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Graduated in Statistics and Operational Research at the Faculty of Sciences of the University of Lisbon (FCUL), in 1995, Lisete Sousa completed her master’s degree in Probability and Statistics at FCUL in 1998. She holds a PhD in Probability and Statistics since 2004. Currently, she is an Associate Professor in the Department of Statistics and Operational Research of FCUL, teaching Statistics Curricular Units in graduate and post-graduate courses. She was the Director of the Master in Biostatistics from September 2009 to January 2017. Lisete Sousa is also a researcher at Centre of Statistics and its Applications (CEAUL), where she was the Director of from January 2017 to December 2022. Currently, she is the Vice-Director of the Centre of Statistics and its Applications and the Vice-President of the Portuguese Statistical Society. Her main research interests are the development of statistical methodologies with application in Molecular Biology, in close collaboration with researchers from the University of Lisbon and other Research Units. In her professional activities interacted with 240 collaborator(s) co-authorship of scientific papers, published 42 articles in journals. and has 2 books chapters.
Identification

Personal identification

Full name
LISETE MARIA RIBEIRO DE SOUSA

Citation names

  • SOUSA, LISETE

Author identifiers

Ciência ID
6518-7145-2F61
ORCID iD
0000-0002-2114-720X
Researcher Id
M-1842-2015
Scopus Author Id
24802739400

Email addresses

  • lmsousa@fc.ul.pt (Professional)

Websites

Knowledge fields

  • Exact Sciences - Mathematics - Statistics and Probability

Languages

Language Speaking Reading Writing Listening Peer-review
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
French Elementary (A2) Intermediate (B1) Beginner (A1) Intermediate (B1)
Spanish; Castilian Intermediate (B1) Upper intermediate (B2) Beginner (A1) Upper intermediate (B2)
German Beginner (A1) Elementary (A2) Beginner (A1) Beginner (A1)
Portuguese Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
Education
Degree Classification
2004/07/23
Concluded
PhD in Probability and Statistics (Doutoramento)
Universidade de Lisboa Faculdade de Ciências, Portugal
"Development of Statistical Methods for the Analysis of Molecular Genetic Data" (THESIS/DISSERTATION)
Aprovada com distinção e louvor ("summa cum laude")
1998/06/17
Concluded
Master in Statistics and Operations Research (Mestrado)
Universidade de Lisboa Faculdade de Ciências, Portugal
"Análise de Sobrevivência: Modelos Alternativos ao Modelo de Cox" (THESIS/DISSERTATION)
Muito Bom (Very Good)
1995/07
Concluded
Degree in Probability and Statistics (Licenciatura)
Universidade de Lisboa Faculdade de Ciências, Portugal
"Análise de Sobrevivência do Cancro do Colo do Útero" (THESIS/DISSERTATION)
16 valores (16 in 20)
Affiliation

Teaching in Higher Education

Category
Host institution
Employer
2015/12/01 - Current Associate Professor (University Teacher) Universidade de Lisboa Faculdade de Ciências, Portugal
2004/06/01 - 2015/12/01 Assistant Professor (University Teacher) Universidade de Lisboa Faculdade de Ciências, Portugal
1997/06/01 - 2004/06/01 Assistant (University Teacher) Universidade de Lisboa Faculdade de Ciências, Portugal
1995/09/01 - 1997/06/01 Assistant (University Teacher) Universidade Lusófona de Humanidades e Tecnologias, Portugal
Projects

Contract

Designation Funders
2023/01/01 - 2024/12/31 Centre of Statistics and its Applications
UIDB/00006/2020
Co-Principal Investigator (Co-PI)
FCiênciasID Associação para a Investigação e Desenvolvimento de Ciências, Portugal

Universidade de Lisboa Centro de Estatística e Aplicações, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2021/01/01 - 2024/03/31 EMOTION - authEntic cheesoMics: from big data, through labOratory, towards the fuTure of protected designation of OrigiN
PTDC/OCE-ETA/1785/2020
Researcher
Fundação para a Ciência e a Tecnologia
Ongoing
2020/01/01 - 2022/12/31 FCT Strategic project - UIDB/00006/2020
UIDB/00006/2020
Principal investigator
Ongoing
2019 - 2022 Gene-Environment Interaction in Autism Spectrum Disorder - PTDC/MED-OUT/28937/2017
PTDC/MED-OUT/28937/2017
Researcher
Concluded
2019/01 - 2019/12 FCT Strategic project - UID/MAT/00006/2019
UID/MAT/00006/2019
Principal investigator
Concluded
2016/01 - 2018/12 SMiLax: Semantic Mining with Linked Data
Researcher
Stichting Weten
2015/01 - 2018/12 FCT Strategic project: UID/MAT/00006/2013
UID/MAT/00006/2013
Researcher
2012/01 - 2014/12 Statistical Methods in Environmental and Epidemiological Processes
Researcher
Stichting Weten
2011/01/01 - 2013/12/31 Projecto Estratégico - UI 6 - 2011-2012
PEst-OE/MAT/UI0006/2011
Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2007/09 - 2010/12 Statistical Methods in Genetics and Environment
Researcher
Stichting Weten
2010 - 2010 Micorrhizal Symbiosis: SOBREIRO/0034/2009 (Cork Oak ESTs Consortium (COEC))
SOBREIRO/0034/2009
Other
Concluded

Other

Designation Funders
2019 - 2022 Project IPMA "Small Fishing on the Portuguese West Coast PP-Centro". Awarded to CEAUL.
PP Centro
Principal investigator
Ongoing
Outputs

