Curriculum Vitae
Pedro Sousa-Victor
Identification
Personal identification
- Full name
- Pedro Sousa-Victor
Citation names
- Sousa-Victor, Pedro
Author identifiers
- Ciência ID
- 7015-9ABE-E82D
- ORCID iD
- 0000-0002-6521-7839
- Google Scholar ID
- VQ29d4cAAAAJ&hl
Websites
- https://scholar.google.com/citations?user=VQ29d4cAAAAJ&hl=en (Scholar)
- https://imm.medicina.ulisboa.pt/investigation/laboratories/neves-victor-lab/ (Professional)
Languages
| Language | Speaking | Reading | Writing | Listening | Peer-review |
|---|---|---|---|---|---|
| Portuguese (Mother tongue) | |||||
| English | Proficiency (C2) | Proficiency (C2) | Proficiency (C2) | Proficiency (C2) | Proficiency (C2) |
| Spanish; Castilian | Advanced (C1) | Advanced (C1) | Intermediate (B1) | Advanced (C1) | Upper intermediate (B2) |
Education
| Degree | Classification | |
|---|---|---|
|
2008 - 2012
Concluded
|
PhD in Cell and Molecular Biology (Doctorat)
Universitat Pompeu Fabra Departament de Ciences Experimentals i de la Salut, Spain
|
Apte "Cum Laude" |
|
2006 - 2008
Concluded
|
International PhD Program in health and Life Sciences (DEA)
Universitat Pompeu Fabra Departament de Ciences Experimentals i de la Salut, Spain
|
|
|
2000 - 2005
Concluded
|
Química Aplicada (Licenciatura)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
|
15 |
Affiliation
Science
| Category Host institution |
Employer | |
|---|---|---|
| 2019/04 - Current | Principal Investigator (Research) | Instituto de Medicina Molecular, Portugal |
| Instituto de Medicina Molecular, Portugal | ||
| 2013/01 - 2019/02 | Postdoc (Research) | Buck Institute for Research on Aging, United States |
| Buck Institute for Research on Aging, United States | ||
| 2012/04 - 2012/11 | Postdoc (Research) | Universitat Pompeu Fabra Departament de Ciences Experimentals i de la Salut, Spain |
| Universitat Pompeu Fabra Departament de Ciences Experimentals i de la Salut, Spain | ||
| 2008 - 2012/04 | Research Trainee (Research) | Universitat Pompeu Fabra Departament de Ciences Experimentals i de la Salut, Spain |
| Universitat Pompeu Fabra Departament de Ciences Experimentals i de la Salut, Spain | ||
| 2006 - 2008 | Research Trainee (Research) | Centre de Regulació Genòmica, Spain |
| Centre de Regulació Genòmica, Spain | ||
| 2005 - 2006 | Research Trainee (Research) | Universitat Pompeu Fabra Departament de Ciences Experimentals i de la Salut, Spain |
| Universitat Pompeu Fabra Departament de Ciences Experimentals i de la Salut, Spain | ||
| 2005/02 - 2005/06 | Research Trainee (Research) | European Molecular Biology Laboratory, Italy |
| European Molecular Biology Laboratory, Italy | ||
| 2004 - 2004 | Research Trainee (Research) | Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal |
| Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal |
Projects
Grant
| Designation | Funders | |
|---|---|---|
| 2023/01 - Current | The contribution of immune aging to skeletal muscle regenerative failure
28640
Co-Principal Investigator (Co-PI)
Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal
|
AFM-Téléthon
Under evaluation
|
| 2024/03/01 - 2029/02/28 | immSC-AgingFate: The Interplay of Aging, Immune Signaling and Stem Cell Function
101126073
Principal investigator
Instituto de Medicina Molecular, Portugal
|
European Research Council
Ongoing
|
| 2023/12/31 - 2026/12/30 | Immune regulation of skeletal muscle metabolic health and exercise response in aging
HR23-00881
Principal investigator
Instituto de Medicina Molecular, Portugal
|
"la caixa" Foundation
Ongoing
|
| 2024/01/01 - 2025/06/30 | Deciphering the failure of stem cell engraftment in aged organs
2023 Breakthrough Idea Award
Co-Principal Investigator (Co-PI)
