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Maria Margarida Diogo finished her PhD thesis in Biotechnology at IST in 2004. She is presently an Associate Professor with Tenure at the Department of Bioengineering of IST, lecturing, among others, the courses Cell and Tissue Engineering and Stem Cell Bioengineering to all MSc courses coordinated by DBE. She was awarded with the distinction of Excellent Teacher by the Pedagogical Council of Técnico since the first curricular year after being hired, in 2014. She has had an intense post-graduate teaching and management activities in several PhD programs, in particular the PhD program in Bioengineering: Cell Therapies and Regenerative Medicine. She is regularly invited to lecture in post-graduate national and international advanced courses such as the 2nd International Course on Regenerative Medicine Manufacturing, co-organized by Georgia Tech, IST and Loughborough University, in 2016. She is senior researcher at SCERG-iBB, leading the Focus Area Biology and Engineering of Pluripotent Stem Cells, which she pioneered since 2010s. In January 2021 she established her own lab entitled "Stem Cell Advanced Tissue Models Lab", at SCERG-iBB, focusing the development of advanced neural and cardiac tissue models and their in vitro applications. She supervised/co-supervised 5 post-docs, 12 PhD students and 28 MSc students. She was selected for oral presentations in highly recognized international conferences, such as the Stem Cell Engineering conference and the Scale-up and Manufacturing of Cell-based Therapies. Since 2010 she leaded several national projects as PI (e.g. 3 FCT projects) and she is a WP leader and coordinator at IST of a recently granted collaborative EU project. Her international recognition is also demonstrated by several international publications and an extensive group of national and international instrumental collaborations with experts in stem cell biology and bioengineering that yielded several highly-cited co-authored publications and the co-supervision of several PhD students and post-docs. She published a total of 58 peer-reviewed papers and she has an h-index of 29 and more than 2500 citations, with an average 32 citations per article. As one of her main achievements, she recently published an original research paper in Nature Communications as corresponding author. She published 15 book chapters and 1 book and she is the co-editor of 2 books. In the last two years she co-authored 2 patent applications. She was the member of the panel of evaluation of FCT PhD scholarships in 2018 and 2020. She has had intense management activities as responsible for the communication and outreach activities of the Department of Bioengineering of IST and she is member of the scientific commissions of the MSc courses in Biomedical Engineering, Biological Engineering and Biotechnology at IST. She is a member of Assembleia de Escola of IST. She is presently a member of Rede Saúde of Universidade de Lisboa (working group Neurodegenerative diseases) that she previously co-chaired. She is regularly invited to be a member of the jury in several MSc and PhD thesis in several academic institutions. She is a member of the board o directors of the Collaborative Laboratory AccelBio. She is the secretariate of the the board of directors of the Portuguese Society for Stem Cells and Cell Therapies.
Identification

Personal identification

Full name
Maria Margarida Diogo

Citation names

  • Diogo, Maria Margarida

Author identifiers

Ciência ID
691F-3B15-C155
ORCID iD
0000-0002-6270-4455
Researcher Id
ABF-4341-2020
Scopus Author Id
6701492791

Email addresses

  • margarida.diogo@tecnico.ulisboa.pt (Professional)

Telephones

Mobile phone
  • 962592617 (Personal)

Addresses

  • Av. Rovisco Pais, 1040-001 Lisboa, Portugal, 1049-001, Lisboa, Lisboa, Portugal (Professional)

Websites

Knowledge fields

  • Engineering and Technology - Medical Engineering - Medical Laboratory Technology

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
Spanish; Castilian Intermediate (B1) Beginner (A1) Intermediate (B1) Intermediate (B1)
Education
Degree Classification
2004/05/01 - 2008/03/01
Concluded
Bioengenharia de Células Estaminais (Pós-doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2000/01/01 - 2004/04/01
Concluded
Biotecnologia (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
Aprovado
1997/09/01 - 1999/11/01
Concluded
Biotecnologia (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
Affiliation

Science

Category
Host institution
Employer
2014/01 - Current Researcher (Research) Universidade de Lisboa Instituto Superior Técnico, Portugal
Universidade de Lisboa Instituto de Bioengenharia e Biociências, Portugal
2008 - 2013/12/31 Auxiliary Researcher (Research) Instituto de Biotecnologia e Bioengenharia, Portugal
Universidade de Lisboa Instituto Superior Técnico, Portugal

Teaching in Higher Education

Category
Host institution
Employer
2023/09/01 - Current Associate Professor (University Teacher) Universidade de Lisboa Instituto Superior Técnico, Portugal
2014/01/01 - 2023/08/31 Assistant Professor (University Teacher) Universidade de Lisboa Instituto Superior Técnico, Portugal
Universidade de Lisboa Instituto Superior Técnico, Portugal
Projects

Contract

Designation Funders
2023/02 - Current Engineering an innervated heart organoid - the initial step for in vitro modulation of neuro-cardiac cross-talk
2022.02251.PTDC
Researcher
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal
Ongoing
2023/01/01 - Current CD24: an important molecule for the regeneration of the cardiac tissue?
2022.09110.PTDC
Researcher
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Ongoing
2022/09/01 - Current Engineering a retinal-thalamus-cortical tri-way brain assembloid for modeling visual pathway circuit developmental defects in Rett Syndrome (RTT)
Principal investigator
Associação para o Desenvolvimento do Instituto Superior Técnico, Portugal
Universidade de Lisboa Instituto de Bioengenharia e Biociências
Ongoing
2015 - Current Scaling up cardiomyocyte production from human induced pluripotent stem cells (hiPSC) through intrinsic control of cell differentiation on bioreactors
iBB
Principal investigator
Universidade de Lisboa Instituto de Bioengenharia e Biociências, Portugal
Universidade de Lisboa Instituto de Bioengenharia e Biociências
Concluded
2009/01/01 - Current BioScale Colab: Collaborative Laboratory to foster translation and drug discovery
BioScale
Researcher
Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal

Associação para o Desenvolvimento do Instituto Superior Técnico, Portugal

Universidade de Coimbra, Portugal

Biocant Associação de Transferência de Tecnologia, Portugal
2023/06/01 - 2027/05/31 EURAS - EUropean network for neurodevelopmental RASopathies, Collaborative Project funded by HORIZON-HLTH-2022-DISEASE-06-04: Development of new effective therapies for rare diseases.
HORIZON-HLTH-2022-DISEASE-06-04
Principal investigator
Ongoing
2022/01/01 - 2024/12/31 Analyzing Neuroimmune dysregulation in Alzheimer´s disease toward a Therapy with miRNA-loaded Exosomes
PTDC/MED-NEU/2382/2021
Researcher
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
Fundação para a Ciência e a Tecnologia - Portugal
Ongoing
2022/01/01 - 2024/12/31 TAT-TrkB, a novel neuroprotective compound to fight Alzheimer´s disease
MB-35-2021
Researcher
Santa Casa da Misericórdia de Lisboa
Ongoing
2021/11/01 - 2024/10/31 RNA mis-splicing in hypertrophic cardiomyopathy: opportunities for diagnosis and therapy
HR20-00322
Researcher
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal
Obra Social La Caixa
Ongoing
2021/02/01 - 2024/01/31 New Technologies for stem cell manufacturing bioprocess monitoring and artificial intelligence-based modelling
PTDC/EQU-EQU/3853/2020
Researcher
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2018/10/01 - 2022/09/30 Mini-Hearts - Organoid Engineering for Production of 3D Cardiovascular Microtissues from Human Induced Pluripotent Stem Cells for Cardiotoxicity Assays
PTDC/EMD-TLM/29728/2017
Principal investigator
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2018/10/01 - 2021/09/30 CardioWheel - Upscaling the Production of Human Pluripotent Stem Cell-derived Cardiomyocytes using Vertical-Wheel Bioreactors
PTDC/EQU-EQU/29653/2017
Researcher
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal
Fundação para a Ciência e a Tecnologia - Portugal
Ongoing
2018/06/01 - 2021/05/31 Cerebex - Generation of gene-edited cerebellar organoids for ataxia research
PTDC/BTM-SAL/29298/2017
Researcher
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal
Fundação para a Ciência e a Tecnologia - Portugal
Ongoing
2020/01/01 - 2020/12/31 Osteoglutis: Diferenciação osteogénica como alvo terapêutico no tratamento do mieloma múltiplo
Researcher
Universidade de Lisboa Instituto de Bioengenharia e Biociências, Portugal
Ongoing
2016/12 - 2019/11 Precise: Accelerating progress towards the new era of Precision Medicine
SAICTPAC/0021/2015
Researcher
Fundação Ciência e Tecnologia - FCT
Ongoing
2014/09 - 2017/09 CARDIOSTEM - Engineered cardiac tissues and stem cell-based therapies
MITP-TB/ECE/0013/2013
Researcher
Fundação para a Ciência e a Tecnologia - Portugal (MIT Portugal Program)
Concluded
2014/01 - 2014/12 BioNeuralNet: Bioengineering the Neural Commitment of Human Pluripotent Stem Cells: Rational Approaches for the Clinical-Grade Production of Neuronal Cells
EXPL/BBB-EBI/0294/2013
Researcher
Universidade de Lisboa Instituto Superior Técnico, Portugal
Fundação para a Ciência e a Tecnologia - Portugal
Concluded
2012/01 - 2014/12 StemPure - Bioprocess for Production and Purification of Human Pluripotent Stem Cell-Derived Neural Cells for Regenerative Medicine Applications
PTDC/EBB-BIO/122504/2010
Principal investigator
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal
Fundação para a Ciência e a Tecnologia - Portugal
Concluded
2010/04 - 2013/09 StemCellQCM - Acoustic detectors for stem cell adhesion and differentiation
PTDC/SAU-BEB/105189/2008
Principal investigator
Fundação para a Ciência e a Tecnologia - Portugal
Concluded
2010/01 - 2012/12 Stem Array - Exploring human embryonic stem cell fate using 3-D cellular microarrays
PTDC/EBB-BIO/101088/2008
Principal investigator
Universidade de Lisboa Instituto Superior Técnico, Portugal
Fundação para a Ciência e a Tecnologia - Portugal
Concluded
2010/01 - 2012/12 Integrated Process for the Expansion and Neural Differentiation of Human Embryonic Stem Cells in Stirred Suspension Bioreactors
PTDC/EQU-ERQ/105277/2008
Fundação para a Ciência e a Tecnologia - Portugal
2010/07 - 2012/11 Large-Scale Expansion of Human Pluripotent Stem Cell-Derived Neural Stem Cells in Bioreactors
HEALTH-2007-1.4-6
Researcher
European Commission
Concluded
Outputs