Publications

Book
  1. FRAGA ALVES, Maria Isabel; Gomes, Maria Ivette; SOUSA, LISETE. Fundamentos e Metodologias da Estatística. Centro de Estatística e Aplicações. 2007.
    Published
Book chapter
  1. Carina Silva; Maria Antónia Amaral Turkman; Lisete Sousa. "Impact of OVL Variation on AUC Bias Estimated by Non-parametric Methods". 173-184. Springer International Publishing, 2020.
    10.1007/978-3-030-58808-3_14
  2. Silva, Carina; Freitas, Adelaide; Roque, Sara. "Arrow Plot and Correspondence Analysis Maps for Visualizing the Effects of Background Correction and Normalization Methods on Microarray Data". In Pattern Recognition in Computational Molecular Biology, 394-416. John Wiley & Sons, Inc, 2016.
    Published • 10.1002/9781119078845.ch21
Conference abstract
  1. Marques-Vieira, Cristina; Sousa, Luís; Costa, Débora; Mendes, Cláudia; Sousa, Lisete (6518-7145-2F61); Caldeira, Sílvia. "Validation of the nursing diagnosis risk for falls in elderly". 2018.
    Published • 10.1186/s12913-018-3444-8
Conference paper
  1. Fortes, C.S.; Freitas, A.; Roque, S.; Sousa, L.. "Arrow plot and CA maps on microarray prepossessing methods". 2014.
    10.1109/ICCSA.2014.52
  2. Amaral, Margarida; Clarke, Luka A; Roxo Rosa, Mónica; SOUSA, LISETE. "Genomic and Proteomics approaches to study the genetic disease Cystic Fibrosis.". Paper presented in Proceedings of the Workshop on Statistics in Genomics and Proteomics., Estoril, 2006.
    Published
Conference poster
  1. Nuno Domingues; SOUSA, LISETE; Laureano, Gonçalo; Figueiredo, Andreia; Maia, Marisa. "Application of Statistical Methodologies as a Contribute to Define Disease Control Strategies for a Sustainable Viticulture". Paper presented in XXVI Congresso da Sociedade Portuguesa de Estat´istica, 2023.
  2. Pinto, Vera; Correia, I. J. F.; Marques, Carolina; Marques, Tiago Andre; SOUSA, LISETE. "The role of Statistics in Science and Society: CEAUL's contributions". Paper presented in Ciências Research Day, 2022.
  3. Martins, R.; SOUSA, LISETE. "Modelling the population dynamics of the Blackspot Seabream (Pagellus Bogaraveo) on the Portuguese coast". Paper presented in 36th International Workshop on Statistical Modelling, 2022.
  4. Pestana, Carolina; SOUSA, LISETE; Cristina João. Corresponding author: Cristina João. "Study of biomarkers in Multiple Myeloma: a statistical approach for longitudinal assessment of extracellular vesicles and its prognostic value". Paper presented in 5.ª Conferência Anual da redeSAÚDE, 2021.
  5. Carolina Pestna; SOUSA, LISETE; Emilie Carneiro; Ana Filipa Barahona; Joana Caetano; Ana Raquel lopes; Bruna Ferreira; Cristina João. "Statistical methods for the study of extracellular vesicles content and their potential as biomarkers of multiple myeloma aggressivenesshttps://proa.ua.pt/index.php/jshd/article/view/19953/15330". Paper presented in 2nd Statistics on Health Decision Making (SHDM): clinical trials, 2020.
Edited book
  1. Scotto, M, Sousa L, de Zea Bermudez, Patrícia. Symposium on Big Data in Finance Retail and Commerce: Statistical and Computational Challenges- Book of Abstracts. Lisboa: CEAUL. 2017.
    Published • Editor
  2. Antunes, M., Andreozzi, V., Sousa, L. e Gonçalves, L. StaM2010: Statistical Modelling: Challenges in Health, Programme and Book of Abstracts.. Lisboa, Portugal: CEAUL. 2010.
    Published • Editor
  3. SOUSA, LISETE; Gonçalves, Luzia. Workshop on Statistics in Genomics an Proteomics: Programme and Book of Abstracts.. Lisboa, Portugal: CEAUL. 2005.
    Published • Editor
Journal article
  1. Watanabe, Ligia Moriguchi; Sousa, Lisete; Noronha, Natália; Pinhel, Marcela; Carvalho, Gleyson; Rodrigues, Guilherme; Couto, Francisco; et al. "Genome-wide case-control association study identifies a locus connecting NRF2-ARE regulation and selenium deficiency". Free Radical Biology and Medicine 208 (2023): S23-S24. http://dx.doi.org/10.1016/j.freeradbiomed.2023.10.054.
    Published • 10.1016/j.freeradbiomed.2023.10.054
  2. João Xavier Santos; Pedro Sampaio; Célia Rasga; Hugo Martiniano; Clarissa Faria; Cátia Café; Alexandra Oliveira; et al. "Evidence for an association of prenatal exposure to particulate matter with clinical severity of Autism Spectrum Disorder". Environmental Research (2023): https://doi.org/10.1016/j.envres.2023.115795.
    10.1016/j.envres.2023.115795