Instituto de Medicina Molecular, Portugal
|
Ongoing
|
| 2020/01/01 - 2024/12/31 | Mechanisms of tissue ageing and repair: roadblocks to stem cell-based therapies
IG4448
Principal investigator
Instituto de Medicina Molecular, Portugal
|
European Molecular Biology Organization - EMBO
Ongoing
|
| 2021/01/01 - 2023/12/31 | Rejuvenating Strategies for Stem Cell-Based Therapies in the Aged Skeletal Muscle
PTDC/MED-OUT/8010/2020
Principal investigator
Instituto de Medicina Molecular, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
| 2022/01/01 - 2023/06/30 | Immune regulation of tissue repair during aging
EXPL/MED-OUT/1601/2021
Co-Principal Investigator (Co-PI)
Instituto de Medicina Molecular, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
| 2019/04/01 - 2022/03/31 | New mechanisms driving stem cell ageing
LCF/BQ/PI19/11690006
Principal investigator
Instituto de Medicina Molecular, Portugal
|
"la caixa" Foundation
Concluded
|
| 2016/06/01 - 2017/05/31 | Targeting Inflammaging with Mesencephalic Astrocyte-derived Neurotrophic Factor (MANF).
Post-doc
Buck Institute for Research on Aging, United States
|
National Institutes of Health
Concluded
|
Contract
| Designation | Funders | |
|---|---|---|
| 2020 - 2022 | MANF role in bone marrow hematopoiesis
iMM-Genentech SRA
Principal investigator
Instituto de Medicina Molecular, Portugal
|
Genentech Inc
Concluded
|
Outputs
Publications
| Book chapter |
|
| Journal article |
|
| Preprint |
|
| Thesis / Dissertation |
|
Intellectual property
| Patent |
|
Activities
Oral presentation
| Presentation title | Event name Host (Event location) |
|
|---|---|---|
| 2023/10/13 | The Interplay of Aging, Immune Signaling and Stem Cell Function | EMBO Young Scientists' Forum
European Molecular Biology Organization (Lisbon, Portugal)
|
| 2023/06/21 | Rejuvenating Strategies for stem cell-based therapies in aging | iBiMED Seminars
University of Aveiro (Aveiro, Portugal)
|
| 2020 | The role of MANF in ageing and tissue repair | HiLIFE webinar / Viikki Monday Seminar
University of Helsinki (Helsinki, Finland)
|
| 2019 | MANF regulates immune homeostasis in aging and protects against liver damage | Nature Conference: Ageing, Health & Rejuvenation
Nature (Rotterdam, Netherlands)
|
| 2015/11 | Piwi is required to limit exhaustion of aging somatic stem cells | Bay Area Aging Meeting Fall 2015
Stanford University (Palo Alto, United States)
|
| 2012/04 | Insights into aged satellite cell biology | Optistem/Endostem 2012 Annual Meeting
(Sitges, Spain)
|
| 2011 | Bmi1-p16INK4A axis in satellite cell self-renewal in aging | Third Myoage workshop “Inflammation and EMC remodeling in ageing”
Myoage (Barcelona, Spain)
|
Supervision
| Thesis Title Role |
Degree Subject (Type) Institution / Organization |
|
|---|---|---|
| 2024 - Current | Immune-stem cell interactions in skeletal muscle exercise response during aging
Supervisor
|
Sorbonne Université, France
|
| 2023 - Current | New mechanisms of muscle stem cell functional decline and their impact on skeletal muscle ageing
Supervisor of Inês Martins
|
Biomedical Sciences (PhD)
Instituto de Medicina Molecular, Portugal
|
| 2023 - Current | Alterations of cross-talk between immune and stem cells in skeletal muscle aging and regeneration
Supervisor of Tiago Costa
|
Biomedical Sciences (PhD)
Instituto de Medicina Molecular, Portugal
|
| 2022 - Current | Rejuvenation of immune signalling to improve skeletal muscle repair
Co-supervisor of Neuza Sousa
|
Biomedical Sciences (PhD) |
| 2021 - Current | Comparative characterization of skeletal muscle phenotype in mice during aging and in MANF loss of function conditions
Co-supervisor of Barbara Pereira
|
Medicine (Master)
