Identification
Personal identification
- Full name
- Bruno Miguel Ferreira Gonçalves
Citation names
- GONÇALVES, BRUNO
- Bruno M. F. Goncalves
Author identifiers
- Ciência ID
- 6C1E-F602-0B33
- ORCID iD
- 0000-0002-3137-5329
Telephones
- Mobile phone
-
- 916648867 (Personal)
Websites
- https://www.linkedin.com/in/brunogon%C3%A7alves/ (Professional)
Knowledge fields
- Medical and Health Sciences - Basic Medicine - Medicinal Chemistry
- Exact Sciences - Chemical Sciences
- Medical and Health Sciences - Basic Medicine - Medicinal Chemistry
- Natural sciences - Biological Sciences - Cell Biology
- Medical and Health Sciences - Basic Medicine - Medicinal Chemistry
Languages
Language | Speaking | Reading | Writing | Listening | Peer-review |
---|---|---|---|---|---|
Portuguese (Mother tongue) | |||||
English | Advanced (C1) | Advanced (C1) | Advanced (C1) | Advanced (C1) | Advanced (C1) |
Spanish; Castilian | Intermediate (B1) | Upper intermediate (B2) | Beginner (A1) | Advanced (C1) | Intermediate (B1) |
Education
Degree | Classification | |
---|---|---|
2011/01/01 - 2016/11/16
Concluded
|
Pharmaceutical Sciences, Specialty of Pharmaceutical Chemistry (Doutoramento)
Major in Especialidade: Química Farmacêutica
Faculty of Pharmacy, University of Coimbra, Portugal
" Preparation and Preclinical Evaluation of New Triterpenoid Compounds" (THESIS/DISSERTATION)
|
Passed with Distinction and Honours |
2010/09/15 - 2010/09/15
Concluded
|
Pharmaceutical Sciences Integrated Master (Mestrado integrado)
Faculty of Pharmacy, University of Coimbra, Portugal
"“Topoisomerase I inhibitors: clinical use as anticancer agents”
" (THESIS/DISSERTATION)
|
16.4 out of 20 |
Affiliation
Science
Category Host institution |
Employer | |
---|---|---|
2019/03/01 - Current | Contracted Researcher (Research) | Farm-id - Associação da Faculdade de Farmácia para a Investigação e Desenvolvimento, Portugal |
Faculty of Pharmacy, University of Lisbon, Portugal | ||
2011/01/01 - 2016/11/26 | Researcher (Research) | Faculty of Pharmacy, University of Coimbra, Portugal |
2013/04/01 - 2014/09/30 | Visiting Researcher (Research) | Universitat de Barcelona Facultat de Biologia, Spain |
Universitat de Barcelona Facultat de Biologia, Spain |
Teaching in Higher Education
Category Host institution |
Employer | |
---|---|---|
2022/05/01 - 2023/07/31 | Invited Assistant Professor (University Teacher) | Lusófona University School of Health Sciences and Technologies (ECTS) , Portugal |
2017/03/25 - 2017/03/26 | Invited Assistant (University Teacher) | Faculty of Pharmacy, University of Coimbra, Portugal |
Faculty of Pharmacy, University of Coimbra, Portugal |
Other Careers
Category Host institution |
Employer | |
---|---|---|
2022/11/22 - Current | Técnico Superior (Técnico Superior) | Faculty of Pharmacy, University of Lisbon, Portugal |
2015/05/01 - 2016/04/30 | Técnico Farmacêutico Principal (Técnico Farmacêutico) | Farmácia Vilaça, Portugal |
Farmácia Vilaça, Portugal | ||
2010/09/15 - 2010/12/31 | Técnico Farmacêutico 1 Cl (Técnico Farmacêutico) | Farmácia do Caramulo, Portugal |
Farmácia do Caramulo, Portugal |
Positions / Appointments
Category Host institution |
Employer | |