  3. Joana Figueiredo; Rita B. Santos; Leonor Guerra-Guimarães; Céline C. Leclercq; Jenny Renaut; Lisete Sousa; Andreia Figueiredo. "Deep into the Apoplast: Grapevine and Plasmopara viticola Proteomes Reveal the Secret Beneath Host and Pathogen Communication at 6 h After Contact". Phytopathology® (2023): https://doi.org/10.1094/PHYTO-09-22-0340-FI.
    10.1094/PHYTO-09-22-0340-FI
  4. Vanessa Azevedo; Loretta Daddiego; Maria Francesca Cardone; Giorgio Perrella; Lisete Sousa; Rita B. Santos; Rui Malhó; et al. "Transcriptomic and methylation analysis of susceptible and tolerant grapevine genotypes following Plasmopara viticola infection". Physiologia Plantarum 174 5 (2022): http://dx.doi.org/10.1111/ppl.13771.
    10.1111/ppl.13771
  5. Santos, J.X.; Rasga, C.; Marques, A.R.; Martiniano, H.; Asif, M.; Vilela, J.; Oliveira, G.; et al. "A Role for Gene-Environment Interactions in Autism Spectrum Disorder Is Supported by Variants in Genes Regulating the Effects of Exposure to Xenobiotics". Frontiers in Neuroscience 16 (2022): http://www.scopus.com/inward/record.url?eid=2-s2.0-85131742759&partnerID=MN8TOARS.
    10.3389/fnins.2022.862315
  6. Maria João Heitor; Alexandra Dinis; SOUSA, LISETE; Sérgio Moreira; Joana Carreiras; Sara Ambrósio; Carry Cooper; José Pereira Miguel. "Psychosocial Determinants of Presenteeism at the Workplace in the Pre - COVID-19 Era in A Southern European Country - The Mediating Role of Mental Health and Wellbeing". Journal of Psychiatry and Behavioral Sciences 4 1 (2021): 1056. https://meddocsonline.org/journal-of-psychiatry-and-behavioral-sciences/psychosocial-determinants-of-presenteeism-at-the.pdf.
    Open access • Published
  7. M. Sebastiana; A. Gargallo-Garriga; J. Sardans; M. Pérez-Trujillo; F. Monteiro; A. Figueiredo; M. Maia; et al. "Metabolomics and transcriptomics to decipher molecular mechanisms underlying ectomycorrhizal root colonization of an oak tree". Scientific Reports 11 1 (2021): https://doi.org/10.1038%2Fs41598-021-87886-5.
    10.1038/s41598-021-87886-5
  8. Luzia Gonçalves; Maria Antónia Amaral Turkman; Carlos Geraldes; Tiago A. Marques; Lisete Sousa. "COVID-19: Nothing is Normal in this Pandemic". Journal of Epidemiology and Global Health (2021): https://doi.org/10.2991%2Fjegh.k.210108.001.
    10.2991/jegh.k.210108.001
  9. Chiango, H.; Figueiredo, A.; Sousa, L.; Sinclair, T.; da Silva, J.M.. "Assessing drought tolerance of traditional maize genotypes of Mozambique using chlorophyll fluorescence parameters". South African Journal of Botany 138 (2021): 311-317. http://www.scopus.com/inward/record.url?eid=2-s2.0-85099795143&partnerID=MN8TOARS.
    10.1016/j.sajb.2021.01.005
  10. Cristina Maria Alves Marques-Vieira; Luís Manuel Mota de Sousa; Cristina Rosa Soares Lavareda Baixinho; Maria Gorete Mendonça dos Reis; Francisco Javier Pérez-Rivas; Lisete Maria Ribeiro de Sousa. "VALIDATION OF THE INTERNATIONAL 7-ITEM FALLS EFFICACY SCALE IN PORTUGUESE COMMUNITY-DWELLING OLDER ADULTS". Texto & Contexto - Enfermagem (2021): https://doi.org/10.1590/1980-265x-tce-2019-0243.
    10.1590/1980-265x-tce-2019-0243
  11. Pestana, Carolina; SOUSA, LISETE; Arnault Carneiro, Emilie; Barahona, AF; Caetano, Joana; Lopes, Raquel (A71E-87C5-1CC5; Velosa Ferreira, Bruna; Cristina João. "Statistical methods for the study of extracellular vesicles content and their potential as biomarkers of multiple myeloma aggressiveness". Journal of Statistics on Health Decision 2 2 (2020): https://doi.org/10.34624/jshd.v2i2.19953.
    Published • 10.34624/jshd.v2i2.19953
  12. Wetzel-Gastal, D.; Feitor, F.; van Harten, S.; Sebastiana, M.; Sousa, L.M.R.; Cardoso, L.A.. "A genomic study on mammary gland acclimatization to tropical environment in the Holstein cattle". Tropical Animal Health and Production 50 1 (2018): 187-195. http://www.scopus.com/inward/record.url?eid=2-s2.0-85030095043&partnerID=MN8TOARS.
    10.1007/s11250-017-1420-7
  13. Marques-Vieira, C.M.A.; Sousa, L.M.M.; Sousa, L.M.R.; Berenguer, S.M.A.C.. "Validation of the Falls Efficacy Scale - International in a sample of Portuguese elderly". Revista brasileira de enfermagem 71 2 (2018): 747-754. http://www.scopus.com/inward/record.url?eid=2-s2.0-85054104445&partnerID=MN8TOARS.
    10.1590/0034-7167-2017-0497