Publications

Book
  1. Cabral, J.M.S.; De Silva, C.L.; Chase, L.G.; Diogo, M.M.. Introduction. 2016.
  2. Fernandes, T.G.; Diogo, M.M.; Cabral, J.M.S.. Stem Cell Bioprocessing: For Cellular Therapy, Diagnostics and Drug Development. 2013.
Book chapter
  1. Miranda, Cláudia C.; Fernandes, Tiago G.; Diogo, M. Margarida; Cabral, Joaquim M. S.. "Human Pluripotent Stem Cells: Applications and Challenges for Regenerative Medicine and Disease Modeling". In Advances in Biochemical Engineering/Biotechnology. Springer Berlin Heidelberg, 2020.
    10.1007/10_2019_117
  2. Branco, Mariana A.; Dias, Tiago P.; Cotovio, João P.; Rodrigues, Carlos A. V.; Fernandes, Tiago G.; Cabral, Joaquim M. S.; Diogo, Maria Margarida. "3D Microwell Platform for Cardiomyocyte Differentiation of Human Pluripotent Stem Cells". In Methods in Molecular Biology. Springer US, 2020.
    10.1007/7651_2020_336
  3. Diogo, Maria. "Three-Dimensional Cell-Based Microarrays: Printing Pluripotent Stem Cells into 3D Microenvironments". 2018.
    10.1007/978-1-4939-7792-5_6
  4. Rodrigues CAV, Branco M, Nogueira DES, Silva TP, Gomes AR, Diogo MM, Cabral JMS. "Bioreactors for Human Pluripotent Stem Cell Expansion and Differentiation". In Bioreactors for Stem Cell Expansion and Differentiation, 25-45. CRC Press, 2018.
    10.1201/9780429453144-2
  5. Badenes, S.M.; Fernandes-Platzgummer, A.; Rodrigues, C.A.V.; Diogo, M.M.; Da Silva, C.L.; Cabral, J.M.S.. "Microcarrier Culture Systems for Stem Cell Manufacturing". 2016.
    10.1016/B978-0-444-63265-4.00004-2
  6. Rodrigues, G.M.C.; Fernandes, T.G.; Rodrigues, C.A.V.; Diogo, M.M.; Cabral, J.M.S.. "Enrichment and Separation Technologies for Stem Cell-Based Therapies". 2016.
    10.1016/B978-0-444-63265-4.00009-1
  7. Rodrigues, G.M.C.; Fernandes, T.G.; Rodrigues, C.A.V.; Cabral, J.M.S.; Diogo, M.M.. "Purification of human induced pluripotent stem cell-derived neural precursors using magnetic activated cell sorting". 2015.
    10.1007/7651_2014_115
  8. Badenes, S.M.; Fernandes, T.G.; Rodrigues, C.A.V.; Diogo, M.M.; Cabral, J.M.S.. "Scalable expansion of human-induced pluripotent stem cells in xeno-free microcarriers". 2015.
    10.1007/7651_2014_106
  9. Rodrigues CAV, Fernandes TG, Diogo MM, da Silva CL, Cabral JMS. "Bioreactors for Stem Cell Expansion and Differentiation". In Handbook of Biomedical Engineering. Elsevier, 2014.
  10. Diogo, Maria Margarida; da Silva, Cláudia Lobato; Cabral, Joaquim M. S.. "Separation Technologies for Stem Cell Bioprocessing". In Stem Cells and Cell Therapy, 157-181. Springer Netherlands, 2013.
    10.1007/978-94-007-7196-3_7
  11. Rodrigues CAV, Fernandes TG, Diogo MM, da Silva CL, Cabral JMS. "Bioreactors for Stem Cell Expansion and Differentiation". In Stem Cell Engineering. CRC Press, 2012.
  12. Fernandes-Platzgummer, Ana; Diogo, Maria Margarida; da Silva, Claudia Lobato; Cabral, Joaquim M. S.. "Large-Scale Expansion of Mouse Embryonic Stem Cells on Microcarriers". edited by ZurNieden, N. I., 121-134. 2011.
    10.1007/978-1-60761-962-8_8
  13. Diogo, Maria Margarida; Queiroz, João Ant'onio; Prazeres, Duarte Miguel F.. "Purification of Plasmid DNA Vectors Produced in Escherichia coli for Gene Therapy and DNA Vaccination Applications". In Microbial Processes and Products, 165-178. Humana Press, 2005.
    10.1385/1-59259-847-1:165
  14. Prazeres, D.M.F.; Monteiro, G.A.; Ferreira, G.N.M.; Diogo, M.M.; Ribeiro, S.C.; Cabral, J.M.S.. "Purification of plasmids for gene therapy and DNA vaccination". 2001.
    10.1016/S1387-2656(01)07031-4
Conference paper
  1. Miranda, C.C.; Pascoal, J.F.; Fernandes, T.G.; Diogo, M.M.; Cabral, J.M.S.. "Expansion and neural commitment of human pluripotent stem cells as 3D suspension aggregates". 2014.
  2. Carmelo, J.G.; Fernandes-Platzgummer, A.; Weber, J.L.; Bear, M.-M.; Hervy, M.; Diogo, M.M.; Da Silva, C.L.; Cabral, J.M.S.. "Scalable production of human mesenchymal stem/stromal cells in microcarrier-based culture systems". 2014.
  3. Diogo, Maria Margarida. "Production of recombinant Human Leukemia Inhibitory Factor (LIF) in a Mammalian Cell Bioreactor: A first approach". Paper presented in 21st Annual Meeting of the European Society for Animal Cell Technology (ESACT), 2012.
  4. Rodrigues, C.A.V.; Diogo, M.M.; Da Silva, C.L.; Cabral, J.M.S.. "Design and operation of bioreactor systems for the expansion of pluripotent stem cell-derived neural stem cells". 2011.
    10.1109/ENBENG.2011.6026041
  5. Fernandes, T.G.; Diogo, M.M.; Dordick, J.S.; Cabral, J.M.S.. "Exploring embryonic stem cell fate using cellular microarrays". 2011.
    10.1109/ENBENG.2011.6026038
  6. Sousa, A.F.; Loureiro, J.; Diogo, M.M.; Cabral, J.M.S.; Freitas, P.P.. "Magnetic separation of undifferentiated mouse Embryonic Stem (ES) cells from neural progenitor cultures using a microfluidic device". 2011.
    10.1109/ENBENG.2011.6026049
  7. Fernandes, T.G.; Diogo, M.M.; Fernandes-Platzgummer, A.; Da Silva, C.L.; Cabral, J.M.S.. "Effect of hypoxia on proliferation and neural commitment of embryonic stem cells at different stages of pluripotency". 2011.
    10.1109/ENBENG.2011.6026039
Edited book
  1. Diogo, Maria Margarida. Engineering Strategies for Regenerative Medicine. Elsevier. 2019.
    Published • 10.1016/c2018-0-00059-6
  2. Cabral, J.M.S.; De Silva, C.L.; Chase, L.G.; Diogo, M.M.. Stem Cell Manufacturing. 2016.
Journal article
  1. P. Agostinho, Sofia; A. Branco, Mariana; E. S. Nogueira, Diogo; Diogo, Maria Margarida; S. Cabral, Joaquim M.; N. Fred, Ana L.; V. Rodrigues, Carlos A.. "Unsupervised analysis of whole transcriptome data from human pluripotent stem cells cardiac differentiation". Scientific Reports 14 1 (2024): http://dx.doi.org/10.1038/s41598-024-52970-z.
    10.1038/s41598-024-52970-z
  2. Mariana A. Branco; Tiago C. Nunes; Joaquim M. S. Cabral; Maria Margarida Diogo. "Developmental Toxicity Studies: The Path towards Humanized 3D Stem Cell-Based Models". International Journal of Molecular Sciences (2023): https://doi.org/10.3390/ijms24054857.
    10.3390/ijms24054857
  3. Miguel F. Tenreiro; Mariana A. Branco; João P. Cotovio; Joaquim M.S. Cabral; Tiago G. Fernandes; Maria Margarida Diogo. "Advancing organoid design through co-emergence, assembly, and bioengineering". Trends in Biotechnology (2023): https://doi.org/10.1016/j.tibtech.2022.12.021.
    10.1016/j.tibtech.2022.12.021
  4. Tiago P. Dias; Sandra N. Pinto; Sandra Carvalho; Tiago G. Fernandes; Fábio Fernandes; Maria Margarida Diogo; Maria C. Peleteiro; Manuel Prieto; Joaquim M. S. Cabral. "Cost-Effective Mechanical Aggregation of Cardiac Progenitors and Encapsulation in Matrigel Support Self-Organization in a Dynamic Culture Environment". International Journal of Molecular Sciences (2022): https://doi.org/10.3390/ijms232415785.
