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My name is Duangnapa Kiriwan, and I have been working as a research assistant for four years under the supervision of Assoc.Prof.Dr. Kiattawee Choowongkomon. I finished a Bachelor's degree in biochemistry from Burapha University in Thailand and then a Master's degree in genetic engineering and bioinformatics from Kasetsart University in 2021. I've authored 15 papers in peer-reviewed journals that have been cited in ISI Web of Science/Scopus (2 as first author, 13 as co-author). My research interests include computer-assisted drug design Molecular modelling, Molecular docking and Molecular dynamics simulation and AI-algorithm involved inhibitors design.
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Identification

Personal identification

Full name
Duangnapa Kiriwan

Citation names

  • kiriwan, duangnapa

Author identifiers

Ciência ID
6812-40DD-2209
ORCID iD
0000-0003-4824-7398
Scopus Author Id
57210797600

Email addresses

  • up202310671@up.pt (Professional)

Websites

Knowledge fields

  • Natural sciences - Biological Sciences - Biochemistry

Languages

Language Speaking Reading Writing Listening Peer-review
Thai (Mother tongue)
English Intermediate (B1) Intermediate (B1) Intermediate (B1) Intermediate (B1) Intermediate (B1)
Education
Degree Classification
2024/02 - 2028
Ongoing
 Química Sustentável (Doutoramento)
Universidade do Porto Faculdade de Ciências, Portugal
2017/07 - 2021/06/16
Concluded
 Genetic Engineering and Bioinformatics (Master)
Department of Biochemistry, Kasetsart university, Bangkok, Thailand, Thailand
"In Silico Structural Elucidation of The Rabies RNA-Dependent RNA Polymerase (RdRp) And Human Epidermal Growth Factor Receptor Tyrosine Kinase Towards the Identification of Potential Inhibitors " (THESIS/DISSERTATION)
 3.83/4.00, 19/20
2011/01/29 - 2015/04/07
Concluded
 Biochemistry (Bachelor)
Department of Biochemistry, Burapha university, Bangkok, Thailand, Thailand
"Homologous protein interaction network and functional analysis of salicylic acid biosynthesis pathway" (THESIS/DISSERTATION)
 2.92/4.00, 16/20
Affiliation

Science

Category
Host institution 		Employer
2016/01/07 - Current Research Assistant (Research) Kasetsart University Department of Biochemistry, Thailand
Department of Biochemistry, Kasetsart university, Bangkok, Thailand, Thailand
2022/01/17 - 2022/08/26 Research Trainee (Research) REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
Kasetsart University, Thailand
2020/03/01 - 2020/06/23 Research Trainee (Research) Universidade do Porto Departamento de Química e Bioquímica, Portugal
Kasetsart University, Thailand
2019/07/01 - 2019/07/19 Research Trainee (Research) Institute of Quantum Beam Science of Ibaraki University , Japan
Kasetsart University, Thailand
2018/06/01 - 2018/08/31 Research Trainee (Research) Pharmaceutical Science, University of Vienna, Austria, Austria
Kasetsart University, Thailand
2015/04/14 - 2015/09/30 Research Assistant (Research) Department of Biochemistry, Burapha university, Bangkok, Thailand, Thailand
Department of Biochemistry, Burapha university, Bangkok, Thailand, Thailand
Outputs