  14. Carteiro, Dora (3419-2CCE-9220); Caldeira, Sílvia; Sousa, Lisete (6518-7145-2F61); Costa, Débora; Mendes, Cláudia. "Clinical Validation of the Nursing Diagnosis of Sexual Dysfunction in Pregnant Women". International Journal of Nursing Knowledge 28 4 (2017): 219-224. http://www.scopus.com/inward/record.url?eid=2-s2.0-84963682783&partnerID=MN8TOARS.
    Published • 10.1111/2047-3095.12139
  15. Cristina Maria Alves Marques-Vieira; Luís Manuel Mota Sousa; Sandy Severino; Lisete Sousa; Sílvia Caldeira. "Cross-cultural validation of the falls efficacy scale international in elderly: Systematic literature review". Journal of Clinical Gerontology and Geriatrics 7 3 (2016): 72-76. http://dx.doi.org/10.1016/j.jcgg.2015.12.002.
    10.1016/j.jcgg.2015.12.002
  16. Carteiro, D.M.; de Sousa, L.M.; Caldeira, S.M.. "Clinical indicators of sexual dysfunction in pregnant women: integrative literature review". Revista brasileira de enfermagem 69 1 (2016): 153-161. http://www.scopus.com/inward/record.url?eid=2-s2.0-85011839269&partnerID=MN8TOARS.
    10.1590/0034-7167.2016690122i
  17. Marques-Vieira, C.M.A.; de Sousa, L.M.M.; de Sousa, L.M.R.; Berenger, S.M.A.C.. "The nursing diagnosis ‘impaired walking’ in elderly: Systematic literature review,O diagnóstico de enfermagem ‘andar comprometido’ nos idosos: Revisão sistemática da literatura,O diagnóstico de enfermería ‘deterioro de la deambulación’ en ancianos: Revisión sistemática de la literatura". Texto e Contexto Enfermagem 25 3 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84989311555&partnerID=MN8TOARS.
    10.1590/0104-07072016003350015
  18. Wetzel-Gastal, D.; Feitor, F.; van Harten, S.; Sebastiana, M.; Sousa, L.M.R.; Cardoso, L.A.. "Genomic study of the mammary gland in bovines acclimated to a tropical environment". South African Journal of Animal Sciences 46 1 (2016): 1-13. http://www.scopus.com/inward/record.url?eid=2-s2.0-84958668901&partnerID=MN8TOARS.
    10.4314/sajas.v46i1.1
  19. Bastos, H.P.; Sousa, L.; Clarke, L.A.; Couto, F.M.. "Functional coherence metrics in protein families". Journal of Biomedical Semantics 7 1 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84978134269&partnerID=MN8TOARS.
    10.1186/s13326-016-0076-y
  20. Vanessa Tolentino Pereira; Lisete Sousa; António Teixeira de Sousa; Maria Salomé Pais. "Mechanisms of resistance/tolerance of Pyrus communis to Stemphylium vesicarium. A transcriptome analysis". Agroforest Syst (2015): http://dx.doi.org/10.1007/s10457-015-9831-9.
    10.1007/s10457-015-9831-9
  21. Luka A. Clarke; Hugo M. Botelho; Lisete Sousa; Andre O. Falcao; Margarida D. Amaral. "Transcriptome meta-analysis reveals common differential and global gene expression profiles in cystic fibrosis and other respiratory disorders and identifies CFTR regulators". Genomics (2015): http://dx.doi.org/10.1016/j.ygeno.2015.07.005.
    10.1016/j.ygeno.2015.07.005
  22. Agudelo-Romero P; Erban A; Rego C; Carbonell-Bejerano P; Nascimento T; Sousa L; Martínez-Zapater JM; Kopka J; Fortes AM. "Transcriptome and metabolome reprogramming in Vitis vinifera cv. Trincadeira berries upon infection with Botrytis cinerea.". (2015): http://europepmc.org/abstract/med/25675955.
    10.1093/jxb/eru517
  23. Bastos HP; Sousa L; Clarke LA; Couto FM. "GRYFUN: A Web Application for GO Term Annotation Visualization and Analysis in Protein Sets.". (2015): http://europepmc.org/abstract/med/25794277.
    10.1371/journal.pone.0119631
  24. Rial, T; Sousa, Lisete (6518-7145-2F61); García, E; Pinsach, P. "Efectos agudos de una sesión de técnicas hipopresivas en diferentes parámetros corporales.". Cuestiones de Fisioterapia – Revista Universitária de Informacíon e Investigacíon en Fisioterapia 43 1 (2014): 13-21. https://dialnet.unirioja.es/servlet/articulo?codigo=4573217.
    Published
  25. Sebastiana, M.; Vieira, B.; Lino-Neto, T.; Monteiro, F.; Figueiredo, A.; Sousa, L.; Pais, M.S.; Tavares, R.; Paulo, O.S.. "Oak root response to ectomycorrhizal symbiosis establishment: RNA-seq derived transcript identification and expression profiling". PLoS ONE 9 5 (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84901444345&partnerID=MN8TOARS.
    10.1371/journal.pone.0098376
  26. Agudelo-Romero, P.; Ali, K.; Choi, Y.H.; Sousa, L.; Verpoorte, R.; Tiburcio, A.F.; Fortes, A.M.. "Perturbation of polyamine catabolism affects grape ripening of Vitis vinifera cv. Trincadeira". Plant Physiology and Biochemistry 74 (2014): 141-155. http://www.scopus.com/inward/record.url?eid=2-s2.0-84888785730&partnerID=MN8TOARS.
