Flávio Miguel Pereira Costa (5F1E-C8C6-3388)

Curriculum Vitae

Flávio Miguel Pereira Costa

Flávio Costa, MSc in Biochemistry, is currently a Research Technician at Center for Innovative Care and Health Technology (ciTechCare), Polytechnic of Leiria. He has a BSc (2016) and MSc graduation (2019) in Biochemistry, from Faculty of Sciences of University of Porto and Abel Salazar Biomedical Sciences Institute, Portugal. In his MSc thesis, entitled "On the role of adenosine-sensitive P1 receptors in human chondrogenesis" he he first authored a review entitled “Adenosinergic signalling in chondrogenesis and cartilage homeostasis: Friend or foe?”, published at Biochemical Pharmacology journal (DOI:10.1016/j.bcp.2019.113784) and presented his work at the Portuguese Society of Pharmacology (SPF) 2019 Meeting. He was also invited to lecture Pharmacology practical classes to Medicine, Veterinary Medicine and Bioengineering MSc courses. In 2020, Flávio collaborated in designing and writing a winning project under the RESEARCH4COVID-19 funding call by Fundação para a Ciência e Tecnologia (FCT) with a project entitled “Purinome-rejuvenated autologous STEM cells against COVID-19. Who´s gonna win the ageing battle?”. Results were presented at the European Alliance for Global Health Transformation 2022 Annual Summit, through the joint Research and Innovation Action (EUGLHORIA) Seeding Conference, hosted by Lund University-Sweden. He joined ciTechCare in 2021 as a Research Fellow to work in ForPharmacy project, funded by FCT and Compete2020, a co-promotion project led by the pharmacy-dedicated international IT company Glintt. His work was focused on herb-medicine interactions and antimicrobial resistance survey and prevention as an integrated service in the Portuguese pharmacies. During this period, he won an international mobility exchange grant to do a brief laboratory internship at the Shannon Applied Biotechnology Centre, Technological University of Shannon, Ireland. He was also invited to lecture BSc Nutrition and Dietetics Food Toxicology classes at Polytechnic of Leiria School of Health Sciences, and to write an opinion article for a local newspaper, Diário de Leiria, on the subject of antimicrobial stewardship. In October 2023 he was hired as Research Technician in ciTechCare based CeliAct(TIV) project: “Translocation, Inflammation and Virulence: dissecting mechanisms of gluten-microbiota interactions in Celiac Disease”, funded by Beyond Celiac Foundation. Under CeliAct(TIV) project scope, he is currently doing another international internship, at the Celiac Disease Research Center, University of Tampere, Finland. His research interests are antimicrobial stewardship, herb-drug interactions and Celiac Disease.

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Identification

Personal identification

Full name: Flávio Miguel Pereira Costa

Citation names

Flávio Pereira-Costa
Flávio Costa

Author identifiers

Ciência ID: 5F1E-C8C6-3388
ORCID iD: 0000-0003-1733-8983

Email addresses

flavio.p.costa@ipleiria.pt (Professional)
flaviompc19@gmail.com (Personal)

Telephones

Telephone

(+351) 244845300 (Professional)

Addresses

Rua de Santo André n. 66-68, Campus 5, Politécnico de Leiria, 2410-541, Leiria, Leiria, Portugal (Professional)

Knowledge fields

Natural sciences - Biological Sciences - Biochemistry
Natural sciences - Biological Sciences - Microbiology

Languages

Language	Speaking	Reading	Writing	Listening	Peer-review
Portuguese (Mother tongue)
English	Upper intermediate (B2)	Upper intermediate (B2)	Upper intermediate (B2)	Upper intermediate (B2)	Upper intermediate (B2)

