???global.info.a_carregar???
Identification

Personal identification

Full name
Alba Orea-Soufi

Citation names

  • Orea-Soufi, Alba

Author identifiers

Ciência ID
6C16-45B1-8301
ORCID iD
0000-0001-9264-6519

Knowledge fields

  • Natural sciences - Biological Sciences - Molecular Biology
  • Medical and Health Sciences - Clinical Medicine - Oncology
  • Natural sciences - Biological Sciences - Biochemistry
  • Natural sciences - Biological Sciences - Cell Biology

Languages

Language Speaking Reading Writing Listening Peer-review
English Upper intermediate (B2) Advanced (C1) Upper intermediate (B2) Advanced (C1) Upper intermediate (B2)
Spanish; Castilian (Mother tongue)
Portuguese Intermediate (B1) Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2) Intermediate (B1)
Education
Degree Classification
2015/10/01 - 2022/07/02
Concluded
Bioquímica, biología molecular y biomedicina (Doctor)
Universidad Complutense de Madrid, Spain
"Papel de la pseudoquinasa Tribales 3 en cáncer de mama: estudios mecanisticos e implicaciones en el pronóstico del subtipo luminal" (THESIS/DISSERTATION)
Cum laude
2014/09/01 - 2015/07/15
Concluded
Bioquímica, biología molecular y biomedicina (Master)
Universidad Complutense de Madrid, Spain
9,61
2010/09/01 - 2014/07/15
Concluded
Bioquímica (Bachelor)
Universidad Complutense de Madrid, Spain
Affiliation

Science

Category
Host institution
Employer
2022/02/07 - Current Postdoc (Research) Universidade do Algarve, Portugal
2015/10/01 - 2021/09/30 Researcher (Research) Universidad Complutense de Madrid, Spain
Projects

Contract

Designation Funders
2022/02/01 - Current Overcoming drug resistance in glioblastoma
PTDC/MED-ONC/4167/2020
Post-doc
Universidade do Algarve, Portugal

Algarve Biomedical Center Research Institute, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2019 - 2021 Mechanism of autophagy-mediated cancer cell death and participation of autophagy associated genes in the control of tumorigenesis
Pi18/00442
Researcher
Universidad Complutense de Madrid, Spain
Gobierno de España
Concluded
2016 - 2019 TRAIN
TRAIN-GA721532
Researcher
European Commission Marie Sklodowska-Curie Actions
Concluded
2016 - 2018 Role of autophagy in cancer: autophagy-mediated cell death in tumoral cells and participation of autophagy regulatory genes in the control of tumorigenesis
PI15/00339
Researcher
Gobierno de España
Concluded
Outputs

Publications

Book chapter
  1. Orea-Soufi, Alba; Dávila, David; Salazar, María; Lorente, Mar; Velasco, Guillermo. Corresponding author: Velasco, Guillermo. "Phosphorylation of FOXO Proteins as a Key Mechanism to Regulate Their Activity". 51-59. Springer New York, 2019.
    10.1007/978-1-4939-8900-3_5
Journal article
  1. Orea-Soufi, Alba; Paik, Jihye; Bragança, José; Donlon, Timothy A.; Willcox, Bradley J.; Link, Wolfgang. Corresponding author: Link, Wolfgang. "FOXO transcription factors as therapeutic targets in human diseases". Trends in Pharmacological Sciences 43 12 (2022): 1070-1084. http://dx.doi.org/10.1016/j.tips.2022.09.010.
    10.1016/j.tips.2022.09.010
  2. Hernández-Quiles, Miguel; Baak, Rosalie; Orea-Soufi, Alba; Borgman, Anouska; den Haan, Suzanne; Sobrevals Alcaraz, Paula; Jongejan, Aldo; et al. Corresponding author: Kalkhoven, Eric. "TRIB3 Modulates PPAR¿-Mediated Growth Inhibition by Interfering with the MLL Complex in Breast Cancer Cells". International Journal of Molecular Sciences 23 18 (2022): 10535. http://dx.doi.org/10.3390/ijms231810535.
    10.3390/ijms231810535
  3. Orea-Soufi, Alba; Castillo-Lluva, Sonia; Salvador-Tormo, Nélida; Martín-Cabrera, Paola; Recuero, Silvia; Gabicagogeascoa, Estíbaliz; Moreno-Valladares, Manuel; et al. "The Pseudokinase TRIB3 Negatively Regulates the HER2 Receptor Pathway and Is a Biomarker of Good Prognosis in Luminal Breast Cancer". Cancers 13 21 (2021): 5307. http://dx.doi.org/10.3390/cancers13215307.
    10.3390/cancers13215307
  4. Salazar, María; Lorente, Mar; Orea-Soufi, Alba; Dávila, David; Erazo, Tatiana; Lizcano, José; Carracedo, Arkaitz; Kiss-Toth, Endre; Velasco, Guillermo. Corresponding author: Velasco, Guillermo. "Oncosuppressive functions of tribbles pseudokinase 3". Biochemical Society Transactions 43 5 (2015): 1122-1126. http://dx.doi.org/10.1042/bst20150124.
    10.1042/bst20150124
Activities