    10.1016/j.plaphy.2013.11.002
  27. Clarke, Luca; Amaral, Margarida. "WS20.3 Transcriptomics of native nasal epithelium expressing F508del-CFTR and intersecting data from comparable studies". Journal of Cystic Fibrosis (2013): http://www.cysticfibrosisjournal.com/article/S1569-1993(13)60125-3/pdf.
    DOI:10.1016/S1569-1993(13)60125-3
  28. Agudelo-Romero, P.; Erban, A.; Sousa, L.; Pais, M.S.; Kopka, J.; Fortes, A.M.. "Search for Transcriptional and Metabolic Markers of Grape Pre-Ripening and Ripening and Insights into Specific Aroma Development in Three Portuguese Cultivars". PLoS ONE 8 4 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84875670721&partnerID=MN8TOARS.
    10.1371/journal.pone.0060422
  29. Clarke, L.A.; Sousa, L.; Barreto, C.; Amaral, M.D.. "Changes in transcriptome of native nasal epithelium expressing F508del-CFTR and intersecting data from comparable studies". Respiratory Research 14 1 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84875327356&partnerID=MN8TOARS.
    10.1186/1465-9921-14-38
  30. Monteiro, F.; Sebastiana, M.; Figueiredo, A.; Sousa, L.; Cotrim, H.C.; Pais, M.S.. "Labellum transcriptome reveals alkene biosynthetic genes involved in orchid sexual deception and pollination-induced senescence". Functional and Integrative Genomics 12 4 (2012): 693-703. http://www.scopus.com/inward/record.url?eid=2-s2.0-84877040702&partnerID=MN8TOARS.
    10.1007/s10142-012-0288-x
  31. Sousa, M.; Servidoni, M.F.; Vinagre, A.M.; Ramalho, A.S.; Bonadia, L.C.; Felício, V.; Ribeiro, M.A.; et al. "Measurements of CFTR-Mediated Cl- Secretion in Human Rectal Biopsies Constitute a Robust Biomarker for Cystic Fibrosis Diagnosis and Prognosis". PLoS ONE 7 10 (2012): http://www.scopus.com/inward/record.url?eid=2-s2.0-84867641604&partnerID=MN8TOARS.
    10.1371/journal.pone.0047708
  32. Silva-Fortes, C.; Amaral Turkman, M.A.; Sousa, L.. "Arrow plot: A new graphical tool for selecting up and down regulated genes and genes differentially expressed on sample subgroups". BMC Bioinformatics 13 1 (2012): http://www.scopus.com/inward/record.url?eid=2-s2.0-84862693300&partnerID=MN8TOARS.
    10.1186/1471-2105-13-147
  33. Figueiredo, A.; Monteiro, F.; Fortes, A.M.; Bonow-Rex, M.; Zyprian, E.; Sousa, L.; Pais, M.S.. "Cultivar-specific kinetics of gene induction during downy mildew early infection in grapevine". Functional and Integrative Genomics 12 2 (2012): 379-386. http://www.scopus.com/inward/record.url?eid=2-s2.0-84864692857&partnerID=MN8TOARS.
    10.1007/s10142-012-0261-8
  34. Sampaio, P.N.; Sousa, L.; Calado, C.R.C.; Pais, M.S.; Fonseca, L.P.. "Use of chemometrics in the selection of a Saccharomyces cerevisiae expression system for recombinant cyprosin B production". Biotechnology Letters 33 11 (2011): 2111-2119. http://www.scopus.com/inward/record.url?eid=2-s2.0-80053207520&partnerID=MN8TOARS.
    10.1007/s10529-011-0678-5
  35. Barreto-Hernadez, E.; Gama-Carvalho, M.; Sousa, L.. "Pre-processing optimization of RNA immunoprecipitation microarray data". Journal of Computational Biology 18 10 (2011): 1319-1328. http://www.scopus.com/inward/record.url?eid=2-s2.0-80053123169&partnerID=MN8TOARS.
    10.1089/cmb.2010.0020
  36. Fortes, A.M.; Agudelo-Romero, P.; Silva, M.S.; Ali, K.; Sousa, L.; Maltese, F.; Choi, Y.H.; et al. "Transcript and metabolite analysis in Trincadeira cultivar reveals novel information regarding the dynamics of grape ripening". BMC Plant Biology 11 (2011): http://www.scopus.com/inward/record.url?eid=2-s2.0-80055110827&partnerID=MN8TOARS.
    10.1186/1471-2229-11-149
  37. Sampaio, P.N.; Calado, C.R.C.; Sousa, L.; Bressler, D.C.; Pais, M.S.; Fonseca, L.P.. "Optimization of the culture medium composition using response surface methodology for new recombinant cyprosin B production in bioreactor for cheese production". European Food Research and Technology 231 2 (2010): 339-346. http://www.scopus.com/inward/record.url?eid=2-s2.0-77952421650&partnerID=MN8TOARS.
    10.1007/s00217-010-1281-z