Education

	Degree	Classification
2021/09/15 - 2022/06/30 Concluded	Health Science Research Advanced Course (non-degree course) (Outros) Instituto Politécnico de Leiria Escola Superior de Saúde, Portugal	18 (0-20)
2017 - 2019 Concluded	Biochemistry (Mestrado) Universidade do Porto Faculdade de Ciências, Portugal Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal ""On the role of adenosine-sensitive P1 receptors in human chondrogenesis"" (THESIS/DISSERTATION)	17 (0-20)
2013 - 2017 Concluded	Biochemistry (Licenciatura) Universidade do Porto Faculdade de Ciências, Portugal Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal ""Exploring cyanobacterial genomes for diterpene biosynthesis"" (THESIS/DISSERTATION)	13 (0-20)

Affiliation

Science

	Category Host institution	Employer
2021/09/15 - 2023/09/30	Researcher (Research)	Center for Innovative Care and Health Technology, Portugal
	Center for Innovative Care and Health Technology, Portugal

Teaching in Higher Education

	Category Host institution	Employer
2021/10/18 - 2022/02/26	Invited Assistant (Polytechnic Teacher)	Instituto Politécnico de Leiria Escola Superior de Saúde, Portugal
	Instituto Politécnico de Leiria Escola Superior de Saúde, Portugal

Other Careers

	Category Host institution	Employer
2023/10/02 - Current	Técnico Superior (Técnico Superior)	Instituto Politécnico de Leiria, Portugal
	Center for Innovative Care and Health Technology, Portugal

Others

	Category Host institution	Employer
2021/01/13 - 2021/08/22	Technical Support Assistant	Vodafone Portugal - Comunicações Pessoais S.A., Portugal

2019/12/03 - 2020/08/31	Researcher (Voluntary)	Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
	Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2016/02/01 - 2016/07/31	Extra-Curricular Internship Program (PEEC). Project: Differential Scanning Calorimetry of Membranes - Methodological Study	Universidade do Porto Faculdade de Ciências, Portugal
	Universidade do Porto Faculdade de Ciências, Portugal

Projects

Grant

	Designation	Funders
2021/09/15 - 2023/06/30	ForPharmacy - Future pharmacy as a plug-and-play ecossystem FEDER/070053/12/SI/2020 Research Fellow Center for Innovative Care and Health Technology, Portugal	Agência Nacional de Inovação SA FEDER -Fundo Europeu de Desenvolvimento Regional Concluded

Contract

	Designation	Funders
2023/10/02 - Current	CeliAct(TIV) - Translocation, Inflammation and Virulence: dissecting mechanisms of gluten-microbiota interactions in Celiac Disease 2022 BC EIA Researcher Center for Innovative Care and Health Technology, Portugal	Beyond Celiac Ongoing

Other

	Designation	Funders
2020/07/08 - 2020/12/31	Purinome-rejuvenated autologous STEM cells against COVID-19. Who´s gonna win the ageing battle? 402 Participation in the elaboration, writing and submission of the project. Independent worker. Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal	Associação para a Inovação e Desenvolvimento da FCT Concluded

