Curriculum Vitae
Isabel Maria Pereira Doutor
Identification
Personal identification
- Full name
- Isabel Maria Pereira Doutor
Citation names
- Doutor, Isabel
Author identifiers
- Ciência ID
- 5E1E-ED6C-6AD7
- ORCID iD
- 0000-0002-2807-6619
Email addresses
- isabel.doutor@tecnico.ulisboa.pt (Professional)
Websites
- http://scerg.tecnico.ulisboa.pt/idoutor.html (Professional)
- https://www.linkedin.com/in/isabel-doutor/ (Professional)
Knowledge fields
- Natural sciences - Biological Sciences
- Engineering and Technology - Chemical Engineering - Chemical Process Engineering
- Medical and Health Sciences - Medical Biotechnology - Health-Related Biotechnology
- Medical and Health Sciences - Basic Medicine - Immunology
Languages
| Language | Speaking | Reading | Writing | Listening | Peer-review |
|---|---|---|---|---|---|
| Portuguese (Mother tongue) | |||||
| English | Upper intermediate (B2) | Advanced (C1) | Upper intermediate (B2) | Upper intermediate (B2) | Upper intermediate (B2) |
| Spanish; Castilian | Intermediate (B1) | Upper intermediate (B2) | Intermediate (B1) | Intermediate (B1) | Intermediate (B1) |
| French | Intermediate (B1) | Upper intermediate (B2) | Intermediate (B1) | Intermediate (B1) | Intermediate (B1) |
| Dutch | Beginner (A1) | Elementary (A2) | Beginner (A1) | Beginner (A1) | Beginner (A1) |
Education
| Degree | Classification | |
|---|---|---|
|
2021/04 - 2025
Ongoing
|
Bioengenharia - Terapias Celulares e Medicina Regenerativa (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
|
|
|
2014/09 - 2019/11/18
Concluded
|
Engenharia Biológica (Mestrado integrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
"Co-Culture Strategies Mimicking the Fetal Liver Niche for In Vitro Expansion of Hematopoietic Stem Cells" (THESIS/DISSERTATION)
|
17 |
|
2019/02/10 - 2019/07/10
Concluded
|
Engenharia Biológica (Master)
Katholieke Universiteit Leuven Faculteit Geneeskunde, Belgium
"Co-Culture Strategies Mimicking the Fetal Liver Niche for In Vitro Expansion of Hematopoietic Stem Cells" (THESIS/DISSERTATION)
|
18 |
Affiliation
Science
| Category Host institution |
Employer | |
|---|---|---|
| 2021/04/05 - 2025/04/05 | Researcher (Research) | Universidade de Lisboa Instituto Superior Técnico, Portugal |
| Universidade de Lisboa Instituto de Bioengenharia e Biociências, Portugal |
Others
| Category Host institution |
Employer | |
|---|---|---|
| 2019/02/10 - 2019/07/10 | ERASMUS Student Researcher, "Co-Culture Strategies Mimicking the Fetal Liver Niche for In Vitro Expansion of Hematopoietic Stem Cells" (Master Thesis) | Katholieke Universiteit Leuven Faculteit Geneeskunde, Belgium |
| Katholieke Universiteit Leuven Faculteit Geneeskunde, Belgium (...) |
||
| 2018/07 - 2018/09 | Student Researcher, "Biological Activity Study of Cynara cardunculus Leaves Extracts: In Vitro Cell Assays" | Centro de Biotecnologia Agrícola e Agro-Alimentar do Alentejo, Portugal |
| Centro de Biotecnologia Agrícola e Agro-Alimentar do Alentejo, Portugal | ||
| 2017/09 - 2018/07 | Student Researcher, "Bioengineering Strategies for Pluripotent Stem Cell Expansion and Differentiation" | Universidade de Lisboa Instituto de Bioengenharia e Biociências, Portugal |
| Universidade de Lisboa Instituto de Bioengenharia e Biociências, Portugal (...) |
||
| 2017/07/03 - 2017/09/15 | Student Researcher, "Characterization and Selective Fractionation of Relevant Lignocellulosic Materials from the Alentejo Region within the Biorefinaria Concept" | Centro de Biotecnologia Agrícola e Agro-Alimentar do Alentejo, Portugal |
| Centro de Biotecnologia Agrícola e Agro-Alimentar do Alentejo, Portugal |
Projects
Grant
| Designation | Funders | |
|---|---|---|
| 2021/04/05 - 2025/04/04 | Technology-driven platform for the manufacturing of extracellular vesicles derived from umbilical cord blood CARengineered
NK cells for immunotherapy
UI/BD/151248/2021
PhD Student Fellow
|
Fundação para a Ciência e a Tecnologia
Ongoing
|
| 2022 - 2024 | NKBoost - Quality by design-centered platform for the manufacturing of CAR-engineered NK cells and extracellular vesicles
for immunotherapy
PTDC/EQU-EQU/3708/2021
Integration into Research Grant Fellow
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal
Universidade de Lisboa Instituto Superior Técnico, Portugal |
Fundação para a Ciência e a Tecnologia
Ongoing
|
Other
| Designation | Funders | |
|---|---|---|
| 2018/07 - 2018/09 | ValBioTecCynara - Valorização económica do cardo (Cynara cardunculus): variabilidade natural e suas aplicações biotecnológicas
ALT20-03-0145- FEDER-000038
Other
Centro de Biotecnologia Agrícola e Agro-Alimentar do Alentejo, Portugal
|
