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Filipa Alexandra Dias Martins. Completed the Doutoramento in Ciências da Saúde in 2024/11/27 by Universidade Nova de Lisboa, Mestrado in Biologia Molecular e Genética in 2019 by Universidade de Lisboa Faculdade de Ciências and Licenciatura in Bioquímica in 2017 by Universidade de Lisboa Faculdade de Ciências. Published 11 articles in journals. Has 1 section(s) of books. Has 1 patent(s) registered.
Identification

Personal identification

Full name
Filipa Alexandra Dias Martins

Citation names

  • Martins, Filipa

Author identifiers

Ciência ID
6416-6802-4925
ORCID iD
0000-0002-7869-7173

Email addresses

  • filipa.martins@nms.unl.pt (Professional)

Telephones

Mobile phone
  • (+351) 962212514 (Personal)

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Advanced (C1) Proficiency (C2) Upper intermediate (B2) Proficiency (C2) Advanced (C1)
Education
Degree Classification
2020/09/14 - 2024/11/27
Concluded
 Ciências da Saúde (Doutoramento)
Universidade Nova de Lisboa, Portugal
"Targeting glutamine availability – a new strategy to treat malignant gliomas" (THESIS/DISSERTATION)
2017 - 2019
Concluded
 Biologia Molecular e Genética (Mestrado)
Universidade de Lisboa Faculdade de Ciências, Portugal
"Metabolic remodeling of endothelial cells upon hypoxia and ß-blockers as anti-angiogenic drugs (20)" (THESIS/DISSERTATION)
 18
2014 - 2017
Concluded
 Bioquímica (Licenciatura)
Universidade de Lisboa Faculdade de Ciências, Portugal
 15
Outputs