Outputs

Publications

Conference abstract	Flávio Pereira-Costa; Lages, M.; Braga-Pontes, Cátia; Guarino, MP. "Evidence and risks associated with herb-drug interactions: A Scoping Review". Paper presented in 54th Meeting of the Portuguese Society of Pharmacology, 42nd Meeting of Clinical Pharmacology and 23rd Meeting of Toxicology, Lisbon, 2024.
Conference poster	Flávio Costa; Daniela Cipreste Vaz; Sónia Gonçalves Pereira. "Celiac Disease Related Gut Commensal Bacteria And Its Potential In Degrading Gliadins". Paper presented in 20th International Coeliac Disease Symposium, 2024. Flávio Costa, Ana Roque, Daniela Cipreste Vaz, Sónia Gonçalves Pereira. "Gliadin proteolytic activity from celiac disease related blood and gut commensal bacteria". Paper presented in 10th International Human Microbiome Consortium Congress, 2024.
Journal article	Flávio Pereira-Costa, Sónia Gonçalves Pereira. "Antimicrobial prescription, pharmacodynamics and pharmacokinetics: a review of the Portuguese guidelines applicable to the primary healthcare system". Acta Médica Portuguesa (2024): Under revision Pinto. Cardoso, Rui.; Pereira. Costa, Flavio.; Pedro. Faria, Joao.; Bandarrinha, Patricia.; Bessa. Andres, Catarina.; Correia-de-Sa, Paulo.; Bernardo. Noronha. Matos, José.. "Adenosinergic Signalling In Chondrogenesis And Cartilage Homeostasis: Friend Or Foe?". Biochemical Pharmacology (2019): 113784. http://dx.doi.org/10.1016/j.bcp.2019.113784. Accepted • 10.1016/j.bcp.2019.113784
Newspaper article	Flávio Pereira-Costa. "O bom, o mau e o vilão" da antibioterapia. ("The good, the bad and the ugly" of the antibiotherapy).", Diário de Leiria, 2022
Preprint	Andreia Martins; Flávio Costa; Eva Maia; Isabel Praça; Marlene Lages; Cátia Pontes; Maria Guarino. "Reducing Herb-Drug Interaction Risks: A Clinical Decision Support System for Community Pharmacy (Preprint)". 2023. https://doi.org/10.2196/preprints.47649. 10.2196/preprints.47649

Activities

Oral presentation

	Presentation title	Event name Host (Event location)
2024/05/13	Bactérias comensais de doentes celíacos apresentam diferentes perfis de proteólise de gliadina in vitro	10 anos do Centro de Investigação da Unidade Local de Saúde da Região de Leiria Escola Superior de Saúde de Leiria (Leiria, Portugal)
2022/05/16	Putative therapeutic effect of purinome-rejuvenated mesenchymal STEM cells against airway epithelial cells damage by SARS-CoV-2	EUGLHORIA SEEDING CONFERENCE Lund University (Sweden)
2020/02/06	Adenosine A2A and A2B receptors play differential roles in chondrogenic vs. osteogenic differentiating bone-marrow mesenchymal stromal cells from aged women	SPF 2020 Sociedade Portuguesa de Farmacologia (Coimbra, Portugal)