    10.3390/ijms232415785
  5. Tiago P. Dias; Tânia Baltazar; Sandra N. Pinto; Tiago G. Fernandes; Fábio Fernandes; Maria Margarida Diogo; Manuel Prieto; Joaquim M. S. Cabral; Ren-Ke Li. "Xeno-Free Integrated Platform for Robust Production of Cardiomyocyte Sheets from hiPSCs". Stem Cells International (2022): https://doi.org/10.1155/2022/4542719.
    10.1155/2022/4542719
  6. Mariana A. Branco; Tiago P. Dias; Joaquim M. S. Cabral; Perpetua Pinto-do-Ó; Maria Margarida Diogo. "Human multilineage pro-epicardium/foregut organoids support the development of an epicardium/myocardium organoid". Nature Communications (2022): https://doi.org/10.1038/s41467-022-34730-7.
    10.1038/s41467-022-34730-7
  7. Ana Rita Gomes; Tiago G. Fernandes; Joaquim M.S. Cabral; Maria Margarida Diogo. "Modeling Rett Syndrome with Human Pluripotent Stem Cells: Mechanistic Outcomes and Future Clinical Perspectives". International Journal of Molecular Sciences (2021): https://doi.org/10.3390/ijms22073751.
    10.3390/ijms22073751
  8. Gomes, Ana Rita; Sangani, Nasim Bahram; Fernandes, Tiago G.; Diogo, M. Margarida; Curfs, Leopold M. G.; Reutelingsperger, Chris P.. "Extracellular Vesicles in CNS Developmental Disorders". International Journal of Molecular Sciences 21 24 (2020): 9428. http://dx.doi.org/10.3390/ijms21249428.
    10.3390/ijms21249428
  9. Gomes, Ana Rita; Fernandes, Tiago G.; Vaz, Sandra H.; Silva, Teresa P.; Bekman, Evguenia P.; Xapelli, Sara; Duarte, Sofia; et al. "Modeling Rett Syndrome With Human Patient-Specific Forebrain Organoids". Frontiers in Cell and Developmental Biology 8 (2020): http://dx.doi.org/10.3389/fcell.2020.610427.
    10.3389/fcell.2020.610427
  10. Amores de Sousa, Miriam C.; Rodrigues, Carlos A. V.; Ferreira, Inês A. F.; Diogo, Maria Margarida; Linhardt, Robert J.; Cabral, Joaquim M. S.; Ferreira, Frederico Castelo. "Functionalization of Electrospun Nanofibers and Fiber Alignment Enhance Neural Stem Cell Proliferation and Neuronal Differentiation". Frontiers in Bioengineering and Biotechnology 8 (2020): http://dx.doi.org/10.3389/fbioe.2020.580135.
    10.3389/fbioe.2020.580135
  11. Branco, Mariana A.; Cabral, Joaquim M.S.; Diogo, Maria Margarida. "From Human Pluripotent Stem Cells to 3D Cardiac Microtissues: Progress, Applications and Challenges". Bioengineering 7 3 (2020): 92. http://dx.doi.org/10.3390/bioengineering7030092.
    10.3390/bioengineering7030092
  12. Silva, Teresa P.; Bekman, Evguenia P.; Fernandes, Tiago G.; Vaz, Sandra H.; Rodrigues, Carlos A. V.; Diogo, Maria Margarida; Cabral, Joaquim M. S.; Carmo-Fonseca, Maria. "Maturation of Human Pluripotent Stem Cell-Derived Cerebellar Neurons in the Absence of Co-culture". Frontiers in Bioengineering and Biotechnology 8 (2020): http://dx.doi.org/10.3389/fbioe.2020.00070.
    10.3389/fbioe.2020.00070
  13. Diogo, Maria. "Dissolvable Microcarriers Allow Scalable Expansion And Harvesting Of Human Induced Pluripotent Stem Cells Under Xeno-Free Conditions". (2019): http://dx.doi.org/10.1002/biot.201800461.
    10.1002/biot.201800461
  14. Dias, T.P.; Fernandes, T.G.; Diogo, M.M.; Cabral, J.M.S.. "Multifactorial modeling reveals a dominant role of wnt signaling in lineage commitment of human pluripotent stem cells". Bioengineering 6 3 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85073387087&partnerID=MN8TOARS.
    10.3390/bioengineering6030071
  15. Branco, M.A.; Cotovio, J.P.; Rodrigues, C.A.V.; Vaz, S.H.; Fernandes, T.G.; Moreira, L.M.; Cabral, J.M.S.; Diogo, M.M.. "Transcriptomic analysis of 3D Cardiac Differentiation of Human Induced Pluripotent Stem Cells Reveals Faster Cardiomyocyte Maturation Compared to 2D Culture". Scientific Reports 9 1 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85068061234&partnerID=MN8TOARS.
    10.1038/s41598-019-45047-9
  16. Diogo, Maria. "Scalable culture of human induced pluripotent cells on microcarriers under xeno-free conditions using single-use vertical-wheel™ bioreactors". (2018): http://dx.doi.org/10.1002/jctb.5738.
    10.1002/jctb.5738
  17. Diogo, Maria. "A scale out approach towards neural induction of human induced pluripotent stem cells for neurodevelopmental toxicity studies". (2018): http://dx.doi.org/10.1016/j.toxlet.2018.05.018.
    10.1016/j.toxlet.2018.05.018
  18. Diogo, Maria. "Towards Multi-Organoid Systems for Drug Screening Applications". (2018): http://dx.doi.org/10.3390/bioengineering5030049.
    10.3390/bioengineering5030049
  19. Diogo, Maria. "Biophysical study of human induced Pluripotent Stem Cell-Derived cardiomyocyte structural maturation during long-term culture". (2018): http://dx.doi.org/10.1016/j.bbrc.2018.03.198.
    10.1016/j.bbrc.2018.03.198
  20. Badenes, S.M.; Fernandes, T.G.; Miranda, C.C.; Pusch-Klein, A.; Haupt, S.; Rodrigues, C.A.V.; Diogo, M.M.; Brüstle, O.; Cabral, J.M.S.. "Long-term expansion of human induced pluripotent stem cells in a microcarrier-based dynamic system". Journal of Chemical Technology and Biotechnology 92 3 (2017): 492-503. http://www.scopus.com/inward/record.url?eid=2-s2.0-84990198014&partnerID=MN8TOARS.
    10.1002/jctb.5074
  21. Rodrigues, G.M.C.; Gaj, T.; Adil, M.M.; Wahba, J.; Rao, A.T.; Lorbeer, F.K.; Kulkarni, R.U.; et al. "Defined and Scalable Differentiation of Human Oligodendrocyte Precursors from Pluripotent Stem Cells in a 3D Culture System". Stem Cell Reports 8 6 (2017): 1770-1783. http://www.scopus.com/inward/record.url?eid=2-s2.0-85019626381&partnerID=MN8TOARS.
    10.1016/j.stemcr.2017.04.027
  22. Badenes, S.M.; Fernandes, T.G.; Cordeiro, C.S.M.; Boucher, S.; Kuninger, D.; Vemuri, M.C.; Diogo, M.M.; Cabral, J.M.S.. "Defined essential 8' medium and vitronectin efficiently support scalable xeno-free expansion of human induced pluripotent stem cells in stirred microcarrier culture systems". PLoS ONE 11 3 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84962476807&partnerID=MN8TOARS.
    10.1371/journal.pone.0151264
  23. Miranda, C.C.; Fernandes, T.G.; Diogo, M.M.; Cabral, J.M.S.. "Scaling up a chemically-defined aggregate-based suspension culture system for neural commitment of human pluripotent stem cells". Biotechnology Journal 11 12 (2016): 1628-1638. http://www.scopus.com/inward/record.url?eid=2-s2.0-85003042306&partnerID=MN8TOARS.
    10.1002/biot.201600446