Publications

Conference poster
  1. kiriwan, duangnapa; Choowongkomon, K.. Corresponding author: Choowongkomon, K.. "In Silico Structural Elucidation of The Rabies RNA-Dependent RNA Polymerase (RdRp)". Paper presented in World Rabies Day 2020, Thailand, 2020.
  2. kiriwan, duangnapa; Choowongkomon, K.. Corresponding author: Choowongkomon, K.. "Virtual Screening with Rabies virus RNA Dependent RNA Polymerase (RdRp) to Design Viral Therapeutics". Paper presented in 14th International Symposium of the Protein Society of Thailand (PST2019), 2019.
Journal article
  1. Tran, Thi-Minh-Dinh; Aonbangkhen, Chanat; Duong, Thuc-Huy; Nguyen, Thu-Hoang-Mai; Ho, Minh-Truong-Tho; Chavasiri, Warinthorn; Wongsuwan, Sutthida; et al. "Diphenyl ethers from the cultured lichen mycobiont of Graphis handelii Zahlbr". Heliyon 10 4 (2024): e25763. http://dx.doi.org/10.1016/j.heliyon.2024.e25763.
    10.1016/j.heliyon.2024.e25763
  2. Suwattanasophon, Chonticha; Mistlberger-Reiner, Agnes; Alberdi-Cedeño, Jon; Pignitter, Marc; Somoza, Veronika; König, Jürgen; Lamtha, Thomanai; et al. "Identification of the Brucea javanica Constituent Brusatol as a EGFR-Tyrosine Kinase Inhibitor in a Cell-Free Assay". ACS Omega 8 31 (2023): 28543-28552. http://dx.doi.org/10.1021/acsomega.3c02931.
    10.1021/acsomega.3c02931
  3. Thitinan Aiebchun; Natchaya Rasri; Duangnapa Kiriwan; Suradej Siripattanapipong; kiattawee choowongkomon. "In Vitro and In Silico Studies of Kinase Inhibitor of MAPK3 Protein to Determine Leishmania martiniquensis Treatment". Acta Parasitologica (2023): http://dx.doi.org/10.1007/s11686-023-00659-0.
    10.1007/s11686-023-00659-0
  4. Rattanabunyong, Siriluk; Choengpanya, Khuanjarat; Suwattanasophon, Chonticha; Kiriwan, Duangnapa; Wolschann, Peter; Lamtha, Thomanai; Shaikh, Abdul Rajjak; Rattanasrisomporn, Jatuporn; Choowongkomon, Kiattawee. "Biochemical and structural comparisons of non-nucleoside reverse transcriptase inhibitors against feline and human immunodeficiency viruses". Journal of Veterinary Science 24 5 (2023): http://dx.doi.org/10.4142/jvs.22326.
    10.4142/jvs.22326
  5. Buabarn Kuaprasert; Penchit Chitnumsub; Ubolsree Leartsakulpanich; pinpunya riangrungroj; Wipa Suginta; Saovanee Leelayoova; Mathirut Mungthin; et al. "Dual role of azo compounds in inhibiting Plasmodium falciparum adenosine deaminase and hemozoin biocrystallization". Experimental Parasitology 243 (2022): 108384-108384. http://dx.doi.org/10.1016/j.exppara.2022.108384.
    10.1016/j.exppara.2022.108384
  6. Lueacha Tabtimmai; Prapasri Supakun; Borvornvat Toviwek; Nattanan Jiwacharoenchai; Duangnapa Kiriwan; Thitinan Aiebchun; Matthew Paul Gleeson; kiattawee choowongkomon. "4-Aryl-N-phenylpyrimidin-2-amines targeting EGFR-tyrosine kinase attenuated EGFR-expressing cell lines". European Journal of Medicinal Chemistry Reports 5 (2022): 100062-100062. http://dx.doi.org/10.1016/j.ejmcr.2022.100062.
    10.1016/j.ejmcr.2022.100062
  7. "Identification of tripeptides against tyrosine kinase domain of EGFR for lung cancer cell inhibition by in silico and in vitro studies". Chemical Biology & Drug Design 99 3 (2022): 456-469. http://dx.doi.org/10.1111/cbdd.14010.
    10.1111/cbdd.14010
  8. "A novel cyclic NP1 reveals obstruction of EGFR kinase activity and attenuation of EGFR-driven cell lines". Journal of Cellular Biochemistry 123 2 (2022): 248-258. http://dx.doi.org/10.1002/jcb.30160.
    10.1002/jcb.30160
  9. "Generation of a nanobody against HER2 tyrosine kinase using phage display library screening for HER2-positive breast cancer therapy development". Protein Engineering, Design and Selection 34 (2021): http://dx.doi.org/10.1093/protein/gzab030.
    10.1093/protein/gzab030
  10. Wongsamart, R.; Kiriwan, D.; Suwattanasophon, C.; Yokthongwattana, K.; Choowongkomon, K.. "Computational analysis of homo-dimerization of chloroplast-localized chaperonin from the alga Chlamydomonas reinhardtii". Agriculture and Natural Resources 55 5 (2021): http://dx.doi.org/10.34044/j.anres.2021.55.5.03.
    10.34044/j.anres.2021.55.5.03
  11. "Molecular dynamics, MM/PBSA and in vitro validation of a novel quinazoline-based EGFR tyrosine kinase inhibitor identified using structure-based in silico screening". Journal of Molecular Graphics and Modelling 99 (2020): 107639-107639. http://dx.doi.org/10.1016/j.jmgm.2020.107639.
    10.1016/j.jmgm.2020.107639
  12. "Chamuangone from Garcinia cowa leaves inhibits cell proliferation and migration and induces cell apoptosis in human cervical cancer in vitro". Journal of Pharmacy and Pharmacology 72 3 (2020): 470-480. http://dx.doi.org/10.1111/jphp.13216.
    10.1111/jphp.13216
  13. "Cell-penetrable nanobodies (transbodies) that inhibit the tyrosine kinase activity of EGFR leading to the impediment of human lung adenocarcinoma cell motility and survival". Journal of Cellular Biochemistry 120 10 (2019): 18077-18087. http://dx.doi.org/10.1002/jcb.29111.
    10.1002/jcb.29111
  14. "In Vitro Antimalarial Activity and Cytotoxity of 20 Ethanolic Crude Extracts from Thai Herbs Against Plasmodium Falciparum TM267". Songklanagarind Medical Journal 35 2 (2017): 109-109. http://dx.doi.org/10.31584/smj.2017.35.2.693.
    10.31584/smj.2017.35.2.693
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2024/05/10 DEVELOPMENT AND APPLICATION OF A MULTI-LEVEL COMPUTATIONAL AND IN VITRO APPROACH FOR IDENTIFYING MAPK3 INHIBITORS IN LEISHMANIA MARTINIQUENSIS AND LEISHMANIA ORIENTALIS BIOPHYSICS FESTIVAL – 4 th Meeting of Young Biophysicists
Faculty of Sciences of University of Beira Interior, Covilhã, Portugal (Covilhã, Portugal)
2019/07/13 In Silico Structural Elucidation of The Rabies RNA-Dependent RNA Polymerase (RdRp)" Asian workshop of Experiment and Theory in Quantum Beam Molecular Science 2019
(Mito, Japan)

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2019/04/18 - 2019/04/19 Protein Bioinformatics workshop (2019/04/18 - 2019/04/19)
Workshop (Other)
 Kasetsart University Department of Biochemistry, Thailand