Universidade de Lisboa Faculdade de Medicina, Portugal
|
| 2023 - 2033 | MANF in skeletal muscle homeostasis and repair
Supervisor of Linde Verbiest
|
Farmaceutical & biological laboratory sciences (Degree)
UC Leuven-Limburg, Belgium
|
| 2022 - 2023 | Epigenetic regulation of intestinal stem cell aging in Drosophila melanogaster
Supervisor of Mariana Martins
|
Tecnologias Clínico-Laboratoriais
(Master)
Instituto Politécnico de Lisboa Escola Superior de Tecnologia da Saúde de Lisboa, Portugal
|
| 2022 - 2023 | The role of the immune system in MuSC aging during regeneration
Supervisor of Filipa Lagoa
|
Biomedical Research (Master)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
|
| 2021 - 2022 | Mechanisms of immune modulation in muscle repair
Supervisor of Margarida Bras
|
MS in molecular genetics and Biomedicine (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
|
| 2020 - 2022 | Regulation of skeletal muscle repair by MANF
Supervisor of Neuza Sousa
|
MS in molecular genetics and Biomedicine (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
|
| 2021 - 2021 | Immune modulation of muscle regeneration
Co-supervisor of Lea Weiler-Tersch
|
Universität zu Köln, Germany
|
| 2020 - 2020 | The role of MANF in skeletal muscle aging and repair
Supervisor of Lieselot Geernaert
|
Bachelor Programme of Biomedical Laboratory Technology (Degree)
UC Leuven-Limburg, Belgium
|
| 2020 - 2020 | MANF and immune modulation in macrophages
Co-supervisor of Audrey Kahn
|
Molecular and Cellular Biology (Master)
Sorbonne Université, France
|
| 2017 - 2019 | Systemic Inflammation: a regulator of intestinal stem cell homeostasis
Co-supervisor of Cagsar Apaydin
|
Stem Cell Science (Master)
San Francisco State University, United States
|
Event participation
| Activity description Type of event |
Event name Institution / Organization |
|
|---|---|---|
| 2022/04 - Current | Participation and Poster presentation " Aging disrupts MANF-mediated immune modulation during skeletal muscle repair" by student
N. Sousa at EMBO Workshop: Muscle formation, maintenance, regeneration and pathology
Conference
|
EMBO Workshop: Muscle formation, maintenance, regeneration and pathology
European Molecular Biology Organization - EMBO, Germany
|
| 2018/09 - 2018/09 | Poster presentation "MANF is an evolutionarily conserved anti-geronic factor" at EMBO Conference: The molecular and cellular
basis of regeneration and tissue repair
Conference
|
EMBO Conference: The molecular and cellular basis of regeneration and tissue repair
European Molecular Biology Organization - EMBO, Germany
|
| 2018/05 - 2018/05 | Poster presentation "MANF is an evolutionarily conserved anti-geronic factor" at Bay Area Aging Meeting Spring 2018
Meeting
|
Bay Area Aging Meeting |
| 2017/10 - 2017/10 | Poster presentation "MANF is a systemic regulator of metabolic and immune homeostasis during aging" at Champalimaud Research
Symposium 2017
Symposium
|
Champalimaud Research Symposium 2017
Fundação Champalimaud, Portugal
|
| 2016/08 - 2016/08 | Poster presentation "Piwi is required to limit exhaustion of aging somatic stem cells" at Gordon Research Conference - Tissue
Niches & Resident Stem Cells in Adult Epithelia
Conference
|
Gordon Research Conference - Tissue Niches & Resident Stem Cells in Adult Epithelia |
| 2015/06 - 2015/06 | Poster Presentation "Piwi mediated control of genomic integrity regulates stem cell maintenance in the aged Drosophila midgut"
at Else Kroner-Fresenius Symposium on Adult stem cells in aging, disease and cancer
Symposium
|
Else Kroner-Fresenius Symposium on Adult stem cells in aging, disease and cancer |
| 2013/11 - 2013/11 | Poster presentation "Piwi is required for intestinal stem cell maintenance and control of retrotransposon mobilization in