  24. Badenes, S.M.; Fernandes, T.G.; Rodrigues, C.A.V.; Diogo, M.M.; Cabral, J.M.S.. "Microcarrier-based platforms for in vitro expansion and differentiation of human pluripotent stem cells in bioreactor culture systems". Journal of Biotechnology 234 (2016): 71-82. http://www.scopus.com/inward/record.url?eid=2-s2.0-84980371010&partnerID=MN8TOARS.
    10.1016/j.jbiotec.2016.07.023
  25. Miranda, C.C.; Fernandes, T.G.; Pascoal, J.F.; Haupt, S.; Brüstle, O.; Cabral, J.M.S.; Diogo, M.M.. "Spatial and temporal control of cell aggregation efficiently directs human pluripotent stem cells towards neural commitment". Biotechnology Journal 10 10 (2015): 1612-1624. http://www.scopus.com/inward/record.url?eid=2-s2.0-84943363190&partnerID=MN8TOARS.
    10.1002/biot.201400846
  26. Rodrigues, G.M.C.; Rodrigues, C.A.V.; Fernandes, T.G.; Diogo, M.M.; Cabral, J.M.S.. "Clinical-scale purification of pluripotent stem cell derivatives for cell-based therapies". Biotechnology Journal 10 8 (2015): 1103-1114. http://www.scopus.com/inward/record.url?eid=2-s2.0-84938806348&partnerID=MN8TOARS.
    10.1002/biot.201400535
  27. Fernandes, T.G.; Duarte, S.T.; Ghazvini, M.; Gaspar, C.; Santos, D.C.; Porteira, A.R.; Rodrigues, G.M.C.; et al. "Neural commitment of human pluripotent stem cells under defined conditions recapitulates neural development and generates patient-specific neural cells". Biotechnology Journal 10 10 (2015): 1578-1588. http://www.scopus.com/inward/record.url?eid=2-s2.0-84943351938&partnerID=MN8TOARS.
    10.1002/biot.201400751
  28. Carmelo, J.G.; Fernandes-Platzgummer, A.; Diogo, M.M.; da Silva, C.L.; Cabral, J.M.S.. "A xeno-free microcarrier-based stirred culture system for the scalable expansion of human mesenchymal stem/stromal cells isolated from bone marrow and adipose tissue". Biotechnology Journal 10 8 (2015): 1235-1247. http://www.scopus.com/inward/record.url?eid=2-s2.0-84938992877&partnerID=MN8TOARS.
    10.1002/biot.201400586
  29. Fernandes-Platzgummer, A.; Diogo, M.M.; Lobato da Silva, C.; Cabral, J.M.S.. "Maximizing mouse embryonic stem cell production in a stirred tank reactor by controlling dissolved oxygen concentration and continuous perfusion operation". Biochemical Engineering Journal 82 (2014): 81-90. http://www.scopus.com/inward/record.url?eid=2-s2.0-84889596268&partnerID=MN8TOARS.
    10.1016/j.bej.2013.11.014
  30. Rodrigues, G.M.C.; Matos, A.F.S.; Fernandes, T.G.; Rodrigues, C.A.V.; Peitz, M.; Haupt, S.; Diogo, M.M.; Brüstle, O.; Cabral, J.M.S.. "Integrated Platform for Production and Purification of Human Pluripotent Stem Cell-Derived Neural Precursors". Stem Cell Reviews and Reports 10 2 (2014): 151-161. http://www.scopus.com/inward/record.url?eid=2-s2.0-84897385766&partnerID=MN8TOARS.
    10.1007/s12015-013-9482-z
  31. Meli, L.; Barbosa, H.S.C.; Hickey, A.M.; Gasimli, L.; Nierode, G.; Diogo, M.M.; Linhardt, R.J.; Cabral, J.M.S.; Dordick, J.S.. "Three dimensional cellular microarray platform for human neural stem cell differentiation and toxicology". Stem Cell Research 13 1 (2014): 36-47. http://www.scopus.com/inward/record.url?eid=2-s2.0-84899847797&partnerID=MN8TOARS.
    10.1016/j.scr.2014.04.004
  32. Fernandes, T.G.; Rodrigues, C.A.V.; Diogo, M.M.; Cabral, J.M.S.. "Stem cell bioprocessing for regenerative medicine". Journal of Chemical Technology and Biotechnology 89 1 (2014): 34-47. http://www.scopus.com/inward/record.url?eid=2-s2.0-84897050716&partnerID=MN8TOARS.
    10.1002/jctb.4189
  33. Madeira, C.; Rodrigues, C.A.V.; Reis, M.S.C.; Ferreira, F.F.C.G.; Correia, R.E.S.M.; Diogo, M.M.; Cabral, J.M.S.. "Nonviral gene delivery to neural stem cells with minicircles by microporation". Biomacromolecules 14 5 (2013): 1379-1387. http://www.scopus.com/inward/record.url?eid=2-s2.0-84877778485&partnerID=MN8TOARS.
    10.1021/bm400015b
  34. Barbosa, Helder S. C.; Fernandes, Tiago G.; Dias, Tiago P.; Diogo, Maria Margarida; Cabral, Joaquim M. S.. "New Insights into the Mechanisms of Embryonic Stem Cell Self-Renewal under Hypoxia: A Multifactorial Analysis Approach". Plos One 7 6 (2012):
    10.1371/journal.pone.0038963
  35. Ribeiro, Sofia; Mairhofer, Juergen; Madeira, Catarina; Diogo, Maria Margarida; da Silva, Claudia Lobato; Monteiro, Gabriel; Grabherr, Reingard; Cabral, Joaquim M.. "Plasmid DNA Size Does Affect Nonviral Gene Delivery Efficiency in Stem Cells". Cellular Reprogramming 14 2 (2012): 130-137.
    10.1089/cell.2011.0093
  36. Diogo, Maria Margarida; da Silva, Claudia Lobato; Cabral, Joaquim M. S.. "Separation technologies for stem cell bioprocessing". Biotechnology and Bioengineering 109 11 (2012): 2699-2709.
    10.1002/bit.24706
  37. Rodrigues, Carlos A. V.; Diogo, Maria Margarida; da Silva, Claudia Lobato; Cabral, Joaquim M. S.. "Microcarrier expansion of mouse embryonic stem cell-derived neural stem cells in stirred bioreactors". Biotechnology and Applied Biochemistry 58 4 (2011): 231-242.
    10.1002/bab.37
  38. Fernandes-Platzgummer, Ana; Diogo, Maria M.; Baptista, Ricardo P.; da Silva, Claudia Lobato; Cabral, Joaquim M. S.. "Scale-Up of Mouse Embryonic Stem Cell Expansion in Stirred Bioreactors". Biotechnology Progress 27 5 (2011): 1421-1432.
    10.1002/btpr.658
  39. Rodrigues, Carlos A. V.; Fernandes, Tiago G.; Diogo, Maria Margarida; da Silva, Claudia Lobato; Cabral, Joaquim M. S.. "Stem cell cultivation in bioreactors". Biotechnology Advances 29 6 (2011): 815-829.
    10.1016/j.biotechadv.2011.06.009
  40. Fernandes, T.G.; Barbosa, H.S.C.; Diogo, M.M.; Cabral, J.M.S.; Dordick, J.S.. "Stem cell microarrays as novel systems for high-throughput screening applications". Bio Tech International 22 2 (2010): 16-18. http://www.scopus.com/inward/record.url?eid=2-s2.0-79953314506&partnerID=MN8TOARS.
  41. Fernandes, Tiago G.; Diogo, Maria Margarida; Fernandes-Platzgummer, Ana; da Silva, Claudia Lobato; Cabral, Joaquim M. S.. "Different stages of pluripotency determine distinct patterns of proliferation, metabolism, and lineage commitment of embryonic stem cells under hypoxia". Stem Cell Research 5 1 (2010): 76-89.
    10.1016/j.scr.2010.04.003
  42. Rodrigues, Carlos A. V.; Diogo, Maria Margarida; da Silva, Claudia Lobato; Cabral, Joaquim M. S.. "Hypoxia Enhances Proliferation of Mouse Embryonic Stem Cell-Derived Neural Stem Cells". Biotechnology and Bioengineering 106 2 (2010): 260-270.
    10.1002/bit.22648
  43. Fernandes, Tiago G.; Kwon, Seok Joon; Bale, Shyam Sundhar; Lee, Moo-Yeal; Diogo, Maria Margarida; Clark, Douglas S.; Cabral, Joaquim M. S.; Dordick, Jonathan S.. "Three-Dimensional Cell Culture Microarray for High-Throughput Studies of Stem Cell Fate". Biotechnology and Bioengineering 106 1 (2010): 106-118.
    10.1002/bit.22661