---|---|---|
2016/06/01 - Current | Director of Research and Development, Research scientist | Chem4Pharma, Portugal |
Chem4Pharma, Portugal |
Projects
Grant
Designation | Funders | |
---|---|---|
2011/01 - 2015/01 | Preparation and preclinical evaluation of new triterpenoid derivatives
SFRH / BD / 69193 / 2010
|
Fundação para a Ciência e a Tecnologia |
Contract
Designation | Funders | |
---|---|---|
2023/01/01 - Current | Exploiting monoterpene indole alkaloid derivatives for overcoming resistance in BRCA-deficient cancers. In silico characterization
of binding modes
2022.05718.PTDC
Researcher
|
Ongoing
|
2021/11/01 - 2022/09/01 | Synthetic valorization of furan based building blocks derived from renewable resources
PTDC/QUI-QOR/32008/2017
Post-doc
Farm-id - Associação da Faculdade de Farmácia para a Investigação e Desenvolvimento, Portugal
|
Associação para a Inovação e Desenvolvimento da FCT
Ongoing
|
2019/03/01 - 2021/08/31 | Tackling multidrug resistance in cancer plant derived lead compounds as P glycoprotein (P gp and breast cancer resistant protein
( modulators and collateral sensitivity agents
PTDC/MED QUI/ 30591 2017
Post-doc
Instituto de Investigação do Medicamento (iMed.ULisboa) Faculdade de Farmácia da Universidade de Lisboa , Portugal
|
Ongoing
|
2016/06/01 - 2019/02/28 | Drugs 2 CAD Treatment of Cancer and Alzheimer diseases discovery of new drugs
Post-doc
Universidade de Coimbra Faculdade de Farmácia, Portugal
|
European Regional Development Fund
Concluded
|
Outputs
Publications
Book chapter |
|
Conference abstract |
|
Conference poster |
|
Journal article |
|
Thesis / Dissertation |
|
Intellectual property
Patent |
|
Activities
Oral presentation
Presentation title | Event name Host (Event location) |
|
---|---|---|
2021/06/14 | ATP binding induces characteristic structural changes in the ABCG2 transport channel | XXVII Encontro Nacional da Sociedade Portuguesa de Química
University of Minho (Braga, Portugal)
|
2021/03/30 | New insights into BCRP efflux mechanism through Molecular Dynamics Simulations | 14º Encontro Nacional de Química Física, 3º Simpósio de Química Computacional
University of Coimbra (Coimbra, Portugal)
|
2020/12/15 | Exploring the efflux and modulation mechanisms of Human ABCG2 through Molecular Dynamics Simulations | COST Action 17104 (STRATAGEM) WG2 Meeting and International Online Symposium em “Synthesis and nanodelivery strategies for new therapeutic tools against Multidrug Resistant Tumours” |
Supervision
Thesis Title Role |
Degree Subject (Type) Institution / Organization |
|
---|---|---|
2023/11/01 - Current | Generation of a library of alkaloid derivatives to overcome drug resistance in cancer
Co-supervisor
|
Master in Medicinal and Biopharmaceutical Chemistry (Master)
Faculty of Pharmacy, University of Lisbon, Portugal
|
2023/10/01 - Current | Development of new indole alkaloid derivatives to target multidrug resistance in cancer
Co-supervisor
|
Master’s degree in Industrial Pharmaceutical Chemistry (Master)
Faculty of Pharmacy, University of Coimbra, Portugal
|
2020/09/21 - 2022/02/25 | Development of new alkaloid derivatives as multidrug resistance reversers in cancer cells.