the Drosophila midgut " at Bay Area Aging Meeting Fall 2013
Meeting
|
Bay Area Aging Meeting |
| 2013/09 - 2013/09 | Poster presentation "Piwi is required for intestinal stem cell maintenance and control of retrotransposon mobilization in
the Drosophila midgut " at CSHL Meeting: Stem Cell Biology
Meeting
|
CSHL Meeting: Stem Cell Biology |
| 2010/09 - 2010/09 | Poster presentation "Study of Bmi1 role in muscle senescence " at First Myoage workshop “Tor, caloric restriction and anabolism
in ageing”
Workshop
|
First Myoage workshop “Tor, caloric restriction and anabolism in ageing” |
| 2010/05 - 2010/05 | Poster presentation "Gene networks regulated by p38a in skeletal myogenesis " at Conference New Directions in Biology and
Disease of Skeletal Muscle
Conference
|
New Directions in Biology and Disease of Skeletal Muscle |
| 2008/10 - 2008/10 | Poster presentation "Dissecting the function of MAP kinase phosphatase-1 (MKP-1) in skeletal muscle regeneration and growth
" at CNIO Special workshop "Stress Signalling and Cancer"
Workshop
|
CNIO Special workshop "Stress Signalling and Cancer" |
| 2008/09 - 2008/09 | Poster presentation "Dissecting the function of MAP kinase phosphatase-1 (MKP-1) in skeletal muscle regeneration and growth"
at EMBO Conference 2008: The molecular and cellular mechanisms regulating skeletal muscle development and regeneration
Conference
|
EMBO Conference 2008: The molecular and cellular mechanisms regulating skeletal muscle development and regeneration |
Jury of academic degree
| Topic Role |
Candidate name (Type of degree) Institution / Organization |
|
|---|---|---|
| 2023/06/26 | The aging of skeletal muscle: morphological experimental approaches
(Thesis) Arguer
|
Maria Lacavala (PhD)
Università degli Studi di Verona, Italy
|
| 2022/07 | Cellular senescence in skeletal muscle regeneration, ageing and disease
(Thesis) Main arguer
|
Victoria Moiseeva (PhD)
Universitat Pompeu Fabra Departament de Ciences Experimentals i de la Salut, Spain
|
Ad Hoc journal article review
| Journal title (ISSN) | Publisher | |
|---|---|---|
| 2023 - 2033 | Nature Aging | |
| 2023 - 2024 | iScience | |
| 2022 - 2022 | Advanced Biology | |
| 2021 - 2021 | The FEBS Journal | |
| 2021 - 2021 | Rejuvenation Research | |
| 2020 - 2020 | Journal of Gerontology: Biological Sciences |
Committee member
| Activity description Role |
Institution / Organization | |
|---|---|---|
| 2022 - Current | PhD Thesis Committee of Ana Isidro | Universidade de Lisboa Faculdade de Medicina, Portugal |
| 2022 - Current | PhD Thesis Committee of Joao Moreira | Universidade de Lisboa Faculdade de Medicina, Portugal |
Course / Discipline taught
| Academic session | Degree Subject (Type) | Institution / Organization | |
|---|---|---|---|
| 2021 - Current | Lecture: Rejuvenating Strategies for stem cell-based therapies in aging - PhD Advanced Course in Stem cell Technologies | PhD Advanced Course in Stem cell Technologies (Doutoramento) | Universidade de Lisboa Faculdade de Farmácia, Portugal |
| 2021 - Current | Towards a Creative and Critical Mind - Aging and Tissue Repair | LisbonBiomed PhD Course | Instituto de Medicina Molecular, Portugal |
| 2022 - 2022 | Lecture: "Regenerative decline of stem cells in sarcopenia " | Cell and Molecular Mechanisms of Aging and Associated Diseases Advanced course (Doutoramento) | Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal |
| 2020 - 2020 | Lecture: Rejuvenating Strategies for Stem Cell-Based Therapies in Aging - Stem cell Biology and technologies Master course | Biologia Evolutiva e do Desenvolvimento (Mestrado) | Universidade de Lisboa Faculdade de Ciências, Portugal |
