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She graduated in Clinical analysis in 2015 and afterwards, she pursued in 2017 a master in Molecular Biology and Biomedicine in Universidade Nova de Lisboa. Driven by the passion for science, she completed her PhD in 2023 in Pharmacy in Research Institute for Medicines (iMed.ULisboa)/Faculty of Pharmacy of Universidade de Lisboa. In recent years, she focused on deciphering the potential of the frailty index to better describe phenotypical alterations at advanced age in Multiple Sclerosis, together with the effects of age on CNS pathogenesis and in peripheral immune response, and the effects on the gut-brain axis using the experimental autoimmune encephalomyelitis model. As a junior researcher at i3S - Instituto de Investigação e Inovação em Saúde da Universidade do Porto, she has been focused on understanding the molecular mechanisms that drive Foxn1 expression in thymic epithelial cells. Her commitment to the science is demonstrated by her scientific achievements where she has authored and co-authored 5 scientific papers, 1 book chapter and has participated in more than 10 national and international conferences. She has been distinguished with 5 awards/recognitions and has participated in 3 research projects.
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Identification

Personal identification

Full name
Ana Rita Valente Ribeiro

Citation names

  • Ribeiro, Ana Rita

Author identifiers

Ciência ID
6110-FB6E-ED5E

Email addresses

  • arvribeiro@i3s.up.pt (Professional)
  • aritavribeiro@gmail.com (Personal)

Telephones

Telephone
  • 226074900 (Professional)

Addresses

  • Rua Alfredo Allen 208, 4200-135, Porto, Porto, Portugal (Professional)

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
English Intermediate (B1) Intermediate (B1) Intermediate (B1) Intermediate (B1) Intermediate (B1)
Education
Degree Classification
2018/01/15 - 2023/05/12
Concluded
 Farmácia (Doutoramento)
Major in Biologia Celular e Molecular
Universidade de Lisboa Faculdade de Farmácia, Portugal
"Deciphering the role of aging in Multiple Sclerosis: focusing on frailty index, neuroinflammation and microbiome" (THESIS/DISSERTATION)
 Distinção e Honra
2019/07/17 - 2019/07/31
Attended
 Ciências de Animais de Laboratório (Outros)
Instituto de Medicina Molecular, Portugal
2017
Concluded
 Mestrado em Genética Molecular e Biomedicina (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
"Dissecting deregulated cell-to-cell communication in in vitro Alzheimer’s disease models" (THESIS/DISSERTATION)
 17 valores
2015
Concluded
 Licenciatura em Análises Cínicas e Saúde Pública (Licenciatura)
Universidade Fernando Pessoa, Portugal
"n/a" (THESIS/DISSERTATION)
 17 valores
Affiliation

Science

Category
Host institution 		Employer
2023/07 - Current Contracted Researcher (Research) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2019/10/12 - 2019/12/14 Researcher (Research) Dalhousie University Department of Medicine, Canada
2016/09/01 - 2017/11/20 Research Trainee (Research) Universidade de Lisboa Faculdade de Farmácia, Portugal

Other Careers

Category
Host institution 		Employer
2018/02/01 - 2019/01/05 Assistente (Técnico Superior de Saúde - Laboratório) Laboratório de Análises Clínicas Silva Tavares, Portugal
2014/10/01 - 2015/02/01 Estagiário (3º e 4º Ano) (Técnico Superior de Saúde - Laboratório) Jessa Ziekenhuis Hospital, Belgium
2014/05/01 - 2014/07/01 Estagiário (1º e 2º Ano) (Técnico Superior de Saúde - Laboratório) Hospital-Escola da Universidade Fernando Pessoa, Portugal

Others

Category
Host institution 		Employer
2020/01 - 2023/07 Membro da comissão de estudantes de doutoramento da Faculdade de Farmácia da Universidade de Lisboa Universidade de Lisboa Faculdade de Farmácia, Portugal
Projects

Grant

Designation Funders
2018/01/05 - 2022/01/05 Deciphering the role of neuroinflammation in the psycho-pathology and frailty index of multiple sclerosis
SFRH/BD/138542/2018
PhD Student Fellow

Contract

Designation Funders
2023/07 - Current Molecular Control of Foxn1 Expression in Thymic Epithelial Cells: Advances in Thymus Regenerative Therapies
PTDC/MED-IMU/0888/2021
Researcher
Fundação para a Ciência e a Tecnologia
2019/01/05 - 2023 Targeting multiple sclerosis immune- and psycho-pathophysiology by modulation of neuroinflammation
Merck Serono
PhD Student Fellow
Universidade de Lisboa Faculdade de Farmácia, Portugal

Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
Ongoing
Outputs

Publications

Book chapter
  1. Manish Mishra; Ribeiro, Ana Rita; Howlett, Susan E. "Frailty Indices". In Studying Ageing and Disease in Laboratory Mice, edited by Paul Potter; Ilaria Bellantuono. Elsevier, 2024.
Journal article
  1. Ribeiro, Ana Rita; Catarina Barros; Barateiro, Andreia; Alberro, Ainhoa; Basto, Afonso P.; Luís Graça; Vaz Pinto, Maria; et al. Corresponding author: Adelaide Fernandes, PhD, Faculty of Pharmacy, University of Lisbon. "Age impacts Experimental Autoimmune Encephalomyelitis pathogenesis: focus on S100B temporal Effect". Journal of Neuroinflammation (2024):
    Under revision
  2. Barateiro, Andreia; Barros, Catarina; Pinto, Maria V.; Ribeiro, Ana Rita; Alberro, Ainhoa; Fernandes, Adelaide. "Women in the field of multiple sclerosis: How they contributed to paradigm shifts". Frontiers in Molecular Neuroscience 16 (2023): http://dx.doi.org/10.3389/fnmol.2023.1087745.
    10.3389/fnmol.2023.1087745
  3. Pinto, Maria V.; Santos, Fábio M. F.; Barros, Catarina; Ribeiro, Ana Rita; Pischel, Uwe; Gois, Pedro M. P.; Fernandes, Adelaide. "BASHY Dye Platform Enables the Fluorescence Bioimaging of Myelin Debris Phagocytosis by Microglia during Demyelination". Cells 10 11 (2021): 3163. http://dx.doi.org/10.3390/cells10113163.
    10.3390/cells10113163
  4. Ribeiro, Ana Rita; Barros, Catarina; Barateiro, Andreia; Howlett, Susan E; Fernandes, Adelaide. "Improved Assessment of Overall Health in Variably Aged Murine Models of Multiple Sclerosis With a Novel Frailty Index Tool". The Journals of Gerontology: Series A 77 1 (2021): 1-9. http://dx.doi.org/10.1093/gerona/glab185.
    10.1093/gerona/glab185
  5. Ribeiro, Ana Rita; Howlett, Susan E.; Fernandes, Adelaide. "Frailty—A promising concept to evaluate disease vulnerability". Mechanisms of Ageing and Development 187 (2020): 111217. http://dx.doi.org/10.1016/j.mad.2020.111217.
    Published • 10.1016/j.mad.2020.111217
  6. Ribeiro, Ana. "Secretome from SH-SY5Y APPSwe cells trigger time-dependent CHME3 microglia activation phenotypes, ultimately leading to miR-21 exosome shuttling". Biochimie 155 (2018):
Thesis / Dissertation
  1. "Deciphering the role of aging in Multiple Sclerosis: focusing on frailty index, neuroinflammation and microbiome". PhD, 2023.
  2. Ribeiro, Ana. "Dissecting deregulated cell-to-cell communication in in vitro Alzheimer’s disease models". Master, 2017.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2022/02/09 The impact of age in the glial-immune interplay using the in vivo model of Multiple Sclerosis 52nd Meeting of Portuguese Society of Pharmacology
Instituto de Ciências Biomédicas Abel Salazar (Porto, Portugal)
2022 The impact of age in the in vivo model of Multiple Sclerosis: insights in overall health, spinal cord pathology and gut microbiome 13th iMed.ULisboa Postgraduate Students Meeting
Faculdade de Farmácia da Universidade de Lisboa (Portugal)
2022 Alterations in CNS pathogenesis of the in vivo model of Multiple Sclerosis: age impact VI Symposium of Portuguese Glial Network
i3S (Porto, Portugal)
2021/02/19 Improved Frailty Index scale in in vivo model of Multiple Sclerosis: a novel approach to better understand phenotypic alterations in distinct mice age Reunião da Sociedade Portuguesa de Farmacologia
(Lisboa, Portugal)
2021/02/19 Improved Frailty Index scale in in vivo model of Multiple Sclerosis: a novel approach to better understand phenotypic alterations in distinct mice age Reunião da Sociedade Portuguesa de Farmacologia
(Lisboa, Portugal)
2017/10/12 iPSCs-derived astrocytes from patients with PSEN1¿E9 mutation show a depressed RAGE/miR-155 pathway with impact in extracellular vesicle molecular cargo. 10th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies
(Covilhã, Portugal)
2017/06/30 Dissecting deregulated cell- to-cell communication in an in vitro AD model. 31ª Reunião do Grupo de Estudos do Envelhecimento Cerebral e Demências
(Lisboa, Portugal)
2017/05/25 Relevance of neuron-microglia vesicular trafficking, stress-related microRNAS and DAMPs in Alzheimer's disease XV Meeting of Portuguese Society for Neuroscience
(Braga, Portugal)