Co-supervisor of Rita Mestre Vieira
|
Mestrado Química Medicinal e Biofarmacêutica (Master)
Faculty of Pharmacy, University of Lisbon, Portugal
|
2019/10/22 - 2021/02/11 | Generation of a library of diterpene derivatives for restoring antibiotic activity against resistant bacterial strains
Co-supervisor of Bernardo Manuel Moreira Simões Vieira
|
Química Farmacêutica e Terapêutica (Master)
University of Lisbon-Faculty of Pharmacy, Portugal
|
2017/09/20 - 2018/10/11 | Preparation of semisynthetic derivatives of abietane type diterpenes
Co-supervisor of Ana Filipa Teixeira Salvador
|
Mestrado em Química Farmacêutica Industrial (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
|
Event organisation
Event name Type of event (Role) |
Institution / Organization | |
---|---|---|
2019/07/28 - 2019/07/31 | Natural Products in Drug Discovery and Human Health (NatProdDDH) - PSE Meeting Lisbon. (2019/07/28 - 2019/07/31)
Meeting (Member of the Organising Committee)
|
Faculty of Pharmacy, University of Lisbon, Portugal |
Event participation
Activity description Type of event |
Event name Institution / Organization |
|
---|---|---|
2023/07/10 - 2023/07/14 | VERÃO NA ULISBOA; Experimental activity and dissemination towards the high Scholl students
Exhibition
|
Verão na ULisboa
Faculty of Pharmacy, University of Lisbon, Portugal
|
2023/05/30 - 2023/05/30 | DIA ABERTO FFUL; Experimental activity and dissemination towards the High Scholl Students
Exhibition
|
Dia Aberto FFUL
Faculty of Pharmacy, University of Lisbon, Portugal
|
2022/09/30 - 2022/09/30 | NOITE EUROPEIA DOS INVESTIGADORES 2022; Experimental activity and dissemination towards the general public.
Exhibition
|
Noite Europeia dos Investigadores 2022
Lusófona University School of Health Sciences and Technologies (ECTS) , Portugal
|
Jury of academic degree
Topic Role |
Candidate name (Type of degree) Institution / Organization |
|
---|---|---|
2023/12/21 | Amaryllidaceae-type alkaloids as anticancer hit/leads, targeting multidrug resistant cancer cells
(Thesis) Arguer
|
Shirley Arnie dos Reis Sancha (PhD)
Faculty of Pharmacy, University of Lisbon, Portugal
|
2023/06/05 | Development of a small library of natural compounds and derivatives for targeting resistant bacteria
(Thesis) Arguer
|
Carolina de Carvalho Lorga Lamelas (Master)
Faculty of Pharmacy, University of Lisbon, Portugal
|
2022/02/25 | Anticancer Activity of Quinolizidine Alkaloids: Reversal of Multidrug Resistance
Supervisor
|
Rita Mestre Vieira (Master)
Faculty of Pharmacy, University of Lisbon, Portugal
|
2022/01/12 | Plant-derived compounds for targeting multidrug resistance in cancer
(Thesis) Arguer
|
David dos Santos Paulino Cardoso (PhD)
Faculty of Pharmacy, University of Lisbon, Portugal
|
2021/02/01 | Generation of a library of diterpene derivatives for restoring antibiotic activity against resistant bacterial strains
Supervisor
|
Bernardo Manuel Moreira Simões Vieira (Master)
Faculty of Pharmacy, University of Lisbon, Portugal
|
2018/10/11 | Preparation of semisynthetic derivatives of abietane type diterpenes
Supervisor
|
Ana Filipa Teixeira Salvador (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
|
2017/03/03 | Síntese de Triterpenóides Fluorados
(Thesis) Main arguer
|
Mónica Fernanda Freitas Serra (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
|
Ad Hoc journal article review
Journal title (ISSN) | Publisher | |
---|---|---|
2021/08/01 - Current | Cancers (2072-6694) | MDPI-Multidisciplinary Digital Publishing Institute |
2023/12/17 - 2023/12/30 | Phytochemistry Reviews (1568-7767) | Springer |