Ongoing
|
| 2017/07 - 2017/09 | SelecTEcoli - Seleção e caraterização de estirpes de E. coli com tolerância acrescida a multi-inibidores derivados dos processos
de pré-tratamento da biomassa lenhocelulósica
ALT20-03-0145-FEDER-000034
Other
Centro de Biotecnologia Agrícola e Agro-Alimentar do Alentejo, Portugal
|
Ongoing
|
Outputs
Publications
| Conference paper |
|
| Conference poster |
|
| Thesis / Dissertation |
|
Activities
Oral presentation
| Presentation title | Event name Host (Event location) |
|
|---|---|---|
| 2024/06 | Cord blood natural killer cells: a promising source of cytotoxic extracellular vesicles for cancer immunotherapy | 28th ESACT Meeting
(Edinburgh, United Kingdom)
|
| 2023/11/14 | Development of a manufacturing platform for umbilical cord blood natural killer cells and derived extracellular vesicles for immunotherapy | 7ª Conferência Anual da RedeSaúde
(Lisbon, Portugal)
|
| 2023/11/13 | Umbilical cord blood natural killer cells and derived extracellular vesicles manufacturing platform for immunotherapy | III iBB Workshop
(Lisbon, Portugal)
|
| 2023/07/14 | Umbilical Cord Blood Natural Killer Cells and Derived Extracellular Vesicles for Immunotherapy: Optimizing Cell Expansion and EV Production and Isolation | SNEV Virtual Conference
Student Network on Extracellular Vesicles
|
| 2023/06/02 | Impact of culture media on the expansion and functionality of umbilical cord blood natural killer cells and derived extracellular vesicles | 2nd Meeting of the Portuguese Network on Extracellular Vesicles
Portuguese Network on Extracellular Vesicles (Lisbon, Portugal)
|
| 2023/01/11 | Optimization of the Ex Vivo Expansion of Umbilical Cord Blood Natural Killer Cells and Production of Derived Extracellular Vesicles Under Static Conditions | 33rd Annual Meeting ESACT-UK 2023
ESACT-UK (Nottingham, United Kingdom)
|
| 2022/11/15 | Technology-driven manufacturing platform of EVs derived from UCB CAR-engineered NK cells for immunotherapy | PhD Open Days
Instituto Superior Técnico (Lisbon, Portugal)
|
Event participation
| Activity description Type of event |
Event name Institution / Organization |
|
|---|---|---|
| 2023/11/14 - Current | 7ª Conferência Anual da RedeSaúde: "Viver em Qualidade: Valor em Saúde e Bem-Estar" | 7ª Conferência Anual da RedeSaúde |
| 2023/11/13 - Current | III iBB Workshop
Conference
|
III iBB Workshop
Universidade de Lisboa Instituto de Bioengenharia e Biociências, Portugal
|
| 2023/11/11 - Current | IST-Taguspark Open Day: We had the chance to show the facilities of the stem cell engineering and regenerative medicine laboratory
to a diverse group of enthusiasts of all ages and share the potential of stem cell research with aspiring young scientists
and curious minds.
Other
|
IST-Taguspark Open Day |
| 2023/06/26 - Current | GEIVEX Workshop: Clinical Translation Of EV-Based Therapeutic Products: This workshop focused on giving a first grasp of the
steps needed for clinical translation for EV-based products. The sessions included GMP basics and requirements to regulatory
issues and the industry viewpoint, given by experts in the field of cell and gene therapy, clinical and regulatory bodies.
Workshop
|
GEIVEX Workshop: Clinical Translation Of EV-Based Therapeutic Products |
| 2022/09/23 - Current | II iBB Workshop
Conference
|
II iBB Workshop |
| 2024/09/18 - 2024/09/19 | CIMT Cancer Cell Therapy Summit
Conference
|
Fundação Champalimaud, Portugal
|
| 2024/06/23 - 2024/06/26 | 28th ESACT Meeting
Meeting
|
28th European Society for Animal Cell Technology Meeting |
| 2024/03/10 - 2024/03/15 | Tiny Packages with Big Impact: Workshop on EVs Separation and Characterization
Workshop
|
Tiny Packages with Big Impact: Workshop on EVs Separation and Characterization
University of Virginia School of Medicine, United States
|
| 2023/10/24 - 2023/10/27 | ESGCT 30th Annual Congress
Congress
|
ESGCT 30th Annual Congress
Europen Society of Gene & Cell Therapy, United Kingdom
|
| 2023/07/13 - 2023/07/14 | SNEV Virtual Conference
Conference
|
SNEV Virtual Conference |
| 2023/06/22 - 2023/06/23 | 2nd Meeting of the Portuguese Network on Extracellular Vesicles
Meeting
|
2nd Meeting of the Portuguese Network on Extracellular Vesicles
Universidade Nova de Lisboa Nova Medical School, Portugal
|
| 2023/05/24 - 2023/05/25 | Flow Cytometry Facility User Training
Other
|
Flow Cytometry Facility User Training |
| 2023/04/26 - 2023/04/28 | Training in Science Communication: An additional stimulus to develop training in science communication, as well as fostering
dialogue between science and society (https://www.ulisboa.pt/evento/formacao-em-comunicacao-de-ciencia).