Event participation

Activity description
Type of event
Event name
Institution / Organization
2024/01/26 - 2024/01/26 Participation in congress contribution "the impact of metabolic modulatiors on the viability of glioblastoma cells"
Workshop
ix clinical biochemistry workshop
Sociedade Portuguesa de Bioquímica, Portugal
2021/10/26 - 2021/10/29 Poster presentation "Role of TRIB3 pseudokinase in luminal breast cancer"
Congress
XIX congress of the spanish society of molecular biology
sociedad española de biología celular, Spain
2018/11/06 - 2018/11/08 Poster presentation "Role of TRIB3 pseudokinase in breast cancer development and progression"
Congress
16th ASEICA International Congress
Asociación Española de Investigación sobre el Cáncer, Spain
2018 - 2018 Training seminar on university teaching skills (30 hours)
Workshop
Training seminar on university teaching skills
Gobierno de Espana Ministerio de Educación Cultura y Deporte, Spain
2017/11/15 - 2017/11/17 Participation in congress contribution "Ambra1 regulates epitheliala to mesenchymal transition in squamous cell carcinoma cells through the TGFb pathway"
Congress
2nd NEAR Meeting
sociedad española de autofagia, Spain
2017/11/15 - 2017/11/17 Participation in congress contribution "Ambra1, a novel biomarker of prognosis in human squamous cell carcinoma"
Congress
2nd NEAR Meeting
sociedad española de autofagia, Spain
2017/05/07 - 2017/05/09 Poster presentation "Dual role of TRIB3 pseudokinase in breast cancer development and progression"
Congress
2nd International Symposium on Tribbles and Disease (ISTD 2018)
2017/05/07 - 2017/05/09 Participation in congress contribution "Role of TRIB3 in the regulation of cancer generation, progression and response to therapy"
Congress
2nd International Symposium on Tribbles and Disease (ISTD 2018)
2017/05/07 - 2017/05/09 Participation in congress contribution "Does Tribbles 3 act as an onco-suppressor in prostate cancer cells?"
Congress
2nd International Symposium on Tribbles and Disease (ISTD 2018)
2017/05/07 - 2017/05/09 Participation in congress contribution "Potential role of TRIB3 in the development of hepatocelular carcinoma"
Conference
2nd International Symposium on Tribbles and Disease (ISTD 2018)
2017 - 2017 Course in medical neuro-oncology (8 hours)
Workshop
Course in medical neuro-oncology
grupo español de investigación en neurooncología, Spain
2016/09/05 - 2016/09/08 Poster presentation "Dual role of the pseudokinase TRIB3 in the development of breast "
Congress
XXXIX Congreso de la Sociedad Española de Bioquímica y Biología Molecular
Sociedad Española de Bioquímica y Biología Molecular, Spain
2016/06/12 - 2016/06/15 Participation in congress contribution "Ambra1, a new biomarker in human squamous cell carcinoma"
Congress
1st NEAR Meeting
sociedad española de autofagia, Spain
2016 - 2016 Gas Safety Course in the Laboratory (4.5 hours)
Workshop
Gas Safety Course in the Laboratory
Universidad Complutense de Madrid, Spain
2016 - 2016 Course on proteomics "VII Hands-on Course in Ultrafast Sample Treatment for Proteomic" (20 hours)
Workshop
VII Hands-on Course in Ultrafast Sample Treatment for Proteomic
Associação Científica Proteomass, Portugal
2015/06/28 - 2015/06/29 Participation in congress contribution "Role of Ambra1 in squamous cell carcinoma"
Congress
3rd Meeting of the Spanish Autophagy Group
sociedad española de autofagia, Spain
2015/04/22 - 2015/04/22 Poster presentation "Potential role for the pseudokinase TRIB3 in the modulation of the invasiveness and metastatic ability of tumour cells"
Congress
Meeting Tribbles Pseudokinases. At the crossroads of metabolism, cancer, inmunity and development
2015/04/22 - 2015/04/22 participation in congress contribution ". Dual role of the pseudokinase TRIB3 in the development of breast cancer"
Congress
Meeting Tribbles Pseudokinases. At the crossroads of metabolism, cancer, inmunity and development
2015/04/22 - 2015/04/22 Participation in congress contribution "Tumor suppressor role of TRIB3"
Congress
Meeting Tribbles Pseudokinases. At the crossroads of metabolism, cancer, inmunity and development
2015 - 2015 Prevention of biological risk in research laboratories and animal facilities (4 hours)
Workshop
Prevention of biological risk in research laboratories and animal facilities
Universidad Complutense de Madrid, Spain
2015 - 2015 Animal Experimentation Course (category B; 40 hours)
Workshop
Animal Experimentation Course (category B)
Centro de Estudios Biosanitarios, Spain