  38. Sebastiana, M.; Figueiredo, A.; Acioli, B.; Sousa, L.; Pessoa, F.; Baldé, A.; Pais, M.S.. "Identification of plant genes involved on the initial contact between ectomycorrhizal symbionts (Castanea sativa - European chestnut and Pisolithus tinctorius)". European Journal of Soil Biology 45 3 (2009): 275-282. http://www.scopus.com/inward/record.url?eid=2-s2.0-67349227129&partnerID=MN8TOARS.
    10.1016/j.ejsobi.2009.02.001
  39. Acioli-Santos, B.; Sebastiana, M.; Pessoa, F.; Sousa, L.; Figueiredo, A.; Fortes, A.M.; Baldé, A.; Maia, L.C.; Pais, M.S.. "Fungal transcript pattern during the preinfection stage (12 h) of ectomycorrhiza formed between Pisolithus tinctorius and Castanea sativa roots, identified using cDNA microarrays". Current Microbiology 57 6 (2008): 620-625. http://www.scopus.com/inward/record.url?eid=2-s2.0-56949091950&partnerID=MN8TOARS.
    10.1007/s00284-008-9253-2
  40. Antunes, M.; Sousa, L.. "Bayesian classification and non-Bayesian label estimation via EM algorithm to identify differentially expressed genes: A comparative study". Biometrical Journal 50 5 (2008): 824-836. http://www.scopus.com/inward/record.url?eid=2-s2.0-54549097119&partnerID=MN8TOARS.
    10.1002/bimj.200710468
  41. Fortes, A.M.; Santos, F.; Choi, Y.H.; Silva, M.S.; Figueiredo, A.; Sousa, L.; Pessoa, F.; et al. "Organogenic nodule development in hop (Humulus lupulus L.): Transcript and metabolic responses". BMC Genomics 9 (2008): http://www.scopus.com/inward/record.url?eid=2-s2.0-54949090034&partnerID=MN8TOARS.
    10.1186/1471-2164-9-445
  42. Figueiredo, A.; Fortes, A.M.; Ferreira, S.; Sebastiana, M.; Choi, Y.H.; Sousa, L.; Acioli-Santos, B.; et al. "Transcriptional and metabolic profiling of grape (Vitis vinifera L.) leaves unravel possible innate resistance against pathogenic fungi". Journal of Experimental Botany 59 12 (2008): 3371-3381. http://www.scopus.com/inward/record.url?eid=2-s2.0-51749103583&partnerID=MN8TOARS.
    10.1093/jxb/ern187
Journal issue
  1. Giovani Silva; Sousa, Lisete (6518-7145-2F61); Sousa, Inês; Roca Pardiñas. "REVSTAT - Special Issue on Biometry". REVSTAT 17 2 (2019): https://www.ine.pt/revstat/tables.html.
    Published • Coeditor
  2. Sousa, Lisete (6518-7145-2F61); Andreozzi, Valeska; Marilia Antunes; Gonçalves, Luzia. "Statistical Modelling: Challenges in Health - REVSTAT Special Edition". REVSTAT (2011):
    Published • Coeditor
Magazine article
  1. Alpuim, Teresa; SOUSA, LISETE. "Estatística, uma Vacina para Proteger a Democracia e Combater o Vírus da Desinformação", Revista Pontos de Vista, 2022, https://issuu.com/revistapontosdevista/docs/revista_pontos_de_vista_edi_o_106/74..
Newspaper article
  1. SOUSA, LISETE; Marques, Tiago Andre; Amaral Turkman, M.A.. "Não se deixe iludir pelas aparências. Não é tão simples como parece (Don't be deceived by appearances. It's not as simple as it seems.)", Observador, 2020, https://observador.pt/opiniao/nao-se-deixe-iludir-pelas-aparencias-nao-e-tao-simples-como-parece/.
Online resource
  1. Monteiro, Filipa; Sebastiana, Mónica; Figueiredo, Andreia; SOUSA, LISETE; Cotrim, HC; Pais, M. Salomé. NCBI's Gene Expression Omnibus: GEO accession number GSE28273. 2011.. 2011. http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE28273.
  2. Monteiro, Filipa; Sebastiana, Mónica; Figueiredo, Andreia; SOUSA, LISETE; Cotrim, HC; Pais, M. Salomé. NCBI GenBank Nucleotide, accession numbers: HO849876- HO850144 (269 ESTs sequences of Ophrys fusca). 2010. https://www.ncbi.nlm.nih.gov/nuccore/HO850144.
Report
  1. Correia, Iúri J. F.; SOUSA, LISETE; Farias, Inês; Figueiredo, Ivone. 2021. Demographic analysis of Pagellus bogaraveo population in Portuguese continental waters. https://www.ices.dk/sites/pub/Publication%20Reports/Forms/DispForm.aspx?ID=37682.
  2. Santos, Mário; Sousa, Lisete; Turkman, Maria Antónia Amaral; Urfer, Wolfgang;. 2002. Hidden Markov Models and Neural Networks: Identifying Signal Peptides and Transmembrane Protein Topology. http://dx.doi.org/10.17877/DE290R-14172.
    10.17877/DE290R-14172
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2024/02/06 The Impact of Multiple Simultaneous Testing in Omics Studies DSABNS - 15th Conference on Dynamical Systems Applied to Biology and Natural Sciences
NOVA FCT, NOVA University (LIsbon, Portugal)
2019/02/18 Modelação Ecológica? Eu, é mais Genética: Preciso de Modelos, e sem Estatística não vou lá! Modelação Ecológica (Ecological Modelling)
Faculty of Sciences, Lisbon University (Lisboa, Portugal)

