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Sara Filipa Silva Pestana. Concluiu o(a) Mestrado em Mestrado em Genética Molecular e Biomedicina em 2016 pelo(a) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia e Licenciatura em Ciências Biomédicas em 2014 pelo(a) Universidade do Algarve Faculdade de Ciências e Tecnologia. É PhD student in ProRegeM – Mechanisms of Disease and Regenerative Medicine no(a) Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas. Publicou 2 artigos em revistas especializadas. No seu currículo Ciência Vitae os termos mais frequentes na contextualização da produção científica, tecnológica e artístico-cultural são: Left-right asymmetry; cilia; Chemosensation Model; Two-cilia Hypothesis; Pkd2; expression pattern studies; Domínio/Área Científica::Engenharia e Tecnologia::Outras Engenharias e Tecnologias; .
Identification

Personal identification

Full name
Sara Filipa Silva Pestana

Citation names

  • Pestana, Sara

Author identifiers

Ciência ID
651B-A763-ECF5
ORCID iD
0000-0002-0995-0040

Email addresses

  • sara.pestana@nms.unl.pt (Professional)

Telephones

Telephone
  • 218803101 (Professional)

Addresses

  • Centro de Estudos de Doenças Crónicas. Rua Câmara Pestana nº 6, 6-A Edifício CEDOC II, 1150-082 L, Lisboa, Lisboa, Portugal (Professional)

Knowledge fields

  • Natural sciences - Biological Sciences - Developmental Biology
  • Medical and Health Sciences - Health Sciences

Languages

Language Speaking Reading Writing Listening Peer-review
English Intermediate (B1) Intermediate (B1) Intermediate (B1) Intermediate (B1)
Education
Degree Classification
2018/03/01 - 2023/03/26
Concluded
Mecanismos de doenças e medicina regenerativa (Doutoramento)
Major in Testing the role of extracellular vesicles in the early left right patterning
Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas, Portugal
"Testing the role of extracellular vesicles in the early left right patterning" (THESIS/DISSERTATION)
2016
Concluded
Genética Molecular e Biomedicina (Mestrado integrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
"Screening for asymmetrically expressed genes in the left-right organizer of the zebrafish embryo" (THESIS/DISSERTATION)
17
2014
Concluded
Ciências Biomédicas (Licenciatura)
Universidade do Algarve Faculdade de Ciências e Tecnologia, Portugal
"Identificação dos locais de expressão e acumulação da GRP em peixe-zebra" (THESIS/DISSERTATION)
16
Affiliation

Others

Category
Host institution
Employer
2017/02/01 - 2018/02/28 Gestão de Laboratório no grupo 'Cilia regulation and Disease' Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas, Portugal
Projects

Grant

Designation Funders
2022/05/01 - 2022/08/31 Testing the role of Extracellular Vesicles in early Left-Right Patterning
COVID/BD/152586/2022
Universidade Nova de Lisboa Medical School, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2018/03/01 - 2022/04/30 Testing the role of Extracellular Vesicles in early Left-Right Patterning
SFRH/BD/130272/2017
Universidade Nova de Lisboa Medical School, Portugal
Fundação para a Ciência e a Tecnologia
Concluded

Contract

Designation Funders
2019/01/01 - 2019/12/31 iNOVA4Health - Programa de Medicina Translacional (iBET, CEDOC/FCM, IPOLFG e ITQB)
UID/Multi/04462/2019
Instituto de Biologia Experimental e Tecnológica, Portugal

Universidade Nova de Lisboa Medical School, Portugal

Universidade Nova de Lisboa, Portugal

Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica António Xavier, Portugal

Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas, Portugal

Instituto Português de Oncologia de Lisboa Francisco Gentil EPE, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2017/01/01 - 2018/02/28 Quantitative analysis of asymmetric gene expression in the left-right organizer in response to flow forces: what comes downstream of cilia driven flow?
Research Fellow
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal

Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Journal article
  1. Sampaio, Pedro; Pestana, Sara; Bota, Catarina; Guerrero, Adán; Telley, Ivo A; Smith, David; Lopes, Susana Santos. "Fluid extraction from the left-right organizer uncovers mechanical properties needed for symmetry breaking". eLife 12 (2023): http://dx.doi.org/10.7554/elife.83861.
    10.7554/elife.83861
  2. Oliveira, Inês; Jacinto, Raquel; Pestana, Sara; Nolasco, Fernando; Calado, Joaquim; Lopes, Susana Santos; Roxo-Rosa, Mónica. "Zebrafish Model as a Screen to Prevent Cyst Inflation in Autosomal Dominant Polycystic Kidney Disease". International Journal of Molecular Sciences 22 16 (2021): 9013. http://dx.doi.org/10.3390/ijms22169013.
    10.3390/ijms22169013
  3. Pinto, Andreia L.; Rasteiro, Margarida; Bota, Catarina; Pestana, Sara; Sampaio, Pedro; Hogg, Claire; Burgoyne, Thomas; Lopes, Susana S.. "Zebrafish Motile Cilia as a Model for Primary Ciliary Dyskinesia". International Journal of Molecular Sciences 22 16 (2021): 8361. http://dx.doi.org/10.3390/ijms22168361.
    Open access • Published • 10.3390/ijms22168361 • Assistant staff
  4. Jacinto, Raquel; Sampaio, Pedro; Roxo-Rosa, Mónica; Pestana, Sara; Lopes, Susana S.. "Pkd2 Affects Cilia Length and Impacts LR Flow Dynamics and Dand5". Frontiers in Cell and Developmental Biology 9 (2021): http://dx.doi.org/10.3389/fcell.2021.624531.
    Published • 10.3389/fcell.2021.624531
  5. Kuhns, Stefanie; Seixas, Cecília; Pestana, Sara; Tavares, Bárbara; Nogueira, Renata; Jacinto, Raquel; José S Ramalho; et al. "Rab35 controls cilium length, function and membrane composition". EMBO reports (2019): http://dx.doi.org/10.15252/embr.201847625.
    10.15252/embr.201847625
  6. Tavares, Barbara; Jacinto, Raquel; Sampaio, Pedro; Pestana, Sara; Pinto, Andreia; Vaz, Andreia; Roxo-Rosa, Mónica; et al. "Notch/Her12 signalling modulates, motile/immotile cilia ratio downstream of Foxj1a in zebrafish left-right organizer". eLife 6 (2017): http://dx.doi.org/10.7554/elife.25165.
    10.7554/elife.25165
Preprint
  1. Pedro Sampaio; Sara Pestana; Adán Guerrero; Ivo A. Telley; David. J. Smith; Susana S. Lopes. "Fluid extraction from the left-right organizer uncovers mechanical properties needed for symmetry breaking". 2022. https://doi.org/10.1101/2022.04.21.489023.
    10.1101/2022.04.21.489023
Thesis / Dissertation
  1. Pestana, Sara Filipa Silva. "Screening for asymmetrically expressed genes in the left-right organizer of the zebrafish embryo". Master, 2016. http://hdl.handle.net/10362/50527.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2021/09/14 The extracellular vesicles in left-right organizer of zebrafish 1st Meeting of the Portuguese network on Extracellular Vesicles
i3S
2019 The extracellular vesicles in left-right organizer International Conference on Cilia, Flagella and Centrosomes
French Society of Cilia (Paris, France)
2016 Screening for asymmetrically expressed genes in the left-right organizer of the zebrafish embryo Jornadas Intercalares das Dissertações Anuais dos Mestrados
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia (Caparica, Portugal)

Event participation

Activity description
Type of event
Event name
Institution / Organization
2021/12/01 - 2021/12/10 Apresentação poster "The extracellular vesicles in left-right organizer of zebrafish"
Conference
Cell biology virtual 2021
American Society for Cell Biology, United States
2020/04/14 - 2020/06/30 Voluntariado na realização dos testes de diagnóstico ao COVID-19. COVID-19 Task Force - CEDOC
Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas, Portugal
2019/08/04 - 2019/08/09 Apresentação poster do trabalho "The extracellular vesicles in left-right organizer"
Conference
FASEB: The Biology of Cilia and Flagella
Federation of American Societies for Experimental Biology, United States
2018/11/07 - 2018/11/10 Apresentação poster do trabalho "Testing the role of extracellular vesicles in early left-right patterning"
Conference
Joint meeting of the Portuguese, Spanish and French societies for development biology / 4th Meeting of the Portuguese society for development biology
2018/10/02 - 2018/10/05 Apresentação poster do trabalho "Testing the role of extracellular vesicles in early left-right patterning"
Conference
EMBO Workshop Cilia 2018
2018/02/16 - 2018/02/17 Apresentação poster do trabalho "Testing the role of extracellular vesicles in early left-right patterning"
Conference
1st Meeting on Vesicular Biology
2018/02/06 - 2018/02/09 Apresentação poster do trabalho "A new possible role of V-ATPase in the left-right development"
Conference
3rd BEAT-PCD Conference and Training School / 4th PCD Training School
2017/06/01 - 2017/06/02 Apresentação poster do trabalho "The Role of Rabconnectin3a in Cilia Length Regulation"
Conference
SINAL 2017, 8th Meeting on Signal Transduction
2017/04/18 - 2017/04/21 Apresentação poster do trabalho "The Role of Rabconnectin3a in Cilia Length Regulation"
Conference
2nd BEAT-PCD Conference and Training School / 3rd PCD Training School
2017/02/12 - 2017/02/17 Apresentação poster do trabalho "Notch signalling decides on cilia motility in the left-right organizer"
Conference
Gordon Research Conference on Cilia, mucus and mucuciliary interactions

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2019/03/29 - 2019/04/01 Research skills development course (RSD) Research skills development course (RSD) (Outros) Universidade Nova de Lisboa, Portugal
Distinctions

Award

2019 Melhor apresentação oral na "International Conference on Cilia, Flagella and Centrosomes"