Luis Graca has an MD from the University of Lisbon, Portugal, and a PhD in transplant immunology from the University of Oxford, UK. He developed his post-doctoral research first in Oxford and later at the Institute for Child Health Research in Perth, Australia. He is currently Professor of Immunology and Vice-Dean at the University of Lisbon Medical School, directing a research group in Cellular Immunology at the Instituto de Medicina Molecular. My research's primary focus has been understanding the regulation of immune pathology. I acquired unique expertise with therapeutic monoclonal antibodies (under H. Waldmann) and regulatory T (Treg) cells, which I have used to study human immunology and immune pathology. Recently I made significant contributions related to the regulation of humoral responses in human individuals, and in the pathogenesis of human autoimmunity. I have been exploring the concept that in the same way that specialized inflammatory responses are necessary for optimal immunity, specialized regulatory mechanisms ought to be also present. While probing this concept, I discovered the existence of Foxp3+ iNKT cells and, more recently, T follicular regulatory (Tfr) cells specialized in regulating humoral responses. The recognition of my research has led to invitations to review the field, presentations in major conferences, election to editor-in-chief of the European Federation of Immunology Societies (EFIS) official journal, as well as election as president of the Portuguese Society of Immunology and more recently as president of the Portuguese Medical Sciences Society (the oldest medical society in Europe). Given my expertise in immunology and vaccination, I have been serving as co-chair of the National Advisory Group for COVID-19 Vaccination since 2020, representing the country in meetings of the Strategic Advisory Group on Immunization (SAGE) of the WHO, and National Immunization Technical Advisory Groups (NITAG) of the ECDC. One highlight of my career was the definition of a COVID-19 vaccination plan incorporating the best immunology evidence and transparent public communication, leading to overall population acceptance and broad vaccination coverage, recognized as one of the best vaccination programs in the World. I have been hosting several artists from different countries, including a long-term relationship with Marta de Menezes (www.martademenezes.com), a pioneer in the field of bioart. Artworks developed by different artists in collaboration with Graca's laboratory have been exhibited in major venues worldwide and included in books and articles reviewing the leading edge of science/art collaborations.