Supervision

Thesis Title
Role
Degree Subject (Type)
Institution / Organization
2023 - 2023 Finding Biomarkers of Metastatic Potential in Colorectal Cancer
Co-supervisor
Bioinformatics and Computational Biology (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
2021 - 2021/07 Modelo Aditivo Generalizado com função baseada num Perceptrão Multicamada: Estimação da função razão de possibilidades e respectivo intervalo de confiança (Generalized Additive Model with a function based on a Multilayer Perceptron: Estimation of the odds ratio function and respective confidence interval)
Co-supervisor
Biostatístics (Master)
Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal
2021 - 2021/06 Study of biomarkers in Multiple Myeloma: a statistical approach for longitudinal assessment of extracellular vesicles and its prognostic value
Supervisor
Biostatístics (Master)
Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal
2021 - 2021 Comparative analysis of non-linear models with parametric link function based on the family of Czado functions and asymmetric functions of Aranda Ordaz
Co-supervisor
Biostatístics (Master)
Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal
2020 - 2020/09 Obesity Genetic Risk Score
Supervisor of Catarina Ribeiro
Biostatístics (Master)
Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal
2020 - 2020/07 Análise estatística de dados de metabolómica: identificação dos compostos envolvidos na resposta das plantas à simbiose com fungos ectomicorrízicos (Statistical analysis of metabolomics data: identification of compounds involved in the response of plants to symbiosis with ectomycorrhizal fungi)
Supervisor of Bruno Bento
Biostatístics (Master)
Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal
2019 - 2019/07 Métodos paramétricos de screening em classificação supervisionada na presença de populações assimétricas (Parametric screening methods in supervised classification in the presence of asymmetric populations)
Co-supervisor of Ana Sofia Soares
Statistics and Operations Research - Probability and Statistics (PhD)
Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal
2019 - 2019 Dynamic prediction of a long-term survival in patients with early-stage breast cancer
Supervisor
Biostatístics (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
2019 - 2019 Resilience: statistical study of psychosocial and biological predictors at the workplace
Supervisor
Biostatístics (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
2018 - 2018 Implementation of an hybrid machine learning methodology for pharmacological modeling
Co-supervisor
Bioinformatics a Computational Biology (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
2017 - 2017 Splicing kinetics revealed by nascent transcript sequencing Bioinformática e Biologia Computacional (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
2017 - 2017 Online behavorial patterns in a health crisis setting: the 2009 pandemic Bioinformática e Biologia Computacional (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
2017 - 2017 Analysis of gene expression in adipocytes of individuals with metabolic syndrome by multivariate statistical methods
Supervisor
Bioestatística (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
2014 - 2017 Validação do diagnóstico de enfermagem impaired walking (00088) em idosos
Co-supervisor
IX Doutoramento em Enfermagem (PhD)
Universidade Católica Portuguesa, Portugal
2016 - 2016 Análise por prospeção de dados de registos eletrónicos de saúde de pacientes com cancro do pulmão Gestão de Informação (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
2016 - 2016 Analysis of the contribution of alternative splicing glioma subtype definition Bioinformática e Biologia Computacional (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
2016 - 2016 Post - transcriptional circadian gene expression regulation in trypanosoma brucei Bioinformática e Biologia Computacional (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
2014 - 2016 Validação do diagnóstico de enfermagem disfunção sexual (00059) em grávidas
Co-supervisor
IX Doutoramento em Enfermagem (PhD)
Universidade Católica Portuguesa, Portugal
2015 - 2015 LincRNA profile in clear cell renal cell carcinoma using RNA-seq data Bioinformática e Biologia Computacional (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
2015 - 2015 LINCRNAS´ profile in setd2 downregulated cells Bioinformática e Biologia Computacional (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
2014 - 2014 Intragenic initiation in SETD2 deficient cells Bioestatística (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
2014 - 2014 Genome-wide profiling of RNA polymerase II and associated co-transcriptional processes using advanced NET-seq data Bioinformática e Biologia Computacional (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
2013 - 2013 Study of the role of SETD2 mutations in clear cell renal cell carninoma (ccRCC) Bioestatística (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
2006 - 2012 Aplicação da Metodologia Roc na Análise de Dados de Microarrays Estatística e Investigação Operacional (PhD)
Universidade de Lisboa, Portugal
2009 - 2011 Metodologias de classificação supervisionada para análise de dados de microarrays
Supervisor
Estatística e Investigação Operacional (PhD)
Universidade de Lisboa, Portugal
2005 - 2011 Statistical methodologies for the analysis and normalization of rip-chip data.
Supervisor
Estatística e Investigação Operacional (PhD)
Universidade de Lisboa, Portugal

Event organisation

Event name
Type of event (Role)
Institution / Organization
2023/12/18 - 2023/12/21 15th Conference on Dynamical Systems Applied to Biology and Natural Sciences - ICSDS2023 (2023/12/18 - 2024)
Conference (Member of the Organising Committee)
2022/10/15 - 2022/10/18 Workshop: O Futuro da Estatística na ULisboa (The future of Statistics at Lisbon University) (2022/10/15 - 2022/10/16)
Workshop (Co-organisor)
Universidade de Lisboa Centro de Estatística e Aplicações, Portugal

Universidade de Lisboa Centro de Matemática Computacional e Estocástica, Portugal

Event participation

Activity description
Type of event
Event name
Institution / Organization
2019/07/10 - 2019/07/10 Almoços com Ciências (Lunch time at Ciências) - Discussion on "Statistical Literacy" Almoços com Ciências
Universidade de Lisboa Faculdade de Ciências, Portugal

