Personal identification

Full name
Jennifer Scott

Citation names

  • Scott, Jennifer

Author identifiers

Ciência ID
611A-F11D-380F
ORCID iD
0000-0002-6401-962X

Email addresses

  • jenni-scott@outlook.com (Professional)

Languages

Language Speaking Reading Writing Listening Peer-review
English (Mother tongue)
Degree Classification
2017/09 - 2023/07/14
Concluded
 PhD Molecular Biology (Doctor of Philosophy)
The University of Manchester, United Kingdom
"Methionine Synthases as Targets for Antifungal Drug Development" (THESIS/DISSERTATION)
2010/10 - 2014/06
Concluded
 Biology with Professional Placement (Bachelor)
University of Bath, United Kingdom

Science

Category
Host institution 		Employer
2012/08 - 2013/09 Research Assistant (Research) The University of Iowa, United States

Others

Category
Host institution 		Employer
2019/02 - 2024/01 Part-Time Graduate Teaching Assistant The University of Manchester, United Kingdom
2016/05 - 2017/09 Reserch Technician The University of Manchester, United Kingdom
2016 - 2016/04 Freelance Medical Writer/Account Executive Cancer Intelligence Ltd, United Kingdom
2013/10 - 2013/12 Final Year Project Student University of Bath, United Kingdom

Publications

Journal article
  1. Reem Alharthi; Monica Sueiro-Olivares; Isabelle Storer; Hajer Bin Shuraym; Jennifer Scott; Reem Al-Shidhani; Rachael Fortune-Grant; et al. "The sulfur-related metabolic status of Aspergillus fumigatus during infection reveals cytosolic serine hydroxymethyltransferase as a promising antifungal target". Virulence (2025): http://dx.doi.org/10.1080/21505594.2024.2449075.
    10.1080/21505594.2024.2449075
  2. Scott, Jennifer; Amich, Jorge. "The role of methionine synthases in fungal metabolism and virulence". Essays in Biochemistry 67 5 (2023): 853-863. http://dx.doi.org/10.1042/ebc20230007.
    Published • 10.1042/ebc20230007
  3. Jennifer Scott; Clara Valero; Álvaro Mato-López; Ian J. Donaldson; Alejandra Roldán; Harry Chown; Norman Van Rhijn; et al. "Aspergillus fumigatus Can Display Persistence to the Fungicidal Drug Voriconazole". Microbiology Spectrum (2023): https://doi.org/10.1128/spectrum.04770-22.
    10.1128/spectrum.04770-22
  4. "Point Mutation or Overexpression of Aspergillus fumigatus cyp51B, Encoding Lanosterol 14a-Sterol Demethylase, Leads to Triazole Resistance". Antimicrobial Agents and Chemotherapy 65 10 (2021): http://dx.doi.org/10.1128/aac.01252-21.
    10.1128/aac.01252-21
  5. "Fungal and host protein persulfidation are functionally correlated and modulate both virulence and antifungal response". PLOS Biology 19 6 (2021): e3001247-e3001247. http://dx.doi.org/10.1371/journal.pbio.3001247.
    10.1371/journal.pbio.3001247
  6. Jennifer Scott; Monica Sueiro-Olivares; Benjamin P. Thornton; Rebecca A. Owens; Howbeer Muhamadali; Rachael Fortune-Grant; Darren Thomson; et al. "Targeting Methionine Synthase in a Fungal Pathogen Causes a Metabolic Imbalance That Impacts Cell Energetics, Growth, and Virulence". mBio 11 5 (2020): https://doi.org/10.1128/mBio.01985-20.
    10.1128/mBio.01985-20
  7. "Pseudomonas aeruginosa-Derived Volatile Sulfur Compounds Promote Distal Aspergillus fumigatus Growth and a Synergistic Pathogen-Pathogen Interaction That Increases Pathogenicity in Co-infection". Frontiers in Microbiology (2019): http://dx.doi.org/10.3389/fmicb.2019.02311.
    10.3389/fmicb.2019.02311
Preprint
  1. Reem Alharthi; Monica Sueiro-Olivares; Isabelle Storer; Hajer Alshammri; Jennifer Scott; Reem Al-Shidhani; Rachael Fortune-Grant; et al. "The sulfur-related metabolic status ofAspergillus fumigatusduring infection reveals cytosolic serine hydroxymethyltransferase as a promising antifungal target". 2024. https://doi.org/10.1101/2024.03.08.582945.
    10.1101/2024.03.08.582945

Other

Other output
  1. Primary Metabolism of Human Pathogenic Fungi, Importance for Virulence and Potential for Drug Development. 2021. Jennifer Scott; Jorge Amich. https://doi.org/10.1016%2Fb978-0-12-818731-9.00059-8.
    10.1016/b978-0-12-818731-9.00059-8

Oral presentation

Presentation title Event name
Host (Event location)
2022/03 Methionine synthase as a target for antifungal drug development 31st Fungal Genetics Conference
Genetics Society of America (Asilomar, United States)
2019/05 The role of volatile sulphur compounds in Pseudomonas aeruginosa-Aspergillus fumigatus co-infection FEBS Advanced Lecture Course on Human Fungal Pathogens
Federation of European Biochemical Societies (Nice, France)
2019/03 Methionine synthases as targets for antifungal drug development 55th British Society for Medical Mycology Annual Meeting
British Society for Medical Mycology (Birmingham, United Kingdom)

Award

2022 University of Manchester Doctoral Academy Conference Support Grant Award
The University of Manchester, United Kingdom
2022 Fungal Genetics Conference Travel Award
Genetics Society of America, United States
2019 FEBS Youth Travel Fund Grant
Federation of European Biochemical Societies, United Kingdom
2018 BSAC Best Poster Award
The British Society for Antimicrobial Chemotherapy, United Kingdom
2018 Zochonis Special Enterprise Award
The University of Manchester, United Kingdom
2017 The British Society for Antimicrobial Chemotherapy PhD Studentship
The British Society for Antimicrobial Chemotherapy, United Kingdom
2017 8th Advances Against Aspergillosis Scholarship Award
European Confederation of Medical Mycology, Switzerland