  44. Fernandes, T.G.; Fernandes-Platzgummer, A.M.; da Silva, C.L.; Diogo, M.M.; Cabral, J.M.S.. "Kinetic and metabolic analysis of mouse embryonic stem cell expansion under serum-free conditions". Biotechnology Letters 32 1 (2009): 171-179. http://www.scopus.com/inward/record.url?eid=2-s2.0-72249097517&partnerID=MN8TOARS.
    10.1007/s10529-009-0108-0
  45. Fernandes, Tiago G.; Diogo, Maria Margarida; Clark, Douglas S.; Dordick, Jonathan S.; Cabral, Joaquim M. S.. "High-throughput cellular microarray platforms: applications in drug discovery, toxicology and stem cell research". Trends in Biotechnology 27 6 (2009): 342-349.
    10.1016/j.tibtech.2009.02.009
  46. Diogo, M.M.; Henrique, D.; Cabral, J.M.S.. "Optimization and integration of expansion and neural commitment of mouse embryonic stem cells". Biotechnology and Applied Biochemistry 49 2 (2008): 105-112. http://www.scopus.com/inward/record.url?eid=2-s2.0-38749092143&partnerID=MN8TOARS.
    10.1042/BA20070011
  47. Fernandes, A. M.; Fernandes, T. G.; Diogo, M. M.; da Silva, C. Lobato; Henrique, D.; Cabral, J. M. S.. "Mouse embryonic stem cell expansion in a microcarrier-based stirred culture system". Journal of Biotechnology 132 2 (2007): 227-236.
    10.1016/j.jbiotec.2007.05.031
  48. Passarinha, L.A.; Diogo, M.M.; Queiroz, J.A.; Monteiro, G.A.; Fonseca, L.P.; Prazeres, D.M.F.. "Production of ColE1 type plasmid by Escherichia coli DH5a cultured under nonselective conditions". Journal of Microbiology and Biotechnology 16 1 (2006): 20-24. http://www.scopus.com/inward/record.url?eid=2-s2.0-32944454986&partnerID=MN8TOARS.
  49. Moreira, K.A.; Diogo, M.; Prazeres, D.M.; De Lima Filho, J.L.; Figueiredo Porto, A.L.. "Purification of plasmid (pVaxLacZ) by hydrophobic interaction chromatography". Brazilian Archives of Biology and Technology 48 SPEC. ISS. (2005): 113-117. http://www.scopus.com/inward/record.url?eid=2-s2.0-27944448818&partnerID=MN8TOARS.
  50. Diogo, M. M.; Queiroz, J. A.; Prazeres, D. M. F.. "Chromatography of plasmid DNA". Journal of Chromatography A 1069 1 (2005): 3-22.
    10.1016/j.chroma.2004.09.050
  51. Trindade, I. P.; Diogo, M. M.; Prazeres, D. M. F.; Marcos, J. C.. "Purification of plasmid DNA vectors by aqueous two-phase extraction and hydrophobic interaction chromatography". Journal of Chromatography A 1082 2 (2005): 176-184.
    10.1016/j.chroma.2005.05.079
  52. Diogo, M.M.; Prazeres, D.M.F.; Pinto, N.G.; Queiroz, J.A.. "Hydrophobic interaction chromatography of homo-oligonucleotides on derivatized Sepharose CL-6B: Using and relating two different models for describing the effect of salt and temperature on retention". Journal of Chromatography A 1006 1-2 (2003): 137-148. http://www.scopus.com/inward/record.url?eid=2-s2.0-0042848639&partnerID=MN8TOARS.
    10.1016/S0021-9673(03)00918-X
  53. Diogo, M.M.; Queiroz, J.A.; Prazeres, D.M.F.. "Assessment of purity and quantification of plasmid DNA in process solutions using high-performance hydrophobic interaction chromatography". Journal of Chromatography A 998 1-2 (2003): 109-117. http://www.scopus.com/inward/record.url?eid=2-s2.0-0038392599&partnerID=MN8TOARS.
    10.1016/S0021-9673(03)00618-6
  54. Diogo, M.M.; Queiroz, J.A.; Prazeres, D.M.F.. "Hydrophobic interaction chromatography of homo-oligonucleotides on derivatized Sepharose CL-6B Application of the solvophobic theory". Journal of Chromatography A 944 1-2 (2002): 119-128. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037168964&partnerID=MN8TOARS.
    10.1016/S0021-9673(01)01388-7
  55. Diogo, M.M.; Queiroz, J.A.; Prazeres, D.M.. "Studies on the retention of plasmid DNA and Escherichia coli nucleic acids by hydrophobic interaction chromatography.". Bioseparation 10 4-5 (2001): 211-220. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035554023&partnerID=MN8TOARS.
    10.1023/A:1016361721316
  56. Diogo, M. M.; Ribeiro, S. C.; Queiroz, J. A.; Monteiro, G. A.; Tordo, N.; Perrin, P.; Prazeres, D. M. F.. "Production, purification and analysis of an experimental DNA vaccine against rabies". Journal of Gene Medicine 3 6 (2001): 577-584.
    10.1002/jgm.218
  57. Diogo, M.M.; Queiroz, J.A.; Monteiro, G.A.; Martins, S.A.M.; Ferreira, G.N.M.; Prazeres, D.M.F.. "Purification of a cystic fibrosis plasmid vector for gene therapy using hydrophobic interaction chromatography". Biotechnology and Bioengineering 68 5 (2000): 576-583. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034608587&partnerID=MN8TOARS.
    10.1002/(SICI)1097-0290(20000605)68:5<576::AID-BIT13>3.0.CO;2-5
  58. Diogo, M.M.; Ribeiro, S.; Queiroz, J.A.; Monteiro, G.A.; Perrin, P.; Tordo, N.; Prazeres, D.M.F.. "Scale-up of hydrophobic interaction chromatography for the purification of a DNA vaccine against rabies". Biotechnology Letters 22 17 (2000): 1397-1400. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033799808&partnerID=MN8TOARS.
    10.1023/A:1005665003375
  59. Diogo, M.M.; Silva, S.; Cabral, J.M.S.; Queiroz, J.A.. "Hydrophobic interaction chromatography of Chromobacterium viscosum lipase on polypropylene glycol immobilised on Sepharose". Journal of Chromatography A 849 2 (1999): 413-419. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033062863&partnerID=MN8TOARS.
    10.1016/S0021-9673(99)00619-6
  60. Diogo, M. M.; Queiroz, J. A.; Monteiro, G. A.; Prazeres, D. M. F.. "Separation and analysis of plasmid denatured forms using hydrophobic interaction chromatography". Analytical Biochemistry 275 1 (1999): 122-124.
    10.1006/abio.1999.4297
  61. Diogo, M.M.; Cabral, J.M.S.; Queiroz, J.A.. "Preliminary study on hydrophobic interaction chromatography of Chromobacterium viscosum lipase on polypropylene glycol immobilized on Sepharose". Journal of Chromatography A 796 1 (1998): 177-180. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032512744&partnerID=MN8TOARS.
    10.1016/S0021-9673(97)01059-5
Journal issue
  1. Joaquim MS Cabral, Cláudia Lobato da Silva, and Maria Margarida Diogo. "Stem Cell Bioprocessing and Manufacturing". Bioengineering (2020):
Preface / Postscript
  1. Cabral, J.M.S.; De Silva, C.L.; Chase, L.G.; Diogo, M.M.. "Introduction". 2016.
    10.1016/B978-0-444-63265-4.02001-X
Thesis / Dissertation
  1. Diogo, Maria Margarida. "Development of hydrophobic interaction chromatography processes for analysis and purification of plasmid DNA vectors for gene therapy and DNA vaccination". PhD, Universidade de Lisboa Instituto Superior Técnico, 2004.
  2. Diogo, Maria Margarida. "Purificação de plasmídeos para terapia génica por cromatografia de interacção hidrofóbica". Master, Universidade de Lisboa Instituto Superior Técnico, 1999.