Jury of academic degree

Topic
Role
Candidate name (Type of degree)
Institution / Organization
2023/11/29 O Papel do PLS, PLS-DA E CLUSTOFVAR no Desenvolvimento de Modelos Preditivos de Asma, Eczema e Rinite na Coorte Geração XXI
(Thesis) Main arguer
Natacha dos Santos Oliveira (Master)
Universidade de Aveiro, Portugal
2023/07/21 Modelação da tarifação não-vida
(Thesis) Arguer
Tiago Alexandre Ribeiro Morais (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
2023/07/06 Multivariate analysis applied in the study of the nutritional quality of processed products
(Thesis) Arguer
Beatriz Pimentel Pereira (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
2021/07/02 Supervised classification methods applied to the diagnosis of Obstructive Sleep Apnea - a comparative study
President of the jury
Ana Margarida Rodrigues dos Santos Martins Pereira (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
2021/05/27 Spatial distribution of the severity of lung cancer at diagnosis – is it related to socioeconomic factors and access to primary health care?
President of the jury
Mariana Reis Vieira (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
2020/11/06 Risk factors for Amyotrophic Lateral Sclerosis (ALS): the effect of high-intensity sport
President of the jury
Ana Rita Oliveira Henriques (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
2019/11/11 Effects of Pharmaceuticals on the Reproduction of Aquatic Organisms: a Meta-Analysis
(Thesis) Main arguer
David Gil Valente Lopes (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
2013 A perceção do dador de sangue face à dádiva de sangue e ao estatuto do dador de sangue Rosa Margarete Pereira de Figueiredo Cardoso (Master)
Instituto Politécnico de Lisboa Escola Superior de Tecnologia da Saúde de Lisboa, Portugal

Committee member

Activity description
Role
Institution / Organization
2023/05/31 - Current Comissão de Apoio ao Impulso Jovem e Adulto (no âmbito do Plano de Recuperação e Resiliência) - Youth and Adult Boost Support Committee (as part of the Recovery and Resilience Plan)
Member
2023/01/01 - Current Vice-Director of the Centre of Statistics and its Applications (FCUL)
President / Vice-president
2022 - Current Comissão de Ética de Ciências (FCUL) - Ciências Ethics Council
Member
2021/06/01 - Current Vice-Director of the PhD in Statistics and Operations Research (FCUL)
President / Vice-president
2017/01/01 - Current Scientific Committee - Master in Biostatistics (FCUL)
Member
2024/01/01 - 2026/12/31 Vice-President of the Portuguese Statistical Society (SPE)
President / Vice-president
2017/01/01 - 2022/12/31 Director of the Centre of Statistics and Operations Research
Director
Universidade de Lisboa Centro de Estatística e Aplicações, Portugal
2019 - 2022 Ethics Council - Comissão de Ética para Recolha e Proteção de Dados de Ciências (FCUL)
Member
Universidade de Lisboa Faculdade de Ciências, Portugal
2018 - 2022 Scientific Council - Faculty of Sciences, Lisbon University
Member
2009/10/01 - 2016/12/31 Director of the Master in Biostatistics (FCUL)
Coordinator

Conference scientific committee

Conference name Conference host
2023/10/11 - 2023/10/14 XXVI Conference of the Portuguese Statical Society Universidade do Minho
2022/07/04 - 2022/07/07 Computational and Applied Statistics 2022 (CAS) workshop at 22th International Conference on Computational Science and Its Applications (ICCSA 2022) University of Malaga, Spain
2021/02/12 - 2021/02/13 Jornadas de Estatística Médica (Medical Statistics Conferences) Centre of Statistics and Applications, Faculty of Sciences - Lisbon University
2020/07/01 - 2020/07/04 Computational and Applied Statistics 2020 (CAS) workshop at 20th International Conference on Computational Science and Its Applications (ICCSA 2020) University of Cagliari, Italy

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2018/04/02 - 2018/04/05 ABSTAT2018 - Advanced Biostatistics for Bioinformatics Tool Users in R GTPB Bioinformatics training programme (Outros) Instituto Gulbenkian de Ciência, Portugal
2017/04/10 - 2017/04/13 ABSTAT2017 - Advanced Biostatistics for Bioinformatics Tool Users in R GTPB Bioinformatics training programme (Outros) Instituto Gulbenkian de Ciência, Portugal

Interview (newspaper / magazine)

Activity description Newspaper / Forum
2018/07 Estatística: investigar a ciência do Presente Perspetivas

Interview (tv / radio show)

Program Topic
2018/10/19 - 2018/10/19 "Edição da Manhã" - SIC Notícias TV Channel Centre of Statistics and its Applications celebrates the European Day of Statistics

Journal scientific committee

Journal title (ISSN) Publisher
2017 - Current REVSTAT - Statistical Journal (1645-6726) INE
2018 - 2019 Revstat - Special Issue on Biometry, 17 (2) INE
Distinctions

Award

2023 Best Poster Award - 45th ESPEN Congress on Clinical Nutrition & Metabolism
2022 Professor of the Semester (2.nd year - 1.st semester 2022/2023), Bioestatistics - Lic. Biology)
2020 Best Oral Communication - Jornadas de Estatística Médica (FCUL)
Universidade de Lisboa Centro de Estatística e Aplicações, Portugal
2020 Best Poster in the category "Translational Research" - at the "Fundação AstraZeneca Innovate Competition"
2020 Best Poster - Conference "Health Decision Making: Clinical Trials"
2020 Best Paper Award in the 20th International Conference on Computational Science and Applications (ICCSA 2020)
2019 Professor of the Semester (2.nd year - 1.st semester 2019/2020, Biostatistics - Lic. Biology)
2018 Best Poster - "Validation of the Nursing Diagnosis Risk for Falls in Elderly"
2018 Professor of the Semester (2.nd year - 1.st semester 2018/2019, Biostatistics - Lic. Biology)
2016 Inovação CNOIV
Instituto da Vinha e do Vinho IP, Portugal