda (Master)
Universidade do Porto Faculdade de Ciências, Portugal
2017/12/05 Unraveling the role of lymphotoxin signaling in T-cell acute leukemia molecular crosstalk with microenvironmental cells
(Thesis) Arguer
 Marta Alexandra Senra Araújo (Master)
Universidade do Minho, Portugal
2017/07/13 Cancer-associated fibroblasts and tumor-associated macrophages: exploring their mutual regulation
(Thesis) Main arguer
 Carlos Ferreira Guimarães (Master)
Universidade do Porto Faculdade de Engenharia, Portugal
2014/12 Regulation of MCL1 alternative polyadenylation- derived mRNA isoforms by microRNAs in human T cells
(Thesis) Main arguer
 Ana Curinha de Sousa (Master)
Universidade de Aveiro Departamento de Biologia, Portugal
2013/12 Silencing ability of tRNA derived fragments in Zebrafish
(Thesis) Main arguer
 Noémia Fernandes (Master)
Universidade de Aveiro Departamento de Biologia, Portugal

Ad Hoc journal article review

Journal title (ISSN) Publisher
2020 - Current Cancers
2017 - Current Clinical Epigenetics (1868-7083) Springer-Verlag
2015 - Current International Journal of Cancer (1097-0215) Wiley (John Wiley & Sons)
2015 - Current PLoS ONE (1932-6203) Public Library of Science
2013 - Current Gut (1468-3288) BMJ
2013 - Current BMC Cancer (1471-2407) Springer (Biomed Central Ltd.)
2013 - Current International Journal of Molecular Sciences (1422-0067) MDPI AG
2012 - Current Cellular Oncology (1875-8606) IOS Press

Association member

Society Organization name Role
2024/02/15 - Current Portuguese Oncology Society Effective member
2014 - Current Grupo Español de investigacion en Vesiculas Extracelulares (GEIVEX)
2014 - Current International Society for Extracellular Vesicles (ISEV)
2013 - Current Associação Portuguesa de Investigação em Cancro (ASPIC)
2012 - Current European Association for Cancer Research (EACR)
2011 - Current European Society of Human Genetics (ESHG)
2011 - Current Sociedade Portuguesa de Genética Humana (SPGH)

Committee member

Activity description
Role 		Institution / Organization
2013 - 2017 Management Committee of Microvesicles and Exosomes in Health & Disease - BMBS COST Action BM1202 (http://bit.ly/2k2bKoM), 2013-2017. Role: MC substitute
Member

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2019 - 2021 Vesículas Extracelulares: o seu papel na invasão e metastização (Cadeira Opcional Invasão e Metastização) Medicina (Mestrado integrado) Universidade do Porto Faculdade de Medicina, Portugal
2017/12 - 2017/12 The role of Exosomes in Gastric Cancer - Advance Course on Intercellular Communication (Outros) Universidade de Coimbra Faculdade de Medicina, Portugal
2015/05 - 2015/05 Exosomes: their role in epithelial and mesenchymal transitions and tumour progression - Oncobiology Conferences (Outros) Universidade do Porto Faculdade de Farmácia, Portugal
2014/11 - 2014/11 Epithelial to Mesenchymal Transition - Molecular Oncology Course: Cancer Biology and Emergent Therapies (Outros) Instituto Português de Oncologia de Coimbra Francisco Gentil EPE, Portugal
2014 - 2014 Cancer cell communication and Exosomes - GABBA Program - Oncobiology Module at Ipatimup GABBA Program (Curso de doutoramento (conclusão de unidades curriculares)) Universidade do Porto, Portugal

Journal scientific committee

Journal title (ISSN) Publisher
2023 - Current Frontiers in Oncology _ Review editor
2021 - 2022/12/31 Cells - Guest Editor Special Issue "The Interaction between Stromal Cells and Tumor Cells"

Mentoring / Tutoring

Topic Student name
2022 - 2023 Non-invasive monitoring of metastatic colorectal cancer in Circulating Tumor DNA and Exosomal RNA Nuno Antunes Bonito, MD, MSc student
2019 - 2019 Monitorização de alterações moleculares em doentes com cancro colorectal metastizado ao longo do curso da terapêutica instituída Inês Brandão Rego, MD
2017 - 2018 Predicting outcome and therapy response in metastatic colorectal cancer patients using liquid biopsy - Leonor Pinto, MD
2017/04/03 - 2017/04/21 miRNAs characterization from 2D and 3D cell culture exosomes and labelling and internalization assays optimization of exosomes in cell culture models Carlos Alberto Gaspar de Jesus, MSc student
2016 - 2016 Characterization of exosomes derived from gastric cancer and breast cancer cells cultured in 2D versus 3D conditions Richa Khanduri, PhD student
2013/10/01 - 2014/11/30 Dies1 gene expression and regulation in Gastric Cancer Inês Calado Reis, MSc student
2014/02/01 - 2014/09/30 Establishment of a 3D model of EMT/MET induction using molecularly-designed ECM-like hydrogels Sara Jorge Moreira da Rocha, MSc student
2011/07/01 - 2012/04/30 Expression analysis of microRNAs targeting adhesion complex molecules in gastric cancer Pedro Nuno Pereira e Freitas, MSc student

Other jury / evaluation

Activity description Institution / Organization
2015/06 - Current Seminar Examination (Main arguer) Diana Duarte de Sousa - "Intercellular transfer of cancer drug resistance traits by extracellular vesicles "- PhD in Pharmaceutical Sciences from Faculty of Pharmacy of University of Porto Universidade do Porto Faculdade de Farmácia, Portugal
2023/05/10 - 2023/05/12 Scientific Moderator of Health Sciences session in the IJUP'23 - 16th Youth Research Meeting of the University of Porto
2018 - 2018 Abstract Reviewer for the European Human Genetics Conference 2018 European Society of Human Genetics, Austria
2017/05 - 2017/05 Moderator and evaluator of Speed Talks in the 24th Porto Cancer Meeting Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
2015/09/30 - 2015/09/30 Evaluator of abstracts of the First Iberian Meeting on Extracellular Vesicles
Distinctions

Award

2021 Pulido Valente Science 2020 Prize - Co-first author of a Best Scientific paper in Biomedical Sciences
Fundação para a Ciência e a Tecnologia, Portugal

Fundação Francisco Pulido Valente, Portugal
2016 Best work on the topic: Other Tumours - Simpósio Nacional SPO, Figueira da Foz, Portugal
Sociedade Portuguesa de Oncologia, Portugal

Other distinction

2019 Best oral communication (co-author) - 15º Congresso Nacional Cancro Digestivo
2017 Travel Grant Award 25th UEG Week, Barcelona, Spain
United European Gastroenterology, Austria
2016 National European Society of Human Genetics Fellowship - 20ª Reunião Anual SPGH, Coimbra, Portugal
2011 Poster award finalist - European Human Genetics Conference 2011, Amsterdam, The Netherlands
2009 Second best oral presentation - 6th International Medical Postgraduate Conference - New Frontiers in the Research of PhD Students, Hradec Kralove, Prague
2008 Short term fellowship - Gulbenkian Foundation
Fundação Calouste Gulbenkian, Portugal
2008 Short term fellowship - European Molecular Biology Organization
Gesellschaft zur Förderung der Lebenswissenschaften Heidelberg GmbH, Germany