Intellectual property

Patent
  1. Diogo, Maria Margarida. 2007. "Purification of Plasmid DNA by Hydrophobic Interaction Chromatography". United States.
    Granted/Issued
  2. Diogo, Maria Margarida. 2003. "Processo para produção e purificação de DNA plasmídico".
Provisional application for patent
  1. 2024. "Novel Platform to Generate Innervated Human Heart Organoids: A Robust and Stepwise Protocol/Methodology".
    Protected
  2. 2021. "Método para o desenvolvimento de linhas de células estaminais".
    Protected
  3. 2021. "Methods of cardiomyocyte production".
    Protected
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2022/12/19 Cardiac organoids as a tool for disease modeling and drug discovery Kick-off meeting of the Associate Laboratory i4HB
Associate Laboratory i4HB (Lisboa, Portugal)
2022/10/17 Human induced pluripotent stem cells as a tool for modeling Rett Syndrome Round Table: Advances in Rett Syndrome research in Portugal, organized by Epileptogenesis and Epilepsy Network (Horizon 2020 EU-funded Twinning action) and ANPAR (Associação Nacional de Pais e Amigos Rett)
FMUL (Lisboa, Portugal)
2020/10 Engineering region-specific brain organoids from human induced pluripotent stem cells for disease modeling of Rett Syndrome (RTT) 6th Session IST - MedNetworking
IEEE-IST Engineering in Medicine and Biology Society (EMBS) Student Chapter (Online, Portugal)
2019/12/11 Engineering of Forebrain Organoids from Human Induced Pluripotent Stem Cells for Modeling of Rett Syndrome (RTT) 7th International Conference on Stem Cell Engineering 2019
Society for Biological Engineering (Barcelona, Spain)
2019/10 Engineering region-specific brain organoids from human induced pluripotent stem cells for disease modeling of Rett syndrome 11th Meeting of the Portuguese Society for Stem Cells and Cell Therapies (SPCE-TC)
SPCE-TC (Lisboa, Portugal)
2019/07 Bioprocessing Strategies as Tools to Boost the Application of Human Induced Pluripotent Stem Cells for Disease Modeling and Toxicology Assays XXII National Bioprocesses Symposium, XIII Enzymatic Hydrolysis of Biomass Symposium
(Uberlândia, Brazil)
2019/04 Bioengineering Strategies for Differentiation of Human Induced Pluripotent Stem Cells - Applications in Disease Modeling and Toxicology Assays CEDOC Seminars
CEDOC (Lisboa, Portugal)
2019/03 Bioprocessing Strategies as Tools to Boost the Application of Human Induced Pluripotent Stem Cells for Disease Modeling and Toxicology Assays Stem Cell Bioprocessing Seminar of the Discoveries Center for Regenerative and Precision Medicine
(Londres, United Kingdom)
2018/12 Development and Characterization of Brain Region-Specific Organoids from Human Induced Pluripotent Stem Cells for Modelling of Rett Syndrome. 6th International Conference on Stem Cell Engineering
Society for Biological Engineering (Los Angeles, United States)
2018/12 Transcriptomic analysis of 3D Cardiac Differentiation of Human Induced Pluripotent Stem Cells Reveals Faster Maturation Compared to 2D Culture. 6th International Conference on Stem Cell Engineering
Society for Biological Engineering (Los Angeles, United States)
2018/10 Cell Models for Cardiotoxicity Studies Annual Meeting of Associação Portuguesa de Intervenção Cardiovascular (APIC)
APIC (Troia, Portugal)
2017/04 Bioengineering Strategies for Neural Induction of Human Induced Pluripotent Stem Cells - Applications in Neural Disease Modelling and NeuroToxicology Assays Jornadas de Biotecnologia, Universidade da Beira Interior
Universidade da Beira Interior (Covilhã, Portugal)
2017/01 Xeno-free Production and Recovery of Human Induced Pluripotent Stem Cells using Synthetic Dissolvable Microcarriers. Scale-up and Manufacturing of Cell-based Therapies V
Engineering Conferences International (San Diego, CA, United States)
2016/11 Human Pluripotent Stem Cells – From Fundaments to Applications in Regenerative Medicine, Disease Modeling and Drug Screening Stem Cell Symposium: A closer look at stem cell based therapies
Universidade de Lisboa, Faculdade de Farmácia (Lisboa, Portugal)
2016/11 Bioengineering strategies for neural induction of human induced pluripotent stem cells: applications in neural disease modelling and neurotoxicology assays Brain without Borders
SPCE-TC (Coimbra, Portugal)
2016/10 Scaling-up a Chemically-Defined Aggregate-Based Suspension Culture System for Neural Commitment of Human Induced Pluripotent Stem Cells 5th International Conference on Stem Cell Engineering
Society for Biological Enginering (Toronto, Canada)
2016/04 Platforms for Derivation and Enrichment of Human Pluripotent Stem Cell-Derived Cardiomyocytes Monthly Conference of Rede Saúde of Universidade de Lisboa on the topic of “Medicina Regenerativa e Terapia Celular
Rede Saúde (Lisboa, Portugal)
2015/07 Integrated Platform for Derivation and Enrichment of Human Pluripotent Stem Cell-Derived Cardiomyocytes 8th Edition Santa Marta Lisbon Summer Meeting
Santa Marta Hospital (Lisboa, Portugal)
2015/01 Temporal and spatial control of the neural commitment of human pluripotent stem cells as suspension aggregates Scale-up and Manufacturing of Cell-Based Therapies III
Engineering Conferences International (San Diego, United States)
2014/01 Scalable expansion of human induced pluripotent stem cells in xeno-free microcarriers. Scale-up and Manufacturing of Cell-Based Therapies III
Engineering Conferences International (San Diego, United States)
2013/05 Evaluation of Microcarrier-based Suspension Cultures for Human Induced Pluripotent Stem Cells 1st National Meeting of Biotechnology Students
Universidade da Beira Interior (Covilhã, Portugal)
2013 Evaluation of microcarrier-based suspension cultures for human induced pluripotent stem cells 8th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies
SPCE-TC (Faro, Portugal)
2013 Integrated platform for production and purification of pluripotent stem cell derived neural precursors MicroBiotec'13
(Aveiro, Portugal)
2012/09 Design and operation of a bioreactor system for the expansion of mouse embryonic stem cell-derived neural stem cells on microcarriers. ESBES - 9th European Symposium on Biochemical Engineering Science
European Society of Biochemical Engineering - ESBES (Istambul, Turkey)
2010/05 Multi-scale Strategies for Embryonic Stem Cell Culture Invites Seminar at the Centre for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnique Institute (RPI)
Centre for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnique Institute (RPI) (Troy - Albany, United States)
2010 Estratégias Multi-Escala para a Cultura de Células Estaminais Embrionárias Seminários do Centro de Malária e Doenças Tropicais
(Lisboa, Portugal)
2001 Produção e Purificação de Plasmídeos para Terapia Génica e Vacinas de DNA Jornadas nacionais de Química industrial
Universidade da Beira Interior (Covilhã, Portugal)

Supervision

Thesis Title
Role
Degree Subject (Type)
Institution / Organization
2023/01/01 - Current Development of innervated cardiac organoids from human induced pluriptent stem cells
Supervisor
Universidade de Lisboa Instituto Superior Técnico, Portugal
2022/02/01 - Current Modelling Rett syndrome with 3D cardiac models derived from patient-specific human induced pluripotent stem cells
Supervisor
Biomedical Engineering and Biophysics (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
2018/03 - Current Bioengineering of hyaline articular cartilage from human induced pluripotent stem cells (hiPSC) for disease modeling and drug screening of Osteoarthritis.
Supervisor
Bioengineering: Cellular Therapies and Regenerative Medicine (PhD)
2021/05/01 - 2025/04/30 Modelling Rett Syndrome with brain organoids derived from patient-specific human induced pluripotent stem cells for personalized medicine
Supervisor
Bioengenharia (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2022/03/07 - 2022/12 Using novel 3D Heart Organoids derived from human induced pluripotent stem cells (hiPSCs) for Cardiac Toxicity Studies during Heart Development
Supervisor
Ciências de Engenharia - Engenharia Biomédica (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2018 - 2022/07 3D Cellular Microarray Platform for human pluripotent stem cell culture and toxicology screenings.
Co-supervisor
Bioengineering: Cellular Therapies and Regenerative Medicine (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2018 - 2022/06 Chromosome 6 replacement in Human Embryonic Stem Cells (hESCs).
Co-supervisor
Bioengineering: Cellular Therapies and Regenerative Medicine (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2017/02 - 2021/11/02 Engineering region-specific brain organoids from human induced pluripotent stem cells for disease modeling of Rett syndrome.
Supervisor
Bioengineering: Cellular Therapies and Regenerative Medicine (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2017/01/01 - 2021/03/19 Organoid Engineering for Production of 3D Cardiovascular Microtissues from Human Induced Pluripotent Stem Cells for Cardiotoxicity Assays
Supervisor
Bioengineering Systems (MIT-Portugal) (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2017/01 - 2021/03/19 Development of Human Pluripotent Stem Cell-derived Cardiovascular Organoid Microtissues for Cardiotoxicity Screening.
Supervisor
Bioengineering: MIT Portugal programm (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2016 - 2020/05 Identification of novel noncoding genetic variants with functional impact in hypertrophic cardiomyopathy
Co-supervisor
Bioengineering: Cellular Therapies and Regenerative Medicine (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2015 - 2020/01 Three-dimensional culture systems for the Study of human pluripotent stem cells: Microarrays and Spheroids
Co-supervisor
Bioengineering: MIT-Portugal Program (PhD)
Universidade de Lisboa Instituto Superior Técnico Campus Taguspark, Portugal
2016 - 2017/05 Bioprocessing of Human Pluripotent Stem Cell Derived Neural Cells for Regenerative Medicine Applications.
Co-supervisor
Biotechnology (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2014 - 2016/05 Integrated Platform for Expansion and Controlled Differentiation of Human Pluripotent Stem Cells (hPSC) in a Xeno-free chemically defined Suspension System.
Co-supervisor
Biotechnology and Biosciences (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2014 - 2016/05 Understanding Signaling Dynamics in Human Pluripotent Stem Cells: a Systems Biology Approach
Co-supervisor
Biotechnology and Biosciences (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2005 - 2011/12 Bioreactor Culture Systems for the Expansion and Neural Commitment of Mouse Embryonic Stem Cells
Co-supervisor
Bioengineering: MIT-Portugal Program (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2005 - 2011/09 Design and operation of bioreactor systems for the expansion and controlled neural differentiation of stem cells
Co-supervisor
Bioengineering: MIT-Portugal program (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal

Event organisation

Event name
Type of event (Role)
Institution / Organization
2022/01/14 - Current Organization of the seminar "Neurodegenerative Diseases", in the context of Rede Saúde, 14th January 2022. (2022/01/14)
Seminar (Co-organisor)
Universidade de Lisboa, Portugal
2019/09 - Current Responsible for communication activities in the context of "Microrganism Day" at Instituto Superior Técnico (2019)
Exhibition (Member of the Organising Committee)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2019/05 - Current Coordination of the participation of the Department of Bioengineering in the outreach event "Keep in touch". This is an annual event organized at Instituto Superior Técnico during which Técnico alumni and their families come to Técnico to visit the laboratory facilities of the different departaments. (2019/05)
Other (Co-organisor)
2019/01/01 - Current Coordination of the organization of annual outreach event "Laboratórios Abertos DBE". During this event, the Departament of Bioengineering of Instituto Superior Técnico welcomes every year more than 700 students from Portuguese high-schools for presenting the research activities and the teaching offers of this department. (2003)
Other (President of the Organising Committee)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2017/05/04 - Current Co-chair of the 4th Annual Conference of redeSaúde, integrated in the 3rd Innovation Week of Universidade de Lisboa, Reitoria da Universidade de Lisboa, 4th of May 2017 (Co-chaired with Ana M Sebastião, Faculdade de Medicina of Universidade de Lisboa and IMM). (2017/05/04)
2013/04 - Current Member of the scientific and organizing committee of the 1st International Advanced Course on Regenerative Medicine Manufacturing, Tavira, Algarve, Portugal co-organized by Instituto Superior Técnico (PT), Loughborough University (UK) and Georgia Institute of Technology (US), Tavira, Portugal, April 2013. (2013/04)
Workshop (Member of the Organising Committee)
2009/04/29 - 2009/04/30 Member of the Organizing committee of the 4th International Meeting of SPCE-TC (2009 - 2009)
Conference (Member of the Organising Committee)
Universidade de Lisboa Instituto Superior Técnico, Portugal

Event participation

Activity description
Type of event
Event name
Institution / Organization
2024/04/04 - Current Lecture entitled "“Engineering Forebrain Organoids from Human Induced Pluripotent Stem Cells for Modeling Rett Syndrome (RTT)” at the 4th Workshop on Neuroengineering: brain-on-a-chip platforms, 4-5 April 2024 | i3S – Instituto de Investigação e Inovação em Saúde
Workshop
4th Workshop on Neuroengineering: brain-on-a-chip platforms
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2021/10/13 - Current Comemoration of the Stem Cell Awarness Day
Seminar
Stem Cell Awarness Day
Ciência Viva, Portugal
2021/07/20 - Current "Ciência Viva no Verão"
Seminar
Ciência Viva no Verão
2018 - Current Regular participation as moderator in sessions of the annual event Semana da Bioengenharia do Técnico organized by the Núcleos de Estudantes of the Department of Biengineering of IST.
Seminar
Semana da Bioengenharia do Técnico
2016 - Current Células Estaminais: Aplicações Clínicas e Famacológicas, Lecture in Laboratórios Abertos do DBE, IST, 2016.
2015 - Current Uma viagem ao mundo das células estaminais, Lecture in Laboratórios Abertos do DBE, IST, 2015.
Seminar
2008 - Current Member of the Organizing committee of the representation of Institute for Biotechnology and Bioengineering in Futurália 2008.
2008 - Current Member of the Organizing committee of the representation of Institute for Biotechnology and Bioengineering in Forum Ciência Viva 2008.
2022/02 - 2022/02 Participation in the activity - Isto é Técnico - organized by Núcleo de Apoio ao Estudante of IST (NAPE) with an online clarification session about the Bolonha MSc in Bioengineering: Regenerative and Precision Medicine (February 2022).
Seminar
Isto é Técnico
2020/07 - 2020/07 Participation in the activity - Isto é Técnico - organized by Núcleo de Apoio ao Estudante of IST (NAPE) with an online clarification session about the Integrated MSc in Biomedical Engineering (July 2020).
Seminar
Isto é Técnico

Jury of academic degree

Topic
Role
Candidate name (Type of degree)
Institution / Organization
2023/12 Uncovering the neurogenic potential of cannabinoids upon adult neural stem modulation: Cannabidivarin as a novel modulator of adult neurogenesis
(Thesis) Arguer
Diogo Miguel da Palma Lourenço (PhD)
Universidade de Lisboa Faculdade de Medicina, Portugal
2023/01 Modulation and Initiation of Movement by Proprioceptors in Drosophila melanogaster
(Thesis) Arguer
Alexandra Martins de Medeiros Vieira da Silva (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2022/10 Cerebellar organoids derived from hiPSCs to model Angelman syndrome
(Thesis) Arguer
Carina Sofia Barradas Maranga (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2021/01 Bioprocess development for scalable generation of functional liver microtissues/organoids from human pluripotent stem cells
(Thesis) Arguer
Saeed Abbasalizadeh (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2020/10 Tumor microenvironment models: ex vivo, in vitro, and in silico approaches to address targeted therapies
(Thesis) Main arguer
Ana Luísa Pécurto Cartaxo (PhD)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2020/10 Streamlining upstream processing of Complex Biopharmaceuticals
(Thesis) Arguer
Marcos de Sousa (PhD)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2018/12 Platelet lysates-based hydrogels for the development of 3d models for bone cancer
(Thesis) Main arguer
Cátia Filipa Rodrigues Monteiro (Master)
Universidade de Aveiro, Portugal
2018/12 Targeting mitochondria-nucleus communication to improve aging-impaired neurogenesis
(Thesis) Main arguer
Márcia Filipa Freire Dias da Costa (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2018/11 Differences in AD astrocyte phenotypes and responses to microglial-derived cytokines
(Thesis) Main arguer
Sofia Gravanita Ferreira (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2018/09 Engineering human in vitro cardiac tissue models for preclinical research
(Thesis) Arguer
Bernardo Martins da Cunha Abecasis (PhD)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2017/11 Assessment of hiPSC derived cardiomyocytes maturation in extended culture by analysis of alternative splicing expression patterns
(Thesis) Main arguer
Rodrigo Paiva Gonçalves (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
2015/11 Synaptic dysfunction in early encephalopaties: from genes to function
(Thesis) Arguer
Ana Sofia Temudo Duarte António (PhD)
Universidade de Lisboa Faculdade de Medicina, Portugal
2014/09 Nuclear and mitochondrial control of the apoptosis machinery regulates neural stem cell fate
(Thesis) Arguer
Joana Mafalda Rodrigues Xavier (PhD)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2014/02 The role of metabolism and mitochondrial function in embryonic stem cells
(Thesis) Main arguer
Ana Sofia de Jesus Rodrigues (PhD)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2012/09 Cues for Cancer Stem Cells Origin
(Thesis) Main arguer
Cátia Sofia Vicente Gomes (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2011/11 Gene Delivery to Neural Stem Cells using Minicircles and Plasmids without CpG motifs
(Thesis) Main arguer
Mónica Reis (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
2010/06 Mitochondria modulate pluripotency in human Embryonic Stem Cells
(Thesis) Main arguer
Sandra Filipa Tavares Varum (PhD)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2008/11 Efeito do grau de superenrolamento de plamídeos na sua estabilidade estrutural e função biológica
(Thesis) Main arguer
Joana Brissos Magalhães Lima (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal

Association member

Society Organization name Role
2005 - Current Member of the Portuguese Society for Stem Cells and Cell Therapies (SPCE-TC). Member
2024/01/01 - 2025/12/31 Secretary of the Directive Board of the Portuguese Society of Stem Cells and Cell Therapies (SPCE-TC)
2017/01 - 2018/07 Rede Saúde of Universidade de Lisboa Co-Chair
2011 - 2012 Member of the Board of Directors of the Portuguese Society for Stem Cells and Cell Therapies (SPCE-TC) Member of the Board of Directors
2009 - 2010 Member of the Audit Committee of the Portuguese Society for Stem Cells and Cell Therapies (SPCE-TC) Member of the Audit Committee