Publications

Book chapter
  1. Lopes-Coelho, Filipa; Martins, Filipa; Serpa, Jacinta. "Endothelial cells (ECs) metabolism: a valuable piece to disentangle cancer biology". edited by Serpa, Jacinta. 2020.
    10.1007/978-3-030-34025-4_8
Conference abstract
  1. Filipa Martins; Céline Gonçalves; Fernanda Silva; David van der Kellen; Eduarda Martins; Marta Pojo; Luís Gonçalves; Bruno Costa; Jacinta Serpa. "Abstract 1770 Targeting glutamine availability with glutaminase 1-based glioblastoma therapy". 2024.
    10.1016/j.jbc.2024.106461
  2. Lopes-Coelho, Filipa; Martins, Filipa; Fernanda Silva; Ana Hipólito; Sofia Gouveia-Fernandes; Germana Domingues; Cindy Mendes; et al. "Novel Mechanisms in Angiogenesis: Oxidative stress as a promoter of monocyte-to-endothelial cell differentiation and endothelial cell activation". Paper presented in SPF Meeting 2021, 2021.
    Accepted
Conference poster
  1. Lopes-Coelho, Filipa; Martins, Filipa; Ana Hipólito; Bernardete F. Melo; Joana Sacramento; Silvia V. Conde; Sofia A. Pereira; Serpa, Jacinta. "Reactive Oxygen Species (ROS) a motor in Endothelial Cells (ECs) activation". Paper presented in ISCaM2019 - 6th Annual meeting, Braga, Portugal, 2019.
Journal article
  1. Cindy Mendes; Isabel Lemos; Ana Hipólito; Bruna Abreu; Catarina Freitas-Dias; Filipa Martins; Rita Pires; et al. "Metabolic profiling and combined therapeutic strategies unveil the cytotoxic potential of selenium-chrysin (SeChry) in NSCLC cells". Bioscience Reports (2024): http://dx.doi.org/10.1042/bsr20240752.
    10.1042/bsr20240752
  2. Catarina Freitas-Dias; Filipe Gonçalves; Filipa Martins; Isabel Lemos; Luís G. Gonçalves; Jacinta Serpa. "Interaction between NSCLC Cells, CD8+ T-Cells and Immune Checkpoint Inhibitors Potentiates Coagulation and Promotes Metabolic Remodeling—New Cues on CAT-VTE". Cells (2024): https://doi.org/10.3390/cells13040305.
    10.3390/cells13040305
  3. Ana Hipólito; Cindy Mendes; Filipa Martins; Isabel Lemos; Inês Francisco; Fernando Cunha; Teresa Almodôvar; et al. "H2S-Synthesizing Enzymes Are Putative Determinants in Lung Cancer Management toward Personalized Medicine". Antioxidants (2023): https://doi.org/10.3390/antiox13010051.
    10.3390/antiox13010051
  4. Filipa Martins; David van der Kellen; Luís G. Gonçalves; Jacinta Serpa. "Metabolic Profiles Point Out Metabolic Pathways Pivotal in Two Glioblastoma (GBM) Cell Lines, U251 and U-87MG". Biomedicines (2023): https://doi.org/10.3390/biomedicines11072041.
    10.3390/biomedicines11072041
  5. Filipa Lopes-Coelho; Filipa Martins; Ana Hipólito; Sílvia V. Conde; Sofia A. Pereira; Luís G. Gonçalves; Jacinta Serpa. "A Metabolic Signature to Monitor Endothelial Cell Differentiation, Activation, and Vascular Organization". Biomedicines (2022): https://doi.org/10.3390/biomedicines10092293.
    10.3390/biomedicines10092293
  6. Filipa Lopes-Coelho; Sofia Nunes; Filipa Martins; Ana Hipólito; Sofia Gouveia-Fernandes; Germana Domingues; Bernardete Melo; et al. "Propranolol therapy for cerebral cavernous malformations". World Academy of Sciences Journal (2022): http://dx.doi.org/10.3892/wasj.2022.158.
    10.3892/wasj.2022.158
  7. Hipólito, Ana; Martins, Filipa; Mendes, Cindy; Lopes-Coelho, Filipa; Serpa, Jacinta. "Molecular and Metabolic Reprogramming: Pulling the Strings Toward Tumor Metastasis". Frontiers in Oncology 11 (2021): http://dx.doi.org/10.3389/fonc.2021.656851.
    Published • 10.3389/fonc.2021.656851
  8. Lopes-Coelho, Filipa; Martins, Filipa; Pereira, Sofia A.; Serpa, Jacinta. "Anti-Angiogenic Therapy: Current Challenges and Future Perspectives". International Journal of Molecular Sciences 22 7 (2021): 3765. http://dx.doi.org/10.3390/ijms22073765.
    10.3390/ijms22073765
  9. Lopes-Coelho, F.; Martins, F.; Hipólito, A.; Mendes, C.; Sequeira, C.O.; Pires, R.F.; Almeida, A.M.; et al. "The Activation of Endothelial Cells Relies on a Ferroptosis-Like Mechanism: Novel Perspectives in Management of Angiogenesis and Cancer Therapy". Frontiers in Oncology 11 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85107046284&partnerID=MN8TOARS.
    10.3389/fonc.2021.656229
  10. Martins, Filipa; Gonçalves, Luís G.; Pojo, Marta; Serpa, Jacinta. "Take Advantage of Glutamine Anaplerosis, the Kernel of the Metabolic Rewiring in Malignant Gliomas". Biomolecules 10 10 (2020): 1370. http://dx.doi.org/10.3390/biom10101370.
    10.3390/biom10101370
  11. Mendes, Cindy; Lopes-Coelho, Filipa; Ramos, Cristiano; Martins, Filipa; Rodrigues, Armanda; Silva, Fernanda; André, Saudade; Serpa, Jacinta. "Unraveling FATP1, regulated by ER-ß, as a targeted breast cancer innovative therapy". Scientific Reports (2019): http://dx.doi.org/10.1038/s41598-019-50531-3.
    10.1038/s41598-019-50531-3

Intellectual property

Patent
  1. Martins, Filipa; Gonçalves, Céline S.; David van der Kellen; Silva, Fernanda; Martins, Eduarda P.; Sofia Gouveia-Fernandes; André, Saudade; et al. 2023. "Glutaminase, Methods and Uses Thereof". Portugal.
    Allowed