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2022 - 2022 13th iMed.ULisboa Meeting (2022 - 2022)
Congress (President of the Organising Committee)
 Universidade de Lisboa Faculdade de Farmácia, Portugal
2021/06/01 - 2021/06/16 iMed.ULisboa Meeting (2021/06/16 - 2021/06/16)
Congress (Member of the Organising Committee)
 Universidade de Lisboa Faculdade de Farmácia, Portugal
2019/05/01 - 2019/05/29 IV Symposium of the Portuguese Glia Network (2019/05/29 - 2019/05/29)
Congress (Member of the Organising Committee)
 Universidade de Lisboa Faculdade de Farmácia, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2021/11/01 - 2022/05/11 Pint of Science
Meeting
 Pint of Science
2022 - 2022 Poster in conference. The influence of age in the pathogenesis of Multiple Sclerosis using an in vivo model
Meeting
 Encontro Ciência
Fundação para a Ciência e a Tecnologia, Portugal
2022 - 2022 Poster in conference. Vamos desmistificar a Esclerose Múltipla?
Meeting
 1ª Jornadas Científicas da Universidade de Lisboa
Universidade de Lisboa, Portugal
2022 - 2022 Poster in conference. . Impact of age in the Central Nervous System pathogenesis of the in vivo model of Multiple Sclerosis
Congress
 Congress of ECTRIMS
2021/11/30 - 2021/11/30 Poster in conference: Understanding glial-immune interplay along age in an in vivo model of Multiple Sclerosis.
Congress
 V Symposium of the Portuguese Glial Network
Universidade de Coimbra, Portugal
2021/10/13 - 2021/10/15 Poster in ECTRIMS 2021: A novel approach to better understand phenotypic alterations in the in vivo model of Multiple Sclerosis at distinct mice age - improved Frailty Index scale
Congress
European Committee for Treatment and Research in Multiple Sclerosis, Switzerland
2021/03/04 - 2021/03/05 Poster in conference: Understanding age-associated changes in immune cell response in an in vivo model of Multiple Sclerosis
Congress
 Symposium on Neuro-Immune Interactions
Harvard University Harvard Stem Cell Institute, United States
2019/07/15 - 2019/07/15 Poster in conference: "Frailty Index in Multiple Sclerosis course: a novel approach to better understand disease outcome."
Congress
 11th iMed.ULisboa Postgraduate Students Meeting and 2nd i3DU Meeting
Universidade de Lisboa Faculdade de Farmácia, Portugal
2017/07/16 - 2017/07/16 Poster in conference: "Dissecting the Effects of Exosomes Derived from Neurons on Microglia Phenotype in an in vitro AD Model using human cell lines"
Congress
 9th iMed.ULisboa Postgraduate Students Meeting and 2nd i3DU Meeting
Universidade de Lisboa Faculdade de Farmácia, Portugal
2017/07/08 - 2017/07/11 Poster in conference: "Role of neuron- microglia secretome and stress-related microRNAS in Alzheimer's disease"
Congress
 XIII European Meeting on Glial Cells in Health and Disease
Edinburgh Napier University - Livingston Campus, United Kingdom

Committee member

Activity description
Role 		Institution / Organization
2019/06/01 - 2023 iMed.ULisboa Postgraduate Students Commission
Member
 Universidade de Lisboa Faculdade de Farmácia, Portugal

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2019/07/01 - 2019/07/27 Theoretical and Practical course on Laboratory Animal Science for Function A, certified by FELASA for Category B. Instituto de Medicina Molecular, Portugal
2019/03/01 - 2019/03/15 Theoretical and Practical course on “Assessment Techniques and Animal Behavior Studies” Instituto de Medicina Molecular, Portugal
Distinctions

Award

2022 Best oral communication winner of the 13th iMed.ULisboa Meeting

Title

2023 PhD in Pharmacy
Universidade de Lisboa, Portugal

Other distinction

2023 Member of the awarded project – “Microbiome manipulation to reduce psychopathology in Multiple Sclerosis
2022 Reward with a free registration to the ECTRIMS congress and a travel grant in the amount of EUR 400
European Committee for Treatment and Research in Multiple Sclerosis, Switzerland
2019 PhD fellow
Fundação para a Ciência e a Tecnologia, Portugal