Committee member

Activity description
Role
Institution / Organization
2019/09 - Current Member of the Scientific Commission of the Integrated MSc in Biological Engineering at Instituto Superior Técnico.
Member
Universidade de Lisboa Instituto Superior Técnico, Portugal
2019/09 - Current Member of the Scientific Commission of the Integrated MSc in Biomedical Engineering at Instituto Superior Técnico.
Member
Universidade de Lisboa Instituto Superior Técnico, Portugal
2019/07 - Current Member of the eventual commission of the Scientific and Pedagogical Councils of Instituto Superior Técnico for implementation of Soft Skills.
Member
Universidade de Lisboa Instituto Superior Técnico, Portugal
2019/01 - Current Coordinator of the outreach activities of the Department of Bioengineering (DBE) of Instituto Superior Técnico including the coordination of DBE’s Editorial Board, responsible for the monthly publication of the DBE’s Newsletter (https://fenix.tecnico.ulisboa.pt/departamentos/dbe/newsletter) and for the DBE’s social networks, and the coordination of the organization of DBE’s annual outreach event “Laboratórios Abertos DBE”.
Coordinator
Universidade de Lisboa Instituto Superior Técnico, Portugal
2014/09/01 - Current Member of the Scientific Commission of the MSc in Biomedical Technologies
Member
Universidade de Lisboa Instituto Superior Técnico, Portugal
2013 - Current Member of the Management Committee of the PhD Program in Bioengineering: Cell Therapies and Regenerative Medicine (http://phdregmedicine.ist.utl.pt/board.html) coordinated by Instituto Superior Técnico and funded by FCT in the 2013 call.
Member
Universidade de Lisboa Instituto Superior Técnico, Portugal
2021 - 2024 Member of Assembleia de Escola of Instituto Superior Técnico (mandate 2021 - 2024).
Member
Universidade de Lisboa Instituto Superior Técnico, Portugal
2023/10/12 - 2023/10/14 Member of the Scientific Commission of the 13th International Conference of the Portuguese Society for Stem Cells and Cellular Therapies (SPCE-TC), joint organization with the European Tissue Repair Society (https://www.etrs.org/) conference, 12-14th October 2023.
Member
2022/03/10 - 2022/03/12 Member of the Scientific Commission of the 12th International Conference of the Portuguese Society for Stem Cells and Cellular Therapies (SPCE-TC), 10-12 March 2022.
Member
Sociedade Portuguesa de Células Estaminais e Terapia Celular, Portugal
2019/01/01 - 2021/12/31 Member of the Executive Board of the Departament of Bioengineering of Instituto Superior Técnico
Member
Universidade de Lisboa Instituto Superior Técnico, Portugal
2014/09/01 - 2015/08/01 Vice-coordinator of the Integrated MSc in Biomedical Engineering at the Department of Bioengineering of Instituto Superior Técnico
Coordinator
Universidade de Lisboa Instituto Superior Técnico, Portugal
2014/09 - 2015/08 Coordinator of mobility studies for the students of the Integrated MSc in Biomedical Engineering at Instituto Superior Técnico.
Coordinator
Universidade de Lisboa Instituto Superior Técnico, Portugal

Conference scientific committee

Conference name Conference host
2023/10/12 - 2023/10/14 13th International Conference of the Portuguese Society for Stem Cells and Cellular Therapies (SPCE-TC), joint organization with the European Tissue Repair Society (https://www.etrs.org/) Coimbra
2022/03/10 - 2022/03/11 12th International Conference of the Portuguese Society for Stem Cells and Cellular Therapies (SPCE-TC) Braga

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2023/11 - Current Human Stem cell models for Rett Syndrome One-week Stem Cell Technologies course for PhD students in Lisbon (Curso de doutoramento (conclusão de unidades curriculares)) Universidade de Lisboa Faculdade de Farmácia, Portugal
2023/11 - Current Human Pluripotent Stem Cell-derived Organoids for In Vitro Modelling of Human Tissues Bioengenharia (Mestrado integrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2022/11 - Current Human Stem cell models for Rett Syndrome One-week Stem Cell Technologies course for PhD students in Lisbon (Curso de doutoramento (conclusão de unidades curriculares)) Universidade de Lisboa Faculdade de Farmácia, Portugal
2022/05 - Current Human Pluripotent Stem Cell-derived Organoids for In Vitro Modelling of Human Tissues for the course of "Tecnologia de Cultura de Células Animais" (Licenciatura) Universidade do Algarve, Portugal
2020/07 - Current Invited Seminar entitled "Advanced in vitro models for target discovery and neuropharmaceutic screening assays", for the PhD Advanced Course "Advances in Neuropharmaceutics", (Organizer: Dora Brites) Faculdade de Farmácia, Universidade de Lisboa, Lisboa, July 2020. PhD Advanced Course “Advances in Neuropharmaceutics” Universidade de Lisboa Faculdade de Farmácia, Portugal
2014/02 - Current Lecturer and coordinator of the module "Stem Cell Engineering" of the PhD program in Bioengineering: Cell Therapies and Regenerative Medicine from 2014 to 2018¿s edition (http://phdregmedicine.ist.utl.pt/). Stem Cell Engineering (Curso de doutoramento (conclusão de unidades curriculares)) Universidade de Lisboa Instituto Superior Técnico, Portugal
2013/09 - Current Lecture entitled "Pluripotent Stem Cells and Regenerative Medicine", for the Elective Course of the Integrated MSc in Medicine (Responsible: Isabel Alcobia), Faculdade de Medicina, Universidade de Lisboa, Lisboa, every academic year since September 2013 Elective Course “Pluripotent Stem Cells and Regenerative Medicine” for the students of the Integrated MSc in Medicine Universidade de Lisboa Faculdade de Medicina, Portugal
2004/01 - Current Teaching of the courses of Cell and Tissue Engineering, Stem Cell Bioengineering, Ethics, Regenerative Medicine, Project in Biomedical Engineering, Pharmaceutical Biotechnology and Bioengineering and Neurengineering to the students of the Integrated MSc in Biomedical Engineering and Integrated MSc in Biological Engineering and to the MSc students of Biotechnology, Bioengineering and Biosciences, Pharmaceutical Engineering and Biomedical Technologies, at Institut Superior Técnico, Universidade de Lisboa. Universidade de Lisboa Instituto Superior Técnico, Portugal
2016/03/12 - 2016/03/16 Lecture entitled "Separation Technologies for Stem Cell Bioprocessing", at the Second International Course on Regenerative Medicine Manufacturing, co-organized by Georgia Institute of Technology (USA), Instituto Superior Técnico (PT) and Loughborough University (UK), Hilton Head Island, USA, March 2016. Second International Course on Regenerative Medicine Manufacturing, March 12-16, 2016, Hilton Head Island, USA, (https://www.regenerativemedicineworkshop.com/short-course) co-organized by Georgia Institute of Technology (US) and IST (PT) (Postgraduate Certificate) Georgia Institute of Technology, United States
2013/04/28 - 2013/05/04 Lectures entitled "Pluripotent Stem Cells" and "Separation Technologies for Stem Cell Bioprocessing" at the First International Advanced Course on Regenerative Medicine Manufacturing, co-organized by Instituto Superior Técnico (PT), Loughborough University (UK) and Georgia Institute of Technology (USA), Tavira, Portugal, April 2013. First International Advanced Course on Regenerative Medicine Manufacturing, Tavira, Algarve, Portugal, by IST (PT) and Georgia Tech (USA) (Outros) Universidade de Lisboa Instituto Superior Técnico, Portugal

Evaluation committee

Activity description
Role
Institution / Organization Funding entity
2020/06 - 2020/09 Member of the Board of Evaluation of FCT individual PhD fellowships the scientific area of Biomedicine - edition of 2020.
Member
Fundação para a Ciência e a Tecnologia
2018/07/02 - 2018/07/04 Member of the bard of evaluation of FCT PhD scholarships in the field of Biomedicine.
Evaluator
Fundação para a Ciência e a Tecnologia - Portugal

Journal scientific committee

Journal title (ISSN) Publisher
2022/01/01 - Current Frontiers in Bioengineering and Biotechnology
2013/07/01 - 2021/08/31 Biotechnology Letters (1573-6776) Springer-Verlag

Mentoring / Tutoring

Topic Student name
2021/09 - Current Tutor for the 1st year students of the degree in Biological Engineering at IST starting in the curricular years of 2021-2022 and 2022-2023. 1st year students of the degree in Biological Engineering at IST
2014/09/01 - 2017/07/31 Tutor for the 1st and 2nd year students of the Integrated MSc in Biomedical Engineering at IST that started in the curricular years of 2014-2015, 2015-2016 and 2018-2019 Groups of Students of the Integrated MSc in Biomedical Engineering
Distinctions

Award

2023 Prémio Crioestaminal & SPCE-TC de Investigação em Medicina Regenerativa
Sociedade Portuguesa de Células Estaminais e Terapia Celular, Portugal
2008 Honourable Mention in Prémio Jovens Investigadores UTL/Deloitte 2008 in the scientific area of Biological Engineering, Biochemistry and Biotechnology, Technical University of Lisbon and Deloitte.

Other distinction

2013 Diploma of excellence in teaching awarded by the Pedagogic Council of Instituto Superior Técnico for the academic years of 2013/2014, 2014/2015, 2015/2016, 2016/2017, 2017/2018, 2018/2019, 2019/2020, and 2020/2021.
Universidade de Lisboa Instituto Superior Técnico, Portugal