Other
|
Training in Science Communication
Universidade de Lisboa, Portugal
|
| 2023/03/29 - 2023/03/31 | XLVIII Annual Meeting of the Portuguese Society for Immunology
Meeting
|
XLVIII Annual Meeting of the Portuguese Society for Immunology |
| 2023/01/11 - 2023/01/12 | 33rd Annual Meeting ESACT-UK 2023
Conference
|
33rd Annual Meeting ESACT-UK 2023 |
| 2022/11/14 - 2022/11/16 | PhD Open Days: An opportunity for more than one thousand PhD students to socialize and share their research with the rest
of the academic community, companies, and alumni.
Meeting
|
PhD Open Days
Universidade de Lisboa Instituto Superior Técnico, Portugal
|
| 2022/07/11 - 2022/07/15 | Advanced Therapies Summer Course: The aim of this course was the diffusion of knowledge about Advanced Therapies (gene therapy,
somatic cell therapy, tissue engineering), and their therapeutic possibilities, with a special emphasis on their current applications
in the field of genetic and neoplastic diseases as well as regenerative medicine.
Other
|
Advanced Therapies Summer Course
Universidad de Murcia, Spain
|
| 2022/06/26 - 2022/06/29 | 27th ESACT Meeting of the European Society for Animal Cell Technology
Conference
|
27th ESACT Meeting of the European Society for Animal Cell Technology |
| 2022/03/10 - 2022/03/12 | 12th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies
Meeting
|
12th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies |
| 2019/03 - 2019/03 | Flow Cytometry Facility User Training: This training is composed of a theory and practical instrument training. The theory
covers the basic principles of flow cytometry; instrument components, fluorescence absorption and emission, compensation,
experimental design and appropriate controls for flow cytometry. It also covers more advanced concepts such as multiparameter
experimental design. In the instrument training, users practice using the instrument by running their own stained samples.
Other
|
Flow Cytometry Facility User Training
Katholieke Universiteit Leuven Groep Biomedische Wetenschappen, Belgium
|
| 2018/03/05 - 2018/03/09 | IV Semana da Bioengenharia
Meeting
|
IV Semana da Bioengenharia
Universidade de Lisboa Instituto Superior Técnico, Portugal
|
| 2017/03/06 - 2017/03/10 | III Semana da Bioengenharia
Meeting
|
III Semana da Bioengenharia
Universidade de Lisboa Instituto Superior Técnico, Portugal
|
| 2016/02/29 - 2016/03/04 | II Semana da Bioengenharia (SBE): SBE happens every year at IST and used as a way of spreading both knowledge about what is
done is the bioengineering area and the opportunities of investigation in Portugal and in the world, not only to students
of the referred masters, but to all interested in this topic. This way the SBE is a week full of lectures from investigators
and companies in the bioengineering area, scientific field trips to relevant investigation or industrial facilities, workshops
and international guests, among others.
Meeting
|
II Semana da Bioengenharia
Universidade de Lisboa Instituto Superior Técnico, Portugal
|
Association member
| Society Organization name | Role | |
|---|---|---|
| 2016 - 2018 | Núcleo de Engenharia Biológica | Colaboradora (2016); Coordenadora (2017); Presidente do Conselho Fiscal (2018) |
Course / Discipline taught
| Academic session | Degree Subject (Type) | Institution / Organization | |
|---|---|---|---|
| 2022/11 - 2022/12 | After School - Engenharia Genética e Bioprocessos 2022-02 | (Ensino secundário) |
Mentoring / Tutoring
| Topic | Student name | |
|---|---|---|
| 2023/09 - 2024/06 | UCB-NK cell isolation and expansion and NK-EVs production and isolation | Beatriz Filipe |
| 2023/05 - 2024/02 | UCB-NK cell isolation and expansion | Gabriel Costa |
Distinctions
Award
| 2023 | Best Oral Presentation on the SNEV Virtual Conference |
Other distinction
| 2019 | Aluna de Mérito
Universidade de Lisboa Instituto Superior Técnico, Portugal
|
| 2018 | Aluna de Mérito
Universidade de Lisboa Instituto Superior Técnico, Portugal
|
| 2017 | Aluna de Mérito
Universidade de Lisboa Instituto Superior Técnico, Portugal
|
| 2016 | Aluna de Mérito
Universidade de Lisboa Instituto Superior Técnico, Portugal
|
| 2015 | Aluna de Mérito
Universidade de Lisboa Instituto Superior Técnico, Portugal
|