Interview (newspaper / magazine)
| Activity description | Newspaper / Forum | |
|---|---|---|
| 2023 | Interview within the article "Como ser jovem sempre: as repostas da ciência da longevidade" | Prevenir |
| 2021 | Career path Interview | Jornal Publico |
| 2020 | Interview within the article "Jovens para sempre" | Jornal Expresso |
| 2020 | Interview within the article "E se pudermos voltar a ter a força muscular que perdemos com a idade?" | Jornal Observador |
Interview (tv / radio show)
| Program | Topic | |
|---|---|---|
| 2023 - Current | Participation in the radio show in Observador "Mentes brilhantes - Envelhecimento: Aula prática" | Aging |
| 2021 - Current | Interview on Radio Observador program "Mentes brilhantes" about the research supported by la Caixa Junior leader felowship | |
| 2020 - Current | Interview on Antena 1 about EMBO IG award |
Mentoring / Tutoring
| Topic | Student name | |
|---|---|---|
| 2024 - Current | Immune-stem cell interactions in skeletal muscle exercise response during aging (Co-Supervision of Master Thesis work) | Ana Margarida Gomes |
| 2023 - 2023 | Functional decline of immune cells during regeneration in aging (Co-Supervision of Master Thesis work) | Isabel Encarnação |
| 2022 - 2023 | Mechanisms of MANF-mediated immune modulation in tissue repair (Co-Supervision of Master Thesis work) | Beatriz Jorge |
| 2021 - 2023 | The role of immune signaling in age-related stem cell dysfunction (Co-Supervision of Master Thesis work) | Ana Sousa |
| 2021 - 2022 | Peroxisomal modulation of the immune response in aging and tissue repair (Co-Supervision of Master Thesis work) | Debora Castro |
| 2020 - 2021 | Hemocyte mediated tissue repair in Drosophila | Julia Fernandes |
| 2017 - 2017 | Stem cells and Aging | Emilie Baxter |
| 2015 - 2015 | Intestinal Stem cell aging | Joshua Kramer |
Other jury / evaluation
| Activity description | Institution / Organization | |
|---|---|---|
| 2022 - Current | Grant Reviewer (HRB, Ireland) | Health Research Board, Ireland |
| 2022 - Current | Gran Reviewer (NRF, Singapore) | National Research Foundation, Singapore |
| 2021 - 2022 | Grant and Fellowship reviewer (DFG, Germany) | Deutsche Forschungsgemeinschaft, Germany |
Distinctions
Award
| 2023 | FCT Stimulus of Scientific Employment - Assistant Researcher
Fundação para a Ciência e a Tecnologia, Portugal
|
| 2019 | Poster Prize from Nature Review Molecular Cell Biology at Nature Conference 2019 on Ageing, Health and Rejuvenation |
| 2019 | la Caixa Junior Leader fellowship
"la caixa" Foundation, Spain
|
| 2018 | EMBO travel award for EMBO regeneration conference “The Molecular & Cellular Basis of Regeneration and Tissue Repair”
European Molecular Biology Organization - EMBO, Germany
|
| 2018 | Prize for Best Poster at Bay Area Aging meeting |
| 2017 | Champalimaud Research Symposium 2017 Travel award
Fundação Champalimaud, Portugal
|
| 2016 | Glenn Foundation Postdoctoral Research Training Fellowship in the Biology of Aging
Glenn Foundation for Medical Research, United States
|
| 2015 | Travel Award: VII. Else Kröner-Fresenius Symposium on Adult Stem Cells in Aging, Diseases, and Cancer
Else Kröner-Fresenius-Stiftung, Germany
|
| 2015 | City of barcelona award to “Geriatric muscle stem cells switch reversible quiescence into senescence” |
| 2015 | La Vanguardia of Science Award to “Geriatric muscle stem cells switch reversible quiescence into senescence” |
| 2007 | PhD Fellowship
Fundação para a Ciência e a Tecnologia, Portugal
|
Title
| 2012 | PhD awarded ‘cum laude’
Universitat Pompeu Fabra, Spain
|
Other distinction
| 2020 | EMBO Installation Grant
European Molecular Biology Organization - EMBO, Germany
|