2023/10/30 - 2023/10/31 | International Journal of Molecular Sciences (1422-0067) | MDPI |
2022/12/30 - 2022/12/31 | Frontiers in Pharmacology (1663-9812) | Frontiers |
2022/10/23 - 2022/10/23 | Biomedical and Biopharmaceutical Research (2182-2360) | ALIES |
2021/09/01 - 2021/09/09 | Evidence Based Complementary and Alternative Medicine (1741-4288) | Hindawi |
2020/12/12 - 2020/12/20 | Molecules (1420-3049) | MDPI |
2020/06/01 - 2020/06/10 | Phytochemistry Reviews (1572-980X) | Springer |
2020/03/01 - 2020/03/10 | Molecules (1420-3049) | MDPI-Multidisciplinary Digital Publishing Institute |
Course / Discipline taught
Academic session | Degree Subject (Type) | Institution / Organization | |
---|---|---|---|
2022/09/01 - 2023/02/28 | Tecnologia farmacêutica II | Integrated Master's in Pharmaceutical Sciences (Mestrado integrado) | Lusófona University School of Health Sciences and Technologies (ECTS) , Portugal |
2022/09/01 - 2023/01/31 | Veiculação de Fármacos | (Mestrado integrado) | Lusófona University School of Health Sciences and Technologies (ECTS) , Portugal |
2022/09/01 - 2023/01/31 | Química Orgânica II | Integrated Master's in Pharmaceutical Sciences (Mestrado integrado) | Lusófona University School of Health Sciences and Technologies (ECTS) , Portugal |
2022/09/01 - 2023/01/31 | Química Medicinal Inorgânica | (Mestrado integrado) | Lusófona University School of Health Sciences and Technologies (ECTS) , Portugal |
2022/09/01 - 2023/01/31 | Química Medicinal Inorgânica | (Licenciatura) | Lusófona University School of Health Sciences and Technologies (ECTS) , Portugal |
2022/04/01 - 2022/06/30 | Cosmetologia | Integrated Master's in Pharmaceutical Sciences (Mestrado integrado) | Lusófona University School of Health Sciences and Technologies (ECTS) , Portugal |
2017/06/03 - 2017/06/03 | Novos processos em Química Farmacêutica Industrial | Master’s degree in Industrial Pharmaceutical Chemistry (Mestrado) | Faculty of Pharmacy, University of Coimbra, Portugal |
Mentoring / Tutoring
Topic | Student name | |
---|---|---|
2022/03/21 - 2022/06/30 | Exploring the Piancatelli Rearrangement of 3-acetamido-5-hydroxymethyl furan | Joana Cabrita Pereira |
2020/10/01 - 2021/01/31 | New diterpene semisynthetic derivatives as MDR reversers | Oliviero Cini |
2019/11/01 - 2020/02/29 | New diterpene semisynthetic derivatives with antibacterial properties | Carlos Rial Cumbrera |
2015/09/20 - 2017/03/03 | Designing and preparation of new BACE 1 inhibitors for Alzheimer’s disease treatment | Mariana Gomes Gonçalves Arelo Manso |
2012/09/20 - 2013/10/31 | Structural Modifications in triterpenoid compounds | Diana Sofia Marques dos Santos |
Other jury / evaluation
Activity description | Institution / Organization | |
---|---|---|
2023/10/13 - 2023/10/13 | Participated as a member of the jury, acting as examiner, in the presentation of the comprehensive review conducted as part of the course "Seminar II" of the Doctorate in Pharmaceutical Sciences, submitted by Bachelor Sara Patricia de Sousa Pereira Moura. | Faculty of Pharmacy, University of Coimbra, Portugal |
2023/06/23 - 2023/06/26 | Poster Evaluation on the 14th iMed.ULisboa Meeting | Faculty of Pharmacy, University of Lisbon, Portugal |
Distinctions
Award
2010 | Award for the 3 best students of each course, for the academic year of 2009 2010 Faculty of Pharmacy, University of Coimbra |
2010 | Scholarship SFRH/BD/ 69193 2010 Fundação para a Ciência e a Tecnologia Ministério da Educação e Ciência |
2008 | Award for the 3 best students of each course, for the academic year of 2007 2008 Faculty of Pharmacy, University of Coimbra |