Event participation

	Activity description Type of event	Event name Institution / Organization
2022/06/01 - 2022/06/01	RUN-EU PLUS Workshops - Researcher Career Development Training Programme 2022 Workshop	Researcher Career Development Training Programme 2022
2021/11/03 - 2021/11/03	Webinar: Bases De Dados E Serviços Para Investigadores (Databases and Services for Researchers) Other	Bases De Dados E Serviços Para Investigadores (Databases and Services for Researchers) Instituto Politécnico de Leiria, Portugal
2021/09/21 - 2021/09/27	Online Course: Introduction to Systematic Reviews and Meta-analyses Other	Introduction to Systematic Reviews and Meta-analyses Johns Hopkins University, United States
2021/09/16 - 2021/09/20	Online Course: Introduction to Systematic Reviews Other	Introduction to Systematic Reviews Stanford University School of Medicine, United States
2020/07/06 - 2020/07/10	EUGLOH Summer School- Biomedical Data Processing and Global Aspects of COVID-19 Other	Szegedi Tudományegyetem, Hungary
2020/02/05 - 2020/02/07	SPF Meeting 2020 Meeting	L Reunião da Sociedade Portuguesa de Farmacologia, XXXVIII Reunião da Farmacologia clínica e XIX Reunião da Toxicologia Universidade de Coimbra, Portugal
2019/02/06 - 2019/02/08	SPF Meeting 2019 Meeting	XLIX Reunião da Sociedade Portuguesa de Farmacologia, XXXVII Reunião da Farmacologia clínica e XVIII Reunião da Toxicologia Universidade do Porto Faculdade de Farmácia, Portugal
2017/03/29 - 2017/03/29	ELSA Conference Conference	Novos desafios ambientais (New environmental challenges) Universidade do Porto Faculdade de Direito, Portugal
2016/03/04 - 2016/03/06	Programa científico na área da Bioquímica (Biochemistry Scientific program) Congress	IV AEICBAS Biomedical Congress Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2016/03/04 - 2016/03/06	Identificação de proteínas por espectometria de massa (Identification of proteins by mass spectrometry) Workshop	IV AEICBAS Biomedical Congress Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2016/03/04 - 2016/03/06	Animações moleculares (Molecular animations) Workshop	IV AEICBAS Biomedical Congress Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2015/03/22 - 2015/03/22	Estudo da atividade de compostos antitumorais (Studying the activity of antitumor compounds) Workshop	III AEICBAS Biomedical Congress Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2015/03/20 - 2015/03/22	Palestras da manhã na área da Bioquímica (Biochemistry morning lectures) Congress	III AEICBAS Biomedical Congress Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2015/03/20 - 2015/03/20	Potencial das cianobactérias como possíveis hospedeiros na síntese de biomoléculas (The potential of cyanobacteria as possible hosts in biomolecule synthesis) Workshop	III AEICBAS Biomedical Congress Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2015/03/07 - 2015/03/07	Conferência realizada por Dr. António Amorim: "Amorim: Uma empresa portuguesa líder no mercado da cortiça" ("Amorim: A leading Portuguese company in the cork market") Conference	Europe vs. Asia: Grass Is Always Greener On The Other Side" Sharing Analisys on Regional Economies - Universidade do Porto Faculdade de Economia, Portugal
2015/02/27 - 2015/02/28	Palestras das II Jornadas de Bioquímica - Indústria vs Investigação (Lectures at the II Biochemistry Conference - Industry vs. Research) Meeting	II Jornadas de Bioquímica - Indústria vs Investigação (II Biochemistry Conference - Industry vs Research) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2015/02/27 - 2015/02/27	Estudo de inibidores de agregação de proteínas - Aplicações terapêuticas (Study of protein aggregation inhibitors - Therapeutic applications) Workshop	II Jornadas de Bioquímica - Indústria vs Investigação (II Biochemistry Conference - Industry vs Research) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Course / Discipline taught

	Academic session	Degree Subject (Type)	Institution / Organization
2021/10/22 - 2022/02/26	Food Toxicology (Theoretical classes)	Dietetics and Nutrition (Licenciatura)	Instituto Politécnico de Leiria Escola Superior de Saúde, Portugal
2020/11/23 - 2020/11/27	Pharmacology I, Pharmacology and Therapeutics I, Preclinical Research and Clinical Trial. Theme: Bone metabolism and osteogenesis: the role of calcium (Practical Classes Collaboration)	Medicine, Veterinary Medicine and Bioengineering (Mestrado integrado)	Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019/12/09 - 2019/12/13	Pharmacology I, Pharmacology and Therapeutics I, Preclinical Research and Clinical Trial. Theme: Bone metabolism and osteogenesis: the role of calcium (Practical Classes Collaboration)	Medicine, Veterinary Medicine and Bioengineering (Mestrado integrado)	Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Scientific expedition

	Activity description	Institution / Organization
2024/04/01 - Current	Visiting researcher - CeliAct(TIV) project	Celiac Disease Research Center (CeliRes) , University of Tampere, Finland
2023/04/24 - 2023/04/28	RUN-EU Short Advanced Programme (SAP) RUN-EU Research Challenge SAP - Delivering on the green transition within the EU (1ECTS)	Széchenyi István Egyetem, Hungary
2022/11/01 - 2022/11/30	RUN-EU International RDI Mobility Programme. Project: Competition assays between yeasts and bacteria: who will win the battle?	Shannon Applied Biotechnology Center (ABC) - Technological University of the Shannon, Ireland

Distinctions

Award

2024	Celiac Association 2024 grant Keliakialiitto, Finland