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2019 - 2020 Fundamentals of genetic and genomic engineering degree in biology (Bachelor) Universidad Complutense de Madrid, Spain
2019 - 2020 Industrial Biochemistry Degree in Chemical Engineering (Bachelor) Universidad Complutense de Madrid, Spain
2019 - 2020 Biochemistry Degree in Biology (Bachelor) Universidad Complutense de Madrid, Spain
2018 - 2019 biochemistry Degree in Biology (Bachelor) Universidad Complutense de Madrid, Spain
2018 - 2019 Enzyme biotechnology degree in biology (Bachelor) Universidad Complutense de Madrid, Spain
2017 - 2018 Pathology and Clinical Biochemistry degree in biology (Bachelor) Universidad Complutense de Madrid, Spain
2017 - 2018 Fundamentals of Genetic and Genomic Engineering degree in biology (Bachelor) Universidad Complutense de Madrid, Spain
2016 - 2017 Integrated Laboratory of Biochemistry and Molecular Biology 2 Degree in Biochemistry (Bachelor) Universidad Complutense de Madrid, Spain
2015 - 2016 Fundamentals of Genetic and Genomic Engineering degree in biology (Bachelor) Universidad Complutense de Madrid, Spain
2014 - 2015 biochemistry Degree in Biology (Bachelor) Universidad Complutense de Madrid, Spain

Mentoring / Tutoring

Topic Student name
2023 - 2024 Study of the mechanism underlying TRIB2-mediated resistance in glioblastoma Carlos Amenábar
2023 - 2023 impacto do gene TRIB2 no metabolismo energético de glioblastomas Víctor Yassuda
2022 - 2023 Contribution of Tribbles protein family members in glioblastoma cells Letícia Leite
2020 - 2021 Role of TRIB3 in luminal breast cancer migration and invasion Paola Martín
2019 - 2020 Role of TRIB3 in luminal breast cancer therapy response Silvia Recuero
Distinctions

Award

2015 Best record of the master promotion
Universidad Complutense de Madrid, Spain
2014 5th best record of the bachelor promotion
Universidad Complutense de Madrid, Spain